{"title":"Photocatalytic Degradation of Typical Fibrates by N and F Co-Doped TiO2 Nanotube Arrays Under Simulated Sunlight Irradiation","authors":"Xiangyu Chen, Hao Zhong, Juanjuan Yao, Jingye Gan, Haibing Cong, Tengyi Zhu","doi":"10.3390/w17152261","DOIUrl":"https://doi.org/10.3390/w17152261","url":null,"abstract":"Fibrate pharmaceuticals (fibrates), as a widespread class of emerging contaminants, pose potential risks to both ecological systems and human health. The photocatalytic system based on nitrogen (N) and fluorine (F) co-doped TiO2 nanotube arrays (NF-TNAs) provides a renewable solution for fibrate pharmaceutical removal from water, powered by inexhaustible sunlight. In this study, the degradation of two typical fibrates, i.e., bezafibrate (BZF) and ciprofibrate (CPF), under simulated sunlight irradiation through NF-TNAs were investigated. The photocatalytic degradation of BZF/CPF was achieved through combined radical and non-radical oxidation processes, while the generation and reaction mechanisms of associated reactive oxygen species (ROS) were examined. Electron paramagnetic resonance detection and quenching tests confirmed the existence of h+, •OH, O2•−, and 1O2, with O2•− playing the predominant role. The transformation products (TPs) of BZF/CPF were identified through high-resolution mass spectrometry analysis combined with quantum chemical calculations to elucidate the degradation pathways. The influence of co-existing ions and typical natural organic matters (NOM) on BZF/CPF degradation were also tested. Eventually, the ecological risk of BZF/CPF transformation products was assessed through quantitative structure–activity relationship (QSAR) modeling, and the results showed that the proposed photocatalytic system can largely alleviate fibrate toxicity.","PeriodicalId":20443,"journal":{"name":"Proceedings","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147887128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ProceedingsPub Date : 2025-06-10DOI: 10.22318/icls2025.189455
Amber Simpson, Soo Hyeon Kim, Cianna Burr
{"title":"Playful Uncertainty: Parents as STEM Educators in the Home","authors":"Amber Simpson, Soo Hyeon Kim, Cianna Burr","doi":"10.22318/icls2025.189455","DOIUrl":"https://doi.org/10.22318/icls2025.189455","url":null,"abstract":"This study examined playful uncertainties-moments when parents feigned uncertainty-to foster children's engineering development in their home environment.Grounded in sociocultural theories of guided participation and family culture, we conducted a case study of four families.Findings suggest that playful uncertainties empowered children to take initiative, explore, and refine their understanding through collaborative discovery and problem-solving.This study also positioned parents as transformative agents, using playful uncertainties as creative epistemic support. PurposeParents and caregivers play a unique role in supporting their children as science, technology, engineering, and mathematics (STEM) learners, from the questions they pose (e.g., Simpson et al., 2022) to the epistemic challenges they present (Kim & Simpson, 2023) to the resources and access they provide (e.g., Dou et al., 2019).In this paper, we add to this knowledge base by considering the role of parents' playful uncertainties when in engaging in engineering design tasks in home environments.Specifically, we address the following: What is the role of parents' use of playful uncertainties in supporting children's engagement as engineering learners?In this study, we define playful uncertainties as moments in which parents feigned uncertainty (i.e., confusion, lack of knowledge) during the engineering design process.Informed by Rogoff et al.'s (1993) concept of guided participation and Keifert's (2021) research on family culture within moments of inquiry, we argue that playful uncertainties within family interactions empower children to take initiative, explore, and refine their understanding through collaborative discovery and problem-solving, particularly within an engineering context.","PeriodicalId":20443,"journal":{"name":"Proceedings","volume":"1 1","pages":"2535-2537"},"PeriodicalIF":0.0,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://repository.isls.org//bitstream/1/11505/1/ICLS2025_2535-2537.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147900139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ProceedingsPub Date : 2025-02-26DOI: 10.3390/proceedings2025114004
Madeline G Reinecke, Fransisca Ting, Julian Savulescu, Ilina Singh
{"title":"The Double-Edged Sword of Anthropomorphism in LLMs <sup>†</sup>.","authors":"Madeline G Reinecke, Fransisca Ting, Julian Savulescu, Ilina Singh","doi":"10.3390/proceedings2025114004","DOIUrl":"10.3390/proceedings2025114004","url":null,"abstract":"<p><p>Humans may have evolved to be \"hyperactive agency detectors\". Upon hearing a rustle in a pile of leaves, it would be safer to assume that an agent, like a lion, hides beneath (even if there may ultimately be nothing there). Can this evolutionary cognitive mechanism-and related mechanisms of anthropomorphism-explain some of people's contemporary experience with using chatbots (e.g., ChatGPT, Gemini)? In this paper, we sketch how such mechanisms may engender the seemingly irresistible anthropomorphism of large language-based chatbots. We then explore the implications of this within the educational context. Specifically, we argue that people's tendency to perceive a \"mind in the machine\" is a double-edged sword for educational progress: Though anthropomorphism can facilitate motivation and learning, it may also lead students to trust-and potentially over-trust-content generated by chatbots. To be sure, students do seem to recognize that LLM-generated content may, at times, be inaccurate. We argue, however, that the rise of anthropomorphism towards chatbots will only serve to further camouflage these inaccuracies. We close by considering how research can turn towards aiding students in becoming digitally literate-avoiding the pitfalls caused by perceiving agency and humanlike mental states in chatbots.</p>","PeriodicalId":20443,"journal":{"name":"Proceedings","volume":"114 1","pages":"4"},"PeriodicalIF":0.0,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7617520/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ProceedingsPub Date : 2024-02-02DOI: 10.47489/szmc.v38i1.420
Awais Amjad Hira Aslam, Khurram, Mateen Akram Muhammad, 2. P. M. Rana Muhammad Umar Jameel, Aiman Farogh Anjum Aneeqa Nasir Qureshi, Saba Izhar Fawad, Hameed, Muhammad Ammar, Maham Qazi, Abrar ul, Hassan Pirzada, Consultant Nephrologist
{"title":"Prevalence of Secondary Hyperparathyroidism in Hemo- Dialysis Patients","authors":"Awais Amjad Hira Aslam, Khurram, Mateen Akram Muhammad, 2. P. M. Rana Muhammad Umar Jameel, Aiman Farogh Anjum Aneeqa Nasir Qureshi, Saba Izhar Fawad, Hameed, Muhammad Ammar, Maham Qazi, Abrar ul, Hassan Pirzada, Consultant Nephrologist","doi":"10.47489/szmc.v38i1.420","DOIUrl":"https://doi.org/10.47489/szmc.v38i1.420","url":null,"abstract":"Introduction: One persistent complication of chronic kidney disease is secondary hyperparathyroidism. Early diagnosis of this disease will reduce morbidity in patients undergoing hemodialysis.\u0000Aims & Objectives: To determine the prevalence of secondary hyperparathyroidism in chronic kidney disease patients at National Institute of Kidney Diseases, SZH Lahore.\u0000Place and Duration of Study: A cross sectional study was conducted at Nephrology Department of Shaikh Zayed Hospital (SZH) Lahore after getting approval from Institutional Review Board of National Health Research Complex (NHRC). It was conducted from September 2023 to November 2023 &140 hemo-dialysis patients were selected.\u0000Material & Methods: We measured serum parathyroid hormone, hemoglobin and other variables, at Biochemistry laboratory of Sheikh Zayed Hospital, in 140 hemodialysis patients. Serum samples were measured for PTH levels using ELISA method. The data was analyzed using SPSS version 20.P value ? 0.05 was considered significant.\u0000Results: Fifteen patients had secondary hyperparathyroidism out of 140 hemodialysis patients. Hyperparathyroidism was observed in 10.71 % of the patients. Hyperparathyroidism patients had significantly low calcium, hemoglobin levels & higher phosphate levels.\u0000Conclusion: The prevalence of secondary hyperparathyroidism is low at 10.71% of patients undergoing hemodialysis at National Institute of Kidney Disease, SZH Lahore.","PeriodicalId":20443,"journal":{"name":"Proceedings","volume":"92 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139683463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ProceedingsPub Date : 2024-02-02DOI: 10.47489/szmc.v38i1.414
Ammara Mushtaq Khan, Sughra Zulfiqar, Amna Saleem, Fahim Ahmed Subhani, Ammara Ayub, Tahira Khurram
{"title":"Mean Rise in Hemoglobin After Intravenous Iron Therapy in Children with Iron Deficiency Anemia","authors":"Ammara Mushtaq Khan, Sughra Zulfiqar, Amna Saleem, Fahim Ahmed Subhani, Ammara Ayub, Tahira Khurram","doi":"10.47489/szmc.v38i1.414","DOIUrl":"https://doi.org/10.47489/szmc.v38i1.414","url":null,"abstract":"Introduction: Iron deficiency anemia (IDA) is a significant public health issue in Pakistan, affecting up to 63% of children, as revealed by the Pakistan National Nutritional Survey 2018. While oral iron remains the primary choice, challenges in compliance have led to the consideration of intravenous (IV) iron therapy, particularly iron sucrose. The study discusses the safety and efficacy of IV iron therapy in Pakistani children and aims to broaden our understanding of treating IDA in resource-constrained regions.\u0000Aims & Objectives: To determine the average hemoglobin (Hb) increase in iron-deficient-anemic children aged 01 to 12 years after treatment with intravenous iron sucrose.\u0000Place and Duration of Study: A quasi-experimental study was undertaken at Fauji Foundation Hospital in Rawalpindi, spanning from September 2021 to September 2022.\u0000Material & Methods: The study focused on a cohort of pediatric patients aged between 1 and 12 years, all of whom were diagnosed with iron deficiency anemia and had previously encountered ineffective outcomes with oral iron therapy. In this investigation, the patients received treatment involving intravenous iron sucrose. Subsequently, their progress was diligently monitored after a period of 8 weeks. Improvement in hemoglobin level was assessed at the end of treatment to evaluate its efficacy.Data processing and statistical analysis were carried out using SPSS version 23,p-value of <0.05 indicated statistical significance.\u0000Results: Out of 150 study cases, 96 (64.0 %) were male, while 54 (36.0 %) were female. The mean age of our study cases was 05 ± 2.3 years of these 150 study cases, 74 (49.3 %) belonged to rural areas, and 76 (50.7 %) belonged to urban areas. Poor socioeconomic status was noted in 97 (64.7 %), and 53 (35.3%) were middle-income. A family history of iron deficiency anaemia was recorded in 16 (10.7%). Iron deficiency due to dietary iron insufficiency was reported in 67 (44.7%), Total Parentral Nutrition (TPN) dependencywas seen in 61 (40.7%) and 22 (14.7%) had chronic gastritis. The mean baseline (pretreatment) haemoglobin level was 7.71 ± 0.63 g/dl, while the mean post-treatment haemoglobin level was 10.68 ± 0.60 g / dl (p = 0.001).\u0000Conclusion: After intravenous iron sucrose, we noted a significant rise in paediatric patients' hemoglobin levels, emphasizing its effectiveness and safety. Statistically, we found correlations with age, family history, and causes. Healthcare practitioners should consider injectable iron treatments for better results and reduced health issues in this group.","PeriodicalId":20443,"journal":{"name":"Proceedings","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139869988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ProceedingsPub Date : 2024-02-02DOI: 10.47489/szmc.v38i1.414
Ammara Mushtaq Khan, Sughra Zulfiqar, Amna Saleem, Fahim Ahmed Subhani, Ammara Ayub, Tahira Khurram
{"title":"Mean Rise in Hemoglobin After Intravenous Iron Therapy in Children with Iron Deficiency Anemia","authors":"Ammara Mushtaq Khan, Sughra Zulfiqar, Amna Saleem, Fahim Ahmed Subhani, Ammara Ayub, Tahira Khurram","doi":"10.47489/szmc.v38i1.414","DOIUrl":"https://doi.org/10.47489/szmc.v38i1.414","url":null,"abstract":"Introduction: Iron deficiency anemia (IDA) is a significant public health issue in Pakistan, affecting up to 63% of children, as revealed by the Pakistan National Nutritional Survey 2018. While oral iron remains the primary choice, challenges in compliance have led to the consideration of intravenous (IV) iron therapy, particularly iron sucrose. The study discusses the safety and efficacy of IV iron therapy in Pakistani children and aims to broaden our understanding of treating IDA in resource-constrained regions.\u0000Aims & Objectives: To determine the average hemoglobin (Hb) increase in iron-deficient-anemic children aged 01 to 12 years after treatment with intravenous iron sucrose.\u0000Place and Duration of Study: A quasi-experimental study was undertaken at Fauji Foundation Hospital in Rawalpindi, spanning from September 2021 to September 2022.\u0000Material & Methods: The study focused on a cohort of pediatric patients aged between 1 and 12 years, all of whom were diagnosed with iron deficiency anemia and had previously encountered ineffective outcomes with oral iron therapy. In this investigation, the patients received treatment involving intravenous iron sucrose. Subsequently, their progress was diligently monitored after a period of 8 weeks. Improvement in hemoglobin level was assessed at the end of treatment to evaluate its efficacy.Data processing and statistical analysis were carried out using SPSS version 23,p-value of <0.05 indicated statistical significance.\u0000Results: Out of 150 study cases, 96 (64.0 %) were male, while 54 (36.0 %) were female. The mean age of our study cases was 05 ± 2.3 years of these 150 study cases, 74 (49.3 %) belonged to rural areas, and 76 (50.7 %) belonged to urban areas. Poor socioeconomic status was noted in 97 (64.7 %), and 53 (35.3%) were middle-income. A family history of iron deficiency anaemia was recorded in 16 (10.7%). Iron deficiency due to dietary iron insufficiency was reported in 67 (44.7%), Total Parentral Nutrition (TPN) dependencywas seen in 61 (40.7%) and 22 (14.7%) had chronic gastritis. The mean baseline (pretreatment) haemoglobin level was 7.71 ± 0.63 g/dl, while the mean post-treatment haemoglobin level was 10.68 ± 0.60 g / dl (p = 0.001).\u0000Conclusion: After intravenous iron sucrose, we noted a significant rise in paediatric patients' hemoglobin levels, emphasizing its effectiveness and safety. Statistically, we found correlations with age, family history, and causes. Healthcare practitioners should consider injectable iron treatments for better results and reduced health issues in this group.","PeriodicalId":20443,"journal":{"name":"Proceedings","volume":"121 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139810093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Estimation of Rotavirus Associated Diarrheal Disease Burden Amongst Primary School Children of Sindh","authors":"Jamil Ahmed, Umer Saeed, Asima Ayyub, Zoofishan Imran, Faheem Mahmood, Muhammad Irfan","doi":"10.47489/szmc.v38i1.388","DOIUrl":"https://doi.org/10.47489/szmc.v38i1.388","url":null,"abstract":"Introduction: Human Rotavirus Virus (HRV) is amongst the common enteric viral diarrheal diseases that indirectly or directly influence school-going children in low-income countries. Inadequate information exists on the presence of rotavirus, with reference to drinking water supplies of primary schools in Sindh, Pakistan.\u0000Aims & Objectives: We estimated the risk of rotavirus-associated diarrhea through drinking water. The study further compared the HRV-associated risk of diarrheal disease by a type of water source.\u0000Place and Duration of Study: A cross-sectional survey was conducted in ten representative districts of Sindh from February 2022 to December 2022. The samples for drinking water were collected from primary schools of ten representative districts of Sindh. This study was a part of the WASH Project funded by USAID (USPCASW Seed Grant P-II)\u0000Material & Methods: We selected 425 samples of drinking water from primary schools based on pre-defined selection criteria. We used a Quantitative Microbial Risk Analysis using indicator organisms, i.e., E. coli, to predict the possible health risks of rotavirus. Data was entered and analyzed on SPSS version 26. The graphs were developed using Arc GIS version 3. Morbidity and mortality were predicted using the Quantitative Microbial Risk Assessment (QAMRA) model. Results: Our data revealed that the highest daily risk of HRV-associated diarrhea amongst school children was 11 per 10,000 schoolchildren, resulting in 8.4% annual risk, and the minimum risk was estimated to be 1 in 10,000 children. The burden of diseases for rotavirus using the QAMRA model revealed the severity of the diarrhea. Majority of the children presented with mild diarrhea (86%) followed by severe, and the probability of death was less than <1%. The daily risk of HRV infection was highest (estimated to be 7 and 11%) in pupils of Southern Sindh, with an annual risk of 17.4% to 40%.\u0000Conclusion: Our study concluded that the children in the primary schools of Sindh were exposed to poor drinking water quality. The surface water source poses the highest risk of HRV-related diarrhea to school children. Thus, it is highly recommended that point-of-use drinking water treatment systems be adopted. The water sanitation and hygiene (WASH) resources are interlinked, so each resource impacts the other; hence, schools urgently need to invest in providing adequate WASH facilities to stop enteric virus transmission through drinking water sources.","PeriodicalId":20443,"journal":{"name":"Proceedings","volume":"383 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140471165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Genitourinary / Fecal Fistulae: Etiology, Types and Surgical Outcomes","authors":"Nayyer Sultana, Tayyaba Majeed, Rana Mohammad Iqbal, Tahseen Haider Kazmi, Mirza Zeeshan Sikandar","doi":"10.47489/szmc.v38i1.443","DOIUrl":"https://doi.org/10.47489/szmc.v38i1.443","url":null,"abstract":"Introduction: Genitourinary/ fecal fistula is an abnormal communication between the genital tract and either the urinary tract or the gastrointestinal tract. Among genitourinary fistulae, most common is the vesicovaginal followed by ureterovaginal fistula.\u0000Aims & Objectives: The aim of our study is to determine various causes and types of genitourinary/fecal fistulae and their surgical outcome in our setting.\u0000Place and Duration of Study: A descriptive, retrospective cross-sectional study was conducted at Central Park Teaching Hospital Hospital, Department of Obstetrics and Gynaecology from December 2013-December 2021.\u0000Material & Methods: Total of 77 patients presented with various types of genitourinary/fecal fistulae during the study period. All details as demographic characteristics, type and cause of fistula, route of repair and surgical outcome were taken on a standardized proforma. All data was entered and analyzed in SPSS version 26 for statistical analysis.p-value of less than 0.05 was regarded as significant.\u0000Results: In this study, the age range was from 22 to 62 years with mean age 38.38 + 10.67 years. Mean duration of fistula was computed as 45.47 + 71.31 months with the range of 1 month to 27 years (324 months). Average fistula size was 1.14 + 0.96 cm with the range of 0.25 cm to 3 centimeters. The obstetric causes of fistulae accounted 44% (n=34) while iatrogenic causes were seen in 56% (n=43) of patients. The most common type of fistula was VVF with 53 (69%) patients followed by uretero-vaginal fistula with 08 (10.0%). The least common type of fistula was urethro-vaginal with only 01 (1%) case of 22 years, 05 (7%) patients had RVF and 08 (10%) had vesico-uterine and vesico-cervical fistulae. the overall success rate is 88.3%.\u0000Conclusion: The iatrogenic causes of genitourinary/fecal fistulae are more prevalent than obstetric causes. The successful outcome of fistula repair depends on number of previous attempts of repair and outcome of repair worsen with each number of previous attempts.","PeriodicalId":20443,"journal":{"name":"Proceedings","volume":"528 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140476813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ProceedingsPub Date : 2024-01-31DOI: 10.47489/szmc.v38i1.455
M. B. Ghafoor, Ghulam Mustafa, Hafiz Shahid Latif, Faiza Sarwar, Muhammad Saleem Leghari, Ali Hasnain
{"title":"Oral Water Hydration May Impact Hematocrit and Blood Sugar Levels in Patients with Diabetes Mellitus","authors":"M. B. Ghafoor, Ghulam Mustafa, Hafiz Shahid Latif, Faiza Sarwar, Muhammad Saleem Leghari, Ali Hasnain","doi":"10.47489/szmc.v38i1.455","DOIUrl":"https://doi.org/10.47489/szmc.v38i1.455","url":null,"abstract":"Introduction: Patients of diabetes repeatedly need blood glucose measurement, which may be falsely high due to less water intake and poor hydration of the patients.\u0000Aims & Objectives: To determine the effect of water intake or hydration on hematocrit and blood sugar levels in patients with diabetes mellitus.\u0000Place and Duration of Study: Pathology Department and Diabetic Center of Sheikh Zayed Hospital, Rahim Yar Khan from January 2023 to July 2023.\u0000Material & Methods: It was a cross sectional study conducted in total 75 Type-1 & Type-2 diabetes patients using convenient sampling technique. 5 ml blood samples were drawn before and 20 minutes after oral hydration with 500 ml of oral water in all these patients to determine the effect on hematocrit and blood sugar levels. The data was entered and analyzed on SPSS version 23. Pre and post observations were compared using paired t-test. p-value<0.05 was taken as statistically significant.\u0000Results: The mean value for age and BSR (before and after) of study subjects was 46±11 years, 200±97 mg/dl, and 199±94 mg/dl (p=0.8) respectively. While mean value of HCT before hydration was 39±5.8% and after hydration was 38±6.4% (p=0.006).\u0000Conclusion: Oral water hydration impacted mean hematocrit values in diabetic patients, significantly lowering them whereas their mean BSR values remained unaffected.","PeriodicalId":20443,"journal":{"name":"Proceedings","volume":"311 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140473450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}