Prevalence of Secondary Hyperparathyroidism in Hemo- Dialysis Patients

Awais Amjad Hira Aslam, Khurram, Mateen Akram Muhammad, 2. P. M. Rana Muhammad Umar Jameel, Aiman Farogh Anjum Aneeqa Nasir Qureshi, Saba Izhar Fawad, Hameed, Muhammad Ammar, Maham Qazi, Abrar ul, Hassan Pirzada, Consultant Nephrologist
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Abstract

Introduction: One persistent complication of chronic kidney disease is secondary hyperparathyroidism. Early diagnosis of this disease will reduce morbidity in patients undergoing hemodialysis. Aims & Objectives: To determine the prevalence of secondary hyperparathyroidism in chronic kidney disease patients at National Institute of Kidney Diseases, SZH Lahore. Place and Duration of Study: A cross sectional study was conducted at Nephrology Department of Shaikh Zayed Hospital (SZH) Lahore after getting approval from Institutional Review Board of National Health Research Complex (NHRC). It was conducted from September 2023 to November 2023 &140 hemo-dialysis patients were selected. Material & Methods: We measured serum parathyroid hormone, hemoglobin and other variables, at Biochemistry laboratory of Sheikh Zayed Hospital, in 140 hemodialysis patients. Serum samples were measured for PTH levels using ELISA method. The data was analyzed using SPSS version 20.P value ? 0.05 was considered significant. Results: Fifteen patients had secondary hyperparathyroidism out of 140 hemodialysis patients. Hyperparathyroidism was observed in 10.71 % of the patients. Hyperparathyroidism patients had significantly low calcium, hemoglobin levels & higher phosphate levels. Conclusion: The prevalence of secondary hyperparathyroidism is low at 10.71% of patients undergoing hemodialysis at National Institute of Kidney Disease, SZH Lahore.
血液透析患者继发性甲状旁腺功能亢进症的患病率
简介继发性甲状旁腺功能亢进症是慢性肾脏病的一种长期并发症。对这种疾病的早期诊断将降低血液透析患者的发病率:确定拉合尔深圳医院国家肾脏病研究所慢性肾病患者继发性甲状旁腺功能亢进症的发病率:在获得国家健康研究中心(NHRC)机构审查委员会的批准后,在拉合尔谢赫-扎耶德医院(SZH)肾脏科开展了一项横断面研究。研究时间为2023年9月至2023年11月,选取了140名血液透析患者:我们在谢赫-扎耶德医院的生化实验室测量了 140 名血液透析患者的血清甲状旁腺激素、血红蛋白和其他变量。使用 ELISA 方法测量血清样本中的 PTH 水平。数据使用 SPSS 20 版进行分析。结果:结果:在 140 名血液透析患者中,有 15 名患者患有继发性甲状旁腺功能亢进症。10.71%的患者患有甲状旁腺功能亢进症。甲状旁腺功能亢进症患者的血钙、血红蛋白水平明显偏低,磷酸盐水平较高:继发性甲状旁腺功能亢进症的发病率较低,仅占拉合尔深圳医院国家肾脏病研究所血液透析患者的 10.71%。
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