Polymer International最新文献_第3页

Anti-tumoural activity of 3D printed fluorohydroxyapatite–polylactic acid scaffolds combined with graphene oxide and doxorubicin 氧化石墨烯与阿霉素复合3D打印氟羟基磷灰石-聚乳酸支架的抗肿瘤活性

IF 2.9 4区化学

Polymer International Pub Date : 2025-01-09 DOI: 10.1002/pi.6743

Maissa Agsous, Khireddine Hafit, Sabeha Yala, Busra Oktay, Ayşe Betül Bingöl, İlkay Şenel, Cem Bülent Üstündağ

{"title":"Anti-tumoural activity of 3D printed fluorohydroxyapatite–polylactic acid scaffolds combined with graphene oxide and doxorubicin","authors":"Maissa Agsous, Khireddine Hafit, Sabeha Yala, Busra Oktay, Ayşe Betül Bingöl, İlkay Şenel, Cem Bülent Üstündağ","doi":"10.1002/pi.6743","DOIUrl":"https://doi.org/10.1002/pi.6743","url":null,"abstract":"This study focuses on the synthesis of fluorohydroxyapatite (FHA), and the realization of scaffolds by 3D printing using polylactic acid (PLA) as polymer and graphene oxide (GO). The synthesis of FHA was carried out by the usual sol–gel method. The realization of the 3D scaffold was achieved with the 3D printing method. Four scaffolds were printed with PLA: the first was made with FHA and PLA (FHA/PLA), the second was made with GO in addition to FHA and PLA (FHA/PLA/GO), and the third and fourth ones were the FHA/PLA and FHA/PLA/GO scaffolds coated with electrosprayed hydrogel solution of doxorubicin (DOX) and polyvinyl alcohol (PVA): FHA/PLA/DOX/PVA and FHA/PLA/GO/DOX/PVA. The FHA and GO powders were characterized using Fourier transform infrared analysis and X-ray diffraction analysis. A dissolution study was carried out with different contents of PVA (2.5%, 3% and 4%) to identify the scaffold with the best drug release profile. The 3% w/w PVA hydrogel solution was the best, so the drug release kinetics and drug release mechanism were studied using the most famous mathematical models: zero-order model, Higuchi's model and Korsmeyer–Peppas model (power law model). The porosity of the 3D printed scaffolds was assessed by SEM and, finally, the cellular response of each scaffold on the viability of CDD human fibroblast cells was evaluated using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. The sol–gel synthesis produces FHA, used in the realization of the scaffolds. The scaffolds have mixed porosity (macropores and micropores) promoting cell adhesion and proliferation, as shown by the results of the MTT assay. The addition of GO decreases the cell viability but keeps the scaffolds still biocompatible, and adding both DOX and GO to the FHA/PLA scaffolds has a negative impact on cell viability because DOX and GO remain toxic at the given percentages. © 2025 Society of Chemical Industry.","PeriodicalId":20404,"journal":{"name":"Polymer International","volume":"74 3","pages":"277-285"},"PeriodicalIF":2.9,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143396976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Non-destructive modification of cellulose-based fabrics in aqueous phase for flame-retardant epoxy composite

IF 2.9 4区化学

Polymer International Pub Date : 2025-01-07 DOI: 10.1002/pi.6744

Liyue Zhang, Jingkai Liu, Xiaoling Liu, Jinyue Dai, Xiaoqing Liu, Xiaosu Yi

{"title":"Non-destructive modification of cellulose-based fabrics in aqueous phase for flame-retardant epoxy composite","authors":"Liyue Zhang, Jingkai Liu, Xiaoling Liu, Jinyue Dai, Xiaoqing Liu, Xiaosu Yi","doi":"10.1002/pi.6744","DOIUrl":"https://doi.org/10.1002/pi.6744","url":null,"abstract":"The flame-retardant modification of plant fiber-reinforced composites (PFRCs) is a fundamental requirement for achieving broader industrial applications. However, commonly used modification methods often compromise the fiber mechanical properties or surface reactivity due to structural damage. In this paper, a water-soluble system consisting of phytic acid imidazole salt and biobased benzoxazine was devised to modify a regenerated cellulose fabric through water-phase immersion. Benefiting from the neutral solution and self-assembly coating, the modified fabric (F-RCF) exhibited a typical self-extinguishing behavior while maintaining good structural integrity and mechanical properties. By further combining F-RCF with a DOPO-containing epoxy resin blend (FEB) to prepare a fiber-reinforced green composite (F-RCF/FEB), the results indicated that the co-curing reaction between the modifier and resin matrix contributed to improved interfacial adhesion. This enabled the simultaneous enhancement of tensile modulus (from 9.82 to 11.29 MPa), impact strength (from 6.58 to 7.26 kJ m−2) and interlaminar shear strength (from 11.41 to 13.89 MPa). More importantly, F-RCF/FEB exhibited excellent anti-flammability in terms of a high limiting oxygen index value of 34.3% and a UL-94 V-0 rating, and the peak heat release and total heat release were also markedly reduced by 44.9% and 36.9%, respectively. Mechanism analysis revealed that the modified system effectively prevented the wick effect and provided an inhibitory effect in the gaseous phase, as well as a barrier effect in the condensed phase. This study presents a non-destructive modification strategy for plant fibers, which may also inspire the synchronous enhancement of interfacial compatibility and fire-proof performance of PFRCs. © 2025 Society of Chemical Industry.","PeriodicalId":20404,"journal":{"name":"Polymer International","volume":"74 6","pages":"528-537"},"PeriodicalIF":2.9,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143944881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preparation of polyhydroxyalkanoate nanocomposites for biomedical applications 生物医学用聚羟基烷酸酯纳米复合材料的制备

IF 2.9 4区化学

Polymer International Pub Date : 2025-01-06 DOI: 10.1002/pi.6742

Jia Chen, Chunjie Gong

{"title":"Preparation of polyhydroxyalkanoate nanocomposites for biomedical applications","authors":"Jia Chen, Chunjie Gong","doi":"10.1002/pi.6742","DOIUrl":"https://doi.org/10.1002/pi.6742","url":null,"abstract":"Polyhydroxyalkanoates (PHAs) have been recognized as potential replacements for fossil fuel-based, non-biodegradable plastics. PHAs exhibit properties that are analogous to those of synthetic plastics. The production of PHAs offers a multitude of advantages, primarily due to their biodegradability and biocompatibility. The most naturally occurring form of PHAs are the polyhydroxybutyrates (P(3HB)s). The major limitations of P(3HB)s are their brittle nature and inferior mechanical properties. Hence, these biopolymers have been observed to have limited biotechnological applications. In contrast to P(3HB)s, copolymers of PHAs have almost all the desirable properties, making them suitable for high-end applications such as those in the medical sector. Structural modifications in PHA molecules have expanded the scope of their applications, including in medical implants, wound healing and bone grafts. It is noteworthy that considerable progress has been made in the field of PHA nanocomposites, which are now being explored for their biotechnological applications in drug delivery, tissue engineering and biosensors. The prospects for PHA nanocomposites are also summarized. © 2025 Society of Chemical Industry.","PeriodicalId":20404,"journal":{"name":"Polymer International","volume":"74 5","pages":"405-414"},"PeriodicalIF":2.9,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143809777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thermal decomposition analysis and combustion mechanism investigation of biomass-based polyurethane 生物质基聚氨酯的热分解分析及燃烧机理研究

IF 2.9 4区化学

Polymer International Pub Date : 2024-12-26 DOI: 10.1002/pi.6739

Zhirong Xu, Jing Zhan, Zihui Xu

{"title":"Thermal decomposition analysis and combustion mechanism investigation of biomass-based polyurethane","authors":"Zhirong Xu, Jing Zhan, Zihui Xu","doi":"10.1002/pi.6739","DOIUrl":"https://doi.org/10.1002/pi.6739","url":null,"abstract":"Starch phosphate carbamate was synthesized via a one-pot method using phosphoric acid, urea and starch, and it was added into polyurethane (PU) to replace some polyol. The fire retardancy and thermal stability of the resulting PU system were evaluated by the results of vertical burning test (UL-94), limiting oxygen index (LOI), cone calorimeter (CONE) test and thermogravimetric analysis. Raman spectroscopy and X-ray photoelectron spectroscopy were used to analyze the char layer after the CONE test, and the thermogravimetric–infrared test was used to analyze the gas products at the maximum rate of thermal decomposition. The introduction of 13.7 wt% starch phosphate carbamate (PU-15) in PU enables the system to pass the V-0 rating, with LOI reaching 22.8%. The peak heat release rate of PU-15 decreased by 36.54% compared to PU, and the total heat release of PU-15 was only 27.87 MJ m−2. Starch phosphate carbamate reduces the generation of combustible small molecules during the combustion of the system, producing a more protective char layer. Raman results indicate that starch phosphate carbamate can increase the stability of the char layer. Integrating the results from various tests, the combustion mechanism of PU with starch phosphate carbamate was explored. Starch phosphate carbamate provides a new approach for preparing high-performance PU. © 2024 Society of Chemical Industry.","PeriodicalId":20404,"journal":{"name":"Polymer International","volume":"74 7","pages":"575-582"},"PeriodicalIF":2.9,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144197559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Wet chemical synthesis of nanohydroxyapatite within poly(sodium sulfonated butylene fumarate-co-acrylic acid) as bone scaffold: effects of sulfonate and carboxylic acid groups 纳米羟基磷灰石在聚（磺化富马酸丁二钠-共丙烯酸）内作为骨支架的湿化学合成：磺酸基和羧酸基的影响

IF 2.9 4区化学

Polymer International Pub Date : 2024-12-22 DOI: 10.1002/pi.6738

Nadia Mahmoudzadeh, Hadi Shirali, Faramarz Afshar Taromi

{"title":"Wet chemical synthesis of nanohydroxyapatite within poly(sodium sulfonated butylene fumarate-co-acrylic acid) as bone scaffold: effects of sulfonate and carboxylic acid groups","authors":"Nadia Mahmoudzadeh, Hadi Shirali, Faramarz Afshar Taromi","doi":"10.1002/pi.6738","DOIUrl":"https://doi.org/10.1002/pi.6738","url":null,"abstract":"This study investigates the synthesis, nucleation and modification of biodegradable poly(sodium sulfonated butylene fumarate-co-acrylic acid)/hydroxyapatite nanocomposite scaffolds for bone tissue engineering, with a focus on the effects of incorporating hydrophilic sulfonate and carboxylic acid groups. Poly(butylene fumarate) was sulfonated at varying degrees and used to form nanocomposites through in situ nucleation of nanohydroxyapatite (nHA) in a simulated body fluid solution. Critical parameters such as water absorption, swelling behavior, mechanical properties, nanoparticle dispersion and biocompatibility were evaluated. Water uptake ratios ranged from 2.72 to 6.88 g g−1, while compressive modulus values increased up to 25.9 times compared with the corresponding homopolymers, demonstrating improved mechanical stability. Despite the formation of over 80% nanoparticles, well-distributed nHA, with sizes averaging 39 ± 13 nm, was achieved through the incorporation of sulfonated groups, preventing nanoparticle agglomeration within the scaffold matrix. Additionally, the scaffolds supported human dermal fibroblast adhesion and proliferation, with cell viability remaining high throughout the culture period. These results suggest that the developed nanocomposite scaffolds offer enhanced biocompatibility, mechanical strength and osteogenic potential, making them promising candidates for bone tissue regeneration applications. © 2024 Society of Chemical Industry.","PeriodicalId":20404,"journal":{"name":"Polymer International","volume":"74 5","pages":"434-443"},"PeriodicalIF":2.9,"publicationDate":"2024-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143809928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fabrication and surface characterization of a novel approach for membrane electrode assembly using Nafion/PPy electrochemically coated with copper, nickel and silver

IF 2.9 4区化学

Polymer International Pub Date : 2024-12-12 DOI: 10.1002/pi.6732

Sana Ben Jadi, Abdelqader El Guerraf, Mina El Fazdoune, Khadija Bahend, Maryem Oubella, El Arbi Bazzaoui, Rongguang Wang, Mohammed Bazzaoui

{"title":"Fabrication and surface characterization of a novel approach for membrane electrode assembly using Nafion/PPy electrochemically coated with copper, nickel and silver","authors":"Sana Ben Jadi, Abdelqader El Guerraf, Mina El Fazdoune, Khadija Bahend, Maryem Oubella, El Arbi Bazzaoui, Rongguang Wang, Mohammed Bazzaoui","doi":"10.1002/pi.6732","DOIUrl":"https://doi.org/10.1002/pi.6732","url":null,"abstract":"A novel approach is developed for the preparation of a membrane electrode assembly with low methanol crossover, designed for application in direct methanol fuel cells. This method involves a two-step process starting with the modification of a Nafion membrane through chemical oxidative polymerization of pyrrole, using FeCl3 as an oxidant. Subsequently, galvanostatic electrodeposition of several metals (copper, nickel and silver) was performed on the previously prepared composite membrane (polypyrrole–Nafion). Scanning electron microscopy was conducted to examine the growth evolution, morphology and distribution of the deposited polypyrrole and metals. Additionally, X-ray photoelectron analysis enabled for the identification of elemental composition and chemical states within the coating to confirm the growth evolution, morphology and oxide phases present in the coatings, as well as their structural characteristics. © 2024 Society of Chemical Industry.","PeriodicalId":20404,"journal":{"name":"Polymer International","volume":"74 6","pages":"509-519"},"PeriodicalIF":2.9,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143944557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Insights into electrospun polymeric nanofiber mats: an innovative dressing for wound healing applications 洞察电纺聚合物纳米纤维垫：创面愈合应用的创新敷料

IF 2.9 4区化学

Polymer International Pub Date : 2024-12-12 DOI: 10.1002/pi.6736

Bimal Rajchal, Yub Narayan Thapa, Deepshikha Karki, Prabha Prajapati, Rameshwar Adhikari

{"title":"Insights into electrospun polymeric nanofiber mats: an innovative dressing for wound healing applications","authors":"Bimal Rajchal, Yub Narayan Thapa, Deepshikha Karki, Prabha Prajapati, Rameshwar Adhikari","doi":"10.1002/pi.6736","DOIUrl":"https://doi.org/10.1002/pi.6736","url":null,"abstract":"Wound management is a complex clinical challenge that needs advanced materials and techniques for satisfactory results. Electrospun nanofiber mats have emerged as an innovative alternative for wound healing purposes due to their porous architecture, greater surface area, ease of water absorption, mimicry of the extracellular matrix of natural tissues and tunable mechanical properties. This paper sheds light on recent advances in the fabrication techniques, properties, structural features and application of electrospun polymeric nanofiber mats for wound healing purposes emphasizing the importance of polymer selection and processing parameters in tailoring their physicochemical properties. Furthermore, the review explores the underlying principles of the wound healing process and various approaches to incorporating bioactive agents into nanofiber mats to enhance their biological performance and wound healing potential. The possibility of embedding stimuli-responsive sensors into the nanofiber mats to develop smart mats is also briefly explored. © 2024 Society of Chemical Industry.","PeriodicalId":20404,"journal":{"name":"Polymer International","volume":"74 5","pages":"391-404"},"PeriodicalIF":2.9,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143809693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Special issue. Antimicrobial biopolymers: from synthesis to application 特殊的问题。抗菌生物聚合物：从合成到应用

IF 2.9 4区化学

Polymer International Pub Date : 2024-12-11 DOI: 10.1002/pi.6719

Ernesto Oyervides-Muñoz, Eder Iván Martínez-Mora

引用次数: 0

Reinventing the wheel: the importance of knowing the literature 重新发明轮子：了解文学的重要性

IF 2.9 4区化学

Polymer International Pub Date : 2024-12-11 DOI: 10.1002/pi.6731

Timothy E Long

引用次数: 0

Transport of penetrants in polymeric materials 渗透剂在聚合物材料中的迁移