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Vivo application of a portable plasma generator in infected wound healing 便携式等离子发生器在感染性伤口愈合中的活体应用
IF 3.5 3区 物理与天体物理
Plasma Processes and Polymers Pub Date : 2024-07-05 DOI: 10.1002/ppap.202400071
Mingze Dang, Yiqian Li, Lanlan Nie, Feng Zhao, Shaohui Jin, Xi Chen, Xinpei Lu, Lu Gan
{"title":"Vivo application of a portable plasma generator in infected wound healing","authors":"Mingze Dang, Yiqian Li, Lanlan Nie, Feng Zhao, Shaohui Jin, Xi Chen, Xinpei Lu, Lu Gan","doi":"10.1002/ppap.202400071","DOIUrl":"https://doi.org/10.1002/ppap.202400071","url":null,"abstract":"In this study, a portable plasma generator produced large‐area air plasma for treating infected wounds in BALB/c mice. Different plasma treatment times (30 s, 1 min, 3 min, and 4.5 min) were applied daily until the wounds healed completely. Results showed reduced inflammation and increased vascular endothelial growth factor (VEGF) expression in tissues treated for 1 and 3 min, promoting blood vessel proliferation and collagen fiber synthesis. However, treatment for 30 s and 4.5 min worsened inflammation and decreased VEGF expression. Overall, a 1‐min treatment was the most effective in promoting wound healing. Cold plasma shows promise for healing infected wounds, with treatment duration being a crucial factor.","PeriodicalId":20135,"journal":{"name":"Plasma Processes and Polymers","volume":"13 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141546979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of short‐term treatment of some cereal grains with atmospheric pressure Ar–O2 and Ar–air plasma 用常压氩-O2 和氩-空气等离子体短期处理某些谷物的效果
IF 3.5 3区 物理与天体物理
Plasma Processes and Polymers Pub Date : 2024-07-05 DOI: 10.1002/ppap.202400093
Andris Martinovs, Andris Martinovs, Gita Rēvalde, Diāna Dombrovska, Guntis Koļčs, Rasma Tretjakova, Edgars Zaicevs
{"title":"Effect of short‐term treatment of some cereal grains with atmospheric pressure Ar–O2 and Ar–air plasma","authors":"Andris Martinovs, Andris Martinovs, Gita Rēvalde, Diāna Dombrovska, Guntis Koļčs, Rasma Tretjakova, Edgars Zaicevs","doi":"10.1002/ppap.202400093","DOIUrl":"https://doi.org/10.1002/ppap.202400093","url":null,"abstract":"A study of the grain surface structure and seedling development of wheat, barley, oats, and rye depending on short‐term treatment of their grains in Ar–O<jats:sub>2</jats:sub> and Ar–air cold plasma and post‐discharge with a perspective of implementation of the method on an industrial scale is presented. Following parameters are monitored: chemical composition of plasma, grain surface roughness, germination rate, seed germination, length of seedlings, dry mass of stems and roots, as well as vigor index II. The results show that even an 8.7‐s‐long treatment of grains in postdischarge can improve the root system of seedlings, increasing its mass up to 16.2% (barley), 15.6% (rye), and 14.3% (wheat) within the first 10 days after sowing.","PeriodicalId":20135,"journal":{"name":"Plasma Processes and Polymers","volume":"83 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141569945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A fast and reliable microplate reader assay to assess the antiviral efficacy of cold plasma devices 快速可靠的微孔板阅读器测定法，用于评估冷血浆设备的抗病毒功效
IF 3.5 3区 物理与天体物理
Plasma Processes and Polymers Pub Date : 2024-07-05 DOI: 10.1002/ppap.202400104
Sander Bekeschus, Henry Skowski, Veronika Hahn, Robert Bansemer, Torsten Gerling, Klaus‐Dieter Weltmann, Thomas von Woedtke
{"title":"A fast and reliable microplate reader assay to assess the antiviral efficacy of cold plasma devices","authors":"Sander Bekeschus, Henry Skowski, Veronika Hahn, Robert Bansemer, Torsten Gerling, Klaus‐Dieter Weltmann, Thomas von Woedtke","doi":"10.1002/ppap.202400104","DOIUrl":"https://doi.org/10.1002/ppap.202400104","url":null,"abstract":"Spurred by global COVID‐19, work in recent years has demonstrated that various devices based on technology generating cold plasma are capable of reducing the infectivity of virus particles. There is great potential in this approach, which is, however, hampered by the ability of most cold plasma science laboratories to test for antiviral effects of their individual plasma sources in sophisticated mammalian cell test systems. To this end, we developed a quick, simple, and fast assay system based on bacteriophages and their ability to lyse bacterial hosts, which can be monitored in readily available microplate readers. We successfully demonstrated the principal ability of this approach using two types of plasma jets, different microplate readers, and two different bacteriophage strains.","PeriodicalId":20135,"journal":{"name":"Plasma Processes and Polymers","volume":"90 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141546981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Time‐sharing synergy of NOx mode and O3 mode air discharges for efficient and pollution‐free disinfection NOx 模式和 O3 模式空气排放的分时协同作用，实现高效无污染消毒
IF 3.5 3区 物理与天体物理
Plasma Processes and Polymers Pub Date : 2024-07-05 DOI: 10.1002/ppap.202400083
Zifeng Wang, Luge Wang, Pengfei Zhang, Dingxin Liu, Yue Feng, Qiuyi Yue, Yujie He, Shenghang Xu, Xiangyu Wang, Dandan Pei, Jishen Zhang, Li Guo, Mingzhe Rong
{"title":"Time‐sharing synergy of NOx mode and O3 mode air discharges for efficient and pollution‐free disinfection","authors":"Zifeng Wang, Luge Wang, Pengfei Zhang, Dingxin Liu, Yue Feng, Qiuyi Yue, Yujie He, Shenghang Xu, Xiangyu Wang, Dandan Pei, Jishen Zhang, Li Guo, Mingzhe Rong","doi":"10.1002/ppap.202400083","DOIUrl":"https://doi.org/10.1002/ppap.202400083","url":null,"abstract":"As an alternative disinfection technology, air plasma is limited to achieve wider application due to its restricted disinfection level and hazardous by‐products including O<jats:sub>3</jats:sub> and NO<jats:sub>x</jats:sub>. In this work, a time‐sharing synergy strategy is proposed, where NO and NO<jats:sub>2</jats:sub> are first generated by a dielectric barrier discharge reactor in NO<jats:sub>x</jats:sub> mode, and then the discharge is switched into O<jats:sub>3</jats:sub> mode by increasing flowrate, thus producing large amounts of high‐valence NO<jats:sub>x</jats:sub> for efficient disinfection in sealed space. The disinfection effect of time‐sharing synergy is about 2 logs higher than using single O<jats:sub>3</jats:sub> or NO<jats:sub>x</jats:sub> mode with the same discharge power. The concentration of high‐valence NO<jats:sub>x</jats:sub> is highly correlated with disinfection effect. Finally, all disinfection ingredients are removed after 2‐min gas‐washing and heating.","PeriodicalId":20135,"journal":{"name":"Plasma Processes and Polymers","volume":"42 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141569944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An experimental and computational investigation of discharge mode transitions in a partially magnetized radio frequency capacitively coupled oxygen discharge 部分磁化射频电容耦合氧放电中放电模式转换的实验和计算研究
IF 3.5 3区 物理与天体物理
Plasma Processes and Polymers Pub Date : 2024-07-03 DOI: 10.1002/ppap.202300219
Jia‐Rui Liu, Xiao‐Kun Wang, Li Wang, Kai Zhao, Yong‐Xin Liu, Yuan‐Hong Song, You‐Nian Wang
{"title":"An experimental and computational investigation of discharge mode transitions in a partially magnetized radio frequency capacitively coupled oxygen discharge","authors":"Jia‐Rui Liu, Xiao‐Kun Wang, Li Wang, Kai Zhao, Yong‐Xin Liu, Yuan‐Hong Song, You‐Nian Wang","doi":"10.1002/ppap.202300219","DOIUrl":"https://doi.org/10.1002/ppap.202300219","url":null,"abstract":"A magnetized capacitively coupled oxygen plasma was studied synergistically using phase resolved optical emission spectroscopy and particle‐based kinetic simulation. Discharge mode transitions from ambipolar mode into drift mode and finally into α mode induced by increasing the magnetic field were observed at different driving frequencies and different electrode gaps. The simulation results demonstrate that the discharge operating in the same mode exhibits a similar degree of electronegativity. By increasing driving frequency or electrode gap, the same discharge mode transition tends to occur at a lower magnetic field, and, meanwhile, the high electric field and electron power absorption shift from the bulk region to the sheath edge.","PeriodicalId":20135,"journal":{"name":"Plasma Processes and Polymers","volume":"109 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141546986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Low‐carbon pyrolysis of vacuum gas oil by non‐thermal plasma 利用非热等离子体对真空瓦斯油进行低碳热解
IF 3.5 3区 物理与天体物理
Plasma Processes and Polymers Pub Date : 2024-07-03 DOI: 10.1002/ppap.202400061
Evgeniy Yurevich Titov, Ivan Vasilevich Bodrikov, Alexander Leonidovich Vasiliev, Anna Gennadievna Ivanova, Andrey Leonidovich Golovin, Dmitry Alekseevich Shirokov, Yuriy Alekseevich Kurskii, Dmitry Yurievich Titov, Evgenia Ruslanovna Bodrikova
{"title":"Low‐carbon pyrolysis of vacuum gas oil by non‐thermal plasma","authors":"Evgeniy Yurevich Titov, Ivan Vasilevich Bodrikov, Alexander Leonidovich Vasiliev, Anna Gennadievna Ivanova, Andrey Leonidovich Golovin, Dmitry Alekseevich Shirokov, Yuriy Alekseevich Kurskii, Dmitry Yurievich Titov, Evgenia Ruslanovna Bodrikova","doi":"10.1002/ppap.202400061","DOIUrl":"https://doi.org/10.1002/ppap.202400061","url":null,"abstract":"The constant growth in the share of renewable electricity and the need to reduce CO<jats:sub>2</jats:sub> emissions create prospects for the development of non‐thermal plasma (NTP) pyrolysis of heavy oil. NTP pyrolysis requires only electricity and does not require heating of raw materials to high temperatures, which significantly reduces the carbon footprint during processing. This paper investigates the characteristics of NTP pyrolysis of vacuum gas oil under the action of electric microsecond discharges in the liquid phase, depending on the voltage of the current source 300–700 V to optimize energy consumption, conversion of raw materials, and increase the yield of commercial demand products.","PeriodicalId":20135,"journal":{"name":"Plasma Processes and Polymers","volume":"76 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141546983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cold plasma treatment of patient‐derived chronic lymphocytic B‐cell leukemia enhances cytotoxic T‐cell proliferation 冷等离子体治疗患者源性慢性淋巴细胞 B 细胞白血病可增强细胞毒性 T 细胞增殖
IF 3.5 3区 物理与天体物理
Plasma Processes and Polymers Pub Date : 2024-07-03 DOI: 10.1002/ppap.202400008
Monireh Golpour, Hossein Asgarian‐Omran, Haleh Akhavan‐Niaki, Mina Alimohammadi, Maryam Alizadeh‐Forutan, Farshad Sohbatzadeh, Sander Bekeschus, Alireza Rafiei
{"title":"Cold plasma treatment of patient‐derived chronic lymphocytic B‐cell leukemia enhances cytotoxic T‐cell proliferation","authors":"Monireh Golpour, Hossein Asgarian‐Omran, Haleh Akhavan‐Niaki, Mina Alimohammadi, Maryam Alizadeh‐Forutan, Farshad Sohbatzadeh, Sander Bekeschus, Alireza Rafiei","doi":"10.1002/ppap.202400008","DOIUrl":"https://doi.org/10.1002/ppap.202400008","url":null,"abstract":"Cold physical plasma, a partially ionized gas, has been shown to be effective in treating chronic wounds and cancer. However, there is limited research on plasma exposure of leukemia cell lines, such as chronic lymphocytic leukemia (CLL) and cytotoxic CD8<jats:sup>+</jats:sup> T cells. To investigate the potential proimmunogenic effects of plasma‐derived reactive oxygen species, cytotoxic T cells were isolated from CLL patients and healthy volunteers. Extensive cold plasma treatment reduced T‐cell metabolic activity and viability in both diseased and healthy groups. Plasma treatment of cocultures, but not CD8<jats:sup>+</jats:sup> T‐cell monocultures, spurred cytotoxic T‐cell proliferation, possibly due to plasma‐enhanced CLL antigen display and plasma‐mediated modulation of immunoregulatory surface molecules. Further studies are needed to understand the mechanisms and clinical relevance of these findings.","PeriodicalId":20135,"journal":{"name":"Plasma Processes and Polymers","volume":"5 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141546984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative study of CF4 + X + He (X = C4F8 or C4H2F6) plasmas for high aspect ratio etching of SiO2 with ACL mask 使用 ACL 掩膜对 CF4 + X + He（X = C4F8 或 C4H2F6）等离子体进行高纵横比二氧化硅蚀刻的比较研究
IF 3.5 3区 物理与天体物理
Plasma Processes and Polymers Pub Date : 2024-07-03 DOI: 10.1002/ppap.202400046
Gilyoung Choi, Alexander Efremov, Kwang‐Ho Kwon
{"title":"Comparative study of CF4 + X + He (X = C4F8 or C4H2F6) plasmas for high aspect ratio etching of SiO2 with ACL mask","authors":"Gilyoung Choi, Alexander Efremov, Kwang‐Ho Kwon","doi":"10.1002/ppap.202400046","DOIUrl":"https://doi.org/10.1002/ppap.202400046","url":null,"abstract":"This work compared C<jats:sub>4</jats:sub>F<jats:sub>8</jats:sub> and C<jats:sub>4</jats:sub>H<jats:sub>2</jats:sub>F<jats:sub>6</jats:sub> gases (as third components in CF<jats:sub>4</jats:sub> + He gas mixture) for the high aspect ratio etching of SiO<jats:sub>2</jats:sub> through the amorphous carbon layer (ACL) mask. The research scheme included the study of gas‐phase plasma characteristics, etching kinetics, and etching profiles. It was found that CF4 + C4F8 + He and CF4 + C4H2F6 + He gas mixtures are featured by quite close plasma parameters, the kinetics of electron‐impact processes, and ion bombardment intensities. At the same, the use of C<jats:sub>4</jats:sub>H<jats:sub>2</jats:sub>F<jats:sub>6</jats:sub> provides a bit lower F atom density together with a bit higher polymerizing ability. All these factors cause lower absolute etching rates for both SiO<jats:sub>2</jats:sub> and ACL but provide better SiO<jats:sub>2</jats:sub>/ACL/ACL selectivity and profile features.","PeriodicalId":20135,"journal":{"name":"Plasma Processes and Polymers","volume":"39 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141546987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multifunctional surface treatment of boron nitride nanotube‐coated polyimide films with atmospheric‐pressure cold plasma 利用常压冷等离子体对氮化硼纳米管涂层聚酰亚胺薄膜进行多功能表面处理
IF 3.5 3区 物理与天体物理
Plasma Processes and Polymers Pub Date : 2024-07-02 DOI: 10.1002/ppap.202400031
Ha Young Choi, Seong Chan Kang, Sang Jun Park, Hee Il Yoo, Sang‐Woo Jeon, Tae‐Hwan Kim, Se Youn Moon
{"title":"Multifunctional surface treatment of boron nitride nanotube‐coated polyimide films with atmospheric‐pressure cold plasma","authors":"Ha Young Choi, Seong Chan Kang, Sang Jun Park, Hee Il Yoo, Sang‐Woo Jeon, Tae‐Hwan Kim, Se Youn Moon","doi":"10.1002/ppap.202400031","DOIUrl":"https://doi.org/10.1002/ppap.202400031","url":null,"abstract":"Polyimide (PI) surfaces coated with and without boron nitride nanotubes (BNNTs) were treated using an atmospheric‐pressure cold plasma in open air. This treatment increased the surface wettability of the PI, measured by a decrease in water contact angle from 68° to 16°, resulting in a more uniform BNNT coating and improved surface adhesion. The plasma treatment of the BNNT‐coated PI surfaces also effectively removed residual polymer surfactants used for BNNT dispersion in water, without causing any thermal damage due to the low plasma and PI's surface temperatures of 350 and 300 K, respectively. The reactive oxygen species in the plasma, such as hydroxyl molecules and oxygen atoms, played an important role in these processes. Atmospheric‐pressure plasma can be employed in various applications in which thermally weak polymer‐based substrates are coated with BNNTs.","PeriodicalId":20135,"journal":{"name":"Plasma Processes and Polymers","volume":"41 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141503507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modulation of programmed death‐ligand 1 expression to augment sensitivity to atezolizumab in breast cancer cells through nonthermal air gas plasma 通过非热气等离子体调节程序性死亡配体 1 的表达，提高乳腺癌细胞对阿特珠单抗的敏感性
IF 3.5 3区 物理与天体物理
Plasma Processes and Polymers Pub Date : 2024-07-01 DOI: 10.1002/ppap.202400072
Shweta B. Borkar, Paritosh Patel, Manorma Negi, Tirtha Raj Acharya, Neha Kaushik, Eun Ha Choi, Nagendra K. Kaushik
{"title":"Modulation of programmed death‐ligand 1 expression to augment sensitivity to atezolizumab in breast cancer cells through nonthermal air gas plasma","authors":"Shweta B. Borkar, Paritosh Patel, Manorma Negi, Tirtha Raj Acharya, Neha Kaushik, Eun Ha Choi, Nagendra K. Kaushik","doi":"10.1002/ppap.202400072","DOIUrl":"https://doi.org/10.1002/ppap.202400072","url":null,"abstract":"The aggressiveness and limited treatment options make triple‐negative breast cancer (TNBC) a challenging condition to treat. Immune checkpoint blockade therapy, explicitly targeting the programmed death‐ligand 1 (PD‐L1) pathway, is a promising therapeutic approach. However, the effectiveness of PD‐L1 inhibitors like atezolizumab depends on adequate PD‐L1 expression within cancer cells. To this end, this study used nonthermal plasma (NTP) to modulate PD‐L1 in TNBC cells. The current investigation revealed that NTP treatment leads to an upregulation of PD‐L1; this might increase the availability of PD‐L1 to PD‐L1 inhibitors. These findings suggest that shortly NTP could be used as an adjunctive treatment to immunotherapy in TNBC cells.","PeriodicalId":20135,"journal":{"name":"Plasma Processes and Polymers","volume":"31 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141503508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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