{"title":"Effects of cold atmospheric plasma‐treated medium on HaCaT and HUVEC cells in vitro","authors":"Mingyan Chen, Junjin Chen, Tian Xie, Zheng Chen, Guimin Xu","doi":"10.1002/ppap.202400132","DOIUrl":"https://doi.org/10.1002/ppap.202400132","url":null,"abstract":"Cold atmospheric plasma (CAP) is an emerging technology that can generate various reactive oxygen and nitrogen species (RONS) at room temperature and shows promising applications for skin wound healing. The effects of plasma‐treated medium (PTM) promoting cell proliferation have been verified, but the biological mechanisms involved are not well known. This study aims to assess the proliferation effect and mechanism induced by PTM on human keratinocyte cells (HaCaT) and human umbilical vein endothelial cells (HUVEC) in vitro. The results showed that the concentrations of H<jats:sub>2</jats:sub>O<jats:sub>2</jats:sub> and NO<jats:sub>2</jats:sub><jats:sup>−</jats:sup> inside PTM increased in a time‐dependent manner as the atmospheric pressure plasma jet (APPJ) treatment time was prolonged. The biological outcomes were determined by cell counting kit, wound healing assay, flow cytometry, enzyme‐linked immunosorbent assay (ELISA), and western blot analysis. The cell viability and motility assays indicated that appropriate plasma conditions of short treatment time (15s‐, 30s‐ and 45s‐PTM) could promote cell proliferation, while long treatment time would inhibit cell proliferation (60s‐PTM). With an appropriate time of PTM treatment, the secretion of vascular endothelial growth factor‐α (VEGF‐α) and transforming growth factor alpha (TGF‐α) was promoted and the extracellular signal‐regulated kinase/serine‐threonine protein kinase pathways were activated, which induced HaCaT and HUVEC cell proliferation eventually. These behaviors of cells were mainly related to the enhancement of intracellular reactive oxygen species levels. These findings established a theoretical foundation for potential clinical applications of PTM in wound healing.","PeriodicalId":20135,"journal":{"name":"Plasma Processes and Polymers","volume":"8 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142188979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Т. S. Batukaev, I. V. Bilera, G. V. Krashevskaya, I. L. Epstein, Yu. A. Lebedev, A. V. Tatarinov, A. Yu. Titov
{"title":"Hydrogen production in microwave discharge in water with barbotage of methane at atmospheric pressure: Experiment and modeling","authors":"Т. S. Batukaev, I. V. Bilera, G. V. Krashevskaya, I. L. Epstein, Yu. A. Lebedev, A. V. Tatarinov, A. Yu. Titov","doi":"10.1002/ppap.202400139","DOIUrl":"https://doi.org/10.1002/ppap.202400139","url":null,"abstract":"Gas chromatography was used to study the products of an atmospheric pressure microwave discharge in water with methane bubbling at incident microwave power ranging between 500 and 650 W and methane flow rate ranging between 25 and 75 mL/min. The main components of products are H<jats:sub>2</jats:sub>, CO, CO<jats:sub>2</jats:sub>, and CH<jats:sub>4</jats:sub>. The concentration of H<jats:sub>2</jats:sub> reaches 75% with the energy consumption for hydrogen formation of 25 L/kWh. A zero‐dimensional self‐consistent nonstationary discharge model, which takes into account the process of quenching of reaction products, was developed to analyze experimental results and study mechanisms of the formation of hydrogen and carbon oxides. Taking into account the quenching of reaction products is an important and necessary part of modeling discharges in liquids.","PeriodicalId":20135,"journal":{"name":"Plasma Processes and Polymers","volume":"13 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142188978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The dynamics and transport of ozone in the gas and liquid phase generated by air surface microdischarge plasma at atmospheric pressure","authors":"Zhiwei Wang, Chen Liu, Chunlei Feng, Cuizhen Wang, Longwei Chen, Hongbin Ding, Xiaoqian Cui","doi":"10.1002/ppap.202400112","DOIUrl":"https://doi.org/10.1002/ppap.202400112","url":null,"abstract":"This contribution focuses on the spatial‐temporal behavior and reactive pathways of O<jats:sub>3</jats:sub> produced by a surface air microdischarge in the gas and liquid phase using ultraviolet absorption spectroscopy. The findings demonstrate that mode transition from ozone to nitrogen oxide over time is observed at a constant input power higher than ~0.60 W/cm<jats:sup>2</jats:sup>. Due to the long‐lived characteristic and ionic wind, the perpendicular distribution of O<jats:sub>3</jats:sub> is almost uniform. The maximum penetration depth is around 5 mm, and the gas–liquid mass transfer efficiency is approximately 0.4‱ at a depth of 1 mm, when the treatment time is 10 min. The mass transfer of O<jats:sub>3</jats:sub> between gas and liquid phases is dominated by the liquid convention induced by ionic wind.","PeriodicalId":20135,"journal":{"name":"Plasma Processes and Polymers","volume":"51 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142188980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammad Reza Lotfi, Pouria Akbar Tehrani, Mohammadreza Khani, Elahe Razaghiha, Erfan Ghasemi, Babak Shokri
{"title":"Physical and chemical diagnostics of cold atmospheric pressure argon plasma jet","authors":"Mohammad Reza Lotfi, Pouria Akbar Tehrani, Mohammadreza Khani, Elahe Razaghiha, Erfan Ghasemi, Babak Shokri","doi":"10.1002/ppap.202400077","DOIUrl":"https://doi.org/10.1002/ppap.202400077","url":null,"abstract":"This article presents an experimental investigation of an argon plasma jet. It examines a commercial argon plasma jet device's physical, chemical, and biological impacts, comparing findings against global standards. The study focuses on electrical features ensuring safety for patients and consumers, finding all leakage current values within established standards. Chemical analysis of emitted gases shows no detectable levels of harmful compounds near treated skin. Optical emission spectroscopy reveals bioactive compounds within the plasma jet. UV radiation emission remains within safety thresholds. Hyperspectral imaging shows temporary increases in skin characteristics posttreatment, reverting to baseline over time. Overall, the study demonstrates the safety and potential of the argon plasma jet in skin treatment.","PeriodicalId":20135,"journal":{"name":"Plasma Processes and Polymers","volume":"7 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142188982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Generation and migration of CO in CO2 DBD glow plasma under Martian pressure","authors":"Qiang Fu, Zifan Ye, Honglin Guo, Zhixin Duan, Jialun Luo, Zhengshi Chang","doi":"10.1002/ppap.202400085","DOIUrl":"https://doi.org/10.1002/ppap.202400085","url":null,"abstract":"Dielectric barrier discharge (DBD) plasma is a potential tool in the field of in situ CO<jats:sub>2</jats:sub> conversion with the low‐pressure environment of Mars. CO is an important intermediate product in the conversion process of CO<jats:sub>2</jats:sub>. Understanding the pathways and dynamics that govern the generation of CO in CO<jats:sub>2</jats:sub> plasmas establishes the foundation for effective regulation. In this work, parallel‐plate DBD structure was employed in our experiment and one‐dimensional fluid simulation model. The findings indicate that CO primarily originates at the boundary of the cathode potential fall region, and it subsequently migrates toward the surface of instantaneous cathode where it accumulates. The thickness of CO‐enriched region is approximately 0.8 mm. During this process, CO migration speed reaches about 2000 m/s. It is worth noting that surface reactions at the instantaneous cathode and anode surfaces contribute only 0.24% to CO generation, in contrast to the predominant influence of impact dissociation reaction between CO<jats:sub>2</jats:sub> and electrons (e + CO<jats:sub>2</jats:sub> → 2e + CO + O<jats:sup>+</jats:sup>) at 53.21%, and two‐body decomposition reaction between O<jats:sup>+</jats:sup> and CO<jats:sub>2</jats:sub> (O<jats:sup>+</jats:sup> + CO<jats:sub>2</jats:sub> → O<jats:sup> +</jats:sup><jats:sub>2</jats:sub> + CO) at 35.88%. Finally, the primary factors influencing the migration of CO from production sites to enrichment regions are determined to be particle collisions and momentum exchange between ions and CO, followed by electro‐hydro dynamics force, while dielectrophoresis forces have minimal effect.","PeriodicalId":20135,"journal":{"name":"Plasma Processes and Polymers","volume":"47 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142189020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yury Gorbanev, Anton Nikiforov, Igor Fedirchyk, Annemie Bogaerts
{"title":"Organic reactions in plasma–liquid systems for environmental applications","authors":"Yury Gorbanev, Anton Nikiforov, Igor Fedirchyk, Annemie Bogaerts","doi":"10.1002/ppap.202400149","DOIUrl":"https://doi.org/10.1002/ppap.202400149","url":null,"abstract":"Plasma–liquid systems are best recognised in biomedicine, where the generation of plasma‐treated water and complex organic‐containing solutions affords biological effects. However, plasma interactions with liquids are more diverse. In this review, we look from the chemical point of view at the three fields of plasma–liquid interaction in which plasma is used to convert organic substrates. In wastewater treatment, plasma decomposes organic substances: the selectivity towards specific products is less crucial than process energy costs. In the conversion of organic liquids for sustainable energy purposes, the carbon and hydrogen selectivity to syngas are important, but these are still destructive reactions yielding small molecules. Finally, we provide a comprehensive plasma application list for synthetic organic chemistry and discuss their mechanisms and limitations.","PeriodicalId":20135,"journal":{"name":"Plasma Processes and Polymers","volume":"8 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142224467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Osama A. Shabaek, Mohammad A. Kher‐Elden, Zakaria M. Abd El‐Fattah, Farouk F. Elakshar, Osama Yassin
{"title":"Theoretical investigation on the influence of H2 ${{rm{H}}}_{2}$ additions on the He + 1% O2 ${{rm{O}}}_{2}$ plasma reactivity for water treatment applications","authors":"Osama A. Shabaek, Mohammad A. Kher‐Elden, Zakaria M. Abd El‐Fattah, Farouk F. Elakshar, Osama Yassin","doi":"10.1002/ppap.202400105","DOIUrl":"https://doi.org/10.1002/ppap.202400105","url":null,"abstract":"Plasma‐based technologies offer environmentally friendly means of effective water purification. Here, we present a discharge system with He + 1% . Tunable amounts of were introduced to control the yield of reactive species. Detailed exploration of the system provides a deeper understanding of some of the fundamental chemical kinetics related to plasma‐based wastewater treatment. A global model was used to investigate the effect of additions on the yield of some important reactive species for advanced oxidation treatment of wastewater. Humidity leakage was considered to simulate the effect of humidified environments. The pathway analysis module provides deeper insight into chemical kinetics. It was concluded that additives can be used in tailoring plasma yield for water treatment applications.","PeriodicalId":20135,"journal":{"name":"Plasma Processes and Polymers","volume":"31 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141931890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Space‐resolved gas temperature of a microwave plasma torch used for hydrogen production via methane pyrolysis","authors":"Simon Kreuznacht, Marc Böke, Achim von Keudell","doi":"10.1002/ppap.202400089","DOIUrl":"https://doi.org/10.1002/ppap.202400089","url":null,"abstract":"Pyrolysis of methane is a promising, new, greenhouse gas‐free production method of hydrogen. Here, we present optical emission spectra of a microwave plasma torch operated in an argon–methane mixture. Detailed spatial resolution is achieved by means of Abel inversion. The emission spectra are dominated by dicarbon Swan bands and black body radiation from carbon nanoparticles. Both spectral features are utilized to estimate the gas temperature. In the center of the plasma, gas temperatures of up to 4300 K are reached with large gradients (500 Kmm<jats:sup>‐1</jats:sup>) in the radial direction. The thermal equilibrium chemistry and the kinetics of methane pyrolysis are analyzed to explain the observed coupling between the local gas temperature and the local emission.","PeriodicalId":20135,"journal":{"name":"Plasma Processes and Polymers","volume":"40 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141968665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}