Photodermatology, photoimmunology & photomedicine最新文献_第3页

Association Between the Atherogenic Index of Plasma and Sunburn: A Nationally Representative Study. 血浆动脉粥样硬化指数与晒伤之间的关系：一项具有全国代表性的研究。

IF 2.7 4区医学

Photodermatology, photoimmunology & photomedicine Pub Date : 2026-05-01 DOI: 10.1111/phpp.70091

Linxia Song, Wenbi Yang, Guangjun Miao, Shuncui Wen, Yuxia Song

{"title":"Association Between the Atherogenic Index of Plasma and Sunburn: A Nationally Representative Study.","authors":"Linxia Song, Wenbi Yang, Guangjun Miao, Shuncui Wen, Yuxia Song","doi":"10.1111/phpp.70091","DOIUrl":"10.1111/phpp.70091","url":null,"abstract":"Background: Research shows that sunburn is related to the inflammatory response caused by lipids. The atherogenic index of plasma (AIP) can evaluate the lipid profile through the interaction of different lipid components. However, whether AIP is related to the risk of sunburn has not been confirmed.Method: The method is to include 11,241 National Health and Nutrition Examination Survey (NHANES) participants, and use multivariate logistic regression analysis to analyze the association between AIP and the risk of sunburn. Further subgroup analyses explored the correlation between AIP and sunburn, supplemented by interaction tests to assess model robustness. Additionally, restrictive cubic sample plots were examined to further investigate the nonlinear relationship between AIP and sunburn.Results: Multivariate logistic regression analysis revealed that individuals with higher AIP indices exhibited a higher prevalence of sunburn. Restricted cubic spline analysis demonstrated a positive linear dose-response relationship between AIP and sunburn. Subgroup analysis and interaction tests indicated that the positive correlation between AIP and sunburn prevalence was consistently observed across different populations (all p > 0.05).Conclusion: There is a positive correlation between AIP and the risk and severity of sunburn. Future research needs to carry out longitudinal studies to determine the causal relationship.","PeriodicalId":20123,"journal":{"name":"Photodermatology, photoimmunology & photomedicine","volume":"42 3","pages":"e70091"},"PeriodicalIF":2.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147634169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Window Tinting: An Underutilized Resource for Photoprotection for Photosensitive and High-Risk Skin Cancer Patients. 窗口着色：光敏性和高风险皮肤癌患者的光保护未充分利用的资源。

IF 2.2 4区医学

Photodermatology, photoimmunology & photomedicine Pub Date : 2026-05-01 DOI: 10.1111/phpp.70095

Nada Hentati, Chandler W Rundle, Bryan T Carroll

引用次数: 0

The Utilization of Optical Coherence Tomography in the Assessment of Melasma Activity and Differential Diagnosis. 光学相干层析成像在黄褐斑活动评估和鉴别诊断中的应用。

IF 2.7 4区医学

Photodermatology, photoimmunology & photomedicine Pub Date : 2026-03-01 DOI: 10.1111/phpp.70082

Xiao Ma, Zhe Li, Jie Liu

{"title":"The Utilization of Optical Coherence Tomography in the Assessment of Melasma Activity and Differential Diagnosis.","authors":"Xiao Ma, Zhe Li, Jie Liu","doi":"10.1111/phpp.70082","DOIUrl":"10.1111/phpp.70082","url":null,"abstract":"Background and objectives: Melasma represents a prevalent facial hyperpigmentation disorder that predominantly affects Asian females. This study aims to assess the applicability of Optical Coherence Tomography (OCT) in the cases of melasma, Hori's nevus, and freckles and to summarize the features of OCT images.Patients and methods: This single-center, evaluator-blinded, observational study was carried out at the Department of Dermatology, Peking Union Medical College Hospital from October 2024 to June 2025. All participants underwent noninvasive dermoscopy, reflectance confocal microscopy, and OCT examinations of lesional and perilesional areas.Results: 47 patients with melasma, 6 patients with Hori's nevus, and 13 patients with freckles were included. 18 patients with melasma (38.3%) were categorized into the active stage, whereas 29 patients with melasma (61.7%) were classified into the stable stage. A disruption of the basement membrane zone exceeding 50% and blood vessel dilation were more frequently observed in the active stage (p < 0.05). In the context of differential diagnosis, a disruption of the basement membrane zone exceeding 50% can be regarded as a differentiating factor among melasma, Hori's nevus, and freckles (p < 0.05).Conclusion: OCT can unveil the characteristic features of different melasma stages and offer crucial information for melasma staging and differential diagnosis.","PeriodicalId":20123,"journal":{"name":"Photodermatology, photoimmunology & photomedicine","volume":"42 2","pages":"e70082"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147318121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effectiveness of Home-Based Phototherapy in Vitiligo: A Systematic Review and Meta-Analysis. 家庭光疗治疗白癜风的有效性：一项系统综述和meta分析。

IF 2.7 4区医学

Photodermatology, photoimmunology & photomedicine Pub Date : 2026-03-01 DOI: 10.1111/phpp.70079

Firdavis Xireaili, Hieu Ha, Zhao Feng Liu, Lawrence Lin, Michelle Min Hsiao, Adrian Mar, Christopher Chew

{"title":"The Effectiveness of Home-Based Phototherapy in Vitiligo: A Systematic Review and Meta-Analysis.","authors":"Firdavis Xireaili, Hieu Ha, Zhao Feng Liu, Lawrence Lin, Michelle Min Hsiao, Adrian Mar, Christopher Chew","doi":"10.1111/phpp.70079","DOIUrl":"10.1111/phpp.70079","url":null,"abstract":"Background: Phototherapy with narrowband ultraviolet B (UVB) is an effective treatment for vitiligo. However, it requires frequent in-office visits. Self-administered home-based UVB (HBUVB) therapy with a handheld or panel device is an alternative that has received limited research attention. The purpose of this systematic review and meta-analysis is to evaluate the effectiveness and safety of HBUVB in the treatment of vitiligo compared to in-office UVB (IOUVB).Methods: Searches were conducted on Medline, Cochrane and Embase from inception until 4th of August, 2024. Studies with primary data of patients being treated with a hand-held UVB device were included in this study. Efficacy as measured in number of patients achieving > 50% or > 75% repigmentation was the primary study outcome. Secondary outcomes analyzed were cost, adverse events and adherence.Results: Eighteen studies were included with a total of 1341 vitiligo patients. Of these, four studies (148 HBUVB and 143 IOUVB) could be used for the meta-analysis. HBUVB was not inferior to IOUVB at achieving > 50% (OR 1.04, 95% CI 0.58-1.87) and > 75% repigmentation (OR 1.26, 95% CI 0.65-2.42). Home-based UVB was not associated with an increase in risk for either erythema or burning sensations when compared to IOUVB. There was a 14% lower rate of discontinuation amongst patients using HBUVB.Conclusions and significance/impact: Home-based UVB therapy is not inferior to in-office UVB therapy in efficacy or rate of adverse events and demonstrates favourable treatment adherence. This meta-analysis provides evidence supporting HBUVB as a safe and effective alternative to IOUVB in patients with vitiligo.Trial registration: PROSPERO registration number: (CRD42023478123).","PeriodicalId":20123,"journal":{"name":"Photodermatology, photoimmunology & photomedicine","volume":"42 2","pages":"e70079"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12972856/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147390590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Traumatic Scars: Evaluation of the Best Timing for Early Intervention With Fractional CO₂ Laser Using Optical Coherence Tomography. 创伤性疤痕：利用光学相干断层扫描评价分数CO2激光早期干预的最佳时机。

IF 2.7 4区医学

Photodermatology, photoimmunology & photomedicine Pub Date : 2026-03-01 DOI: 10.1111/phpp.70071

Samia Mohamed Esmat, Mohamed Mahmoud Khafagy, Bothaina Ashraf Mostafa, Marwa Ahmed Amer

{"title":"Traumatic Scars: Evaluation of the Best Timing for Early Intervention With Fractional CO2 Laser Using Optical Coherence Tomography.","authors":"Samia Mohamed Esmat, Mohamed Mahmoud Khafagy, Bothaina Ashraf Mostafa, Marwa Ahmed Amer","doi":"10.1111/phpp.70071","DOIUrl":"10.1111/phpp.70071","url":null,"abstract":"Background: No consensus on when to start fractional CO2 laser in traumatic scars.Objective: Evaluation of three timings of early fractional CO2 laser intervention.Methods: Forty-five patients with facial traumatic scars were randomly divided into three groups. Fractional CO2 laser (three sessions at 4 weeks interval) was started immediately, 2 and 4 weeks after suture removal in groups A, B, and C respectively. The parameters were 25-watt, stack 2, dwell time 800 μs and spacing 1000 μm (5% density). Vancouver Scar Scale (VSS) and optical coherence tomography (OCT) were performed at baseline and 1 month after the last session. Patients reported their satisfaction using 4-point scale.Results: VSS was significantly improved in group A (p value = 0.001), B (p value = 0.001), and C (p value = 0.003) without significant difference between the three groups (p value = 0.258). Pigmentation was significantly improved only in group B (p value = 0.004). OCT revealed significant improvement in epidermal thickness (p value = 0.001) and scar depth (p value = 0.015) in group B.Conclusion: The current work supports early treatment of traumatic scars with fractional CO2 laser, especially 2 weeks after suture removal.","PeriodicalId":20123,"journal":{"name":"Photodermatology, photoimmunology & photomedicine","volume":"42 2","pages":"e70071"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146093765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comment on "Efficacy of Local and Whole-Body Phototherapy for the Treatment of Various Types of Alopecia Areata". 评“局部与全身光疗治疗不同类型斑秃的疗效”。

IF 2.2 4区医学

Photodermatology, photoimmunology & photomedicine Pub Date : 2026-03-01 DOI: 10.1111/phpp.70074

Sijia Li, Liming Wu

引用次数: 0

Correction to "The Efficacy of UVA1 Phototherapy in Psoriasis: Clinical and Histological Aspects". 修正“UVA1光疗对银屑病的疗效：临床和组织学方面”。

IF 2.2 4区医学

Photodermatology, photoimmunology & photomedicine Pub Date : 2026-03-01 DOI: 10.1111/phpp.70083

引用次数: 0

Pulsed Dye Laser Versus Carboxytherapy for the Treatment of Stria Rubra: A Randomized Clinical and Histopathological Study. 脉冲染料激光与羧基疗法治疗红纹：一项随机临床和组织病理学研究。

IF 2.7 4区医学

Photodermatology, photoimmunology & photomedicine Pub Date : 2026-03-01 DOI: 10.1111/phpp.70080

Rana F Hilal, Aya Fahim, Amira Elbendary, Rawan Abumayyala

{"title":"Pulsed Dye Laser Versus Carboxytherapy for the Treatment of Stria Rubra: A Randomized Clinical and Histopathological Study.","authors":"Rana F Hilal, Aya Fahim, Amira Elbendary, Rawan Abumayyala","doi":"10.1111/phpp.70080","DOIUrl":"10.1111/phpp.70080","url":null,"abstract":"Background: Pulsed Dye Laser (PDL) and carboxytherapy target the vascular component of Stria Rubra (SR), followed by a secondary rejuvenating effect.Objective: To compare the efficacy and safety of PDL and carboxytherapy for the treatment of SR.Materials & methods: Twenty patients with SR were included in this study. Each patient received PDL to one randomly selected SR side and carboxytherapy to the other randomly selected SR side. Clinical outcome assessment was done using number of striae and maximum stria width, Vancouver Scar scale (VSS), Erythema index (EI), and histopathological evaluation.Results: Significant improvement in VSS, EI, and histopathological scoring was found after treatment with each modality, whether PDL or carboxytherapy. Comparison between both modalities revealed a non-significant difference between PDL and carboxytherapy as regards VSS, EI, and histopathological scoring change. Histopathological analysis showed a significant increase of collagen and elastic fibres following PDL. Collagen fibres and perpendicular blood vessels increased significantly with carboxytherapy. PIH was encountered following PDL.Conclusion: Both PDL and carboxytherapy are effective for the treatment of SR. PDL is proposed to produce a better outcome as regards improving the texture of SR skin. The risk of pigmentation can be avoided by proper PDL dosage.","PeriodicalId":20123,"journal":{"name":"Photodermatology, photoimmunology & photomedicine","volume":"42 2","pages":"e70080"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147475022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Tinted Sunscreens Protection Against Blue Light Using Transmittance Spectroscopy In Vitro Technique. 利用体外透射光谱技术评价有色防晒霜对蓝光的防护作用。

IF 2.7 4区医学

Photodermatology, photoimmunology & photomedicine Pub Date : 2026-03-01 DOI: 10.1111/phpp.70075

Hawasatu Dumbuya, Katharine Podimatis, Pearl Grimes

{"title":"Evaluation of Tinted Sunscreens Protection Against Blue Light Using Transmittance Spectroscopy In Vitro Technique.","authors":"Hawasatu Dumbuya, Katharine Podimatis, Pearl Grimes","doi":"10.1111/phpp.70075","DOIUrl":"10.1111/phpp.70075","url":null,"abstract":"Background/purpose: Blue light component of visible light spectrum, between the wavelengths of 400-500 nm, specifically from 415 to 455 nm, known as high energy visible (HEV) light, has the greatest photobiological capability, including biological and cutaneous effects. Currently, there are no regulatory guidelines for assessing sunscreens protection against HEV. In this study, we evaluated the HEV-blocking potential of various tinted sunscreens after blue light irradiation using transmittance spectroscopy in vitro technique.Methods: We compared various commercialized tinted sunscreen formulations with SPF levels ranging from 30 to 50, varying UV filter systems, antioxidant types, and iron oxide (FeO) concentrations to account for different shades. HEV (415-455 nm) transmittance for each sunscreen applied on PMMA plates was measured using an OL756 spectroradiometer, before and after blue light irradiation (200 J/cm2) with solar simulator. The HEV-blocking potential percentage of each formulation was calculated before and after irradiation.Results: Overall, sunscreens formulated with FeO and both inorganic filters, zinc oxide and titanium dioxide, demonstrated higher HEV absorbance profiles and blocking potential than darker-tinted organic sunscreens or hybrid, where one inorganic UV filter was present. Consistent with prior reports, the HEV absorbance and blocking potential also correlated with the FeO levels.Conclusion: This study's findings suggest that depending on their formulations, commercialized tinted sunscreens exhibit different levels of blue light protection. Given the relative newness of tinted sunscreens, plus a lack of regulatory standards, there is a need for more research developing methods to measure protection efficacy of products against visible/blue light exposure.","PeriodicalId":20123,"journal":{"name":"Photodermatology, photoimmunology & photomedicine","volume":"42 2","pages":"e70075"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147444601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Efficacy Study of 755 nm Picosecond Laser Combined With 595 nm Pulsed Dye Laser in the Treatment of Port-Wine Stain. 755 nm皮秒激光联合595 nm脉冲染料激光治疗葡萄色斑的临床疗效研究。

IF 2.7 4区医学

Photodermatology, photoimmunology & photomedicine Pub Date : 2026-03-01 DOI: 10.1111/phpp.70077

Jian Huang, Yu Zhang, Zhen Tang, Binping Luo, Lina Tan, Jianyun Lu, Yaping Xiang, Lihua Gao

{"title":"Clinical Efficacy Study of 755 nm Picosecond Laser Combined With 595 nm Pulsed Dye Laser in the Treatment of Port-Wine Stain.","authors":"Jian Huang, Yu Zhang, Zhen Tang, Binping Luo, Lina Tan, Jianyun Lu, Yaping Xiang, Lihua Gao","doi":"10.1111/phpp.70077","DOIUrl":"10.1111/phpp.70077","url":null,"abstract":"Background: Port-wine stain (PWS) is a disfiguring vascular anomaly characterized by persistent cutaneous erythema and progressive tissue hyperplasia. Although pulsed dye laser (PDL) is the first-line treatment and alleviates certain clinical manifestations, incomplete lesion clearance and high recurrence rates persist in some patients, posing significant therapeutic challenges.Objective: To evaluate the efficacy and safety of sequential therapy with a 755 nm picosecond laser (PSL) combined with 595 nm PDL versus 595 nm PDL alone in treating PWS.Methods: Thirty-four patients with PWS were enrolled. Lesions were randomly divided into paired subregions (PDL and PDL + PSL) using a subregional control design. Efficacy was assessed through objective and subjective measures: standardized clinical and dermoscopic images were used to quantify visual scores and clearance rates; reflectance confocal microscopy (RCM) quantitatively analyzed changes in vascular density and diameter; patient satisfaction and adverse reactions were also evaluated.Results: The PSL + PDL group showed significantly greater improvement in visual assessment scores, lesion area clearance, vascular density, vascular diameter, and patient satisfaction compared to the PDL group (all p < 0.05). While no statistically significant difference was observed in adverse event incidence rates between the two treatment modalities (p > 0.05), both regimens exhibited favorable safety profiles.Conclusion: The PSL + PDL regimen shows significantly superior efficacy over PDL alone, thus presenting a promising and advanced therapeutic alternative for PWS treatment.","PeriodicalId":20123,"journal":{"name":"Photodermatology, photoimmunology & photomedicine","volume":"42 2","pages":"e70077"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12976183/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147434449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0