Photodermatology, photoimmunology & photomedicine最新文献_第4页

Report of a case with CARD14‐associated papulosquamous eruptions and multiple skin cancers 一例与 CARD14 相关的丘疹鳞状溃疡和多发性皮肤癌病例的报告

IF 2.6 4区医学

Photodermatology, photoimmunology & photomedicine Pub Date : 2024-04-15 DOI: 10.1111/phpp.12969

Chia‐Jung Hsu, Tsen‐Fang Tsai

引用次数: 0

Effect of photodynamic therapy with 5-aminolevulinic acid and EDTA-2Na against mixed infection of methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa. 5-aminolevulinic acid 和 EDTA-2Na 光动力疗法对耐甲氧西林金黄色葡萄球菌和铜绿假单胞菌混合感染的影响。

IF 2.6 4区医学

Photodermatology, photoimmunology & photomedicine Pub Date : 2024-03-01 DOI: 10.1111/phpp.12959

Rie Teranishi, Toshiyuki Ozawa, Bunpei Katayama, Yu Shimojo, Nobuhisa Ito, Kunio Awazu, Daisuke Tsuruta

{"title":"Effect of photodynamic therapy with 5-aminolevulinic acid and EDTA-2Na against mixed infection of methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa.","authors":"Rie Teranishi, Toshiyuki Ozawa, Bunpei Katayama, Yu Shimojo, Nobuhisa Ito, Kunio Awazu, Daisuke Tsuruta","doi":"10.1111/phpp.12959","DOIUrl":"10.1111/phpp.12959","url":null,"abstract":"Background: The increasing abundance of drug-resistant bacteria is a global threat. Photodynamic therapy is an entirely new, non-invasive method for treating infections caused by antibiotic-resistant strains. We previously described the bactericidal effect of photodynamic therapy on infections caused by a single type of bacterium. We showed that gram-positive and gram-negative bacteria could be killed with 5-aminolevulic acid and 410 nm light, respectively. However, clinically, mixed infections are common and difficult to treat.Objective: We investigated the bactericidal effects of photodynamic therapy on mixed infections of methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa.Methods: We compared bacterial growth with and without photodynamic therapy in vitro. Then, in vivo, we studied mixed infections in a mouse skin ulcer model. We evaluated the rates of ulcer area reduction and transitions to healing in treated and untreated mice. In addition, a comparison was made between PDT and existing topical drugs.Results: We found that photodynamic therapy markedly reduced the growth of both methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa, in culture, and it reduced the skin ulcer areas in mice. PDT was also more effective than existing topical medicines.Conclusion: This study showed that photodynamic therapy had antibacterial effects against a mixed infection of gram-positive and gram-negative bacteria, and it promoted skin ulcer healing. These results suggested that photodynamic therapy could be effective in both single- and mixed-bacterial infections.","PeriodicalId":20123,"journal":{"name":"Photodermatology, photoimmunology & photomedicine","volume":"40 2","pages":"e12959"},"PeriodicalIF":2.6,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140288775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy of transcranial photobiomodulation in the treatment for major depressive disorder: A TMS-EEG and pilot study. 经颅光生物调制治疗重度抑郁症的疗效：TMS-EEG和试验研究。

IF 2.6 4区医学

Photodermatology, photoimmunology & photomedicine Pub Date : 2024-03-01 DOI: 10.1111/phpp.12957

Wensi Hao, Xiaona Dai, Min Wei, Siran Li, Mao Peng, Qing Xue, Hua Lin, Huicong Wang, Penghui Song, Yuping Wang

{"title":"Efficacy of transcranial photobiomodulation in the treatment for major depressive disorder: A TMS-EEG and pilot study.","authors":"Wensi Hao, Xiaona Dai, Min Wei, Siran Li, Mao Peng, Qing Xue, Hua Lin, Huicong Wang, Penghui Song, Yuping Wang","doi":"10.1111/phpp.12957","DOIUrl":"10.1111/phpp.12957","url":null,"abstract":"Background: Major depressive disorder (MDD) was a prevalent mental condition that may be accompanied by decreased excitability of left frontal pole (FP) and abnormal brain connections. An 820 nm tPBM can induce an increase in stimulated cortical excitability. The purpose of our study was to establish how clinical symptoms and time-varying brain network connectivity of MDD were affected by transcranial photobiomodulation (tPBM).Methods: A total of 11 patients with MDD received 820 nm tPBM targeting the left FP for 14 consecutive days. The severity of symptoms was evaluated by neuropsychological assessments at baseline, after treatment, 4-week and 8-week follow-up; 8-min transcranial magnetic stimulation combined electroencephalography (TMS-EEG) was performed for five healthy controls and five patients with MDD before and after treatment, and time-varying EEG network was analyzed using the adaptive-directed transfer function.Results: All of scales scores in the 11 patients decreased significantly after 14-day tPBM (p < .01) and remained at 8-week follow-up. The time-varying brain network analysis suggested that the brain regions with enhanced connection information outflow in MDD became gradually more similar to healthy controls after treatment.Conclusions: This study showed that tPBM of the left FP could improve symptoms of patients with MDD and normalize the abnormal network connections.","PeriodicalId":20123,"journal":{"name":"Photodermatology, photoimmunology & photomedicine","volume":"40 2","pages":"e12957"},"PeriodicalIF":2.6,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140102206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Whole-body and targeted narrowband ultraviolet B phototherapy effectively stabilize acral vitiligo with negligible repigmentation beyond wrists and ankles: Results from a split-body randomized controlled trial. 全身和定向窄带紫外线 B 光疗可有效稳定痤疮型白癜风，腕部和脚踝以外的色素再形成可忽略不计：分身随机对照试验的结果。

IF 2.6 4区医学

Photodermatology, photoimmunology & photomedicine Pub Date : 2024-03-01 DOI: 10.1111/phpp.12960

Anish Thind, Keshavamurthy Vinay, Hitaishi Mehta, Anuradha Bishnoi, Muthu Sendhil Kumaran, Davinder Parsad

{"title":"Whole-body and targeted narrowband ultraviolet B phototherapy effectively stabilize acral vitiligo with negligible repigmentation beyond wrists and ankles: Results from a split-body randomized controlled trial.","authors":"Anish Thind, Keshavamurthy Vinay, Hitaishi Mehta, Anuradha Bishnoi, Muthu Sendhil Kumaran, Davinder Parsad","doi":"10.1111/phpp.12960","DOIUrl":"10.1111/phpp.12960","url":null,"abstract":"Background: Narrowband ultraviolet B (NB-UVB) phototherapy promotes stability and repigmentation in vitiligo. No studies have compared targeted NB-UVB with whole-body NB-UVB in treatment of acral vitiligo.Objectives: This randomized split-body study compared whole-body NB-UVB with targeted NB-UVB in inducing stability and repigmentation in acral vitiligo.Methods: Thirty-two patients with bilaterally symmetrical acral vitiligo lesions (distal to elbows and knees) were recruited. Patients received whole-body NB-UVB treatment, with one hand and one foot shielded until elbow and knee, followed by targeted NB-UVB treatment on the shielded side. Patients were assessed at 4-week intervals for 24 weeks using Vitiligo Disease Activity (VIDA) score, Vitiligo Skin Activity Score (VSAS), Vitiligo Area Scoring Index (determined through fingertip method, using the method to calculate facial-VASI) and degree of repigmentation.Results: After 12 weeks, 87.5% of patients achieved a VIDA score of 3, with none having active disease at 24 weeks. Over 50% repigmentation was observed in 42.2% and 37.5% of limbs in whole-body and targeted groups, respectively (p = .95). No improvement in F-VASI scores of hands and feet (distal to wrist and ankles) was noted with either modality over the 24-week period.Conclusion: Our study showed comparable repigmentation rates between whole-body and targeted NB-UVB groups. Limited effectiveness of phototherapy in repigmentation of hands and feet underscores an important therapeutic gap.","PeriodicalId":20123,"journal":{"name":"Photodermatology, photoimmunology & photomedicine","volume":"40 2","pages":"e12960"},"PeriodicalIF":2.6,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140120310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of whole blood protoporphyrin and plasma porphyrin in patients on dapsone. 分析服用达哌酮患者的全血原卟啉和血浆卟啉。

IF 2.6 4区医学

Photodermatology, photoimmunology & photomedicine Pub Date : 2024-03-01 DOI: 10.1111/phpp.12962

Amrutha Haridas, Robert S Dawe, Victoria A McGuire

引用次数: 0

Phototherapy for vitiligo: Quality and readability of online health information. 白癜风的光疗：在线健康信息的质量和可读性。

IF 2.6 4区医学

Photodermatology, photoimmunology & photomedicine Pub Date : 2024-03-01 DOI: 10.1111/phpp.12958

Krithika Nayudu, Rhea Malik, Stephanie Sanchez-Melendez, T J Hazen, Mihir K Patil, Vinod E Nambudiri

{"title":"Phototherapy for vitiligo: Quality and readability of online health information.","authors":"Krithika Nayudu, Rhea Malik, Stephanie Sanchez-Melendez, T J Hazen, Mihir K Patil, Vinod E Nambudiri","doi":"10.1111/phpp.12958","DOIUrl":"10.1111/phpp.12958","url":null,"abstract":"Background/purpose: Vitiligo is a depigmenting disorder that affects up to 2% of the population. Due to the relatively high prevalence of this disease and its psychological impact on patients, decisions concerning treatment can be difficult. As patients increasingly seek health information online, the caliber of online health information (OHI) becomes crucial in patients' decisions regarding their care. We aimed to assess the quality and readability of OHI regarding phototherapy in the management of vitiligo.Methods: Similar to previously published studies assessing OHI, we used 5 medical search terms as a proxy for online searches made by patients. Results for each search term were assessed using an enhanced DISCERN analysis, Health On the Net code of conduct (HONcode) accreditation guidelines, and several readability indices. The DISCERN analysis is a validated questionnaire used to assess the quality of OHI, while HONcode accreditation is a marker of site reliability.Results: Of the 500 websites evaluated, 174 were HONcode-accredited (35%). Mean DISCERN scores for all websites were 58.9% and 51.7% for website reliability and treatment sections, respectively. Additionally, 0/130 websites analyzed for readability scored at the NIH-recommended sixth-grade reading level.Conclusion: These analyses shed light on the shortcomings of OHI regarding phototherapy treatment for vitiligo, which could exacerbate disparities for patients who are already at higher risk of worse health outcomes.","PeriodicalId":20123,"journal":{"name":"Photodermatology, photoimmunology & photomedicine","volume":"40 2","pages":"e12958"},"PeriodicalIF":2.6,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140137112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Does the risk of basal cell carcinoma increase in patients with psoriasis under treatment? 接受治疗的银屑病患者罹患基底细胞癌的风险会增加吗？

IF 2.5 4区医学

Photodermatology, photoimmunology & photomedicine Pub Date : 2024-03-01 DOI: 10.1111/phpp.12956

Gülcan Aliye Sevdem, Kucuk Su Ozlem, Yilmaz Nazan, Onsun Nahide

{"title":"Does the risk of basal cell carcinoma increase in patients with psoriasis under treatment?","authors":"Gülcan Aliye Sevdem, Kucuk Su Ozlem, Yilmaz Nazan, Onsun Nahide","doi":"10.1111/phpp.12956","DOIUrl":"10.1111/phpp.12956","url":null,"abstract":"Background: Psoriasis is a common, chronic, inflammatory disease. Although it mainly affects the skin, it has been associated with a large number of comorbidities. In addition to comorbidities such as depression and psoriatic arthritis, it is known that there is an increased prevalence of cancer in psoriasis patients. Skin cancers, particularly squamous cell carcinoma, have been associated with psoriasis. However, basal cell carcinoma data are limited.Methods: 346 psoriasis patients and 306 individuals were selected as the control group. There were no differences between the patient and control groups in terms of age and gender. The mean age of the psoriasis patients was 49.9 ± 15.8 years and the control group was 49.4 ± 13.4 years. Sociodemographic data of the patients were recorded. Pharmacological agents used in the treatment of psoriasis were included in the analysis. Disease severity was assessed by the psoriasis area severity index (PASI). In the physical examination of the patients, biopsies were taken from lesions suspicious for BCC. BCC diagnosis was made by histopathologically.Results: The frequency of BCC was higher in psoriasis patients than in the control group (6.6% vs. 2.9%, p < .001). Advanced age (p < .001), smoking (p = .003), and arthritis (p < .001) were associated with BCC in psoriasis patients. However, there was no relationship between PASI and BCC (p = .142). Among the psoriasis treatments, only UV therapy was associated with BCC (p = .038). The frequency of PUVA (p < .001) and number of PUVA session (p = .010) was higher in psoriasis patients with BCC rather than NB-UVB.Conclusion: The frequency of BCC is increased in psoriasis patients. Psoriasis is associated with an increased risk of BCC, especially when treated with PUVA therapy for a long time.","PeriodicalId":20123,"journal":{"name":"Photodermatology, photoimmunology & photomedicine","volume":"40 2","pages":"e12956"},"PeriodicalIF":2.5,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139973057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The impact of phototherapy on itch intensity and itch-related quality of life amongst different skin diseases, skin phototypes and genders – A prospective study with 102 patients 光疗对不同皮肤病、皮肤光型和性别的瘙痒强度以及与瘙痒相关的生活质量的影响--一项对 102 名患者进行的前瞻性研究

IF 2.6 4区医学

Photodermatology, photoimmunology & photomedicine Pub Date : 2024-01-19 DOI: 10.1111/phpp.12948

Tamara Merkel, Alexander Navarini, Simon Mueller

引用次数: 0

The correlation analysis between alterations of serum vitamin D, IL-33 levels, and clinical improvement after narrow-band UVB treatment in vitiligo patients: A case–control study 白癜风患者血清维生素 D、IL-33 水平变化与窄带紫外线治疗后临床改善之间的相关性分析：病例对照研究

IF 2.6 4区医学

Photodermatology, photoimmunology & photomedicine Pub Date : 2024-01-18 DOI: 10.1111/phpp.12947

Emin Soyer, Berkay Temel, Neslihan Bukan, Canan Yilmaz Demirtas, Ayla Gulekon

引用次数: 0

Photodynamic therapy in periodontitis: A narrative review 牙周炎的光动力疗法：叙述性综述

IF 2.6 4区医学

Photodermatology, photoimmunology & photomedicine Pub Date : 2024-01-17 DOI: 10.1111/phpp.12946

Min Nie, Peipei Zhang, Janak Lal Pathak, Xiaoyu Wang, Yafei Wu, Jingmei Yang, Yuqin Shen

引用次数: 0