Photodermatology, photoimmunology & photomedicine最新文献

{"title":"Attitudes and Behaviors Regarding Sun Exposure of Spain Population.","authors":"Charles Taieb, Alba Crespo-Cruz, Marketa Saint Aroman, Nuria Perez-Cullell, Catherine Baissac, Bruno Halioua, Magdalena de Troya-Martín","doi":"10.1111/phpp.70035","DOIUrl":"10.1111/phpp.70035","url":null,"abstract":"","PeriodicalId":20123,"journal":{"name":"Photodermatology, photoimmunology & photomedicine","volume":"41 4","pages":"e70035"},"PeriodicalIF":2.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12223918/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144554155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Efficacy of Intense Pulsed Light Versus Topical Nicotinamide 4% in Treatment of Acne Vulgaris.","authors":"Hagar Atteya Al-Sharnoby, Reda Hassan Al-Bakary, Samia Othman Nassar, Reem Adel Mahmoud Mesbah","doi":"10.1111/phpp.70025","DOIUrl":"https://doi.org/10.1111/phpp.70025","url":null,"abstract":"<p><strong>Background: </strong>Intense pulsed light (IPL) is a Food and Drug Administration-approved device for the management of several dermatologic disorders, including Acne vulgaris (AV). Nicotinamide, a form of vitamin B3, constitutes a possible therapeutic approach for AV. It has powerful anti-inflammatory benefits without the danger of bacterial resistance or systemic adverse effects.</p><p><strong>Purpose: </strong>To contrast the efficacy and safety of IPL and topical nicotinamide 4% cream in the management of AV.</p><p><strong>Methods: </strong>This comparative work was conducted on 20 participants aged from 18 to 40 years both sexes, with different clinical types of AV. The patients' faces were allocated into two sides: The right side of the face was treated with 4 IPL sessions at two-weeks intervals, while the left side was treated with topical nicotinamide 4% cream twice daily for 2 months. Clinical assessment of acne lesions in all patients was performed before starting treatment and one and 3 months after the last session.</p><p><strong>Results: </strong>A significant enhancement of inflammatory acne lesions existed after treatment with IPL and nicotinamide 4% topical cream. A significant variation existed between the two sides of the face after treatment according to the degree of enhancement, in which the IPL showed better improvement than the nicotinamide 4% cream. Moreover, patients were more satisfied with IPL treatment.</p><p><strong>Conclusions: </strong>IPL seems to be a safe and effective therapy in the management of mild to moderate inflammatory acne and an alternative to other systemic modalities of acne treatment when they are contraindicated.</p>","PeriodicalId":20123,"journal":{"name":"Photodermatology, photoimmunology & photomedicine","volume":"41 4","pages":"e70025"},"PeriodicalIF":2.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144565039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sunscreens: Updates on Sunscreen Filters and Formulations.","authors":"Jasira Ziglar, Tasneem F Mohammad, Yolanda Gilaberte, Henry W Lim","doi":"10.1111/phpp.70026","DOIUrl":"https://doi.org/10.1111/phpp.70026","url":null,"abstract":"<p><strong>Background/purpose: </strong>Sunscreens are a critical component of photoprotection, shielding the skin from the harmful effects of solar radiation. However, current sunscreens have limitations, including insufficient filters with long-wavelength ultraviolet A (UVA) and visible light (VL) coverage. This review briefly discusses the mechanisms of sunscreen filters, newly developed filters that improve broad-spectrum protection, and examines recent advances in sunscreen formulations that enhance efficacy.</p><p><strong>Methods: </strong>A targeted literature review was conducted using databases such as Pubmed to identify recent studies published on advancements in sunscreen filters.</p><p><strong>Results: </strong>Recent developments include novel filters with extended UVA and VL coverage. Additives such as antioxidants and anti-inflammatory agents are also being integrated to bolster skin protection.</p><p><strong>Conclusion: </strong>Although traditional sunscreens have limitations, ongoing innovations in filter development and formulation science are progressively addressing existing gaps in photoprotection.</p>","PeriodicalId":20123,"journal":{"name":"Photodermatology, photoimmunology & photomedicine","volume":"41 3","pages":"e70026"},"PeriodicalIF":2.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144079432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"'Actinic Prurigo': A Phrase Describing Four Different Diseases in Four Different Continents: Systematic Review and Analysis.","authors":"Einapak Boontaveeyuwat, Hiva Fassihi, Robert P E Sarkany","doi":"10.1111/phpp.70018","DOIUrl":"https://doi.org/10.1111/phpp.70018","url":null,"abstract":"<p><strong>Background: </strong>There are no internationally agreed diagnostic criteria for actinic prurigo.</p><p><strong>Objective: </strong>To analyze the clinical features of all patients ever reported in the medical literature with a diagnosis of 'actinic prurigo'.</p><p><strong>Methods: </strong>A systematic literature review of all case reports, case series and retrospective studies published since 1946 about patients given a diagnosis of actinic prurigo. We tested our hypothesis that the patients divide into four clinically distinctive presentations: 'eczematous patch' (EP), 'papular' (P), 'labial' (L) or 'nodular' (N). We divided the papers analysed into these four categories by initial qualitative assessment and then tested our hypothesis of four clinically distinct subtypes by detailed quantitative analysis.</p><p><strong>Results: </strong>Quantitative analysis confirmed the hypothesis that there are four clinically distinct subtypes of actinic prurigo: 'eczematous patch' (EP), 'papular' (P), 'labial' (L) and 'nodular' (N). They differ significantly in clinical features, geographical location, ethnicity of patients and HLA typing. All the subtypes are photosensitive inflammatory dermatoses, with the greatest overlap is between the 'EP' and 'P' subtypes.</p><p><strong>Conclusion: </strong>We propose a new nomenclature for actinic prurigo to include these four subtypes. This improved diagnostic definition should make it easier to define the natural history of this disease and identify effective treatments.</p><p><strong>Prospero: </strong>CRD42018085694.</p>","PeriodicalId":20123,"journal":{"name":"Photodermatology, photoimmunology & photomedicine","volume":"41 3","pages":"e70018"},"PeriodicalIF":2.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144033124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Have We Moved the Needle on Photoprotection Messaging? Insight From Sunburn Trends Using the 2019 Behavioral Risk Factor Surveillance System.","authors":"Maria V Kaltchenko, Anna L Chien","doi":"10.1111/phpp.70027","DOIUrl":"10.1111/phpp.70027","url":null,"abstract":"<p><strong>Background: </strong>Despite decades of public health messaging promoting sun safety and universal sunscreen utilization, sunburn remains prevalent among U.S. adults, posing a significant public health concern due to its links to skin cancer and photoaging.</p><p><strong>Objectives: </strong>This study aims to evaluate self-reported sunburn prevalence and associated risk factors using a nationally representative cross-sectional survey.</p><p><strong>Methods: </strong>We analyzed data from the Centers for Disease Control and Prevention's (CDC's) 2019 Behavioral Risk Factor Surveillance System (BRFSS), a nationally representative cross-sectional survey of the US civilian noninstitutionalized population. Our sample included 15,545 adults aged 18 years and older who had complete data on sunburn and relevant variables. Multivariable logistic regression with adjustment for sampling probabilities was used to examine factors associated with self-reported sunburn in the last 12 months preceding the interview. All statistical analyses were performed using Stata 17.</p><p><strong>Results: </strong>We found that 31.02% of American adults reported sunburn in the past year, with higher rates observed among younger adults, those with higher income and education, and rural residents. Binge drinking was strongly associated with increased sunburn risk. Despite increased sun-protective behaviors such as sunscreen use, seeking shade, and wearing protective clothing, these practices have not significantly reduced sunburn prevalence, particularly among high-risk groups.</p><p><strong>Conclusions: </strong>Our findings suggest that public health campaigns may not sufficiently address the unique needs of certain populations, including young adults, rural residents, and binge drinkers. We recommend tailored interventions, multimodal sun protection strategies, and enhanced use of digital platforms for outreach. Further research is essential to refine these strategies and reduce the public health burden of sunburn and its associated risks.</p>","PeriodicalId":20123,"journal":{"name":"Photodermatology, photoimmunology & photomedicine","volume":"41 3","pages":"e70027"},"PeriodicalIF":2.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144111433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patients With Rosacea Exhibit Lower Minimal Erythema Doses to Both UVA and UVB.","authors":"Rong Wei, Xiaolin Wang, Wenni Lei, Jia Yang, Yanyan Feng","doi":"10.1111/phpp.70019","DOIUrl":"https://doi.org/10.1111/phpp.70019","url":null,"abstract":"<p><strong>Background: </strong>Rosacea, a prevalent chronic inflammatory skin condition primarily affecting the central facial convexities, is categorized into four clinical subtypes: erythematotelangiectatic rosacea (ETR), papulopustular rosacea (PPR), phymatous rosacea (PhR), ocular rosacea (OR). While ultraviolet (UV) radiation is recognized as a risk factor for rosacea, the differential skin sensitivity to UVA and/or UVB between healthy individuals and rosacea patients remains ambiguous.</p><p><strong>Methods: </strong>This study comprised 70 patients diagnosed with rosacea and 100 healthy controls. The minimal erythema doses (MED-UVA and MED-UVB) were ascertained using an SUV-2000 solar UV simulator. A comparative analysis was conducted on the MED-UVA and MED-UVB results between the rosacea patient group and the healthy control group, as well as among rosacea patients with varying clinical subtypes. Furthermore, the correlation between MED values in rosacea patients and factors such as age, skin type, antinuclear antibodies (ANA), and the Clinical Erythema Assessment (CEA) scale was evaluated.</p><p><strong>Results: </strong>In comparison to the healthy control group, the rosacea group demonstrated significantly lower MED-UVA (p < 0.05) and MED-UVB (p ≤ 0.001) values. However, no significant differences were observed in the MED-UVA (p > 0.05) and MED-UVB (p > 0.05) values among patients with varying clinical subtypes of rosacea, specifically between ETR and PPR.</p><p><strong>Conclusion: </strong>Patients diagnosed with rosacea demonstrate a decreased minimal erythema dose to both UVA and UVB, suggesting heightened sensitivity to ultraviolet radiation. Consequently, it is advisable for individuals with rosacea to minimize sun exposure in order to mitigate or prevent exacerbation of the condition.</p>","PeriodicalId":20123,"journal":{"name":"Photodermatology, photoimmunology & photomedicine","volume":"41 3","pages":"e70019"},"PeriodicalIF":2.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144018395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Narrowband Ultraviolet B Therapy on the Skin Barrier in a Murine Model of Dry Skin.","authors":"Sumika Toyama, Yayoi Kamata, Atsuko Kamo, Mitsutoshi Tominaga, Kenji Takamori","doi":"10.1111/phpp.70016","DOIUrl":"https://doi.org/10.1111/phpp.70016","url":null,"abstract":"","PeriodicalId":20123,"journal":{"name":"Photodermatology, photoimmunology & photomedicine","volume":"41 3","pages":"e70016"},"PeriodicalIF":2.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11989187/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143987652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of the Influence of UVR in Cutaneous Melanoma.","authors":"Graeme J Walker, Kiarash Khosrotehrani","doi":"10.1111/phpp.70024","DOIUrl":"10.1111/phpp.70024","url":null,"abstract":"<p><strong>Background: </strong>Although a role for ultraviolet radiation (UVR) in cutaneous malignant melanoma (CMM) development is accepted, there is debate over the magnitude and mechanisms given its association with intermittent but not chronic exposure.</p><p><strong>Objectives: </strong>To assess new ideas and data on the subject, review some debated topics, bringing a molecular view to epidemiological observations.</p><p><strong>Methods: </strong>We reviewed some recent advances in the field of epidemiology and genetics, including phenome-wide association studies, evolutionary genetics related to skin cancer, and mechanisms of UVR-induced DNA adduct formation.</p><p><strong>Results: </strong>High rates of CMM are strongly correlated with light colored skin across the globe. CMM shares risk factors associated with UVR sensitivity with keratinocyte cancer (KC). CMM risk is dominated by MC1R, a gene regulating the proportions of black and red melanin produced. An emerging mutagenic mechanism involves reactive melanin, particularly red pheomelanin, that can itself induce DNA adducts.</p><p><strong>Conclusion: </strong>Demographically, epidemiologically, and mechanistically, pigmentation status is central to CMM risk and a shared genetic susceptibility, comprising several pigmentation genes, between CMM and KCs. In the general population, CMM risk is associated with pale skin and poor tanning ability, mechanistically due to a relative lack of protection against UVR adduct formation, or perhaps via an alternate manner in individuals with abundant pheomelanin. Overall, evidence suggests that UVR exposure impacts CMM risk.</p>","PeriodicalId":20123,"journal":{"name":"Photodermatology, photoimmunology & photomedicine","volume":"41 3","pages":"e70024"},"PeriodicalIF":2.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12093447/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144111415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In Response to \"Photosensitizing Drugs and Risk of Skin Cancer in Women-A Prospective Population-Based Study\".","authors":"Stephen N Birrell","doi":"10.1111/phpp.70021","DOIUrl":"10.1111/phpp.70021","url":null,"abstract":"","PeriodicalId":20123,"journal":{"name":"Photodermatology, photoimmunology & photomedicine","volume":"41 3","pages":"e70021"},"PeriodicalIF":2.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11977301/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysing the Role of Ultraviolet A1 Phototherapy in the Treatment of Primary Cutaneous Lichen Amyloidosis in a Patient With Skin Phototype 1.","authors":"Sam Hughes, Rossel Ahmad, Maryam Kakar, John Ferguson, Ljubomir Novakovic","doi":"10.1111/phpp.70020","DOIUrl":"https://doi.org/10.1111/phpp.70020","url":null,"abstract":"","PeriodicalId":20123,"journal":{"name":"Photodermatology, photoimmunology & photomedicine","volume":"41 3","pages":"e70020"},"PeriodicalIF":2.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144042639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}