Phytochemical Analysis最新文献

{"title":"Correction to \"Bioactive Spirocyclic C-Arylglycosides From the Fungal-Fungal Co-Culture of Pestalotiopsis sp. and Nigrospora sp.\"","authors":"","doi":"10.1002/pca.70072","DOIUrl":"10.1002/pca.70072","url":null,"abstract":"","PeriodicalId":20095,"journal":{"name":"Phytochemical Analysis","volume":" ","pages":"654"},"PeriodicalIF":2.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147646210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality Control of Herbal Medicine Based on Analytical Techniques and Machine Learning: Current Advances and Future Perspectives.","authors":"Yihong Shen, Huan Du, Fenglian Liu, Xiaolin Gou, Yiwen Tao, Xinge Lan, Jing Zhang, Yinghao Yin, Qi Li, Gang Fan","doi":"10.1002/pca.70065","DOIUrl":"10.1002/pca.70065","url":null,"abstract":"<p><strong>Introduction: </strong>This study enhances the quality control (QC) system essential for the modernization and global acceptance of herbal medicines (HMs).</p><p><strong>Objectives: </strong>This review systematically explores the transformative integration of modern analytical technologies (e.g., IR, MS, and NMR) with machine learning (ML) for advancing HMs QC. Focusing on research from the past 10 years, we highlight groundbreaking applications in three pivotal areas: geographical origin tracing, adulteration detection, and species identification of HMs.</p><p><strong>Methods: </strong>A comprehensive review of the literature from the past 10 years was conducted, focusing on geographical origin tracing, adulteration detection, and species identification of HMs.</p><p><strong>Results: </strong>Providing a structured overview of analytical technologies and ML algorithmic principles demonstrates how ML models decode complex, high-dimensional chemical data to establish predictive and holistic quality assessment frameworks that transcend the limitations of single-marker analysis.</p><p><strong>Conclusion: </strong>This synthesis maps the current research landscape and is a foundational reference for guiding future efforts toward standardized, data-driven, and intelligent quality assurance in HMs.</p>","PeriodicalId":20095,"journal":{"name":"Phytochemical Analysis","volume":" ","pages":"488-506"},"PeriodicalIF":2.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147271877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Strategy of Screening Drug Combination From Traditional Chinese Medicine Based on Biomimetic Extracted Substances: Bufei Yishen Formula as a Case.","authors":"Xuemei Xu, Yanqin Qin, Mengxia Yin, Liuyue Yin, Xiaoqian Li, Yan Du, Peng Zhao, Jiansheng Li, Xinguang Liu","doi":"10.1002/pca.70070","DOIUrl":"10.1002/pca.70070","url":null,"abstract":"<p><strong>Introduction: </strong>Traditional Chinese medicine (TCM) comprises complex matrices with largely unidentified constituents, which has resulted in clinical insecurity and difficulty in quality control. Substantial efforts have been made to screen drug combinations to replace TCM formulas; however, these methods fail to consider biotransformation among phytochemicals.</p><p><strong>Objective: </strong>A \"biomimetic extracted substances (BESs)\" based strategy was proposed-which fully considers in vivo processes-to identify anti-chronic obstructive pulmonary disease (COPD) combinations from Bufei Yishen formula (BYF).</p><p><strong>Methods: </strong>BES of each BYF ingredient was prepared via sequential coculture with artificial gastric juice, intestinal fluid, intestinal flora, and liver S9, with the compositions identified by UHPLC-Q Exactive MS. Cytotoxicity and effects on IL-6 secretion were analyzed in LPS-induced macrophages to compare BYF ingredients and their BESs, screening for optimal anti-COPD combinations. Therapeutic effects were evaluated in a smoking-induced rat COPD model.</p><p><strong>Results: </strong>Twenty-six metabolites were identified in the BESs of five BYF ingredients from different metabolic sites. Bionic extraction reduced cytotoxicity and changed the anti-inflammatory efficacy of BYF ingredients. Based on BES activity, nobiletin and icariin showed the highest anti-inflammatory activity. In the COPD model, their combination significantly alleviated lung injury and inflammatory responses. Combined with metabolic analysis, the efficacy of nobiletin may be attributed to its prototype component, whereas icariin may be attributed to its deglycosylated metabolites.</p><p><strong>Conclusion: </strong>BESs more closely mimics the cytotoxicity and bioactivity of TCM after metabolism. Screening based on BES thus improves consistency between in vitro and in vivo results. Using this strategy, nobiletin and icariin were identified as a potentially effective combination within BYF for alleviating COPD.</p>","PeriodicalId":20095,"journal":{"name":"Phytochemical Analysis","volume":" ","pages":"636-653"},"PeriodicalIF":2.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147623379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Selective Deconstruction of Natural Lignocellulose/Eucommia ulmoides Gum Composite by Recyclable Acidic Deep Eutectic Solvents.","authors":"Fangli Huang, Yuchun Xiao, Jian He, Shima Liu, Jie Guo, Ke Song, Xianwu Zhou","doi":"10.1002/pca.70063","DOIUrl":"10.1002/pca.70063","url":null,"abstract":"<p><strong>Introduction: </strong>Eucommia ulmoides biomass is a natural composite comprising E. ulmoides lignocellulose (LC) and E. ulmoides gum (EUG). However, the full utilization of this composite system is hindered by its structural complexity.</p><p><strong>Objectives: </strong>The aim of this study was to identify an optimal acidic deep eutectic solvent (DES) system for the selective deconstruction of the lignocellulose/E. ulmoides gum (LC/EUG) composite and to unlock the application potential of this natural composite.</p><p><strong>Methods: </strong>E. ulmoides Oliver pericarp (EUP) was used as a feedstock in this study, and the composition and structure alterations induced in the LC/EUG system by pretreatment with six acidic choline chloride-based DES formulations were systematically evaluated.</p><p><strong>Results: </strong>Under optimized conditions (ChCl/oxalic acid, solid-to-liquid ratio 1:35, molar ratio 1:2, 110°C, 3 h), delignification and hemicellulose removal reached 88.72% and 85.46%, respectively, with more than 90% cellulose retention. Moreover, the relative content of EUG in the solid substrate increased from 11.81% to 21.26%. The DES still maintained an efficiency of over 70% in removing hemicellulose and lignin even after five recycling cycles, which highlights its good sustainability. In addition, DES pretreatment led to an increase in the crystallinity index (CrI) of cellulose from 56.68% to 63.35%, disruption of the lignin-hemicellulose matrix, and the formation of a highly porous, cellulose-rich surface. The extracted lignin featured low condensation and a high specific surface area, rendering it suitable for synthesizing high-value-added materials and chemicals.</p><p><strong>Conclusion: </strong>This work provides insights into targeted modulation of natural polymer composites in biomass and offers references for green solvents in E. ulmoides valorization.</p>","PeriodicalId":20095,"journal":{"name":"Phytochemical Analysis","volume":" ","pages":"555-571"},"PeriodicalIF":2.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147271923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcriptome Insight Into the Identification of Novel Luteolin 7-O-Glucosyltransferase From Lonicerae Japonicae Flos Under Salt Stress.","authors":"Zhichen Cai, Cuihua Chen, Jingjing Shi, Lisi Zou, Xunhong Liu","doi":"10.1002/pca.70064","DOIUrl":"10.1002/pca.70064","url":null,"abstract":"<p><strong>Introduction: </strong>Salt stress represents a critical abiotic constraint affecting the growth of medicinal plants and secondary metabolite biosynthesis. While glycosylation plays an established role in plant stress adaptation mechanisms, the specific functional contributions of uridine diphosphate glycosyltransferases (UGTs) to salt stress responses remain insufficiently characterized. Cynaroside (luteolin 7-O-glucoside) is a pharmaceutically valuable flavone glycoside demonstrating enhanced accumulation under saline conditions, and the coordinated upregulation of UGTs in salt-stressed Lonicerae Japonicae Flos (LJF) prompted an investigation into specific glycosyltransferases mediating this stress-induced metabolic response.</p><p><strong>Objective: </strong>This study aims to identify and functionally characterize the UGTs involved in the biosynthesis of cynaroside in LJF under salt stress.</p><p><strong>Methods: </strong>The transcriptomes and metabolomes of LJF under salt stress were comprehensively analyzed to identify candidate UGTs. Then, heterologous expression in Escherichia coli, protein purification technology, enzyme catalysis experiments, and molecular docking were conducted to further verify its catalytic activity.</p><p><strong>Results: </strong>A novel glycosyltransferase was identified from LJF. Functional characterization demonstrated the recombinant enzyme's capacity to catalyze luteolin glycosylation, producing cynaroside through regioselective glucose conjugation. Molecular docking simulations revealed stable binding of luteolin to Lj7OGT3's conserved PSPG motif (plant secondary product glycosyltransferase signature domain), providing structural insights into its catalytic mechanism.</p><p><strong>Conclusion: </strong>This study identified the role of Lj7OGT3 in enhancing cynaroside production under salt stress, which further deepened our understanding of stress-responsive secondary metabolism. Simultaneously, expanding the database of plant functional glycosyltransferases. These findings provide a biochemical foundation for engineering stress-resilient medicinal plants and developing biotechnological platforms for optimized production of bioactive glycosides.</p>","PeriodicalId":20095,"journal":{"name":"Phytochemical Analysis","volume":" ","pages":"572-585"},"PeriodicalIF":2.6,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146166308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive Degradation Analysis of Swertiamarin: Stability-Indicating Assay and Structure Elucidation of Degradation Products.","authors":"Bhakti Nanaware, Pranav Shevkar, Venkata Gopal Ede, Ashutosh Goswami, Abhijeet S Kate","doi":"10.1002/pca.70053","DOIUrl":"10.1002/pca.70053","url":null,"abstract":"<p><strong>Introduction: </strong>Swertiamarin (SWE) is a bioactive secoiridoid glycoside derived from the medicinal plant Enicostemma littorale and is a promising candidate for anti-diabetic therapy. However, SWE have shown poor bioavailability and stability concerns.</p><p><strong>Objective: </strong>This study aims to systematically investigate the stability of swertiamarin under controlled stress conditions according to International Council for Harmonisation (ICH) guidelines.</p><p><strong>Materials and methods: </strong>A stability-indicating high-performance liquid chromatography (HPLC) method was developed and validated. Forced degradation of SWE was performed under heat (60°C), oxidative, and hydrolytic (acidic, basic, neutral) stress conditions.</p><p><strong>Results: </strong>SWE underwent rapid degradation under hydrolytic stress, degrading completely within 20 minutes in base and within 2 hours in acid. These stress conditions produced four degradation products namely 5‑hydroxysecologanolic acid, loganic acid, sweritranslactone C, and sweritranslactone B. Overall, SWE was stable at 60°C and significantly degraded under other tested stress conditions such as acidic, basic, aqueous neutral and oxidative conditions.</p><p><strong>Conclusion: </strong>The findings highlight the instability of SWE under stress environments and underscore the necessity of protective formulation strategies and controlled storage conditions to ensure its pharmaceutical efficacy in therapeutic applications.</p>","PeriodicalId":20095,"journal":{"name":"Phytochemical Analysis","volume":" ","pages":"473-482"},"PeriodicalIF":2.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146166356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling the Effects of Drying Techniques on Phytochemical Profiles and Quality Attributes of Eriobotryae Folium.","authors":"Ming-Jin Zhang, Ya-Ling An, Fei Huang, Bei-Bei Ding, Hao Wang, Jia-Wei Wang, Zhen-Wei Li, Xiao-Kang Liu, Dai-di Zhang, De-An Guo","doi":"10.1002/pca.70051","DOIUrl":"10.1002/pca.70051","url":null,"abstract":"<p><strong>Introduction: </strong>Drying is a thermodynamic process involving moisture phase transition and migration, crucial for extending the shelf life of traditional Chinese medicinal materials and reducing postharvest degradation. Eriobotryae folium (EF), the dried leaf of Eriobotrya japonica (Thunb.) Lindl. (Rosaceae), is valued for its medicinal and functional food applications. The retention of its bioactive compounds is strongly influenced by drying methods.</p><p><strong>Objectives: </strong>In this study, the effects of shade drying, hot air-drying (50°C, 75°C, 100°C), microwave drying, and vacuum freeze-drying on the chemical composition and antioxidant activity of EF were systematically evaluated.</p><p><strong>Materials and methods: </strong>Using fingerprint profiling and multivariate statistical analysis, chlorogenic acid, cryptochlorogenic acid, and neochlorogenic acid (CGAs) were identified as key differential components. Spectrum-effect relationship analysis, based on Pearson product-moment correlation analysis (PPMC) and gray relational analysis (GRA), confirmed these three compounds as not only distinguishing markers under different drying conditions but also major bioactive constituents contributing to EF's therapeutic effects. Thus, they are proposed as potential quality markers. A reliable quantitative method was developed for their determination, combined with final moisture content and visual assessment of appearance, to analyze which drying method yielded samples with the best overall quality.</p><p><strong>Results: </strong>CGAs were confirmed as key differential components. Spectrum-effect relationship analysis confirmed these three compounds as distinguishing markers and major bioactive constituents. Microwave-dried samples exhibited the best overall quality.</p><p><strong>Conclusion: </strong>This study established an integrated evaluation system-\"fingerprint profiling-spectrum-effect correlation-targeted component quantification\"-providing a practical and scientific approach for EF quality control and offering a reference for standardizing processing of leaf-derived herbal medicines.</p>","PeriodicalId":20095,"journal":{"name":"Phytochemical Analysis","volume":" ","pages":"461-472"},"PeriodicalIF":2.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147356086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Natural Product Modulators of Protein-Protein Interactions: A Comprehensive Review.","authors":"Emadeldin M Kamel, Ahmed A Allam, Hassan A Rudayni, Faris F Aba Alkhayl, Noha A Ahmed, Al Mokhtar Lamsabhi","doi":"10.1002/pca.70054","DOIUrl":"10.1002/pca.70054","url":null,"abstract":"<p><strong>Introduction: </strong>Natural products offer structurally diverse small molecules that modulate protein-protein interactions (PPIs) by disrupting pathogenic complexes or stabilizing beneficial ones, expanding therapeutic opportunities beyond classical enzyme inhibition.</p><p><strong>Objective: </strong>This review synthesizes natural product PPI modulators, emphasizing target coverage, mechanisms of action, reported potency/affinity, structural evidence, and functional outcomes in cellular or organismal models.</p><p><strong>Methods: </strong>We curated published examples of natural products acting as direct PPI inhibitors or indirect modulators and organized them by (i) functional PPI categories-oncogenic complexes (MDM2-p53, BCL-2 family, IAP-caspase), signaling assemblies (Wnt/β-catenin, 14-3-3/adaptor complexes), chaperone/co-chaperone systems (Hsp90 and partners), and immunophilin-mediated interactions (calcineurin-NFAT, mTOR complexes)-and (ii) mechanistic class, including competitive interface blockade, allosteric modulation, covalent modification of one partner, and stabilization via molecular glue or ternary-complex formation. For each class, we summarize representative scaffolds and report binding affinities or IC50/Ki values and structural data when available.</p><p><strong>Results: </strong>Natural products span multiple modes of PPI control and highlight tractable intervention points across diverse proteins. Representative examples include chlorofusin, a fungal metabolite that disrupts p53-MDM2 (IC₅₀ ~ 4.6 μM); (-)-gossypol, a plant polyphenol acting as a BH3 mimetic that binds BCL-xL (K_i ~ 0.5 μM); celastrol, a covalent triterpenoid that impairs the Hsp90-Cdc37 complex; and cyclosporin A, FK506, and rapamycin, which form ternary complexes to reprogram immunophilin PPIs.</p><p><strong>Conclusion: </strong>Collectively, these modulators demonstrate PPI druggability and provide chemical probes and lead scaffolds for therapeutic development in cancer, neurodegeneration, infectious disease, and immune disorders.</p>","PeriodicalId":20095,"journal":{"name":"Phytochemical Analysis","volume":" ","pages":"375-390"},"PeriodicalIF":2.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146166305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Discovery and Absolute Quantification of Water-Soluble Signature Peptides via LC-MS/MS Based on Proteomics for Quality Evaluation of Goat Horn.","authors":"Baihao Lao, Jingxian Zhang, Jian Sun, Heng Zhou, Hong Yu, Yingying Ran, Fan Huang, Yingying Shen, Xianxian Li, Xiuhong Mao, Shen Ji, Qing Hu","doi":"10.1002/pca.70049","DOIUrl":"10.1002/pca.70049","url":null,"abstract":"<p><strong>Introduction: </strong>Goat horn is a primary substitute for the endangered Saiga antelope horn in traditional medicines. Current quality control (QC) methods lack specificity to effectively detect economically motivated adulteration with horns from other Bovidae species.</p><p><strong>Objective: </strong>This study is aimed at discovering the species-specific peptides and to develop a reliable mass spectrometry-based method for authenticating goat horn and quantifying its signature peptides.</p><p><strong>Methods: </strong>A label-free proteomics strategy was employed to characterize the tryptic digests across five Bovidae species: goat horn (originated from Capra hircus), sheep horn (Ovis aries), buffalo horn (Bubalus bubalis), cattle horn (Bos taurus), and yak horn (Bos grunniens) on a nanoLC-Orbitrap mass spectrometry and screen signature peptides. A novel ultrasound-assisted simultaneous extraction-enzymolysis (UASEE) method was developed for sample preparation. An absolute quantification for seven goat horn peptides was established on UHPLC-MS/MS. Twenty-two batches of goat horn samples were analyzed.</p><p><strong>Results: </strong>Thirteen signature peptides enabling unambiguous differentiation of five Bovidae species were identified. The UASEE method reduced the sample preparation time from over 24-6 h. The quantification method demonstrated satisfactory linearity (r ≥ 0.997), precision (RSD < 8.2%), repeatability (RSD < 5.8%), stability (RSD < 9.2%), and accuracy (recoveries 84.6%-114.2%, RSD < 13.9%). Based on the quantification results, GHpep 7 (mean 0.224 mg/g) and GHpep 11 (mean 0.137 mg/g) were proposed as the optimal QC markers due to high abundance and minimal batch variability (RSD < 15%).</p><p><strong>Conclusion: </strong>This work provides a platform for signature peptide discovery and absolute quantification using UASEE and LC-MS/MS for quality evaluation of goat horn. It effectively addresses adulteration challenges and establishes a foundation for QC standards of goat horn.</p>","PeriodicalId":20095,"journal":{"name":"Phytochemical Analysis","volume":" ","pages":"432-441"},"PeriodicalIF":2.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145945665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapeutic Potential and Mechanisms of Curcumin in Cardiovascular Diseases: A Comprehensive Review.","authors":"Ahad Nourmohammad, Niloofar Zonoubi, Nima Ghavamikia","doi":"10.1002/pca.70045","DOIUrl":"10.1002/pca.70045","url":null,"abstract":"<p><strong>Background: </strong>Curcumin is recognized for its therapeutic potential in cardiovascular diseases (CVDs), with effects on cardiomyocytes, vascular function, and hypertrophy.</p><p><strong>Objective: </strong>This review aims to evaluate curcumin's therapeutic effects, mechanisms of action, and safety in CVD management.</p><p><strong>Methods: </strong>A comprehensive review of existing literature was conducted, focusing on curcumin's impact on ischemia, hypoxia, myocardial hypertrophy, fibrosis, and endothelial function.</p><p><strong>Results: </strong>Curcumin protects cardiomyocytes, enhances vascular function, and exhibits inconsistent effects on cholesterol accumulation in macrophages.</p><p><strong>Conclusion: </strong>While curcumin shows promise as a complementary agent in CVD management, further research, particularly large-scale clinical trials, is essential to validate its efficacy and safety.</p>","PeriodicalId":20095,"journal":{"name":"Phytochemical Analysis","volume":" ","pages":"348-361"},"PeriodicalIF":2.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146093697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}