Plant Foods for Human Nutrition最新文献_第5页

In Vitro Investigation of the Anti-Hepatocellular Carcinoma Activity of Peptides Derived From Quinoa (Chenopodium quinoa Willd) Bran. 藜麦麸皮肽抗肝细胞癌活性的体外研究。

IF 3.1 2区农林科学

Plant Foods for Human Nutrition Pub Date : 2025-01-06 DOI: 10.1007/s11130-024-01256-w

Jiangying Shi, Cai Bi, Shuhua Shan, Mengyun Zhao, Jiarong Li, Xiaoyan Hao, Nifei Wang, Zhuoyu Li

{"title":"In Vitro Investigation of the Anti-Hepatocellular Carcinoma Activity of Peptides Derived From Quinoa (Chenopodium quinoa Willd) Bran.","authors":"Jiangying Shi, Cai Bi, Shuhua Shan, Mengyun Zhao, Jiarong Li, Xiaoyan Hao, Nifei Wang, Zhuoyu Li","doi":"10.1007/s11130-024-01256-w","DOIUrl":"https://doi.org/10.1007/s11130-024-01256-w","url":null,"abstract":"Hepatocellular carcinoma (HCC) is the most common and highly aggressive tumor in the world. Although immunotherapy, surgical resection, targeted therapy and HCC transplantation could improve the prognosis for HCC patients, the tumor recurrence rate of the tumor remains high due to its insidious and invasive nature. Therefore, the development of new HCC therapeutic agents has become particularly important. Quinoa is abundant in bioactive peptides, proteins, and other functional ingredients that confer various health benefits to humans. Quinoa bran, the outer seed coat of quinoa, like quinoa, has extremely high nutritional value and rich protein content. This study firstly found that hydrolysate from quinoa bran protein (QBPP) exhibited targeting anti-HCC effect on the proliferation of HepG2 and Bel-7402 HCC cells in a concentration dependent manner, without significant toxic side effects on normal human liver cells L02. Further, QBPP exerted anti-HCC effect through mitochondria-mediated apoptosis and inhibition of HCC cells migration. Collectively, QBPP shows potential as a next-generation dietary supplement for the prevention and treatment of HCC.","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"80 1","pages":"28"},"PeriodicalIF":3.1,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142931433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optimization of Eco-Friendly Extraction of Bioactive Compounds from Mentha spicata L. Using Ultrasound-Assisted Extraction Combined with Choline Chloride-Based Deep Eutectic Solvents. 超声波辅助萃取-氯化胆碱型深共晶溶剂萃取薄荷生物活性物质的优化研究。

IF 3.1 2区农林科学

Plant Foods for Human Nutrition Pub Date : 2025-01-06 DOI: 10.1007/s11130-024-01270-y

Aleksandra Szydłowska-Czerniak, Aleksandra Moździerz, Agnieszka Kowaluk, Michał Strzelec, Patrycja Topka, Tomasz Sawicki, Małgorzata Tańska

{"title":"Optimization of Eco-Friendly Extraction of Bioactive Compounds from Mentha spicata L. Using Ultrasound-Assisted Extraction Combined with Choline Chloride-Based Deep Eutectic Solvents.","authors":"Aleksandra Szydłowska-Czerniak, Aleksandra Moździerz, Agnieszka Kowaluk, Michał Strzelec, Patrycja Topka, Tomasz Sawicki, Małgorzata Tańska","doi":"10.1007/s11130-024-01270-y","DOIUrl":"10.1007/s11130-024-01270-y","url":null,"abstract":"Three choline chloride (ChCl)-based deep eutectic solvents (DESs) as a new type of green solvents were used for the ultrasound-assisted extraction (UAE) of bioactive compounds from Mentha spicata L. DES containing ChCl and malonic acid (MalA) was selected as the most promising, providing a more effective extraction of antioxidants from spearmint. Response surface methodology (RSM) and a Box-Behnken design (BBD) with three variables, ChCl:MalA molar ratio, water content (WC) in DES, and extraction time (t), were implemented for optimizing the extraction conditions. The optimal conditions were calculated to maximize the antioxidant capacity (AC) determined by 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), and cupric reducing antioxidant capacity (CUPRAC) assays, total phenolic acids (TPAc), total flavonoid aglycones (TFAgly), and total flavonoid glycosides (TFGly). The phenolic profiles in the obtained extracts were analyzed using ultra-performance liquid chromatography (UPLC), revealing that rosmarinic acid, ellagic acid, rutin, kaempferol, and kaempferol-3-O-rutinoside were predominant in the DES extracts.","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"80 1","pages":"31"},"PeriodicalIF":3.1,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142931558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of Pea Protein Isolate Enrichment on the Nutritional, Functional, and Glycemic Properties of Tarhana. 豌豆分离蛋白富集对豌豆营养、功能和升糖特性的影响。

IF 3.1 2区农林科学

Plant Foods for Human Nutrition Pub Date : 2025-01-06 DOI: 10.1007/s11130-024-01281-9

Aayushi Kadam, Kubra Ozkan, Peifan Du, Hamit Koksel, Osman Sagdic, Filiz Koksel

{"title":"Impact of Pea Protein Isolate Enrichment on the Nutritional, Functional, and Glycemic Properties of Tarhana.","authors":"Aayushi Kadam, Kubra Ozkan, Peifan Du, Hamit Koksel, Osman Sagdic, Filiz Koksel","doi":"10.1007/s11130-024-01281-9","DOIUrl":"https://doi.org/10.1007/s11130-024-01281-9","url":null,"abstract":"Tarhana, a traditional fermented food made from cereal flours, yogurt, vegetables, and spices, is recognized for its rich nutritional value and prolonged shelf life. This study investigated the effect of pea protein isolate (PPI) enrichment on select compositional, physical, techno-functional and nutritional properties of tarhana. Six different formulations were prepared by blending PPI and wheat flour (WF) in varying PPI: WF ratios from 0:100 (control) to 100:0. The protein content of the tarhana samples increased proportionally with the PPI concentration, reaching 76.6% in the PPI: WF of 100:0 PPI tarhana compared to 25.1% in the control tarhana. The total phenolic content (TPC) varied, ranging from 534.1 to 702.9 mg GAE/100 g dry basis (db), with higher values observed in PPI enriched tarhana samples. PPI enrichment significantly (p < 0.05) enhanced the antioxidant capacity, measured by ABTS, DPPH, and FRAP assays. PPI-enriched tarhana powders showed improved levels of key polyphenols, including gallic acid, quercetin and ferulic acid. Pasting profile of the tarhana samples showed a decrease in peak viscosity with increasing PPI, indicating the decrease in starch concentration. In-vitro protein digestibility of tarhana samples improved with PPI incorporation, showing values exceeding 84% for all PPI enriched formulations. The glycemic index (GI) of the tarhana samples decreased with increased PPI levels. Tarhana soups made from PPI: WF of 80:20 and 100:0 showed GI values 50.5 and 42.6, respectively, enabling them to be classified as low-GI foods. This research highlighted the potential of PPI to enhance the nutritional and functional properties of traditional tarhana.","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"80 1","pages":"30"},"PeriodicalIF":3.1,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142931432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Protective Effects of Capsaicinoid Glucoside from Fresh Hot Peppers Against Hydrogen peroxide-induced Oxidative Stress in HepG2 Cells Through-dependent Signaling Pathway. 鲜辣椒辣椒素苷通过依赖信号通路对HepG2细胞过氧化氢氧化应激的保护作用

IF 3.1 2区农林科学

Plant Foods for Human Nutrition Pub Date : 2024-12-30 DOI: 10.1007/s11130-024-01250-2

Abdeen Elkhedir, Alsadig Yahya, Mohammed Mansour, Ali Korin, Amgad Albahi, Ibrahim Khalifa, Sajid Maqsood, Xiaoyun Xu

{"title":"Protective Effects of Capsaicinoid Glucoside from Fresh Hot Peppers Against Hydrogen peroxide-induced Oxidative Stress in HepG2 Cells Through-dependent Signaling Pathway.","authors":"Abdeen Elkhedir, Alsadig Yahya, Mohammed Mansour, Ali Korin, Amgad Albahi, Ibrahim Khalifa, Sajid Maqsood, Xiaoyun Xu","doi":"10.1007/s11130-024-01250-2","DOIUrl":"https://doi.org/10.1007/s11130-024-01250-2","url":null,"abstract":"This study aimed to investigate the protective effect of a novel capsaicinoid glucoside (CG) against H2O2-induced oxidative stress in HepG2 cells and elucidate its underlying molecular mechanism. CG treatment significantly reduced H2O2-induced cell mortality and attenuated the production of lactate dehydrogenase and malondialdehyde in a dose-dependent manner. Moreover, CG drastically reduced the ROS levels 18.7, 37.4, and 43.8% at concentrations of 25, 50, and 100 µg/mL, respectively. while increased glutathione content and catalase activity. Most importantly, in silico analysis revealed that CG effectively interacted with each of TRPV1 and Nrf2 by H-bonds, π-π interactions, and hydrophobic forces without simulation fluctuations over 50 ns. TRP, LYS, THR, LEU, GLN, VAL, ILE, and TYR residues of the tested proteins were all involved in the interaction with CG. These findings suggested that CG could reduce H2O2-induced oxidative stress in HepG2 cells via TRPV1/Nrf2 pathway which could be validated in functional foods/supplements formulations.","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"80 1","pages":"25"},"PeriodicalIF":3.1,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142910154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Health Benefits of Monk Fruit under Traditional Dietary Patterns: Perspective on Immunity and Gut Microbiota Modulatory Functions. 传统饮食模式下罗汉果的健康益处：从免疫和肠道菌群调节功能的角度

IF 3.1 2区农林科学

Plant Foods for Human Nutrition Pub Date : 2024-12-30 DOI: 10.1007/s11130-024-01260-0

Jingru Song, Yulu Wei, Fenglai Lu, Dianpeng Li, Hongwei Liu, Xiaojie Yan, Xiaohua Jiang

{"title":"Health Benefits of Monk Fruit under Traditional Dietary Patterns: Perspective on Immunity and Gut Microbiota Modulatory Functions.","authors":"Jingru Song, Yulu Wei, Fenglai Lu, Dianpeng Li, Hongwei Liu, Xiaojie Yan, Xiaohua Jiang","doi":"10.1007/s11130-024-01260-0","DOIUrl":"10.1007/s11130-024-01260-0","url":null,"abstract":"Monk fruit is the mature fruit of Siraitia grosvenorii (Swingle) C. Jeffrey (SG), which contains mogrosides and various nutrients with diverse benefits as a traditional edible herb. The immunomodulatory effects of the ingredients of monk fruit in daily diets are poorly understood. Monk fruit juice concentrate is a commercial product of monk fruit and in this study, the immune-enhancing activity, immunosuppressive prevention, and gut microbiota modulatory effects of the long-term consumption of its diluent (called SG juice) in daily drinking were investigated in both healthy and cyclophosphamide (CTX)-treated mice. The results indicated that SG juice consumption was beneficial to weight management and improved immunity in mice by enhancing various immune factors. 16S rRNA analysis found that SG juice impacted the diversity and gut microbiota composition with the enrichment of immune-related flora, including Alloprevotella, Bifidobacterium_pseudolongum, Lactobacillus, and Bacteroides_sartorii. Additionally, the daily intake of SG juice exerted preventive effects on immunosuppressive mice with the recovery of reduced body weight and immunoglobulin levels, and restoration of gut microbiota imbalance. These data provide scientific insights into the immunomodulatory effects of monk fruit and foresee its application in functional foods.","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"80 1","pages":"26"},"PeriodicalIF":3.1,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142910144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multitarget Peptides Released by In Vitro Static Gastrointestinal Digestion of an Amaranth Protein Beverage. 苋菜蛋白饮料体外静态胃肠消化释放的多靶点肽。

IF 3.1 2区农林科学

Plant Foods for Human Nutrition Pub Date : 2024-12-30 DOI: 10.1007/s11130-024-01243-1

S E Suárez, A Quiroga, A C Sabbione, M Rodríguez, A E Nardo, J Jardin, A Scilingo, V Tironi, F Speroni, M C Añón

{"title":"Multitarget Peptides Released by In Vitro Static Gastrointestinal Digestion of an Amaranth Protein Beverage.","authors":"S E Suárez, A Quiroga, A C Sabbione, M Rodríguez, A E Nardo, J Jardin, A Scilingo, V Tironi, F Speroni, M C Añón","doi":"10.1007/s11130-024-01243-1","DOIUrl":"https://doi.org/10.1007/s11130-024-01243-1","url":null,"abstract":"Beverages formulated from alternative proteins, such as amaranth, are gaining attraction due to changes in human dietary patterns and environmental concerns like resource use and biodiversity loss. This study focuses on assessing the bioactive peptide release from an amaranth protein beverage. This beverage was subjected to a static simulated gastrointestinal digestion (SGD) protocol to evaluate its bioaccessibility and functional potential. The digests were analyzed for in vitro antihypertensive, antioxidant, and antithrombotic activities. Additionally, digested peptide sequences were identified via LC-MS/MS. The results showed that SGD significantly enhanced the release of bioactive peptides, leading to increased ACE inhibition, antioxidant capacity against ABTS + and AAPH-induced radicals, and antithrombotic effects in clotting assays. LC-MS/MS analysis identified 31 peptides in the digests, ranging from 9 to 21 amino acids, associated with various bioactivities. These findings highlight amaranth proteins potential as a source of functional peptides with health-promoting properties. Further research must be done to isolate and characterize specific peptides for potential therapeutic applications.","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"80 1","pages":"27"},"PeriodicalIF":3.1,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142910148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nutraceutical Potential of Wild Leafy Vegetables Commonly Consumed by Tribal Communities: Cassia tora (L.) Roxb., Acalypha fruiticosa Forssk. and Talinum portulacifolium (Forssk.) Asch. ex Schweinf. 部落社区常食用的野生叶菜的营养潜力：决明子（L.）Roxb。；果胶树；和Talinum portulacifolium（福斯克）Asch。Schweinf交货。

IF 3.1 2区农林科学

Plant Foods for Human Nutrition Pub Date : 2024-12-30 DOI: 10.1007/s11130-024-01280-w

Sharon Jacob, Saji Gomez, Berin Pathrose, Manju V Sharma, Anu Mary Markose

{"title":"Nutraceutical Potential of Wild Leafy Vegetables Commonly Consumed by Tribal Communities: Cassia tora (L.) Roxb., Acalypha fruiticosa Forssk. and Talinum portulacifolium (Forssk.) Asch. ex Schweinf.","authors":"Sharon Jacob, Saji Gomez, Berin Pathrose, Manju V Sharma, Anu Mary Markose","doi":"10.1007/s11130-024-01280-w","DOIUrl":"https://doi.org/10.1007/s11130-024-01280-w","url":null,"abstract":"Wide variety of consumable leafy vegetables are present in the nature but most of them are neither utilised nor scientifically investigated. Nutraceutical potential of these plants should be studied to enrich our knowledge, thus making them part of balanced diets. In view of this objective, three leafy vegetables were selected viz., Cassia tora (L.) Roxb., Acalypha fruiticosa Forssk. and Talinum portulacifolium (Forssk.) Asch. ex Schweinf. Phytochemical screening of the leaves collected from these plants was done in four solvents which revealed the presence of many secondary metabolites. Estimation of bioactive components revealed that the total phenolics (22.84 mgGAEg-1), flavonoids (4.60 mgQEg-1) and ascorbic acid (37.34 mg100g-1) were accounted highest in C. tora whereas lycopene (12.61 mg100g-1) and β-carotene (13.79 mg100g-1) in C. tora were on par with A. fruiticosa (12.45 mg100g-1 lycopene and 12.51 mg100g-1 β-carotene). Anthocyanin content was highest in T. portulacifolium (23.62 mg100g-1). The antioxidant activity was estimated using three assays and the maximum antioxidant activity was recorded in C. tora with lowest IC50 values of 431.94 µgmL-1, 30.58 µgmL-1 and 107.59 µgmL-1 in DPPH, FRAP and ABTS assays, respectively. Among the three wild edible plants, C. tora recorded the highest concentration of bioactive compounds and antioxidant capacity.","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"80 1","pages":"24"},"PeriodicalIF":3.1,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142910152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Anti-hyperglycemic and Anti-hyperlipidemic Effects of Trigonella foenum-graecum L. Seeds on Fructose-induced Diabetic Wistar Rats. 葫芦巴种子对果糖诱导的糖尿病大鼠的降血糖、降血脂作用。

IF 3.1 2区农林科学

Plant Foods for Human Nutrition Pub Date : 2024-12-30 DOI: 10.1007/s11130-024-01276-6

Ibrahim Hinad, Youssef S'hih, Abdelhalem Mesfioui, Aboubaker Elhessni, Moulay Laarbi Ouahidi

{"title":"The Anti-hyperglycemic and Anti-hyperlipidemic Effects of Trigonella foenum-graecum L. Seeds on Fructose-induced Diabetic Wistar Rats.","authors":"Ibrahim Hinad, Youssef S'hih, Abdelhalem Mesfioui, Aboubaker Elhessni, Moulay Laarbi Ouahidi","doi":"10.1007/s11130-024-01276-6","DOIUrl":"https://doi.org/10.1007/s11130-024-01276-6","url":null,"abstract":"Trigonella foenum-graecum L. (fenugreek) seeds are widely used in the preparation of various meals and in traditional health care to treat various disorders and diseases, especially Diabetes mellitus. This study was conducted to investigate the antihyperglycemic and antihyperlipidemic effects of the fenugreek seed extract on fructose-induced diabetic wistar rats. Indeed, 5 groups of rats were formed; the first and second groups were composed of normal rats treated with distilled water and fenugreek seed extract, respectively. The third, fourth, and fifth groups composed of diabetic rats were administered distilled water, 500 mg/kg of fenugreek seed extract, and 25 µg/kg. bw of a standard antidiabetic drug consecutively for 28 days. The repeated ingestion of fenugreek seed generated a significant rise (p < 0.05) of food and water consumption in diabetic rats as compared to the rats treated with distilled water. Furthermore, fenugreek seed extract caused a remarkable elevation of the body weights of diabetic rats in comparison with other groups. Additionally, chronic treatment of rats with fenugreek seed extract improved fasting blood sugar, total cholesterol and triglycerides levels in diabetic rats. Fenugreek seed extract has significant anti-diabetic activity by reducing the fasting blood sugar and ameliorating the lipid parameters of diabetic rats. However, more studies are required to isolate the phytochemical constituents that possess these activities and elucidate their mechanisms of action.","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"80 1","pages":"23"},"PeriodicalIF":3.1,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142910157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chia Derived Peptides Affecting Bacterial Membrane and DNA: Insights from Staphylococcus aureus and Escherichia coli Studies. 影响细菌膜和DNA的奇亚衍生肽：来自金黄色葡萄球菌和大肠杆菌研究的见解。

IF 3.1 2区农林科学

Plant Foods for Human Nutrition Pub Date : 2024-12-28 DOI: 10.1007/s11130-024-01240-4

Anaí León Madrazo, Patricia Quintana Owen, Gerardo Pérez Mendoza, Maira Rubi Segura Campos

{"title":"Chia Derived Peptides Affecting Bacterial Membrane and DNA: Insights from Staphylococcus aureus and Escherichia coli Studies.","authors":"Anaí León Madrazo, Patricia Quintana Owen, Gerardo Pérez Mendoza, Maira Rubi Segura Campos","doi":"10.1007/s11130-024-01240-4","DOIUrl":"https://doi.org/10.1007/s11130-024-01240-4","url":null,"abstract":"The increasing concern over microbial resistance to conventional antimicrobial agents used in food preservation has led to growing interest in plant-derived antimicrobial peptides (AMPs) as alternative solutions. In this study, the antimicrobial mechanisms of chia seed-derived peptides YACLKVK, KLKKNL, KLLKKYL, and KKLLKI were investigated against Staphylococcus aureus (SA) and Escherichia coli (EC). Fluorometric assays and scanning electron microscopy (SEM) demonstrated that the peptides disrupt bacterial membranes, with propidium iodide (PI) uptake reaching 72.34% in SA, calcein release of 98.27%, and N-phenyl-1-naphthylamine (NPN) uptake of 84.35% in EC. Increased membrane permeabilization was observed at concentrations above 5 mg/mL. SEM results further confirmed significant morphological changes, supporting the observed membrane damage. Additionally, the peptides showed intracellular activity by altering EC DNA mobility, suggesting a secondary antimicrobial mechanism through DNA interaction. These results indicate that the peptides are promising antimicrobials with potential mechanisms beyond membrane disruption, highlighting the need for further research to comprehensively understand their antimicrobial mechanisms.","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"80 1","pages":"22"},"PeriodicalIF":3.1,"publicationDate":"2024-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142896843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Beneficial Impacts of Chokeberry and Tart Cherry Based Dietary Supplements Consumption on Cellulite Reduction. 食用以蔓越莓和酸樱桃为基础的膳食补充剂对减少脂肪团的有益影响。

IF 3.1 2区农林科学

Plant Foods for Human Nutrition Pub Date : 2024-12-28 DOI: 10.1007/s11130-024-01261-z

Katarina Šavikin, Dubravka Bigović, Nemanja Krgović, Nemanja Menković, Slavka Nikolić, Jelena Živković

{"title":"Beneficial Impacts of Chokeberry and Tart Cherry Based Dietary Supplements Consumption on Cellulite Reduction.","authors":"Katarina Šavikin, Dubravka Bigović, Nemanja Krgović, Nemanja Menković, Slavka Nikolić, Jelena Živković","doi":"10.1007/s11130-024-01261-z","DOIUrl":"https://doi.org/10.1007/s11130-024-01261-z","url":null,"abstract":"Cellulite is an aesthetically distressing skin condition occurring in 80-90% of females and manifesting as dimples and depressions, producing an uneven surface to the skin. Our aim was to evaluate the effect of combined oral consumption of two dietary supplements based on chokeberry and tart cherry juices over a period of 32 days on cellulite reduction. Twenty women aged 21-49 with a cellulite grade of 1-2 according to the Nurnberger-Muller scale were participating in the study. Ultrasonography was applied to analyze the skin structure in addition to biochemical and anthropometric parameters, which were measured before starting the treatment and after 32 days. A reduction in the thickness of the dermis with subcutaneous fat tissue, subcutaneous fat tissue alone, epidermis, and dermis with epidermis (15.02, 14.34, 21.98, and 20.94%, respectively) was noticed, while the length of the fascicles was reduced by 35.93%. Out of 20 subjects, 11 (57.9%) had edema of the dermis at the beginning of the study, which was not recorded at the end of the study. Moreover, a statistically significant increase in the tissue doppler (TD) signals was recorded in all subjects treated with two dietary supplements, indicating a better blood supply. Changes in anthropometric and biochemical parameters were not recorded. Creatinine, urea, ALT, and AST values, as indicators of kidney and liver function, remained at normal reference levels, pointing out the product's safety. The positive effect of chokeberry and tart cherry juice-based dietary supplements consumption in cellulite condition could be connected with microcirculation improvements.","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"80 1","pages":"21"},"PeriodicalIF":3.1,"publicationDate":"2024-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142896842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0