{"title":"Correction: Fluidized-Bed Drying-Roasting Process for Developing a Whole Quinoa Snack.","authors":"S M Demarchi, R M Torrez Irigoyen","doi":"10.1007/s11130-026-01473-5","DOIUrl":"10.1007/s11130-026-01473-5","url":null,"abstract":"","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"81 1","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147284810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yazhou Xu, Tao Xiong, Xinyi Kang, Fang Ma, Linli Zhang, Mingwei Zhao, Lu Xue, Mingyong Xie, Qiang Yu
{"title":"Bioactive Substances Characterization in Probiotic-Fermented Guava (Psidium guajava L.) Juice and Systematic Evaluation of its Anti-Hyperglycemic Activity.","authors":"Yazhou Xu, Tao Xiong, Xinyi Kang, Fang Ma, Linli Zhang, Mingwei Zhao, Lu Xue, Mingyong Xie, Qiang Yu","doi":"10.1007/s11130-025-01466-w","DOIUrl":"10.1007/s11130-025-01466-w","url":null,"abstract":"<p><p>The development of natural anti-hyperglycemic agents with minimal side effects is a critical objective in functional food research. This study comprehensively investigated the anti-diabetic potential and bioactive substances in guava juice fermented with Lacticaseibacillus paracasei NCUH012072 (FM). Using an integrated in vitro and metabolomic approach, the anti-hyperglycemic activity was systematically assessed through a series of bioassays (enzyme inhibition, antioxidant capacity, and insulin-resistant cell models), untargeted metabolomics, and bioinformatic and affinity-based validation. The results demonstrated that FM significantly inhibited key carbohydrate-metabolizing enzymes (α-amylase, α-glucosidase) as well as the insulin signaling regulator protein tyrosine phosphatase 1B (PTP1B) (P < 0.05). Additionally, FM exhibited enhanced antioxidant capacity and improved glucose uptake in insulin-resistant HepG2 cells (P < 0.05). Untargeted metabolomics revealed that fermentation modulated 13 pivotal metabolic pathways. Integrated analysis using Spearman correlation and random forest modeling identified key anti-hyperglycemic metabolites, including flavonoids (e.g., liquiritigenin), phenolic acids (e.g., cis-caffeic acid), and redox-active compounds such as (R)-lipoic acid. Affinity ultrafiltration combined with liquid chromatography-mass spectrometry (AF-LC-MS) further characterized quercetin 3-galactoside and resveratrol as potent inhibitors of the target enzymes. This study not only systematically demonstrates the anti-hyperglycemic properties of probiotic-fermented guava juice but also proposes a comprehensive strategy for identifying bioactive compounds in complex food matrices. The findings offer a theoretical basis for developing fermented fruit-based functional foods as dietary strategies in hyperglycemia management.</p>","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"81 1","pages":"22"},"PeriodicalIF":3.6,"publicationDate":"2026-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146220751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A First Investigation on Verbascum propontideum Murb.: Comparative Biological Properties, Phytochemical Profile and Mineral Composition.","authors":"Burcu Şahin, Mehlika Alper","doi":"10.1007/s11130-026-01470-8","DOIUrl":"10.1007/s11130-026-01470-8","url":null,"abstract":"","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"81 1","pages":"21"},"PeriodicalIF":3.6,"publicationDate":"2026-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12909325/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146207236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Antiobesity Potential of Selected Latin American Edible Plants: A Review.","authors":"Talía Hernández-Pérez, Octavio Paredes-López","doi":"10.1007/s11130-026-01467-3","DOIUrl":"10.1007/s11130-026-01467-3","url":null,"abstract":"","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"81 1","pages":"18"},"PeriodicalIF":3.6,"publicationDate":"2026-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12886307/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146150248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Castro-Alatorre N C, Vioque J, Girón-Calle J, Jiménez-Martínez C
{"title":"Antiproliferative and Anti-Inflammatory Activities of Encapsulated Opuntia Peel Polyphenols.","authors":"Castro-Alatorre N C, Vioque J, Girón-Calle J, Jiménez-Martínez C","doi":"10.1007/s11130-026-01468-2","DOIUrl":"10.1007/s11130-026-01468-2","url":null,"abstract":"<p><p>A key pathophysiological feature of cancer and many chronic diseases is low-grade persistent inflammation. Given the importance of this condition, there is growing interest in natural products with both antiproliferative and anti-inflammatory properties, such as polyphenols. The antiproliferative and immunomodulatory activities of free and encapsulated polyphenol extracts from six Mexican Opuntia (Cactaceae) species have been determined. Extracts from six Opuntia peel varieties were assessed for antiproliferative activity using Caco2 and THP1 cells, as well as for anti-inflammatory potential through nitric oxide scavenging using RAW 264.7 cells. Both the free and encapsulated polyphenol extracts exhibited antiproliferative and nitric oxide-scavenging activities, although encapsulation greatly enhanced these activities. Results show that the peel from Opuntia fruits, a waste byproduct of little value so far, is a source of bioactive compounds with health-promoting properties. This may represent a revalorization of Opuntia crops and wild species that grow in arid and semiarid regions.</p>","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"81 1","pages":"19"},"PeriodicalIF":3.6,"publicationDate":"2026-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146157990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alejandro Cifuentes, Yessica Casales Tlatilpa, Crescencio Bazaldúa Muñoz, Kalina Bermúdez Torres, Irene Perea Arango, Alma Angélica Del Villar-Martínez
{"title":"Comprehensive Phenotypic, Molecular, and Phenolic Analysis of Kalanchoë daigremontiana Hairy Roots.","authors":"Alejandro Cifuentes, Yessica Casales Tlatilpa, Crescencio Bazaldúa Muñoz, Kalina Bermúdez Torres, Irene Perea Arango, Alma Angélica Del Villar-Martínez","doi":"10.1007/s11130-025-01453-1","DOIUrl":"10.1007/s11130-025-01453-1","url":null,"abstract":"<p><p>Hairy root cultures represent a valuable biotechnological tool for the sustainable production of bioactive secondary metabolites. Kalanchoë daigremontiana is known synthesize phenolic compounds and flavonoids associated with antioxidant and health-promoting properties. This study aimed to establish K. daigremontiana hairy root cultures through infection with Rhizobium rhizogenes and to characterize their growth and phenolic profile. Three strains of R. rhizogenes (A4, ATCC 15834 + pTDT, and K599) were evaluated using in vitro-grown plantlets of K. daigremontiana. Root induction and development were monitored, and quantitative image analysis was performed. Next, five hairy root lines were successfully obtained using the ATCC 15,834 + pTDT strain. The rolA, rolB, rolC, rolD, genes and additional T-DNA markers (orf13, orf14 genes), as well as the TDT protein, were detected in all transformed lines. Morphometric evaluation revealed enhanced growth dynamics in lines KdA2, KdB6, and KdB11. Total phenolic and flavonoids contents in hairy roots extracts ranged from 15.60 to 18.37 mg of gallic acid equivalents (GAE)/g extract and 8.77-13.87 mg quercetin equivalents (QE)/g extract, respectively, compared with 278.13 mg GAE/g extract and 32.97 mg QE/g in wild-type roots. Although in hairy root cultures, basal phenolic levels were lower than in wild-type roots, the established cultures provide a genetically stable platform that can be further optimized through elicitation strategies to enhance the production of health-relevant metabolites. These findings underscore the importance of exploring differential accumulation of metabolites in hairy root cultures.</p>","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"81 1","pages":"17"},"PeriodicalIF":3.6,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146125920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria Santamaria, Clara Leguet, Nour Doumani, Patricia Le-Bail, Cristina M Rosell
{"title":"Substitution of Salt with Choline Chloride in Double-Layer Flatbreads: Impact on Technological Properties and Starch Digestibility.","authors":"Maria Santamaria, Clara Leguet, Nour Doumani, Patricia Le-Bail, Cristina M Rosell","doi":"10.1007/s11130-025-01459-9","DOIUrl":"10.1007/s11130-025-01459-9","url":null,"abstract":"<p><p>The association of sodium intake with hypertension has prompted the salt reduction in food processing. However, salt reduction is technologically challenging in process like breadmaking. The aim of this study was to identify the impact of salt reduction on the dough properties, technological characteristics and in vitro digestion on gluten and gluten-free flatbreads. In addition, the inclusion of choline chloride, (E 1001) as salt replacer (25% choline chloride substitution) was explored. Gluten-free dough exhibited higher hardness than gluten dough due to the predominance of gelatinized starch. Salt reduction gluten-free dough presented lower hardness because of the hydrophobicity of the rice proteins. The texture of the flatbreads was not affected by the addition of choline chloride, with control and choline chloride-enriched flatbreads showing similar strength and extensibility. Moreover, gluten-free flatbreads with choline chloride presented lower starch hydrolysis, because of the ionic compound (choline chloride) on starch gelatinization, which increases the viscosity of the system. In conclusion, gluten-free flatbread with choline chloride could represent a potential strategy to decrease the glycemic index and mitigate hypertension in consumers of gluten-free bread.</p>","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"81 1","pages":"16"},"PeriodicalIF":3.6,"publicationDate":"2026-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12835044/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146053458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tianyu Zhang, Jinmei Zhao, Wenxia Dong, Xinyu Wang, Guanghui Hai, Yang Bi, Juan Wei
{"title":"Characterization and Mechanistic Insights Into the Antioxidant and Anti-Aging Components of Extra Virgin Olive Oil.","authors":"Tianyu Zhang, Jinmei Zhao, Wenxia Dong, Xinyu Wang, Guanghui Hai, Yang Bi, Juan Wei","doi":"10.1007/s11130-025-01465-x","DOIUrl":"10.1007/s11130-025-01465-x","url":null,"abstract":"","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"81 1","pages":"15"},"PeriodicalIF":3.6,"publicationDate":"2026-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146030576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hong Chang, Xinru Wang, Donglin Sui, Yi Liu, Xiaodong Xia, Ningbo Qin
{"title":"Sargassum fusiforme-derived Exosome-like Nanoparticles Suppress TLR4/MyD88/NF-κB Pathway to Alleviate Colitis via Modulating Gut Microbiota.","authors":"Hong Chang, Xinru Wang, Donglin Sui, Yi Liu, Xiaodong Xia, Ningbo Qin","doi":"10.1007/s11130-025-01463-z","DOIUrl":"10.1007/s11130-025-01463-z","url":null,"abstract":"<p><p>Plant-derived exosome-like nanoparticles (PELNs) offer both prophylactic and therapeutic potential for ulcerative colitis (UC). Following the successful isolation of Sargassum fusiforme-derived exosome-like nanoparticles (SELNs), this study investigated the protective efficacy of SELNs in mitigating Citrobacter rodentium-induced colitis. SELNs administration exhibited prolonged gut retention and colon-targeting efficacy and significantly alleviated colitis symptoms, including body weight loss, colonic shortening, and histological damage, while promoting tight junction and MUC2 protein expression. SELNs suppressed the TLR4/MyD88/NF-κB cascade, a key inflammatory pathway, resulting in downregulated pro-inflammatory cytokines (TNF-α, IL-6, IL-1β) and upregulated anti-inflammatory cytokines (IL-10, IL-22), coupled with iNOS abrogation. Furthermore, SELNs modulated the gut microbiota compositon, especially increasing the abundance of Muribaculum intestinale, and promoted the production of short-chain fatty acids (SCFAs). Collectively, these findings suggest that SELNs possess significant promise as a functional food ingredient for colitis through intestinal homeostasis modulation and inflammatory pathway regulation. Given their natural source and potent anti‑inflammatory effects, SELNs hold good potential for commercialization as a novel nutraceutical for inflammatory bowel disease intervention.</p>","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"81 1","pages":"13"},"PeriodicalIF":3.6,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145960019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}