Plant Foods for Human Nutrition最新文献

{"title":"The Chemical Composition of Fatty Oil from Oliveria Decumbens Ecotypes and Evaluation of Synergistic Anti-Diabetic and Anti-Obesity Activities.","authors":"Mahbobeh Sadravi, Akbar Karami, Gholamreza Kavoosi, Fatemeh Raouf Fard","doi":"10.1007/s11130-025-01344-5","DOIUrl":"https://doi.org/10.1007/s11130-025-01344-5","url":null,"abstract":"<p><p>Oliveria decumbens Vent. is an aromatic, endemic plant from southern Iran renowned for its numerous health benefits. This study identified fatty acids in eight O. decumbens ecotypes and assessed their antioxidant and amylase activities. Flowers of eight ecotypes of the O. decumbens plant were collected from three provinces of Iran and fatty acids were extracted by in-vitro hexane digestion. Extracts included omega-3, omega-6, hexadecanoic acid, thymol, and carvacrol. The amount of each fatty acid in the Oliveria oil was analyzed by gas chromatography-mass spectrometry. The amounts of omega-3 (7.55-16.02%), omega-6 (7.48-17.42%), and hexadecanoic acid (7.44-18.19%) varied among the different ecotypes. Total phenolic content of the samples was measured. The antioxidant activity of the fatty oils was assessed using the DPPH and ABTS assays. The antioxidant properties of the extracts ranged from 23.16 to 52.7%. The anti-diabetic and anti-obesity evaluation was conducted using α-amylase and lipase enzymes. The IC₅₀ values for Oliveria oil ecotypes were 118.2 ± 6.5-28.13 ± 6.4 µg/ml for the α-amylase enzyme and 40.00 ± 2.5-66.3 ± 2 µg/ml for the lipase enzyme. All Oliveria oil exhibited antioxidant properties; Jahrom, Dakal, Behbahan ecotypes were strong inhibitors of the α-amylase enzyme, and four showed strong to moderate inhibitors. Our in-vitro results show that oils' inhibition abilities roots from their specific chemical components.</p>","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"80 2","pages":"103"},"PeriodicalIF":3.1,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143743061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring Urtica dioica L. as a Promising Alternative Therapy for Obesity-Related Breast Cancer: Insights from Molecular Mechanisms and Bioinformatic Analysis.","authors":"Ayla Eren, Mehmet Varol, Resat Unal, Filiz Altan","doi":"10.1007/s11130-025-01341-8","DOIUrl":"10.1007/s11130-025-01341-8","url":null,"abstract":"<p><p>Obesity and obesity-related breast cancer are major health problems that require alternative treatment strategies. Urtica dioica L. (U. dioica) stands out as a potential therapeutic candidate with its anti-oxidant, anti-cancer and lipid-lowering properties. In this study, the molecular effects of U. dioica were investigated by gene expression analysis and molecular docking methods. U. dioica significantly suppressed the expression of Brca1, Brca2, Fas, Lpl, Dgat1 and Mcp1 genes, resulting in significant changes in lipid metabolism, cancer susceptibility and inflammation. Molecular docking analyses showed that U. dioica components have strong binding affinities with target proteins. In particular, the interactions between Dgat1-Isorhamnetin rutinoside (-10.3 kcal/mol), Fas-Quercetin acetyl rutinoside (-10.3 kcal/mol), Lpl-Apigenin hexoside (-9.2 kcal/mol) and Mcp1-Quercetin acetyl rutinoside (-8.6 kcal/mol) were notable. In vitro and in silico analyses supported each other, revealing the effects of U. dioica in gene expression regulation and the potential for its constituents to interact with proteins. These findings indicate that U. dioica may be a promising alternative therapeutic agent in the treatment of obesity and obesity-related breast cancer and emphasize that its efficacy should be confirmed by clinical trials.</p>","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"80 2","pages":"102"},"PeriodicalIF":3.1,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11953088/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143736027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antioxidant Potential and Bioactive Profiles of Non-Edible Parts of Araucaria angustifolia: Comparative Extraction Methods and Oxidative Stability Evaluation.","authors":"Antonio Cesar Godoy, Milena do Prado Ferreira, Lillian Brito Lins, Sabrina Kerkhoff, Luis Henrique Manosso von Mecheln, Eliana Peliçon Pereira Figueira, Felipe Augusto Gorla, Patricia Daniele da Silva Dos Santos, Dacley Hertes Neu, Oscar de Oliveira Santos","doi":"10.1007/s11130-025-01340-9","DOIUrl":"https://doi.org/10.1007/s11130-025-01340-9","url":null,"abstract":"<p><p>This study explores the antioxidant potential of Araucaria angustifolia, a native Brazilian conifer, focusing on its non-edible parts: trunk bark, seed coat, and spikes. Aqueous, methanolic, and acetonic extracts were prepared and analyzed for antioxidant activity using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and oxygen radical absorbance capacity (ORAC) assays, along with their phenolic compound composition. Methanolic extracts exhibited the strongest antioxidant activity and the highest total phenolic content. Key bioactive compounds identified included gallic acid, 4-hydroxybenzoic acid, caffeic acid, chlorogenic acid, quercetin, and myricetin, with the trunk bark methanolic extract showing the highest concentrations of these compounds. In oxidative stability tests using food matrices, such as homemade buttermilk and soybean oil, the trunk bark methanolic extract extended the induction point to 19:06 h, demonstrating its effectiveness in delaying lipid oxidation. UV-Vis spectroscopy confirmed the presence of bioactive compounds and revealed distinct absorption profiles for each solvent. Principal component analysis further distinguished methanolic extracts for their enrichment in phenolics and flavonoids compared to aqueous and acetonic extracts. The antioxidant capacity of Araucaria angustifolia was comparable to that of other coniferous species, such as pine, reinforcing its potential as a natural source of antioxidants. Methanol proved to be the most effective solvent for extracting bioactive compounds. These findings highlight the potential of Araucaria angustifolia extracts for applications in food preservation, nutraceuticals, pharmaceuticals, and cosmetics, emphasizing the value of its non-edible parts as sustainable sources of natural antioxidants.</p>","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"80 2","pages":"101"},"PeriodicalIF":3.1,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143710880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development, Characterization, and Sensory Acceptability of Typical Brazilian Cheese Bread Premixes Formulated with the Addition of Yacon Potato Flour.","authors":"Rodrigo P Calderan, Vanessa C Zanetti, Mirian C Feiten, Cristiane Fagundes, Eduardo Huber, Samantha L Gonzalez","doi":"10.1007/s11130-025-01339-2","DOIUrl":"https://doi.org/10.1007/s11130-025-01339-2","url":null,"abstract":"<p><p>Yacon potato (Smallanthus sonchifolius) is an Andean wild tuberous root, rich in inulin and fructooligosaccharides, which has not yet become a major cultivar. The increasing demand for safe and convenient products that benefit health, such as functional foods with prebiotic effects, favors the addition of yacon potatoes as flour in processed foods. Thus, this study aimed (i) to develop and characterize two formulations of typical Brazilian cheese bread premixes (CBPs) made of cassava starch added with yacon potato flour (YPF) in different proportions (F1: 2%, and F2: 4%), and (ii) to carry out physical, physicochemical, and sensory analyses on the cheese bread rolls (CBR) developed from CBP and compare to the control formulation (C). Physicochemical analyses were carried out on the YPF, CBP, and CBR, while physical analyses and sensory evaluation were conducted only on CBR. Low moisture (~ 10%) and a_w (0.544-0.588), indicated that CBP do not require refrigeration for transport and storage. Compared to C, F2 CBR showed higher protein (~ 9.4%) and ash (~ 11.6%) contents, but a darker crust color and lower expansion after baking. At the same time, F1 rolls presented physicochemical, color, and most sensory attributes similar to C. Sensory overall acceptance indicated that the CBR would potentially be well accepted on the market, suggesting that the premixes developed are interesting options for consumers looking for healthy and practical foods. Besides promoting food sovereignty and security, the YPF addition to CBP disseminates sustainable development and environmental protection, given that local production is valued and post-harvest losses are reduced.</p>","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"80 2","pages":"99"},"PeriodicalIF":3.1,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143701274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Drying and Bioactive Compounds Extraction of Ripe and Unripe Yerba-Mate Fruits.","authors":"Yuri Eduardo Mendes Gandin, Leda Battestin Quast, Vania Zanella Pinto, Alice Teresa Valduga, Itamar Luís Gonçalves, Ernesto Quast","doi":"10.1007/s11130-025-01342-7","DOIUrl":"10.1007/s11130-025-01342-7","url":null,"abstract":"<p><p>Yerba-mate fruits (Ilex paraguariensis St. Hil), are a source of phytochemicals, but currently have low economic value. This investigation aims to study the changes during the physiological development of the fruits, the mass transfer in the drying process, and the composition of dried fruits and seed oil to upcycle and enhance their economic value and explore new product applications. The drying process was evaluated under: 60, 80 and 110 °C. The development of yerba-mate fruits was monitored over 90 days, showing increases in diameter, mass, and density, along with darkening and color shifts from green to blueish/reddish. Drying times decreased with increasing temperatures, unripe fruits exhibited higher drying rates, and diffusivity coefficient was primarily influenced by temperature. Phytochemical analysis revealed higher saponin levels in unripe fruits and higher anthocyanin content in ripe fruits, with drying temperatures affecting these compounds. Yerba-mate fruit development, drying conditions, and ripening stages impacted their phytochemical profiles and color, providing insights for optimized processing and use.</p>","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"80 2","pages":"100"},"PeriodicalIF":3.1,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification of Bioactive Compounds from Citri Reticulatae Pericarpium and Evaluation of Their Uric Acid-Lowering Activity.","authors":"Jiahao Yuan, Daren Wu, Jiang Liu, Hangran Yang, Yingjian Su, Lingyu Zhang, Shan Lin, Zhixia Zhao, Feng Kang, Jian Li","doi":"10.1007/s11130-025-01337-4","DOIUrl":"https://doi.org/10.1007/s11130-025-01337-4","url":null,"abstract":"<p><p>Citri Reticulatae Pericarpium, the dried and mature peel of wild Citrus reticulata Blanco and its cultivated varieties in the rutaceae family, is an important herb and condiment in Chinese medicine. At present, there are few relevant reports, especially in-depth reports, on the discovery of effective anti-gout natural products from CRP. In this study, four compounds were extracted and characterized from CRP using 70% ethanol, RP-C18, thin layer chromatography (TLC), Sephadex LH-20, high performance liquid chromatography (HPLC), and nuclear magnetic resonance spectroscopy (NMR). Additionally, monomer compounds (apigenin, luteolin) in CRP, along with those isolated from CRP, were investigated through molecular docking and in vitro assessment of their XOD inhibitory activity. Notably, the lowest binding energy (-10.3 kcal/mol) and IC₅₀ value (76.24 µg/mL) denoted a strong inhibitory effect of isosakuranetin with XOD. Further studies showed that isosakuranetin could significantly reduce XOD activity and uric acid levels in xanthine-induced BRL-3A cells. This research elucidates, for the first time, the uric acid-lowering effects of isosakuranetin, offering valuable insights into the potential mechanisms underlying its properties. This study provides a basis for the development of uric acid-lowering products from CRP and in-depth mechanism research of uric acid-lowering compounds.</p>","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"80 2","pages":"97"},"PeriodicalIF":3.1,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pea Peptide Modulates Abnormal Aβ Production in PC12 Cells Induced by Lead Exposure.","authors":"Ning Li, Ningning Cui, Ibrahim A Bakry, Yan Ma, Yongxia Cheng, Guangshan Zhao, Huijie Yang, Lianjun Song, Mingwu Qiao, Dan Hai, Gianni Galaverna, Xianqing Huang","doi":"10.1007/s11130-025-01296-w","DOIUrl":"https://doi.org/10.1007/s11130-025-01296-w","url":null,"abstract":"<p><p>Lead (Pb) exposure poses significant health risks, particularly in neurodegenerative diseases such as Alzheimer's disease (AD). This study investigates the neuroprotective effects of pea peptide (PP4) on PC12 cells exposed to Pb. Using Cell Counting Kit-8 (CCK-8), pretreatment with PP4 at 50 and 200 µM concentrations significantly improved cell viability compared to Pb-only treated cells (P < 0.05), indicating a protective effect. Moreover, Pb exposure led to increased Amyloid Precursor Protein (APP) expression at 10 and 20 µM after 24 h (P < 0.05), while β-site amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) levels were elevated across all concentrations tested (P < 0.05). We established that PP4 can mitigate Pb-induced cytotoxicity and reduce the expression of APP and BACE1 by activating the Phosphoinositide 3-kinase / Protein Kinase (PI3K/AKT) signaling pathway. This study highlights the potential of PP4 as a therapeutic agent in preventing neurotoxic damage associated with lead exposure, suggesting a novel approach for the management of AD.</p>","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"80 2","pages":"98"},"PeriodicalIF":3.1,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Noodles Elaborated with Wheat and Bean Cotyledon Flours Improve Dyslipidemia and Liver Function in Streptozotocin-Induced Diabetic Rats.","authors":"Mayra Denise Herrera, Raquel Karina Cruz-Bravo, Luis Roberto Reveles-Torres, Jesús Adrián López, Megan Montserrat Torres-Aguilar, Mayra Judith García-Robles, Claudia Araceli Reyes-Estrada, Saul Fraire-Velazquez","doi":"10.1007/s11130-025-01333-8","DOIUrl":"https://doi.org/10.1007/s11130-025-01333-8","url":null,"abstract":"<p><p>Type 2 diabetes (T2D) has been intrinsically linked to dyslipidemia. The intake of common beans (Phaseolus vulgaris) is recommended to lower the risk of developing this disease; however, despite its beneficial contribution to health, its value chain has been weakened due to the lack of competitiveness in the market. The aim of this work was to evaluate the capacity of black bean cotyledon flour noodles to modulate lipid profile, atherosclerosis risk and hepatic enzymes levels using diabetic rats. T2D was induced with streptozotocin (30 mg/kg) after a five-week intake of a high fat diet. Metformin-, wheat noodles-, and bean noodles-treated groups were evaluated. During treatment, bean noodles lowered blood cholesterol. After sacrifice, its intake during four months also improved triglycerides and very low density lipoprotein, further related to in vitro inhibition of lipase activity. Moreover, bean noodles-fed rats exhibit decrease hepatic enzymes levels. Results suggest that intake of bean noodles prevent dyslipidemia and improve liver function. Based on the current results, further clinical trials are highly recommended to offer a novel functional food alternative to diabetic patients, and healthy-oriented human consumers.</p>","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"80 2","pages":"96"},"PeriodicalIF":3.1,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143670666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bioactive Blend of Extracts of Molle Leaf and Rica-Rica Flowers To Enhance the Shelf Life of Reduced-Calorie Artisanal Cayote Jam.","authors":"Liliana S Celaya, Luís R Silva, Carmen I Viturro","doi":"10.1007/s11130-025-01334-7","DOIUrl":"https://doi.org/10.1007/s11130-025-01334-7","url":null,"abstract":"<p><p>Extracts from medicinal and aromatic plants and their mixtures have significant potential for use in the food industry due to their antimicrobial and nutraceutical properties. Acantholippia hastulata (Griseb.) (rica-rica) and Schinus areira L. (molle), are medicinal and aromatic plants that grow naturally in the Andean regions of South America. Here, extract blends of molle leaf and rica-rica flowers were screened regarding their antiradical action against DPPH• radical. A selected bioactive blend containing extracts from both species was further evaluated for its in vitro antimicrobial and antioxidant activities, as well as its α-glucosidase inhibitory potential. The blend demonstrated synergistic inhibitory effects against Candida sp., Rhodotorula sp., and α-glucosidase, as well as the ^●NO radical, but showed antagonistic effects against the O₂^●- radical. The main phenolic compounds identified in the synergistic blend include quercetin derivatives (42.6%), isoferulic acid (16.5%) and 3-O-caffeoylquinic acid (9.0%). The bioactive blend was then tested as a preservative in reduced-calorie cayote jam. At a concentration of 800 mg/kg, it effectively inhibited the growth of Candida sp. and Rhodotorula sp., demonstrating efficacy comparable to potassium sorbate. Additionally, the blend successfully preserved the jam during storage, preventing microbial damage.</p>","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"80 2","pages":"95"},"PeriodicalIF":3.1,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unlocking the Potential of Chia Intake in the Management of Metabolic Syndrome and its Risk Conditions: A Narrative Review.","authors":"Mariana Buranelo Egea, Sibele Santos Fernandes","doi":"10.1007/s11130-025-01331-w","DOIUrl":"https://doi.org/10.1007/s11130-025-01331-w","url":null,"abstract":"<p><p>Metabolic syndrome is the occurrence of at least three of the five conditions diabetes, overweight and obesity, triglyceridemia, hypercholesterolemia, and hypertension. Dietary interventions have been one of the first lines of treatment indicated for improving conditions related to metabolic syndrome. The growing interest in plant-based diets and foods with health-promoting qualities has increased significantly. Due to its excellent nutritional and bioactive value, chia seeds have a significant market share, characterized by their high content of proteins, essential fatty acids, fiber, vitamins, minerals, phenolic compounds, and antioxidants. These constituents promote potential positive effects on improving health, especially blood pressure, and reducing oxidative stress and the inflammatory state installed by metabolic syndrome and its risk conditions. However, the ten studies in humans that were reviewed generally showed no effect on anthropometric parameters and biochemical parameters related to glucose and lipid homeostasis. Thus, although chia seeds have a high potential to combat metabolic syndrome, this review found few studies, highlighting a gap in the area and a possible future topic for researchers.</p>","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"80 2","pages":"90"},"PeriodicalIF":3.1,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143658153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}