Plant Foods for Human Nutrition最新文献

{"title":"The Anti-obesity Effects of Lotus (Nelumbo nucifera Gaertn.) Seed Red Skin (Testa) Catechins by Regulating Lipoprotein Lipase Expression and Activity.","authors":"Lingxiao Gong, Shiping Yang, Zishuo Zhang, Hong Xu","doi":"10.1007/s11130-025-01308-9","DOIUrl":"10.1007/s11130-025-01308-9","url":null,"abstract":"<p><p>Lipoprotein lipase (LPL) participates in the development of obesity by regulating triglyceride hydrolysis and fat storage or oxidation. In this study, the anti-obesity effects of lotus seed skin catechins and its mechanisms associated with LPL modulation were demonstrated. In vivo, catechins reduced body weight in high-fat diet-induced obese mice, improved lipid metabolism and antioxidant indices, and modulated LPL activity in adipose and skeletal muscle tissues. The expression of peroxisome proliferator-activated receptor γ (PPARγ) and (angiopoietin-like 4 proteins) ANGPTL4 mRNA and protein was significantly upregulated in epididymal fat depot but downregulated in skeletal muscle tissue. In vitro cell experiments and chromatin immunoprecipitation (ChIP) assays further revealed that the binding sites of PPARγ protein in the ANGPTL4 promoter region were enriched in adipocytes or reduced in skeletal muscle cells in response to catechin treatment. Therefore, lotus seed skin catechins exhibit anti-obesity activity in vivo and in vitro by specifically regulating the activity and expression of LPL in target tissues.</p>","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"80 1","pages":"76"},"PeriodicalIF":3.1,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143476933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the Antioxidant, Antihyperglycemic, and Haemolytic Activities of Hydroalcoholic Extracts of Red and White Pithecellobium dulce Aril at Different Stages of Ripening.","authors":"Nayely Leyva-López, Citlally Rotceh Cebreros-Vázquez, Verónica Zulema Gómez-Saucedo, J Basilio Heredia, Milton Vega-Álvarez, Juventino Iii Colado-Velázquez, Elisa Anali Camacho-Ureta, Silvestre Guadalupe Cázarez-Salazar, Ulises Osuna-Martínez, Selene J Acosta-Cota","doi":"10.1007/s11130-025-01320-z","DOIUrl":"10.1007/s11130-025-01320-z","url":null,"abstract":"<p><p>Pithecellobium dulce Benth. commonly known in Mexico as \"guamúchil\", has been used to treat different diseases due to its pharmacological attributes. P. dulce arils are an important source of metabolites, with antioxidant and antihyperglycemic activities. Scarce studies have evaluated the antioxidant capacity, total phenolic content (TPC), and total anthocyanin content (TAC) in the red aril variety at different maturity stages, to our knowledge, no one has evaluated these properties in the white aril variety. The antihyperglycemic activity at different stages of ripening in P. dulce has not yet been reported. Also, its biosafety in human erythrocytes remains unexplored. This study assessed the in vitro antioxidant, antihyperglycemic, and haemolytic activities of red and white P. dulce aril hydroalcoholic extracts at different stages of ripening. The red mature aril (MRA) hydroalcoholic extracts presented the higher TPC (3103.2 ± 429.5 mgGAE·100 g^-1), flavonoid content (TFC) (98.8 ± 4.7 mgQE·100 g^-1) and TAC (31.4 ± 8.0 mgC3G·100 g^-1). White and immature red arils did not show TAC. The MRA extract showed the highest antioxidant capacity (53,097.2 ± 2,810.4 µmolTE·100 g^-1), and inhibitory activity on α-glucosidase enzyme (IC₅₀ = 53.38 ± 6.63 µg·mL^-1). The immature red aril (IRA) extract showed the highest inhibitory activity versus the α-amylase enzyme (IC₅₀ = 24.10 ± 0.89 µg·mL^-1). All extracts presented non-haemolytic activity (< 2.0% haemolysis). In conclusion, the MRA extract could be a promising constituent in functional foods focused to manage inflammatory diseases or diabetes mellitus type 2, due to its high antioxidant capacity and antihyperglycemic activity. Furthermore, the non-haemolytic activity suggests that the MRA extract is potentially safe for human use, especially in drug formulations or biomedical applications.</p>","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"80 1","pages":"74"},"PeriodicalIF":3.1,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143476904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring Techno-Functional Properties of Brazil Nut (Bertholletia excelsa) Proteins: A Potential Ingredient for the Food Industry.","authors":"Jessica da Silva Matos, Juliana Eloy Granato Costa, Paula Zambe Azevedo, Márcia Cristina Teixeira Ribeiro Vidigal, Jaqueline de Araújo Bezerra, Edgar Aparecido Sanches, Carlos Victor Lamarão, Paulo César Stringheta, Evandro Martins, Pedro Henrique Campelo","doi":"10.1007/s11130-025-01321-y","DOIUrl":"10.1007/s11130-025-01321-y","url":null,"abstract":"<p><p>Brazil nut (Bertholletia excelsa), a high-methionine oilseed, offers a balanced amino acid profile and could serve as a viable protein ingredient in the food industry. This study evaluates the chemical and physicochemical properties of Brazil nut protein concentrate (BNPC), comparing its techno-functional properties to commercial proteins from soy and pea. BNPC exhibited a predominance of β-sheet structures (52%), high hydrophobicity, and excellent oil-holding capacity (~ 3 g oil. g^- 1 of protein), making it suitable for fat-rich food products. However, its foaming capacity and emulsion stability were inferior to soy and pea proteins, indicating the need for pH optimization to enhance these properties. Despite lower water holding capacity and digestibility, BNPC shows significant potential as a sustainable protein source for developing innovative food products, particularly those requiring high oil retention.</p>","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"80 1","pages":"71"},"PeriodicalIF":3.1,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143468753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In silico Screening of Duhaldea nervosa-derived Endogenous Peptides to Predict the Potential Anticancer Mechanisms.","authors":"Yanyan Zhang, Jieyao Ma, Haixia Li, Peizi Liu, Keyi Chen, Shengjun Ma, Wei Cai","doi":"10.1007/s11130-025-01305-y","DOIUrl":"10.1007/s11130-025-01305-y","url":null,"abstract":"<p><p>D. nervosa is a wild perennial herb used in traditional Chinese medicine for treating fractures, rheumatoid arthritis, and digestive disorders. Its primary bioactive components are flavonoids, phenolic acids, and sesquiterpenes. However, bioactive peptides, which exhibit a wide range of biological activities and are commonly found in both animals and plants, have not been reported in D. nervosa to date. To investigate the presence and potential bioactivities of bioactive peptides in D. nervosa, the abundance of endogenous peptides was initially analyzed using a Nano-LC-Q Exactive Plus quadrupole Orbitrap mass spectrometer. Subsequently, bioinformatics screening, computational enzyme hydrolysis, \"target-pathway-disease\" network prediction, molecular docking, and molecular dynamics simulations were performed to evaluate safety, biological activity prediction and investigate the potential anticancer mechanisms of D. nervosa. The results demonstrate that the simulated enzymatic hydrolysates of D. nervosa endogenous peptide target and bind to cancer pathway receptor proteins such as MMP9, MAPK1, SRC, and PI3KCA, indicating their potential anticancer activity. This study provides valuable information for further research and the development of novel anti-cancer drugs.</p>","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"80 1","pages":"70"},"PeriodicalIF":3.1,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143426036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Endophytic Fungus CA3-A with Biotransformation or Catalysis Activity on the Metabolite Formation of Traditional Chinese Medicinal Astragalus Membranaceus var. Mongholicus (Bunge) P. K. Hsiao.","authors":"Ding-Hui Feng, Jin-Long Cui","doi":"10.1007/s11130-025-01317-8","DOIUrl":"10.1007/s11130-025-01317-8","url":null,"abstract":"<p><p>The effect of endophytic fungal biotransformation on the formation of metabolic substances has become a non-negligible factor in assessing the quality of medicinal plants. However, the relevant evidences are still particularly lacking. In this study, an endophytic fungus CA3-A with biotransformation activity was screened and identified as Talaromyces coprophilus from root of Astragalus mongholicus. Its biotransformation effect on host metabolism was studied by co-culture with fungus and host root. The results showed that in addition to the significant changes in primary metabolites, secondary metabolite conversions are mainly focused on compounds such as terpenoids, phenols and flavonoids. The transformed metabolic pathways are mainly enriched in glycerophospholipid metabolism, ubiquinone and terpenoid quinones biosynthesis, and tyrosine metabolism. A total of 38 signature differential metabolites are found through multivariate statistical analysis. In addition to eleven primary metabolites including glycerides and glycerophospholipids, twenty-eight secondary metabolites distribute in terpenes, sterols, phenols, flavonoids, benzene, lipids and other classes of compounds, respectively. In conclusion, this study aims to quickly focus on the signature differentially metabolites from a large amount of information, narrow the possible range of potential transformation products, and provide help for understanding of influence of endophytes on host metabolism and the search for new natural products.</p>","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"80 1","pages":"69"},"PeriodicalIF":3.1,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143426038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biofortified Sweet Potato Submitted to Different Domestic Cooking Processes: Impact on β-Carotene Retention and Antioxidant Capacity.","authors":"Eduardo Lorencetti Fornazier, Cíntia Tomaz Sant Ana, Daniela da Silva Oliveira, Neuza Maria Brunoro Costa, Joel Camilo Souza Carneiro, Pollyanna Ibrahim Silva","doi":"10.1007/s11130-025-01318-7","DOIUrl":"10.1007/s11130-025-01318-7","url":null,"abstract":"<p><p>Sweet potato (Ipomoea batatas) is a source of fiber, carbohydrates, minerals and phytochemicals such as carotenoids and phenolic compounds. Biofortification with provitamin A carotenoid improves the nutritional properties of sweet potatoes and can contribute to reducing the deficiency of this micronutrient, but cooking may affect its composition. In this context, this study aimed to evaluate the effect of seven different domestic cooking processes (deep frying, air frying, steaming, boiling, pressure cooking, baking, and microwave cooking) on the color, phenolic compounds, antioxidant activity, and real retention of β-carotene in biofortified sweet potatoes. The air frying was the process that promoted more remarkable changes on the color (p < 0.05). The air fryer was the most recommended domestic processes for maintaining phenolic compounds and antioxidant capacity, while the oven was the least recommended method (p < 0.05). Pressure cooking and boiling were the most recommended methods for greater β-carotene real retention, whereas air fryer resulted in the greatest β-carotene losses in biofortified sweet potatoes (p < 0.05). Different conventional cooking methods influence the degree of loss of phytochemicals present in biofortified sweet potatoes, which can impact the consumption of these nutrients, and the efficiency of the food biofortification program.</p>","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"80 1","pages":"68"},"PeriodicalIF":3.1,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143409774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Wild Cherry Prunus microcarpa: Phytochemical Characterization by LCESI MS/MS Technique and its Cytotoxicity, and Pro-apoptotic Actions.","authors":"Ahmed AbdulJalal AbdulJabbar, Parween AbdulSamad Ismail","doi":"10.1007/s11130-025-01298-8","DOIUrl":"10.1007/s11130-025-01298-8","url":null,"abstract":"<p><p>Nutraceuticals and natural products constitute nearly 50% of all cancer treatments due to their maximum efficiency and reduced side effects compared to synthetic chemicals. Thus, the present work investigates the anti-proliferative and apoptotic-stimulating effects of methanolic extracts of wild Prunus microcarpa fruits (MEPMF) and stems (MEPMS) and their phytochemical profiles. The cytotoxicity and pro-apoptotic effects (using MTT and flow cytometry assays) of MEPMF and MEPMS against U-87 MG, PC3, MCF-7, and HT-29 cells and normal human embryonic lung fibroblast cell (WI-38) were analyzed. The liquid chromatography-tandem mass spectrometry was established to determine some phyto-constituents of extracts. Thirty-four chemical compounds were found in MEPMF and MEPMS, including quinic acid (67.218 mg/g extract) and epicatechin (70.547 mg/g extracts) as the most common compounds, respectively. MEPMF exhibited a higher selectivity index and better inhibitory potentials, IC₅₀: 96.16, 102.35, and 214.94 µg/mL against HT-29, MCF-7 cells, and U-87MG cells, respectively, except for PC-3 cells compared to MEPMS. The pro-apoptotic actions of MEPMF were significantly higher on the U-87MG and HT-29 cancer cells compared to other cells and MEPMS. In contrast, MCF-7 and HT-29 cells showed reduced direct sensitivity to MEPMF and MEPMS treatments, respectively. Both extracts showed a non-toxic/safe effect on WI-38 cells and a noticeable cytotoxic and pro-apoptotic potential against four human cancer cells, with IC₅₀ ordering list HT-29 < MCF-7 < PC-3 < U-87MG. The present determined phytochemical and bioactivities provoke future molecular isolation and identification as a viable source for a potent pharmaceutical formulation.</p>","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"80 1","pages":"67"},"PeriodicalIF":3.1,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143409797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phytochemical Analysis of Triphala Extract, In Vitro and In Silico Evaluation of Pancreatic Lipase Inhibition for Obesity Management.","authors":"Sanjay Kottekad, Usharani Dandamudi","doi":"10.1007/s11130-025-01303-0","DOIUrl":"10.1007/s11130-025-01303-0","url":null,"abstract":"<p><p>Pancreatic lipase (PL) inhibition is a prominent pharmacological strategy for managing obesity, as it reduces the hydrolysis of dietary triglycerides (TAG) into free fatty acids and monoglycerides. Orlistat, an FDA-approved drug, achieves a 30% reduction in body fat through irreversible covalent inhibition of PL. However, the gastrointestinal side effects limit its long-term use. To address these issues, we explored inhibition using natural compounds from Triphala (TRI), a renowned Ayurvedic formulation comprising three plants - Emblica officinalis (EO), Terminalia bellirica (TB), and Terminalia chebula (TC). This study investigated PL inhibition by an 80% hydro-ethanolic extract of individual herbs (EO, TB, TC) as well as, Triphala (TRI) and its fractions and identified key bioactive compounds - Ellagic acid, Chebulic acid and Corilagin via LC-MS/MS. Qualitative and quantitative phytochemical analyses revealed that TF1 is rich in phenols and tannins and exhibited significant PL inhibition compared to individual herb extracts. Additionally, Ellagic acid, Chebulic acid and Corilagin of TF1 demonstrated notable PL-inhibition, with IC₅₀ values 58.41 ± 1.92 µg/mL, 125.33 ± 2.80 and 257.81 ± 2.10 µg/mL respectively. Furthermore, the PL inhibition kinetics showed that these bioactives and TRI fractions exhibited mixed inhibition, in contrast to the competitive inhibition of Orlistat (positive control). Molecular docking and 100 ns molecular dynamic simulations of PL-inhibitor complexes revealed that the bioactives bind to key residues in the PL active site. Among the three bioactives, Chebulic acid has better binding energy, primarily due to its substantial electrostatic interactions with the gatekeeper residue D80 of the PL active site. These findings highlight the potential of Triphala bioactives, particularly Chebulic acid and Ellagic acid, to effectively inhibit PL and provide a strategy to manage obesity.</p>","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"80 1","pages":"65"},"PeriodicalIF":3.1,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143409796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploration of UHPLC-ESI-QTOF-MS Profiles and the Neuroprotective, Antidiabetic, Antioxidant and Cytotoxic Effects of Extracts from Achillea maritima (L.) Ehrend. & Y.P.Guo (Asteraceae) Collected in Türkiye.","authors":"Shakeel Ahmed, Gokhan Zengin, Álvaro Fernández-Ochoa, Maria de la Luz Cádiz-Gurrea, Francisco Javier Leyva-Jiménez, Omer Elkiran, Ugur Cakilcioglu, Bengusu H Akgul, Catarina G Pereira, Luísa Custódio","doi":"10.1007/s11130-025-01314-x","DOIUrl":"10.1007/s11130-025-01314-x","url":null,"abstract":"<p><p>The current study investigated the chemical composition, antioxidant activity, enzyme inhibition, and cytotoxic activities of extracts from Achillea maritima, a wild medicinal plant used for various therapeutic purposes. The antioxidant activities were assayed through different assays like DPPH, ABTS, CUPRAC, FRAP, and phosphomolybdenum, whereas in enzyme inhibition studies, cholinesterase, tyrosinase, α-amylase, and α-glucosidase were assayed. Cytotoxicity studies are conducted on S17, RAW, and HepG2 to assess its selectivity and effectiveness. Chemical profiling by UHPLC-ESI-QTOF-MS revealed multiple bioactive compounds in the extracts. Polar solvents (ethanol, ethanol/water, and water) resulted in high concentrations of phenolic acids as well as chlorogenic and caffeoylquinic acids, as well as flavonoids like vicenin and apigenin. On the other, the nonpolar (hexane extract) was rich in octadecatrienoic acid hydroperoxy and hydroxyoctadecatrienic acid. Among these, the water extract contained the highest phenolic content of 32.26 mg GAE/g, while the ethyl acetate extract was the richest in flavonoids, with 7.83 mg RE/g. In the antioxidant studies, the water and ethanol/water extracts consistently display the most potent activities, thus indicating their significant free radical scavenging and metal chelation abilities. The studies on enzyme inhibitions showed remarkable BChE inhibitory activities of the ethanol extract in 12.50 mg GALAE/g, thus showing potential in managing disease conditions related to cholinesterase. Tyrosinase inhibition was significant by the ethanol extract, presenting 55.59 mg KAE/g. The ethyl acetate extract exhibited the most potent inhibitory activity against α-amylase with 0.66 mmol ACAE/g, while ethanol extract showed significant inhibition of α-glucosidase with 4.35 ACAE/g. Cytotoxicity results showed that the water extract was most effective against the HepG2 cancer cell line by reducing cell viability to 38.4% at high doses while preserving low toxicity against normal cells, as observed by high viability percentages in S17 and RAW cell lines. These results highlight the usefulness of A. maritima extracts in nutraceutical, pharmaceutical, and cosmeceutical applications.</p>","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"80 1","pages":"66"},"PeriodicalIF":3.1,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11825534/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143409775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Ultra-High-Pressure Synergistic Different Drying Methods on Storage Quality of Cistanche deserticola.","authors":"Min Liu, Jie Gao, Tao Sun, Yilan Wu, Tungalag Dong, Xueyan Yun","doi":"10.1007/s11130-025-01306-x","DOIUrl":"10.1007/s11130-025-01306-x","url":null,"abstract":"<p><p>Post-harvest enzymatic browning in Cistanche deserticola (C. deserticola), widely used in China for food and medicine, degrades its bioactive compounds. This study evaluated the effects of ultra-high-pressure (UHP) pretreatment combined with different drying methods on phenylethanoid glycosides (PhGs) retention and assess the impact of packaging materials on storage quality and shelf life. UHP pretreatment, a non-thermal processing method, was applied before hot air drying (HA) or freeze drying (FD). Single-factor experiments and Response Surface Methodology were used for process optimization. Optimal UHP-HA conditions (296 MPa, 16 min, 81 °C) yielded a PhGs retention of 5.12 mg/g fresh weight (FW), a 1.8-fold increase compared to direct HA, while optimal UHP-FD conditions (295 MPa, 16 min, -43 °C pre-freezing) achieved a PhGs retention of 4.08 mg/g·FW, a 1.7-fold increase compared to direct FD. UHP pretreatment enhanced PhGs retention in C. deserticola by disrupting its cell walls, facilitating the release of bound compounds, and reducing enzymatic degradation during drying. In packaging, the combined use of deoxidizers and desiccants effectively maintained moisture, inhibited microbial growth, and delayed active compound degradation. Accelerated shelf-life prediction indicated that this approach could extend the shelf life of C. deserticola from 256 to 663 days. These findings offer practical strategies to enhance the quality, shelf life, and application potential of C. deserticola in functional foods and traditional medicine, with broad market potential.</p>","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"80 1","pages":"58"},"PeriodicalIF":3.1,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143383128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}