Pain managementPub Date : 2024-02-01Epub Date: 2024-01-31DOI: 10.2217/pmt-2023-0079
Muath Aldosari, Yahya Alnashri, Jessica Jaiswal, Tejasvita Chandel, Emma Sophia Kay
{"title":"Opioid misuse among people with HIV: results from the National Survey on Drug Use and Health (NSDUH) 2015-2019.","authors":"Muath Aldosari, Yahya Alnashri, Jessica Jaiswal, Tejasvita Chandel, Emma Sophia Kay","doi":"10.2217/pmt-2023-0079","DOIUrl":"10.2217/pmt-2023-0079","url":null,"abstract":"<p><p><b>Aim:</b> Pain is a major challenge in the management of HIV/AIDS. This research analyzed the prevalence of substance use and opioid misuse among people with HIV (PWH) and those without (PWoH) in the USA. <b>Methods:</b> Using data from the 2015-2019 National Survey on Drug Use and Health, the study assessed misuse of pain relievers and opioids in 279,025 individuals. <b>Results:</b> PWH were about 1.88-times more likely to misuse pain relievers and 1.85-times to misuse opioids than PWoH, with a notable rise in hydrocodone and tramadol misuse. <b>Conclusion:</b> The data highlights an imperative for interventions targeting substance misuse among PWH, addressing the complex nexus of HIV, chronic pain and opioid use.</p>","PeriodicalId":20000,"journal":{"name":"Pain management","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139642690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain managementPub Date : 2024-01-01Epub Date: 2024-05-08DOI: 10.1080/17581869.2024.2343648
Beatriz Sora, Rubén Nieto, Helena Vall-Roqué, Jordi Conesa, Antoni Pérez-Navarro, Francesc Saigí-Rubió
{"title":"Chronic neck and low back pain from personal experiences: a written narrative approach.","authors":"Beatriz Sora, Rubén Nieto, Helena Vall-Roqué, Jordi Conesa, Antoni Pérez-Navarro, Francesc Saigí-Rubió","doi":"10.1080/17581869.2024.2343648","DOIUrl":"10.1080/17581869.2024.2343648","url":null,"abstract":"<p><p><b>Background:</b> Chronic neck and low back pain are very common and have detrimental effects for people and society. In this study, we explore the experiences of individuals with neck and/or back pain using a written narrative methodology. <b>Materials & methods:</b> A total of 92 individuals explained their pain experience using written narratives. Narratives were analyzed through thematic analysis and text data mining. <b>Results:</b> Participants wrote about their experience in terms of pain characteristics, diagnosis process, pain consequences, coping strategies, pain triggers, well-being and future expectations. Text data mining allowed us to identify concurrent networks that were basically related with pain characteristics, management and triggers. <b>Conclusion:</b> Written narratives are useful to understand individuals' experiences from their point of view.</p>","PeriodicalId":20000,"journal":{"name":"Pain management","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11229442/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140877057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain managementPub Date : 2024-01-01Epub Date: 2024-05-31DOI: 10.1080/17581869.2024.2348989
Vladimir Zah, Filip Stanicic, Djurdja Vukicevic, Dimitrije Grbic
{"title":"Economic burden and dosing trends of buprenorphine buccal film and transdermal patch in chronic low back pain.","authors":"Vladimir Zah, Filip Stanicic, Djurdja Vukicevic, Dimitrije Grbic","doi":"10.1080/17581869.2024.2348989","DOIUrl":"10.1080/17581869.2024.2348989","url":null,"abstract":"<p><p><b>Aim:</b> Exploring prescribing trends and economic burden of chronic low back pain (cLBP) patients prescribed buprenorphine buccal film (Belbuca®) or transdermal patches. <b>Methods:</b> In the MarketScan® commercial insurance claims (employees and their spouses/dependents, 2018-2021), the first film or patch prescription date was an index event. The observation covered 6-month pre-index and 12-month post-index periods. <b>Results:</b> Patients were propensity-score matched (708 per cohort). Buprenorphine initiation had stable cost trends in buccal film and increasing trends in transdermal patch cohort. Between-cohort comparisons of healthcare expenditures, cost trends and resource utilization showed significant differences, mostly in favor of buccal film. Buccal film also had higher daily doses and wider dosing range. <b>Conclusion:</b> Buprenorphine film is more cost-effective cLBP treatment with more flexible dosing.</p>","PeriodicalId":20000,"journal":{"name":"Pain management","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11229441/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141470026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain managementPub Date : 2024-01-01Epub Date: 2024-10-08DOI: 10.1080/17581869.2024.2406217
Karina Alejandra Ortega Agon, Karol Nathalia Cabeza Diaz, Anamaria Camargo Cardenas, Mario Andres Leotau, German William Rangel Jaimes, David Jose Garay Barbosa
{"title":"Radiofrequency ablation of bilateral splanchnic nerves in a 15-year-old patient with visceral abdominal pain cancer.","authors":"Karina Alejandra Ortega Agon, Karol Nathalia Cabeza Diaz, Anamaria Camargo Cardenas, Mario Andres Leotau, German William Rangel Jaimes, David Jose Garay Barbosa","doi":"10.1080/17581869.2024.2406217","DOIUrl":"10.1080/17581869.2024.2406217","url":null,"abstract":"<p><p>Pain, a prevalent and debilitating symptom in cancer patients, significantly diminishes the quality of life for both individuals and their families. Addressing this critical issue, our study presents the case of a 15-year-old diagnosed with synchronous multifocal multicentric osteosarcoma. We utilized radiofrequency ablation of bilateral splanchnic nerves, a strategy of multimodal pain and palliative care. This approach not only proved to be safe and effective but also markedly improved the patient's quality of life. Our findings shine a light of hope, emphasizing the paramount importance of innovative pain management in pediatric oncology, especially in the final stages of life. This case report highlights the unwavering dedication to excellence in relieving suffering, offering hope for patients grappling with cancer.</p>","PeriodicalId":20000,"journal":{"name":"Pain management","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11487957/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142392329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain managementPub Date : 2024-01-01Epub Date: 2024-06-28DOI: 10.1080/17581869.2024.2368451
Rajendra Prasad Anne, Emine A Rahiman
{"title":"Analgesic utility of automatic lancing device for heel prick in neonates: a systematic review and meta-analysis.","authors":"Rajendra Prasad Anne, Emine A Rahiman","doi":"10.1080/17581869.2024.2368451","DOIUrl":"10.1080/17581869.2024.2368451","url":null,"abstract":"<p><p><b>Background:</b> This systematic review and meta-analysis assessed the benefits of an automatic lancing device compared with a manual lancet or a hypodermic needle in neonates.<b>Materials & methods:</b> We followed the Cochrane Handbook methodology, used the RoB-2 tool for risk of bias assessment, RevMan 4.1 for meta-analysis and GRADE framework for certainty assessment. We searched the databases and gray literature on 15 November 2023.<b>Results:</b> Six eligible studies enrolling 539 neonates were included. An automatic lancing device reduced pain scores during and after heel prick, sampling time and the need for repeat puncture. The certainty of evidence was very low to moderate.<b>Conclusion:</b> An automatic lancing device is preferred for heel pricks in neonates, given less pain and higher efficiency.<b>PROSPERO registration number:</b> CRD42023483189.</p>","PeriodicalId":20000,"journal":{"name":"Pain management","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11485952/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141470067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain managementPub Date : 2024-01-01Epub Date: 2024-01-09DOI: 10.2217/pmt-2023-0080
Alice L Ye, Emily W Sudek, Daniela Magdaleno, Carlos J Roldan
{"title":"Diagnostic and therapeutic value of intracellular biomarker testing in chronic pain.","authors":"Alice L Ye, Emily W Sudek, Daniela Magdaleno, Carlos J Roldan","doi":"10.2217/pmt-2023-0080","DOIUrl":"10.2217/pmt-2023-0080","url":null,"abstract":"<p><p><b>Aim:</b> Micronutrient and metabolic compound supplementation as a method of treating chronic pain is not well understood. <b>Case:</b> A 58 year-old woman presented with refractory painful neuropathy. She did not respond to conservative treatment and was seeking spinal cord stimulator implantation. She underwent a biomarker panel that revealed low intracellular levels of multiple compounds. As she supplemented her deficiencies, her symptoms fully resolved, and the implant was no longer indicated. <b>Discussion:</b> Micronutrient and metabolic compound testing could potentially expand non-invasive treatment options for patients with refractory chronic pain. Caution should be exercised given limited regulatory oversight in the supplement industry and actively ongoing nutritional research. <b>Conclusion:</b> Biomarker testing panels may be a useful adjunct in the management of refractory neuropathic pain.</p>","PeriodicalId":20000,"journal":{"name":"Pain management","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139404012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain managementPub Date : 2024-01-01Epub Date: 2024-09-24DOI: 10.1080/17581869.2024.2402213
William Tyler Crawley, Timbre Backen, Barbara Melendez, Stephen Annest
{"title":"A surgical approach to complex regional pain syndrome with neurogenic thoracic outlet syndrome in a reoperation patient.","authors":"William Tyler Crawley, Timbre Backen, Barbara Melendez, Stephen Annest","doi":"10.1080/17581869.2024.2402213","DOIUrl":"10.1080/17581869.2024.2402213","url":null,"abstract":"<p><p>Thoracic outlet syndrome (TOS) and complex regional pain syndrome (CRPS) are two etiologies of chronic pain. TOS is a group of conditions that occur due to compression of the neurovascular structures of the upper extremity while CRPS is a disorder characterized by chronic and unremitting pain. This case highlights the experience of a 22-year-old female who presented following a traumatic injury to her left arm and was initially diagnosed with neurogenic TOS and later CRPS. Over a 10-year-period, she underwent a total of four operations to try and address her debilitating pain. In our third-time reoperation, symptoms of both pathologies nearly completely resolved with extensive neurolysis of the left brachial plexus and application of a scar tissue barrier.</p>","PeriodicalId":20000,"journal":{"name":"Pain management","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11487965/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142308278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain managementPub Date : 2024-01-01Epub Date: 2024-09-26DOI: 10.1080/17581869.2024.2400951
Lara Zador
{"title":"Pain specialists in the management of sickle cell disease: a call to action.","authors":"Lara Zador","doi":"10.1080/17581869.2024.2400951","DOIUrl":"10.1080/17581869.2024.2400951","url":null,"abstract":"","PeriodicalId":20000,"journal":{"name":"Pain management","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11487983/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142351885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain managementPub Date : 2024-01-01Epub Date: 2024-10-08DOI: 10.1080/17581869.2024.2408215
Márcio José Leão Nunes Filho, Eduardo Silva Reis Barreto, César Romero Antunes Júnior, Vinicius Borges Alencar, Liliane Elze Falcão Lins-Kusterer, Liana Maria Torres de Araujo Azi, Durval Campos Kraychete
{"title":"Efficacy of antidepressants in the treatment of chronic nonspecific low back pain: a systematic review and meta-analysis.","authors":"Márcio José Leão Nunes Filho, Eduardo Silva Reis Barreto, César Romero Antunes Júnior, Vinicius Borges Alencar, Liliane Elze Falcão Lins-Kusterer, Liana Maria Torres de Araujo Azi, Durval Campos Kraychete","doi":"10.1080/17581869.2024.2408215","DOIUrl":"10.1080/17581869.2024.2408215","url":null,"abstract":"<p><p><b>Aim:</b> This study reassesses the efficacy and safety of antidepressants in treating nonspecific chronic low back pain (NCLBP).<b>Materials & methods:</b> A systematic review was conducted following PRISMA guidelines, including randomized clinical trials (RCTs) from PubMed, Embase, Scopus, LILACS, SciELO and Cochrane CENTRAL, published through August 2024. Studies compared antidepressants with placebo or active comparators. The primary outcomes were pain relief and quality of life. Protocol registration: www.crd.york.ac.uk/prospero identifier is CRD42023307516.<b>Results:</b> Nine RCTs involving 1758 patients were analyzed. The antidepressants examined included duloxetine, escitalopram, bupropion, amitriptyline, imipramine and desipramine. Duloxetine 60 mg significantly reduced pain (MD = -0.57; 95% CI = -0.78 to -0.36) and improved quality of life compared with placebo, with side effects that were generally tolerable. Notably, higher doses of duloxetine (120 mg) were associated with an increase in adverse events. However, other antidepressants like amitriptyline and escitalopram demonstrated only modest or inconsistent effects.<b>Conclusion:</b> Duloxetine at 60 mg provides consistent pain relief and improves the quality of life in NCLBP, but higher doses increase adverse events. Escitalopram might offer modest benefits but should be considered a third-line treatment. Other antidepressants, such as amitriptyline, bupropion, imipramine and desipramine, have limited evidence supporting their efficacy and are associated with adverse effects.</p>","PeriodicalId":20000,"journal":{"name":"Pain management","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11487954/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142392328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}