Pain management最新文献_第10页

Adaptive dual-modality neuromodulation for chronic pain and muscle dysfunction: real-world insights from the NXTSTIM™ EcoAI digital platform. 慢性疼痛和肌肉功能障碍的自适应双模态神经调节：来自NXTSTIM™EcoAI数字平台的真实世界见解。

IF 1.7

Pain management Pub Date : 2026-07-01 Epub Date: 2026-04-19 DOI: 10.1080/17581869.2026.2661844

Maja Green, Bart Billet, Maria Kappell, Shari Kappell, Krishnan Chakravarthy

{"title":"Adaptive dual-modality neuromodulation for chronic pain and muscle dysfunction: real-world insights from the NXTSTIM™ EcoAI digital platform.","authors":"Maja Green, Bart Billet, Maria Kappell, Shari Kappell, Krishnan Chakravarthy","doi":"10.1080/17581869.2026.2661844","DOIUrl":"10.1080/17581869.2026.2661844","url":null,"abstract":"Background: Chronic musculoskeletal pain is often inadequately managed with pharmacologic therapy. Although transcutaneous electrical nerve stimulation (TENS) and electrical muscle stimulation (EMS) are established noninvasive modalities, conventional systems lack personalization and adherence monitoring.Objective: To evaluate real-world outcomes associated with the EcoAI adaptive dual-modality (TENS+EMS) neuromodulation platform for chronic pain management.Design, setting and participants: Retrospective analysis of de-identified symptom diaries from 2,135 adults with chronic musculoskeletal pain using EcoAI at home in the United States between January 2023 and September 2025.Intervention: AI-modulated TENS/EMS delivered via wearable surface electrodes with continuous algorithmic adjustment based on patient feedback. Three modes were available: Relieve (pain-focused TENS), Relax (combined TENS+EMS), and Strengthen (EMS-focused).Main outcomes and measures: Primary outcome was change in pain intensity measured on a 0-10 numeric rating scale. Secondary outcomes included muscle stiffness, fatigue, weakness, and spasm frequency measured on 0-4 ordinal scales. Longitudinal mixed-effects models assessed outcomes, with adherence evaluated as a modifier.Results: Significant improvements occurred in muscle weakness, fatigue, and spasm frequency among Strengthen-module users, while pain and stiffness remained stable. Higher adherence and baseline pain predicted greater pain reduction. No device-related adverse events occurred. Conclusion: Adaptive AI-guided TENS/EMS improved neuromuscular symptoms in real-world use significantly.","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"779-788"},"PeriodicalIF":1.7,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13336299/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147723631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of the Gigstride wearable device for pain reduction and functional outcomes in patients with lower extremity mobility deficits: a single-arm pilot feasibility study. 评估Gigstride可穿戴设备对下肢活动障碍患者的疼痛减轻和功能结局：单臂试点可行性研究

IF 1.7

Pain management Pub Date : 2026-07-01 Epub Date: 2026-05-07 DOI: 10.1080/17581869.2026.2664763

Ahmed Khawer, Johnny Dang, Alejandra Rojas-Cardenas, Daniel Khokhar, Ankur Jain, Brandon J Goodwin, Justin Crane, Michael Crimmins, Eric Muneio, Akhil Chhatre

{"title":"Evaluation of the Gigstride wearable device for pain reduction and functional outcomes in patients with lower extremity mobility deficits: a single-arm pilot feasibility study.","authors":"Ahmed Khawer, Johnny Dang, Alejandra Rojas-Cardenas, Daniel Khokhar, Ankur Jain, Brandon J Goodwin, Justin Crane, Michael Crimmins, Eric Muneio, Akhil Chhatre","doi":"10.1080/17581869.2026.2664763","DOIUrl":"10.1080/17581869.2026.2664763","url":null,"abstract":"Background: Mobility deficits are the most common form of disability in the United States and can significantly impair function and activities of daily living. Assistive devices have the potential to reduce physical limitations and support functional independence. This pilot study evaluated the Gigstride wearable device for its effects on pain reduction and gait-related outcomes.Methods: This prospective, single-arm feasibility study was conducted at a tertiary academic center and included adults ≥18 years with lower extremity deficits. The primary outcome was pain, measured by the Numeric Rating Scale (NRS) during level ambulation and stair climbing. Secondary outcomes included performance on the modified 10-meter walk test with return and the Timed Up and Go (TUG) test. Patient-reported experience and the practicality of implementing the device in a larger-scale study were also assessed.Results: A total of forty-four patients were enrolled (mean age 66 years; 57% female). Gigstride use significantly reduced pain during level ambulation and stair climbing, with no significant changes in secondary outcomes. Median walking pain decreased by 1 NRS point (p = 0.00032), and stair-related pain decreased by 0.5 NRS points (p = 0.00025).Conclusion: Gigstride wearable device use appears feasible and may provide modest reductions in mobility-related pain. However, the limited magnitude of pain reduction and absence of functional improvement in this study highlights the need for larger, controlled studies.Clinical trial registration: The www.ClinicalTrials.gov identifier is NCT06548087.","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"789-797"},"PeriodicalIF":1.7,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13336283/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147841542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Beyond pain: how socioeconomic and psychosocial factors shape medication use in knee osteoarthritis - a cross-sectional study. 超越疼痛：社会经济和社会心理因素如何影响膝关节骨关节炎的药物使用-一项横断面研究。

IF 1.7

Pain management Pub Date : 2026-07-01 Epub Date: 2026-04-24 DOI: 10.1080/17581869.2026.2663941

Natália Aparecida Casonato, Filipe Estevão Sette, Marialice Gyaraki da Silva, Jessica Bianca Aily, Gerson Jhonatan Rodrigues, Stela Marcia Mattiello

{"title":"Beyond pain: how socioeconomic and psychosocial factors shape medication use in knee osteoarthritis - a cross-sectional study.","authors":"Natália Aparecida Casonato, Filipe Estevão Sette, Marialice Gyaraki da Silva, Jessica Bianca Aily, Gerson Jhonatan Rodrigues, Stela Marcia Mattiello","doi":"10.1080/17581869.2026.2663941","DOIUrl":"10.1080/17581869.2026.2663941","url":null,"abstract":"Aims: Chronic pain and disability are the main symptoms of knee osteoarthritis (KOA). Pharmacological therapy is widely employed for pain relief, although its efficacy and safety vary with clinical, socioeconomic, and psychosocial conditions. The objective of this research was to explore the relationships among pain medication profiles and psychosocial, economic, and educational factors in people with KOA.Methods: A cross-sectional study included 211 adults with KOA; medication use was verified via Drugs.com®. Multivariable logistic regression analyzed the associations of pain intensity (NPRS), pain catastrophizing (PCS), kinesiophobia (TSK), education, and income with polypharmacy and potential drug-drug interactions (DDIs).Results: Higher PCS scores were associated with increased odds of polypharmacy (OR = 1.34; 95% CI 1.01-1.68) and potential DDIs (OR = 2.16; 95% CI 1.01-4.62). Income above five minimum wages further raised these odds (polypharmacy OR = 6.07; DDIs OR = 12.08). In contrast, Secondary and Higher Education were protective against DDIs (OR = 0.32 and 0.26, respectively). Model fit was satisfactory (Tjur's R2 = 0.204 for polypharmacy; 0.182 for DDIs).Conclusions: Socioeconomic and psychosocial factors significantly influence the medication profile and pain experience of individuals with KOA, highlighting the importance of integrating clinical, social, and cognitive determinants in patient management.","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"755-764"},"PeriodicalIF":1.7,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13336257/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147778430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of transcutaneous electrical nerve stimulation associated to exercise for pain in Parkinson's disease: a randomized crossover clinical trial. 经皮神经电刺激与运动对帕金森病疼痛的影响：一项随机交叉临床试验

IF 1.7

Pain management Pub Date : 2026-07-01 Epub Date: 2026-05-04 DOI: 10.1080/17581869.2026.2660894

P A Garcez, B M DeJesus, L R Oliveira, L V Lima, J M DeSantana

{"title":"Effect of transcutaneous electrical nerve stimulation associated to exercise for pain in Parkinson's disease: a randomized crossover clinical trial.","authors":"P A Garcez, B M DeJesus, L R Oliveira, L V Lima, J M DeSantana","doi":"10.1080/17581869.2026.2660894","DOIUrl":"10.1080/17581869.2026.2660894","url":null,"abstract":"Introduction: Parkinson's disease (PD) causes debilitating motor and non-motor symptoms, including chronic pain. While TENS and exercise are potential treatments, their combined effects require investigation.Objective: To assess the effect of TENS added to an exercise program on pain intensity (primary outcome), fatigue, temporal summation, pain catastrophizing, skin sensitivity, and depression in PD.Methods: This randomized, double-blind, crossover trial included 13 patients (Hoehn & Yahr II-III). Participants received active or placebo TENS (1:1 ratio) followed by the reverse order after a 7-day washout. Both phases included a 20-minute exercise program. Active TENS (100 Hz, 100 μs) was applied to thoracic and lumbar regions at motor threshold. Outcome assessors and participants were blinded to the intervention.Results: All 13 participants completed both phases (n = 26). Compared to placebo, the active TENS group showed significant improvements in primary outcome of pain intensity (p = 0.006). Significant improvements were also observed in temporal summation (p = 0.004) and cutaneous sensibility (thoracic right (p = 0.002), left (p = 0.041). No adverse events were reported during the interventions.Conclusions: TENS combined with exercise is effective for reducing pain intensity, temporal summation, and fatigue, as well as improving cutaneous sensibility in patients with PD.Clinical trial registration: ReBEC identifier is RBR-4bvwxq (UTN: U1111-1159-1101).","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"737-746"},"PeriodicalIF":1.7,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13336271/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147841451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reframing conservative neck pain management: from techniques to integrated, person-centered care. 重塑保守的颈部疼痛管理：从技术到综合的，以人为中心的护理。

IF 1.5

Pain management Pub Date : 2026-06-15 DOI: 10.1080/17581869.2026.2688371

Nathan Hutting, Giacomo Rossettini, Mauro Crestani, Chad E Cook, Firas Mourad, Jorge Hugo Villafañe

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Correction. 修正。

IF 1.5

Pain management Pub Date : 2026-06-11 DOI: 10.1080/17581869.2026.2687979

引用次数: 0

A case report exploring the use of subcutaneous Botox for the treatment of neuropathic pain in active head and neck cancer. 探讨皮下肉毒杆菌素治疗活动性头颈癌神经性疼痛的病例报告。

IF 1.7

Pain management Pub Date : 2026-06-01 Epub Date: 2026-04-22 DOI: 10.1080/17581869.2026.2660148

Ellie I Davidson, Kee Howe Wong, Smita L A Almeida, Matthew R D Brown

引用次数: 0

Can rimegepant stop symptoms of a migraine attack in people who have not found triptans to work well or are not recommended to use triptans? A plain language summary of a clinical study. 对于那些发现曲坦类药物效果不佳或不建议使用曲坦类药物的人来说，利美止能阻止偏头痛发作的症状吗？临床研究的简单语言总结。

IF 1.7

Pain management Pub Date : 2026-06-01 Epub Date: 2026-04-03 DOI: 10.1080/17581869.2026.2646705

Messoud Ashina, Peter McAllister, Charly Gaul, Adolfo Leyva-Rendon, Luz M Ramirez, Catherine Nalpas, Alexandra Thiry, Lucy Abraham, Robert J Fountaine, Terence Fullerton

引用次数: 0

Repeated virtual reality sessions in fibromyalgia: a prospective observational study. 纤维肌痛症的重复虚拟现实会议：一项前瞻性观察研究。

IF 1.7

Pain management Pub Date : 2026-06-01 Epub Date: 2026-03-02 DOI: 10.1080/17581869.2026.2635978

Jean-Marie Amodeo, Frederic Berthier, Cindy Biehlmann, Brigitte Piazza

{"title":"Repeated virtual reality sessions in fibromyalgia: a prospective observational study.","authors":"Jean-Marie Amodeo, Frederic Berthier, Cindy Biehlmann, Brigitte Piazza","doi":"10.1080/17581869.2026.2635978","DOIUrl":"10.1080/17581869.2026.2635978","url":null,"abstract":"Aims: Fibromyalgia (FM) is a chronic pain syndrome with limited effective treatments. This study evaluated virtual reality (VR) as an adjunct therapy.Methods: Participants used the HealthyMind program delivered via a Pico G2 4K Enterprise headset in eight supervised, seated 20-minute sessions over four weeks, featuring nature relaxation, guided imagery, and meditation. Primary outcome was Pain Numerical Rating Scale (NRS) at one month (M1); secondary outcomes included PCS, PSEQ, and HADS.Results: Fifty participants completed baseline and M1 assessments. Pain significantly decreased from 6.8 ± 1.5 to 5.8 ± 1.9 (-14.8%, p < 0.001; effect size = 0.56). Significant improvements were observed in catastrophizing, self-efficacy, anxiety, and depression.Conclusion: Repeated HealthyMind VR use was associated with reduced pain and improved psychological outcomes in FM patients.Clinical trial registration: www.clinicaltrials.gov identifier is (NCT05567861).","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"633-643"},"PeriodicalIF":1.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13228965/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147326845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Beyond pain: the role of body representation in the diagnosis and management of fibromyalgia. 超越疼痛：身体表征在纤维肌痛的诊断和治疗中的作用。

IF 1.7

Pain management Pub Date : 2026-06-01 Epub Date: 2025-11-17 DOI: 10.1080/17581869.2025.2591025

Víctor Riquelme Aguado, Antonio Gil Crujera, Francisco Gómez Esquer

引用次数: 0