Pain management最新文献

Factors associated with nonpharmacological treatment use among older adults with chronic low back pain tapering opioids. 慢性腰痛老年人非药物治疗使用阿片类药物的相关因素。

IF 1.5

Pain management Pub Date : 2025-10-03 DOI: 10.1080/17581869.2025.2567839

Liang-Yuan Lin, Omkar Ghodke, Cynthia Siddiqua, Sonia Eden, Yi Yang, Kaustuv Bhattacharya

{"title":"Factors associated with nonpharmacological treatment use among older adults with chronic low back pain tapering opioids.","authors":"Liang-Yuan Lin, Omkar Ghodke, Cynthia Siddiqua, Sonia Eden, Yi Yang, Kaustuv Bhattacharya","doi":"10.1080/17581869.2025.2567839","DOIUrl":"https://doi.org/10.1080/17581869.2025.2567839","url":null,"abstract":"Aims: To examine multilevel factors associated with nonpharmacological treatment (NPT) use during opioid tapering among older adults with chronic low back pain (cLBP).Methods: A cohort study was conducted using 2012-2020 5% national Medicare data. Older adults ≥65 with cLBP who initiated long-term opioid therapy and experienced subsequent tapering were included. The primary outcome was the receipt of NPT within 90 days of tapering. Guided by the social ecological model, predictors were assessed across individual, interpersonal, community, and organizational levels. Multivariable logistic regression was used to evaluate associations with NPT use.Results: A total of 10,811 eligible beneficiaries were identified. NPT use was more likely among Asian and female individuals, while those receiving partial low-income subsidies had lower odds. Residing in counties with more mental health providers and social associations was linked to higher NPT use. Prior NPT use, higher baseline opioid dose, rapid tapering, mental health conditions, substance use disorders, additional pain diagnoses, and higher comorbidity burden were associated with increased odds of NPT use.Conclusion: This study identified key factors affecting NPT use during opioid tapering among older adults with cLBP. Findings underscore the importance of targeted clinical and policy strategies to reduce disparities in NPT access.","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"1-11"},"PeriodicalIF":1.5,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145213434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Patient reported outcomes following genicular nerve radio frequency ablation for osteoarthritis-related knee pain. 患者报告了膝神经射频消融术治疗骨关节炎相关膝关节疼痛的结果。

IF 1.5

Pain management Pub Date : 2025-10-03 DOI: 10.1080/17581869.2025.2567833

Melissa Schwartz, Komal Luthra, Sophia Salingaros, Ahmed Khawer, Paulina Giacomelli, Ryan Roemmich, Pranamya Suri, Scott Benkovic, Akhil Chhatre

{"title":"Patient reported outcomes following genicular nerve radio frequency ablation for osteoarthritis-related knee pain.","authors":"Melissa Schwartz, Komal Luthra, Sophia Salingaros, Ahmed Khawer, Paulina Giacomelli, Ryan Roemmich, Pranamya Suri, Scott Benkovic, Akhil Chhatre","doi":"10.1080/17581869.2025.2567833","DOIUrl":"https://doi.org/10.1080/17581869.2025.2567833","url":null,"abstract":"Introduction: Genicular radiofrequency ablation (RFA) is a minimally invasive treatment for knee pain with variable outcomes reported. This study aimed to evaluate genicular RFA in reducing pain and identify predictors of treatment success.Methods: This retrospective study included 34 patients who underwent genicular RFA between April 2022 and December 2023. Data on demographics, pre- and post-procedure pain levels, and clinical variables were collected through chart reviews and follow-up surveys. The primary outcome was pain reduction at postoperative follow up. Statistical analyses were conducted to identify predictors of pain outcomes.Results: RFA led to pain reduction in 24 patients (71%), though only 9 (26%) achieved >50% relief according to IMMPACT criteria. The mean pre-procedure pain score was 7.1 ± 1.4, which decreased to 5.2 ± 2.0 post-procedure. Lower pre-procedure Numeric Rating Score (NRS) was the strongest predictor of success (P < 0.001), while age, BMI, gender, and arthritis severity did not significantly impact outcomes.Conclusion: While genicular RFA led to pain reduction in a majority of patients, only a subset experienced clinically significant improvement. Pre-procedure pain score was a key predictor of outcomes, suggesting the need for more refined patient selection criteria and further research into optimizing treatment targets.","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"1-6"},"PeriodicalIF":1.5,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145213392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Postoperative pain outcome following a superficial parasternal intercostal plane block in children undergoing pediatric heart surgery: a retrospective cohort study. 儿童心脏手术后浅胸骨旁肋间平面阻滞后的疼痛结局：一项回顾性队列研究。

IF 1.5

Pain management Pub Date : 2025-10-01 Epub Date: 2025-07-29 DOI: 10.1080/17581869.2025.2539667

Judith Stauff, Sebastian Kintrup, Markus Ramm, Andreas Brünen, Simone Ulrich, Edward Malec, Katarzyna Januszewska, Julia Stegger, Kerstin Trociewicz, Antje Gottschalk, Alexander Schnabel

{"title":"Postoperative pain outcome following a superficial parasternal intercostal plane block in children undergoing pediatric heart surgery: a retrospective cohort study.","authors":"Judith Stauff, Sebastian Kintrup, Markus Ramm, Andreas Brünen, Simone Ulrich, Edward Malec, Katarzyna Januszewska, Julia Stegger, Kerstin Trociewicz, Antje Gottschalk, Alexander Schnabel","doi":"10.1080/17581869.2025.2539667","DOIUrl":"10.1080/17581869.2025.2539667","url":null,"abstract":"Background: Aim of the present study was to investigate the postoperative pain outcome following the implementation of a superficial parasternal intercostal plane (SPIP) block in children undergoing cardiac surgery with a sternotomy.Methods: We conducted a retrospective cohort study in children undergoing extracardiac Fontan operation or a secundum atrial septal defect closure receiving a SPIP in addition to standard pain treatment versus standard pain treatment only. The primary outcome was the worst pain intensity within 24 hours (median (interquartile range)).Results: Mean age of the study groups (54 patients each) was 3.22 years (±0.95), respectively 4.26 years (±2.76) in the control group. There was no statistically significant reduction in worst pain intensity 24 hours after surgery in children treated with a SPIP block (3(1-5)) compared to control group (4(2-5)) (p1-tailed = 0.16, d = 0.19). However, 4 and 12 hours after surgery there were significant improvements in median pain intensity in children treated with a SPIP block (p1-tailed = 0.04).Conclusions: This study showed that implementation of a SPIP block might further improve postoperative pain management following cardiac surgery in children. However, due to lower baseline pain intensity in the control group primary outcome failed significantly. Therefore, further trials are urgently requested.","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"685-691"},"PeriodicalIF":1.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144732730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy and adverse effects of lower doses of ketorolac; a systematic review and meta-analysis. 低剂量酮咯酸的疗效及不良反应系统回顾和荟萃分析。

IF 1.5

Pain management Pub Date : 2025-10-01 Epub Date: 2025-09-16 DOI: 10.1080/17581869.2025.2560293

Maryam Bahreini, Heewa Rashnavandi, Fatemeh Rasooli, Alireza Jalali, Rasoul Masoumi, Hadi Mirfazaelian

引用次数: 0

GLP-1 agonists: a game changer in pain treatment and addiction. GLP-1激动剂：疼痛治疗和成瘾的游戏规则改变者。

IF 1.5

Pain management Pub Date : 2025-10-01 Epub Date: 2025-07-28 DOI: 10.1080/17581869.2025.2536998

Sahil Bade, Mark Friedrich B Hurdle, Sohail Bade, Sebastian Encalada, Sharima Kanahan-Osman, Sahil Gupta

{"title":"GLP-1 agonists: a game changer in pain treatment and addiction.","authors":"Sahil Bade, Mark Friedrich B Hurdle, Sohail Bade, Sebastian Encalada, Sharima Kanahan-Osman, Sahil Gupta","doi":"10.1080/17581869.2025.2536998","DOIUrl":"10.1080/17581869.2025.2536998","url":null,"abstract":"Chronic pain imposes a significant healthcare burden, with treatments often limited by side effects, opioid dependency, and preventable surgeries. Emerging evidence suggests that glucagon-like peptide-1 receptor agonists (GLP-1RAs), developed for diabetes and obesity, may offer novel analgesia and treat drug-seeking behavior. This review examines the role of GLP-1RAs in pain management, focusing on inflammation, macrophage repolarization, oxidative stress, and dopaminergic pathways in substance use disorders. We conducted a literature search in PubMed and Embase (Ovid) from January 2000 to February 2025, identifying studies on GLP-1RA and pain in headaches, osteoarthritis, diabetic neuropathy, and substance use disorders. GLP-1RAs offer a promising shift in pain management, potentially reducing opioid dependence, preventing surgical interventions, and lowering healthcare costs. While early evidence suggests analgesic and disease-modifying effects beyond weight loss, significant knowledge gaps remain. In osteoarthritis, they appear to reduce inflammation and cartilage degradation, but trials in non-obese, non-comorbid patients are needed. In diabetic neuropathy, GLP-1RAs show potential for nerve repair, but optimal dosing and long-term efficacy need clarification. Preclinical data support GLP-1RAs signaling in migraines, but human studies are lacking. Trials in alcohol addiction show promise, though evidence for other substances remains inconclusive. Larger-scale trials are needed to confirm these findings.","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"753-765"},"PeriodicalIF":1.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144732729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Medical management of musculoskeletal pain in professional wheelchair basketball players: an evidence-based guide. 专业轮椅篮球运动员肌肉骨骼疼痛的医学管理：循证指南。

IF 1.5

Pain management Pub Date : 2025-10-01 Epub Date: 2025-08-18 DOI: 10.1080/17581869.2025.2549242

Giacomo Farì, Danilo Donati, Roberto Tedeschi, Scheila Bellito, Giuseppe Palaia, Marco Filipponi, Giuseppe Rollo, Francesco Quarta, Andrea Bernetti

{"title":"Medical management of musculoskeletal pain in professional wheelchair basketball players: an evidence-based guide.","authors":"Giacomo Farì, Danilo Donati, Roberto Tedeschi, Scheila Bellito, Giuseppe Palaia, Marco Filipponi, Giuseppe Rollo, Francesco Quarta, Andrea Bernetti","doi":"10.1080/17581869.2025.2549242","DOIUrl":"10.1080/17581869.2025.2549242","url":null,"abstract":"Wheelchair basketball (WB) has evolved from a recreational activity to an internationally recognized sport. It is useful in enhancing psychophysical well-being in athletes with disabilities. However, WB professional players' medical management, especially regarding musculoskeletal pain (MSP), poses unique challenges and the related scientific literature still seems fragmentary. An extensive review of the PubMed, Cochrane, and Embase databases was performed to identify the available evidence regarding the medical management of WB players MSP. It emerges that WB players often face musculoskeletal injuries due to repetitive movements and game-specific actions. The management of these injuries requires a multidisciplinary approach. Firstly, the use of pharmacological treatments like Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) is common, though care must be taken to comply with World Anti-Doping Agency (WADA) regulations. Then, preventive strategies, including tailored rehabilitation and strength conditioning, are essential. Moreover, the use of dietary supplements, while popular for enhancing recovery and performance, carries risks, particularly contamination with prohibited substances. Therefore, medical staff must exercise caution when recommending supplements. Finally, this review highlights that WB players' MSP management requires balancing effective treatment with adherence to anti-doping rules, limiting the use of traditional drugs where possible and improving the clinical application of non-pharmacological treatments, such as physical and rehabilitation medicine approaches.","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"713-720"},"PeriodicalIF":1.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144874577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of adding metoclopramide to lidocaine on post-surgery pain in lower abdominal operations. 甲氧氯普胺联合利多卡因对下腹手术后疼痛的影响。

IF 1.5

Pain management Pub Date : 2025-10-01 Epub Date: 2025-07-26 DOI: 10.1080/17581869.2025.2539668

Masoud Saadat Fakhr, Zahra Pakdaman, Kiana Rezvanfar, Reza Shah Hosseini, Zahra Amini, Koosha Amiri, Mahnaz Narimani Zamanabadi

{"title":"Effect of adding metoclopramide to lidocaine on post-surgery pain in lower abdominal operations.","authors":"Masoud Saadat Fakhr, Zahra Pakdaman, Kiana Rezvanfar, Reza Shah Hosseini, Zahra Amini, Koosha Amiri, Mahnaz Narimani Zamanabadi","doi":"10.1080/17581869.2025.2539668","DOIUrl":"https://doi.org/10.1080/17581869.2025.2539668","url":null,"abstract":"Background: Effective postoperative pain management remains a critical challenge, particularly in lower abdominal surgeries where multimodal approaches are underexplored. This study aimed to evaluating the efficacy of this combination in reducing pain and analgesic requirements.Methods: In this double-blind, randomized controlled trial, 59 patients undergoing elective lower abdominal surgery were randomly assigned to receive either subcutaneous metoclopramide plus lidocaine or lidocaine alone after surgery. Postoperative pain scores were assessed at 1, 6, 12, and 24 hours using the Visual Analog Scale (VAS), and analgesic consumption was recorded over the first 24 hours.Results: 59 patients (mean age: 41.8 ± 11.8 years; 43.1% male, 56.9% female) receiving the metoclopramide-lidocaine combination demonstrated significantly lower pain scores at all assessed time points compared to lidocaine alone, with values of 5.2 ± 1.1 versus 7.7 ± 0.8 at 1 hour, 3.8 ± 0.9 versus 6.2 ± 0.9 at 6 hours (p = 0.004), 2.9 ± 1.0 versus 5.4 ± 1.4 at 12 hours, and 2.1 ± 0.7 versus 4.4 ± 1.1 at 24 hours postoperatively (p < 0.001). Furthermore, the combination group showed a 28.6% reduction in analgesic requirements during the first 24 hours (47.4 ± 18.1 mg vs 66.3 ± 25.2 mg, p = 0.002), highlighting the opioid-sparing effect of this approach.Conclusion: The addition of metoclopramide to subcutaneous lidocaine resulted in improved postoperative pain control and reduced analgesic requirements following lower abdominal surgeries under general anesthesia.Clinical trial registration: Iranian Registry of Clinical Trials identifier is IRCT20231228060548N1.","PeriodicalId":20000,"journal":{"name":"Pain management","volume":"15 10","pages":"677-683"},"PeriodicalIF":1.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145200536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of hyperbaric bupivacaine with fentanyl vs. hyperbaric bupivacaine with dexmedetomidine in reducing visceral pain during cesarean delivery under spinal anesthesia: study protocol. 高压布比卡因联合芬太尼与高压布比卡因联合右美托咪定减轻腰麻剖宫产时内脏疼痛的比较：研究方案。

IF 1.5

Pain management Pub Date : 2025-10-01 Epub Date: 2025-08-06 DOI: 10.1080/17581869.2025.2543232

Sujan Dhakal, Muskaan Shrestha, Elija Gautam, Allen Suwal, Salin Dhakal, Sita Dhakal

{"title":"Comparison of hyperbaric bupivacaine with fentanyl vs. hyperbaric bupivacaine with dexmedetomidine in reducing visceral pain during cesarean delivery under spinal anesthesia: study protocol.","authors":"Sujan Dhakal, Muskaan Shrestha, Elija Gautam, Allen Suwal, Salin Dhakal, Sita Dhakal","doi":"10.1080/17581869.2025.2543232","DOIUrl":"10.1080/17581869.2025.2543232","url":null,"abstract":"Background: The primary objective of this randomized, double-blind, parallel-group trial is to evaluate the efficacy and safety of intrathecal hyperbaric bupivacaine in conjunction with either fentanyl or dexmedetomidine in mitigating visceral pain during cesarean delivery.Method: One hundred and sixteen parturients, classified as ASA II-III and scheduled for elective cesarean section, will be randomized 1:1 into two groups: Group BF will receive 10 mg hyperbaric bupivacaine in combination with 10 µg fentanyl. In contrast, Group BD will receive 10 mg hyperbaric bupivacaine in combination with 5 µg dexmedetomidine. The primary outcome is the frequency and intensity of visceral pain, assessed using an 11-point numerical rating scale at pivotal intraoperative stages. Secondary outcomes include hemodynamic stability, neonatal Apgar scores, shivering frequency, and the incidence of adverse effects.Conclusion: The primary hypothesis of this study is that dexmedetomidine may offer superior visceral pain control with a reduced incidence of adverse effects.Making cesarean births more comfortable: Comparing Two Pain Relief Medicines Used in A cesarean birth (C-section) is often done under spinal anesthesia, which numbs the lower body, while the mother stays awake. While this works well for most women, some still feel uncomfortable or experience painful sensations in their belly during surgery, especially when the uterus is touched or moved. This kind of deep belly pain is called visceral pain.Clinical trial registration: www.clinicaltrials.gov identifier is NCT06367660; Nepal Health Research Council (NHRC) Protocol ID: 98-2024.","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"651-658"},"PeriodicalIF":1.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144789683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Letter in reply: "Open-label Placebos For Low Back Pain: Unresolved Challenges And Next Steps". 回信：“治疗腰痛的开放标签安慰剂：未解决的挑战和下一步”。

IF 1.5

Pain management Pub Date : 2025-10-01 Epub Date: 2025-07-24 DOI: 10.1080/17581869.2025.2539063

Victor Hugo Palhares Flávio-Reis, Yago Marcos Pessoa-Gonçalves, Antonieta Santos Andrade Lamoglia, Chamberttan Souza Desidério, Carlo José Freire Oliveira

引用次数: 0

A review of treatment options for chronic pelvic pain from endometriosis. 子宫内膜异位症引起的慢性盆腔疼痛的治疗方案综述。

IF 1.5

Pain management Pub Date : 2025-10-01 Epub Date: 2025-08-02 DOI: 10.1080/17581869.2025.2542713

Sebin Choi, Johnny Phuong Tran

引用次数: 0