Pain management最新文献

{"title":"Patient profiling and outcome assessment in spinal cord stimulation for chronic back and/or leg pain (the PROSTIM study): a study protocol.","authors":"Vincent Raymaekers, Sacha Meeuws, Lisa Goudman, Gregory Van der Steen, Maarten Moens, Maarten Vanloon, Dirk De Ridder, Tomas Menovsky, Jan Vesper, Mark Plazier","doi":"10.2217/pmt-2023-0103","DOIUrl":"10.2217/pmt-2023-0103","url":null,"abstract":"<p><p>Spinal cord stimulation (SCS) is a well-established treatment option in the multidisciplinary approach to chronic back and leg pain. Nevertheless, careful patient selection remains crucial to provide the most optimal treatment and prevent treatment failure. We report the protocol for the PROSTIM study, an ongoing prospective, multicentric and observational clinical study (NCT05349695) that aims to identify different patient clusters and their outcomes after SCS. Patients are recruited in different centers in Europe. Analysis focuses on identifying significant patient clusters based on different health domains and the changes in biopsychosocial variables 6 weeks, 3 and 12 months after implantation. This study is the first to include a biopsychosocial cluster analysis to identify significant patient groups and their response to treatment with SCS.</p>","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"677-687"},"PeriodicalIF":1.7,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138488241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perceptions of pain in aging females undergoing spinal cord stimulation.","authors":"Umm E Hani Abdullah, Sophie Kelly, Adam Ricker, Melisande Nabage, Olga Khazen, Ilknur Telkes, Marisa DiMarzio, Candy Wilson, Julie G Pilitsis","doi":"10.2217/pmt-2023-0100","DOIUrl":"10.2217/pmt-2023-0100","url":null,"abstract":"<p><p><b>Aim:</b> Effects of age and sex on chronic pain outcomes following spinal cord stimulation (SCS) have not yet been assessed. <b>Methods:</b> We retrospectively reviewed 1 year outcomes from a database of patients receiving thoracic SCS. Subjects were divided into four cohorts: pre-menopausal and post-menopausal females, and aged-matched males. Improvement using the numerical rating scale, Oswestry Disability Index (ODI), Beck's Depression Inventory (BDI), McGill Pain Questionnaire and Pain Catastrophizing Scale (PCS) was assessed. <b>Results:</b> Older females were notably different from males and females under 60 as they had greater improvements in ODI, BDI and PCS. Further, females ≥60 had greater improvement in PCS compared with males ≥60. <b>Conclusion:</b> Our findings suggest greater improvement with 1 year SCS treatment in post-menopausal females, compared with age-matched males.</p>","PeriodicalId":20000,"journal":{"name":"Pain management","volume":"13 12","pages":"701-708"},"PeriodicalIF":1.7,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139404015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Results of the Acupuncture in the Emergency Department for Pain Management (ACUITY) Multi-Center Feasibility Study","authors":"M. D. McKee, Robert Hughes, A. Karasz, Arya Nielsen, Ryung Kim, Jeffery A Dusek, Christopher Coyne, Jessica Surdam","doi":"10.1370/afm.22.s1.5273","DOIUrl":"https://doi.org/10.1370/afm.22.s1.5273","url":null,"abstract":"","PeriodicalId":20000,"journal":{"name":"Pain management","volume":"25 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139293735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Plain Language Summary to learn about relugolix combination therapy for the treatment of pain associated with endometriosis.","authors":"Linda C Giudice, Sawsan As-Sanie, Juan C Arjona Ferreira, Christian M Becker, Mauricio S Abrao, Bruce A Lessey, Krzysztof Dynowski, Krzysztof Wilk, Yulan Li, Vandana Mathur, Rachel B Wagman, Neil P Johnson","doi":"10.2217/pmt-2023-0052","DOIUrl":"10.2217/pmt-2023-0052","url":null,"abstract":"<p><strong>What is this summary about?: </strong>This is a summary of research studies (known as clinical trials) called SPIRIT 1 and SPIRIT 2. The SPIRIT 1 and SPIRIT 2 studies compared how well a medicine called relugolix combination therapy worked in relieving pain in women with moderate to severe endometriosis compared to a placebo, a pill with no active medication. Endometriosis occurs when tissue similar to what normally lines the uterus grows in other places, such as the ovaries, fallopian tubes, and bowels.</p><p><strong>What were the results?: </strong>Researchers looked at 1261 adult women with moderate to severe endometriosis. Randomly, 420 (33%) of these women were assigned to relugolix combination therapy, 420 (33%) were assigned to delayed relugolix combination therapy (relugolix alone first and then relugolix combination therapy for the remainder of the study), and 421 (33%) were assigned to placebo. The SPIRIT 1 and SPIRIT 2 studies showed that more women taking relugolix combination therapy (75% from SPIRIT 1 and 75% from SPIRIT 2) for 24 weeks had both less pelvic or groin pain during menstrual periods from endometriosis and no need for more pain medicines than women who took placebo (27% from SPIRIT 1 and 30% from SPIRIT 2). The SPIRIT 1 and SPIRIT 2 studies also showed that more women taking relugolix combination therapy (59% from SPIRIT 1 and 66% from SPIRIT 2) for 24 weeks had both less pelvic or groin pain between menstrual periods from endometriosis and no need for more pain medicines than women who took placebo (40% from SPIRIT 1 and 43% from SPIRIT 2). Women taking relugolix combination therapy had less pelvic or groin pain during and between menstrual periods within 4 weeks of starting the medicine. The most common side effects were headaches, the common cold, and hot flushes or feeling hot among women taking relugolix combination therapy, delayed relugolix combination therapy, and placebo. Relugolix combination therapy was considered safe for those with no major medical problems. Women taking relugolix combination therapy had little to no loss of bone mineral density (a way of knowing how strong bones are) after 24 weeks of treatment.</p><p><strong>What do the results of these studies tell us?: </strong>Women with moderate to severe endometriosis taking relugolix combination therapy had much less pain from endometriosis than women taking placebo. <b>Clinical Trial Registration</b>: NCT03204318 (SPIRIT-1); NCT03204331 (SPIRIT-2) (ClinicalTrials.gov).</p>","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"631-640"},"PeriodicalIF":1.7,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138047719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identifying patient and clinician-centered strategies to improve access to integrative care for patients with chronic pain","authors":"Sebastian Tong, Marshall Brooks, Karissa Tu, Wu-Hsun Tom Yang","doi":"10.1370/afm.22.s1.4662","DOIUrl":"https://doi.org/10.1370/afm.22.s1.4662","url":null,"abstract":"","PeriodicalId":20000,"journal":{"name":"Pain management","volume":"231 1 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139299987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Peripheral nerve block adjuncts: which medication to choose? A narrative review of the current literature.","authors":"Robert Vietor, Roland Kiendrebeogo, Erin Tracy, Anthony R Plunkett","doi":"10.2217/pmt-2023-0049","DOIUrl":"10.2217/pmt-2023-0049","url":null,"abstract":"<p><p>Enhancing the effect of peripheral nerve blockade by adding other classes of medications has long history of trial and error. Studies have identified multiple potentially beneficial adjuncts that work to either speed the onset of analgesia or prolong its duration. The benefits of these adjuncts must be weighed against the risks of systemic negative side effects. To date, the most commonly used adjuncts, and ones with the most robust scientific efficacy are, dexamethasone, dexmedetomidine and buprenorphine. This narrative review will discuss several classes of local anesthetic adjuncts and provide evidence for the clinical efficacy and side effect profile of the most commonly studied medications.</p>","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"655-665"},"PeriodicalIF":1.7,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71484917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spinal cord stimulation for visceral pain associated with medullary sponge kidney.","authors":"Naveed S Noordin, Cody J Cox, Michael M Wilkinson, Eellan Sivanesan, Yian Chen","doi":"10.2217/pmt-2023-0075","DOIUrl":"10.2217/pmt-2023-0075","url":null,"abstract":"<p><p>Chronic pain is a common reason for which people in the USA seek medical care. It is linked to opioid consumption, anxiety and a reduction in quality of life. Over the past 50 years, spinal cord stimulation (SCS) has evolved as a safe and efficacious treatment for chronic pain etiologies. The authors present the first known case of SCS for pain due to medullary sponge kidney disease. This report adds to the growing body of literature supporting the use of SCS for treating visceral organ pain, while also highlighting the utility of ventral lead placement for treating visceral pain. As SCS utilization increases, it is expected that there will be a decrease in opioid consumption, and this will help us contain the opioid epidemic.</p>","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"641-646"},"PeriodicalIF":1.7,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71484919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Peripheral nerve stimulation for chronic knee pain following total knee arthroplasty: a systematic review.","authors":"Edwin Amirianfar, Richard Rosales, Andrew Logan, Tina L Doshi, John Reynolds, Chane Price","doi":"10.2217/pmt-2023-0057","DOIUrl":"10.2217/pmt-2023-0057","url":null,"abstract":"<p><p>Chronic knee pain following total knee arthroplasty (TKA) affects a subset of patients that is refractory to pharmacological and non-pharmacological modalities. Peripheral nerve stimulation (PNS) has been used in patients with chronic knee pain following TKA and has shown some efficacy. <b>Methods:</b> Comprehensive search of Ovid Medline, Elsevier Embase, Cochrane Central Register of Controlled Trials, CINAHL Plus with Full Text, Scopus, SPORTDiscus with Full Text and the Web of Science platform. From inception to August 2022, for studies using PNS to treat chronic knee pain following TKA. Primary outcomes included pain scores, functional status and medication usage. <b>Results:</b> Nine studies were extrapolated with all demonstrating effectiveness of PNS for patients with chronic knee pain following TKA. <b>Discussion:</b> PNS for chronic knee pain following TKA has been shown to be an efficacious treatment modality. The level of evidence is low and more research is needed to assess its safety and effectiveness.</p>","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"667-676"},"PeriodicalIF":1.7,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71484918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of Opioid Policies in 8 Health Systems: Findings from a Mixed-Methods Implementation & Effectiveness Study","authors":"Sarah J. Shoemaker-Hunt, Zoe Pringle, Elizabeth Ciemins, Jaswinder Legha, Lisanne Brown, John Le, Christina Mikosz, S. Radakrishnan, Leigh Mathias","doi":"10.1370/afm.22.s1.4781","DOIUrl":"https://doi.org/10.1370/afm.22.s1.4781","url":null,"abstract":"","PeriodicalId":20000,"journal":{"name":"Pain management","volume":"14 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139296353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Family Emotional Climate: Risk or Resilience Factor for Pain Development Among Aging African Americans","authors":"Sarah Woods, Patricia Roberson","doi":"10.1370/afm.22.s1.5426","DOIUrl":"https://doi.org/10.1370/afm.22.s1.5426","url":null,"abstract":"","PeriodicalId":20000,"journal":{"name":"Pain management","volume":"61 1","pages":""},"PeriodicalIF":1.7,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139295925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}