Pain managementPub Date : 2025-05-01Epub Date: 2025-05-20DOI: 10.1080/17581869.2025.2508680
Masataka Umeda, Youngdeok Kim
{"title":"The role of anxiety in the association between physical pain and social pain sensitivity in young adults.","authors":"Masataka Umeda, Youngdeok Kim","doi":"10.1080/17581869.2025.2508680","DOIUrl":"10.1080/17581869.2025.2508680","url":null,"abstract":"<p><strong>Background: </strong>We experience physical pain and social pain. While rejection sensitivity measures, such as Brief Fear of Negative Evaluation Scale (BFNES), were previously used to evaluate social pain sensitivity, Social Pain Questionnaire (SPQ) has been developed to specifically evaluate social pain sensitivity. Although physical pain and social pain seem quite distinct from each other, research shows a close link between them. However, the association between physical pain sensitivity and SPQ remains unclear. This study examined the association of SPQ with BFNES and Pain Sensitivity Questionnaire (PSQ), an instrument to evaluate physical pain sensitivity, and involvement of anxiety in the association between physical pain and social pain sensitivity.</p><p><strong>Methods: </strong>One-hundred forty young adults participated in this cross-sectional survey study and completed the general information questionnaire, PSQ, BFNES, SPQ, and Trait Anxiety Inventory (TAI). Data were analyzed using correlation and partial correlation analyses.</p><p><strong>Results: </strong>SPQ was associated with both PSQ and BFNES, while TAI was associated with PSQ, BFNES, and SPQ. The association between PSQ and BFNES remained significant after controlling TAI, but the association between PSQ and SPQ disappeared.</p><p><strong>Conclusion: </strong>The results demonstrate convergent validity of SPQ in pain. Anxiety may explain the association between physical pain and social pain sensitivity.</p>","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"259-264"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118422/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144110882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain managementPub Date : 2025-05-01Epub Date: 2025-04-29DOI: 10.1080/17581869.2025.2494975
Isabel Patricia Serrano, Daniel Wang, Rochelle Angelica A Saratan, Melecio Iii Peña, Jeimylo C de Castro
{"title":"Dextrose-based Lyftogt perineural injection therapy on facial muscle strength in a Bell's palsy patient - a case report.","authors":"Isabel Patricia Serrano, Daniel Wang, Rochelle Angelica A Saratan, Melecio Iii Peña, Jeimylo C de Castro","doi":"10.1080/17581869.2025.2494975","DOIUrl":"10.1080/17581869.2025.2494975","url":null,"abstract":"<p><p>Bell's palsy, a unilateral peripheral facial nerve palsy, is one of the most common acute mononeuropathies. Chronic cases persisting beyond one year present significant challenges to conventional treatment methods. Standard treatment includes steroids and antiviral medications in the acute phase, and physical therapy, various supplements such as vitamin B12 and folic acid supplementation, and injections for chronic therapy. This case report describes the effect of a unique treatment, dextrose-based Lyftogt perineural injection therapy (LPIT), in a 22-year-old Filipino male with left-sided peripheral facial nerve palsy. His condition had persisted for a duration of 13 months and was refractory to standard management. LPIT was delivered at chronic constriction points and endpoints of the facial nerve in ten different sessions. The mechanism of LPIT involves addressing glycopenia in affected nerves, reducing neurogenic inflammation, and facilitating nerve repair by enhancing the flow of nerve growth factors. Following treatment, marked improvement was observed in the functional muscle strength of the left occipitofrontalis, zygomaticus, and buccinator muscles, progressing from weak functional to functional. This case underscores LPIT's potential as an adjunct therapy for chronic Bell's palsy, adding to the limited but a growing body of evidence supporting its role in managing neuropathic conditions.</p>","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"245-250"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118416/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144008806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain managementPub Date : 2025-05-01Epub Date: 2025-04-25DOI: 10.1080/17581869.2025.2494978
Ogochukwu Izuegbuna, Israel Kolawole, Saliu Oguntola, Tiwalade Woods-Ali, Oyewale Saburi, Chijioke Chijindu Adindu, Samuel Olatoke, Olawale Adebayo Olakulehin
{"title":"Prevalence and factors associated with cancer-related neuropathic pain among cancer patients in Nigeria - a single-center cross-sectional study.","authors":"Ogochukwu Izuegbuna, Israel Kolawole, Saliu Oguntola, Tiwalade Woods-Ali, Oyewale Saburi, Chijioke Chijindu Adindu, Samuel Olatoke, Olawale Adebayo Olakulehin","doi":"10.1080/17581869.2025.2494978","DOIUrl":"10.1080/17581869.2025.2494978","url":null,"abstract":"<p><strong>Objectives: </strong>Neuropathic pain is a major challenge in supportive care management among cancer patients. This study aims to evaluate neuropathic pain in Nigerian cancer patients.</p><p><strong>Methods: </strong>This is a cross-sectional study with 126 cancer patients recruited from the University of Ilorin Teaching Hospital and are 18 years and above. Medical records were collected from their medical files and the patients. The painDETECT questionnaire (PDQ) and the numeric rating scale (NRS) were used to determine the level and form pain.</p><p><strong>Results: </strong>Neuropathic pain in the target populace of cancer patients was 23% in prevalence. The mean age of the cancer patients in the study was 53 years; 69.8% were females. A considerable association was seen between neuropathic pain and performance status (<i>p</i> < 0.001), morphine and pregabalin use (<i>p</i> < 0.001). Binary logistic regression analysis, performance status (b = 18.00, <i>p</i> = 0.009) and use of morphine (b = 11.52, <i>p</i> < 0.001) and pregabalin (b = 18.09, <i>p</i> < 0.001) were significantly associated with neuropathic pain. Performance status, and morphine use (<i>p</i> < 0.001) were associated with pain severity.</p><p><strong>Discussion: </strong>This being the first study in Nigeria, neuropathic pain incidence in Nigerian cancer patients is a work in progress. Performance status and some pain modifiers are predictors of neuropathic pain in Nigerian cancer patients.</p>","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"251-258"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118389/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144007283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Head-to-head relief: ubrogepant, rimegepant, and zavegepant in migraine treatment.","authors":"Lanfranco Pellesi, Budour Jedie, Fadia Barhum, Samah Al-Abdullah, Paolo Martelletti, Zheman Xiao","doi":"10.1080/17581869.2025.2494494","DOIUrl":"10.1080/17581869.2025.2494494","url":null,"abstract":"<p><p>Migraine, a significant cause of disability worldwide, heavily impacts daily functioning and quality of life. Despite various acute treatment options, including nonsteroidal anti-inflammatory drugs (NSAIDs) and triptans, patients experience limited relief or adverse effects. This review examines the efficacy and safety of gepants - ubrogepant, rimegepant, and zavegepant - in the acute treatment of migraine. We assessed phase II and III clinical trials, focusing on clinically relevant endpoints such as pain freedom and freedom from the most bothersome symptom at two hours post-treatment. We calculated the number needed to treat (NNT) to achieve significant endpoints for each gepant. Gepants are recommended for the acute treatment of migraine in individuals who do not respond to triptan monotherapy or combination therapy, who experience only partial effectiveness, or who cannot tolerate or have contraindications to triptans. The NNT values for achieving pain freedom at two hours were 9 for rimegepant, 11 for zavegepant, and 12 for ubrogepant, which are comparable to NSAIDs such as naproxen (NNT = 11). Paracetamol, although not an NSAID, showed similar efficacy (NNT = 12). Triptans demonstrated lower NNTs, indicating higher efficacy. Gepants offer effective, well-tolerated alternatives with no significant cardiovascular risk and minimal potential for medication-overuse headache.</p>","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"279-284"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118443/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144036773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain managementPub Date : 2025-05-01Epub Date: 2025-05-21DOI: 10.1080/17581869.2025.2507562
Francine Toye
{"title":"\"Who is this 'I' who speaks?\" - what can the Arts teach us about pain?","authors":"Francine Toye","doi":"10.1080/17581869.2025.2507562","DOIUrl":"10.1080/17581869.2025.2507562","url":null,"abstract":"","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"231-233"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118387/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144111703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain managementPub Date : 2025-05-01Epub Date: 2025-04-17DOI: 10.1080/17581869.2025.2493609
Lisa R LaRowe, Tony Pham, Claire Szapary, Ana-Maria Vranceanu
{"title":"Shaping the future of geriatric chronic pain care: a research agenda for progress.","authors":"Lisa R LaRowe, Tony Pham, Claire Szapary, Ana-Maria Vranceanu","doi":"10.1080/17581869.2025.2493609","DOIUrl":"10.1080/17581869.2025.2493609","url":null,"abstract":"<p><p>Chronic pain is highly prevalent among older adults and its burden will become increasingly significant as our population ages. Yet, chronic pain is often undertreated in this vulnerable population due to various barriers in health care delivery. To improve geriatric chronic pain management, we assert that older adults require a dedicated research agenda designed to inform the development, testing, and implementation of chronic pain treatments that account for the unique vulnerabilities and healthcare needs of this population. Specifically, we propose that the following four areas of research require immediate attention to better serve older adults with chronic pain: (1) health equity, (2) substance use, (3) dyadic interventions, and (4) digital health. Our proposed research agenda aims to create a more robust and comprehensive body of evidence that will ultimately transform and advance geriatric chronic pain management.</p>","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"265-277"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118399/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144031166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain managementPub Date : 2025-04-01Epub Date: 2025-04-10DOI: 10.1080/17581869.2025.2490466
Marc Caragea, Matthew Essman, Aaron Conger, Noah Quinlan, Peter Chalmers, Zachary McCormick
{"title":"Management of post-arthroplasty pain: a narrative review of emerging interventional treatments.","authors":"Marc Caragea, Matthew Essman, Aaron Conger, Noah Quinlan, Peter Chalmers, Zachary McCormick","doi":"10.1080/17581869.2025.2490466","DOIUrl":"10.1080/17581869.2025.2490466","url":null,"abstract":"<p><p>Total joint arthroplasties are one of the most common orthopedic procedures with over 1 million total hip and knee arthroplasties performed annually. While the majority of patients experience favorable long-term outcomes, a significant number of patients continue to report persistent pain more than 3 months post-arthroplasty that is unresponsive to conservative treatment. Although current treatment options may seem limited, there are a variety of innovative procedures for the management of post-arthroplasty pain with the overall goal of reducing pain and restoring function. In this review, we outline the work-up for persistent post-arthroplasty pain and provide a review of the literature on interventional treatment modalities consisting of intra-articular steroids, radiofrequency ablation, and neuromodulation for the management of chronic post-arthroplasty pain in the hip, knee, ankle, and shoulder.</p>","PeriodicalId":20000,"journal":{"name":"Pain management","volume":"15 4","pages":"213-226"},"PeriodicalIF":1.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12054930/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144028301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain managementPub Date : 2025-04-01Epub Date: 2025-04-03DOI: 10.1080/17581869.2025.2487408
Tania Gardner, Christine T Shiner, Alison Mahoney, Henry Loui, Marnee McKay
{"title":"Pain patterns and their association with psychological measures among people accessing an online pain management program.","authors":"Tania Gardner, Christine T Shiner, Alison Mahoney, Henry Loui, Marnee McKay","doi":"10.1080/17581869.2025.2487408","DOIUrl":"10.1080/17581869.2025.2487408","url":null,"abstract":"<p><strong>Aim: </strong>This study aimed to explore the association between the distribution of pain sites and psychosocial measures at baseline of patients enrolled in an online MPMP.</p><p><strong>Patients: </strong>This study analyzed baseline data from adults (<i>N</i> = 2002) enrolled in the 'Reboot Online' pain program.</p><p><strong>Methods: </strong>Participants completed measures of Pain Self-Efficacy Questionnaire (PSEQ), Tampa Scale for Kinesiophobia (TSK), Pain Disability Index (PDI), Patient Health Questionnaire (PHQ-9), and Kessler Psychological Distress Scale (K-10). Pain was categorized by the number of body regions affected: 1, 2, 3, >3. One-way ANOVA tests examined psychosocial measure differences across these groups.</p><p><strong>Results: </strong>The majority of participants had multisite pain, with multisite pain showing significantly worse psychosocial outcome measures (<i>p</i> < .05) compared to those with a single pain site, except for kinesiophobia, which was consistently high across groups.</p><p><strong>Conclusion: </strong>Most online participants reported multisite pain, with multisite pain associated with poorer baseline psychosocial outcome measures, excluding kinesiophobia. The pattern of pain should be considered when developing and implementing online programs.</p>","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"205-212"},"PeriodicalIF":1.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12001539/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143772356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain managementPub Date : 2025-04-01Epub Date: 2025-03-02DOI: 10.1080/17581869.2025.2473871
Sanne A M Hendrickx, Ellie B M Landman, Ydo V Kleinlugtenbelt
{"title":"Post-discharge opioid utilization patterns in orthopedic patients are underestimated: an explorative study.","authors":"Sanne A M Hendrickx, Ellie B M Landman, Ydo V Kleinlugtenbelt","doi":"10.1080/17581869.2025.2473871","DOIUrl":"10.1080/17581869.2025.2473871","url":null,"abstract":"<p><strong>Aim: </strong>This study explores morphine use among patients after discharge following total hip (THA) or knee arthroplasty (TKA).</p><p><strong>Method: </strong>Morphine use was monitored for 14 days post-discharge. Patients recorded their morphine intake and reported pain using a Visual Analog Scale (VAS). Incomplete reports were excluded from longitudinal analysis. Median tablet count and total morphine use in milligram equivalents (MME) were calculated. Patients were categorized as non-users (0 mmE), short-term users (<100 mmE), and consistent users (>100 mmE).</p><p><strong>Results: </strong>Of the 67 patients, six dropped out. Among the remaining, 22 (36.7%) took no morphine, while 38 (63.3%) took at least one dose, with a median VAS-score of 5. Short-term users (<i>n</i> = 19) averaged a total of 40 mmE, mainly in the first three days, while consistent users (<i>n</i> = 15) averaged in total 220 mmE during follow-up, tapering gradually. After 14 days, 3% continued usage. Four patients with incomplete data were excluded. However, for those was found that this was due to or related to the fact that they used a large amount of morphine.</p><p><strong>Conclusion: </strong>Most patients used minimal or no morphine, tapering off within two weeks.</p>","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"199-204"},"PeriodicalIF":1.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12001552/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143537525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}