Pain management最新文献_第5页

The Johns Hopkins multidisciplinary pediatric pain management service: a concept paper. 约翰霍普金斯多学科儿科疼痛管理服务：概念论文。

IF 1.5

Pain management Pub Date : 2025-09-01 Epub Date: 2025-07-13 DOI: 10.1080/17581869.2025.2532356

M-Irfan Suleman, Ama Akoma Essuman, Maqbool Dada, Kayode Williams

{"title":"The Johns Hopkins multidisciplinary pediatric pain management service: a concept paper.","authors":"M-Irfan Suleman, Ama Akoma Essuman, Maqbool Dada, Kayode Williams","doi":"10.1080/17581869.2025.2532356","DOIUrl":"10.1080/17581869.2025.2532356","url":null,"abstract":"Chronic pain in children poses a significant and under-addressed public health burden. This concept paper outlines the proposed design and implementation of a Multidisciplinary Pediatric Pain Management Service (MPPMS) at Johns Hopkins Medicine, addressing four key objectives. First, it presents a novel care delivery model grounded in the biopsychosocial framework, led by a multidisciplinary team and structured to deliver patient-centered care across escalating levels of clinical intensity. Second, it details the operationalization of the clinic in three phases, starting with a lean model and scaling toward a transdisciplinary team structure through enhanced clinic efficiency, technology integration, and strategic resource allocation. Third, it examines the financial implications of the model, including cost-per-encounter estimates, phased improvements in resource utilization, and strategies for achieving long-term sustainability through alternative revenue streams and workflow optimization. Fourth, it proposes a comprehensive outcomes framework encompassing clinical, operational, and financial metrics to guide continuous improvement and facilitate national benchmarking. Collectively, this paper provides a scalable blueprint for managing pediatric chronic pain that integrates care, optimizes operations, ensures fiscal responsibility, and delivers measurable patient benefit, positioning the MPPMS as a model that can be replicated at other institutions to address this growing clinical need.","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"587-593"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fremanezumab for the treatment of migraine. Fremanezumab用于治疗偏头痛。

IF 1.5

Pain management Pub Date : 2025-09-01 DOI: 10.1080/17581869.2025.2550923

Dimos Mitsikostas, Srdjan Ljubisavljevic

{"title":"Fremanezumab for the treatment of migraine.","authors":"Dimos Mitsikostas, Srdjan Ljubisavljevic","doi":"10.1080/17581869.2025.2550923","DOIUrl":"https://doi.org/10.1080/17581869.2025.2550923","url":null,"abstract":"Fremanezumab is a monoclonal antibody inhibiting the CGRP signaling leading to migraine prophylaxis. Its efficacy and potential safety concerns are updated here. All available data on fremanezumab were searched in PubMed with emphasis on the mechanisms of action, efficacy, tolerability, and safety. There is class I evidence for the efficacy of fremanezumab in the prophylaxis of both EM and CM, by reducing 1 to 2 monthly migraine days over placebo, but in real-world studies the magnitude of efficacy was greater. Though the size of efficacy looks like that of some repurposed anti-migraine treatments, its excellent tolerably highly improves the likelihood to help versus harm outcome over all traditional medications. Fremanezumab works in people with migraine and medication overuse, in people with previous treatment failures, as well as in people with concomitant depression, improving both migraine and depression measures. The latest data, along with the recent approval for use in children and adolescents, are unique among all migraine treatments. Alone or in combination with botulinumtoxin A may improve resistance to migraine. Mild reactions at the injection site are the most common side effects. Thus, fremanezumab represents an optimal treatment for people with migraine and should be considered as first-line choice.","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"1-10"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144964673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Virtual reality in chronic pain management: how do we galvanize a stagnant field? 慢性疼痛管理中的虚拟现实：我们如何激发一个停滞的领域？

IF 1.5

Pain management Pub Date : 2025-08-29 DOI: 10.1080/17581869.2025.2554561

Carly L A Wender, Zina Trost

引用次数: 0

Recovery indicators from the perspective of patients with chronic low back pain: a cross-sectional survey. 慢性腰痛患者康复指标的横断面调查

IF 1.5

Pain management Pub Date : 2025-08-28 DOI: 10.1080/17581869.2025.2552631

Razieh Javadian Kootenayi, Razieh Mofateh, Maryam Seyedtabib

{"title":"Recovery indicators from the perspective of patients with chronic low back pain: a cross-sectional survey.","authors":"Razieh Javadian Kootenayi, Razieh Mofateh, Maryam Seyedtabib","doi":"10.1080/17581869.2025.2552631","DOIUrl":"https://doi.org/10.1080/17581869.2025.2552631","url":null,"abstract":"Aims: In low back pain (LBP) research, recovery is commonly used as an outcome measure. However, there is no method used to measure recovery or acceptable definition for recovery. This research aims to investigate patients' perceptions of recovery from LBP.Materials & methods: A cross-sectional survey was conducted in which 350 patients with chronic LBP participated. Demographic and clinical information was collected by a comprehensive and inclusive questionnaire. A checklist of improvement indicators was given to the patients and completed by them. It was aimed to identify the most important criteria for recovery in patients with chronic LBP.Results: The results showed that pain reduction alone is not a reliable indicator of recovery. The patients' view about the recovery from chronic LBP includes a wide range of factors in different areas of symptomatic improvement, fear of recurrence injury, functional disability, fatigue and reduced energy level. Also, a significant correlation was observed between recovery indicators and pain duration, body mass index, and pain intensity in patients with chronic LBP.Conclusions: The framework of recovery for patients with chronic LBP is complicated and is a highly individual structure. It is determined by the impact of symptoms on activities of daily living factors.","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"1-9"},"PeriodicalIF":1.5,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144964671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of dual direct and alternating currents on pain induced by blood sampling and intramuscular injection processes. 直流和交流双电流对采血和肌内注射过程引起的疼痛的影响。

IF 1.5

Pain management Pub Date : 2025-08-13 DOI: 10.1080/17581869.2025.2544525

Ebrahim Ezzati, Roghaye Mahooti, Saeed Mohammadi, Rasoul Kavyannejad

{"title":"Effect of dual direct and alternating currents on pain induced by blood sampling and intramuscular injection processes.","authors":"Ebrahim Ezzati, Roghaye Mahooti, Saeed Mohammadi, Rasoul Kavyannejad","doi":"10.1080/17581869.2025.2544525","DOIUrl":"https://doi.org/10.1080/17581869.2025.2544525","url":null,"abstract":"Objective: This study investigates the effects of cathodal, anodal, and intermittent electrical stimulation on pain intensity associated with arterial blood sampling, venous blood sampling, and intramuscular injection.Methods: In a triple-blind clinical trial, 160 patients requiring arterial, venous blood sampling, and intramuscular injection were randomly divided into four groups. Three intervention groups received 5 mA anodal, cathodal direct, or alternating currents during the procedure, while the control group received only a topical eutectic mixture of local anesthetics (EMLA). Pain intensity was measured using the visual analog scale (VAS) immediately after the procedure, while procedure duration, number of attempts, and heart rate changes were recorded as secondary outcome.Results: All forms of electrical stimulation significantly reduced procedural pain compared to EMLA. Cathodal direct current demonstrated the greatest analgesic effect, with mean VAS score reductions of 2-3 points across all procedures. The time required for arterial blood sampling in the cathodal group was significantly less than with EMLA, while no difference was observed in the procedure time and frequency of attempts in other processes. Furthermore, electrical stimulation groups, particularly the cathodal mode, exhibited lower post-procedure heart rates, suggesting attenuated physiological stress responses.Conclusion: We found that applying electric currents during the procedure reduces the pain of blood sampling or injections. The greatest analgesia was observed with cathodal direct current stimulation compared to other groups.Clinical trial registration: Date of registration: 27 January 2024. Clinical Trials.gov Identifier: IRCT20240123060780N1. URL: https://irct.behdasht.gov.ir/trial/75119.","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"1-12"},"PeriodicalIF":1.5,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144837295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Artificial intelligence-enhanced pain management: the NXTSTIM EcoAI platform. 人工智能增强疼痛管理：NXTSTIM EcoAI平台。

IF 1.5

Pain management Pub Date : 2025-08-01 Epub Date: 2025-07-01 DOI: 10.1080/17581869.2025.2527575

Maja Green, Krishnan Chakravarthy

{"title":"Artificial intelligence-enhanced pain management: the NXTSTIM EcoAI platform.","authors":"Maja Green, Krishnan Chakravarthy","doi":"10.1080/17581869.2025.2527575","DOIUrl":"10.1080/17581869.2025.2527575","url":null,"abstract":"Chronic pain affects approximately 20% of the global population, leading to significant disability and economic burden. Traditional management strategies, including pharmacologic interventions and physical therapies, often provide limited relief and are associated with adverse effects. Non-invasive neuromodulation techniques, such as transcutaneous electrical nerve stimulation (TENS) and electrical muscle stimulation (EMS), have shown promise but are hindered by issues like inconsistent dosing and poor adherence. The integration of artificial intelligence (AI) into pain management offers a novel approach to personalize and optimize therapy. The NXTSTIM EcoAI platform exemplifies this innovation by combining TENS and EMS with machine learning (ML) algorithms, cloud-based analytics, and remote patient monitoring (RPM). This closed-loop system dynamically adjusts stimulation parameters based on real-time patient data, enhancing efficacy and user engagement. By continuously learning from individual responses and aggregated trends, EcoAI aims to provide tailored pain relief while addressing the limitations of conventional neuromodulation devices. This review explores the current landscape of pain management, the mechanisms of electrostimulation analgesia, and the potential of AI-driven digital therapeutics like EcoAI to revolutionize chronic pain treatment.","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"467-475"},"PeriodicalIF":1.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12320875/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144541847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Predictive factors of epidural rescue in combined spinal-epidural anesthesia for cesarean delivery. 剖宫产腰硬联合麻醉硬膜外抢救的预测因素。

IF 1.5

Pain management Pub Date : 2025-08-01 Epub Date: 2025-07-05 DOI: 10.1080/17581869.2025.2526318

Kaissar Sassi, Juliette Linval, Etienne Bechet, Nancy El Achkar, Elsa Tardif, Vincent Minville

{"title":"Predictive factors of epidural rescue in combined spinal-epidural anesthesia for cesarean delivery.","authors":"Kaissar Sassi, Juliette Linval, Etienne Bechet, Nancy El Achkar, Elsa Tardif, Vincent Minville","doi":"10.1080/17581869.2025.2526318","DOIUrl":"10.1080/17581869.2025.2526318","url":null,"abstract":"Background: Combined spinal-epidural (CSE) is often recommended for cesarean deliveries expected to have prolonged duration. This study aimed to identify factors associated with the need for epidural rescue anesthesia during CSE for cesarean section, to better refine clinical indications for this technique.Methodology: This retrospective cohort study was conducted from 2020 to 2022 at the maternity of Toulouse University Hospital, France. Data were collected from 230 patients who underwent CSE for cesarean delivery. The mean age was 34.3 ± 5.6 years, 69.1% had previous cesarean sections, and 70% had a BMI > 24.9. Univariate analysis identified potential predictors, which were then included in multivariate logistic regression to determine independent factors associated with epidural rescue.Results: The overall rate of rescue epidural anesthesia was 16.5% (38/230). Multivariate analysis identified three independent predictors: gestational diabetes (adjusted odds ratio [aOR] 2.39, 95% CI: 1.07-5.29, p = 0.032), postpartum hemorrhage ≥ 500 mL (aOR 2.29, 95% CI: 1.35-3.90, p = 0.002), and surgical duration ≥ 62 minutes (aOR 4.36, 95% CI: 1.99-9.58, p < 0.001).Conclusion: Gestational diabetes, postpartum hemorrhage, and surgical duration exceeding 62 minutes significantly increase the likelihood of epidural rescue during CSE for cesarean delivery. These findings could guide more selective CSE use, potentially avoiding unnecessary epidural catheter placement in low-risk situations.","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"501-508"},"PeriodicalIF":1.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12320873/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144567688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Citrus Aurantium L. on pain and blood pressure in patients undergoing hand reconstructive surgery. 枳实对手部再造术患者疼痛和血压的影响。

IF 1.5

Pain management Pub Date : 2025-08-01 Epub Date: 2025-07-06 DOI: 10.1080/17581869.2025.2515814

Farideh Askari, Farzaneh Ghaffari, Nasrin Alaee, Mohsen Naseri, Akram Tayanloo-Beik

{"title":"Effect of Citrus Aurantium L. on pain and blood pressure in patients undergoing hand reconstructive surgery.","authors":"Farideh Askari, Farzaneh Ghaffari, Nasrin Alaee, Mohsen Naseri, Akram Tayanloo-Beik","doi":"10.1080/17581869.2025.2515814","DOIUrl":"10.1080/17581869.2025.2515814","url":null,"abstract":"Background and purpose: Postoperative pain and blood pressure are common patient complaints. This study examined the effects of Citrus Aurantium (CA) on pain and blood pressure in patients undergoing hand reconstructive surgery.Methods: A double-blind, randomized clinical trial was conducted with 76 patients. The control group received a placebo, while the intervention group received CA essential oil. Blood pressure and pain levels were recorded before the intervention, and at 30 minutes and one-hour post-surgery. Data collection used blood pressure sheets, numerical visual pain scales, and demographic questionnaires.Result: The intervention group showed significantly greater pain reduction than the control group (p = 0.001), with CA increasing the likelihood of pain reduction by 1.73 times (Exp(B) = 1.73). Systolic and diastolic blood pressure significantly decreased post-intervention (p = 0.001, p = 0.005), but differences were not significant after 30 minutes and one hour after (p > 0.05). CA increased the likelihood of systolic blood pressure reduction by 16.87 times (Exp(B) = 16.78), with no effect on diastolic pressure.Conclusion: CA facilitates pain and blood pressure reduction in aromatherapy, suggesting its use as a simple, inexpensive, and noninvasive method for postoperative pain management.","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"491-500"},"PeriodicalIF":1.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12320857/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144576101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ankylosing spondylitis management: a narrative review of radiofrequency ablation and naproxen. 强直性脊柱炎的治疗：射频消融和萘普生的叙述性回顾。

IF 1.5

Pain management Pub Date : 2025-08-01 Epub Date: 2025-06-11 DOI: 10.1080/17581869.2025.2518046

Akash Patel, Dev Patel, John DesRochers, Abdullah Noory, Brandon Goodwin, Don D Shamilov, David F Lo, Richard Jermyn

{"title":"Ankylosing spondylitis management: a narrative review of radiofrequency ablation and naproxen.","authors":"Akash Patel, Dev Patel, John DesRochers, Abdullah Noory, Brandon Goodwin, Don D Shamilov, David F Lo, Richard Jermyn","doi":"10.1080/17581869.2025.2518046","DOIUrl":"10.1080/17581869.2025.2518046","url":null,"abstract":"Axial spondyloarthritis (axSpA) is a chronic inflammatory disease primarily affecting the spine and sacroiliac joints, causing pain, stiffness, and reduced mobility. Its pathophysiology remains unclear, complicating treatment development. Management aims to alleviate symptoms and control inflammation, but targeted strategies are lacking. This study compared the efficacy of radiofrequency ablation (RFA) and naproxen in axSpA treatment. A PubMed search was conducted on 14 March 2023 and 27 May 2025. RFA is a minimally invasive procedure that targets nerve endings to block pain signals, while naproxen is a non-steroidal anti-inflammatory drug (NSAID) that reduces inflammation. We conducted a narrative review of axSpA patients treated with either RFA or naproxen, assessing pain relief, functional improvement, and quality of life. Results showed that RFA was significantly more effective than naproxen in managing chronic pain. Patients receiving RFA reported greater pain reduction and better functional outcomes compared to those on naproxen. RFA provided prolonged relief, while naproxen's effectiveness diminished over time, limiting its long-term benefit. These findings suggest that RFA should be considered a preferred treatment for axSpA patients seeking long-term pain relief and improved quality of life. This study supports RFA's role in managing inflammatory spinal conditions and informs optimal axSpA treatment strategies.","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"519-526"},"PeriodicalIF":1.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12320818/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy of temporo-parietal fascia trigger point release in the management of tension-type headache: a single-blinded RCT. 颞顶筋膜触发点释放治疗紧张性头痛的疗效：单盲随机对照试验。

IF 1.5

Pain management Pub Date : 2025-08-01 Epub Date: 2025-07-12 DOI: 10.1080/17581869.2025.2527616

Sandhya Shrivastav, Sneha Mittal, Sunita Sharma, Amit Kumar

{"title":"Efficacy of temporo-parietal fascia trigger point release in the management of tension-type headache: a single-blinded RCT.","authors":"Sandhya Shrivastav, Sneha Mittal, Sunita Sharma, Amit Kumar","doi":"10.1080/17581869.2025.2527616","DOIUrl":"10.1080/17581869.2025.2527616","url":null,"abstract":"Background: The study aimed to investigate the effects of Temporoparietal Fascia trigger point release in subjects with Tension Type Headache (TTH) and on decreasing pain intensity and head and neck disability.Methods: 40 subjects were randomly assigned to either Group 1 (intervention group) or Group 2 (control group) and received treatment for 10 days. Outcome measures, including the Visual Analog Scale (VAS) for pain intensity, Neck Disability Index (NDI) for neck disability, Headache Disability Inventory (HDI) for headache disability, and Pressure Pain Threshold (PPT) were used. Assessments were conducted in both groups before and after the 10-day intervention period.Result: Both groups exhibited statistically significant improvements in pain intensity, neck and headache disability, and pressure pain threshold after 10 days of intervention (p = 0.001). However, the intervention group showed greater clinical improvement compared to the control group. Between-group analysis revealed significant differences favoring the intervention group in VAS (t = 10.63), NDI (t = 7.81), HDI (t = 8.00), and PPT (t = 2.60), indicating that trigger point release in the temporo-parietal fascia was more effective in reducing symptoms and enhancing pain threshold.Conclusion: The study concluded that Myofascial trigger points (MTrPs) release is notably effective in pain reduction, as evidenced by greater clinical improvement in the intervention group compared to the control group. Both groups experienced similar benefits in reducing head and neck-related disabilities and increasing pain pressure thresholds.Clinical trial registration: www.ctri.nic.in, identifier: CTRI/2023/06/054085.","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"509-517"},"PeriodicalIF":1.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12320840/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144619690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0