Pain managementPub Date : 2024-10-01Epub Date: 2024-11-27DOI: 10.1080/17581869.2024.2432852
Julie R Brewer, Katherine A McDermott, Jonathan Greenberg, Alexander M Presciutti, Danielle E LaCamera, Christine S Ritchie, Ana-Maria Vranceanu
{"title":"Patient and staff perspectives on pain treatment experiences in a community clinic serving under-resourced older adults.","authors":"Julie R Brewer, Katherine A McDermott, Jonathan Greenberg, Alexander M Presciutti, Danielle E LaCamera, Christine S Ritchie, Ana-Maria Vranceanu","doi":"10.1080/17581869.2024.2432852","DOIUrl":"10.1080/17581869.2024.2432852","url":null,"abstract":"<p><strong>Aims: </strong>Chronic pain affects up to 37.8% of older adults with higher prevalence among those in under-resourced communities. While there are many treatments for chronic pain, there are complexities to treating under-resourced older adults in community clinics, including multimorbidity, barriers to treatment access, and varying degrees of openness to different treatment approaches. Understanding patient and clinic staff perceptions of treatment options for chronic pain is critical for implementing treatment approaches that will work sustainably in the community. This study aimed to understand clinic staff and patients' perspectives on chronic pain treatment experiences.</p><p><strong>Methods: </strong>Focus groups and individual interviews were analyzed using a hybrid inductive-deductive approach.</p><p><strong>Results: </strong>Themes are: (1) Limited patient and clinic resources and availability affecting pain treatment experiences (e.g., copays, transportation challenges, and conflicting responsibilities), (2) Discrepancies in patient and staff approaches to treatment and the importance of trialing different pain management techniques to alleviate pain (e.g., trialing multiple treatments with varied success), and (3) Conflict between patients' desire for pain elimination vs. staffs' focus on symptom reduction and function (e.g., patient-staff disconnect).</p><p><strong>Conclusions: </strong>These findings are important for determining how treatments can best fit the needs of under-resourced older adults with chronic pain.</p>","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"549-556"},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11633828/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142731825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Spinal cord stimulation in a patient with an implantable cardioverter defibrillator for managing chronic chest pain: a case report and literature review.","authors":"Porras Bueno Cristian Orlando, Rangel Jaimes German William, Camargo Cárdenas Anamaria, Cediel Carrillo Ximena, Berdugo Pereira Eliana Milena","doi":"10.1080/17581869.2024.2426971","DOIUrl":"10.1080/17581869.2024.2426971","url":null,"abstract":"<p><p>The simultaneous use of spinal cord stimulation (SCS) and an implantable cardioverter-defibrillator (ICD) is safe and effective in selected patients with refractory chest pain. Our case highlights successful pain management with SCS without compromising ICD function. Careful patient selection, low device settings, and ongoing monitoring are crucial for achieving optimal outcomes.</p>","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"535-540"},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11622739/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142625989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain managementPub Date : 2024-10-01Epub Date: 2024-11-24DOI: 10.1080/17581869.2024.2432281
Giovanni E Ferreira, Hanan McLachlan, Andrew J McLachlan
{"title":"Antidepressants for pain in adults.","authors":"Giovanni E Ferreira, Hanan McLachlan, Andrew J McLachlan","doi":"10.1080/17581869.2024.2432281","DOIUrl":"10.1080/17581869.2024.2432281","url":null,"abstract":"","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"531-533"},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11622793/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142710891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain managementPub Date : 2024-10-01Epub Date: 2024-11-26DOI: 10.1080/17581869.2024.2433931
Brandon Goodwin, Jessica Mitchell, Erin Major, Alicia Podwojniak, Hanna Brancaccio, Katarina Rusinak, Matthew King, Hassan Tahir
{"title":"The efficacy of topical 8% capsaicin patches for the treatment of postsurgical neuropathic pain: a systematic review.","authors":"Brandon Goodwin, Jessica Mitchell, Erin Major, Alicia Podwojniak, Hanna Brancaccio, Katarina Rusinak, Matthew King, Hassan Tahir","doi":"10.1080/17581869.2024.2433931","DOIUrl":"10.1080/17581869.2024.2433931","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the benefits of topical 8% capsaicin patches for the decrease of postsurgical neuropathic pain level and area.</p><p><strong>Methods: </strong>A systematic review with pooled analysis was conducted utilizing the PRISMA 2020 guidelines. Five commonly used databases were employed utilizing a search string made from MeSH terms and boolean operators. Retrieved articles were then subjected to title and abstract appraisal, followed by full-text appraisal by two independent reviewers and an adjudicator to break ties.</p><p><strong>Results: </strong>A total of 127 articles were retrieved from five commonly used databases. Of the 127 articles, 20 were subjected to full-text appraisal, with 12 remaining for inclusion. Due to a heterogeneity greater than the 50% threshold provided by Cochrane, a random-effects pooled-analysis was conducted in lieu of meta-analysis. The random-effects pooled-analysis denotes an overall Cohen's d of 1.09 (95% CI: 0.58-1.56; <i>p</i> < 0.001). All studies that investigated neuropathic pain area denote a decrease in pain size, with some denoting a continued reduction with subsequent application.</p><p><strong>Conclusion: </strong>Further larger randomized-controlled trials are required to strengthen the position of topical capsaicin patches in the physician's armamentarium.</p><p><strong>Protocol registration: </strong>www.crd.york.ac.uk/prospero identifier is CRD42024542508.</p>","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"591-598"},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11622774/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142716817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain managementPub Date : 2024-10-01Epub Date: 2024-11-17DOI: 10.1080/17581869.2024.2430162
Inês Mendes-Andrade, Robert Pagan-Rosado, Nuno Ferreira-Silva, Mark Friedrich Hurdle
{"title":"A novel approach to refractory coccydynia: ultrasound- fluoroscopy-guided cryoablation of sacrococcygeal nerve.","authors":"Inês Mendes-Andrade, Robert Pagan-Rosado, Nuno Ferreira-Silva, Mark Friedrich Hurdle","doi":"10.1080/17581869.2024.2430162","DOIUrl":"10.1080/17581869.2024.2430162","url":null,"abstract":"<p><p>Coccydynia, also termed chronic pain in the tailbone, is a complex condition with limited treatment options for refractory cases. This case series introduces a novel approach for treating refractory coccydynia using cryoablation of the sacrococcygeal nerves under combined ultrasound and fluoroscopy guidance. Two female patients, suffering from chronic pain for over six months and unresponsive to conservative interventions, underwent cryoablation. Both patients reported significant pain relief, with more than 50% reduction in their numeric rating scale scores, and no major complications were observed during or after the procedure. Furthermore, we propose a clinical treatment algorithm to assist in selecting appropriate interventions for refractory coccydynia, based on the anatomical source of the pain. The findings suggest that cryoablation may be a valuable option for patients with persistent coccygeal pain; however, larger prospective studies are required to confirm its efficacy and long-term safety.</p>","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"541-547"},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11622740/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142649032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain managementPub Date : 2024-10-01Epub Date: 2024-11-22DOI: 10.1080/17581869.2024.2421153
María B Sánchez, Michael J Callaghan, James Selfe, Michael Twigg, Toby Smith
{"title":"Efficacy of transdermal anti-inflammatory patches for musculoskeletal pain: a systematic review and meta-analysis.","authors":"María B Sánchez, Michael J Callaghan, James Selfe, Michael Twigg, Toby Smith","doi":"10.1080/17581869.2024.2421153","DOIUrl":"10.1080/17581869.2024.2421153","url":null,"abstract":"<p><p><b>Aim:</b> To determine the efficacy of transdermal anti-inflammatory patches in the treatment of acute and chronic musculoskeletal pain.<b>Methods:</b> A comprehensive search of: Cochrane Central register of controlled trials, EMBASE, MEDLINE, CINAHL and PubMed, for studies using transdermal anti-inflammatory patches vs placebo for management of musculoskeletal pain, e.g. soft tissue injuries or tendonitis (last search January 2024). Cochrane Risk of Bias Tools v1 was used for quality assessment and GRADE determined certainty of evidence. Meta-analysis was performed.<b>Results:</b> Twenty-three randomized placebo-controlled trials (n = 4729) were included. There was low-certainty evidence that transdermal patches provided statistically and clinically significant pain relief on movement at long-term follow-up for chronic musculoskeletal pain (effect size -2-69 (95% CI: -4.14, -1.24) and at short-term follow-up which was non-clinically significant, (-1.24: 95% CI: -1.78, -0.69).<b>Conclusion:</b> Several types of transdermal anti-inflammatory patches may offer short-term and long-term pain relief for acute and chronic musculoskeletal conditions. However, the clinical significance of this effect for the long-term pain relief was based on low-certainty evidence of transdermal anti-inflammatory patches versus placebo; for short-term pain there was an overall non-clinically significant improvement. Performing a meta-analysis for all outcomes was not possible due to insufficiency in the evidence-base.<b>Protocol registration:</b> www.crd.york.ac.uk/prospero identifier is CRD42020185944.</p>","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"557-569"},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11730417/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142688410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain managementPub Date : 2024-09-01Epub Date: 2024-11-18DOI: 10.1080/17581869.2024.2427564
Georgios Karagiorgis, Savvas Christofilos, Christina Deligianni, Ioanna Spanou, Sofia Vassilopoulou, Dimos-Dimitrios D Mitsikostas
{"title":"Galcanezumab add-on in refractory cluster headache. A case series.","authors":"Georgios Karagiorgis, Savvas Christofilos, Christina Deligianni, Ioanna Spanou, Sofia Vassilopoulou, Dimos-Dimitrios D Mitsikostas","doi":"10.1080/17581869.2024.2427564","DOIUrl":"10.1080/17581869.2024.2427564","url":null,"abstract":"<p><p>Cluster headache (CH), a highly disabling condition, lacks disease-specific, mechanism-based prophylactic treatment. Galganezumab, a monoclonal antibody targeting the calcitonin gene-related peptide, reduced the weekly attacks of CH in one randomized, placebo-controlled trial for the prevention of episodic CH (eCH), but this effect was not detected in people with chronic CH (cCH). In this case series, we systematically monitored the efficacy and safety outcomes of adjunctive therapy in 11 people with refractory CH (failure of ≥ 3 prophylactic treatments; eCH <i>n</i> = 5, cCH, <i>n</i> = 6) who received galcanezumab (120-360 mg monthly) for 3 consecutive months. All participants received intermediate treatment with oral steroids or a great occipital nerve block ≥ 2 months before starting galcanezumab treatment. After galcanezumab treatment, the average number of weekly CH attacks and weekly days with any symptomatic treatment for CH decreased significantly from 16.0 ± 9.4 and 6.50 ± 3.59 before treatment to 1.8 ± 1.32 (<i>p</i> = 0.002) and 1.8 ± 3.36 (<i>p</i> = 0.001) at month 3 of treatment, respectively. Two participants with cCH showed no change in the number of attacks with galcanezumab. No serious adverse events were recorded. These data, along with those of previous real-world reports, suggest that galcanezumab may help people with refractory CH as an add-on treatment.</p>","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"491-495"},"PeriodicalIF":1.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11721606/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142668644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain managementPub Date : 2024-09-01Epub Date: 2024-10-28DOI: 10.1080/17581869.2024.2408114
Elizabeth A Stewart, Andrea S Lukes, Roberta Venturella, Juan-Camilo Arjona Ferreira, Yulan Li, Elke Hunsche, Rachel B Wagman, Ayman Al-Hendy
{"title":"A plain language summary describing changes in pain associated with uterine fibroids among women receiving relugolix combination therapy.","authors":"Elizabeth A Stewart, Andrea S Lukes, Roberta Venturella, Juan-Camilo Arjona Ferreira, Yulan Li, Elke Hunsche, Rachel B Wagman, Ayman Al-Hendy","doi":"10.1080/17581869.2024.2408114","DOIUrl":"10.1080/17581869.2024.2408114","url":null,"abstract":"<p><strong>What is this summary about?: </strong>This is a summary of two research studies (known as clinical trials) called LIBERTY 1 and LIBERTY 2. These studies compared how well a medicine called relugolix combination therapy and placebo worked in reducing heavy menstrual bleeding (periods) in women with uterine fibroids (published in a separate article referenced in the section: Where can readers find more information on these studies?). Researchers also looked at whether women with moderate to severe pain from uterine fibroids saw improvement in their worst pain symptoms after 24 weeks of treatment (results described in the present summary).</p><p><strong>What are the key takeaways?: </strong>Women with moderate to severe pain from uterine fibroids (menstrual or nonmenstrual pain) took either relugolix combination therapy or placebo (once daily by mouth) for 24 weeks. During the last 5 weeks of treatment, 65% of women taking relugolix combination therapy and 19% of women taking placebo reported having minimal or no menstrual pain. Similarly, 45% of women taking relugolix combination therapy and 22% of women taking placebo reported having minimal or no non-menstrual pain. During the same time period, 71% of the women taking relugolix combination therapy and 40% of women taking placebo reported their worst pain was reduced by about one third compared with the start of the study.</p><p><strong>What were the main conclusions reported by the researchers?: </strong>Women with moderate to severe pain from uterine fibroids taking relugolix combination therapy were more likely to have minimal or no pain from uterine fibroids after treatment compared with women taking placebo.<b>Clinical Trial Registration:</b> NCT03049735 (LIBERTY 1), NCT03103087 (LIBERTY 2) (ClinicalTrials.gov).</p>","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"469-476"},"PeriodicalIF":1.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11728327/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142505799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain managementPub Date : 2024-09-01Epub Date: 2024-10-04DOI: 10.1080/17581869.2024.2407283
Soun Sheen, Kent Nouri
{"title":"Sustained relief with spinal cord stimulator despite anterior lead migration: a case report.","authors":"Soun Sheen, Kent Nouri","doi":"10.1080/17581869.2024.2407283","DOIUrl":"10.1080/17581869.2024.2407283","url":null,"abstract":"<p><p>Lead migration is a common complication of spinal cord stimulation, although anterior migration is rare. While early studies suggested that anterior stimulation may produce analgesic effects, it is thought to be poorly tolerated due to abnormal paresthesia and muscle contractions due to its proximity to the corticospinal tract. This case report presents a unique case of sustained pain relief despite anterior lead migration, which suggests that anterior column stimulation may hold clinical significance for pain management. Further studies are needed to explore its analgesic mechanisms and potential therapeutic application. Strategies to prevent lead migration, particularly in the early postoperative period, are also crucial for optimizing outcomes.</p>","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"487-490"},"PeriodicalIF":1.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11721612/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142372521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain managementPub Date : 2024-09-01Epub Date: 2024-10-22DOI: 10.1080/17581869.2024.2411930
Bhuvan Kc, Alian A Alrasheedy, Mohamed Izham Mohamed Ibrahim, Vibhu Paudyal, Christina Malini Christopher, Sunil Shrestha, Shakti Shrestha
{"title":"Combatting opioid misuse, overuse and abuse: a systematic review of pharmacists' services and outcomes.","authors":"Bhuvan Kc, Alian A Alrasheedy, Mohamed Izham Mohamed Ibrahim, Vibhu Paudyal, Christina Malini Christopher, Sunil Shrestha, Shakti Shrestha","doi":"10.1080/17581869.2024.2411930","DOIUrl":"10.1080/17581869.2024.2411930","url":null,"abstract":"<p><p><b>Aim:</b> To examine the range of services pharmacists provide and their impact on patient outcomes, harm reduction, and appropriate opioid use.<b>Methods:</b> Six databases were searched (MEDLINE, EMBASE, Scopus, PsycINFO, CENTRAL and Cochrane Methodology Register) from inception to March 2023. The protocol was registered in PROSPERO (CRD42023401895).<b>Results:</b> Twenty-nine studies identified five key areas of pharmacist interventions in opioid management-naloxone programs and opioid de-escalation, patient and primary healthcare providers' education and motivational interview, prescription monitoring and opioid risk screening, clinical pharmacy interventions (pharmacotherapy, medication review, prescribing, adherence monitoring), and collaborative healthcare approaches to promote optimal opioid use. Outcomes assessment indicated harm reduction, improved safety, increased non-opioid analgesic use, decreased opioid consumption, and enhanced pain management.<b>Conclusion:</b> This review underscores pharmacists' vital role in tackling opioid misuse, overuse and abuse, providing a foundation for evidence-based policies to minimize harm and promote optimal opioid use.</p>","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"519-529"},"PeriodicalIF":1.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11728331/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142505800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}