Pain management最新文献_第3页

Symptomatic injection granuloma of buttock and management with ultrasound-guided barbotage procedure. 臀部症状性注射性肉芽肿及超声引导下的穿刺治疗。

IF 1.7

Pain management Pub Date : 2026-10-01 Epub Date: 2026-06-16 DOI: 10.1080/17581869.2026.2688378

Burak Tayyip Dede, Muhammed Oğuz, Bülent Alyanak, Fatih Bağcier

{"title":"Symptomatic injection granuloma of buttock and management with ultrasound-guided barbotage procedure.","authors":"Burak Tayyip Dede, Muhammed Oğuz, Bülent Alyanak, Fatih Bağcier","doi":"10.1080/17581869.2026.2688378","DOIUrl":"10.1080/17581869.2026.2688378","url":null,"abstract":"Injection granulomas (IGs) are recognized as a consequence of the injection of injectates into adipose tissue after routine drug or vaccine injections without reaching the muscular tissue. A series of reactions of the injectates in adipose tissue results in necrotic tissue and deposition of calcium crystals. IGs are usually asymptomatic but may rarely be symptomatic. In the past, symptomatic cases were mostly managed conservatively or surgically. However, to the best of our knowledge, no procedure other than surgical or conservative treatment has been reported. A 57-year-old patient with a history of multiple intramuscular diclofenac injections presented with localized right buttock pain for 8 months. The patient, who did not respond to conservative treatment, underwent an ultrasound-guided barbotage procedure commonly used in the diagnosis of calcific periarthritis. The patient's pain complaint was evaluated according to the visual analog scale (VAS). The patient reported VAS:7 before the barbotage procedure and VAS:2 at the sixth week follow-up after the barbotage procedure. This case report, provided that it is supported by future studies, suggests that the ultrasound-guided barbotage procedure, which is commonly used in patients with calcific periarthritis, may be a promising treatment method in IG cases unresponsive to conservative treatment.","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"1093-1097"},"PeriodicalIF":1.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13641573/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148259211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prehospital analgesia in adults using inhaled methoxyflurane: a feasibility study. 成人吸入甲氧基氟醚院前镇痛的可行性研究

IF 1.7

Pain management Pub Date : 2026-10-01 DOI: 10.1080/17581869.2026.2736033

Michael A Austin, Julie Sinclair, Jane Marchand, Michael Slatter, Cory E Goldstein, Ben De Mendonca, Monica Taljaard, Christian Vaillancourt

{"title":"Prehospital analgesia in adults using inhaled methoxyflurane: a feasibility study.","authors":"Michael A Austin, Julie Sinclair, Jane Marchand, Michael Slatter, Cory E Goldstein, Ben De Mendonca, Monica Taljaard, Christian Vaillancourt","doi":"10.1080/17581869.2026.2736033","DOIUrl":"https://doi.org/10.1080/17581869.2026.2736033","url":null,"abstract":"Background: Acute pain is common and often undertreated prehospitally. Inhaled low-dose methoxyflurane is a rapid, patient-controlled analgesic with internationally reported safety data but has not been studied for prehospital use in Canada; this feasibility study informs a future multicentre stepped-wedge cluster randomized trial.Methods: We conducted a single-center prospective observational study in a Canadian paramedic service to assess feasibility for a stepped-wedge cluster randomized trial. Adult trauma patients (≥18-years) with Glasgow Coma Scale(GCS) ≥14 and numeric rating scale(NRS) pain ≥4 received self-administered inhaled methoxyflurane (3mls). Feasibility outcomes included regulatory timelines, protocol adherence, and data completeness; secondary outcomes included pain documentation and adverse events.Results: Ethics board approval was obtained in 93 days, slightly exceeding the target, while trial readiness occurred 404 days post-approval and did not meet feasibility targets. Protocol compliance was high (95%) (92/97), and post-treatment pain scores were documented in 90% (83/92) of cases. Median pain decreased from 8/10 pre-treatment to 5/10 post-treatment. Side effects occurred in 23% of patients, were mostly mild, and no serious methoxyflurane-related adverse events were observed.Conclusions: The results of this feasibility study were used to inform the deployment of an ongoing prospective stepped-wedge open-label, cluster randomized trial to inform clinical care in the real world.Clinical trial registration: www.clinicaltrials.gov identifier is NCT04287803.","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"1-10"},"PeriodicalIF":1.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149113535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of whole spine electrotherapy in individuals with chronic low back pain: a retrospective controlled study. 慢性腰痛患者全脊柱电疗的有效性：一项回顾性对照研究。

IF 1.7

Pain management Pub Date : 2026-10-01 Epub Date: 2026-07-31 DOI: 10.1080/17581869.2026.2710353

Muzeyyen Oz, Yasemin Ozel Asliyuce, Aybuke Fanuscu, Ozlem Ulger

{"title":"Effectiveness of whole spine electrotherapy in individuals with chronic low back pain: a retrospective controlled study.","authors":"Muzeyyen Oz, Yasemin Ozel Asliyuce, Aybuke Fanuscu, Ozlem Ulger","doi":"10.1080/17581869.2026.2710353","DOIUrl":"10.1080/17581869.2026.2710353","url":null,"abstract":"Introduction: Chronic low back pain (cLBP) significantly impacts functional capacity and psychological well-being. This study investigated the efficacy of a whole-spine electrical stimulation system (StimaWELL 120MTRS) as a multimodal intervention to reduce pain and disability in this population.Areas covered: A controlled trial was conducted with sixty-one participants, assigned to either a treatment group (n = 30) or a waitlist-control group (n = 31). The intervention consisted of 30-minute whole-spine electrical stimulation sessions twice weekly for four weeks. Evaluation parameters included the Numeric Pain Scale (NPS) for pain intensity, the Pain Catastrophizing Scale (PCS), the Oswestry Disability Index (ODI) for disability, and the Nottingham Health Profile (NHP) for quality of life (QoL). Analysis focused on both within-group improvements and between-group comparisons to determine the system's clinical impact.Expert opinion/commentary: The findings demonstrate that whole-spine electrotherapy was associated with improvements in pain at rest and at night, reduced catastrophizing, and enhanced overall QoL compared to no intervention. This technology may offer a noninvasive approach for the comprehensive management of cLBP by addressing both physical symptoms and psychological factors like catastrophizing.","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"1131-1140"},"PeriodicalIF":1.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13641464/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148631317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Does gabapentin add value to multimodal analgesia in thoracic surgery? A procedure-specific meta-analysis. 加巴喷丁在胸外科多模式镇痛中有价值吗？特定手术的荟萃分析。

IF 1.7

Pain management Pub Date : 2026-10-01 Epub Date: 2026-06-29 DOI: 10.1080/17581869.2026.2694372

Gabriel Lemos González, Vitor Alves Felippe, Bruno Francisco Minetto Wegner, Gustavo Roberto Minetto Wegner, Iaci Luisa Lopes de Mattos, Tatiana Souza do Nascimento, Lucas Arêa Leão Barreto, Carlos Darcy Alves Bersot, Fani Nhuch, Marcos Adriano Lessa

{"title":"Does gabapentin add value to multimodal analgesia in thoracic surgery? A procedure-specific meta-analysis.","authors":"Gabriel Lemos González, Vitor Alves Felippe, Bruno Francisco Minetto Wegner, Gustavo Roberto Minetto Wegner, Iaci Luisa Lopes de Mattos, Tatiana Souza do Nascimento, Lucas Arêa Leão Barreto, Carlos Darcy Alves Bersot, Fani Nhuch, Marcos Adriano Lessa","doi":"10.1080/17581869.2026.2694372","DOIUrl":"10.1080/17581869.2026.2694372","url":null,"abstract":"Aims: Thoracic surgery is associated with severe acute and chronic pain, high opioid use, and other adverse outcomes. Gabapentin is commonly used perioperatively, but its effectiveness remains uncertain. This systematic review and meta-analysis evaluated the efficacy and safety of perioperative gabapentin versus placebo after thoracic surgery.Patients and methods: Cochrane, Embase, PubMed, and Web of Science were searched through 29 August 2025 for randomized controlled trials comparing gabapentin with placebo in adults undergoing thoracic surgery. The primary outcome was pain at 24 hours. Secondary outcomes included pain at other time points, opioid consumption, chronic pain, and adverse events. Data were pooled using random-effects models.Results and conclusions: Six trials including 748 patients were analyzed. Gabapentin had no significant effect on rest pain at 24 hours (MD -0.13; 95% CI -1.17 to 0.91). A non-significant trend toward worse cough-evoked pain at 24 hours was observed with gabapentin (MD 0.53; 95% CI 0.00 to 1.07). Gabapentin also did not significantly affect opioid consumption, pain chronification, or adverse events such as nausea, sedation, or delirium. Based on low-certainty evidence, perioperative gabapentin does not appear to provide meaningful benefit after thoracic surgery.Protocol registration: The www.crd.york.ac.uk/prospero identifier is CRD420251136259.","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"1161-1169"},"PeriodicalIF":1.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13641435/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148346026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical care pathways for individuals with comorbid mental health disorders presenting to emergency with acute musculoskeletal pain: a narrative review. 临床护理途径的个人共病精神健康障碍呈现紧急急性肌肉骨骼疼痛：叙述性回顾。

IF 1.7

Pain management Pub Date : 2026-10-01 Epub Date: 2026-06-15 DOI: 10.1080/17581869.2026.2688374

Priya Arora, James Elliott, Fereshteh Pourkazemi

{"title":"Clinical care pathways for individuals with comorbid mental health disorders presenting to emergency with acute musculoskeletal pain: a narrative review.","authors":"Priya Arora, James Elliott, Fereshteh Pourkazemi","doi":"10.1080/17581869.2026.2688374","DOIUrl":"10.1080/17581869.2026.2688374","url":null,"abstract":"Acute musculoskeletal (MSK) pain remains a leading contributor to global disability, with little reduction in its burden over the past three decades. Despite increasing recognition of the prognostic role of psychological comorbidities such as anxiety, depression, and stress, clinical care for MSK pain continues to prioritize biomedical interventions, often at the expense of psychosocial considerations. This disconnect is particularly evident in emergency department (ED) settings, where care pathways focus on immediate physical assessment and discharge planning, with limited integration of mental health screening or support. Individuals presenting with acute MSK pain and comorbid mental health conditions may therefore experience fragmented care, increasing their risk of chronicity and suboptimal outcomes. This narrative review synthesizes current evidence on clinical care pathways for individuals presenting to EDs with acute MSK pain in the context of preexisting mental health disorders. It highlights the limitations of existing models of care, underscores the need for integrated biopsychosocial approaches, and identifies opportunities for improving patient-centered outcomes through more holistic and prognostically informed care strategies.","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"1197-1204"},"PeriodicalIF":1.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13641519/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148252805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Innovative integration of high dose ketamine infusion, psychological services, and specialized multidisciplinary pain care for refractory pain syndromes. 创新整合高剂量氯胺酮输注，心理服务，和专门的多学科疼痛护理难治性疼痛综合征。

IF 1.7

Pain management Pub Date : 2026-10-01 Epub Date: 2026-07-15 DOI: 10.1080/17581869.2026.2696883

K Curtis, A Muere, E Robertson, V Bains, D Alvares, A Kalleitner, P Peng, P Tumber, E Baig, Y Hoydonckx, P Kumar, S Sahni, A Alomari, T Di Renna, K Ladha, A Bhatia, N Soneji

{"title":"Innovative integration of high dose ketamine infusion, psychological services, and specialized multidisciplinary pain care for refractory pain syndromes.","authors":"K Curtis, A Muere, E Robertson, V Bains, D Alvares, A Kalleitner, P Peng, P Tumber, E Baig, Y Hoydonckx, P Kumar, S Sahni, A Alomari, T Di Renna, K Ladha, A Bhatia, N Soneji","doi":"10.1080/17581869.2026.2696883","DOIUrl":"10.1080/17581869.2026.2696883","url":null,"abstract":"Ketamine is a noncompetitive antagonist of the N-methyl-D-aspartate receptor that has garnered significant interest as a treatment for both chronic pain and mental health symptoms in the last two decades. The authors introduce the methodological framework of the Ketamine Infusion Pain Program (KIPP) at Toronto Western Hospital (TWH) and outline a high dose ketamine infusion (HDKI) regimen for refractory pain syndromes implemented through an innovative multidisciplinary care model. HDKIs have been offered at TWH since 2010 and in 2023, the KIPP was formally established and reconceptualized to include multidisciplinary services. The redesign included peri-ketamine psychology services to provide education, support, and post-ketamine integration, and to optimize adaptive behaviors in the post-ketamine period. At KIPP, ketamine (0.5 mg.kg-1) is provided intravenously as a bolus, followed by an infusion dose up to 1 mg-1.kg.hr-1 IV for six hours. The KIPP is collecting data on pain, psychological factors, sleep, and functioning pre- and post-HDKI to evaluate patient outcomes, which will be presented in a future article. Future directions include further refinement of dosing protocols and co-administration of other medications and the expansion of peri-infusion psychology services with increased focus on preparation and integration, as well as the evaluation of these initiatives.","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"1099-1112"},"PeriodicalIF":1.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13641621/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148448640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Virtual reality in musculoskeletal pain management. 虚拟现实在肌肉骨骼疼痛管理中的应用。

IF 1.7

Pain management Pub Date : 2026-09-29 DOI: 10.1080/17581869.2026.2739418

J Bart Staal, Syl Slatman, Beate Dejaco, Niki Stolwijk, Harry van Goor, Jesper Knoop

{"title":"Virtual reality in musculoskeletal pain management.","authors":"J Bart Staal, Syl Slatman, Beate Dejaco, Niki Stolwijk, Harry van Goor, Jesper Knoop","doi":"10.1080/17581869.2026.2739418","DOIUrl":"https://doi.org/10.1080/17581869.2026.2739418","url":null,"abstract":"Over the past years, virtual reality has emerged as an increasingly popular treatment option for both acute and chronic musculoskeletal pain. This special report explores what virtual reality entails, its potential working mechanisms, and the current state of evidence, before outlining directions for future research. The defining feature of virtual reality is its ability to immerse users in a three-dimensional, computer-simulated environment, typically via a headset, where they can interact using body movements and handheld controllers or other devices. For musculoskeletal pain, virtual reality's potential working mechanisms include pain distraction, fear reduction and relaxation, and the opportunity to engage in physical activities in an appealing and motivating way. To date, meta-analyses suggest that virtual reality may be effective in reducing fear and pain post-intervention. To strengthen the evidence base, future randomized trials should be preceded by carefully designed preparatory studies, guided by the VR-CORE framework. These efforts should include investigations into the assumed mechanisms of virtual reality. Researchers are also encouraged to conduct well-designed placebo-controlled trials in this field and to adhere to existing reporting guidelines to enhance transparency, reproducibility, and the overall quality of virtual reality studies.","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"1-6"},"PeriodicalIF":1.7,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149075685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mentalizing & InteRpersonal Recognition of Others' Relational States (MIRROR): a patient-directed intervention for navigating clinical encounters in chronic pain. 对他人关系状态的心理化和人际认知（MIRROR）：一种以患者为导向的干预，用于引导慢性疼痛的临床遭遇。

IF 1.7

Pain management Pub Date : 2026-09-28 DOI: 10.1080/17581869.2026.2740677

Jolin B Yamin, Arvina Grahl, Alessandra Anzolin, Thi Dieu Ni Doan, Seneca Ellis, Lara Gardiner, Isabella Hewardt, Soo Ahn Lee, Jeungchan Lee, John M Kelley, Ted Kaptchuk, Vitaly Napadow, Robert R Edwards

{"title":"Mentalizing & InteRpersonal Recognition of Others' Relational States (MIRROR): a patient-directed intervention for navigating clinical encounters in chronic pain.","authors":"Jolin B Yamin, Arvina Grahl, Alessandra Anzolin, Thi Dieu Ni Doan, Seneca Ellis, Lara Gardiner, Isabella Hewardt, Soo Ahn Lee, Jeungchan Lee, John M Kelley, Ted Kaptchuk, Vitaly Napadow, Robert R Edwards","doi":"10.1080/17581869.2026.2740677","DOIUrl":"https://doi.org/10.1080/17581869.2026.2740677","url":null,"abstract":"Introduction: Chronic pain can lead to challenges in social functioning that extend into healthcare. The Mentalizing & InteRpersonal Recognition of Others' Relational States (MIRROR) intervention was developed to support patients' relational and communication skills in healthcare by targeting mentalizing (the ability to understand mental states of oneself and others). This paper describes MIRROR and reports preliminary findings regarding feasibility and acceptability across two pain samples.Methods: Eleven patients with chronic low back pain (cLBP, mean age 39.64 ± 16.37) and 12 patients with fibromyalgia (FM, mean age 38.83 ± 15.25) completed the four-session intervention. Questionnaires assessed session value and applicability, perceived benefit and generalization, and Perceived Efficacy in Patient-Physician Interactions (PEPPI).Results: Session ratings reflected moderate-to-high value and applicability (mean over 4 sessions: cLBP 1.22 ± 0.46, FM 1.45 ± 0.46; scale: -2 to 2), and perceived benefit and generalization (mean cLBP 0.88 ± 0.77, FM 0.71 ± 0.58; scale: -2 to 2). Exploratory pre-post changes in PEPPI scores indicated a medium effect observed in cLBP (Hedges' g = 0.52) and a small effect in FM (Hedges' g = 0.10). Open-ended feedback supported acceptability and feasibility.Conclusions: MIRROR appears feasible and acceptable as an intervention engaging mentalizing methods for enhancing patients' ability to navigate clinical interactions. Further research should evaluate whether engaging mentalizing abilities improves subsequent healthcare communication and outcomes.Clinical trial registration: www.clinicaltrials.gov identifier is NCT06157866.","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"1-14"},"PeriodicalIF":1.7,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149070040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Does output voltage influence the clinical effects of pulsed radiofrequency of the suprascapular and axillary nerves in chronic shoulder pain? A double-masked, non-randomized comparative study. 输出电压是否影响肩胛上神经和腋窝神经脉冲射频治疗慢性肩痛的临床效果？一项双盲、非随机对照研究。

IF 1.7

Pain management Pub Date : 2026-09-28 DOI: 10.1080/17581869.2026.2741365

Juan Marcos Asensio-Samper, José De Andrés, Vicente Monsalve-Dolz, Gustavo Fabregat-Cid

{"title":"Does output voltage influence the clinical effects of pulsed radiofrequency of the suprascapular and axillary nerves in chronic shoulder pain? A double-masked, non-randomized comparative study.","authors":"Juan Marcos Asensio-Samper, José De Andrés, Vicente Monsalve-Dolz, Gustavo Fabregat-Cid","doi":"10.1080/17581869.2026.2741365","DOIUrl":"https://doi.org/10.1080/17581869.2026.2741365","url":null,"abstract":"Aims: Chronic shoulder pain can cause substantial disability. This study evaluated whether increasing pulsed radiofrequency (PRF) output voltage from 45 V to 85 V provides additional benefit when treating the suprascapular and axillary nerves.Patients and methods: In this prospective, double-masked, non-randomized comparative study, 80 patients (40 per group) with refractory chronic shoulder pain underwent ultrasound-guided PRF at 45 V or 85 V using otherwise identical parameters. The primary outcome was pain intensity (visual analog scale [VAS]); secondary outcomes included QuickDASH, SF-12, HADS, patient global improvement, analgesic use, and safety. Outcomes were assessed over 6 months using a repeated-measures general linear model.Results: At 6 months, estimated marginal mean VAS scores were 5.89 (95% CI 5.18-6.59) with 45 V and 5.47 (95% CI 4.92-6.02) with 85 V. Neither the group effect (p = 0.137) nor group-by-time interaction (p = 0.815) was significant. QuickDASH scores were 53.84 (95% CI 48.02-59.66) and 49.86 (95% CI 44.30-55.42), respectively, with a significant group-by-time interaction (p = 0.018).Conclusions: Increasing PRF voltage from 45 V to 85 V was not associated with a significant difference in pain trajectories, although small differences in secondary outcomes cannot be excluded.","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"1-8"},"PeriodicalIF":1.7,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149070034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Airplane headache: a scoping review of mechanisms and reported therapeutic strategies. 飞机头痛：一个范围审查机制和报道的治疗策略。

IF 1.7

Pain management Pub Date : 2026-09-23 DOI: 10.1080/17581869.2026.2736043

Haqi Abdelkarim Omar, Dilara Onan, Marta Waliszewska-Prosół, Lanfranco Pellesi

{"title":"Airplane headache: a scoping review of mechanisms and reported therapeutic strategies.","authors":"Haqi Abdelkarim Omar, Dilara Onan, Marta Waliszewska-Prosół, Lanfranco Pellesi","doi":"10.1080/17581869.2026.2736043","DOIUrl":"https://doi.org/10.1080/17581869.2026.2736043","url":null,"abstract":"Introduction: Airplane headache (AH) is a headache disorder recognized in the International Classification of Headache Disorders, 3rd edition (ICHD-3) and characterized by severe, short-lasting, fronto-orbital pain occurring during aircraft take-off or, more typically, landing. Despite growing clinical recognition, evidence regarding its epidemiology, pathophysiology and management remains fragmented across heterogeneous studies.Areas covered: This scoping review maps the current literature on AH based on structured searches in PubMed and Embase from inception to 30 April 2026. Thirty-three studies were included, collectively involving several hundred patients, predominantly case reports and small case series, with a small number of cross-sectional surveys and a single experimental study using a hypobaric chamber model. Findings were organized thematically.Expert opinion: AH is best conceptualized as a disorder where a stereotyped barometric stimulus triggers a predisposed trigeminovascular system, although this interpretation remains speculative. Whether current diagnostic criteria are overly restrictive remains an open question and warrants formal validation. Therapeutic strategies, meanwhile, rely entirely on uncontrolled data. Randomized cross-over trials and mechanistic interpretation studies represent the most pressing priorities for future research.","PeriodicalId":20000,"journal":{"name":"Pain management","volume":" ","pages":"1-10"},"PeriodicalIF":1.7,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149030965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0