Parkinsonism & related disorders最新文献_第4页

A framework for multidisciplinary management of autonomic dysfunction in Parkinson disease. 帕金森病自主神经功能障碍的多学科管理框架。

IF 4.3 3区医学

Parkinsonism & related disorders Pub Date : 2026-07-29 DOI: 10.1016/j.parkreldis.2026.108905

Cameron Miller-Patterson, Delaram Safarpour, Katherine Longardner, Guillaume Lamotte, Abhishek Lenka, Abhimanyu Mahajan, Sarah Diamond, Ankita Gupta, Julie Hershberg, Sahib Khalsa, Brian Olshansky, Gregory M Pontone, Robert Rope, Ronald F Pfeiffer, Indu Subramanian

{"title":"A framework for multidisciplinary management of autonomic dysfunction in Parkinson disease.","authors":"Cameron Miller-Patterson, Delaram Safarpour, Katherine Longardner, Guillaume Lamotte, Abhishek Lenka, Abhimanyu Mahajan, Sarah Diamond, Ankita Gupta, Julie Hershberg, Sahib Khalsa, Brian Olshansky, Gregory M Pontone, Robert Rope, Ronald F Pfeiffer, Indu Subramanian","doi":"10.1016/j.parkreldis.2026.108905","DOIUrl":"https://doi.org/10.1016/j.parkreldis.2026.108905","url":null,"abstract":"Autonomic dysfunction (AD) is present in nearly all people with Parkinson disease (PD), contributing to tremendous morbidity and mortality. Highly variable presentations including cardiovascular, gastrointestinal, urogenital, and thermoregulatory dysfunction can substantially affect daily function, safety, medication tolerance, and quality of life. Although autonomic symptoms are frequently encountered in neurologic practice, their management frequently extends beyond the traditional scope of neurologic care and may require input from multiple disciplines. Despite the increasing complexity of PD care and the need for coordinated multidisciplinary involvement, there are currently limited practical frameworks to guide specialist collaboration. Consequently, people with PD and their caregivers are often left to navigate fragmented care systems, conflicting recommendations, and uncertainty regarding which clinician should guide management. To help address these gaps, we provide a framework for the possible indications for specialist referrals and the potential roles of different healthcare practitioners in evaluating and treating AD. The manuscript also discusses the intersection between autonomic and neuropsychiatric manifestations in PD and offers practical clinical guidance for addressing this overlap. By providing a framework informed by coauthors in movement disorders, autonomic disorders, cardiology, nephrology, gastroenterology, urogynecology, physical therapy, and psychiatry, we hope to encourage neurologists - who often serve as the central point of contact - to collaborate closely and actively engage multidisciplinary team members in the management of these complex patients.","PeriodicalId":19970,"journal":{"name":"Parkinsonism & related disorders","volume":" ","pages":"108905"},"PeriodicalIF":4.3,"publicationDate":"2026-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148689660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparing the two-axis classifications of hyperkinetic disorders. 多动障碍的两轴分类比较。

IF 4.3 3区医学

Parkinsonism & related disorders Pub Date : 2026-07-29 DOI: 10.1016/j.parkreldis.2026.108855

Alberto Albanese

{"title":"Comparing the two-axis classifications of hyperkinetic disorders.","authors":"Alberto Albanese","doi":"10.1016/j.parkreldis.2026.108855","DOIUrl":"https://doi.org/10.1016/j.parkreldis.2026.108855","url":null,"abstract":"This review analyzes the structure and content of the two-axis classification systems for hyperkinetic disorders. The first classification was developed for dystonia in 2013, a tremor classification appeared in 2018, and a myoclonus classification in 2025, together with a revision of the 2013 dystonia classification. In all these classifications, Axis I refers to clinical characteristics, and Axis II to etiology. However, for myoclonus there is also an Axis Ib dedicated to neurophysiology. The clinical features of dystonia are recognized by clinical assessment, whereas in the case of tremor, and particularly of myoclonus, neurophysiology plays a relevant role. In the tremor and myoclonus classifications, neurophysiology is included as an Axis I descriptor aside clinical assessment. The positioning of other laboratory tests differs among classifications. Neuroimaging is an etiological Axis II division in dystonia, whereas it is included aside other laboratory tests under Axis I in the tremor and myoclonus classifications. The results of genetic testing are included under Axis II in the dystonia and tremor classifications, instead under Axis I in the myoclonus classification. The positioning of functional movement disorders also differs, and for myoclonus a new Axis II etiology of \"functional neurological disorders\" has been added. These classification exercises highlight the specificity of different hyperkinetic disorders on the background of a comparable two-axis structure.","PeriodicalId":19970,"journal":{"name":"Parkinsonism & related disorders","volume":" ","pages":"108855"},"PeriodicalIF":4.3,"publicationDate":"2026-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148670447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

From larynx to limbs-neuronal ceroid lipofuscinoses presenting with a predominant dystonia phenotype in siblings. 从喉部到四肢-神经元类脂褐变在兄弟姐妹中表现为主要的肌张力障碍表型。

IF 4.3 3区医学

Parkinsonism & related disorders Pub Date : 2026-07-27 DOI: 10.1016/j.parkreldis.2026.108901

Ranjot Kaur, Ayush Agarwal, Achal K Srivastava, Divyani Garg

引用次数: 0

Management of non-motor symptoms in Parkinson's disease: Lessons through a cultural lens. 帕金森病非运动症状的处理：文化视角下的经验教训

IF 4.3 3区医学

Parkinsonism & related disorders Pub Date : 2026-07-24 DOI: 10.1016/j.parkreldis.2026.108439

Indu Subramanian, Pinky Agarwal, Michiko K Bruno

{"title":"Management of non-motor symptoms in Parkinson's disease: Lessons through a cultural lens.","authors":"Indu Subramanian, Pinky Agarwal, Michiko K Bruno","doi":"10.1016/j.parkreldis.2026.108439","DOIUrl":"https://doi.org/10.1016/j.parkreldis.2026.108439","url":null,"abstract":"Parkinson's disease (PD) affects individuals across diverse cultural, linguistic, and socioeconomic backgrounds worldwide. While non-motor symptoms (NMS) are among the most disabling features of PD, the influence of culture on their recognition, reporting, and management remains underexplored. This review examines cultural factors that shape the experience and care of NMS in PD, with particular attention to Asian populations, which have historically received limited focus in health disparities literature. Drawing on evidence from diverse global populations, we explore how cultural beliefs, stigma, family dynamics, spirituality, language, and trust in healthcare systems influence symptom interpretation, help-seeking behaviors, treatment engagement, caregiving, and end-of-life decision-making. Sensitive symptoms such as bladder, bowel and sexual dysfunction, as well as mental health symptoms may be underreported because of stigma, shame, or cultural norms. Immigrant populations may avoid \"bothering\" healthcare providers, while language barriers and mistrust can further impede communication and access to care. Cultural values also influence decision-making preferences. In contrast to Western models that prioritize individual autonomy, some patients prefer family-centered decision-making, with designated family members guiding healthcare choices. Concepts such as filial piety, \"familismo\", and culturally defined gender roles (superwoman schema and stoic masculinity) shape caregiving and acceptance of treatment recommendations. Culturally enabled care is essential to equitable and person-centered PD management and can improve communication, reduce disparities, foster trust, and enhance quality of life for people living with PD and their families. Further research is urgently needed to better understand how culture intersects with NMS management and to develop culturally enabled models of care.","PeriodicalId":19970,"journal":{"name":"Parkinsonism & related disorders","volume":" ","pages":"108439"},"PeriodicalIF":4.3,"publicationDate":"2026-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148631277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An honor of a lifetime. 这是一生的荣幸。

IF 4.3 3区医学

Parkinsonism & related disorders Pub Date : 2026-07-16 DOI: 10.1016/j.parkreldis.2026.108443

Hubert H Fernandez

引用次数: 0

Is functional neurosurgery offering new hope for patients with hyperkinetic disorders? A mini-review of the current data on the use of DBS in hyperkinetic movement disorders. 功能性神经外科为多动障碍患者带来了新希望吗？对DBS治疗多动性运动障碍的最新数据进行综述。

IF 4.3 3区医学

Parkinsonism & related disorders Pub Date : 2026-07-11 DOI: 10.1016/j.parkreldis.2026.108419

Emily Tharp, Raja Mehanna

引用次数: 0

Point of view: Task-specific movement disorders—time for a reappraisal? 观点：任务特异性运动障碍——重新评估的时间？

IF 4.3 3区医学

Parkinsonism & related disorders Pub Date : 2026-07-01 Epub Date: 2026-04-28 DOI: 10.1016/j.parkreldis.2026.108326

Steven J. Frucht

引用次数: 0

Segmental brainstem myoclonus in ADCK3-Related ataxia: A novel phenomenon? adck3相关共济失调的节段性脑干肌阵挛：一种新现象？

IF 4.3 3区医学

Parkinsonism & related disorders Pub Date : 2026-07-01 Epub Date: 2025-01-04 DOI: 10.1016/j.parkreldis.2025.107262

Vito Luigi Colona, Giacomo Garone, Francesco Nicita, Lorena Travaglini, Stefano Pro, Maria Camilla Rossi-Espagnet, Anna Piluso, Eleonora Bisozzi, Donatella Lettori, Enrico Bertini, Gessica Vasco

引用次数: 0

Four innovations to bridge the evidence–practice gap in Parkinson's disease allied health guidelines 四项创新弥合了帕金森病相关健康指南中证据与实践的差距。

IF 4.3 3区医学

Parkinsonism & related disorders Pub Date : 2026-07-01 Epub Date: 2026-05-05 DOI: 10.1016/j.parkreldis.2026.108340

Anneli Langbroek-Amersfoort, Philip van der Wees, Bastiaan R. Bloem, Marten Munneke, Masja M. van het Hoofd, Femke van der Voort, Ingrid HWM. Sturkenboom

引用次数: 0

“Expert Commentary on Segmental brainstem myoclonus in ADCK3-related ataxia” adck3相关共济失调的节段性脑干肌阵挛专家评论

IF 4.3 3区医学

Parkinsonism & related disorders Pub Date : 2026-07-01 Epub Date: 2026-05-07 DOI: 10.1016/j.parkreldis.2026.108353

Hélio A.G. Teive

引用次数: 0