Pediatric Pulmonology最新文献_第7页

Beneficial economic effect of a virtual model of care for cystic fibrosis. 囊性纤维化虚拟治疗模式的经济效益。

IF 2.7 3区医学

Pediatric Pulmonology Pub Date : 2024-10-16 DOI: 10.1002/ppul.27330

Paola Iacotucci, Vincenzo Carnovale, Dandi Qiao, Lorenza Ferrillo, Alessandro Sanduzzi Zamparelli, Daniela Savi

引用次数: 0

Challenges in using the ROX index as a predictor of failure in high flow nasal cannula in infants with respiratory failure. 使用 ROX 指数预测呼吸衰竭婴儿高流量鼻插管失败的挑战。

IF 2.7 3区医学

Pediatric Pulmonology Pub Date : 2024-10-14 DOI: 10.1002/ppul.27332

Milena S Nascimento, Robinder G Khemani, Christopher J L Newth

引用次数: 0

Features of children with critical asthma hospitalized in a pediatric intensive care unit: Results from the ICU-3A study. 在儿科重症监护病房住院的重症哮喘患儿的特征：ICU-3A 研究结果。

IF 2.7 3区医学

Pediatric Pulmonology Pub Date : 2024-10-14 DOI: 10.1002/ppul.27322

Claire Eusebe, Stéphane Dauger, Pierre-Louis Leger, Véronique Houdouin, Sylvain Renolleau, Flore Amat

{"title":"Features of children with critical asthma hospitalized in a pediatric intensive care unit: Results from the ICU-3A study.","authors":"Claire Eusebe, Stéphane Dauger, Pierre-Louis Leger, Véronique Houdouin, Sylvain Renolleau, Flore Amat","doi":"10.1002/ppul.27322","DOIUrl":"https://doi.org/10.1002/ppul.27322","url":null,"abstract":"Introduction: Despite improvements in long-term asthma treatment, an increasing number of children are being hospitalized in pediatric intensive care units (PICU) for asthma. The main objective of this study was to describe a recent cohort of children hospitalized in PICU for asthma to identify risk factors associated with a need for respiratory support, and multiple PICU stays.Methods: We conducted a retrospective cohort study in three PICUs in Paris (intensive care units 3A Study), using medical files of children hospitalized for asthma between February 2019 and October 2020. Need for respiratory support was defined by the need for high-flow nasal cannula or mechanical ventilation (MV) (either noninvasive [NIV] or invasive [IMV]).Results: During the study period, 252 stays corresponding to 234 patients were analyzed. MV was required in 17.5% of stays, for significantly younger patients (2.37 vs. 4.18 years, p = 0.002). On multivariate analysis, a higher risk of progression to a need for respiratory support was found for children requiring magnesium sulfate or oxygen therapy ≥6 L/mn before PICU admission (RR 4.48; CI95% [1.85-10.89]; p = 0.001, and RR 2.86; CI95% [1.13-7.22]; p = 0.03, respectively), and those with atelectasis detected on chest radiography (RR 3.38; CI95% [1.43-8.00]; p < 0.01). Multiple PICU stays were associated with greater social deprivation (RR for French Deprivation Index 1.25; CI95% [1.03-1.51]; p = 0.03).Conclusion: Children experiencing social deprivation are at greater risk of multiple PICU stays for severe asthma. After transfer to PICU, children with chest radiograph detected atelectasis on admission are at higher risk of needing respiratory support.","PeriodicalId":19932,"journal":{"name":"Pediatric Pulmonology","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142472190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Post-infectious bronchiolitis obliterans in children after the end of the COVID-19 pandemic. COVID-19 大流行结束后的儿童感染性闭塞性支气管炎。

IF 2.7 3区医学

Pediatric Pulmonology Pub Date : 2024-10-14 DOI: 10.1002/ppul.27319

Carlos Martín-de Vicente, Virginia Giménez-Molina, Rafael Fernández-Atuan, Laura Buzón-Serrano

引用次数: 0

Atypical presentation of primary lung abscess in an infant. 婴儿原发性肺脓肿的非典型表现。

IF 2.7 3区医学

Pediatric Pulmonology Pub Date : 2024-10-14 DOI: 10.1002/ppul.27324

Katherine Briski, Bethany Murphy, DeAnna Diaz, Andrew Parrott, Maya Ramagopal, Marissa Botwinick, Fahmida Islam

引用次数: 0

Outpatient clinical care for bronchopulmonary dysplasia: A survey of the BPD collaborative. 支气管肺发育不良的门诊临床护理：支气管肺发育不良协作组调查。

IF 2.7 3区医学

Pediatric Pulmonology Pub Date : 2024-10-11 DOI: 10.1002/ppul.27296

Paul E Moore, Lystra P Hayden, Natalie M Villafranco, Demet Toprak, Jessica L Rice, Lawrence M Rhein, Antonia P Popova, Robin L McKinney, Winston M Manimtim, Jonathan C Levin, Khanh V Lai, Susan C Gage, Manvi Bansal, Christopher D Baker, Eric D Austin, Amit Agarwal, Sharon A McGrath-Morrow, Joseph M Collaco

{"title":"Outpatient clinical care for bronchopulmonary dysplasia: A survey of the BPD collaborative.","authors":"Paul E Moore, Lystra P Hayden, Natalie M Villafranco, Demet Toprak, Jessica L Rice, Lawrence M Rhein, Antonia P Popova, Robin L McKinney, Winston M Manimtim, Jonathan C Levin, Khanh V Lai, Susan C Gage, Manvi Bansal, Christopher D Baker, Eric D Austin, Amit Agarwal, Sharon A McGrath-Morrow, Joseph M Collaco","doi":"10.1002/ppul.27296","DOIUrl":"https://doi.org/10.1002/ppul.27296","url":null,"abstract":"Background: Bronchopulmonary dysplasia, a sequela of preterm birth, is the most common chronic respiratory disorder in infancy, and the second most common in children. Despite this, clinical care remains highly variable with guidelines supported by limited evidence, and do not provide specific guidance for timing of clinical follow-up, echocardiography, modalities of pulmonary function testing, etc. OBJECTIVE/METHODS: To further our understanding of care delivery for BPD, we sought to describe outpatient care patterns at tertiary care centers through survey data from 27 well-established BPD programs.Results: We observed variability in referral patterns to outpatient BPD clinics, ancillary services provided, indications for follow-up echocardiograms, availability of lung function testing, and criteria for discharge from care.Conclusion: More comprehensive and detailed clinical guidelines similar to other pulmonary diseases such as asthma and cystic fibrosis should be developed to help standardize care and may improve long term outcomes.","PeriodicalId":19932,"journal":{"name":"Pediatric Pulmonology","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142400955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Haemophilus influenzae and pneumococci: Co-colonization, interactions, cooperation and competition. 流感嗜血杆菌和肺炎球菌：共居、相互作用、合作与竞争。

IF 2.7 3区医学

Pediatric Pulmonology Pub Date : 2024-10-11 DOI: 10.1002/ppul.27318

Finn McMahon, Robert S Ware, Keith Grimwood, John M Atack

{"title":"Haemophilus influenzae and pneumococci: Co-colonization, interactions, cooperation and competition.","authors":"Finn McMahon, Robert S Ware, Keith Grimwood, John M Atack","doi":"10.1002/ppul.27318","DOIUrl":"10.1002/ppul.27318","url":null,"abstract":"Nontypeable Haemophilus influenzae (NTHi) and Streptococcus pneumoniae (pneumococcus) are pathobionts that share common environmental niches within the upper respiratory tract. They can form part of the resident upper airway microbiota, but under certain environmental circumstances become pathogenic and induce disease. In children, both organisms have a considerable impact on the healthcare system, commonly causing acute otitis media and pneumonia. They are also associated with chronic biofilm-mediated respiratory infections, such as persistent middle ear effusions and chronic suppurative otitis media, and in the lower airways with protracted bacterial bronchitis and bronchiectasis. Consequently, both organisms are responsible for large numbers of antibiotic prescriptions and substantial healthcare costs. The complex relationship between NTHi and pneumococcal co-interaction during colonization, infection and biofilm formation is poorly understood and a greater understanding is needed to facilitate development of future therapies, and novel interventions and prevention strategies. Co-infections with both bacteria can result in more severe disease, with disease severity likely mediated by their ability to cooperate in some in vivo niches. However, this relationship is not always straightforward, as under certain conditions, these two bacteria compete rather than cooperate. Current opinion supports developing a vaccine targeting NTHi strains, as well as a combined vaccine targeting both NTHi and pneumococci to decrease the respiratory disease burden in young children. This review summarizes our current knowledge of the interactions between NTHi and pneumococci and speculates on the future directions of research to understand how these bacteria co-exist and how to better prevent and treat NTHi and pneumococcal infection.","PeriodicalId":19932,"journal":{"name":"Pediatric Pulmonology","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142400954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pneumothorax as the first presentation of multiple exostosis. 气胸是多发性外骨质增生的首发症状。

IF 2.7 3区医学

Pediatric Pulmonology Pub Date : 2024-10-10 DOI: 10.1002/ppul.27316

Lana Khoury, Maysaa Jabarin, Mohamad Hamad Saied

引用次数: 0

Medical and social factors associated with prolonged length of stay for chronically ventilated children. 与长期接受通气治疗的儿童住院时间延长相关的医疗和社会因素。

IF 2.7 3区医学

Pediatric Pulmonology Pub Date : 2024-10-10 DOI: 10.1002/ppul.27320

Katelyn G Enzer, Jessica A Dawson, Jessalyn A Langevin, John T Brinton, Christopher D Baker

{"title":"Medical and social factors associated with prolonged length of stay for chronically ventilated children.","authors":"Katelyn G Enzer, Jessica A Dawson, Jessalyn A Langevin, John T Brinton, Christopher D Baker","doi":"10.1002/ppul.27320","DOIUrl":"https://doi.org/10.1002/ppul.27320","url":null,"abstract":"Objectives: This study seeks to determine the overall and post-intensive care unit (ICU) length of stay (LOS) for children with tracheostomies and chronic mechanical ventilation. We hypothesized that medical and social factors would be associated with prolonged LOS.Study design: This single-center retrospective review included children who were discharged after initiation of chronic ventilation via tracheostomy over an 8-year period (2015-2022). Patients were divided into two groups for analysis, those who had been previously home before admission (HBA) and those who had not (Not HBA). Medical and social determinants of health (SDOH) data were obtained from the electronic medical record for univariate and multivariable analyses.Results: A total of 161 patients were included. HBA subjects (n = 52) were expectedly older at the time of tracheostomy. Not HBA subjects (n = 109) were more likely to be born prematurely and have sequelae of premature birth. Overall and post-ICU LOS increased for both groups during the study period. In the HBA subgroup, congenital heart disease and younger age were associated with longer overall LOS with these factors and the absence of gastric fundoplication being associated with longer post-ICU LOS. For Not HBA patients, younger age, pulmonary hypertension, seizures, and several SDOH were associated with longer overall LOS, whereas only SDOH were associated with a longer post-ICU LOS.Conclusions: Overall and post-ICU LOS for all children hospitalized for tracheostomy and chronic mechanical ventilation are increasing. Prolonged LOS is significantly associated with several medical factors and SDOH.","PeriodicalId":19932,"journal":{"name":"Pediatric Pulmonology","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142472195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Children interstitial lung disease: Assessment and management. 儿童间质性肺病：评估与管理。

IF 2.7 3区医学

Pediatric Pulmonology Pub Date : 2024-10-09 DOI: 10.1002/ppul.27261

Antonio Moreno-Galdo, Ignacio Iglesias-Serrano, Sandra Rovira-Amigo, Alba Torrent-Vernetta

{"title":"Children interstitial lung disease: Assessment and management.","authors":"Antonio Moreno-Galdo, Ignacio Iglesias-Serrano, Sandra Rovira-Amigo, Alba Torrent-Vernetta","doi":"10.1002/ppul.27261","DOIUrl":"https://doi.org/10.1002/ppul.27261","url":null,"abstract":"Diffuse parenchymal lung diseases or children interstitial lung disease (chILD) in pediatrics are a heterogenous group of more than 200 rare diseases with an incidence and prevalence around 8.2 and 46.4 cases/million, respectively, higher than previously recognized, probably related to a greater understanding and increased clinical awareness of these diseases. Children under 2 years of age account for 40%-60% of cases. Diseases presenting before the age of 2 years are mainly of genetic origin or associated with disorders of lung development and are very different from those of older children and adults. In 10%-20% of cases, a genetic cause is found, and in approximately 12%, no cause (undefined chILD) is found after performing all diagnostic tests. A multidisciplinary approach in an expert center is essential for diagnosis and treatment. Tests to be performed after lung computed tomography include serological and other blood tests, bronchoscopy and bronchoalveolar lavage, genetic studies and lung biopsy. Although no approved specific treatment for most cases of chILD exists, an improved understanding of the pathophysiology of many of these diseases is facilitating the development of new treatments.","PeriodicalId":19932,"journal":{"name":"Pediatric Pulmonology","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142392401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0