Pediatric Pulmonology最新文献_第10页

Advances in the restoration of CFTR in children and pwCF with "mild disease". 在恢复患有 "轻度疾病 "的儿童和儿童先天性心脏病 CFTR 方面取得的进展。

IF 2.7 3区医学

Pediatric Pulmonology Pub Date : 2025-03-01 Epub Date: 2024-11-11 DOI: 10.1002/ppul.27359

Malena Cohen-Cymberknoh

引用次数: 0

Treatment of OSA beyond adenotonsillectomy. 腺扁桃体切除术之外的 OSA 治疗。

IF 2.7 3区医学

Pediatric Pulmonology Pub Date : 2025-03-01 Epub Date: 2024-10-22 DOI: 10.1002/ppul.27297

Joel Reiter

引用次数: 0

Viral: Bacterial interactions in childhood asthma. 病毒儿童哮喘中的细菌相互作用

IF 2.7 3区医学

Pediatric Pulmonology Pub Date : 2025-03-01 Epub Date: 2024-10-22 DOI: 10.1002/ppul.27280

Peter D Sly

引用次数: 0

Indoor air pollution and its impact on the lungs. 室内空气污染及其对肺部的影响。

IF 2.7 3区医学

Pediatric Pulmonology Pub Date : 2025-03-01 Epub Date: 2024-10-03 DOI: 10.1002/ppul.27281

Peter D Sly

引用次数: 0

Bridging the Gap in Neonatal Care: Evaluating AI Chatbots for Chronic Neonatal Lung Disease and Home Oxygen Therapy Management.

IF 2.7 3区医学

Pediatric Pulmonology Pub Date : 2025-03-01 DOI: 10.1002/ppul.71020

Weiqin Liu, Hong Wei, Lingling Xiang, Yin Liu, Chunyi Wang, Ziyu Hua

{"title":"Bridging the Gap in Neonatal Care: Evaluating AI Chatbots for Chronic Neonatal Lung Disease and Home Oxygen Therapy Management.","authors":"Weiqin Liu, Hong Wei, Lingling Xiang, Yin Liu, Chunyi Wang, Ziyu Hua","doi":"10.1002/ppul.71020","DOIUrl":"https://doi.org/10.1002/ppul.71020","url":null,"abstract":"Objective: To evaluate the accuracy and comprehensiveness of eight free, publicly available large language model (LLM) chatbots in addressing common questions related to chronic neonatal lung disease (CNLD) and home oxygen therapy (HOT).Study design: Twenty CNLD and HOT-related questions were curated across nine domains. Responses from ChatGPT-3.5, Google Bard, Bing Chat, Claude 3.5 Sonnet, ERNIE Bot 3.5, and GLM-4 were generated and evaluated by three experienced neonatologists using Likert scales for accuracy and comprehensiveness. Updated LLM models (ChatGPT-4o mini and Gemini 2.0 Flash Experimental) were incorporated to assess rapid technological advancement. Statistical analyses included ANOVA, Kruskal-Wallis tests, and intraclass correlation coefficients.Results: Bing Chat and Claude 3.5 Sonnet demonstrated superior performance, with the highest mean accuracy scores (5.78 ± 0.48 and 5.75 ± 0.54, respectively) and competence scores (2.65 ± 0.58 and 2.80 ± 0.41, respectively). In subsequent testing, Gemini 2.0 Flash Experimental and ChatGPT-4o mini achieved comparable high performance. Performance varied across domains, with all models excelling in \"equipment and safety protocols\" and \"caregiver support.\" ERNIE Bot 3.5 and GLM-4 showed self-correction capabilities when prompted.Conclusions: LLMs promise accurate CNLD/HOT information. However, performance variability and the risk of misinformation necessitate expert oversight and continued refinement before widespread clinical implementation.","PeriodicalId":19932,"journal":{"name":"Pediatric Pulmonology","volume":"60 3","pages":"e71020"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Outpatient Respiratory Outcomes in Extremely Preterm Children During the First 3 Years of Life.

IF 2.7 3区医学

Pediatric Pulmonology Pub Date : 2025-03-01 DOI: 10.1002/ppul.71025

Cynara Leon, Pallavi Kawatra, Amanda Martin, Brianna Aoyama, Joseph M Collaco, Sharon A McGrath-Morrow

{"title":"Outpatient Respiratory Outcomes in Extremely Preterm Children During the First 3 Years of Life.","authors":"Cynara Leon, Pallavi Kawatra, Amanda Martin, Brianna Aoyama, Joseph M Collaco, Sharon A McGrath-Morrow","doi":"10.1002/ppul.71025","DOIUrl":"10.1002/ppul.71025","url":null,"abstract":"Rationale: Extremely preterm infants are at highest risk for developing bronchopulmonary dysplasia (BPD). This study aimed to examine the relationship between gestational age and respiratory outcomes in children with BPD in the outpatient setting.Methods: Data were collected from 1025 preterm children with BPD recruited from outpatient bronchopulmonary (BPD) clinics at Johns Hopkins and Children's Hospital of Philadelphia (CHOP). Extremely preterm children (22-24 and 25-27 weeks gestation) were compared to a reference group of very preterm children (28-32 weeks gestation). Data were analyzed using Χ2 tests, t-tests, and ANOVA tests.Results: Infants born at < 25 weeks gestation were more likely to have severe BPD (71.9%), be discharged on supplemental oxygen (50.7%), have public insurance, and self-report as Black (60.4%) compared to those born > 25 weeks. In the outpatient setting, extremely preterm children (22-24 weeks gestation) had a higher likelihood of activity limitation (OR 1.72) compared to very preterm infants. Hispanic children, regardless of gestational age, were more likely to have sick visits (OR 2.09) and a hospital admission (OR 2.15) compared to non-Hispanic children. Children with public insurance had a higher likelihood of ED visits (OR 1.48), hospital admissions (OR 1.49), systemic steroid use (OR 1.39), nighttime respiratory symptoms (OR 1.66), and activity limitations (OR 1.61) compared to privately insured children.Conclusions: After initial hospital discharge, extremely preterm children (22-24 weeks gestation) have a higher likelihood of activity limitation. However, other factors including race/ethnicity and public insurance are more likely driving outpatient respiratory outcomes regardless of gestational age.","PeriodicalId":19932,"journal":{"name":"Pediatric Pulmonology","volume":"60 3","pages":"e71025"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11955149/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143573642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Do We Still Need a Definition Size in Pediatric Primary Spontaneous Pneumothorax? A Plea for Management Standardization.

IF 2.7 3区医学

Pediatric Pulmonology Pub Date : 2025-03-01 DOI: 10.1002/ppul.71047

Gaia Paolella, Giovanni Rollo, Angelo Zarfati, Leonardo Crescentini, Arianna Bertocchini, Silvia Madafferi, Antonella Accinni, Chiara Grimaldi, Giorgio Persano, Alessandro Crocoli, Valerio Pardi, Ivan Pietro Aloi

引用次数: 0

How Families Manage the Home Environment for Young People With Asthma and Allergic Sensitisation: A Qualitative Study.

IF 2.7 3区医学

Pediatric Pulmonology Pub Date : 2025-03-01 DOI: 10.1002/ppul.71013

Grace Lewis, Linda Milnes, Jürgen Schwarze, Alexandra Adams, Alistair Duff

{"title":"How Families Manage the Home Environment for Young People With Asthma and Allergic Sensitisation: A Qualitative Study.","authors":"Grace Lewis, Linda Milnes, Jürgen Schwarze, Alexandra Adams, Alistair Duff","doi":"10.1002/ppul.71013","DOIUrl":"10.1002/ppul.71013","url":null,"abstract":"Background and aim: Children and young people (CYP) with severe, sub-optimally controlled asthma and co-existing allergic senitization to indoor aeroallergens, such as pet dander and house dust mite (HDM), would likely benefit from reduced allergen exposure. Multiple allergen remediation interventions exist and are often suggested to families in secondary care asthma clinics in the United Kingdom. Evidence suggests remediation uptake is low or partial but there is sparse evidence to explain why. This study aims to explain how families in this situation make decisions about home-based allergen remediations.Methods: In-depth qualitative interviews with CYP and mothers were analyzed, and a grounded theory approach was used to develop a theory to explain decision-making processes and behaviors.Results: Ten CYP aged 11-15 years and 11 mothers were interviewed. The core finding was that families iteratively respond to changes in how certain they are in their asthma management decisions and actions. For allergen remediation uptake, this certainty varied depending on seeing an outcome-exposure relationship, understanding asthma severity, variability, and asthma control at the time of remediation decision-making. Understanding the mechanistic role of allergen exposures in asthma was challenging for families, and ongoing bi-directional communication with clinicians was essential in supporting long-term decision-making.Conclusion: The theory explains the often elongated, reactive process of allergen remediation decision making and implementation. It also explains other elements of family management of asthma, and their interconnections. Families' iterative responsiveness suggests opportunities to intervene and promote earlier, preventative behavior change.","PeriodicalId":19932,"journal":{"name":"Pediatric Pulmonology","volume":"60 3","pages":"e71013"},"PeriodicalIF":2.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11898542/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pediatric lung ultrasound. 小儿肺部超声波

IF 2.7 3区医学

Pediatric Pulmonology Pub Date : 2025-03-01 Epub Date: 2024-10-25 DOI: 10.1002/ppul.27302

Ioana Ciuca

引用次数: 0

A Novel Treatment of STING-Associated Vasculopathy With Onset in Infancy. 治疗婴儿期发病的 STING 相关血管病的新方法

IF 2.7 3区医学

Pediatric Pulmonology Pub Date : 2025-03-01 DOI: 10.1002/ppul.71052

Katarzyna Solarska-Rydz, Honorata Marczak, Marek Kulus, Katarzyna Krenke

引用次数: 0