Pediatric Pulmonology最新文献_第2页

Xe Ventilation and Gas-Exchange MRI Abnormalities in Children with Neuroendocrine Cell Hyperplasia of Infancy (NEHI). 婴儿神经内分泌细胞增生症（NEHI）患儿的 Xe 通气和气体交换 MRI 异常。

IF 2.7 3区医学

Pediatric Pulmonology Pub Date : 2024-11-18 DOI: 10.1002/ppul.27410

Melanie A Anderson, Bilal I Masokano, Joseph W Plummer, Matthew M Willmering, Katelyn Krivchenia, Christopher T Towe, Laura L Walkup

引用次数: 0

Exploring Ultrasonographic Diaphragmatic Function in Children With Cerebral Palsy. 探索脑瘫儿童的超声膈肌功能。

IF 2.7 3区医学

Pediatric Pulmonology Pub Date : 2024-11-18 DOI: 10.1002/ppul.27407

Maracy Balbino Morgado Sobreira, Thálita Raysa de Lima Crispim, Renata do Nascimento Silva, Francisco Locks, Helga Cecília Muniz de Souza, Paulo André Freire Magalhães

引用次数: 0

Pulmonary manifestations of juvenile vs. adult systemic sclerosis: insights into pathophysiological and clinical features. 幼年系统性硬化症与成年系统性硬化症的肺部表现：病理生理学和临床特征研究。

IF 2.7 3区医学

Pediatric Pulmonology Pub Date : 2024-11-15 DOI: 10.1002/ppul.27347

Gabriele Di Pasquale, Nicholas Caione, Alessio Di Berardino, Giulio Di Donato

引用次数: 0

Correction to "Reference Values for Respiratory Sinusoidal Oscillometry in Children Aged 3 to 17 Years". 更正 "3 至 17 岁儿童呼吸窦性振荡测量参考值"。

IF 2.7 3区医学

Pediatric Pulmonology Pub Date : 2024-11-15 DOI: 10.1002/ppul.27409

引用次数: 0

E-Cigarettes and Cystic Fibrosis-Current Perceptions and Future Directions. 电子烟与囊性纤维化--当前的看法和未来的方向。

IF 2.7 3区医学

Pediatric Pulmonology Pub Date : 2024-11-15 DOI: 10.1002/ppul.27406

Maryam Sahibqran, Gordon MacGregor, Louise Thomson, Patrick McCrossan, Anne Devenny, Ross J Langley

引用次数: 0

Exploring Risk Factors Associated With Intensive Care Unit Admission in a Retrospective Cohort of 631 Children With Bronchiolitis. 在 631 名支气管炎患儿的回顾性队列中探索与入住重症监护室相关的风险因素。

IF 2.7 3区医学

Pediatric Pulmonology Pub Date : 2024-11-15 DOI: 10.1002/ppul.27394

Valentina Guarnieri, Giordano Palmas, Sandra Trapani, Antonella Mollo, Chiara Macucci, Irene Gambini, Valentina Mottola, Chiara Rubino, Maria Moriondo, Francesco Nieddu, Silvia Ricci, Chiara Azzari, Giuseppe Indolfi

{"title":"Exploring Risk Factors Associated With Intensive Care Unit Admission in a Retrospective Cohort of 631 Children With Bronchiolitis.","authors":"Valentina Guarnieri, Giordano Palmas, Sandra Trapani, Antonella Mollo, Chiara Macucci, Irene Gambini, Valentina Mottola, Chiara Rubino, Maria Moriondo, Francesco Nieddu, Silvia Ricci, Chiara Azzari, Giuseppe Indolfi","doi":"10.1002/ppul.27394","DOIUrl":"https://doi.org/10.1002/ppul.27394","url":null,"abstract":"Aim: Examine the trends and epidemiological features of acute hospitalized bronchiolitis cases among children aged 28 days to 2 years, both before and after the COVID-19 pandemic. Furthermore, evaluate their need for intensive care unit (ICU) admission and identify primary risk factors associated with severe bronchiolitis.Methods: A retrospective analysis was conducted on the medical records of paediatric patients admitted to Meyer Children's Hospital in Florence (Italy) from September 2019 to March 2023, with the diagnosis of bronchiolitis.Results: Between 2019 and 2023, bronchiolitis hospitalizations grew by 76%, going from 131 to 230 cases, after the historical minimum of 14 cases in the 2020-2021 season. Respiratory syncytial virus (RSV) infection emerged as the predominant etiological agent, contributing to 76% of hospitalizations in both 2021-2022 and 2022-2023 seasons. Coinfection cases increased fivefold from 2019 to 2023, accounting for 23% of hospitalizations in 2022-2023. In addition, the ICU admission rate increased from 13% in 2019-2020 to 31% of bronchiolitis hospitalizations in 2022-2023. Univariate and multivariate analysis data show that infants below 2 months of age, preterm births, comorbidities and RSV infections were correlated with a higher risk for ICU admission.Conclusion: The growing trend in ICU admissions for acute bronchiolitis in hospitalized children represents a substantial health challenge. Addressing the bronchiolitis epidemic necessitates a strategic focus on RSV prevention through interventions such as vaccines and monoclonal antibodies. Urgent implementation of preventive initiatives, together with continuous surveillance and the establishment of national databases, is imperative and cannot be further deferred.","PeriodicalId":19932,"journal":{"name":"Pediatric Pulmonology","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142639411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

E-Cigarette Addiction in Adolescents-How Do We Get Them to Stop? 青少年吸电子烟成瘾--我们如何让他们戒烟？

IF 2.7 3区医学

Pediatric Pulmonology Pub Date : 2024-11-14 DOI: 10.1002/ppul.27403

Elizabeth Watt, Andy Bush, Janet Gardner-Medwin, Ross J Langley

{"title":"E-Cigarette Addiction in Adolescents-How Do We Get Them to Stop?","authors":"Elizabeth Watt, Andy Bush, Janet Gardner-Medwin, Ross J Langley","doi":"10.1002/ppul.27403","DOIUrl":"https://doi.org/10.1002/ppul.27403","url":null,"abstract":"Background: E-cigarette use in adolescents is increasing and the addictive potential of these devices is well recognised. Most health authorities have no E-cigarette cessation programmes. We reviewed randomised control trials evaluating prevention strategies for adolescent E-cigarette use and identified any successful components.Methods: Search terms were created in accordance with the main objective (vaping/E-cigarette use prevention/cessation/adolescents). Search was conducted via Ovid MedLine for English-language randomised control trials published from 2020 to 2023 containing keywords relating to adolescent E-cigarette use. Seven U.S. studies were included in the review. We established common themes of qualitative outcomes and identification of successful components of prevention programmes.Results: Interventions showed significant improvement in general knowledge and perceived risk of E-cigarettes, and lower risk of using other tobacco products. Other consequences showed lower susceptibility to vaping uptake and higher abstinence rates although future studies are required to see if these were sustained long-term.Conclusion: Focus groups aid development of cessation and prevention campaigns. Messages should be digital and relatable. Messages should contain health \"harm\" warnings. Furthermore, support services should be well-signposted for adolescents. Social media is a low-cost and important tool to halt teenage E-cigarette addiction.","PeriodicalId":19932,"journal":{"name":"Pediatric Pulmonology","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142625754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Postnatal Growth Trajectories and Risk of Obstructive Sleep Apnea in Middle Age: A Cohort Study. 产后生长轨迹与中年期阻塞性睡眠呼吸暂停的风险：一项队列研究

IF 2.7 3区医学

Pediatric Pulmonology Pub Date : 2024-11-13 DOI: 10.1002/ppul.27396

Tejas Menon Suri, Sumit Bhargava, Kappadan Tharammal Akshara, Sikha Sinha, Vani Aggarwal, Kali Das Gupta, Gurpreet Singh, Bhaskar Singh, Lakshmy Ramakrishnan, Clive Osmond, Caroline H D Fall, Santosh K Bhargava, Harshpal Singh Sachdev

{"title":"Postnatal Growth Trajectories and Risk of Obstructive Sleep Apnea in Middle Age: A Cohort Study.","authors":"Tejas Menon Suri, Sumit Bhargava, Kappadan Tharammal Akshara, Sikha Sinha, Vani Aggarwal, Kali Das Gupta, Gurpreet Singh, Bhaskar Singh, Lakshmy Ramakrishnan, Clive Osmond, Caroline H D Fall, Santosh K Bhargava, Harshpal Singh Sachdev","doi":"10.1002/ppul.27396","DOIUrl":"https://doi.org/10.1002/ppul.27396","url":null,"abstract":"Study objectives: Rapid growth in childhood predisposes to obesity and cardiometabolic diseases in adulthood. While obstructive sleep apnea (OSA) is bidirectionally linked to obesity, its developmental origins are sparsely studied. We examined associations between postnatal growth and the risk of OSA in adulthood.Methods: We included adults whose childhood anthropometric data was collected in the New Delhi Birth Cohort study. The risk of OSA was defined by the Berlin Questionnaire (BQ) with and without the obesity criterion. Using logistic regression, we studied associations of OSA risk with conditional growth parameters, which are statistically independent measures of gain in height, weight, and body mass index (BMI), during infancy (0-2 years), early childhood (2-5 years), and late childhood (5-11 years).Results: Among 521 subjects (58.9% males) with a mean (SD) age of 40.9 (1.7) years, 30.9% had a high risk of OSA. On multivariate analysis, a high risk of OSA was associated with a higher conditional BMI in infancy (odds ratio: 1.25; 95% confidence interval: 1.00-1.57; p = 0.048) and early childhood (1.35; 1.07-1.69; p = 0.011). Higher risk of OSA was associated with greater conditional weight in early childhood (1.34; 1.06-1.68; p = 0.013). Using the modified BQ definition without obesity, adult risk of OSA was significantly associated with a higher adult BMI instead of childhood conditional BMIs.Conclusions: Greater gain in conditional BMI or weight in early childhood is associated with a high risk of OSA in middle age, which is mediated by a higher attained adult BMI.","PeriodicalId":19932,"journal":{"name":"Pediatric Pulmonology","volume":" ","pages":"e27396"},"PeriodicalIF":2.7,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142625850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Secretion Movement During Mechanical Ventilation Superimposed on Intrapulmonary Percussive Ventilation (IPV) Versus Continuous High-Frequency Oscillation (CHFO): A Bench Study. 肺内冲击通气（IPV）与持续高频振荡（CHFO）在机械通气过程中的分泌物运动：台架研究。

IF 2.7 3区医学

Pediatric Pulmonology Pub Date : 2024-11-13 DOI: 10.1002/ppul.27404

Ping-Hui Liu, Anita Arnsperger

引用次数: 0

Mental Health of Pediatric Patients with Cystic Fibrosis after 18 Months on Elexacaftor-Tezacaftor-Ivacaftor Therapy. 接受 Elexacaftor-Tezacaftor-Ivacaftor 治疗 18 个月后囊性纤维化儿科患者的心理健康。

IF 2.7 3区医学

Pediatric Pulmonology Pub Date : 2024-11-13 DOI: 10.1002/ppul.27393

Kimberly Pasley, Mariah Eisner, Stephanie Sliemers, Rylie Young, Mary Lynn Dell, Karen S McCoy, Anne May

{"title":"Mental Health of Pediatric Patients with Cystic Fibrosis after 18 Months on Elexacaftor-Tezacaftor-Ivacaftor Therapy.","authors":"Kimberly Pasley, Mariah Eisner, Stephanie Sliemers, Rylie Young, Mary Lynn Dell, Karen S McCoy, Anne May","doi":"10.1002/ppul.27393","DOIUrl":"https://doi.org/10.1002/ppul.27393","url":null,"abstract":"Background: Research studies are conflicting regarding new highly effective modulators and the association with mental health symptoms for adults and adolescents with cystic fibrosis (CF). For younger children, small studies and case reports indicate a wide range of effects, ranging from improvement in mood to the development of neuropsychiatric symptoms. However, a large placebo-controlled study indicated no causal connection. This study evaluates the frequency and severity of mental health symptoms in children and adolescents while taking elexacaftor/tezacaftor/ivacaftor (ETI).Methods: The study includes 81 pediatric patients with CF followed at Nationwide Children's Hospital (NCH). Patient Reported Outcomes Measurement Information System (PROMIS)-Anxiety and Depression, Patient Health Questionnaire 8 (PHQ-8) and Generalized Anxiety Disorder Questionnaire (GAD-7) were used to screen for depression and anxiety. Age-appropriate questionnaires were completed over the first 18 months after initiating ETI.Results: At baseline, majority of participants reported mental health symptoms within normal limits (WNL). For participants with elevated baseline measures, depressive and anxiety symptoms significantly decreased throughout the study period. Depending on the metric, patients experiencing depressive and anxiety symptoms dropped to 2-3% (n = 1, on each depressive measure) and 0% (n = 0, on either anxiety measures) respectively by 18 months.Conclusion: Most pediatric patients with CF did not endorse symptoms of depression or anxiety disorders at ETI initiation. Over the first 18 months of ETI usage, the percentage of patients with these symptoms decreased, suggesting that the percentage of patients experiencing severe symptoms of depression and anxiety may decrease with ongoing use of ETI.","PeriodicalId":19932,"journal":{"name":"Pediatric Pulmonology","volume":" ","pages":"e27393"},"PeriodicalIF":2.7,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142625781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0