Pediatric Pulmonology最新文献_第3页

Distance to Primary Care/Pharmacies Does Not Affect Outpatient Bronchopulmonary Dysplasia Outcomes. 到初级保健/药房的距离不影响门诊支气管肺发育不良的结果。

IF 2.4 3区医学

Pediatric Pulmonology Pub Date : 2026-10-01 DOI: 10.1002/ppul.71871

Noah D Christian, Anant Mashalkar, Sharon A McGrath-Morrow, Joseph M Collaco, Brianna C Aoyama

引用次数: 0

Safety of a 4-Week Pediatric Home Mechanical Ventilated Pathway-A Single Center's Retrospective Study. 4周儿童家庭机械通气通道的安全性——单中心回顾性研究

IF 2.4 3区医学

Pediatric Pulmonology Pub Date : 2026-10-01 DOI: 10.1002/ppul.71842

Derek Corpus, Laura Lazzarini Wo, Josephine Ellashek, Sarah Heinonen, Andrea Connelly, Sheila Kun, Sasha Singh, Lisa Barrios, Gabriel Costea, Danielle Mountan, Manvi Bansal, Roberta M Kato

{"title":"Safety of a 4-Week Pediatric Home Mechanical Ventilated Pathway-A Single Center's Retrospective Study.","authors":"Derek Corpus, Laura Lazzarini Wo, Josephine Ellashek, Sarah Heinonen, Andrea Connelly, Sheila Kun, Sasha Singh, Lisa Barrios, Gabriel Costea, Danielle Mountan, Manvi Bansal, Roberta M Kato","doi":"10.1002/ppul.71842","DOIUrl":"https://doi.org/10.1002/ppul.71842","url":null,"abstract":"Background/objective: Pediatric Home Mechanical Ventilator (HMV) Programs have supported children with chronic respiratory failure since the 1970s, yet optimal caregiver training duration remains unclear. This study evaluated the safety and effectiveness of a standardized 4-week HMV multidisciplinary action plan (HMV MAP) by analyzing hospital length of stay (LOS) and 30-day revisit rates.Methods: A retrospective cohort study was conducted at a single center, including 59 children (ages 0-21) with tracheostomy and chronic home ventilator use who completed the HMV MAP training between 2016 and 2021. Data were extracted from electronic medical records. Existing home ventilator-dependent patients re-admitted for any reason, HMV MAP patients on palliative, hospice and/or concurrent care for home, as well as patients discharged to long-term care facilities/subacute care facilities were excluded.Results: Of 59 eligible patients, the most common indication for long-term mechanical ventilation was chronic respiratory failure due to respiratory insufficiency. The HMV MAP median LOS was 37 days (IQR: 12-92). There were 30 patients who had extended LOS (eLOS HMV MAP). Of these, 21 were due to non-respiratory causes, with 14 being medical-related and 7 being social-related. Among patients discharged in 4 weeks, 0% had ED visits within 48 h of discharge, 17% were readmitted within 30 days for respiratory complications and 6.9% for non-respiratory complications; compared to 6.7%, 10% and 10% respectively for eLOS 4 W HMV MAP.Conclusions: The HMV MAP appears safe and effective, with low early ED visits and readmission rates. Most discharge delays were due to non-respiratory factors, suggesting the pathway may benefit from flexibility to accommodate medical and social complexities.","PeriodicalId":19932,"journal":{"name":"Pediatric Pulmonology","volume":"61 10","pages":"e71842"},"PeriodicalIF":2.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149112926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Response to Commentary: Diaphragmatic Atrophy After Pediatric Cardiac Surgery: Toward Integrated Monitoring. 对评论的回应：儿童心脏手术后膈肌萎缩：迈向综合监测。

IF 2.4 3区医学

Pediatric Pulmonology Pub Date : 2026-10-01 DOI: 10.1002/ppul.71821

Clarice Laroque Sinott Lopes, Jefferson Pedro Piva

引用次数: 0

Beyond Snoring, Sleepiness and Surgery: Update on the Prevalent Symptoms of and Treatment Effects in all Age Groups With Pediatric Obstructive Sleep Apnea. 除了打鼾，嗜睡和手术：所有年龄组儿童阻塞性睡眠呼吸暂停的流行症状和治疗效果的最新进展。

IF 2.4 3区医学

Pediatric Pulmonology Pub Date : 2026-10-01 DOI: 10.1002/ppul.71865

Amanda B Hassinger, Hannah Granger, Alexa Ibrahim, Stacey Li, Mine Varol, Aysenur Danis

{"title":"Beyond Snoring, Sleepiness and Surgery: Update on the Prevalent Symptoms of and Treatment Effects in all Age Groups With Pediatric Obstructive Sleep Apnea.","authors":"Amanda B Hassinger, Hannah Granger, Alexa Ibrahim, Stacey Li, Mine Varol, Aysenur Danis","doi":"10.1002/ppul.71865","DOIUrl":"https://doi.org/10.1002/ppul.71865","url":null,"abstract":"Introduction: Screening and treatments for pediatric obstructive sleep apnea (pOSA) often use adult symptoms and conventional surgical approaches. This study tested the hypothesis that symptoms and treatment efficacy for OSA differ across age groups.Methods: Single-center cohort study of 0 to 18-year-olds who were managed and underwent polysomnography (PSG) in a pediatric-dedicated sleep medicine center from 2020 to 2024.Results: Of 491 children, 489 had pOSA, 57.7% were male, the median age was 6 years old (IQR1-3, 4-9), and 41% already had an adeno- or adenotonsillectomy prior to the PSG. Only 15.6% were obese, and 13.2% had an Epworth Sleepiness Score over 10. Snoring was not the most prevalent nocturnal symptom: restlessness (91.6%), chronic insomnia (86.1%), kicking legs (82.0%), and frequent awakening (78.4%) were all more common. Neurocognitive issues, present in 93.7%, were most commonly mood swings (86.5%) and ADHD (51.9%). Of the 270 without surgery before the PSG, 72.2% (n = 195) were referred, and 173 had surgery. Positive airway pressure (PAP) was prescribed for 240 (49.1%) patients, 176 (73%) of whom had enough CPAP usage to provide machine-estimated apnea-hypopnea index (AHI). After adenotonsillectomy, 27.0% had a post-operative AHI under 5 events per hour, and 73.1% had improvement in neurocognitive issues while that was 94.9% and 87.2% in those using PAP, respectively. After adjusting for age and AHI, PAP had threefold (aOR 3.85, 95%CI 1.39-10.67) higher odds of improving neurocognitive issues than surgery, p = 0.010.Conclusions: The majority of children with pOSA are not tired or obese. Insomnia and restless sleep are more common than snoring. Daytime neurocognitive issues affect almost all children with pOSA and improve with treatment, especially PAP.","PeriodicalId":19932,"journal":{"name":"Pediatric Pulmonology","volume":"61 10","pages":"e71865"},"PeriodicalIF":2.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149113490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

When Three Diseases Collide: Human Immunodeficiency Virus, Hodgkin Lymphoma, and Tuberculosis in a Young Child. 当三种疾病碰撞：人类免疫缺陷病毒、霍奇金淋巴瘤和儿童结核病。

IF 2.4 3区医学

Pediatric Pulmonology Pub Date : 2026-10-01 DOI: 10.1002/ppul.71867

Pierre Goussard, Leilah Schoonraad, Celeste Burger, André Gie, Pawel Schubert, Anel van Zyl

引用次数: 0

Comment on "Function and Structure Relationships With Inflammation Differ in Two Chronic Suppurative Lung Diseases". 《两种慢性化脓性肺疾病与炎症的功能、结构关系不同》述评

IF 2.4 3区医学

Pediatric Pulmonology Pub Date : 2026-10-01 DOI: 10.1002/ppul.71862

Neeraj Singh, Monika Srivastav

引用次数: 0

Navigating School While Living With Cystic Fibrosis: Barriers and Support Strategies From the Patient and Family Perspective. 与囊性纤维化一起生活的学校导航：从患者和家庭的角度来看障碍和支持策略。

IF 2.4 3区医学

Pediatric Pulmonology Pub Date : 2026-10-01 DOI: 10.1002/ppul.71870

Katelyn Heimbruch, Sarah Strong, Matt Wackler, Marissa Taylor, Qing Duan, Stephanie S Filigno, Michelle Hjelm

{"title":"Navigating School While Living With Cystic Fibrosis: Barriers and Support Strategies From the Patient and Family Perspective.","authors":"Katelyn Heimbruch, Sarah Strong, Matt Wackler, Marissa Taylor, Qing Duan, Stephanie S Filigno, Michelle Hjelm","doi":"10.1002/ppul.71870","DOIUrl":"https://doi.org/10.1002/ppul.71870","url":null,"abstract":"Objective: Managing cystic fibrosis (CF) requires balancing medical treatments with age-appropriate activities and responsibilities. Educational success and attainment are predictors of future health and functional outcomes later in life. To optimize educational functioning and provide tailored support, it is essential to understand the unique perspectives and needs of people with CF (PwCF) and their caregivers.Methods: A cross-sectional, survey-based study was conducted in August 2024. The Cystic Fibrosis Foundation distributed the survey electronically via the Community Voice platform, and accredited CF programs distributed the survey to their local families.Results: Survey respondents included 146 PwCF, caregivers and caregiver-PwCF pairs, representing PwCF ages ranging from 2 to 21. Results indicated that PwCF and their caregivers value support from the CF care team to address educational challenges, including frequent absences due to medical appointments, obtaining needed accommodations (i.e., medications and bathroom passes), managing infection control, and the impact of CF-related health issues on academic performance.Conclusion: This study identifies common school-related issues faced by PwCF and caregivers that warrant targeted and proactive attention to support academic achievement and wellbeing. Caregivers and PwCF feel comfortable addressing school-related issues with CF care teams and prefer the care team to initiate conversations about school. Study results emphasize the benefit of having a centralized and comprehensive CF-specific repository that can be easily accessed by care teams to proactively provide tailored resources and information to reduce the burden of school-related issues and consequently promote improved quality of life.","PeriodicalId":19932,"journal":{"name":"Pediatric Pulmonology","volume":"61 10","pages":"e71870"},"PeriodicalIF":2.4,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149183857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Less Invasive Surfactant Administration Using Video Laryngoscope to Decrease Pain in Neonates: A Randomized Controlled Trial. 使用视频喉镜给药减轻新生儿疼痛的微创表面活性剂：一项随机对照试验。

IF 2.4 3区医学

Pediatric Pulmonology Pub Date : 2026-09-01 DOI: 10.1002/ppul.71808

Mude Praneetha, Tapas Som, Pankaj Mohanty, Tanushree Sahoo, Usha Devi R

{"title":"Less Invasive Surfactant Administration Using Video Laryngoscope to Decrease Pain in Neonates: A Randomized Controlled Trial.","authors":"Mude Praneetha, Tapas Som, Pankaj Mohanty, Tanushree Sahoo, Usha Devi R","doi":"10.1002/ppul.71808","DOIUrl":"10.1002/ppul.71808","url":null,"abstract":"Objectives: To assess whether the use of video laryngoscope, when compared to conventional laryngoscope decreases pain (assessed by Faceless Acute Neonatal Pain Scale) in preterm neonates while administering surfactant by LISA.Methods: Preterm neonates < 35 weeks requiring FiO2 > 0.3 on CPAP pressure of at least 6 cm of H2O were administered surfactant by LISA technique either by video laryngoscope (Intervention) or conventional laryngoscope (Control). Faceless Acute Neonatal Pain Scale was used to determine pain 5 min before the procedure, immediately, 5 min, and 10 min after the procedure. The primary outcome was severity of pain; secondary outcomes were time taken to complete the procedure, number of attempts, incidence of IVH, and adverse events during the procedure.Results: In total, 42 neonates of < 35 weeks gestation with comparable baseline demographics were randomized into 2 groups. The median (IQR) FANS score immediately post-procedure in the intervention arm was 2 (2-4) versus 2 (1-4) in the control arm, p = 0.79. There was no statistical difference in the secondary outcomes studied.Conclusion: The two groups had no difference in the pain score. The pain experienced by neonates during the LISA procedure was moderate and of short duration and it did not depend on the type of laryngoscope used. Moderate pain during the procedure can be managed with nonpharmacological measures; thereby, the use of sedatives or analgesics can be avoided, which might be of concern. There was no difference in the number of attempts or in time taken to complete the procedure when performed by neonatologists experienced in using conventional laryngoscopes compared to video laryngoscopes.Trial registration: Clinical Trial Registry of India: CTRI/2022/09/045204 on 05.09.2022.","PeriodicalId":19932,"journal":{"name":"Pediatric Pulmonology","volume":"61 9","pages":"e71808"},"PeriodicalIF":2.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13504638/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148813714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Novel Dosing, Monitoring, and Safety Assessment for Cyclosporine in the Management of ABCA3 Surfactant Dysfunction in an Infant. 环孢素治疗婴儿ABCA3表面活性剂功能障碍的新剂量、监测和安全性评估。

IF 2.4 3区医学

Pediatric Pulmonology Pub Date : 2026-09-01 DOI: 10.1002/ppul.71825

Page Queener, Emma L Ross, Robin Deterding

引用次数: 0

Use of Volume-Targeted Pressure Support in Children With Tracheostomies: A Single-Center Experience. 在气管切开术儿童中使用容积定向压力支持：单中心经验。

IF 2.4 3区医学

Pediatric Pulmonology Pub Date : 2026-09-01 DOI: 10.1002/ppul.71835

Audrey Tilly-Gratton, Jessica A Dawson, Tracy A Edwards, John T Brinton, Christopher D Baker

{"title":"Use of Volume-Targeted Pressure Support in Children With Tracheostomies: A Single-Center Experience.","authors":"Audrey Tilly-Gratton, Jessica A Dawson, Tracy A Edwards, John T Brinton, Christopher D Baker","doi":"10.1002/ppul.71835","DOIUrl":"10.1002/ppul.71835","url":null,"abstract":"Background: Although the literature is limited, volume-targeted pressure support (VT-PS) ventilation has increasingly been used in children with tracheostomies.Objective: To describe a single-center experience using invasive VT-PS in children with tracheostomies.Methods: The Ventilator Care Program registry at Children's Hospital Colorado was used to identify subjects who underwent tracheotomy between 2015 and 2024. Children (≤ 21 years) with chronic mechanical ventilation for ≥ 14 consecutive days were included. Subjects were divided between the \"VT-PS\" (VT-PS ≥ 14 consecutive days or discharged on VT-PS) and \"no VT-PS\" (VT-PS < 14 consecutive days or discharged not on VT-PS) groups.Findings: Three hundred twenty three subjects were mechanically ventilated via tracheostomy during the study period (VT-PS, n = 263 vs. no VT-PS, n = 60). In 2017, VT-PS surpassed synchronized intermittent mandatory ventilation-volume control (SIMV-VC) as the most common mode of ventilation when transitioning to a portable ventilator. VT-PS portable ventilator trials were more likely to be continued until discharge than SIMV-VC trials (52% vs. 27.9% p < 0.001). A transition to VT-PS when previously using another mode on a portable ventilator resulted in a reduction in the patient's respiratory rate (median 33.0 [IQR 25.0-41.5] vs. 31.0 [22.5-39.0], p < 0.001). There was no significant difference in the cumulative incidence of ventilator liberation or decannulation between the two groups.Conclusions and relevance: Our institution's use of VT-PS has shown that this modality is well tolerated in most children with tracheostomies without adverse effects.","PeriodicalId":19932,"journal":{"name":"Pediatric Pulmonology","volume":"61 9","pages":"e71835"},"PeriodicalIF":2.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13579341/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148977666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0