Pain Research & Management最新文献

{"title":"Investigation of the Relationship Between Type D Personality and Depression, Anxiety and Somatosensory Amplification in Patients With Fibromyalgia.","authors":"Meltem Hazel Şimşek, Ulaş Korkmaz, Fatma Gül Helvacı Çelik, Nurçe Çilesizoğlu Yavuz, Çiçek Hocaoğlu","doi":"10.1155/prm/5315083","DOIUrl":"10.1155/prm/5315083","url":null,"abstract":"<p><p><b>Objective:</b> This study aimed to investigate differences in depression, anxiety and somatosensory amplification between fibromyalgia (FM) patients with and without type D personality (TDP) and healthy controls and to examine the mediating role of somatosensory amplification in the relationship between TDP and FM severity. <b>Methods:</b> A total of 159 participants were included in the cross-sectional case-control study and divided into three groups: FM patients with TDP (<i>n</i> = 56, mean age = 45.93 ± 11.01), FM patients without TDP (<i>n</i> = 48, mean age = 49.17 ± 11.18) and healthy controls (<i>n</i> = 55, mean age = 46.1 ± 9.64). Participants were assessed with the Fibromyalgia Impact Questionnaire (FIQ; administered only to FM patients), TDP Scale, Beck Depression Inventory, Beck Anxiety Inventory and Somatosensory Amplification Scale. Mediation analysis was performed to determine the mediating role of somatosensory amplification. <b>Results:</b> FM patients with TDP had significantly higher levels of depression, anxiety and somatosensory amplification compared to both FM patients without TDP and healthy controls (<i>p</i> < 0.001). Correlation analyses showed strong positive associations between TDP and anxiety (<i>r</i> = 0.729, <i>p</i> < 0.001) and depression (<i>r</i> = 0.794, <i>p</i> < 0.001). Somatosensory amplification was found to have a significant mediating role in the relationship between TDP and FM severity (<i>b</i> = 0.084, 95% CI = 0.018-0.172, <i>p</i> < 0.05). <b>Conclusion:</b> These results highlight TDP as an important psychological risk factor associated with increased depression, anxiety, and somatosensory amplification in FM patients. The apparent mediating role of somatosensory amplification suggests that addressing this mechanism and psychological stress with targeted psychosocial interventions may improve the efficacy of FM treatment.</p>","PeriodicalId":19913,"journal":{"name":"Pain Research & Management","volume":"2025 ","pages":"5315083"},"PeriodicalIF":2.5,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12097857/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144128258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiation Synovectomy: An Enticing Treatment Option for Inflammatory Joint Pain.","authors":"Ashutosh Dash, Tapas Das","doi":"10.1155/prm/8887391","DOIUrl":"10.1155/prm/8887391","url":null,"abstract":"<p><p>Radiosynovectomy (RSV) represents an advanced therapeutic modality in nuclear medicine, designed to treat chronic inflammatory joint disorders that are unresponsive to conventional therapies. This targeted approach involves the intra-articular administration of radioactive microparticles containing a β^--emitting radionuclide, selectively eradicating the inflamed synovial membrane while preserving surrounding tissues. As a minimally invasive, nonsurgical procedure routinely performed in outpatient settings, RSV offers a compelling alternative to more invasive interventions. Over time, RSV has evolved significantly, transitioning from the empirical use of radiocolloids to the development of specialized agents tailored for different joint types. Advancements in this field continue to explore a variety of β^--emitting radionuclides with unique emission characteristics, integrated into novel microparticles to improve both specificity and therapeutic efficacy. The selection of an optimal radionuclide hinges on critical nuclear and chemical properties, ensuring effective binding to microparticles and delivering favorable clinical outcomes. This review examines the evolution of RSV in joint disorder management, detailing its mechanisms of action, key factors influencing radionuclide and microparticle selection, and the methodologies involved in their development and production. Additionally, it provides an overview of commonly used radionuclides and microparticles, evaluating their effectiveness within the ever-evolving landscape of RSV.</p>","PeriodicalId":19913,"journal":{"name":"Pain Research & Management","volume":"2025 ","pages":"8887391"},"PeriodicalIF":2.5,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12092159/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144111551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of a Multimodal Pain Therapy Concept Including Intensive Physiotherapy on the Perception of Pain and the Quality of Life of Patients With Chronic Back Pain: A Prospective Observational Multicenter Study Named \"RütmuS\".","authors":"Katharina Zaglauer, Andrea Kunsorg, Vanessa Jakob, Lara Görg, Arndt Oehlschlägel, Rainer Riedel, Ursula Marschall, Dieter Welsink, Horst Schuhmacher, Maria Wittmann","doi":"10.1155/prm/6693678","DOIUrl":"10.1155/prm/6693678","url":null,"abstract":"&lt;p&gt;&lt;p&gt;&lt;b&gt;Question and Outcome Measures:&lt;/b&gt; In this study, an intervention group (multimodal therapy for chronic back pain) and a control group (standard outpatient treatment) were compared with regard to the primary endpoint of pain (NRS) at rest and the secondary endpoints pain (NRS) during movement, general health status (Short Form 12 (SF-12)), health-related quality of life (EQ-5D-5L), pain disability index (PDI), Hospital Anxiety and Depression Scale-Germany (HADS-D), and Hannover Functional Ability Questionnaire for Measuring Back Pain-Related Disability (FFbH-R). &lt;b&gt;Design and Participants:&lt;/b&gt; The total patient cohort of this prospective observational multicenter study consisted of 477 patients who were initially enrolled in the study from January 2019 to September 2020. &lt;b&gt;Intervention:&lt;/b&gt; The intervention group received physiotherapy, pain therapy (pain-therapeutic, body-related, and patient-specific treatment), and control examinations from the responsible physician in a 6-month structured interdisciplinary program. The evaluation points used in the analysis are the baseline survey, 6 months and 12 months after the start of the study. &lt;b&gt;Results:&lt;/b&gt; A total of 477 patients (243 in the intervention group and 234 in the control group) were included in the analysis; 42 patients in the intervention group deviated from the eligibility criteria due to insufficient adherence to study participation. Nonetheless, they were included in the analysis in line with the ITT principle. The primary endpoint, pain at rest (NRS), showed greater reductions in the intervention group compared to the control group, with mean differences of -0.492 (95% CI: [-0.866, -0.118], &lt;i&gt;p&lt;/i&gt; = 0.010) at 6 months (EVA 3) and -0.463 (95% CI: [-0.837, -0.089], &lt;i&gt;p&lt;/i&gt; = 0.015) at 12 months (EVA 5), respectively. Regarding the secondary endpoints, pain during movement exhibited a significantly greater reduction in the intervention group compared to the control group (&lt;i&gt;p&lt;/i&gt; &lt; 0.001). Quality of life, measured via the EQ-5D-5L index, improved significantly more in the intervention group than in the control group, as did functional capacity (FFbH-R) and physical health (SF-12 KSK) (&lt;i&gt;p&lt;/i&gt; &lt; 0.001). In contrast, mental health (SF-12 PSK) declined significantly during the intervention (&lt;i&gt;p&lt;/i&gt; &lt; 0.001). Disability (PDI) exhibited a significantly greater reduction in the intervention group compared to the control group (&lt;i&gt;p&lt;/i&gt; &lt; 0.001), whereas anxiety and depression levels (HADS-D) showed only slight changes in both groups, with anxiety being significant at &lt;i&gt;p&lt;/i&gt; = 0.0164 and depression not significant at &lt;i&gt;p&lt;/i&gt; = 0.1093. These results underscore the intervention's effectiveness across multiple health dimensions, particularly pain reduction and quality of life. &lt;b&gt;Conclusion:&lt;/b&gt; Multimodal pain therapy over a 6-month period is an effective intervention to improve the perception of pain at rest and during movement while enhancing the subjective quality of life","PeriodicalId":19913,"journal":{"name":"Pain Research & Management","volume":"2025 ","pages":"6693678"},"PeriodicalIF":2.5,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12085246/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144094543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identifying Latent Profiles of Healthy Adults' Biopsychosocial Pain Concepts.","authors":"Catherina Lenhof, Laura Dukek, Linda Wickering, Lena Hitschler, Michael Schneider, Tanja Hechler","doi":"10.1155/prm/5706849","DOIUrl":"10.1155/prm/5706849","url":null,"abstract":"<p><p><b>Objectives:</b> To develop effective, individualized pain science education for people with chronic (primary) pain, underlying pain concepts, defined as the understanding of what pain is, what function it serves, and what processes are thought to underpin it, are essential. Pain concepts and misconcepts of chronic pain can influence its development and maintenance. This study explores whether profiles of healthy adults' biopsychosocial pain concepts can be identified using a newly developed tool, the <i>biopsychosocial pain concept matrix</i> (BiPS matrix), and if adults assigned to the profiles differ regarding sociodemographic and pain-related variables. <b>Methods:</b> <i>N</i> = 229 healthy adults (75% female, <i>M</i> = 22.66 years, SD = 3.61) participated in an online survey. The BiPS matrix assesses biopsychosocial pain concepts through 40 items on the biological, psychological, and social domains combined with the five content dimensions of the common-sense model of self-regulation. <b>Results:</b> A latent profile analysis (LPA) revealed a five-profile solution with distinct patterns of biopsychosocial pain concepts. Participants assigned to Profile 1 demonstrated strongly developed biopsychosocial pain concepts, Profile 2 showed weakly developed concepts, and Profiles 3 to 5 showed different levels of pain concepts. General and neurophysiological pain knowledge differed between profiles, with higher scores being associated with Profile 1 and lower scores with Profile 5. There were no differences in sociodemographic variables in adults assigned to the different profiles. <b>Discussion:</b> Results provide preliminary evidence for distinct profiles of biopsychosocial pain concepts among healthy adults. Further research should replicate these findings in clinical samples to better understand biopsychosocial pain concepts and their use for individualized pain science education.</p>","PeriodicalId":19913,"journal":{"name":"Pain Research & Management","volume":"2025 ","pages":"5706849"},"PeriodicalIF":2.5,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12084786/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144094548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Efficacy of Acupuncture Combined With Conventional Therapy for C5 Nerve Root Palsy After Posterior Cervical Decompression Surgery: A Randomized Controlled Study.","authors":"Hua Wei, Qingfeng Shen, Yuang Fu, Yubo Tan, Junwei Gao, Yingpeng Xia","doi":"10.1155/prm/2625552","DOIUrl":"https://doi.org/10.1155/prm/2625552","url":null,"abstract":"<p><p><b>Objectives:</b> To observe the clinical efficacy of Tiaokou acupoint-penetrating Chengshan combined with conventional therapy for C5 nerve root palsy after posterior cervical decompression surgery. <b>Methods:</b> A total of 52 patients undergoing posterior cervical decompression surgery at Tianjin Union Medical Center from March 2020 to March 2023 were grouped using computer-generated random numbers. Group A (<i>n</i> = 26) received the treatment of acupuncture combined with conventional therapy. Group B (<i>n</i> = 26) received only conventional therapy. <b>Results:</b> The VAS scores of the two groups after treatment were significantly lower than scores before treatment (<i>p</i> < 0.01). The JOA scores, Lovett muscle strength grade, and shoulder ROM of the two groups after treatment were significantly higher than those before treatment (<i>p</i> < 0.01). After treatment, the VAS scores of Group A were significantly lower than those in Group B (<i>p</i> < 0.01) while the JOA scores, Lovett muscle strength grade, and shoulder ROM were significantly higher than those in Group B (<i>p</i> < 0.01). There were significant differences in VAS difference (<i>p</i> < 0.01) and JOA difference (<i>p</i> < 0.01) after 2 weeks of intervention treatment in Group A compared to Group B. There was a significant difference in the improvement of shoulder ROM in Group A after 2 weeks of intervention compared to Group B. <b>Conclusions:</b> The acupuncture method of Tiaokou acupoint-penetrating Chengshan combined with conventional nutritional support therapy was more effective in patients with C5 nerve root palsy after posterior cervical decompression surgery compared to conventional nutritional support therapy. <b>Trial Registration:</b> Clinical Trial Registry identifier: ChiCTR2300073583.</p>","PeriodicalId":19913,"journal":{"name":"Pain Research & Management","volume":"2025 ","pages":"2625552"},"PeriodicalIF":2.5,"publicationDate":"2025-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12066177/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144038044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predicting Postcesarean Pain: A Prospective Cohort Study Using a 3-Question Questionnaire, Local Anesthesia Infiltration, and Observer Rating.","authors":"Unyime S Ituk, Sapna Ravindranath","doi":"10.1155/prm/6903333","DOIUrl":"https://doi.org/10.1155/prm/6903333","url":null,"abstract":"<p><p><b>Purpose:</b> Acute postoperative pain is a typical complaint following cesarean delivery (CD). The current standard for postcesarean pain management is the use of a multimodal analgesia regimen which is beneficial for many but may be inadequate for some patients. This study aimed to determine if combining patients' response to a pain rating questionnaire, their pain score during local anesthetic infiltration (LAI) preceding spinal anesthesia for CD, and an anesthesiologist's prediction of postcesarean pain severity can predict the intensity of postcesarean pain. <b>Methods:</b> This was a prospective study of ninety women undergoing scheduled CD under spinal anesthesia. Patients completed a pain rating questionnaire preoperatively and rated pain on LAI before spinal injection, and an anesthesiologist predicted the severity of postcesarean pain. Postoperative pain scores were assessed at rest and with movement at 6, 24, and 48 h after surgery. <b>Results:</b> The patient's expected postoperative pain (<i>β</i> = 0.39, <i>p</i>=0.0011), perceived analgesic requirements (<i>β</i> = 0.34, <i>p</i>=0.0002), pain on LAI (<i>β</i> = 0.22, <i>p</i>=0.004), and anesthesiologist's predicted postoperative pain severity (<i>β</i> = 0.22, <i>p</i>=0.01) were associated with mean postoperative pain after CD. The multivariate model analysis found that the pain rating questionnaire and the an anesthesiologist's prediction of postcesarean pain severity contributed to postoperative pain modeling (<i>R</i> ² = 0.27). <b>Conclusion:</b> Combining a preoperative pain rating questionnaire with an anesthesiologist's prediction of postcesarean pain severity accounted for 27% of the variance in mean postoperative pain with movement and may be a useful tool in predicting postcesarean pain. <b>Implications:</b> This study highlights the potential of a combined preoperative pain rating questionnaire and anesthesiologist's predictions to improve postcesarean pain management. By accounting for 27% of the variance in mean postcesarean pain with movement, this approach could enhance pain management outcomes for CD patients.</p>","PeriodicalId":19913,"journal":{"name":"Pain Research & Management","volume":"2025 ","pages":"6903333"},"PeriodicalIF":2.5,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12037255/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144037456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Do We Ask What the Deities Can Do for Us? The Roles of Dao Religion and Resilience in Suicidality in Chronic Pain.","authors":"Ling-Jun Liu, Hsiu-Ling Peng, Edward Meng-Hua Lin, Wan-Ping Liang","doi":"10.1155/prm/3056383","DOIUrl":"https://doi.org/10.1155/prm/3056383","url":null,"abstract":"<p><p><b>Objectives:</b> Resilience to pain is a protective factor against aversive pain outcomes, such as suicide. Religiosity as a cornerstone of resilience has been found to be associated with reduced risk of suicidality in chronic pain. However, affiliations to different religions have displayed differences in suicide risk. This study focuses on the roles of pain resilience and Dao religion in mitigating suicidal experience in individuals with chronic pain. <b>Methods:</b> This study adopted a mixed-method approach. A preliminary investigation was conducted regarding the internal consistency and construct validity of the translated version of the pain resilience scale (PRS). Qualitative data were collected through interviews with individuals experiencing chronic pain. Levels of PRS and gender were included in the logistic regression on the probability of suicide attempts. The role of Dao practice was qualitatively analyzed through narrative analysis. <b>Results:</b> Among the 24 participants, 14 were affiliated with the Dao religion; therefore, the transcripts of these 14 interviews were analyzed. Individuals with moderate scores on the PRS were 11.60 times less likely to have attempted suicide than those with low PRS scores. The likelihood further decreased by 38.7 times in those with high PRS scores. Four themes emerged from the qualitative interviews. The participants experienced a burden from pain, made efforts to please the deities in exchange for better pain control, continuously adjusted to pain, and ultimately developed a new perspective on the relationship between their religion and pain. Many individuals have engaged in Dao rituals to try to alleviate their physical and psychological pain. Most participants tended to offer a religious interpretation of enlightening moments after surviving a suicide attempt. <b>Discussion:</b> This study illustrates how pain resilience and Dao religious practices mitigate suicidality in chronic pain. <b>Trial Registration:</b> ClinicalTrials.gov identifier: NCT05148364.</p>","PeriodicalId":19913,"journal":{"name":"Pain Research & Management","volume":"2025 ","pages":"3056383"},"PeriodicalIF":2.5,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12021491/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144041987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Epidural Pulsed Radiofrequency Treatment in Persistent Spinal Pain Syndrome: A Prospective Clinical Study.","authors":"Burak Erken, Gunay Yolcu, Tuba Tanyel Saracoglu","doi":"10.1155/prm/6200102","DOIUrl":"https://doi.org/10.1155/prm/6200102","url":null,"abstract":"<p><p><b>Background:</b> Persistent spinal pain syndrome type-2 (PSPS-II) is a chronic condition that is characterized by severe pain and results in disability and a significant reduction in quality of life. Despite the wide range of interventional pain treatments that are applied, depending on the complexity of the etiology, epidural pulsed radiofrequency (EPRF) application has emerged as an approach that has gained popularity in recent years. <b>Objective:</b> The objective of this study is to examine the efficacy of EPRF in patients diagnosed with PSPS-II. <b>Methodology:</b> In this prospectively designed study, patients with PSPS-II who had not responded to conservative treatments and epidural steroid injections were subjected to fluoroscopy-guided EPRF. Patients were evaluated with the Numeric Rating Scale (NRS) for pain severity and the Douleur Neuropathique-4 (DN-4) questionnaire for presence of neuropathic pain before the procedure and at one and three months after. Although the change in NRS score was established as the primary outcome measure, the change in the number of patients with neuropathic pain according to the DN-4 was determined as the secondary outcome measure. <b>Result:</b> In the final analysis, data from 42 patients were evaluated. The analysis of the time-dependent change in NRS revealed a statistically significant reduction in the scores for the first and third months, in comparison with the initial measurement. A significant decrease was observed in the number of patients diagnosed with neuropathic pain according to the DN-4 questionnaire in the first month, in comparison with the baseline. However, no significant change was noted in the third month. <b>Conclusion:</b> The utilization of EPRF for the treatment of chronic radicular pain in the setting of PSPS-II appears to be effective in the short term. Further studies are required to ascertain its long-term effects. <b>Trial Registration:</b> ClinicalTrials.gov identifier: NCT06239857.</p>","PeriodicalId":19913,"journal":{"name":"Pain Research & Management","volume":"2025 ","pages":"6200102"},"PeriodicalIF":2.5,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12008484/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143973811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Experimental Pain and Visual Feedback on the Accuracy and Precision of Knee Joint Position Sense.","authors":"Shaojun Liao, Lars Arendt-Nielsen, Kelun Wang, Rogerio Pessoto Hirata","doi":"10.1155/prm/9328803","DOIUrl":"https://doi.org/10.1155/prm/9328803","url":null,"abstract":"<p><p><b>Objective:</b> To investigate the effects of experimental pain and visual feedback on the accuracy and precision of knee joint position sense following a period of motor training. <b>Methods:</b> Forty healthy young subjects (age: 24.5 ± 3.6 years old) underwent an 8 day motor training. After the training, they were instructed to perform a knee reposition task before and after receiving an injection of either hypertonic (pain group) or isotonic (control group) saline into the infrapatellar fat pad of the left knee. The Visual Analog Scale (VAS) was recorded for both groups. In each condition, participants were instructed to extend their knee to three predetermined target positions (30°, 45°, and 60°) for 10 repetitions, both with visual feedback (VF) and without visual feedback (NVF). The accuracy and precision of the knee reposition task were measured before and after the injection. Accuracy was determined by calculating the mean difference between the target angle and the actual angle achieved, while precision was determined by calculating the standard deviation of all actual angles. Data were analyzed using two-way ANOVAs and independent-samples <i>t</i>-tests to compare the pain and control groups. <b>Results:</b> The VAS were 4.14 ± 2.48 for the pain group and 0.83 ± 0.89 for the control group. There was a significant decrease in knee accuracy after the injection of hypertonic saline compared to movements before the injection during VF (<i>p</i>=0.009). The pain group showed significantly worse knee accuracy compared to the control group in the relative change of performance during VF (<i>p</i>=0.015). <b>Conclusions:</b> This study demonstrates that experimental knee pain impairs the accuracy of joint position sense, even after a period of motor training. This could serve as a helpful cue for individuals with knee pain to pursue timely treatment, thereby reducing the risk of additional injury. <b>Trial Registration:</b> ClinicalTrials.gov identifier: NCT04146311.</p>","PeriodicalId":19913,"journal":{"name":"Pain Research & Management","volume":"2025 ","pages":"9328803"},"PeriodicalIF":2.5,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12006686/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144037332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Chronic Postsurgical Pain Knowledge Among Surgical Nurses in a Turkish University Hospital.","authors":"Aysel Doğan, Runida Doğan, Dilek Güneş, Nazlıcan Bağci","doi":"10.1155/prm/9954969","DOIUrl":"https://doi.org/10.1155/prm/9954969","url":null,"abstract":"<p><p><b>Objective:</b> Chronic postsurgical pain (CPSP) is a significant yet often underrecognized complication following surgical procedures, impacting patients' quality of life. Surgical nurses play a crucial role in postoperative care and pain management, making their knowledge of CPSP essential for improving patient outcomes. The aim of the study was to assess CPSP knowledge among surgical nurses in a Turkish University Hospital. <b>Methods:</b> This descriptive cross-sectional study included a total of 175 nurses. Data were collected from nurses employed in the surgical units of İnönü University hospital between May 15 and June 15, 2023. Personal information and knowledge-level forms created by the researchers were used for data collection. IBM SPSS Statistics v.25 was used for the statistical analysis. <b>Results:</b> The mean CPSP knowledge score of the nurses working in surgical clinics was 9.26 ± 1.40 (min. = 0, max. = 12) and 75.4% of them had sufficient knowledge. Surgical nurses' knowledge level of CPSP was influenced by their education level (<i>p</i> ≤ 0.001) and total duration of employment in the surgical department (<i>p</i>=0.002). <b>Conclusions:</b> Although most surgical nurses had sufficient CPSP knowledge, gaps remained, particularly among those with lower education levels and less experience. Targeted training programs and continuous professional development initiatives are recommended to enhance CPSP awareness and improve postoperative pain management practices.</p>","PeriodicalId":19913,"journal":{"name":"Pain Research & Management","volume":"2025 ","pages":"9954969"},"PeriodicalIF":2.5,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11996284/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144047672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}