Pain Research & Management最新文献

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Evaluation of Patient Comfort and Impact of Different Anesthesia Techniques on the Temporomandibular Joint Arthrocentesis Applications by Comparing Gow-Gates Mandibular Block Anesthesia with Auriculotemporal Nerve Block. 通过比较Gow-Gates下颌骨阻滞麻醉与耳颞神经阻滞麻醉对患者舒适度及不同麻醉技术对颞下颌关节穿刺应用的影响。
IF 2.9 3区 医学
Pain Research & Management Pub Date : 2022-08-31 eCollection Date: 2022-01-01 DOI: 10.1155/2022/4206275
Onur Atalı, Elif Özçelik, Onur Gönül, Hasan Garip
{"title":"Evaluation of Patient Comfort and Impact of Different Anesthesia Techniques on the Temporomandibular Joint Arthrocentesis Applications by Comparing Gow-Gates Mandibular Block Anesthesia with Auriculotemporal Nerve Block.","authors":"Onur Atalı,&nbsp;Elif Özçelik,&nbsp;Onur Gönül,&nbsp;Hasan Garip","doi":"10.1155/2022/4206275","DOIUrl":"https://doi.org/10.1155/2022/4206275","url":null,"abstract":"<p><strong>Aim: </strong>Temporomandibular disorders (TMDs) are clinical situations that are characterized by pain, sound, and irregular movements of the temporomandibular joints. The most common method in the treatment of TMDs is arthrocentesis. This study aims to compare the effect of conventional extraoral auriculotemporal nerve block (ANB) and Gow-Gates (GG) mandibular anesthesia techniques on patient comfort in an arthrocentesis procedure.</p><p><strong>Materials and methods: </strong>We performed this study on 40 patients who underwent TMJ arthrocentesis with ANB (<i>n</i> = 20) or GG (<i>n</i> = 20) mandibular anesthesia techniques at the Marmara University Faculty of Dentistry between 2016 and 2019. The predictor variable was the type of an anesthesia technique, and the outcome variables included were pain, maximum mouth opening (MMO), and protrusive movement (PM). They were compared at the preoperative period and 3<sup>rd</sup> and 6<sup>th</sup> month periods. Statistical analysis included means with standard deviations, a one-way ANOVA for continuous data, and the results were evaluated at the significance level of <i>p</i> < 0.05.</p><p><strong>Results: </strong>No statistically significant difference was observed between the VAS values, MMO, and PM averages of preoperative, 3<sup>rd</sup> and 6<sup>th</sup> months of ANB and GG (<i>p</i>=0.142, <i>p</i>=0.209, and <i>p</i>=0.148).</p><p><strong>Conclusion: </strong>Both anesthesia techniques have provided effective results in terms of pain and functional jaw movements in the postoperative period in arthrocentesis treatment.</p>","PeriodicalId":19913,"journal":{"name":"Pain Research & Management","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2022-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9453085/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33459430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pain Sensitization and Neuropathic Pain-like Symptoms Associated with Effectiveness of Exercise Therapy in Patients with Hip and Knee Osteoarthritis. 髋关节和膝关节骨关节炎患者运动治疗效果与疼痛致敏和神经性疼痛样症状相关
IF 2.9 3区 医学
Pain Research & Management Pub Date : 2022-08-29 eCollection Date: 2022-01-01 DOI: 10.1155/2022/4323045
Takafumi Hattori, Kazuhiro Shimo, Yuto Niwa, Yuichi Katsura, Yuji Tokiwa, Satoshi Ohga, Takako Matsubara
{"title":"Pain Sensitization and Neuropathic Pain-like Symptoms Associated with Effectiveness of Exercise Therapy in Patients with Hip and Knee Osteoarthritis.","authors":"Takafumi Hattori,&nbsp;Kazuhiro Shimo,&nbsp;Yuto Niwa,&nbsp;Yuichi Katsura,&nbsp;Yuji Tokiwa,&nbsp;Satoshi Ohga,&nbsp;Takako Matsubara","doi":"10.1155/2022/4323045","DOIUrl":"https://doi.org/10.1155/2022/4323045","url":null,"abstract":"<p><p>Pain sensitization and neuropathic pain-like symptoms are some of the common pain symptoms in patients with lower limbs, including hip and knee, osteoarthritis (HOA/KOA). Exercise therapy has been the first-line treatment; however, the effects differ for each patient. This prospective cohort study investigated the relationship between the effectiveness of exercise therapy and pretreatment characteristics (radiologic severity, pain sensitization, and neuropathic pain-like symptoms) of patients with HOA/KOA. We assessed the pain intensity using a numerical rating scale (NRS) before and after 12 weeks of exercise therapy in patients with HOA/KOA (<i>n</i> = 101). Before treatment, the Kellgren-Lawrence (K-L) grade; minimum joint space width (mJSW); pressure pain threshold (PPT) and temporal summation of pain (TSP) at the affected joint, tibia, and forearm; Central Sensitization Inventory-9; and painDETECT questionnaire (PDQ) were assessed. Cluster analysis was based on the pretreatment NRS and change in NRS with exercise therapy to identify the subgroups of pain reduction. The pretreatment characteristics of each cluster were compared. According to the results of the cluster analyses, patients in cluster 1 had severe pain that did not improve after exercise therapy, patients in cluster 2 had severe pain that improved, and those in cluster 3 had mild pain that improved. The patients in cluster 1 exhibited lower PPT at all measurement sites, higher TSP at the affected joint, and higher PDQ scores than those in other clusters. There was no difference in the K-L grade and mJSW among the clusters. The subgroup with severe pain and pain sensitization or neuropathic pain-like symptoms at pretreatment, even with mild joint deformity, may have difficulty in achieving improvement in pain after 12 weeks of exercise therapy. These findings could be useful for prognosis prediction and for planning exercise therapy and combining with other treatment.</p>","PeriodicalId":19913,"journal":{"name":"Pain Research & Management","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2022-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9444422/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33448061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Improvement in Disability Mediates the Effect of Self-Efficacy on Pain Relief in Chronic Low Back Pain Patients with Exercise Therapy. 运动治疗慢性腰痛患者自我效能感在残疾改善中的调节作用
IF 2.9 3区 医学
Pain Research & Management Pub Date : 2022-08-29 eCollection Date: 2022-01-01 DOI: 10.1155/2022/4203138
Yuta Shinohara, Kenta Wakaizumi, Aiko Ishikawa, Mari Ito, Reiko Hoshino, Chisato Tanaka, Saki Takaoka, Michiyuki Kawakami, Osahiko Tsuji, Daisuke Fujisawa, Toshiyuki Fujiwara, Tetsuya Tsuji, Hiroshi Morisaki, Shizuko Kosugi
{"title":"Improvement in Disability Mediates the Effect of Self-Efficacy on Pain Relief in Chronic Low Back Pain Patients with Exercise Therapy.","authors":"Yuta Shinohara,&nbsp;Kenta Wakaizumi,&nbsp;Aiko Ishikawa,&nbsp;Mari Ito,&nbsp;Reiko Hoshino,&nbsp;Chisato Tanaka,&nbsp;Saki Takaoka,&nbsp;Michiyuki Kawakami,&nbsp;Osahiko Tsuji,&nbsp;Daisuke Fujisawa,&nbsp;Toshiyuki Fujiwara,&nbsp;Tetsuya Tsuji,&nbsp;Hiroshi Morisaki,&nbsp;Shizuko Kosugi","doi":"10.1155/2022/4203138","DOIUrl":"https://doi.org/10.1155/2022/4203138","url":null,"abstract":"<p><strong>Background: </strong>The biopsychosocial mechanism by which exercise leads to improvement in chronic low back pain (CLBP) remains unstudied. This prospective cohort study was performed to examine the effectiveness of exercise on pain, disability, and psychological status for CLBP. We also tested path analytic models in which changes in these variables were included.</p><p><strong>Methods: </strong>CLBP patients who visited the Interdisciplinary Pain Center of Keio University Hospital from July 2018 to April 2020 were included. The propensity score matching was performed between patients who underwent exercise (the exercise group) and those who did not (the control group). At the first visit and at the 3-month follow-up, pain (Numerical Rating Scale (NRS)), disability (Pain Disability Assessment Scale (PDAS)), and psychological status (Pain Self-Efficacy Questionnaire (PSEQ), and Pain Catastrophizing Scale (PCS)) were assessed. Changes in pain and disability at the follow-up were compared between the groups. The relationships between changes in pain, disability, and psychological variables were examined using Pearson's correlation and mediation analysis.</p><p><strong>Results: </strong>A significantly larger decrease in the PDAS was observed in the exercise group (<i>N</i> = 49) than in the control (<i>N</i> = 49) (<i>p</i> < 0.05). Increased PSEQ scores were significantly correlated with decreased NRS scores in both groups. In the exercise group, decreased PDAS fully mediated the relationship between increased PSEQ and decreased NRS (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>Exercise improved disability, and the improved disability by exercise mediated the effect of increased self-efficacy on pain relief in CLBP patients.</p>","PeriodicalId":19913,"journal":{"name":"Pain Research & Management","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2022-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9444439/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33448063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Far-Contralateral Oblique (FCO) Sacroiliac Joint Injection: Description of a Novel Technique. 远对侧斜骶髂关节注射:一种新技术的描述。
IF 2.9 3区 医学
Pain Research & Management Pub Date : 2022-08-22 eCollection Date: 2022-01-01 DOI: 10.1155/2022/3312589
David W Lee, Patrick Buchanan, Shashank Vodapally, Christopher James, Jack Diep
{"title":"Far-Contralateral Oblique (FCO) Sacroiliac Joint Injection: Description of a Novel Technique.","authors":"David W Lee,&nbsp;Patrick Buchanan,&nbsp;Shashank Vodapally,&nbsp;Christopher James,&nbsp;Jack Diep","doi":"10.1155/2022/3312589","DOIUrl":"https://doi.org/10.1155/2022/3312589","url":null,"abstract":"<p><p>Sacroiliac (SI) joint arthropathy is the primary pain generator in approximately 15-25% of patients with axial low back pain and traditionally diagnosed with >50% pain reduction following an intra-articular injection localized to the inferior 1/3 of the SI joint. The conventional technique for accessing the SI joint encompasses a posterior approach with fluoroscopic guidance at 10-20⁰ contralateral oblique angulation, and minor adjustments to this approach have been implemented with varying degrees of success. The authors present a novel technique for SI joint injection, infiltrating the middle third of the joint through an alternative far-contralateral oblique (FCO) approach, angulation between 20-40⁰. This approach theoretically endows easier access to the SI joint and at the very least provides another option for interventionalists in the diagnosis and treatment of sacroiliac joint pain. It can also be utilized to determine if a patient is a candidate for posterior percutaneous SI joint fusion. The authors sought to document this approach to ensure that it was both reproducible and safe, while recognizing the need for future studies.</p>","PeriodicalId":19913,"journal":{"name":"Pain Research & Management","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2022-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9423991/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40334460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Axial Length of the Eyeball and Bioelectrical Activity of Masticatory and Neck Muscles: A Preliminary Report. 眼球轴向长度与咀嚼肌和颈部肌的生物电活动:初步报告。
IF 2.9 3区 医学
Pain Research & Management Pub Date : 2022-08-16 eCollection Date: 2022-01-01 DOI: 10.1155/2022/6115782
Grzegorz Zieliński, Michał Baszczowski, Maria Rapa, Anna Matysik-Woźniak, Magdalena Zawadka, Jacek Szkutnik, Piotr Gawda, Robert Rejdak, Piotr Majcher, Michał Ginszt
{"title":"The Axial Length of the Eyeball and Bioelectrical Activity of Masticatory and Neck Muscles: A Preliminary Report.","authors":"Grzegorz Zieliński,&nbsp;Michał Baszczowski,&nbsp;Maria Rapa,&nbsp;Anna Matysik-Woźniak,&nbsp;Magdalena Zawadka,&nbsp;Jacek Szkutnik,&nbsp;Piotr Gawda,&nbsp;Robert Rejdak,&nbsp;Piotr Majcher,&nbsp;Michał Ginszt","doi":"10.1155/2022/6115782","DOIUrl":"https://doi.org/10.1155/2022/6115782","url":null,"abstract":"<p><strong>Objective: </strong>The present study aimed to evaluate the correlation of eye length and bioelectric activity of temporalis, masseter, digastric, and sternocleidomastoid muscles in women with myopia compared to healthy women.</p><p><strong>Methods: </strong>Based on the exclusion and inclusion criteria, 42 women aged 24 years (±2 years) were eligible for the study. Two equally sized groups with myopic (<i>n</i> = 21) and emmetropic healthy subjects (<i>n</i> = 21) were formed. An electromyographic study of the examined muscles was performed in four conditions: at rest, during maximal voluntary clenching in the intercuspal position, during maximal voluntary clenching on dental cotton rollers, and during maximal mouth opening using BioEMG III (BioResearch Associates, Inc. Milwaukee, WI, USA). The IOL Master 500 (Carl Zeiss Meditec, Jena, Germany) was used to examine the eyeball length. Statistical analysis showed significant positive correlations during mouth opening in both groups with open and closed eyes.</p><p><strong>Results: </strong>A greater number of correlations between the analyzed variables was observed in emmetropic women. In almost all cases, the longer axial eye length was associated with an increase in the bioelectrical activity of the analyzed muscles. Significant correlations were most often observed within the masseter and digastric muscles during the maximum mouth opening and at rest.</p><p><strong>Conclusion: </strong>There is a relationship between the bioelectrical activity of the masticatory muscles and the axial length of the eyeball on the same side.</p>","PeriodicalId":19913,"journal":{"name":"Pain Research & Management","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2022-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9398725/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33438534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Surgical Reduction and Direct Repair Using Pedicle Screw-Rod-Hook Fixation in Adult Patients with Low-Grade Isthmic Spondylolisthesis. 成人轻度峡部滑脱患者椎弓根螺钉-杆-钩固定手术复位和直接修复。
IF 2.9 3区 医学
Pain Research & Management Pub Date : 2022-08-10 eCollection Date: 2022-01-01 DOI: 10.1155/2022/8410519
Yongjian Gao, Chen Zhao, Lei Luo, Liehua Liu, Lichuan Liang, Dianming Jiang, Pei Li, Qiang Zhou
{"title":"Surgical Reduction and Direct Repair Using Pedicle Screw-Rod-Hook Fixation in Adult Patients with Low-Grade Isthmic Spondylolisthesis.","authors":"Yongjian Gao,&nbsp;Chen Zhao,&nbsp;Lei Luo,&nbsp;Liehua Liu,&nbsp;Lichuan Liang,&nbsp;Dianming Jiang,&nbsp;Pei Li,&nbsp;Qiang Zhou","doi":"10.1155/2022/8410519","DOIUrl":"https://doi.org/10.1155/2022/8410519","url":null,"abstract":"<p><strong>Background: </strong>Although direct pars repair using a pedicle screw-rod-hook system has achieved satisfactory results in patients with spondylolysis, its application in adults with low-grade isthmic spondylolisthesis is rarely reported.</p><p><strong>Objective: </strong>To assess the surgical effect of reduction and direct repair surgery with a pedicle screw-rod-hook system combined with autogenous bone grafts in adult patients with low-grade isthmic spondylolisthesis.</p><p><strong>Methods: </strong>Sixty-four adult patients with low-grade isthmic spondylolisthesis underwent reduction and direct repair using a pedicle screw-rod-hook system in our department from September 2009 to April 2018. The clinical efficacy was evaluated by clinical and radiological assessments.</p><p><strong>Results: </strong>The average follow-up was 52.15 ± 9.96 months. The visual analog scale (VAS) scores (VAS-lumbar and VAS-leg) and Oswestry Disability Index (ODI) at the final follow-up (FFU) were significantly lower than the preoperative levels (<i>P</i> < 0.05). The modified Prolo score was \"excellent\" for 60 patients (93.75%) and \"good\" for 4 patients (6.25%). The slip distance and slipping percentage showed significant decreases postoperatively and FFU compared to preoperatively (<i>P</i> < 0.05). There were no significant differences in the disc height, slip angle, and range of motion of the surgical intervertebral space or upper intervertebral space between preoperation and FFU (<i>P</i> < 0.05). Successful bony fusion had a 96.86% success rate.</p><p><strong>Conclusion: </strong>Reduction of slip and direct repair using pedicle screw-rod-hook fixation combined with autogenous iliac bone grafting in adult patients with low-grade isthmic spondylolisthesis is a safe and effective technique.</p>","PeriodicalId":19913,"journal":{"name":"Pain Research & Management","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2022-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385336/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40432128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Methylprednisolone as an Adjunct to Local Infiltration on Laminoplasty or Laminectomy before Wound Closure: A Randomized Controlled Trial. 甲基强的松龙在伤口闭合前椎板成形术或椎板切除术中辅助局部浸润:一项随机对照试验。
IF 2.9 3区 医学
Pain Research & Management Pub Date : 2022-08-03 eCollection Date: 2022-01-01 DOI: 10.1155/2022/2274934
Niti Shrestha, Bo Han, Xiying Wang, Wenqing Jia, Fang Luo
{"title":"Methylprednisolone as an Adjunct to Local Infiltration on Laminoplasty or Laminectomy before Wound Closure: A Randomized Controlled Trial.","authors":"Niti Shrestha,&nbsp;Bo Han,&nbsp;Xiying Wang,&nbsp;Wenqing Jia,&nbsp;Fang Luo","doi":"10.1155/2022/2274934","DOIUrl":"https://doi.org/10.1155/2022/2274934","url":null,"abstract":"<p><p><i>TrialDesign</i>. Patients undergoing laminoplasty and laminectomy often experience severe postoperative pain. Local infiltration analgesia during spine surgery significantly reduces postoperative pain, which only upholds for a short time. Whether methylprednisolone and local anaesthetics are better than local anaesthetics alone in postoperative analgesia is yet to be determined. The primary aim of this research was the postoperative evaluation of efficacy and safety of methylprednisolone when used as an adjunct to local anaesthesia, ropivacaine, before wound closure after surgical procedures, laminoplasty or laminectomy. <i>Methods</i>. 132 patients were divided with a ratio of 1 : 1 into methylprednisolone-ropivacaine and ropivacaine alone groups. Every 30 ml of local infiltration solution consisted of 15 ml of 1% ropivacaine with 14 ml of saline along with 1 ml of 40 mg methylprednisolone and 15 ml of 1% ropivacaine with 15 ml of saline in methylprednisolone-ropivacaine group and ropivacaine group, respectively. The standardization of the study solution depended on the number of levels involved in surgery. Primary outcome was the 48-hour cumulative sufentanil demand. <i>Results</i>. Demographic characters and surgical variables among the groups were identical. The average 48-hour cumulative sufentanil demand was 32.5 ± 20.6 <i>μ</i>g in the methylprednisolone-ropivacaine group and 50.9 ± 27.2 <i>μ</i>g in the ropivacaine group (<i>p</i> < 0.001). The estimated median time of demand of the first analgesia via patient-controlled analgesia (PCA) pump was 2.5 hours and 2 hours in the methylprednisolone-ropivacaine group and the ropivacaine group, respectively (hazard ratio (HR) was 0.53, with 95% Cl 0.33 to 0.87 and Log-rank of <i>p</i> = 0.0019). <i>Conclusion</i>. The infiltration of methylprednisolone as adjunct ropivacaine before wound closure is a safe and efficient strategy for pain management following laminoplasty or laminectomy.</p>","PeriodicalId":19913,"journal":{"name":"Pain Research & Management","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2022-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366200/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40696927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Pretreatment with Low-Dose Esketamine for Reduction of Propofol Injection Pain: A Randomized Controlled Trial. 低剂量艾氯胺酮预处理减少异丙酚注射疼痛:一项随机对照试验。
IF 2.9 3区 医学
Pain Research & Management Pub Date : 2022-08-02 eCollection Date: 2022-01-01 DOI: 10.1155/2022/4289905
Danyun Fu, Dingding Wang, Wenxian Li, Yuan Han, Jie Jia
{"title":"Pretreatment with Low-Dose Esketamine for Reduction of Propofol Injection Pain: A Randomized Controlled Trial.","authors":"Danyun Fu,&nbsp;Dingding Wang,&nbsp;Wenxian Li,&nbsp;Yuan Han,&nbsp;Jie Jia","doi":"10.1155/2022/4289905","DOIUrl":"https://doi.org/10.1155/2022/4289905","url":null,"abstract":"<p><strong>Background: </strong>Propofol-induced injection pain is a common adverse effect during the induction of general anesthesia. The purpose of this study is to investigate the effect of low-dose esketamine in preventing propofol injection pain.</p><p><strong>Methods: </strong>In this double-blind, randomized, controlled trial, patients scheduled for elective ear surgery under general anesthesia received either normal saline (NS), or 40 mg lidocaine, or 0.15 mg/kg esketamine 30 seconds before manual injection of propofol. The primary outcome of this study was the incidence of propofol injection pain. The secondary outcomes included injection pain score, vital signs, total dosage of vasoactive drugs used within 5 minutes after induction, and adverse events related to drugs.</p><p><strong>Results: </strong>A total of 105 patients were included. Compared with the NS group (67%), pretreatment with esketamine and lidocaine significantly reduced the incidence of injection pain to 29% and 33%, respectively (both <i>P</i> < 0.05); however, no significant difference was found between the esketamine and lidocaine groups. The median of injection pain score was significantly lower in the esketamine and lidocaine groups (both median (interquartile range) = 0 (0-1)) than that in the NS group (1 (0-2); <i>P</i> < 0.05). In addition, compared with the NS and lidocaine groups, preinjection esketamine provided more stable hemodynamic parameters within 5 minutes after induction (<i>P</i> < 0.05). No statistical difference was found in adverse events among the three groups.</p><p><strong>Conclusions: </strong>Pretreatment with a low-dose esketamine can not only reduce the incidence of propofol injection pain but also provide a more stable circulation in patients after anesthesia induction. This convenient, well-tolerated, and economic treatment appears as an option to be routinely applied in clinic practice. <i>Clinical Trial Registration.</i> This trial is registered with https://www.chictr.org.cn/showproj.aspx?proj=136690 (the number for the trial registration isChiCTR2100052742).</p>","PeriodicalId":19913,"journal":{"name":"Pain Research & Management","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2022-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363235/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40608245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Ultrasound-Guided Dry Needling for Trigger Point Inactivation in the Treatment of Postherpetic Neuralgia Mixed with Myofascial Pain Syndrome: A Prospective and Controlled Clinical Study. 超声引导干针灭穴法治疗带状疱疹后神经痛合并肌筋膜痛综合征的前瞻性对照临床研究。
IF 2.9 3区 医学
Pain Research & Management Pub Date : 2022-08-02 eCollection Date: 2022-01-01 DOI: 10.1155/2022/2984942
Yifa Huang, Mintai Gao, Qiaomin Li, Xuzheng Zhang, Huizhen Chen, Xinglu Li, Ping Hu, Qingshi Zeng
{"title":"Ultrasound-Guided Dry Needling for Trigger Point Inactivation in the Treatment of Postherpetic Neuralgia Mixed with Myofascial Pain Syndrome: A Prospective and Controlled Clinical Study.","authors":"Yifa Huang,&nbsp;Mintai Gao,&nbsp;Qiaomin Li,&nbsp;Xuzheng Zhang,&nbsp;Huizhen Chen,&nbsp;Xinglu Li,&nbsp;Ping Hu,&nbsp;Qingshi Zeng","doi":"10.1155/2022/2984942","DOIUrl":"https://doi.org/10.1155/2022/2984942","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the safety and effectiveness of ultrasound-guided dry needling for trigger point inactivation in the treatment of postherpetic neuralgia (PHN) mixed with myofascial pain syndrome (MPS).</p><p><strong>Methods: </strong>A prospective and controlled clinical study was conducted. From January 2020 to December 2020, among the 100 patients who received PHN treatment in the pain department, 54 patients complicated with MPS were randomly divided into the dry needling group D (<i>n</i> = 28) and pharmacotherapeutic group P (<i>n</i> = 26). Visual analogue score (VAS) and McGill Pain Questionnaire (MPQ) were taken as primary indicators. Ultrasound-guided inactivation of myofascial trigger points (MTrPs) with dry needling and intradermal needling combined with press needling were applied on group D and pharmacotherapeutic only treatment on group P respectively. The VAS score <3 and/or the MPQ score <2 represents effective treatment. The VAS score >3 and/or the MPQ score >2 represents recurrent in follow-up study three months after the treatment.</p><p><strong>Results: </strong>After four weeks treatment, the effective rate of one month later of the group D was 92.9% and the effective rate of group P was 38.5%, respectively. The recurrent rate of group D was 7.1% and 34.6% for group P, respectively, for follow-up three months later. The satisfactory rate of group D was higher than that of group P.</p><p><strong>Conclusion: </strong>Ultrasound-guided dry needling and intradermal needling combined with press needling were more effective than only pharmacotherapeutic treatment for PHN mixed with MPS, with lower recurrent rate and higher patient's satisfactory rate.</p>","PeriodicalId":19913,"journal":{"name":"Pain Research & Management","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2022-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363202/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40605739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neuropathic Pain Relief after Surgical Neurolysis in Patients with Traumatic Brachial Plexus Injuries: A Preliminary Report. 外伤性臂丛神经损伤手术神经松解术后神经性疼痛的缓解:初步报告。
IF 2.9 3区 医学
Pain Research & Management Pub Date : 2022-08-02 eCollection Date: 2022-01-01 DOI: 10.1155/2022/5660462
Armando Armas-Salazar, Noe Téllez-León, Ana Isabel García-Jerónimo, Francisco Alberto Villegas-López, José Luis Navarro-Olvera, José Damián Carrillo-Ruiz
{"title":"Neuropathic Pain Relief after Surgical Neurolysis in Patients with Traumatic Brachial Plexus Injuries: A Preliminary Report.","authors":"Armando Armas-Salazar,&nbsp;Noe Téllez-León,&nbsp;Ana Isabel García-Jerónimo,&nbsp;Francisco Alberto Villegas-López,&nbsp;José Luis Navarro-Olvera,&nbsp;José Damián Carrillo-Ruiz","doi":"10.1155/2022/5660462","DOIUrl":"https://doi.org/10.1155/2022/5660462","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the usefulness of surgical neurolysis for neuropathic pain relief in patients with posttraumatic brachial plexus injury (BPI).</p><p><strong>Methods: </strong>A prospective, longitudinal, nonrandomized, self-controlled before and after study was performed to evaluate the pain changes according to their intensity using the Visual Analogue Scale (VAS), and the sensory recovery after surgery using the British Medical Research Council (BMRC) scale for sensory recovery. To establish significant changes, a paired <i>T</i>-test was performed, and in order to determine the magnitude of these changes, an effect size was measured. <i>α</i> = 0.05.</p><p><strong>Results: </strong>Ten patients were included with an average follow-up of 61.9 ± 53.62 months. The main mechanism of injury was vehicular trauma (70%). A significant decrease in pain after the surgical intervention was observed resulting from an average preoperative state according to VAS of 8.4 ± 1.58, to a postoperative state of 3.4 ± 3.27 (59.52%, <i>p</i> = 0.005, Δ = 1.572), added to a mean sensory improvement (25%) from 2.8 ± 1.62 to 3.5 ± 0.97 after surgery according to BMRC, without statistically significant changes (<i>p</i>=0.062), showing a moderate effect size (Δ = 0.413). Almost all patients showed improvement in the continuous and paroxysmal pattern of pain. No postoperative complications were observed. <i>Discussion</i>. These results suggest that in cases of BPI that originates from a compressive syndrome secondary to the posttraumatic fibrosis that surrounds the nerve structures causing strangulation and inducing hypernociception, the use of surgical neurolysis is an appropriate alternative for patients with medically refractory neuropathic pain.</p>","PeriodicalId":19913,"journal":{"name":"Pain Research & Management","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2022-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363225/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40605738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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