{"title":"TO STUDY THE ETIOLOGICAL PROFILE OF SHORT STATURE AMONG CHILDREN ATTENDING TERTIARY CARE CENTRE","authors":"Thilagavathi Duraisamy, Gem Raghav Prashanth R, Karnam Ravikumar","doi":"10.36106/paripex/0603590","DOIUrl":"https://doi.org/10.36106/paripex/0603590","url":null,"abstract":"Background Early detection and diagnosis of short stature decrease the effect of any underlying health condition and\u0000optimizes final adult height.This study was done identify the etiological profile of short stature.Methodology This was a\u0000prospective observational study conducted in children aged 2 to 18 years with short stature. Children who fail to\u0000complete the etiological work up and those who are not fitting in definition for short stature were excluded. Results 80\u0000children were included .44 were females and 36 were males. Endocrinological cause was the commonest, 53%(N=42)\u0000among which Growth hormone deficiency was predominant (20%).24 children(30%) had non endocrine causes among\u0000which syndromic causes were predominant(N=9).14 children had non pathological causes and familial short\u0000stature(N=8) was predominant in them Conclusion Pathological short stature was predominat among which endocrine\u0000causes were the commonest. Isolated Growth Hormone deficiency was the most common endocrine cause followed by\u0000hypopituitarism and hypothyroidism. There was statistically significant relationship between the presence of\u0000dysmorphism (p< .01) and parental consanguinity (p < .05) separately with the etiology. Majority (40%)were aged\u0000between 11-18 years denoting fairly late referral for short stature . So general paediatricians could be made aware of\u0000routine growth monitoring in children & early referral to a tertiary centre.","PeriodicalId":19910,"journal":{"name":"Paripex Indian Journal Of Research","volume":"88 1-2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140507933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"THE RANK AND RANKL NEXUS – MOLECULAR ASPECTS","authors":"Javeria Khan, Devaratnamma Mv, Asma Naaz, Pooja Deshkar, Sahiti Soni, Sumanya Bandi","doi":"10.36106/paripex/3703970","DOIUrl":"https://doi.org/10.36106/paripex/3703970","url":null,"abstract":"RANKL are the chemical mediators secreted by the resident cells of the connective tissue and in the mileau of periodontium\u0000they are released during the process of bone turnover either for bone remodelling during orthodontic tooth movement,\u0000normal masticatory force bearing, age related changes or for bone resorption due to pathological reasons where plaque\u0000influences the cells of inflammation to release PGE2, IL-1 and TNF alpha. These RANKL act on the circulating pre osteoclasts\u0000or monocyte macrophage cells which under the influence of M-CSF will start to colacase to form multinucleated osteoclasts\u0000that will resorb the bone. Thus, for these various changes to occur in the macrophages and preosteoclasts there will be a\u0000need of transcription factors like NFK, NFATc1, cFos and others. To understand intracellular mechanisms when RANKL\u0000binds onto the trimeric receptor RANK which leads to a better understanding of therapeutic management to deal with\u0000pathological bone destructive disease, so we have consolidated this narrative review.","PeriodicalId":19910,"journal":{"name":"Paripex Indian Journal Of Research","volume":"42 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140508075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A UNIQUE CASE OF MAXILLARY RHINOSPORIDIOSIS","authors":"Digvijay Singh","doi":"10.36106/paripex/1400945","DOIUrl":"https://doi.org/10.36106/paripex/1400945","url":null,"abstract":"Rhinosporidiosis is a chronic granulomatous disease of nasal cavity. It is prevalent in few parts of India. Here we present a\u0000case which involved the maxillary sinus with its extension to choana and nasopharynx. Mass removed by lateral\u0000rhinotomy approach. Very few articles published on involvement of maxilla and different surgical approaches were\u0000mentioned for its removal.","PeriodicalId":19910,"journal":{"name":"Paripex Indian Journal Of Research","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140508503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"RELEVANCE OF INTERNATIONAL SOLAR ALLIANCE (ISA) AND ITS CHALLANGES","authors":"Md. Asaad Raza","doi":"10.36106/paripex/5202875","DOIUrl":"https://doi.org/10.36106/paripex/5202875","url":null,"abstract":"In the development of cost-effective and transformational solar energy solutions,International Solar Alliance (ISA) is the\u0000action-oriented and mobilized efforts among various countries.ISA is a member-driven and collaborative platform and\u0000there are more than 120 countries working under ISA Framework Agreement.India is one of the leading country and has\u0000been reelected for ISA. The activity of the ISA is based on the four priory such as Analytics & Advocacy, Capacity\u0000Building, Programmatic Support and Readiness & enabling activities.The governance structure of the ISA is followed by\u0000ISA Assembly as an apex decision-making body, Steering Committee for strategic guidance, Secretariat as\u0000administrative arm and Head of ISA headed by the Director General.Due to immense demand to create and implement\u0000solar energy, ISA is initiated with One Sun, One World, One Grid (OSOWOG) programme. Now a days, ISA has various\u0000challenges like funding, policy coordination, limited participation and implementation. In this regards India has\u0000launched the scheme named as Indian Technical and Economic Cooperation (ITEC). For its proper implementation to\u0000get fruitful results on the ground,the administration will play vital role.","PeriodicalId":19910,"journal":{"name":"Paripex Indian Journal Of Research","volume":"11 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140508596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"EFFECTS OF THREE DIFFERENT TRAINING PROGRAMMES ON ABDOMINAL ADIPOSITY OF OVERWEIGHT COLLEGE GIRLS","authors":"D. Biswas","doi":"10.36106/paripex/0902606","DOIUrl":"https://doi.org/10.36106/paripex/0902606","url":null,"abstract":"The World Health Organization (WHO) describes overweight as one of the today's most important public health\u0000problems, which is escalating as a global epidemic. The purpose of the present study was an endeavor to the best\u0000method of handling overweight.Out of 96 selected participants from fluvio coastal zone of west Bengal,India on the basis\u0000of BMI,80 overweight girls (average age:20) were consider for the study.The subjects were divided into four groups (20\u0000for each group) randomly namely Weight Training Group (WTG), Aerobic Training Group (ATG), Graded Circuit\u0000Training Group (GCTG) and Control Group (CG).Separately designed 12 weeks training programme for WTG,ATG and\u0000GCTG was applied on the subjects at morning between 8.00 am to 9.15am for three alternative days per week. After\u0000every four weeks,total load was increased.Pre and post test on the groups were conducted to measure the training effect\u0000on Abdominal Adiposity of the subjects. The collected data were statistically analyzed by using the analysis of Covariance (p<0.05) to determine differences, the LSD test was applied as a post hoc test to find out the paired mean\u0000differences. From the obtaining result, it was concluded that weight training, aerobics and graded circuit training are\u0000found to be effective for reducing Abdominal Adiposity of overweight college girls.","PeriodicalId":19910,"journal":{"name":"Paripex Indian Journal Of Research","volume":"11 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140507617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"THE IMPACT OF BUSINESS INTELLIGENCE AND COMPETITIVE INTELLIGENCE IN MANAGEMENT: A BIBLIOMETRIC ANALYSIS","authors":"Nicolae Alexandru Budeanu","doi":"10.36106/paripex/2403035","DOIUrl":"https://doi.org/10.36106/paripex/2403035","url":null,"abstract":"The research in management field from the last decades showed that both knowledge and intelligence are considered as\u0000some of the most important assets which help business organizations achieve the competitive advantage in a certain\u0000market. In our current times, determined by uncertainty and ambiguity, leaders and managers are in a constant need of\u0000valuable and timely information that is required for taking the most desirable decision for the company. Given so,\u0000researchers and practitioners developed certain tools and activities in order to achieve the information necessary to\u0000decision making process, from both inside and outside the company, known as business intelligence and competitive\u0000intelligence. Therefore, this article contains a literature review about the connections between business intelligence,\u0000competitive intelligence, on one hand, and management, on the other hand. Using the specialized software VOSviewer,\u0000this research presents the bibliometric analysis based on the co-occurrences of certain keywords, which demonstrates\u0000the inter-correlation of some specific research fields. The data examined using VOSviewer was retrieved from Web of\u0000Science core collection, the world`s largest bibliographic database for scientific research.","PeriodicalId":19910,"journal":{"name":"Paripex Indian Journal Of Research","volume":"78 3-4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140507815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"\"FROM TREATMENT TO CHALLENGE: EXPLORING STEROID-INDUCED DIABETES MELLITUS – A COMPREHENSIVE CASE STUDY.\"","authors":"Krishna Upadhye, Uttam Kumar Aggarwal","doi":"10.36106/paripex/2303309","DOIUrl":"https://doi.org/10.36106/paripex/2303309","url":null,"abstract":"Steroid-induced diabetes mellitus (SIDM) represents a significant clinical challenge, arising as a consequence of\u0000glucocorticoid therapy commonly used in various medical conditions. Clinicians who want to reduce inflammation\u0000caused by immune system reactions commonly prescribe steroids. However, one significant side effect of steroid\u0000treatment is that patients' blood sugar levels rise. Long-term steroid use raises the risk of acquiring diabetes mellitus.\u0000Despite the widespread use of steroids for their anti-inflammatory and immunosuppressive properties,SIDM remains a\u0000common and potentially harmful complication that necessitates careful consideration in clinical practice. Two of the\u0000most often given steroids, cortisone and prednisone, increase the liver's ability to produce glucose and reduce cells'\u0000sensitivity to Insulin. This case study underscores the need for early detection and effective management of SIDM,\u0000emphasizing the importance of individualized treatment strategies.Furthermore,it highlights the gaps in understanding\u0000the impact of hyperglycemia associated with steroid use on clinical morbidity and mortality,urging for comprehensive\u0000guidelines to prevent complications and optimize patient outcomes in the context of the hyperglycemic state. The\u0000subject of this case study is a 53-year-old woman who was prescribed injections of methylprednisolone after being\u0000diagnosed with nephrotic syndrome. Her blood sugar levels noticeably increased after taking this medicine, which is\u0000consistent with the classic presentation of steroid-induced diabetes mellitus. This case study explores the complex\u0000relationship between steroids and diabetes mellitus, elucidating the mechanisms underlying hyperglycemia induced\u0000by glucocorticoids.","PeriodicalId":19910,"journal":{"name":"Paripex Indian Journal Of Research","volume":"7 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140508316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pranavi Reddy Gunamgari, Rajendhar Soorineedu, Raja shekar Reballi, Sivaprasad Kasimahanti
{"title":"RESILIENCE IN THE PRIMARY CAREGIVERS OF PATIENTS WITH SCHIZOPHRENIA, BIPOLAR AFFECTIVE DISORDER AND ALCOHOL DEPENDENCE SYNDROME","authors":"Pranavi Reddy Gunamgari, Rajendhar Soorineedu, Raja shekar Reballi, Sivaprasad Kasimahanti","doi":"10.36106/paripex/3400223","DOIUrl":"https://doi.org/10.36106/paripex/3400223","url":null,"abstract":"Caregivers who possess resilience are better able to manage and overcome adversity that comes with caring for a family\u0000member diagnosed with major mental illnesses like Schizophrenia,Bipolar Affective Disorder and Alcohol Dependence\u0000Syndrome.Family plays a key role in the care of patients with mental illnesses especially in India owing to the tradition of\u0000interdependence and the lack of sufficient mental health facilities making it important to understand the resilience of the\u0000caregiver in caring for the mentally ill. Aim:The aim of the present study is to study the resilience in primary caregivers\u0000of patients with Schizophrenia, Bipolar Affective Disorder and Alcohol dependence syndrome. Methods: The crosssectional comparative study included 90 primary caregivers of patients, 30 from each group. The diagnoses of the\u0000patients were confirmed with the MINI screen scale.A semi-structured interview was used to obtain demographic data\u0000and resilience in the caregivers was measured using the Connor Davidson Resilience Scale. Results: Resilience was\u0000found to be higher in males, mostly children of the patients hailing from higher income groups and carers with shared\u0000burden. Caregivers of the patients with schizophrenia were found to have higher resilience than those of the other 2\u0000groups. Conclusion: Gender, age, socioeconomic status, family support and diagnosis were all factors found to be\u0000influencing resilience in a caregiver.","PeriodicalId":19910,"journal":{"name":"Paripex Indian Journal Of Research","volume":"54 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140506936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. B. Rao, M. Rajesh, D. Swetha, G. M. Irfan, P. S. Reddy
{"title":"EFFICACY OF VIDEO-ASSISTED THORACOSCOPIC SURGERY (VATS) IN CHILDREN WITH EARLY EMPYEMA THORACIS IN COMPARISON TO OPEN THORACOTOMY","authors":"C. B. Rao, M. Rajesh, D. Swetha, G. M. Irfan, P. S. Reddy","doi":"10.36106/paripex/2500754","DOIUrl":"https://doi.org/10.36106/paripex/2500754","url":null,"abstract":"Background/Purpose: VATS is more effective in early empyema which includes exudative and early\u0000fibrinopurulent phase.This study evaluates the role of VATS and compares the results with open decortication\u0000cases done during the same period for early empyema thoracis. Method: A prospective study was done on\u0000children with empyema thoracis who underwent VATS from March 2017 to March 2020 in a single large center. The\u0000collected data included age, clinical presentation, radiological investigation, pleural fluid analysis, intraoperative\u0000findings,histopathological findings and post operative course.The length of stay and the post-operative time taken for\u0000clinical and radiological lung expansion was compared with cases of open decortication done for early empyema\u0000during the same period of study Results: Of the198 cases of empyema, 54 cases underwent VATS and open\u0000decortication was done in 130 children.Postoperatively patients became afebrile in 2 ± 1.2 days in VATS and 7 ± 3.2 days\u0000in open decortication.Clinical and radiological expansion was earlier in VATS with 3 ± 2.1 and 6 ± 2.2 days respectively.\u0000Conclusions: The prospective study concludes that VATS is more effective and less invasive than open thoracotomy for\u0000early empyema thoracis in decreasing the morbidity and has better cosmesis.","PeriodicalId":19910,"journal":{"name":"Paripex Indian Journal Of Research","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140507432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shashikala Lamani, N. Naik, Shabnam S, Peersab M Pinjar
{"title":"THE ROLE OF SERUM FERRITIN IN ANAEMIA – A KEY DIAGNOSTIC MARKER OF IRON DEFICIENCY","authors":"Shashikala Lamani, N. Naik, Shabnam S, Peersab M Pinjar","doi":"10.36106/paripex/7600803","DOIUrl":"https://doi.org/10.36106/paripex/7600803","url":null,"abstract":"Background and Objectives: Anaemia is a serious global public health problem. It is among the top leading causes of\u0000disability-adjusted life years lost among adolescents. The WHO has recognized Iron deficiency anemia as the most\u0000common nutritional deficiency in the world with 30% of the population being affected. Anemia has significant\u0000implications in terms of mortality as well as impaired work capacity and economic development. Serum ferritin plays a\u0000major role in diagnosis as well as management of anemia. 1. To study and interpret the iron paramet Objectives: ers in\u0000patients of anemia of Iron deficiency and anemia of chronic diseases. 2.To evaluate the role of serum ferritin over serum\u0000iron in early detection of iron deficiency. A cross-sectional study was undertaken during Material and Methods:\u0000February 2017 to August 2018. A total of 65 patients of anemia were included in the present study comprising 31 cases of\u0000Iron deficiency anemia and 34 cases of anemia of Chronic diseases. Serum ferritin was analyzed by chemiluminescent\u0000microparticle immunoassay technique in Abbott instrument. All other biochemical measurements were performed as\u0000per standard procedures. SPSS version 2.0 was used, Descriptive and inferential statistical analysis was done. Results:\u0000There was a high prevalence of anemia among the age group 21 to 40, that is 38.7%. In Iron deficiency anemia median\u0000and interquartile range values of serum Iron and serum ferritin were 45 and 51.0, 13 and 13.80 respectively. Spearman's\u0000correlation with serum ferritin was found to be significant in patients of iron deficiency anemia. The r value being 0.537\u0000and the p value 0.002. Spearman's correlation of serum ferritin with serum iron was found to be more significant in\u0000females. Serum ferritin can be used as an early marker in diagnosis of Iron deficiency anemia as we Conclusion: ll as in\u0000screening risk population, thus preventing associated morbidity and mortality","PeriodicalId":19910,"journal":{"name":"Paripex Indian Journal Of Research","volume":"16 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140508388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}