"FROM TREATMENT TO CHALLENGE: EXPLORING STEROID-INDUCED DIABETES MELLITUS – A COMPREHENSIVE CASE STUDY."

Abstract

Steroid-induced diabetes mellitus (SIDM) represents a significant clinical challenge, arising as a consequence of glucocorticoid therapy commonly used in various medical conditions. Clinicians who want to reduce inflammation caused by immune system reactions commonly prescribe steroids. However, one significant side effect of steroid treatment is that patients' blood sugar levels rise. Long-term steroid use raises the risk of acquiring diabetes mellitus. Despite the widespread use of steroids for their anti-inflammatory and immunosuppressive properties,SIDM remains a common and potentially harmful complication that necessitates careful consideration in clinical practice. Two of the most often given steroids, cortisone and prednisone, increase the liver's ability to produce glucose and reduce cells' sensitivity to Insulin. This case study underscores the need for early detection and effective management of SIDM, emphasizing the importance of individualized treatment strategies.Furthermore,it highlights the gaps in understanding the impact of hyperglycemia associated with steroid use on clinical morbidity and mortality,urging for comprehensive guidelines to prevent complications and optimize patient outcomes in the context of the hyperglycemic state. The subject of this case study is a 53-year-old woman who was prescribed injections of methylprednisolone after being diagnosed with nephrotic syndrome. Her blood sugar levels noticeably increased after taking this medicine, which is consistent with the classic presentation of steroid-induced diabetes mellitus. This case study explores the complex relationship between steroids and diabetes mellitus, elucidating the mechanisms underlying hyperglycemia induced by glucocorticoids.