Pain Research and Treatment最新文献_第7页

A Clinical Experimental Model to Evaluate Analgesic Effect of Remote Ischemic Preconditioning in Acute Postoperative Pain. 远距离缺血预处理对急性术后疼痛镇痛作用的临床实验模型研究。

Pain Research and Treatment Pub Date : 2016-01-01 Epub Date: 2016-06-30 DOI: 10.1155/2016/5093870

Francisco Elano Carvalho Pereira, Irene Lopes Mello, Fernando Heladio de Oliveira Medeiros Pimenta, Debora Maia Costa, Deysi Viviana Tenazoa Wong, Claudia Regina Fernandes, Roberto César Lima Junior, Josenília M Alves Gomes

{"title":"A Clinical Experimental Model to Evaluate Analgesic Effect of Remote Ischemic Preconditioning in Acute Postoperative Pain.","authors":"Francisco Elano Carvalho Pereira, Irene Lopes Mello, Fernando Heladio de Oliveira Medeiros Pimenta, Debora Maia Costa, Deysi Viviana Tenazoa Wong, Claudia Regina Fernandes, Roberto César Lima Junior, Josenília M Alves Gomes","doi":"10.1155/2016/5093870","DOIUrl":"https://doi.org/10.1155/2016/5093870","url":null,"abstract":"This study aims to evaluate the viability of a clinical model of remote ischemic preconditioning (RIPC) and its analgesic effects. It is a prospective study with twenty (20) patients randomly divided into two groups: control group and RIPC group. The opioid analgesics consumption in the postoperative period, the presence of secondary mechanical hyperalgesia, the scores of postoperative pain by visual analog scale, and the plasma levels interleukins (IL-6) were evaluated. The tourniquet applying after spinal anesthetic block was safe, producing no pain for all patients in the tourniquet group. The total dose of morphine consumption in 24 hours was significantly lower in RIPC group than in the control group (p = 0.0156). The intensity analysis of rest pain, pain during coughing and pain in deep breathing, showed that visual analogue scale (VAS) scores were significantly lower in RIPC group compared to the control group: p = 0.0087, 0.0119, and 0.0015, respectively. There were no differences between groups in the analysis of presence or absence of mechanical hyperalgesia (p = 0.0704) and in the serum levels of IL-6 dosage over time (p < 0.0001). This clinical model of remote ischemic preconditioning promoted satisfactory analgesia in patients undergoing conventional cholecystectomy, without changing serum levels of IL-6. ","PeriodicalId":19786,"journal":{"name":"Pain Research and Treatment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2016/5093870","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34693075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

The Efficacy of Interdisciplinary Rehabilitation for Improving Function in People with Chronic Pain. 跨学科康复对改善慢性疼痛患者功能的疗效。

Pain Research and Treatment Pub Date : 2016-01-01 Epub Date: 2016-05-08 DOI: 10.1155/2016/7217684

Svetlana Kurklinsky, Rachel B Perez, Elke R Lacayo, Christopher D Sletten

{"title":"The Efficacy of Interdisciplinary Rehabilitation for Improving Function in People with Chronic Pain.","authors":"Svetlana Kurklinsky, Rachel B Perez, Elke R Lacayo, Christopher D Sletten","doi":"10.1155/2016/7217684","DOIUrl":"10.1155/2016/7217684","url":null,"abstract":"Objective. To examine the efficacy of interdisciplinary rehabilitation for improving function in people with chronic pain. Design. Retrospective Chart Review. Setting. The Pain Rehabilitation Center (PRC) at a medical center. Participants. Individuals admitted to the PRC. Interventions. The PRC operates a 3-week outpatient program that utilizes an interdisciplinary approach to treat people with chronic pain. The main treatment elements include physical therapy, occupational therapy, cognitive behavioral therapy (CBT), and medication management. Physical therapy groups focus on moderate exercise despite symptoms. Occupational therapists teach moderation, time management, and activity modification. CBT groups, led by a pain psychologist, address the psychosocial comorbidities of chronic pain. Medical staff oversee the tapering of opiate analgesics and other symptom targeted treatments. This integrated approach is indicated when conventional treatments have been ineffective. Outcome Measures. The objective outcome was the 6-minute walk test (6 mWT) distance. The subjective outcomes were performance (COPM-PER) and satisfaction (COPM-SAT) as measured by the Canadian Occupational Performance Measure (COPM). Results. Average 6 mWT distances improved by 39% from 375 m to 523 m. Average COPM-PER scores increased from 3.4 to 7.5. Average COPM-SAT scores increased from 2.4 to 7.5. Conclusions. Comprehensive interdisciplinary outpatient rehabilitation can significantly improve function in people with chronic pain. ","PeriodicalId":19786,"journal":{"name":"Pain Research and Treatment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2016/7217684","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34533402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 39

Experiences of Iranian Nurses on the Facilitators of Pain Management in Children: A Qualitative Study. 伊朗护士对儿童疼痛管理促进者的经验:一项定性研究。

Pain Research and Treatment Pub Date : 2016-01-01 Epub Date: 2016-03-30 DOI: 10.1155/2016/3594240

Parvin Aziznejadroshan, Fatemeh Alhani, Eesa Mohammadi

{"title":"Experiences of Iranian Nurses on the Facilitators of Pain Management in Children: A Qualitative Study.","authors":"Parvin Aziznejadroshan, Fatemeh Alhani, Eesa Mohammadi","doi":"10.1155/2016/3594240","DOIUrl":"https://doi.org/10.1155/2016/3594240","url":null,"abstract":"Background. Despite decades of research and the availability of effective analgesic approaches, many children continue to experience moderate-to-severe pain after hospitalization. Greater research efforts are needed to identify the factors that facilitate effective pain management. The aim of this study was to explore the perceptions of Iranian nurses on facilitators of pain management in children. Materials and Methods. This qualitative study collected the data profoundly through unstructured interviews with 19 nurses in Amirkola Children's Hospital in Babol and Children's Medical Center in Tehran, during 2013-2014. Purposeful sampling and analysis of the data were conducted using conventional qualitative content analysis. Results. Four themes were extracted through data analysis: mother and child participation in diagnosis and pain relief, the timely presence of medical staff and parents, proper communication, and training and supportive role of nurses. Conclusion. Mother and child participation in the report and diagnosis of pain and nonpharmacological interventions for pain by the mother, the timely presence of medical team at the patient's bedside, and proper interaction along with the training and supportive role of a nurse enhanced the optimal pain management in hospitalized children. ","PeriodicalId":19786,"journal":{"name":"Pain Research and Treatment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2016/3594240","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34498722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

Increased Risk of Postthoracotomy Pain Syndrome in Patients with Prolonged Hospitalization and Increased Postoperative Opioid Use. 延长住院时间和术后阿片类药物使用增加的患者开胸后疼痛综合征的风险增加。

Pain Research and Treatment Pub Date : 2016-01-01 Epub Date: 2016-06-02 DOI: 10.1155/2016/7945145

Michelle A O Kinney, Adam K Jacob, Melissa A Passe, Carlos B Mantilla

{"title":"Increased Risk of Postthoracotomy Pain Syndrome in Patients with Prolonged Hospitalization and Increased Postoperative Opioid Use.","authors":"Michelle A O Kinney, Adam K Jacob, Melissa A Passe, Carlos B Mantilla","doi":"10.1155/2016/7945145","DOIUrl":"https://doi.org/10.1155/2016/7945145","url":null,"abstract":"Background. Postthoracotomy pain syndrome (PTPS) is unfortunately very common following thoracotomy and results in decreased quality of life. The purpose of this retrospective study was to determine perioperative patient, surgical, and analgesic characteristics associated with the development of PTPS. Methods. Sixty-six patients who presented to the Mayo Clinic Rochester Pain Clinic were diagnosed with PTPS 2 months or more after thoracotomy with postoperative epidural analgesia. These patients were matched with sixty-six control patients who underwent thoracotomy with postoperative epidural analgesia and were never diagnosed with PTPS. Results. Median (IQR) hospital stay was significantly different between control patients (5 days (4, 6)) compared with PTPS patients (6 days (5, 8)), P < 0.02. The total opioid equivalent utilized in oral morphine equivalents in milligrams for the first three days postoperatively was significantly different between control patients and PTPS patients. The median (IQR) total opioid equivalent utilized was 237 (73, 508) for controls and 366 (116, 874) for PTPS patients (P < 0.005). Conclusion. Patients with a prolonged hospital stay after thoracotomy were at an increased risk of developing PTPS, and this is a novel finding. Patients who utilize higher oral morphine equivalents for the first 3 days were also at increased risk for PTPS. ","PeriodicalId":19786,"journal":{"name":"Pain Research and Treatment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2016/7945145","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34606502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

Load Handling and Repetitive Movements Are Associated with Chronic Low Back Pain among Jute Mill Workers in India. 负荷搬运和重复性运动与印度黄麻厂工人的慢性腰痛有关。

Pain Research and Treatment Pub Date : 2016-01-01 Epub Date: 2016-08-02 DOI: 10.1155/2016/7843216

S Goswami, S Dasgupta, A Samanta, G Talukdar, A Chanda, P Ray Karmakar, A Majumdar, D Bhattacharya, A Chakrabarti

{"title":"Load Handling and Repetitive Movements Are Associated with Chronic Low Back Pain among Jute Mill Workers in India.","authors":"S Goswami, S Dasgupta, A Samanta, G Talukdar, A Chanda, P Ray Karmakar, A Majumdar, D Bhattacharya, A Chakrabarti","doi":"10.1155/2016/7843216","DOIUrl":"https://doi.org/10.1155/2016/7843216","url":null,"abstract":"Introduction. WHO recognizes low back pain as one of the most important ergonomic stressors. Therefore, the present study was designed to find out the magnitude of the problem among jute mill workers in India and identify possible associations. Methodology. This cross-sectional workplace based study was conducted among eight (8) selected jute mills of India. Subjects with self-reported back pain for at least last 12 weeks were included and n = 717 male jute mill workers actively engaged in work entered the study and completed all assessments. Results. Among all participants 55% (n = 392) had current chronic low back pain. Age was an important association with subjects in the age group of 40–59 years more likely to have pain (p = 0.02, OR 1.44). Regarding ergonomic risk factors lifting of load of more than 20 kg (p = 0.04, OR 1.42) and repetitive movements of limbs (p = 0.03, OR 0.67) were significant associations of chronic low back pain. Conclusion. This study identified a significant prevalence of current chronic low back pain among jute mill workers. Regarding ergonomic risk factors the present study has identified two significant associations: lifting of load above 20 kg and repetitive movements of limbs. Therefore, this study has identified need for workplace interventions in this occupational group employing approximately 3,50,000 workers in India.","PeriodicalId":19786,"journal":{"name":"Pain Research and Treatment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2016/7843216","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34337817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

Impact of Opioid and Nonopioid Drugs on Postsurgical Pain Management in the Rat. 阿片类药物和非阿片类药物对大鼠术后疼痛管理的影响。

Pain Research and Treatment Pub Date : 2016-01-01 Epub Date: 2016-03-16 DOI: 10.1155/2016/8364762

Natalie M Wilson, Matthew S Ripsch, Fletcher A White

{"title":"Impact of Opioid and Nonopioid Drugs on Postsurgical Pain Management in the Rat.","authors":"Natalie M Wilson, Matthew S Ripsch, Fletcher A White","doi":"10.1155/2016/8364762","DOIUrl":"https://doi.org/10.1155/2016/8364762","url":null,"abstract":"Aim. Nonsteroidal anti-inflammatory drugs or opioids are commonly used to control surgical pain following veterinary and clinical procedures. This study evaluated the efficacy of postoperative ketorolac or buprenorphine following abdominal surgery. Main Methods. Mean arterial pressure (MAP), heart rate, animal activity, corticosterone levels, and a nociceptive sensitivity assay were used to evaluate 18 adult male Sprague-Dawley rats which underwent aortic artery occlusion for implantation of a radiotelemetry device. The animals were treated postoperatively with intraperitoneal injections of vehicle, ketorolac (10 mg/kg), or buprenorphine (0.06 mg/kg) every 8 hours for 3 days. Key Findings. There were no consistent significant changes in any of the telemetry parameters after treatment with ketorolac compared with no saline treatment with the exception of increased MAP in the buprenorphine group during the first 48 hours when compared with other treatment groups. There was a sustained increase in fecal corticosterone levels from baseline on days 2-7 with buprenorphine compared with vehicle- or ketorolac-treated animals. All treatment conditions displayed reduced paw withdrawal thresholds (PWTs) from day 1 to day 21 following surgery. Compared with the vehicle treatment group, buprenorphine-treated animals exhibited significantly lower PWT levels from day 4 to 14 days. Significance. Given the prolonged increase in fecal corticosterone levels and pronounced changes in tactile hyperalgesia behavior in rodents subjected to buprenorphine treatment, these data suggest that ketorolac may be superior to buprenorphine for the treatment of postprocedure pain behavior in rodents. ","PeriodicalId":19786,"journal":{"name":"Pain Research and Treatment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2016/8364762","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34393832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Chronic Neck Pain and Cervico-Craniofacial Pain Patients Express Similar Levels of Neck Pain-Related Disability, Pain Catastrophizing, and Cervical Range of Motion. 慢性颈部疼痛和颈颅面疼痛患者表现出相似程度的颈部疼痛相关残疾、疼痛灾难化和颈椎活动范围。

Pain Research and Treatment Pub Date : 2016-01-01 Epub Date: 2016-03-29 DOI: 10.1155/2016/7296032

Daniel Muñoz-García, Alfonso Gil-Martínez, Almudena López-López, Ibai Lopez-de-Uralde-Villanueva, Roy La Touche, Josué Fernández-Carnero

{"title":"Chronic Neck Pain and Cervico-Craniofacial Pain Patients Express Similar Levels of Neck Pain-Related Disability, Pain Catastrophizing, and Cervical Range of Motion.","authors":"Daniel Muñoz-García, Alfonso Gil-Martínez, Almudena López-López, Ibai Lopez-de-Uralde-Villanueva, Roy La Touche, Josué Fernández-Carnero","doi":"10.1155/2016/7296032","DOIUrl":"https://doi.org/10.1155/2016/7296032","url":null,"abstract":"Background. Neck pain (NP) is strongly associated with cervico-craniofacial pain (CCFP). The primary aim of the present study was to compare the neck pain-related disability, pain catastrophizing, and cervical and mandibular ROM between patients with chronic mechanical NP and patients with CCFP, as well as asymptomatic subjects. Methods. A total of 64 participants formed three groups. All participants underwent a clinical examination evaluating the cervical range of motion and maximum mouth opening, neck disability index (NDI), and psychological factor of Pain Catastrophizing Scale (PCS). Results. There were no statistically significant differences between patients with NP and CCFP for NDI and PCS (P > 0.05). One- way ANOVA revealed significant differences for all ROM measurements. The post hoc analysis showed no statistically significant differences in cervical extension and rotation between the two patient groups (P > 0.05). The Pearson correlation analysis shows a moderate positive association between NDI and the PCS for the group of patients with NP and CCFP. Conclusion. The CCFP and NP patient groups have similar neck disability levels and limitation in cervical ROM in extension and rotation. Both groups had positively correlated the NDI with the PCS. ","PeriodicalId":19786,"journal":{"name":"Pain Research and Treatment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2016/7296032","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34436152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 30

Open versus Laparoscopic Surgery: Does the Surgical Technique Influence Pain Outcome? Results from an International Registry. 开放式与腹腔镜手术:手术技术是否影响疼痛结局?来自国际注册的结果。

Pain Research and Treatment Pub Date : 2016-01-01 Epub Date: 2016-03-22 DOI: 10.1155/2016/4087325

Renée Allvin, Narinder Rawal, Eva Johanzon, Ragnar Bäckström

{"title":"Open versus Laparoscopic Surgery: Does the Surgical Technique Influence Pain Outcome? Results from an International Registry.","authors":"Renée Allvin, Narinder Rawal, Eva Johanzon, Ragnar Bäckström","doi":"10.1155/2016/4087325","DOIUrl":"https://doi.org/10.1155/2016/4087325","url":null,"abstract":"Postoperative pain management relevant for specific surgical procedures is debated. The importance of evaluating pain with consideration given to type of surgery and the patient's perspective has been emphasized. In this prospective cohort study, we analysed outcome data from 607 patients in the international PAIN OUT registry for assessment and comparison of postoperative pain outcome within the 24 first hours after laparoscopic and open colonic surgery. Patients from the laparoscopic group scored minimum pain at a higher level than the open group (P = 0.012). Apart from minimum pain, no other significant differences in patient reported outcomes were observed. Maximum pain scores >3 were reported from 77% (laparoscopic) and 68% (open) patients (mean ≥ 5 in both groups). Pain interference with mobilization was reported by 87-93% of patients. Both groups scored high levels of patient satisfaction. In the open group, a higher frequency of patients received a combination of general and regional anaesthesia, which had an impact of the minimum pain score. Our results from registry data indicate that surgical technique does not influence the quality of postoperative pain management during the first postoperative day if adequate analgesia is given. ","PeriodicalId":19786,"journal":{"name":"Pain Research and Treatment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2016/4087325","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34441333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 14

Treatment of Refractory Postdural Puncture Headache after Intrathecal Drug Delivery System Implantation with Epidural Blood Patch Procedures: A 20-Year Experience. 硬膜外血液贴片治疗鞘内药物输送系统植入后顽固性硬脊膜后穿刺头痛:20年的经验。

Pain Research and Treatment Pub Date : 2016-01-01 Epub Date: 2016-08-11 DOI: 10.1155/2016/2134959

Markus A Bendel, Susan M Moeschler, Wenchun Qu, Eugerie Hanley, Stephanie A Neuman, Jason S Eldrige, Bryan C Hoelzer

{"title":"Treatment of Refractory Postdural Puncture Headache after Intrathecal Drug Delivery System Implantation with Epidural Blood Patch Procedures: A 20-Year Experience.","authors":"Markus A Bendel, Susan M Moeschler, Wenchun Qu, Eugerie Hanley, Stephanie A Neuman, Jason S Eldrige, Bryan C Hoelzer","doi":"10.1155/2016/2134959","DOIUrl":"https://doi.org/10.1155/2016/2134959","url":null,"abstract":"A recent publication reported the incidence of postdural puncture headache (PDPH) in conjunction with intrathecal drug delivery system (IDDS) implantation to be nearly 23 percent. Many patients responded to conservative measures but a percentage needed invasive treatment with an epidural blood patch (EBP). There is limited data to describe the technical details, success rates, and complications associated with EBP in this population. This study aims to provide a retrospective report of EBP for patients suffering from PDPH related to IDDS implantation. A chart review established a cohort of patients that required EBP in relation to a PDPH after IDDS implantation. This cohort was evaluated for demographic data as well as details of the EBP including technical procedural data, success rates, and complications. All patients received a trial of conservative therapy. Standard sterile technique and skin preparation were utilized with no infectious complications. The EBP was placed below the level of the IDDS catheter in 94% of procedures. Fluoroscopy was utilized in each case. The mean EBP volume was 18.6 cc and median time of EBP was day 7 after implant. There were no complications associated with EBP. EBP appears to be an effective intervention in this subset of PDPH patients. ","PeriodicalId":19786,"journal":{"name":"Pain Research and Treatment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2016/2134959","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34710462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

Cost-Saving Early Diagnosis of Functional Pain in Nonmalignant Pain: A Noninferiority Study of Diagnostic Accuracy. 功能性疼痛在非恶性疼痛中的早期诊断:诊断准确性的非劣效性研究。

Pain Research and Treatment Pub Date : 2016-01-01 Epub Date: 2016-03-21 DOI: 10.1155/2016/5964250

Rafael J A Cámara, Christian Merz, Barbara Wegmann, Stefanie Stauber, Roland von Känel, Niklaus Egloff

{"title":"Cost-Saving Early Diagnosis of Functional Pain in Nonmalignant Pain: A Noninferiority Study of Diagnostic Accuracy.","authors":"Rafael J A Cámara, Christian Merz, Barbara Wegmann, Stefanie Stauber, Roland von Känel, Niklaus Egloff","doi":"10.1155/2016/5964250","DOIUrl":"https://doi.org/10.1155/2016/5964250","url":null,"abstract":"Objectives. We compared two index screening tests for early diagnosis of functional pain: pressure pain measurement by electronic diagnostic equipment, which is accurate but too specialized for primary health care, versus peg testing, which is cost-saving and more easily manageable but of unknown sensitivity and specificity. Early distinction of functional (altered pain perception; nervous sensitization) from neuropathic or nociceptive pain improves pain management. Methods. Clinicians blinded for the index screening tests assessed the reference standard of this noninferiority diagnostic accuracy study, namely, comprehensive medical history taking with all previous findings and treatment outcomes. All consenting patients referred to a university hospital for nonmalignant musculoskeletal pain participated. The main analysis compared the receiver operating characteristic (ROC) curves of both index screening tests. Results. The area under the ROC curve for peg testing was not inferior to that of electronic equipment: it was at least 95% as large for finger measures (two-sided p = 0.038) and at least equally as large for ear measures (two-sided p = 0.003). Conclusions. Routine diagnostic testing by peg, which is accessible for general practitioners, is at least as accurate as specialized equipment. This may shorten time-to-treatment in general practices, thereby improving the prognosis and quality of life. ","PeriodicalId":19786,"journal":{"name":"Pain Research and Treatment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2016/5964250","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34411804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7