Pain Research and Treatment最新文献_第10页

Vitamin D and Pain: Vitamin D and Its Role in the Aetiology and Maintenance of Chronic Pain States and Associated Comorbidities. 维生素D与疼痛:维生素D及其在慢性疼痛状态和相关合并症的病因学和维持中的作用。

Pain Research and Treatment Pub Date : 2015-01-01 Epub Date: 2015-04-19 DOI: 10.1155/2015/904967

Edward A Shipton, Elspeth E Shipton

引用次数: 84

Mastalgia: prevalence at a sub-saharan african tertiary hospital. 乳房痛:撒哈拉以南非洲某三级医院的流行情况。

Pain Research and Treatment Pub Date : 2014-01-01 Epub Date: 2014-09-30 DOI: 10.1155/2014/972726

T Makumbi, M Galukande, A Gakwaya

{"title":"Mastalgia: prevalence at a sub-saharan african tertiary hospital.","authors":"T Makumbi, M Galukande, A Gakwaya","doi":"10.1155/2014/972726","DOIUrl":"https://doi.org/10.1155/2014/972726","url":null,"abstract":"Introduction. Mastalgia is a common breast condition among women referred to breast clinics worldwide. Whereas the prevalence is known in the Western world and Asia, the prevalence of the disease is unknown in many African countries. The aim of this study therefore was to determine the prevalence and describe factors associated with mastalgia among women attending a tertiary hospital in sub-Saharan Africa. Methods. A cross-sectional study was done in Kampala, Uganda. Mastalgia was defined as self-reported breast pain (unilateral or bilateral) for a period not less than two months. A pretested questionnaire was used to collect the data and statistical analysis was performed using SPSS version 11. Ethical approval was obtained. Results. Out of the 1048 women who presented to the breast clinic during the study period, 168 (16%) were diagnosed with mastalgia in the absence of breast cancer. Noncyclical and cyclical mastalgia were 22/168 (13%) and 5/168 (3%), respectively. The onset of noncyclical category as compared to the cyclical type of mastalgia was observed to manifest before 24 years of age (P = 0.006). Conclusion. Mastalgia was a common condition among women in this sub-Saharan African setting as is elsewhere. The early onset mastalgia in this sub-Saharan African study requires further exploration for determination of its risk factors. ","PeriodicalId":19786,"journal":{"name":"Pain Research and Treatment","volume":"2014 ","pages":"972726"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/972726","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32775718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Effect of Platelet-Rich Plasma (PRP) versus Autologous Whole Blood on Pain and Function Improvement in Tennis Elbow: A Randomized Clinical Trial. 富血小板血浆(PRP)与自体全血对网球肘疼痛和功能改善的影响:一项随机临床试验。

Pain Research and Treatment Pub Date : 2014-01-01 Epub Date: 2014-01-20 DOI: 10.1155/2014/191525

Seyed Ahmad Raeissadat, Leyla Sedighipour, Seyed Mansoor Rayegani, Mohammad Hasan Bahrami, Masume Bayat, Rosa Rahimi

{"title":"Effect of Platelet-Rich Plasma (PRP) versus Autologous Whole Blood on Pain and Function Improvement in Tennis Elbow: A Randomized Clinical Trial.","authors":"Seyed Ahmad Raeissadat, Leyla Sedighipour, Seyed Mansoor Rayegani, Mohammad Hasan Bahrami, Masume Bayat, Rosa Rahimi","doi":"10.1155/2014/191525","DOIUrl":"https://doi.org/10.1155/2014/191525","url":null,"abstract":"Background. Autologous whole blood and platelet-rich plasma (PRP) have been both suggested to treat chronic tennis elbow. The aim of the present study was to compare the effects of PRP versus autologous whole blood local injection in chronic tennis elbow. Methods. Forty patients with tennis elbow were randomly divided into 2 groups. Group 1 was treated with a single injection of 2 mL of autologous PRP and group 2 with 2 mL of autologous blood. Tennis elbow strap, stretching, and strengthening exercises were administered for both groups during a 2-month followup. Pain and functional improvements were assessed using visual analog scale (VAS), modified Mayo Clinic performance index for the elbow, and pressure pain threshold (PPT) at 0, 4, and 8 weeks. Results. All pain and functional variables including VAS, PPT, and Mayo scores improved significantly in both groups 4 weeks after injection. No statistically significant difference was noted between groups regarding pain scores in 4-week follow-up examination (P > 0.05). At 8-week reevaluations, VAS and Mayo scores improved only in PRP group (P < 0.05). Conclusion. PRP and autologous whole blood injections are both effective to treat chronic lateral epicondylitis. PRP might be slightly superior in 8-week followup. However, further studies are suggested to get definite conclusion. ","PeriodicalId":19786,"journal":{"name":"Pain Research and Treatment","volume":"2014 ","pages":"191525"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/191525","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32163810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 58

Can fluctuations in vital signs be used for pain assessment in critically ill patients with a traumatic brain injury? 生命体征波动可用于脑外伤重症患者的疼痛评估吗？

Pain Research and Treatment Pub Date : 2014-01-01 Epub Date: 2014-01-22 DOI: 10.1155/2014/175794

Caroline Arbour, Manon Choinière, Jane Topolovec-Vranic, Carmen G Loiselle, Céline Gélinas

{"title":"Can fluctuations in vital signs be used for pain assessment in critically ill patients with a traumatic brain injury?","authors":"Caroline Arbour, Manon Choinière, Jane Topolovec-Vranic, Carmen G Loiselle, Céline Gélinas","doi":"10.1155/2014/175794","DOIUrl":"10.1155/2014/175794","url":null,"abstract":"Background. Many critically ill patients with a traumatic brain injury (TBI) are unable to communicate. While observation of behaviors is recommended for pain assessment in nonverbal populations, they are undetectable in TBI patients who are under the effects of neuroblocking agents. Aim. This study aimed to validate the use of vital signs for pain detection in critically ill TBI patients. Methods. Using a repeated measure within subject design, participants (N = 45) were observed for 1 minute before (baseline), during, and 15 minutes after two procedures: noninvasive blood pressure: NIBP (nonnociceptive) and turning (nociceptive). At each assessment, vital signs (e.g., systolic, diastolic, mean arterial pressure (MAP), heart rate (HR), respiratory rate (RR), capillary saturation (SpO2), end-tidal CO2, and intracranial pressure (ICP)) were recorded. Results. Significant fluctuations (P < 0.05) in diastolic (F = 6.087), HR (F = 3.566), SpO2 (F = 5.740), and ICP (F = 3.776) were found across assessments, but they were similar during both procedures. In contrast, RR was found to increase exclusively during turning (t = 3.933; P < 0.001) and was correlated to participants' self-report. Conclusions. Findings from this study support previous ones that vital signs are not specific for pain detection. While RR could be a potential pain indicator in critical care, further research is warranted to support its validity in TBI patients with different LOC. ","PeriodicalId":19786,"journal":{"name":"Pain Research and Treatment","volume":"2014 ","pages":"175794"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929987/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32183501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intra-Articular Analgesia and Steroid Reduce Pain Sensitivity in Knee OA Patients: An Interventional Cohort Study. 关节内镇痛和类固醇降低膝关节OA患者疼痛敏感性:一项介入性队列研究。

Pain Research and Treatment Pub Date : 2014-01-01 Epub Date: 2014-05-07 DOI: 10.1155/2014/710490

Tanja Schjødt Jørgensen, Thomas Graven-Nielsen, Karen Ellegaard, Bente Danneskiold-Samsøe, Henning Bliddal, Marius Henriksen

{"title":"Intra-Articular Analgesia and Steroid Reduce Pain Sensitivity in Knee OA Patients: An Interventional Cohort Study.","authors":"Tanja Schjødt Jørgensen, Thomas Graven-Nielsen, Karen Ellegaard, Bente Danneskiold-Samsøe, Henning Bliddal, Marius Henriksen","doi":"10.1155/2014/710490","DOIUrl":"https://doi.org/10.1155/2014/710490","url":null,"abstract":"Objectives. To assess the effects of intra-articular therapy on pain sensitivity in the knee and surrounding tissues in knee OA patients. Methods. Twenty-five knee OA patients with symptomatic knee OA were included in this interventional cohort study. Pressure pain thresholds (PPT) were recorded before, immediately after, and two weeks after ultrasound guided intra-articular injection of lidocaine combined with glucocorticosteroid. Computer-controlled and manual pressure algometers were used to assess PPT on the knee, vastus lateralis, tibialis anterior, and the extensor carpi radialis longus muscles (control site). Results. Significantly increased PPTs were found following intra-articular injection, at both the knee (P < 0.0001) and the surrounding muscles (P < 0.042). The treatment effects were sustained for two weeks, and at some points the effect was even greater at two weeks (P < 0.026). Albeit not statistically significant, a similar trend was observed at the control site. Conclusions. Intra-articular anesthesia, combined with glucocorticosteroid, reduced pain sensitivity in both the knee and surrounding muscles for at least two weeks. ","PeriodicalId":19786,"journal":{"name":"Pain Research and Treatment","volume":"2014 ","pages":"710490"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/710490","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32394424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 21

Etiology and use of the "hanging drop" technique: a review. “吊滴法”的病因及应用综述。

Pain Research and Treatment Pub Date : 2014-01-01 Epub Date: 2014-04-15 DOI: 10.1155/2014/146750

Ludmil Todorov, Timothy VadeBoncouer

{"title":"Etiology and use of the \"hanging drop\" technique: a review.","authors":"Ludmil Todorov, Timothy VadeBoncouer","doi":"10.1155/2014/146750","DOIUrl":"https://doi.org/10.1155/2014/146750","url":null,"abstract":"Background. The hanging drop (HD) technique presumably relies on the presence of subatmospheric epidural pressure. It is not clear whether this negative pressure is intrinsic or an artifact and how it is affected by body position. There are few data to indicate how often HD is currently being used. Methods. We identified studies that measured subatmospheric pressures and looked at the effect of the sitting position. We also looked at the technique used for cervical and thoracic epidural anesthesia in the last 10 years. Results. Intrinsic subatmospheric pressures were measured in the thoracic and cervical spine. Three trials studied the effect of body position, indicating a higher incidence of subatmospheric pressures when sitting. The results show lower epidural pressure (-10.7 mmHg) with the sitting position. 28.8% of trials of cervical and thoracic epidural anesthesia that documented the technique used, utilized the HD technique. When adjusting for possible bias, the rate of HD use can be as low as 11.7%. Conclusions. Intrinsic negative pressure might be present in the cervical and thoracic epidural space. This effect is more pronounced when sitting. This position might be preferable when using HD. Future studies are needed to compare it with the loss of resistance technique. ","PeriodicalId":19786,"journal":{"name":"Pain Research and Treatment","volume":"2014 ","pages":"146750"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/146750","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32352238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 24

Topical anesthesia for cataract surgery: the patients' perspective. 白内障手术的表面麻醉:患者的视角。

Pain Research and Treatment Pub Date : 2014-01-01 Epub Date: 2014-06-24 DOI: 10.1155/2014/827659

Aytekin Apil, Baki Kartal, Metin Ekinci, Halil Huseyin Cagatay, Sadullah Keles, Erdinc Ceylan, Ozgur Cakici

引用次数: 15

The Beliefs of Third-Level Healthcare Students towards Low-Back Pain. 三级保健生对腰痛的信念。

Pain Research and Treatment Pub Date : 2014-01-01 Epub Date: 2014-04-10 DOI: 10.1155/2014/675915

Norelee Kennedy, John Healy, Kieran O'Sullivan

{"title":"The Beliefs of Third-Level Healthcare Students towards Low-Back Pain.","authors":"Norelee Kennedy, John Healy, Kieran O'Sullivan","doi":"10.1155/2014/675915","DOIUrl":"https://doi.org/10.1155/2014/675915","url":null,"abstract":"Objectives. Beliefs held by healthcare providers are part of the complex recovery of a patient with low-back pain (LBP). The aim of this study was to investigate the attitudes and beliefs of Irish university healthcare students towards LBP. Methods. Physiotherapy (n = 107), medicine (n = 63), nursing, and midwifery (n = 101) students completed the survey. Demographic data, LBP related beliefs [Back Beliefs Questionnaire (BBQ) and the Fear Avoidance Beliefs Questionnaire physical subsection (FABQ-PA)] were collected. Results. Two hundred and seventy-one students responded (response rate 29%). Student physiotherapists had significantly lower FABQ (P < 0.001) scores than medical (95% CI [-5.492, -1.406]) and nursing students (95% CI [-7.718, -22.307]). Physiotherapy students had significantly higher BBQ scores (P < 0.0001) than medical (95% CI [1.490, 5.406]) and nursing students (95% CI [6.098, 11.283]). Beliefs of physiotherapy and medical students were significantly better among fourth-year year than first-year students (P < 0.0001) but were not significantly different for nursing students (P = 0.820 for FABQ and P = 0.810 for BBQ). Conclusions. Physiotherapy students had more positive beliefs towards LBP than medical and nursing students. Physiotherapy and medical students' beliefs towards LBP significantly improved over the course of their studies. ","PeriodicalId":19786,"journal":{"name":"Pain Research and Treatment","volume":"2014 ","pages":"675915"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/675915","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32332616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 26

Micronized palmitoylethanolamide reduces the symptoms of neuropathic pain in diabetic patients. 微粉化棕榈酰乙醇酰胺可减轻糖尿病患者神经性疼痛症状。

Pain Research and Treatment Pub Date : 2014-01-01 Epub Date: 2014-04-02 DOI: 10.1155/2014/849623

Chiara Schifilliti, Lelio Cucinotta, Viviana Fedele, Carmela Ingegnosi, Salvatore Luca, Carmelo Leotta

{"title":"Micronized palmitoylethanolamide reduces the symptoms of neuropathic pain in diabetic patients.","authors":"Chiara Schifilliti, Lelio Cucinotta, Viviana Fedele, Carmela Ingegnosi, Salvatore Luca, Carmelo Leotta","doi":"10.1155/2014/849623","DOIUrl":"https://doi.org/10.1155/2014/849623","url":null,"abstract":"The present study evaluated the effectiveness of micronized palmitoylethanolamide (PEA-m) treatment in reducing the painful symptoms experienced by diabetic patients with peripheral neuropathy. PEA-m, a fatty acid amide of the N-acylethanolamine family, was administered (300 mg twice daily) to 30 diabetic patients suffering from painful diabetic neuropathy. Before treatment start, after 30 and 60 days the following parameters were assessed: painful symptoms of diabetic peripheral neuropathy using the Michigan Neuropathy Screening instrument; intensity of symptoms characteristic of diabetic neuropathic pain by the Total Symptom Score; and intensity of different subcategories of neuropathic pain by the Neuropathic Pain Symptoms Inventory. Hematological and blood chemistry tests to evaluate metabolic control and safety were also performed. Statistical analysis (ANOVA) indicated a highly significant reduction in pain severity (P < 0.0001) and related symptoms (P < 0.0001) evaluated by Michigan Neuropathy Screening instrument, Total Symptom Score, and Neuropathic Pain Symptoms Inventory. Hematological and urine analyses did not reveal any alterations associated with PEA-m treatment, and no serious adverse events were reported. These results suggest that PEA-m could be considered as a promising and well-tolerated new treatment for symptomatology experienced by diabetic patients suffering from peripheral neuropathy. ","PeriodicalId":19786,"journal":{"name":"Pain Research and Treatment","volume":"2014 ","pages":"849623"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/849623","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32322575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 43

Effect of pregabalin and dexamethasone on postoperative analgesia after septoplasty. 普瑞巴林联合地塞米松对鼻中隔成形术术后镇痛的影响。

Pain Research and Treatment Pub Date : 2014-01-01 Epub Date: 2014-04-24 DOI: 10.1155/2014/850794

Abdullah Demirhan, Akcan Akkaya, Umit Yasar Tekelioglu, Tayfun Apuhan, Murat Bilgi, Veysel Yurttas, Hakan Bayir, Isa Yildiz, Uzeyir Gok, Hasan Kocoglu

{"title":"Effect of pregabalin and dexamethasone on postoperative analgesia after septoplasty.","authors":"Abdullah Demirhan, Akcan Akkaya, Umit Yasar Tekelioglu, Tayfun Apuhan, Murat Bilgi, Veysel Yurttas, Hakan Bayir, Isa Yildiz, Uzeyir Gok, Hasan Kocoglu","doi":"10.1155/2014/850794","DOIUrl":"https://doi.org/10.1155/2014/850794","url":null,"abstract":"Objectives. The aim of this study was to explore effect of a combination of pregabalin and dexamethasone on pain control after septoplasty operations. Methods. In this study, 90 patients who were scheduled for septoplasty under general anesthesia were randomly assigned into groups that received either placebo (Group C), pregabalin (Group P), or pregabalin and dexamethasone (Group PD). Preoperatively, patients received either pregabalin 300 mg one hour before surgery, dexamethasone 8 mg intravenously during induction, or placebo according to their allocation. Postoperative pain treatment included tramadol and diclofenac sodium 30 minutes before the end of the operation. Numeric rating scale (NRS) for pain assessment, side effects, and consumption of tramadol, pethidine, and ondansetron were recorded. Results. The median NRS score at the postoperative 0 and the 2nd h was significantly higher in Group C than in Group P and Group PD (P ≤ 0.004 for both). The 24 h tramadol and pethidine, consumptions were significantly reduced in Groups P and PD compared to Group C (P < 0.001 and P < 0.001). The incidence of blurred vision was significantly higher in Group PD compared to Group C within both 0-2 h and 0-24 h periods (P = 0.002 and P < 0.001, resp.). Conclusions. We conclude that administration of 300 mg pregabalin preoperatively may be an adequate choice for pain control after septoplasty. Addition of dexamethasone does not significantly reduce pain in these patients. ","PeriodicalId":19786,"journal":{"name":"Pain Research and Treatment","volume":"2014 ","pages":"850794"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/850794","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32382245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 30