Otology & Neurotology最新文献

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Treatment Response Evaluation in Necrotizing Otitis Externa Using 18 F-FDG-PET Imaging. 应用18F-FDG-PET显像评价坏死性外耳炎治疗效果。
IF 1.9 3区 医学
Otology & Neurotology Pub Date : 2025-03-01 Epub Date: 2025-01-09 DOI: 10.1097/MAO.0000000000004402
Robin W Jansen, Pieter Kemp, Sanne E Wiegers, Pim de Graaf, Annelies van Schie, Roland M Martens, Ronald Boellaard, Gerben J C Zwezerijnen, Thadé Goderie
{"title":"Treatment Response Evaluation in Necrotizing Otitis Externa Using 18 F-FDG-PET Imaging.","authors":"Robin W Jansen, Pieter Kemp, Sanne E Wiegers, Pim de Graaf, Annelies van Schie, Roland M Martens, Ronald Boellaard, Gerben J C Zwezerijnen, Thadé Goderie","doi":"10.1097/MAO.0000000000004402","DOIUrl":"10.1097/MAO.0000000000004402","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to identify 18 F-FDG-PET imaging features for improving treatment response evaluation in patients with necrotizing otitis externa (NOE), aiding in the difficult differentiation between sterile inflammation and active infection.</p><p><strong>Study design: </strong>Retrospective cohort study.</p><p><strong>Setting: </strong>Tertiary hospital.</p><p><strong>Patients: </strong>Patients diagnosed with NOE between 2011 and 2022. NOE criteria included otalgia, otorrhea, granulation, and radiological features consistent with osteomyelitis.</p><p><strong>Intervention: </strong>18 F-FDG-PET/computed tomography (CT) parameters were derived from manually delineated regions of interest and were evaluated on both pretreatment and end-of-treatment scans.</p><p><strong>Main outcome measures: </strong>Recurrent disease of NOE after end-of-treatment 18 F-FDG-PET scans.</p><p><strong>Results: </strong>This study comprised 20 NOE patients, including 5 (25%) experiencing recurrent disease after the end-of-treatment scan. The end-of-treatment 18 F-FDG-PET parameters of maximal and peak standardized uptake value (SUVmax and SUVpeak) were significantly higher in recurrent cases ( p = 0.025 and p = 0.025, respectively). Both parameters demonstrated good discrimination ability in predicting recurrence, with optimal cutoffs yielding 100% sensitivity and 67% specificity. Other parameters, including mean SUV and total lesion glycolysis (TLG), did not yield significant results, neither did the calculated difference in uptake between end-of-treatment and pretreatment scans.</p><p><strong>Conclusions: </strong>SUVpeak on 18 F-FDG-PET was the preferred parameter for treatment response evaluation of NOE at the end-of-treatment scan. A high residual SUVpeak may adequately detect patients at risk for recurrent disease, which may necessitate prolonged treatment, while low SUVpeak is found in patients with low risk for recurrent disease permitting safe treatment cessation.</p>","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":" ","pages":"295-302"},"PeriodicalIF":1.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142966399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hearing Preservation Outcomes in 230 Consecutive Patients with Small Vestibular Schwannomas Treated with Microsurgery. 230例连续小前庭神经鞘瘤显微手术治疗的听力保护效果。
IF 1.9 3区 医学
Otology & Neurotology Pub Date : 2025-03-01 Epub Date: 2025-01-09 DOI: 10.1097/MAO.0000000000004404
Pawina Jiramongkolchai, Alexandra Vacaru, Tamara Wahlin, Marc S Schwartz, Rick A Friedman
{"title":"Hearing Preservation Outcomes in 230 Consecutive Patients with Small Vestibular Schwannomas Treated with Microsurgery.","authors":"Pawina Jiramongkolchai, Alexandra Vacaru, Tamara Wahlin, Marc S Schwartz, Rick A Friedman","doi":"10.1097/MAO.0000000000004404","DOIUrl":"10.1097/MAO.0000000000004404","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate hearing preservation (HP) outcomes for patients with small sporadic vestibular schwannomas (VS) who elect to undergo microsurgical resection.</p><p><strong>Study design: </strong>Retrospective study.</p><p><strong>Setting: </strong>Tertiary single-academic institution.</p><p><strong>Patients: </strong>Individuals 18 years or older with small sporadic VS (≤15 mm) who underwent microsurgical resection from 2018 to 2023.</p><p><strong>Interventions: </strong>Microsurgical resection via a middle cranial fossa (MCF) or retrosigmoid (RS) approach.</p><p><strong>Main outcome measures: </strong>Postoperative HP (word recognition score ≥ 50%) and facial nerve function.</p><p><strong>Results: </strong>Of the 230 consecutive patients with small sporadic VS who elected to undergo microsurgical resection, hearing was preserved in 61% of patients. When stratified by tumor size, patients with tumors ≤10 mm had a 72% hearing preservation rate. On multivariate analysis, the most important prognostic factors for hearing preservation were the presence of preoperative vertigo (OR, 0.33; 95% CI, 0.17-0.52) and tumor size. Patients with tumors between 0 to 5 mm and 5.1 to 10 mm had 3.62 higher odds (95% CI, 1.39-9.4) and 2.52 higher odds (95% CI, 1.30-4.9) of hearing preservation, respectively, when compared to patients with tumors that were larger than 10 mm. At the time of last follow-up, a House-Brackmann (HB) 1 or 2 was maintained in 95% (n = 218) patients.</p><p><strong>Conclusions: </strong>Microsurgical resection for patients with small VS is associated with good hearing preservation and excellent facial nerve outcomes. Because larger tumor size portends poorer hearing outcomes, for patients who elect to undergo microsurgical resection for hearing preservation, proactive surgical intervention when tumors are ≤10 mm should be considered to increase the likelihood of hearing preservation.</p>","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":" ","pages":"303-307"},"PeriodicalIF":1.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142966398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Automated Technical Skill and Performance Assessment in Otology and Neurotology: A Scoping Review.
IF 1.9 3区 医学
Otology & Neurotology Pub Date : 2025-03-01 Epub Date: 2025-01-22 DOI: 10.1097/MAO.0000000000004427
Obinna I Nwosu, Mitsuki Ota, Deborah Goss, Matthew G Crowson
{"title":"Automated Technical Skill and Performance Assessment in Otology and Neurotology: A Scoping Review.","authors":"Obinna I Nwosu, Mitsuki Ota, Deborah Goss, Matthew G Crowson","doi":"10.1097/MAO.0000000000004427","DOIUrl":"https://doi.org/10.1097/MAO.0000000000004427","url":null,"abstract":"<p><strong>Objectives/hypothesis: </strong>This scoping review aims to provide an overview of existing semi-automated and fully automated methods for technical skill and performance assessment in otologic and neurotologic procedures.</p><p><strong>Study design: </strong>Scoping review.</p><p><strong>Databases reviewed: </strong>Ovid MEDLINE (PubMed), Ovid EMBASE, Web of Science Core Collection, and IEEE Xplor Digital Library.</p><p><strong>Methods: </strong>A literature search was conducted according to PRISMA-ScR. Included studies were full-text articles that detailed an automated method of technical skill and performance assessment in otologic/neurotologic procedures. Extracted elements included general study characteristics (publication year, study objective, validity type, surgical procedure, and setting) and assessment approach characteristics (method of analysis, metrics assessed, source of metric data, degree of automation, and use of artificial intelligence [AI]).</p><p><strong>Results: </strong>A total of 1,141 studies were identified from the literature search. After deduplication, title/abstract screening, and full-text review, 21 studies met the inclusion criteria. All but one of the included studies focused on mastoidectomy. Most studies assessed performance exclusively in VR-simulated mastoidectomy (n = 12) as opposed to cadaveric, 3D-printed, or live dissections. The majority of studies concentrated on establishing internal validity of their assessment methods (n = 13). Performance metrics were primarily obtained through motion analysis and final product analysis. Only a minority of studies used AI, which typically involved machine learning regression or classification to predict skill levels based on automatically extracted metrics.</p><p><strong>Conclusion: </strong>This scoping review explores the developing landscape of automated technical skill and performance assessment in otology and neurotology. Though progress has been made in automating assessment in the field, most investigations are narrowly focused on performance in VR-simulated mastoidectomy and lack external validity evidence. AI and computer vision (CV), which have advanced automated assessment in other surgical fields, have been underutilized in assessing performance in otology and neurotology. Future work must explore the development and validation of automated assessment approaches across a wider range of otologic and neurotologic procedures. Incorporation of novel AI/CV techniques may facilitate real-time integration of automated assessment in a broader range of simulated procedures and live surgical settings.</p>","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":"46 3","pages":"248-255"},"PeriodicalIF":1.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143416956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Insertion Depth and Modiolar Proximity on Cochlear Implant Speech Recognition Outcomes With a Precurved Electrode Array.
IF 1.9 3区 医学
Otology & Neurotology Pub Date : 2025-03-01 Epub Date: 2024-12-30 DOI: 10.1097/MAO.0000000000004405
Michael W Canfarotta, Margaret T Dillon, Nicholas J Thompson, A Morgan Selleck, Matthew M Dedmon, Kevin D Brown
{"title":"Effects of Insertion Depth and Modiolar Proximity on Cochlear Implant Speech Recognition Outcomes With a Precurved Electrode Array.","authors":"Michael W Canfarotta, Margaret T Dillon, Nicholas J Thompson, A Morgan Selleck, Matthew M Dedmon, Kevin D Brown","doi":"10.1097/MAO.0000000000004405","DOIUrl":"https://doi.org/10.1097/MAO.0000000000004405","url":null,"abstract":"<p><strong>Objectives: </strong>To examine the relationship between angular insertion depth (AID), modiolar proximity, and speech recognition outcomes for cochlear implant (CI) recipients of a precurved electrode array.</p><p><strong>Study design: </strong>Retrospective review.</p><p><strong>Setting: </strong>Tertiary academic referral center.</p><p><strong>Patients: </strong>Thirty-five adult CI recipients (n = 40 ears) of precurved electrode arrays listening with a CI-alone device.</p><p><strong>Interventions: </strong>Cochlear implantation with postoperative computed tomography.</p><p><strong>Main outcome measures: </strong>Consonant-nucleus-consonant (CNC) word recognition at 6 months post-activation.</p><p><strong>Results: </strong>A multivariate regression model demonstrated that both deeper apical AID and closer modiolar proximity in the basal turn were independently associated with better CNC word scores at 6 months (F2,37 = 7.264, p = 0.002). A deeper basal insertion depth was positively correlated with apical AID (r = 0.754, p < 0.001) but negatively correlated with modiolar proximity in the basal turn (r = -0.766, p < 0.001).</p><p><strong>Conclusions: </strong>These data suggest that both apical cochlear coverage and modiolar proximity independently confer speech recognition benefit with a precurved array. However, these benefits are mutually exclusive for current precurved array designs as a deeper basal insertion depth results in greater apical coverage but lateralization of electrodes away from the modiolus in the basal turn. Future work is needed to elucidate mechanisms behind these findings that may motivate electrode array design modifications to further optimize outcomes for CI users.</p>","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":"46 3","pages":"272-278"},"PeriodicalIF":1.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143416958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Possible Role of Biofilm Formation in Recidivism of Cholesteatomatous and Noncholesteatomatous Chronic Suppurative Otitis Media.
IF 1.9 3区 医学
Otology & Neurotology Pub Date : 2025-03-01 Epub Date: 2025-01-22 DOI: 10.1097/MAO.0000000000004424
Zuhal Zeybek Sivas, Nadir Yıldırım
{"title":"The Possible Role of Biofilm Formation in Recidivism of Cholesteatomatous and Noncholesteatomatous Chronic Suppurative Otitis Media.","authors":"Zuhal Zeybek Sivas, Nadir Yıldırım","doi":"10.1097/MAO.0000000000004424","DOIUrl":"https://doi.org/10.1097/MAO.0000000000004424","url":null,"abstract":"<p><strong>Objective: </strong>Chronic suppurative otitis media (CSOM) is typically classified into two distinct types: CSOM (without cholestetoma) and CSOM with cholesteatoma (CCSOM). The main microbial agents in both types are Pseudomonas aeruginosa, Staphylococcus aureus, and Klebsiella pneumoniae. It is believed that the virulence of the infecting microorganisms and their biofilm production capacity play a role in the chronicity and persistence of the disease. The aim of this study was to investigate the pathogen microorganisms with their biofilm formation in CSOM, CCSOM, and their recidivism.</p><p><strong>Materials and methods: </strong>A cohort of 57 patients was separated into four subgroups as primary CSOM (CSOM, CCSOM) and postoperatively recurring/residual CSOM [(R)CSOM, (R)CCSOM] groups. A control group was formed of 10 patients who underwent tympanotomy for conductive hearing loss without any known past/present ear inflammation. In all 67 patients, ear swabs for culture and the tissue samples for biofilm studies were obtained pre- or intraoperatively.</p><p><strong>Results: </strong>The most common bacteria grown in the culture mediums were Pseudomonas spp., S. aureus, coagulase-negative Staphylococcus, and coliform bacteria. In the SEM study, biofilms were detected in 9 of 15 CCSOM and 6 of 14 CSOM, and in 13 of 14 (R)CCSOM and 11 of 14 (R)CSOM ears. Statistical analysis showed significantly higher rates of biofilm formation in both recidivist cholesteatomatous and noncholesteatomatous CSOM groups than their primary counterpart groups.</p><p><strong>Conclusion: </strong>The findings that biofilm is more prevalent in the recidivist cases substantiated that biofilm formation is correlated with the persistence and additionally aggressiveness of the disease in both CSOM types. S. aureus appeared as the leading biofilm-producing bacterium.</p>","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":"46 3","pages":"e74-e80"},"PeriodicalIF":1.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143416970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Amplitude and Phase Changes in Electrocochleographic Real-Time Recordings During Cochlear Implantation and Its Relation to Pre- and Postoperative Hearing. 人工耳蜗植入过程中实时记录的振幅和相位变化及其与术前和术后听力的关系。
IF 1.9 3区 医学
Otology & Neurotology Pub Date : 2025-03-01 Epub Date: 2025-01-30 DOI: 10.1097/MAO.0000000000004420
Adrian Dalbert, Christofer Bester, Aaron Collins, Tayla Razmovski, Jean-Marc Gerard, Stephen O'Leary
{"title":"Amplitude and Phase Changes in Electrocochleographic Real-Time Recordings During Cochlear Implantation and Its Relation to Pre- and Postoperative Hearing.","authors":"Adrian Dalbert, Christofer Bester, Aaron Collins, Tayla Razmovski, Jean-Marc Gerard, Stephen O'Leary","doi":"10.1097/MAO.0000000000004420","DOIUrl":"10.1097/MAO.0000000000004420","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study was to relate response patterns of electrocochleography (ECochG) recordings during cochlear implantation to pre- and postoperative hearing.</p><p><strong>Methods: </strong>Thirty subjects with either flat (FA, n = 9) or sloping (SA, n = 21) audiograms before cochlear implantation were prospectively included. Real-time ECochG recordings were conducted via the cochlear implant. The difference curve (DIF) signal of the ECochG recordings was analyzed regarding alteration of the waveform, amplitude changes, and relative phase shifts during insertion.</p><p><strong>Results: </strong>Five subjects (56%) with FA and 13 (62%) with SA exhibited DIF signal drops in the early phase of the insertion. In subjects with FA, alterations of the DIF signal waveform in the early phase of the insertion occurred in 8 subjects (90%), whereas such changes were detectable in only 2 out of 21 subjects (10%) with SA ( p < 0.001). DIF signal drops with relative phase shifts of >0.7 radians but without alterations of the waveform occurred in 5 subjects (56%) with FA and 11 (52%) with SA. Such drops were associated with larger postoperative hearing losses than DIF signal drops without phase changes in both groups (FA: 43 versus 20 dB, p = 0.045; SA: 30 versus 14 dB, p = 0.001).</p><p><strong>Conclusion: </strong>Residual cochlear function in basal regions leads to alteration of the DIF signal waveform during insertion, probably not associated with cochlear injury. A decrease of the DIF signal amplitude with a simultaneous relative phase shift but no alteration of the waveform is associated with greater loss of residual hearing independent from the preoperative hearing.</p>","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":" ","pages":"e65-e73"},"PeriodicalIF":1.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142966395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hearing Preservation and Functional Outcomes After Resection of Epidermoid Lesions of the Cerebellopontine Angle With High Hearing Risk.
IF 1.9 3区 医学
Otology & Neurotology Pub Date : 2025-03-01 Epub Date: 2024-12-24 DOI: 10.1097/MAO.0000000000004408
Michael Papazian, Justin Cottrell, Jackie Yang, Emily Kay-Rivest, David R Friedmann, Daniel Jethanamest, Douglas Kondziolka, Donato Pacione, Chandranath Sen, John G Golfinos, J Thomas Roland, Sean O McMenomey
{"title":"Hearing Preservation and Functional Outcomes After Resection of Epidermoid Lesions of the Cerebellopontine Angle With High Hearing Risk.","authors":"Michael Papazian, Justin Cottrell, Jackie Yang, Emily Kay-Rivest, David R Friedmann, Daniel Jethanamest, Douglas Kondziolka, Donato Pacione, Chandranath Sen, John G Golfinos, J Thomas Roland, Sean O McMenomey","doi":"10.1097/MAO.0000000000004408","DOIUrl":"https://doi.org/10.1097/MAO.0000000000004408","url":null,"abstract":"<p><strong>Objectives: </strong>To assess a decade of experience of treating patients with high hearing risk cerebellopontine angle (CPA) epidermoid lesions and examine factors influencing postoperative outcomes, particularly hearing preservation.</p><p><strong>Study design: </strong>Retrospective chart review.</p><p><strong>Setting: </strong>Single tertiary-referral center.</p><p><strong>Patients: </strong>Adults with CPA epidermoid lesions who presented with hearing loss or evidence of lesion involving vestibulocochlear nerve.</p><p><strong>Interventions: </strong>The studied intervention was microsurgical resection.</p><p><strong>Main outcome measures: </strong>Main outcome measures included extent of resection, hearing preservation rate for patients with postoperative audiograms, and disease progression.</p><p><strong>Results: </strong>Twenty-three adults with an average tumor volume of 15.63 ± 16.2 cm3 were included. Five lesions (22%) involved the full internal auditory canal (IAC), 11 (48%) had partial involvement, and 5 (22%) were IAC sparing. Most patients with IAC involvement (88%) had circumferential invasion of the canal. Patients underwent either a retrosigmoid (18, 79%) or combined retrolabyrinthine transpetrosal approach (5, 22%), and gross total resection was achieved in most cases (13, 57%). Of 12 patients with postoperative audiograms, 10 (83%) had preoperative hearing preserved. There was no statistically significant change in hearing scores with treatment based on preoperative extent of IAC involvement. Ten patients (43%) had residual lesions postoperatively, and 6 exhibited progression. One patient ultimately required reoperation 6 years after initial surgery.</p><p><strong>Conclusions: </strong>Preoperative hearing was preserved in the majority of the patients who underwent resection of CPA epidermoids via a retrosigmoid or transpetrosal approach. CPA epidermoids often invaded the IAC; however, degree of invasion was not associated with hearing outcomes.</p>","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":"46 3","pages":"308-313"},"PeriodicalIF":1.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143416961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Music Combined with Cognitive Behavioral Therapy Enhanced Functional Integration within the Frontal-Parietal-Temporal Brain Network in Patients with Chronic Subjective Tinnitus.
IF 1.9 3区 医学
Otology & Neurotology Pub Date : 2025-03-01 Epub Date: 2024-12-18 DOI: 10.1097/MAO.0000000000004409
Yiwen Luo, Minqian Gao, Yongtao Xiao, Haidi Yang
{"title":"Music Combined with Cognitive Behavioral Therapy Enhanced Functional Integration within the Frontal-Parietal-Temporal Brain Network in Patients with Chronic Subjective Tinnitus.","authors":"Yiwen Luo, Minqian Gao, Yongtao Xiao, Haidi Yang","doi":"10.1097/MAO.0000000000004409","DOIUrl":"https://doi.org/10.1097/MAO.0000000000004409","url":null,"abstract":"<p><strong>Background: </strong>This study was aimed at investigating the effectiveness of music combined with cognitive behavioral therapy (music-CBT) and its underlying therapeutic mechanisms in treating chronic subjective tinnitus.</p><p><strong>Methods: </strong>Twenty-seven participants with chronic subjective tinnitus who underwent a 3-month music-CBT were initially involved in this retrospective study. The resting-state electroencephalograms (EEG) and behavioral assessments of pre- and post-music-CBT, including tinnitus handicap inventory (THI), tinnitus functional index (TFI), visual analog scales (VAS), Pittsburgh sleep quality index (PSQI), and Hamilton depression rating scale (HAMD-24) were collected and analyzed.</p><p><strong>Results: </strong>Following music-CBT, there was a significant reduction in global behavioral assessment scores, with median changes of ΔTHI = 26.0 (p < 0.001), ΔTFI = 23.7 (p < 0.001), ΔVAS = 2.0 (p < 0.001), ΔPSQI = 2.0 (p = 0.002), and ΔHAMD-24 = 2.0 (p < 0.001). Enhanced functional connectivity was seen among the frontal, parietal, and temporal cortices and significantly decreased characteristic path length (ΔCPL in delta = 0.016, p = 0.031; ΔCPL in theta = 0.012, p = 0.013), increased global efficiency (ΔGE in delta = -0.014, p = 0.037; ΔGE in theta = -0.006, p = 0.021), and local efficiency (ΔLE in delta = -0.015, p = 0.037; ΔLE in theta = -0.012, p = 0.015) were also noted. Additionally, associations were identified between ΔPSQI and ΔTHI (rho = 0.546, p = 0.003) and ΔTFI (rho = 0.462, p = 0.015); between ΔHAMD-24 and ΔCPL (rho = -0.389, p = 0.045), ΔGE (rho = 0.395, p = 0.041), and ΔLE (rho = 0.405, p = 0.036).</p><p><strong>Conclusion: </strong>Optimized cognitive and emotional responses to tinnitus are linked to functional integration within the frontal-parietal-temporal brain network. Early node indicators for tinnitus relief may be the precuneus, middle frontal gyrus, middle temporal gyrus, and the right inferior parietal lobule.</p>","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":"46 3","pages":"e56-e64"},"PeriodicalIF":1.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143416964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Access to Ear and Hearing Care Globally: A Survey of Stakeholder Perceptions from the Lancet Commission on Global Hearing Loss. 全球获得耳科和听力保健的机会:柳叶刀全球听力损失委员会利益相关者看法调查》。
IF 1.9 3区 医学
Otology & Neurotology Pub Date : 2025-03-01 DOI: 10.1097/MAO.0000000000004401
Rolvix H Patterson, Catherine McMahon, Chris Waterworth, Sarah Morton, Alyssa Platt, Shelly Chadha, Mary Jue Xu, Carolina Der, Doreen Nakku, Amina Seguya, Robert Frost, Ali Jaffer, Samantha Kleindienst Robler, Susan D Emmett
{"title":"Access to Ear and Hearing Care Globally: A Survey of Stakeholder Perceptions from the Lancet Commission on Global Hearing Loss.","authors":"Rolvix H Patterson, Catherine McMahon, Chris Waterworth, Sarah Morton, Alyssa Platt, Shelly Chadha, Mary Jue Xu, Carolina Der, Doreen Nakku, Amina Seguya, Robert Frost, Ali Jaffer, Samantha Kleindienst Robler, Susan D Emmett","doi":"10.1097/MAO.0000000000004401","DOIUrl":"10.1097/MAO.0000000000004401","url":null,"abstract":"<p><strong>Objective: </strong>Characterize global access to ear and hearing care (EHC) to inform future policy recommendations.</p><p><strong>Study design: </strong>Survey using convenience sampling.</p><p><strong>Setting: </strong>Subjects were surveyed via contact lists of the World Health Organization, Global Otolaryngology-Head and Neck Surgery Initiative, and Global HEAR Collaborative.</p><p><strong>Participants: </strong>Otolaryngologists, audiologists, other health care professionals, adults with hearing loss, parents/caregivers of children with hearing loss, and policymakers.</p><p><strong>Intervention: </strong>None.</p><p><strong>Main outcome and measures: </strong>Responses to questions regarding EHC screening programs, workforce, supports, access to care, and government priority by World Bank income group.</p><p><strong>Results: </strong>There were 125 included survey responses from EHC stakeholders representing 59 countries: 71% from low- and middle-income countries (LMICs) and 29% from high-income countries (HICs). Compared with respondents from LMICs, those from HICs more frequently indicated that their country had adequate numbers of ENTs, audiologists, SLPs, and EHC community health workers. This trend was consistent across questions regarding number of training programs for EHC workforce, presence of hearing screening programs, cost of hearing aids and cochlear implants, availability of EHC supports and services, affordability of EHC, government funding or investment, and inclusion of EHC in national health strategy.</p><p><strong>Conclusion: </strong>Globally, EHC is limited by systems-level barriers that disproportionately affect LMICs. Urgent policy development and intervention is needed to eliminate these barriers and improve EHC around the world.</p>","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":"46 3","pages":"256-264"},"PeriodicalIF":1.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143416947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Degree of Preoperative Bilateral Hearing Affects Patient-Reported Outcome in Primary Stapedotomy. 术前双侧听力程度影响初次镫骨切除术患者报告的预后。
IF 1.9 3区 医学
Otology & Neurotology Pub Date : 2025-03-01 Epub Date: 2025-01-07 DOI: 10.1097/MAO.0000000000004413
Ulrica Thunberg, Taj Tahir, Ylva Dahlin Redfors, Caterina Finizia
{"title":"Degree of Preoperative Bilateral Hearing Affects Patient-Reported Outcome in Primary Stapedotomy.","authors":"Ulrica Thunberg, Taj Tahir, Ylva Dahlin Redfors, Caterina Finizia","doi":"10.1097/MAO.0000000000004413","DOIUrl":"10.1097/MAO.0000000000004413","url":null,"abstract":"<p><strong>Objective: </strong>To investigate whether degree of asymmetric hearing impairment influences patient-reported outcome measures and objective hearing results in primary stapedotomy.</p><p><strong>Study design: </strong>Register study.</p><p><strong>Setting: </strong>Data from the Swedish Quality Register for Otosclerosis Surgery consisting of 90% of stapes operations performed in Sweden.</p><p><strong>Main outcome measure: </strong>The 984 patients eligible for inclusion were categorized on the basis of preoperative hearing impairment: unilateral, bilateral asymmetric, or bilateral symmetric. Pure-tone audiometry and patient-reported outcome measures were analyzed, and Glasgow benefit plots were constructed. Ordinal logistics regression analyses were performed to adjust for factors influencing PROMs associated with degree of asymmetric hearing.</p><p><strong>Results: </strong>Over 90% of patients across all groups reported improved or much improved hearing ability post-surgery. Ninety-five percent of patients who rated their hearing as worse or much worse after surgery had an air-conductive gain of <20 dB PTA4. Individuals with unilateral hearing impairment were more likely to report lower satisfaction with hearing function and daily life activities after surgery compared with those with bilateral hearing impairment, especially bilateral symmetric hearing impairment. In terms of hearing function, the bilateral symmetric hearing impairment group showed a significant decrease in the log odds of reporting lower satisfaction with a coefficient of -0.71 (95% confidence interval, -1.13 to -0.33), whereas the bilateral asymmetric hearing impairment group showed a nonsignificant decrease with a coefficient of -0.14 (95% confidence interval, -0.41 to 0.14) compared with the unilateral hearing impairment group. Tinnitus was more frequent in those with unilateral hearing impairment.</p><p><strong>Conclusion: </strong>Those with preoperative unilateral hearing impairment were more likely to express lower satisfaction with the results, compared with patients with bilateral impairment. Our findings suggest that the degree of bilateral hearing impairment should be considered in preoperative counseling, to better align with patient expectations regarding the benefit of surgery. An estimated air-conductive gain of at least 20 dB PTA4 was favorable for patient satisfaction.</p>","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":" ","pages":"265-271"},"PeriodicalIF":1.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142966397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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