Otology & Neurotology最新文献

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Infection in Pediatric Auditory Brainstem Implant: A Case Study and Scoping Review. 儿童听性脑干植入物感染:个案研究及范围回顾。
IF 1.7 3区 医学
Otology & Neurotology Pub Date : 2026-10-19 DOI: 10.1097/MAO.0000000000005100
Leena Asfour, Aparna Govindan, John M Reynolds, Sandra Velandia, Fred Telischi, Carolina Benjamin, Christine T Dinh
{"title":"Infection in Pediatric Auditory Brainstem Implant: A Case Study and Scoping Review.","authors":"Leena Asfour, Aparna Govindan, John M Reynolds, Sandra Velandia, Fred Telischi, Carolina Benjamin, Christine T Dinh","doi":"10.1097/MAO.0000000000005100","DOIUrl":"https://doi.org/10.1097/MAO.0000000000005100","url":null,"abstract":"<p><strong>Objective: </strong>Safety and efficacy of pediatric auditory brainstem implants (ABI) are well established. Commonly reported complications include cerebrospinal fluid (CSF) leak and pseudomeningocele. Infection is rare but potentially serious due to intracranial location of the device. Data on pediatric ABI infections remain limited. We report a case of pediatric ABI infection and perform a scoping review of the literature.</p><p><strong>Databases reviewed: </strong>PubMed, Web of Science, Scopus, and the Cochrane Library.</p><p><strong>Methods: </strong>The patient's medical record was reviewed for clinical course and outcomes. A scoping review was conducted to summarize findings of studies reporting pediatric ABI-related infections.</p><p><strong>Results: </strong>A 12-year-old female with NF2-related schwannomatosis and bilateral vestibular schwannomas underwent urgent right tumor resection with ABI placement. She represented on postoperative day 13 with meningitis and collection surrounding the device. Surgical exploration revealed purulence involving the ABI pocket and paddle. Device preservation was achieved with washout, fat graft replacement, vancomycin powder application, and prolonged antibiotic therapy. For the scoping review, 961 studies were screened and 9 included, identifying 12 pediatric ABI infections. Five were managed with antibiotics alone, 3 required additional CSF diversion, and 4 necessitated surgical intervention.</p><p><strong>Conclusion: </strong>Pediatric ABI infections are uncommon but potentially life-threatening, necessitating prompt recognition and aggressive management. Our scoping review revealed that pediatric ABI infections have been managed with antibiotics with or without surgical intervention, and infection-related ABI explantation in pediatric patients has not been reported. In our case, device preservation was achieved with washout, fat graft replacement, and intravenous and intrathecal antibiotics.</p>","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149224579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cost-Effectiveness of Intraoperative Facial Nerve Monitoring in Otologic Surgery. 耳科手术术中面神经监测的成本-效果。
IF 1.7 3区 医学
Otology & Neurotology Pub Date : 2026-10-19 DOI: 10.1097/MAO.0000000000005102
Sammy Y Gao, Warren B Chun, Tyler M Rist, Robert F Labadie
{"title":"Cost-Effectiveness of Intraoperative Facial Nerve Monitoring in Otologic Surgery.","authors":"Sammy Y Gao, Warren B Chun, Tyler M Rist, Robert F Labadie","doi":"10.1097/MAO.0000000000005102","DOIUrl":"https://doi.org/10.1097/MAO.0000000000005102","url":null,"abstract":"<p><strong>Objective: </strong>Evaluate the cost-effectiveness of intraoperative facial nerve monitoring (FNM) during otologic/neurotologic surgery.</p><p><strong>Study design: </strong>Decision-tree cost-effectiveness analysis with probabilistic sensitivity analysis using 1000-iteration Monte Carlo simulation.</p><p><strong>Setting: </strong>Tertiary academic center.</p><p><strong>Patients: </strong>Hypothetical adult cohort undergoing otologic surgery.</p><p><strong>Interventions: </strong>FNM for all otologic surgeries, FNM for revision surgeries only, and no FNM.</p><p><strong>Main outcome measures: </strong>Expected quality-adjusted life years (QALYs), expected cost per patient, incremental cost-effectiveness ratio (ICER; difference in cost/difference in QALY), and probability of cost-effectiveness at willingness-to-pay thresholds.</p><p><strong>Results: </strong>FNM for all otologic surgeries (both primary and revision) was associated with an increase in QALYs of 0.18 compared with no monitoring. Average cost increased by $169.99 per patient for equipment purchased from vendor 1 (ICER=$968.21/QALY), by $58.99 with vendor 2 (ICER=$336.00/QALY), and by $6.99 with vendor 3 (ICER=$39.83/QALY). Probabilistic sensitivity analysis demonstrated that monitoring all otologic surgeries was the most cost-effective strategy in most simulations (93% for vendor 1, 96% for vendor 2, and 95% for vendor 3) at a $50,000/QALY willingness-to-pay threshold. Sensitivity analysis suggested FNM to be cost-effective over a wide range of costs and probabilities.</p><p><strong>Conclusions: </strong>FNM for otologic surgery is cost-effective across vendors. Although use of higher-cost electrodes leads to increases in per-patient cost, the incremental cost per QALY gained remains minimal and well below accepted thresholds. These findings suggest routine FNM use in all cases is cost-effective, particularly in institutions with surgical volume to exceed break-even thresholds.</p>","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149224582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Safety-Net Hospitals Have Increased Costs of Care Following Acoustic Neuroma Surgery. 安全网医院增加了听神经瘤手术后的护理费用。
IF 1.7 3区 医学
Otology & Neurotology Pub Date : 2026-10-19 DOI: 10.1097/MAO.0000000000005101
Amor Niksic, Dakota Lipps, Hitomi Sakano, Daniel Killeen, Joe Walter Kutz, Brandon Isaacson, Rance J T Fujiwara
{"title":"Safety-Net Hospitals Have Increased Costs of Care Following Acoustic Neuroma Surgery.","authors":"Amor Niksic, Dakota Lipps, Hitomi Sakano, Daniel Killeen, Joe Walter Kutz, Brandon Isaacson, Rance J T Fujiwara","doi":"10.1097/MAO.0000000000005101","DOIUrl":"https://doi.org/10.1097/MAO.0000000000005101","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate whether safety-net hospital (SNH) status is associated with differences in patient characteristics, postoperative complications, and hospitalization costs following acoustic neuroma resection.</p><p><strong>Study design: </strong>Retrospective analysis of a nationally representative inpatient database.</p><p><strong>Setting: </strong>United States acute care hospitals participating in the Healthcare Cost and Utilization Project National Inpatient Sample (NIS).</p><p><strong>Patients: </strong>Adults (18 y or older) undergoing surgical excision of an acoustic neuroma from 2001 to 2021, identified using ICD-9-CM 04.01 and ICD-10-PCS 00BN0ZZ. Patients with neurofibromatosis type 2 were excluded.</p><p><strong>Interventions: </strong>Craniotomy for excision of acoustic neuroma.</p><p><strong>Main outcome measures: </strong>Postoperative surgical/CNS and medical complications; total inpatient hospitalization costs.</p><p><strong>Results: </strong>The cohort included 50,991 admissions, of which 13,245 (26.0%) occurred at SNHs. SNH patients were more likely to have Medicaid insurance (8.9% vs. 4.2%) and lower household income. On univariate analysis, SNHs had higher rates of hydrocephalus (6.0% vs. 3.8%), dysphagia (4.3% vs. 2.2%), pulmonary edema (2.1% vs. 1.1%), and sepsis (0.9% vs. 0.2%). After multivariable adjustment, SNH care remained independently associated with increased odds of medical complications (OR: 1.30; 95% CI: 1.01-1.70; P=0.04) but not surgical/CNS complications (OR: 1.10; P=0.23). Mean hospitalization costs were higher in SNHs ($42,749 vs. $36,456; P=0.003), and SNH status independently increased costs by $35,679 per admission (P=0.02).</p><p><strong>Conclusions: </strong>SNHs care for socioeconomically vulnerable patients undergoing acoustic neuroma resection and experience higher medical complication rates and significantly increased hospitalization costs. These findings highlight the need for resource-informed policy efforts and targeted support to sustain equitable access to complex neurotologic surgery.</p><p><strong>Level of evidence: </strong>Level III.</p>","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149224618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of Sociodemographic and Clinical Factors on Follow-up Adherence and Outcomes Following Bone-anchored Hearing Implantation. 社会人口学和临床因素对骨锚定助听器植入后随访依从性和结果的影响。
IF 1.7 3区 医学
Otology & Neurotology Pub Date : 2026-10-19 DOI: 10.1097/MAO.0000000000005097
Hannah Sturm, Alexis H Kim, Ivie Odia, Sarah Van der Elst, Stanley Pelosi, Andrea Vambutas, Maja Svrakic
{"title":"Influence of Sociodemographic and Clinical Factors on Follow-up Adherence and Outcomes Following Bone-anchored Hearing Implantation.","authors":"Hannah Sturm, Alexis H Kim, Ivie Odia, Sarah Van der Elst, Stanley Pelosi, Andrea Vambutas, Maja Svrakic","doi":"10.1097/MAO.0000000000005097","DOIUrl":"https://doi.org/10.1097/MAO.0000000000005097","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the relationship between sociodemographic and clinical factors and follow-up rates and outcomes after Osseointegrated Steady-State Implant (OSIA) implantation.</p><p><strong>Design: </strong>Retrospective cohort study.</p><p><strong>Setting: </strong>Tertiary care center.</p><p><strong>Patients: </strong>Individuals who underwent OSIA implantation at Northwell Health from September 24, 2020 to October 14, 2024.</p><p><strong>Intervention: </strong>Independent variables included race, language, insurance, income, hearing loss etiology and type, incision type, device model, and history of otologic surgery.</p><p><strong>Main outcomes: </strong>Dependent variables were audiologic and otologic follow-up adherence, time to surgery, time to activation (TTA), device use, surgical complications, and audiometric outcomes. Providers were also surveyed regarding perceived sociodemographic barriers to follow-up.</p><p><strong>Results: </strong>Fifty-nine patients (71 ears) were included. Patients from low-income areas had shorter time to surgery (9.2 vs. 24.2 mo, P = 0.044) but required more replacement parts (66.7% vs. 18.9%, P = 0.024). Medicaid-insured patients had longer TTA (59.6 vs. 43.8 d, P = 0.032). No other socioeconomic differences were significant. Congenital hearing loss correlated with fewer otology follow-ups (1.83 vs. 3.41, P = 0.0022), and conductive loss with more missed appointments (0.40 vs. 0.07, P = 0.026). Horizontal incisions were associated with fewer otologic follow-ups (1.89 vs. 3.74, P = 0.0023) and fewer replacements (13.9% vs. 39.1%, P = 0.033). OSI300 devices were activated sooner (43.3 vs. 56.9 d, P = 0.041) and required fewer otologic and audiologic follow-ups. Among 7 providers, 43% cited socioeconomic status, language, and insurance as barriers to follow-up; 14% cited race.</p><p><strong>Conclusions: </strong>Surgical timing, follow-up, and postoperative outcomes following OSIA implantation were driven primarily by clinical factors; among sociodemographic variables, only insurance type was associated with prolonged TTA. Provider perceptions overestimated the impact of sociodemographic factors.</p>","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149224588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mastoid Obliteration in Acquired Cholesteatoma, Importance and Evolution of Surgical Technique Used in Epitympanic Separation of the Middle Ear. 后天性胆脂瘤的乳突封堵术,中耳上鼓膜分离手术技术的重要性与发展。
IF 1.7 3区 医学
Otology & Neurotology Pub Date : 2026-10-16 DOI: 10.1097/MAO.0000000000005096
Alejandro Sutter, Maura C Eggink, Fenna A Ebbens, Maarten J F de Wolf, Erik van Spronsen
{"title":"Mastoid Obliteration in Acquired Cholesteatoma, Importance and Evolution of Surgical Technique Used in Epitympanic Separation of the Middle Ear.","authors":"Alejandro Sutter, Maura C Eggink, Fenna A Ebbens, Maarten J F de Wolf, Erik van Spronsen","doi":"10.1097/MAO.0000000000005096","DOIUrl":"https://doi.org/10.1097/MAO.0000000000005096","url":null,"abstract":"<p><strong>Objective: </strong>To determine the effect of the obliteration technique applied to divide the epitympanum from the middle ear during cholesteatoma surgery on the recurrence of cholesteatoma.</p><p><strong>Study design: </strong>Retrospective cohort study in a tertiary referral center.</p><p><strong>Patients: </strong>All patients undergoing cholesteatoma surgery from 2010 until 2023 were included. 116 pediatric cases, 286 adults. One hundred forty-two were primary surgeries, 260 revision procedures.</p><p><strong>Intervention: </strong>Canal wall up mastoidectomy and obliteration of the epitympanum and mastoid using different techniques.</p><p><strong>Main outcome measures: </strong>Recurrence rates and timing of recurrence during follow-up.</p><p><strong>Results: </strong>The overall recurrence rate was 11.69% (median FU 4.3 y, range: 0.02 to 12 y). The recurrence rates differed significantly among the 5 different techniques of obliteration: 100% after obliteration with bone pâté (median FU 3.3 y), 21% after a hybrid technique (median FU 2.5 y), 18% after cartilage (median FU 5.6 y), 10% after midtemporal artery flap (MTF, median FU 4.7 y), and 0% after an avital flap (median FU 0.6 y, range up to 11 y). When correcting for FU length, the statistically significant difference persisted in the Kaplan-Meier survival curves.</p><p><strong>Conclusions: </strong>To lower recurrence rates in canal wall up surgery with obliteration, the focus should lie in creating a complete and smooth separation of the middle ear from the epitympanum. Currently, the most favorable results are found when this separation is created with a vital MTF or an avital flap, followed by hydroxyapatite to fill up the rest of the epitympanic space and mastoid. This effect is independent of possible confounders such as age of the patient and different surgeons. The short FU for the current technique is a limitation; longer FU is needed to reliably confirm whether it reduces recurrent disease more effectively than previous techniques.</p>","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149207608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sweep Frequency Impedance Measures of Otosclerosis. 耳硬化的扫描频率阻抗测量。
IF 1.7 3区 医学
Otology & Neurotology Pub Date : 2026-10-16 DOI: 10.1097/MAO.0000000000005032
Hisashi Sugimoto, Teruki Toya, Yasunori Donjo, Ryosei Motoo, Manabu Inaba, Goki Nagasaki, Tomokazu Yoshizaki, Michio Murakoshi
{"title":"Sweep Frequency Impedance Measures of Otosclerosis.","authors":"Hisashi Sugimoto, Teruki Toya, Yasunori Donjo, Ryosei Motoo, Manabu Inaba, Goki Nagasaki, Tomokazu Yoshizaki, Michio Murakoshi","doi":"10.1097/MAO.0000000000005032","DOIUrl":"https://doi.org/10.1097/MAO.0000000000005032","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to validate the preoperative diagnosis of otosclerosis using a Sweep Frequency Impedance (SFI) meter. In addition, it investigated whether the measurement values obtained from the SFI meter correlate with the perceived stiffness of the stapes footplate.</p><p><strong>Study design: </strong>Retrospective cohort study.</p><p><strong>Setting: </strong>A tertiary referral center.</p><p><strong>Patients: </strong>Thirty-seven ears were surgically confirmed between September 2020 and December 2023 at Kanazawa University Hospital and affiliated institutions-22 diagnosed with otosclerosis and 15 with ossicular discontinuity.</p><p><strong>Interventions: </strong>(1) The diagnostic performance of SFI, tympanometry, the Carhart notch, and CT demineralization imaging. (2) Evaluation of the correlation between stapes footplate stiffness and SFI meter parameters, specifically the change in sound pressure level (ΔSPL) and the resonance frequency (RF).</p><p><strong>Main outcome measures: </strong>Correct diagnosis rate of SFI. Correlation between preoperative audiometric data and SFI meter parameters (ΔSPL and RF). Correlation between preoperative hearing data and the perceived stiffness of the stapes footplate.</p><p><strong>Results: </strong>The SFI meter demonstrated the highest diagnostic accuracy, with a correct diagnosis rate of 0.91, followed by the Carhart notch at 0.73 and CT imaging and tympanometry at 0.459. No statistically significant correlations were observed between preoperative audiometric data and SFI meter parameters or the perceived stiffness of the stapes footplate.</p><p><strong>Conclusions: </strong>The findings suggest that the SFI meter may provide superior diagnostic accuracy compared with conventional testing modalities. Although no statistically significant correlations were identified, the direction of the observed associations was consistent with the expected biomechanical model, in which increased stiffness would be associated with higher resonance frequency, reduced SPL modulation, and a larger AB gap. SFI measurements may offer a means to estimate the degree of stapes footplate fixation preoperatively.</p>","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149207562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cochlear Implantation and Cognitive Function in Adults: A Systematic Review and Meta-analysis. 成人人工耳蜗植入与认知功能:一项系统综述和荟萃分析。
IF 1.7 3区 医学
Otology & Neurotology Pub Date : 2026-10-16 DOI: 10.1097/MAO.0000000000005085
Christi A Joyce, Kelly Zhang, Joost J A Stultiens, Kelsey A Kidd, Alexandra E Quimby
{"title":"Cochlear Implantation and Cognitive Function in Adults: A Systematic Review and Meta-analysis.","authors":"Christi A Joyce, Kelly Zhang, Joost J A Stultiens, Kelsey A Kidd, Alexandra E Quimby","doi":"10.1097/MAO.0000000000005085","DOIUrl":"https://doi.org/10.1097/MAO.0000000000005085","url":null,"abstract":"<p><strong>Objective: </strong>To assess for changes in cognitive function in the first year following cochlear implantation in adult implant recipients.</p><p><strong>Database reviewed: </strong>MEDLINE, Embase, Cochrane CENTRAL, Web of Science, PsycINFO, and CINAHL.</p><p><strong>Methods: </strong>A comprehensive literature search was conducted to identify studies that assessed cognition in adult cochlear implant recipients. Included studies were English-language publications reporting objective cognitive testing scores both before and a minimum of 6 months after cochlear implantation in adults with postlingual hearing loss. Interventional studies, cohorts, case-controls, and case series with more than 5 patients were eligible. Two reviewers independently screened studies and extracted data. Study quality and risk of bias were evaluated using Newcastle-Ottawa Scale. Within-subjects random-effects meta-analyses were performed using the DerSimonian-Laird method. Pooled mean differences in cognitive test scores pre- versus postcochlear implantation were calculated for cognitive tests reported by more than 3 studies. Pooled standardized mean differences were calculated, including all reported cognitive tests across all studies.</p><p><strong>Results: </strong>Twenty eligible studies were identified, including a total of 798 cochlear implant recipients. Fifteen separate cognitive tests or testing batteries were applied at a median of 12 months postoperatively (range, 6 to 48 mo). The Mini-Mental Status Exam (MMSE) was the most frequently applied test (6 studies), followed by the MoCA (4 studies). Meta-analysis of mean differences showed no significant effect of cochlear implantation on MMSE score (pooled mean difference, 0.63 [95% CI: -1.02-2.28]), and a small but significant effect of cochlear implantation on MoCA score (pooled mean difference, 1.38 [95% CI: 0.33-2.42]). Considering all cognitive tests, there was a small but significant improvement in cognitive testing scores following cochlear implantation (pooled standardized mean difference 0.32 [95% CI: 0.19-0.44]).</p><p><strong>Conclusions: </strong>Cochlear implantation in adults is associated with small but significant improvements in cognitive testing scores on at least some tests. Further research is needed to assess whether these findings translate to a reduction in dementia risk.</p>","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149207449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optimizing Cochlear Implant Outcomes in Cochlear Nerve Aplasia: The EMPES Protocol (Early Implantation, Modiolar Proximity, and Early Switch-On). 优化人工耳蜗神经发育不全患者的人工耳蜗植入效果:EMPES方案(早期植入、模牙接近和早期开启)。
IF 1.7 3区 医学
Otology & Neurotology Pub Date : 2026-10-14 DOI: 10.1097/MAO.0000000000005065
Suji Jeong, Yehree Kim, Hyun Seong Kim, Seung Jae Lee, Heonjeong Oh, Hye-Rim Park, Ye Jun Cheon, Jun Ho Lee, Seung Ha Oh, Bong Jik Kim, Byung Yoon Choi
{"title":"Optimizing Cochlear Implant Outcomes in Cochlear Nerve Aplasia: The EMPES Protocol (Early Implantation, Modiolar Proximity, and Early Switch-On).","authors":"Suji Jeong, Yehree Kim, Hyun Seong Kim, Seung Jae Lee, Heonjeong Oh, Hye-Rim Park, Ye Jun Cheon, Jun Ho Lee, Seung Ha Oh, Bong Jik Kim, Byung Yoon Choi","doi":"10.1097/MAO.0000000000005065","DOIUrl":"https://doi.org/10.1097/MAO.0000000000005065","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the efficacy of EMPES [Early implantation, Modiolar Proximity (MP), and Early Switch-on] approach in bilateral cochlear nerve (CN) aplasia.</p><p><strong>Study design: </strong>Retrospective cohort study.</p><p><strong>Setting: </strong>Tertiary referral center.</p><p><strong>Patients: </strong>Forty-six children (86 ears) with bilateral CN aplasia underwent cochlear implantation (CI) between 2011 and 2024 at 2 tertiary centers.</p><p><strong>Intervention: </strong>For electrophysiological comparison, CI was performed using CI24RE-CA electrodes without pull-back (conventional implantation) or a slim modiolar electrode with pull-back (better MP). For speech outcome comparison, the conventional approach group comprised conventional implantation cases with ≥12-month follow-up, and the EMPES approach group comprised those in the better MP group implanted before 12 months and followed for ≥12 months.</p><p><strong>Main outcome measures: </strong>Mechanistic endpoint, intraoperative ECAP positivity; functional endpoint: longitudinal Categories of Auditory Performance (CAP) scores up to 48 months.</p><p><strong>Results: </strong>The better MP group showed higher intraoperative ECAP positivity, which translated into better postoperative outcomes. The EMPES approach demonstrated clear superiority in auditory performance up to 12 months [CAP score 3.00 (2.00 to 4.00) vs. 1.50 (1.00 to 2.25); P=0.010], with significantly fewer poor responders (CAP<2) at 1 year, and maintained narrower variability in median CAP scores through 36 months, indicating more stable auditory progress compared with the conventional approach. No clear association was observed between MRI-based CN aplasia severity and either ECAP positivity or audiological outcomes.</p><p><strong>Conclusions: </strong>The EMPES approach improves postoperative audiological outcomes during critical language periods and is recommended for bilateral CN aplasia to enhance language development and potentially reduce the need for auditory brainstem implantation.</p>","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149183352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comment to Study by Hol et al. 对Hol等人研究的评论。
IF 1.7 3区 医学
Otology & Neurotology Pub Date : 2026-10-13 DOI: 10.1097/MAO.0000000000004900
Ad Snik
{"title":"Comment to Study by Hol et al.","authors":"Ad Snik","doi":"10.1097/MAO.0000000000004900","DOIUrl":"10.1097/MAO.0000000000004900","url":null,"abstract":"","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148331968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Prospective, Multicenter Clinical Investigation on the Safety and Performance of a New Active Transcutaneous Bone-anchored Implant System. 一种新型主动经皮骨锚定植入系统安全性和性能的前瞻性多中心临床研究。
IF 1.7 3区 医学
Otology & Neurotology Pub Date : 2026-10-13 DOI: 10.1097/MAO.0000000000005080
Myrthe K S Hol, Tjerk W Aukema, Sander W J Ubbink, Dennis Lindholm, Marcus Holmberg, Susan Arndt, Stefanie Wolf, Peter Monksfield, Mihalache Marwa, Thomas Lenarz, Susan Busch, James Tysome, Abi Asher, Herman Kok, Emmanuel A M Mylanus
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