Otology & NeurotologyPub Date : 2025-06-01Epub Date: 2025-03-10DOI: 10.1097/MAO.0000000000004488
Masaya Uchida, Yu Matsumoto, Shigefumi Morioka, Ryusuke Hori, Kunio Mizutari
{"title":"Efficacy of Image-Guided Percutaneous Endoscopic Ear Surgery: A Novel Augmented Reality-Assisted Minimally Invasive Surgery.","authors":"Masaya Uchida, Yu Matsumoto, Shigefumi Morioka, Ryusuke Hori, Kunio Mizutari","doi":"10.1097/MAO.0000000000004488","DOIUrl":"10.1097/MAO.0000000000004488","url":null,"abstract":"<p><strong>Objective: </strong>Although transcanal endoscopic ear surgery (TEES) offers benefits of minimal invasion, it is difficult to access certain regions of the temporal bone, often necessitating a switch to more invasive methods, such as mastoidectomy. To overcome these challenges, we developed \"image-guided percutaneous endoscopic ear surgery (IGPEES),\" a novel technique designed to enhance the precision and safety of ear operations by integrating augmented reality (AR) and advanced navigation systems, allowing precise, minimally invasive access to the mastoid antrum and other difficult-to-reach areas. This study aimed to evaluate the efficacy and safety of IGPEES through a retrospective analysis of 11 cases.</p><p><strong>Study design: </strong>Retrospective analysis.</p><p><strong>Setting: </strong>Tertiary referral center.</p><p><strong>Main outcome measures: </strong>We analyzed the setup time and accuracy for navigation and complication rates of IGPEES.</p><p><strong>Results: </strong>Our results demonstrated that IGPEES reduced setup time and enhanced navigation accuracy compared with conventional surgical navigation systems, with no postoperative complications observed, thereby representing a promising advancement in otologic surgery.</p><p><strong>Conclusion: </strong>The integration of AR into IGPEES facilitates better surgical visualization and precision, potentially transforming standard practices for treating complex ear conditions.</p>","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":" ","pages":"532-538"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143616630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Otology & NeurotologyPub Date : 2025-06-01Epub Date: 2025-02-25DOI: 10.1097/MAO.0000000000004471
Andreas Radeloff, Katrin Radeloff, Rolf-Peter Henke, Sarah Hahnke, Maureen Loewenthal
{"title":"Cholesterol Granuloma Mimicking CSF Otorrhea by beta-Trace-Protein Production.","authors":"Andreas Radeloff, Katrin Radeloff, Rolf-Peter Henke, Sarah Hahnke, Maureen Loewenthal","doi":"10.1097/MAO.0000000000004471","DOIUrl":"10.1097/MAO.0000000000004471","url":null,"abstract":"<p><strong>Objective: </strong>To report a patient who was misdiagnosed and operated on for cerebrospinal fluid (CSF) otorrhea and to demonstrate that cholesterol granulomas mimic CSF leakage by secreting beta-trace protein (BTP).</p><p><strong>Patients: </strong>Eleven consecutive patients undergoing ear surgery in whom cholesterol granulomas were discovered intraoperatively.</p><p><strong>Intervention: </strong>Biochemical and histologic analysis of liquid and solid fractions of cholesterol granulomas.</p><p><strong>Main outcome measures: </strong>BTP and beta-2-transferrin concentrations and BTP mRNA levels in surgical specimens.</p><p><strong>Results: </strong>Cholesterol granulomas produce BTP and express high levels of BTP mRNA, but do not produce beta-2-transferrin.</p><p><strong>Conclusions: </strong>Beta-2 transferrin analysis is preferable to BTP analysis for the detection of CSF otorrhea because BTP may be false positive in the presence of cholesterol granulomas.</p>","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":" ","pages":"593-597"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Otology & NeurotologyPub Date : 2025-06-01Epub Date: 2025-02-24DOI: 10.1097/MAO.0000000000004481
Yousuf Khalil, John I Lane, Jeremy F Molligan, Jamie J Van Gompel, Kendall K Tasche, Matthew L Carlson
{"title":"A Rare Case of Osteoblastic Osteosarcoma of the Temporal Bone and Comprehensive Review of the Literature.","authors":"Yousuf Khalil, John I Lane, Jeremy F Molligan, Jamie J Van Gompel, Kendall K Tasche, Matthew L Carlson","doi":"10.1097/MAO.0000000000004481","DOIUrl":"10.1097/MAO.0000000000004481","url":null,"abstract":"<p><strong>Introduction: </strong>Although osteosarcoma represents the most common primary malignant bone tumor in children, they comprise only 0.2% of all cancers. Osteosarcoma frequently involves long bones; however, 8% of osteosarcomas involve the skull or mandible. Osteosarcoma is generally categorized based on location within the bone (central, surface, or extraskeletal) and histological grade (high-grade or low-grade). Osteoblastic osteosarcoma is a central, high-grade subtype and may be difficult to diagnose; it may present similarly to osteoblastoma, another rare, but benign, type of osteoblastic bone tumor. In this report, we present a rare case of osteoblastic osteosarcoma involving the temporal-occipital skull.</p><p><strong>Study design: </strong>Case report and systematic review.</p><p><strong>Setting: </strong>Tertiary referral center.</p><p><strong>Results: </strong>A 21-year-old male presented for assessment of a mass appearing over his left mastoid region, first noticed within the previous 12 months. He experienced growth of the lesion and pain that increased when pressure was applied to the mass. Results from fine needle aspiration and CT-guided core biopsy were positive for osteosarcoma, osteoblastic-type. Magnetic resonance imaging of the brain and skull base revealed the mass to be 2.8 cm in maximal diameter. Given a somewhat favorable location, the tumor could be completely excised en bloc with negative margins, and the patient subsequently received adjuvant chemotherapy. The patient is doing well at last follow-up 10 months after surgery, with no evidence of recurrence to date.</p><p><strong>Conclusion: </strong>The temporal bone is an uncommon location for a primary osteosarcoma, and there are numerous conditions that could present in a similar manner. This case highlights this rare occurrence of osteoblastic osteosarcoma of the temporal bone without previous exposure to radiation. There are a limited number of similar cases in the literature, and our report serves to bring awareness to this potential diagnosis and considerations related to treatment.</p>","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":" ","pages":"e198-e201"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Otology & NeurotologyPub Date : 2025-06-01Epub Date: 2025-02-20DOI: 10.1097/MAO.0000000000004460
Samuel P O'Rourke, Margaret E Richter, Lisa R Park, Emily Buss, Kevin D Brown, Margaret T Dillon
{"title":"Speech Recognition for Pediatric Electric-Acoustic Stimulation Users with Unilateral Hearing Loss.","authors":"Samuel P O'Rourke, Margaret E Richter, Lisa R Park, Emily Buss, Kevin D Brown, Margaret T Dillon","doi":"10.1097/MAO.0000000000004460","DOIUrl":"10.1097/MAO.0000000000004460","url":null,"abstract":"<p><strong>Objective: </strong>Pediatric cochlear implant (CI) recipients with unilateral hearing loss (UHL) and functional low-frequency acoustic hearing in the implanted ear could be fit with an electric-acoustic stimulation (EAS) device, which is the combination of acoustic and CI technologies in one device. Outcomes for this unique patient population are currently unknown. The present study assessed the speech recognition of pediatric EAS users with UHL.</p><p><strong>Study design: </strong>Retrospective review.</p><p><strong>Setting: </strong>Tertiary academic referral center.</p><p><strong>Patients: </strong>Pediatric CI recipients with functional acoustic hearing in the implanted ear (i.e., ≤ 80 dB HL) and a contralateral pure-tone average (0.5, 1, 2, and 4 kHz) ≤ 25 dB HL.</p><p><strong>Main outcome measures: </strong>Speech recognition was assessed with the consonant-nucleus-consonant (CNC) test for the affected ear preoperatively and at 6 and 12 months postactivation. Masked speech recognition was assessed with the Bamford-Kowal-Bench speech-in-noise test in the bilateral condition for three spatial configurations: target from the front and masker colocated with the target or presented 90° toward the implanted or contralateral ear.</p><p><strong>Results: </strong>Children experienced a significant improvement in CNC scores with EAS as compared to preoperative abilities with a hearing aid (F (2,7) = 10.0, p = 0.009). Preliminary masked sentence recognition data suggest a benefit in performance when the target was spatially separated from the masker, and a benefit with EAS as compared to an unaided listening condition.</p><p><strong>Conclusions: </strong>Children with UHL and functional acoustic hearing in the implanted ear experience better speech recognition with EAS as compared to preoperative abilities or listening unaided.</p>","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":" ","pages":"499-504"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Otology & NeurotologyPub Date : 2025-06-01Epub Date: 2025-03-20DOI: 10.1097/MAO.0000000000004497
Derya Ümit Talas, Orhan Beger, Onurhan Güven, Pourya Taghipour, Mesut Yeşilova, Deniz Uzmansel, Yusuf Vayısoğlu
{"title":"A Pilot Cadaveric Investigation Recommending the Lesser Petrosal Nerve as an Anatomical Landmark for Middle Fossa Approaches.","authors":"Derya Ümit Talas, Orhan Beger, Onurhan Güven, Pourya Taghipour, Mesut Yeşilova, Deniz Uzmansel, Yusuf Vayısoğlu","doi":"10.1097/MAO.0000000000004497","DOIUrl":"10.1097/MAO.0000000000004497","url":null,"abstract":"<p><strong>Objective: </strong>Ambiguity of certain reference points like the arcuate eminence and facial hiatus while approaching the middle fossa is not to be underestimated. This investigation proposes the use of the lesser petrosal nerve (LPN) as a novel landmark from which to determine the precise localization of the superior semicircular canal and internal acoustic canal.</p><p><strong>Subjects: </strong>Twelve adult cadavers (6 males and 6 females) aged 70.70 ± 15.10 years (range: 40-90 yr).</p><p><strong>Intervention: </strong>This clinical capsule covers the dissection report of 24 temporal bones.</p><p><strong>Main outcome measures: </strong>The numerical relationship of LPN to adjacent structures at the skull base was determined for middle fossa approaches.</p><p><strong>Results: </strong>The angles of LPN with the internal acoustic canal, greater superficial petrosal nerve, and superior semicircular canal were found to be 77.58 ± 12.78°, 7.43 ± 3.73°, and 112.01 ± 10.06°, respectively. The distance from the most posterior part of LPN to the head of the malleus was measured as 4.82 ± 1.58 mm.</p><p><strong>Conclusion: </strong>If the most posterior part of the groove for LPN is traced posteriorly for approximately 5 mm, the head of the malleus is reached by opening the tegmen tympani. Taking the medial margin of the head of the malleus as reference, a surgeon may find the superior semicircular canal, by following it along 110° posterior to the long axis of LPN. In addition, the surgeon may detect the internal acoustic canal, by tracing it along 78° posterior to the long axis of LPN. Our strategy is based on the initial identification of LPN and then access to SSC and IAC by forming a surgical map through LPN.</p>","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":" ","pages":"e202-e205"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143753949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Otology & NeurotologyPub Date : 2025-06-01Epub Date: 2025-03-26DOI: 10.1097/MAO.0000000000004479
Danielle R Larrow, Michael S Cohen
{"title":"Endoscopic Approach for Tympanostomy Tube Insertion in Patients With Trisomy 21.","authors":"Danielle R Larrow, Michael S Cohen","doi":"10.1097/MAO.0000000000004479","DOIUrl":"10.1097/MAO.0000000000004479","url":null,"abstract":"<p><strong>Abstract: </strong>Otitis media with effusion (OME) is common in children with Down syndrome (DS), affecting 93% of children by age 1 year and 68% of children by age 8 years ( 1,2 ). Resultant conductive hearing loss is present in up to 80% of children with DS and OME, making prompt treatment imperative to prevent adverse effects on language and development ( 2-4 ). Placement of tympanostomy tubes is common treatment for chronic OME with associated conductive hearing loss. However, tympanostomy tube insertion can be challenging in the DS population due to stenotic external auditory canals, a morphologically defining characteristic of DS seen in 40 to 50% of individuals ( 4 ). Adequate visualization is paramount not only for safe tympanostomy tube placement but also to allow for surveillance for retraction pockets, atelectasis, and cholesteatoma. Here, we demonstrate how the use of an endoscope can improve visualization and aid in difficult tube placement in this patient population.</p>","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":" ","pages":"e206"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143753977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Microscale Proteomic Analysis of the Endolymphatic Sac in Menière's Disease Patients.","authors":"Wenting Deng, Yuelian Luo, Haoyang Wu, Huilin Lao, Yafeng Zhu, Lingshuo Wang, Yuxuan Cao, Suijun Chen, Yongkang Ou, Hao Xiong","doi":"10.1097/MAO.0000000000004464","DOIUrl":"10.1097/MAO.0000000000004464","url":null,"abstract":"<p><strong>Objective: </strong>Endolymphatic hydrops is the primary pathological feature of Menière's disease (MD). An imbalance between endolymphatic fluid production and absorption due to endolymphatic sac (ES) dysfunction may be the major cause of endolymphatic hydrops. This study aimed to identify and characterize global protein expression of the ES in MD patients using microscale proteomics for the first time.</p><p><strong>Methods: </strong>Liquid chromatography-tandem mass spectrometry was used to analyze the ES samples from six MD patients and six acoustic neuroma (AN) patients (as control) for microscale proteomics and differentially expressed proteins (DEPs) were screened.</p><p><strong>Results: </strong>A total of 1,213 proteins in the ES were identified. Among them, there were 40 DEPs between the two groups. Of these proteins, 34 were upregulated (e.g., DPT and CHMP1B), and 6 were downregulated (e.g., PLPP3 and SCARB2) in the MD group compared to the AN group. DEPs were significantly enriched in coagulation and complement cascades.</p><p><strong>Conclusion: </strong>Microscale proteomics revealed a unique protein expression pattern in the ES of MD patients. Several proteins such as DPT, CHMP1B, and LTA4H may be involved in the pathogenesis of MD.</p>","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":" ","pages":"587-592"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Otology & NeurotologyPub Date : 2025-06-01Epub Date: 2025-04-11DOI: 10.1097/MAO.0000000000004491
Thomas James Hudson, Linette Shu Hwei Tan, Veronica Phillips, Jameel Muzaffar, Manohar Bance
{"title":"Long-Term Risk of Progression From Unilateral to Bilateral Méniere's Disease: A Systematic Review and Meta-Analysis.","authors":"Thomas James Hudson, Linette Shu Hwei Tan, Veronica Phillips, Jameel Muzaffar, Manohar Bance","doi":"10.1097/MAO.0000000000004491","DOIUrl":"https://doi.org/10.1097/MAO.0000000000004491","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the overall risk of conversion from unilateral to bilateral Méniere's disease (MD), the time interval from initial diagnosis to conversion, and any risk factors or audiometric trends associated with this process.</p><p><strong>Databases reviewed: </strong>Medline, Embase, Cochrane Library, Scopus, Web of Science, and ClinicalTrials.Gov.</p><p><strong>Methods: </strong>This review was reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Studies reporting longitudinal progression of unilateral to bilateral MD were included. Random-effects meta-analyses were performed to evaluate the proportion of cases that converted and the mean time to conversion, and a narrative synthesis described risk factors and audiometric data.</p><p><strong>Results: </strong>A total of 11 studies met the inclusion criteria. For overall conversion risk, meta-analysis of the 9 relevant studies (n = 1583) yielded a risk of 13% (95% CI, 12-15%). Mean time to conversion was 8.2 years (95% CI, 5.9-10.6; I2 = 46%), and a combined Kaplan-Meier analysis revealed a prolonged distribution of conversions including 10% that converted 20 years or later after initial diagnosis. Risk factors and audiometric data were sparsely reported, but there may be a correlation between conversion risk and first-sided ear surgery (protective), history of tympanic membrane perforation, and baseline hearing loss in the unaffected ear.</p><p><strong>Conclusion: </strong>There is a significant risk of conversion from unilateral to bilateral MD that must be taken into account when considering ablative treatment options, even late into its course. Further work will be required to better characterize risk/protective factors and audiometric trends.</p>","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":"46 5","pages":"485-493"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144034655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Idiopathic Sudden Sensorineural Hearing Loss Caused by Infarction of the Vestibulo-Cochlear Artery Can Be Detected by Testing Semicircular Canal Function and Audiometry: Proposal for Angiopathic Sudden Sensorineural Hearing Loss.","authors":"Nobuyoshi Tsuzuki, Kanako Masuda, Yoshiharu Yamanobe, Kohei Mizuno, Hiroyuki Ozawa, Koichiro Wasano","doi":"10.1097/MAO.0000000000004473","DOIUrl":"10.1097/MAO.0000000000004473","url":null,"abstract":"<p><strong>Background: </strong>Although the specific pathogenesis of idiopathic sudden sensorineural hearing loss (ISSNHL) remains unknown, vascular impairment is one of the leading causes of ISSNHL. Establishing diagnostic criteria for ISSNHL due to vascular impairment is essential. We hypothesized that isolated posterior semicircular canal dysfunction (IPSCD) in ISSNHL patients results from infarction of the vestibulo-cochlear artery (VCA). The aim of this preliminary retrospective study is to identify possible diagnostic characteristics of ISSNHL patients with IPSCD.</p><p><strong>Methods: </strong>Seventeen ISSNHL patients were enrolled. They underwent video head impulse testing within 28 days of ISSNHL onset between September 2019 and November 2023. We obtained patient characteristics and clinical information, including results of audiometric and balance function tests. Eligible patients were divided into two groups according to the presence or absence of IPSCD. Patient characteristics and clinical information of the two groups were compared.</p><p><strong>Results: </strong>Of the 17 ISSNHL patients included, 6 had IPSCD. Compared to the 11 patients without IPSCD, the 6 patients with IPSCD had significantly more coronary artery disease (odds ratio, infinite; p = 0.03) and had regularly used antithrombotic medications (odds ratio, infinite; p < 0.01). The audiogram shapes of the six ISSNHL-IPSCD patients were profound, flat, or high-frequency descending forms.</p><p><strong>Conclusions: </strong>Given that VCA impairment is associated with profound, flat, and high-frequency hearing loss and consistent with the arterial anatomy of the inner ear, ISSNHL-IPSCD patients are more likely to have vascular impairment. Conducting trials that target ISSNHL-IPSCD patients may lead to the discovery of new and effective treatments for ISSNHL.</p>","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":" ","pages":"616-620"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Otology & NeurotologyPub Date : 2025-06-01Epub Date: 2025-03-11DOI: 10.1097/MAO.0000000000004487
Heather J Smith, Samira Takkoush, Taylor J Mendenhall, Makenzie L Bramwell, Jason L Steele, Mana Espahbodi, Neil S Patel, Richard K Gurgel
{"title":"Hearing Benefits of Cochlear Implantation in Older Adults With Asymmetric Hearing Loss.","authors":"Heather J Smith, Samira Takkoush, Taylor J Mendenhall, Makenzie L Bramwell, Jason L Steele, Mana Espahbodi, Neil S Patel, Richard K Gurgel","doi":"10.1097/MAO.0000000000004487","DOIUrl":"10.1097/MAO.0000000000004487","url":null,"abstract":"<p><strong>Objective: </strong>To examine the benefit of cochlear implantation (CI) in older adults with single-sided deafness (SSD) and asymmetric hearing loss (AHL).</p><p><strong>Study design: </strong>Retrospective chart review.</p><p><strong>Setting: </strong>Veterans Affairs Medical Center and tertiary referral center, 2019-2023.</p><p><strong>Patients: </strong>Adults ≥60 years with either SSD or AHL who underwent unilateral CI.</p><p><strong>Interventions: </strong>Cochlear implantation.</p><p><strong>Main outcome measures: </strong>Audiometric testing (preoperative and postoperative pure-tone averages [PTA], sentence and word recognition), presence of hearing-related symptoms, CI utilization.</p><p><strong>Results: </strong>Twelve subjects were identified who underwent CI for SSD or AHL after being determined to obtain limited benefit from an appropriately fitted unilateral hearing aid (mean age 72.6 yr, 91.7% male, 100% White). Mean duration of hearing loss was 13.7 years, and the most common etiology was idiopathic (25%). Subjects were followed for a median length of 9.1 months after implantation. Mean daily CI use was 9.3 hours per day.Preoperatively, median unaided PTAs of the implanted and contralateral ear were 103.1 and 41.3 dB, respectively; median aided AZBio sentence recognition values in quiet were 0.0 and 81.5%, respectively. In the implanted ear with the CI in use, median PTA improved from 103.1 to 28.1 dB ( p = 0.002), CNC word scores improved from 0.0 to 42.0% ( p = 0.027), CNC phoneme scores improved from 0.0 to 60.0% ( p = 0.043), and AZBio improved from 0.0 to 48.0% ( p = 0.012). Seventy-five percent preoperatively, compared to 33.3% postoperatively, experienced dizziness ( p = 0.063), whereas 83.3 and 33.3% experienced tinnitus ( p = 0.375).</p><p><strong>Conclusions: </strong>In this group of older adults with SSD or AHL, CI demonstrated significant benefits in hearing thresholds and speech recognition in the implanted ear. Moreover, the average of 9.3 hours of daily use suggests that patients' CI is tolerated and beneficial in this population.</p>","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":" ","pages":"515-520"},"PeriodicalIF":1.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143616632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}