Otology & Neurotology最新文献

{"title":"Impact of Perioperative Anticoagulation and Antiplatelet Therapy on Hearing Preservation Outcomes.","authors":"Connie C Ma, Ankita Patro, Natalie R Schauwecker, Nathan R Lindquist, Michael H Freeman, Elizabeth L Perkins, David S Haynes, Kareem O Tawfik","doi":"10.1097/MAO.0000000000004394","DOIUrl":"https://doi.org/10.1097/MAO.0000000000004394","url":null,"abstract":"<p><strong>Objective: </strong>To report hearing preservation (HP) outcomes based on anticoagulation/antiplatelet use (blood thinner, BT) following cochlear implantation (CI).</p><p><strong>Study design: </strong>Retrospective cohort.</p><p><strong>Setting: </strong>Tertiary referral center.</p><p><strong>Patients: </strong>Three hundred twenty-six adults (361 ears: no BT = 210, BT held = 86, BT continued = 65) implanted between 2012 and 2021 with preoperative low-frequency pure-tone average (LFPTA) of 65 dB HL or better.</p><p><strong>Main outcome measure: </strong>Postoperative HP, defined as LFPTA ≤80 dB HL, at 1, 3, 6, and 12 months.</p><p><strong>Results: </strong>Compared to no BT, the BT held and continued groups were older (60.6 vs 72.7 vs 73.0 yrs, p < 0.001) and had diabetes (10% vs 28% vs 22%, p < 0.001). Electrode type, steroid use, surgical approach, and preoperative LFPTA were equivalent among groups. Postoperative HP rates were significantly higher for no BT than the BT held and continued groups at 1 month (62% vs 48% vs 43%, p = 0.008), with equivalent results at 3, 6, and 12 months. When patients were stratified by BT type, there were no significant differences in HP outcomes. On multivariate analysis, BT status was not a significant predictor of HP rates at 1 or 12 months. Younger age (OR 0.95, 95% CI 0.94-0.97, p < 0.001) was the only significant predictor of 1- but not 12-month HP.</p><p><strong>Conclusions: </strong>BT use, regardless of whether held for surgery, was associated with inferior early HP outcomes. After controlling for age, BT status was not a significant predictor of HP, suggesting inherently poorer cochlear health in patients who are on BTs.</p>","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Relationship between Chronic Unilateral Hearing Loss, Balance Function, and Falls Is Not Informed by Vestibular Status.","authors":"Anat V Lubetzky, Jennifer L Kelly, Katherine Scigliano, Brittani Morris, Kristyn Cheng, Daphna Harel, Maura Cosetti","doi":"10.1097/MAO.0000000000004400","DOIUrl":"https://doi.org/10.1097/MAO.0000000000004400","url":null,"abstract":"<p><strong>Objectives: </strong>Recent studies suggest that hearing loss is associated with balance dysfunction and an increased risk of falls. The purpose of this study was to investigate whether adults with unilateral hearing loss (UHL) have an underlying vestibular dysfunction and whether vestibular testing explains balance function and fall risk.</p><p><strong>Study design: </strong>Cross-sectional.</p><p><strong>Setting: </strong>Urban otology practice and a human motion laboratory.</p><p><strong>Patients: </strong>We recruited 41 healthy controls (mean age, 52 years; range, 22-78 years) and 29 adults with stable UHL (mean age, 53 years; range, 18-80 years) who denied symptoms of dizziness (Dizziness Handicap Inventory average, 1.86; range, 0-14). UHL occurred an average of 4 years (range from sudden loss, 4 months to 27.5 years) prior to testing.</p><p><strong>Interventions: </strong>We conducted the caloric portion of the videonystagmography test, video head impulse test (vHIT), and a battery of balance tests: standing on foam with eyes closed, timed up and go test, four square step test, 10-meter walk, and a virtual reality (VR) assessment of postural control.</p><p><strong>Main outcome measures: </strong>Hearing was quantified by four-frequency pure-tone average (PTA). Caloric weakness was defined as asymmetry greater than 25%. Participants self-reported falls over the past 12 months and history of vertigo. Performance on balance tests was quantified by time to completion or duration of hold. Performance on the VR assessment was quantified by root-mean-square velocity of head sway.</p><p><strong>Results: </strong>Proportion of unilateral caloric weakness was significantly higher in the UHL group (25%) than the control group (12%). Five participants with UHL refused caloric testing. vHIT gains of lateral canals were normal in both groups. The majority of participants in the UHL group experienced vertigo at the onset of hearing loss (72%). There were five fallers in the UHL group (17%) and three in the control group (7%). Participants with caloric weakness or vertigo at onset did not differ from those without in age or in any of the balance tests. Participants with history of falls differed in head sway and duration of hold standing on foam with eyes closed.</p><p><strong>Conclusions: </strong>Individuals with UHL are more likely to have caloric weakness than healthy controls; however, these findings are not correlated with functional outcomes or history of falls. Postural control testing using virtual reality or standing on foam with eyes closed may help detect those at a risk for falls.</p>","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating the Necessity of Ear Packing After Otologic Surgery: A Randomized Controlled Trial.","authors":"Alper Tabaru, Zeliha Kapusuz Gencer, Sahin Ogreden, Salih Akyel, Iskender Bayram","doi":"10.1097/MAO.0000000000004399","DOIUrl":"https://doi.org/10.1097/MAO.0000000000004399","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to evaluate the necessity of ear packing in otological operations where the annulus fibrosus is not elevated, focusing on graft success rates and postoperative hearing outcomes.</p><p><strong>Methods: </strong>A randomized controlled prospective clinical trial was conducted at a tertiary care hospital involving 200 patients aged 18 years and above undergoing myringoplasty for inactive chronic suppurative otitis media. Patients were randomly assigned to receive either ear packing with absorbable gelatin sponge (Gelfoam®) or no packing. The primary outcome is graft success assessed via microscopic examination at 3 and 6 months post-surgery. Secondary outcomes include hearing gains measured by pure-tone audiometry at 500-, 1000-, 2000-, and 4000-Hz frequencies.</p><p><strong>Results: </strong>At 3 months, the graft take rate was 92% in the ear packing group and 90% in the no packing group, with no statistically significant difference (p = 0.63). At 6 months, the graft take rate was 90% in the packing group and 88% in the no packing group (p = 0.67). Hearing improvements, as measured by air conduction thresholds, were also similar between the two groups (p = 0.73).</p><p><strong>Conclusion: </strong>This study demonstrates that myringoplasty without ear packing yields comparable graft take rates and hearing improvements to traditional myringoplasty with ear packing. These findings suggest that omitting ear packing in appropriate cases may simplify the procedure without compromising patient outcomes.</p>","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of Prolonged Hospital Stay After Microsurgery for Vestibular Schwannoma: Analysis of a Decade of Data.","authors":"Mohamed A Aboueisha, Regan Manayan, Kevin Tie, Peter P Issa, Mohamed A Al-Hamtary, Victoria Huang, James G Naples","doi":"10.1097/MAO.0000000000004320","DOIUrl":"10.1097/MAO.0000000000004320","url":null,"abstract":"<p><strong>Importance: </strong>Microsurgical resection is one of the treatments for vestibular schwannomas (VS). While several factors have been linked to increased length of stay (LOS) for VS patients undergoing microsurgery, a better understanding of these factors is important to provide prognostic information for patients.</p><p><strong>Objective: </strong>Determine predictors of increased LOS for VS patients undergoing microsurgical resection.</p><p><strong>Design: </strong>Retrospective analysis using the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database from 2010 to 2020.</p><p><strong>Setting: </strong>Database review.</p><p><strong>Participants: </strong>All patients who underwent microsurgery (CPT codes 61520, 61526/61596) for the management of vestibular schwannoma (ICD9 and ICD10 codes 225.1, D33.3) were included.</p><p><strong>Main outcomes and measures: </strong>Analyzing perioperative factors that can predict prolonged hospital stay.</p><p><strong>Results: </strong>A total of 2096 cases were identified and 1,188 (57%) of these patients were female. The mean age was 51.0 ± 14.0 years. Factors contributing to prolonged LOS included African American race (OR = 2.11, 95% CI: 1.32-3.36, p = 0.002), insulin-dependent diabetes mellitus (OR = 2.12, 95% CI: 1.09-4.4.11, p = 0.026), hypertension (OR = 1.26, 95% CI: 1-1.58, p = 0.046), functional dependency (OR = 5.22, 95% CI: 2.31-11.79, p = 0.001), prior steroid use (OR = 1.96, 95% CI: 1.18-3.15, p = 0.009), ASA class III (OR = 2.06, 95% CI: 1.18-3.6, p < 0.011), ASA class IV (OR = 6.34, 95% CI: 2.62-15.33, p < 0.001), and prolonged operative time (OR = 2.14, 95% CI: 1.76-2.61). Microsurgery by a translabyrinthine (TL) approach compared to a retrosigmoid (RSG) approach had lower odds of prolonged LOS (OR = 0.67, 95% CI: 0.54-0.82, p < 0.001). In a separate analysis regarding patients receiving reoperation, operative time was the only predictor of prolonged LOS (OR = 2.77, 95% CI: 1.39-5.53, p = 0.004.).</p><p><strong>Conclusions and relevance: </strong>Our analysis offers an analysis of the factors associated with a prolonged LOS for the surgical management of VS. By identifying healthcare disparities, targeting modifiable factors, and applying risk stratification based on demographics and comorbidities, we can work toward reducing disparities in LOS and enhancing patient outcomes.</p>","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":" ","pages":"1159-1166"},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142292887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Congenital Cytomegalovirus Infection and Hearing Loss: It's Time to Screen.","authors":"Javier K Nishikawa, Pablo J Sánchez","doi":"10.1097/MAO.0000000000004323","DOIUrl":"10.1097/MAO.0000000000004323","url":null,"abstract":"<p><p>Congenital CMV infection is the leading nongenetic cause of sensorineural hearing loss worldwide, yet most parents have never heard of it. The majority of infected newborns have no clinical signs of infection, although a substantial proportion may have hearing loss at birth or develop it later in life. As antiviral treatment with ganciclovir or valganciclovir initiated in the first month of age improves audiologic outcomes, there is an urgent need for timely identification of infected neonates. A targeted approach that tests neonates who refer on the newborn hearing screen has been implemented in many states and hospital programs, but it fails to identify about 40% of children who experience CMV-related hearing loss. A universal screening approach is optimal given the prevalence of congenital CMV infection, its associated sequelae, the availability of a simple saliva screening tool, the available antiviral treatment, and the directed therapies for hearing impairment.</p>","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":"45 10","pages":"e702-e709"},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142605627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How to Teach an \"Old Dog\" New Tricks: Improving Clinical Efficiency in a Well-Established Cochlear Implant Program.","authors":"Meredith A Holcomb, Molly R Smeal","doi":"10.1097/MAO.0000000000004300","DOIUrl":"10.1097/MAO.0000000000004300","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the implementation of a new streamlined service delivery model for cochlear implant (CI) patients at a mature academic CI program.</p><p><strong>Setting: </strong>Tertiary referral center.</p><p><strong>Patients: </strong>CI candidates and CI users.</p><p><strong>Interventions: </strong>Implementation of a new CI service delivery model.</p><p><strong>Main outcome measures: </strong>CI surgical numbers, conversion rate from CI evaluation to surgery, documentation time, number of visits for new versus established CI users, ratio of CI clinical full-time equivalency to CI surgical numbers, time from CI referral to CI evaluation, patient travel burden.</p><p><strong>Results: </strong>De-identified data from the electronic health record (EHR) were used to develop an efficiency improvement plan. With the old clinical model, audiologists' schedules were at capacity, wait for CI evaluation appointments was prolonged, and CI surgical numbers were declining. The new model implemented an interactive electronic medical record, a de-escalated postoperative programming schedule, inclusion of telehealth pre-CI surgery, and an evidence-based approach to CI programming. After a 4-year time period (2019-2022) of implementing clinical improvement strategies, the postoperative CI programming schedule in the first year after activation was reduced from 10 visits (unilateral CI user) and 16 visits (bilateral CI user) to 4 visits total. This saved the patient up to 16 hours of time at the clinic, reduced travel burden, and opened 19 weeks of appointment slots for new patients. Increased utilization of the EHR and telehealth increased the conversion rate from CI evaluation to CI surgery by 33% and decreased the no-show rate by 5%. Annual CI surgical numbers subsequently increased by 45% with the new model, which increased our program's CI utilization rate and reduced our role as a barrier to CI care.</p><p><strong>Conclusion: </strong>If CI programs wish to be instrumental in improving CI utilization rates, clinical care models need to be adapted now in preparation for the projected rise in the number of potential CI candidates. This streamlined clinical efficiency model serves as an example of patient-centered CI care that can be recreated at other institutions. Outcomes from our 4-year strategic initiative will add to the scarcity of literature in this area.</p>","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":"45 10","pages":"e735-e742"},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142605739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Proceedings From the Dallas 2023 Cochlear Implants (CI) in Children and Adults Symposium.","authors":"Donna Sorkin, Kara Leyzac, Aaron C Moberly","doi":"10.1097/MAO.0000000000004360","DOIUrl":"10.1097/MAO.0000000000004360","url":null,"abstract":"","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":"45 10","pages":"e700-e701"},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142605763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Relationship Between eSRTs and Upper Stimulation Levels in a Large Cohort of Adult Cochlear Implant Recipients.","authors":"Jourdan T Holder, Jennifer Hoffman, Haley Williams, René H Gifford","doi":"10.1097/MAO.0000000000004329","DOIUrl":"10.1097/MAO.0000000000004329","url":null,"abstract":"<p><strong>Objective: </strong>To compare electrically evoked stapedial reflex thresholds (eSRTs) measured at 1 month post-activation to upper stimulation levels used for programming adult cochlear implant (CI) recipients over time in a large clinical population.</p><p><strong>Study design: </strong>Review of prospectively collected clinical database.</p><p><strong>Setting: </strong>Large CI program at an academic medical center.</p><p><strong>Patients: </strong>Postlingually deafened adult CI recipients (n = 439).</p><p><strong>Main outcome measures: </strong>eSRTs recorded in the medical record and upper stimulation levels derived from the programming software at 1 and 6 months post-activation.</p><p><strong>Results: </strong>The correlation between eSRTs and upper stimulation levels was strong for all three manufacturers (r = 0.80-0.86). On average, upper stimulation levels were set 15.4 clinical levels below eSRT for Cochlear using a pulse width of 25 microseconds, 13.4 clinical levels below eSRT for Cochlear using a pulse width of 37 microseconds, 11.3 clinical units below eSRT for Advanced Bionics, and 0.1 charge unit above eSRT for MED-EL. eSRTs were found to be elicited at similar levels for different electrodes/frequencies across the array. After upper stimulation levels were set based on eSRT at 1 month post-activation, there was no significant change in upper stimulation levels between 1 and 6 months post-activation.</p><p><strong>Conclusions: </strong>eSRTs and upper stimulation levels are highly correlated. Average differences between eSRTs and upper stimulation levels reported herein can be used to guide programming in the clinic. Further, when eSRTs are used to program upper stimulation levels, upper stimulation levels should be relatively similar across channels and stable over time.</p>","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":"45 10","pages":"e756-e762"},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11566993/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142605785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cochlear Implantation for Single-Sided Deafness in Pediatric Patients: A Critical Assessment of Usage Rate.","authors":"Robert J Macielak, Celine Richard, Prashant S Malhotra, Oliver F Adunka, Ursula M Findlen","doi":"10.1097/MAO.0000000000004331","DOIUrl":"10.1097/MAO.0000000000004331","url":null,"abstract":"<p><strong>Objective: </strong>To assess the usage rate of pediatric patients undergoing cochlear implantation (CI) for single-sided deafness (SSD).</p><p><strong>Study design: </strong>Retrospective cohort study.</p><p><strong>Setting: </strong>Tertiary care pediatric referral center.</p><p><strong>Patients: </strong>Pediatric patients who underwent CI for SSD.</p><p><strong>Interventions: </strong>CI with requisite audiometric follow-up.</p><p><strong>Main outcome measures: </strong>Device use and audiometric testing.</p><p><strong>Results: </strong>Sixty-six patients were implanted for SSD between 8/2015 and 7/2023 at a median age of 4.7 years (interquartile range, 1.7-7.7 yr). The cause of hearing loss was unknown in the majority of cases (28 patients, 42%), with cytomegalovirus being the most common known cause (17 patients, 26%). Hearing loss was prelingual in 38 patients (58%). Post-implantation, 12 patients (18%) were identified as lost to follow-up. For the remaining 54 patients, the median length of audiometric follow-up was 1.4 years (interquartile range, 0.9-2.2 yr). At last evaluation, only 10 of these 54 patients (19%) were designated as users (≥6 h per day), and 13 patients (24%) were designated as limited users (>2 but <6 h per day). Of patients capable of performing speech-in-noise testing (n = 13), 11 patients (85%) showed improvement on BKB-SIN SNR-50 testing with their implant on versus off with a mean improvement of 3 dB. Notably, 4 of these 11 patients (36%) were categorized as nonusers despite this benefit.</p><p><strong>Conclusions: </strong>Despite audiometric benefit from CI in the pediatric SSD population, usage rates over time remain markedly lower than anticipated at a high-volume, well-resourced tertiary care pediatric center. No influencing factors were identified, warranting critical assessment to ensure appropriate resource allocation.</p>","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":" ","pages":"1122-1127"},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142392305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vestibular Dysfunction in Patients With Sickle Cell Disease: A Systematic Review.","authors":"Jonathan Laredo, Sofia Torres-Small, Lin Wu, Tomoko Makishima, Celine Richard","doi":"10.1097/MAO.0000000000004327","DOIUrl":"10.1097/MAO.0000000000004327","url":null,"abstract":"<p><strong>Introduction: </strong>Sickle cell disease (SCD) often leads to sensorineural hearing loss due to vaso-occlusive events in the cochlear vasculature. Although the vestibule and cochlea share a blood supply, information on vestibulopathy in SCD is limited. This systematic review aims to consolidate current knowledge on vestibular dysfunction in SCD patients.</p><p><strong>Methods: </strong>This study, registered on PROSPERO, involved a thorough electronic search using MEDLINE-Ovid, Embase, Google Scholar, The Cochrane Library, and Scopus databases from inception to December 2023. Data extraction adhered to PRISMA guidelines. Authors independently assessed bias and evidence quality using NIH Study Quality Assessment tools. Inclusion criteria covered articles mentioning vestibular symptoms in SCD patients, whereas exclusion criteria comprised non-English articles and vestibular symptoms limited to treatment side effects.</p><p><strong>Results: </strong>Out of 2,495 studies, only 12 met the criteria. Among SCD patients undergoing head imaging, 19% reported inner ear complaints, and 70% experienced dizziness/imbalance. In a group of SCD children, there was a significant relationship between endothelial dysfunction and vertigo duration. The recommended imaging sequence was T1-weighted thin-section temporal bone MRIs, which revealed abnormal findings even without clinical symptoms. Imaging showed labyrinthine hemorrhage and labyrinthitis ossificans, mostly unilateral. Vestibular symptoms emerged with older age, suggesting cortical compensation kept most subjects asymptomatic. In asymptomatic adult SCD patients, there was no significant difference compared with controls in tracking test batteries and positional tests; however, saccadic latency was longer in SCD patients.</p><p><strong>Conclusion: </strong>The existing data on vestibulopathy in SCD were limited and often of poor quality. Although a connection between SCD and vestibular symptoms was noted, information on treatment approaches was scant. Further research in this area could contribute to the early diagnosis of vestibular dysfunction, potentially enhancing outcomes for SCD patients.</p>","PeriodicalId":19732,"journal":{"name":"Otology & Neurotology","volume":" ","pages":"1098-1107"},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142392307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}