One Health最新文献

{"title":"Detection and characterization of Langya virus in Crocidura lasiura (the Ussuri white-toothed shrew), Republic of Korea","authors":"Augustine Natasha ,&nbsp;Sarah E. Pye ,&nbsp;Kyungmin Park ,&nbsp;Shivani Rajoriya ,&nbsp;Intae Yang ,&nbsp;Jieun Park ,&nbsp;Haryo Seno Pangestu ,&nbsp;Jongwoo Kim ,&nbsp;Yeonsu Oh ,&nbsp;Carolina B. López ,&nbsp;Jin-Won Song ,&nbsp;Won-Keun Kim","doi":"10.1016/j.onehlt.2025.101017","DOIUrl":"10.1016/j.onehlt.2025.101017","url":null,"abstract":"<div><div>Langya virus (LayV) is the only documented zoonotic agent within the shrew borne <em>Parahenipavirus</em> genus. Other <em>Parahenipavirus</em> species, including Gamak virus and Daeryeong virus, have been discovered in the Republic of Korea, highlighting the prevalence of this genus in the region. We retrospectively analyzed metagenomic next-generation sequencing of two <em>Crocidura lasiura</em> (the Ussuri white-toothed shrew) kidney samples from 2017, followed by paramyxovirus screening of 24 kidney samples from the same species collected in 2023. The LayV positivity rate was 12.5 % (3 of 24). Amplicon-based sequencing was subsequently developed to obtain the complete viral sequences. Five complete genomes of Langya virus Korea (LayV KOR) were identified: two from 2017 samples and three from 2023 samples. LayV KOR exhibited approximately 80 % and 95.5 % homology at the nucleotide and amino acid levels, respectively. Phylogenetic analysis underscored the close relationship between LayV KOR and LayV from China. This study represents the first detection of LayV complete sequences in shrews outside of China.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"20 ","pages":"Article 101017"},"PeriodicalIF":4.1,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143685946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DNA metabarcoding analysis revealed a silent prevalence of environmental pathogenic Leptospira in urban area of Okinawa Island, Japan","authors":"Yukuto Sato ,&nbsp;Yuiko Hiyajo ,&nbsp;Taisei Tengan ,&nbsp;Tsurua Yoshida ,&nbsp;Yoichiro Uchima ,&nbsp;Michinari Tokeshi ,&nbsp;Kaori Tsurui-Sato ,&nbsp;Claudia Toma","doi":"10.1016/j.onehlt.2025.101016","DOIUrl":"10.1016/j.onehlt.2025.101016","url":null,"abstract":"<div><h3>Objective</h3><div>Human activities, such as agriculture, environmental manipulation, and city development, have impacted the distribution of flora, fauna, and microbes (including potential human pathogens) at the global level. This study focused on the bacterial genus <em>Leptospira</em>, an organism causing leptospirosis that is prevalent in tropical and subtropical regions. We hypothesized that although only a few cases of leptospirosis have been reported in the urban region of main island of Okinawa Prefecture (Okinawa Island, OKI), Japan, <em>Leptospira</em> is present in these regions.</div></div><div><h3>Methods</h3><div>Thirty-four samples were collected from rivers in urban OKI and rural Ishigaki Island (ISG) and analyzed to determine the distribution of <em>Leptospira</em> and mammals using environmental DNA (eDNA) metabarcoding. High-throughput sequencing analysis was performed to sequence the polymerase chain reaction products of partial leptospiral 16S rRNA and vertebrate mitochondrial 12S rRNA genes from 16 and 18 river samples of OKI and ISG, respectively, including the waters collected from <em>Leptospira</em>-endemic areas in ISG.</div></div><div><h3>Results</h3><div><em>Leptospira noguchii</em> and <em>L. interrogans</em>-related, two <em>Leptospira</em> species of the P1+ clade that are pathogenic to humans and mammals, were repeatedly detected in OKI and ISG, supporting our hypothesis. The sequence numbers of the five <em>Leptospira</em> species of P1– and P2 clades showed significant correlations with those of cattle (<em>Bos taurus</em>) in OKI; however, the potential host animals for P1+ species remain unclear. The total number of leptospiral sequences obtained from the ISG samples was correlated with the distance from the mountainous woodlands.</div></div><div><h3>Conclusion</h3><div>The pathogenic P1+ <em>Leptospira</em> was distributed in urban OKI, in addition to rural ISG. The factors correlated with leptospiral detection, that is, cattle eDNAs and the distance from mountainous forests in OKI and ISG, respectively, suggest the silent prevalence of <em>Leptospira</em> in urban and developing regions related to human activities. The findings of the present study provide insights into public health in cities with respect to climate change and possible flood damage.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"20 ","pages":"Article 101016"},"PeriodicalIF":4.1,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143705125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular evidence of host range expansion of Enterocytozoon bieneusi in captive wildlife at Beijing Zoo, China","authors":"Zhiyang Pei ,&nbsp;Bowen Zhang ,&nbsp;Yongqiang He ,&nbsp;Qianming Zhao ,&nbsp;Fuchang Yu ,&nbsp;Ting Jia ,&nbsp;Zhenjie Zhang ,&nbsp;Meng Qi","doi":"10.1016/j.onehlt.2025.101011","DOIUrl":"10.1016/j.onehlt.2025.101011","url":null,"abstract":"<div><div><em>Enterocytozoon bieneusi</em> has become a significant public health concern due to its ability to infect both humans and animals on a global scale. However, there is a paucity of epidemiological data regarding this pathogen in captive wildlife. In this study, 445 fecal samples were collected from captive animals at Beijing Zoo and analyzed using PCR targeting the internal transcribed spacer (ITS) of the nuclear ribosomal DNA of <em>E. bieneusi</em>. The overall prevalence was determined to be 7.0 % (31/445), with infection rates of 7.1 % (23/322) in mammals and 6.5 % (8/123) in Aves. Genotypic characterization 12 distinct genotypes, including 11 known genotypes belonging to Groups 1 (EbpA, PigEBITS7, D, HND-1, SC02, CM16, MJ13), 2 (BEB6), 7 (CM 4), and 13 (CHB1, CHK1), along with one novel genotype (BJZ-1) in Group 1. The detection of zoonotic genotypes from Groups 1 and 2 underscores the potential for cross-species transmission between captive wildlife and humans. Notably, this study presents the first molecular identification of <em>E. bieneusi</em> in caracals, polar bears, giant anteaters, and grey herons, thereby significantly expanding the known host range of this pathogen. These findings emphasise the necessity of implementing One Health surveillance strategies to monitor and mitigate zoonotic risks at the human-animal interface.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"20 ","pages":"Article 101011"},"PeriodicalIF":4.1,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143654540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regulations, biosecurity measures, and impact of COVID-19: A comprehensive mixed method study in traditional wet and live animal markets in Bangladesh","authors":"Sukanta Chowdhury ,&nbsp;Tushar Kumar Das ,&nbsp;Nurun Nahar Chisty ,&nbsp;Sajal Kanti Biswas ,&nbsp;Mohammed Ziaur Rahman ,&nbsp;Jiaxin Ling ,&nbsp;Mahmoud M. Naguib ,&nbsp;Johanna F. Lindahl","doi":"10.1016/j.onehlt.2025.101014","DOIUrl":"10.1016/j.onehlt.2025.101014","url":null,"abstract":"<div><h3>Background</h3><div>Traditional wet and live animal markets (TWLAMs) offer fresh vegetables, meat, fish, and live animals to consumers at affordable prices. The daily operation of TWLAMs is crucial for supplying safe food by controlling and preventing contamination from food-borne pathogens.</div></div><div><h3>Objectives</h3><div>A cross-sectional study was conducted in 10 TWLAMs to collect and assess data on market regulations, biosecurity measures, and the impact of COVID-19 on food supply and livelihoods.</div></div><div><h3>Methods</h3><div>We interviewed 40 key informants and performed on-site observations. Additionally, we organized a workshop with different stakeholders including experts in human health, animal health, food safety, zoonotic diseases, agriculture, consumer rights, and market regulations.</div></div><div><h3>Results</h3><div>Among the 10 surveyed TWLAMs, five (50 %) were governed by the City Corporation, six (60 %) had written operational guidelines, while 40 % were unaware of any government regulations. Most markets (80 %, <em>n</em> = 8) lacked direct water supply lines for their shops, and 50 % had no functional drainage systems. A majority (55 %, <em>n</em> = 22) of the key informants reported not seeing any food inspectors at the market within the last three months. Only 60 % (<em>n</em> = 24) believed that live animals could transmit diseases to humans within wet markets. While shop-level cleaning was regularly conducted, cleaning of the entire market was infrequent. COVID-19 had both negative and positive impacts on TWLAM. The most common negative effects were job losses (65 %) and increased living expenses (67 %), while COVID-19 led to improvements in market hygiene (100 %), personal hygiene (100 %), and adherence to social distancing (100 %). No permanent closures or bans on animal trading were reported in TWLAM during the COVID-19 pandemic. All workshop participants (<em>n</em> = 55) indicated that shifting from live animal trading to processed animal products would be challenging due to cultural norms and practices.</div></div><div><h3>Conclusions</h3><div>Despite many challenges and shortcomings, a unique operational guideline could help ensure the supply of safe food to consumers. Financial incentives, certification, training, and regular monitoring can improve practices associated with food safety.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"20 ","pages":"Article 101014"},"PeriodicalIF":4.1,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143685945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing coupling coordination between human-animal-environmental health for advancing uniform progress in One Health","authors":"Ya Tian ,&nbsp;Zonghan Li ,&nbsp;Xueyi Luo ,&nbsp;Zheng Hu ,&nbsp;Tong Xu ,&nbsp;Kai Wu ,&nbsp;Min Cao ,&nbsp;Prajal Pradhan ,&nbsp;Min Chen ,&nbsp;Hui Lin","doi":"10.1016/j.onehlt.2025.101013","DOIUrl":"10.1016/j.onehlt.2025.101013","url":null,"abstract":"<div><div>The One Health (OH) approach aims to sustainably balance and optimise the health of people, animals, and ecosystems. However, there is a lack of robustly quantified insights into its spatiotemporal coupling and coordination. This study employs the OH index, which incorporates Sustainable Development Goals (SDGs), to examine the coupling and coordination relationships among three health subsystems, elucidate their four spatiotemporal patterns, and identify key driving factors. Our results indicate that the degree of OH coupling coordination is improving, despite spatial unevenness across SDG regions. Countries with varying economic levels often exhibit similar coupling coordination patterns, suggesting the potential for policy coherence to foster regionally uniform development. Key factors for breaking the cycle of poverty include increased health spending, improved education, and better dietary balance. In regions facing significant economic and environmental pressures, promoting animal and environmental health through biodiversity conservation and habitat preservation is essential for achieving OH coupling coordination. Nevertheless, the absence of governance mechanisms, along with factors such as climate change, military conflicts, and fragile alliances, poses serious obstacles to achieving uniform OH. Therefore, this study underscores the necessity of targeted policy interventions, interdisciplinary collaboration, and comprehensive governance to address this unevenness, promote coordination, and advance global health governance.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"20 ","pages":"Article 101013"},"PeriodicalIF":4.1,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143654539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sixth wave of global public health progress","authors":"Jesus Cortes ,&nbsp;Deborah Aluh ,&nbsp;Inês Fronteira ,&nbsp;Diana Gil ,&nbsp;Pedro Aguiar","doi":"10.1016/j.onehlt.2025.101015","DOIUrl":"10.1016/j.onehlt.2025.101015","url":null,"abstract":"<div><div>The “Sixth Wave of Global Public Health Progress” concept introduces a transformative approach to address contemporary health challenges by leveraging historical advancements and innovative strategies. This wave emphasizes the integration of data-driven decision-making, personalized public health, and technological innovations, such as artificial intelligence and digital tools, to enhance global health outcomes. By focusing on the connectedness of human, animal, and environmental health systems through the One Health approach, the framework aims to tackle critical threats like climate change, pandemics, and social inequities. It advocates for global collaboration, community-centric approaches, and sustainable practices to ensure equitable health access. Ultimately, this paper proposes a comprehensive framework that catalyzes social and scientific discourse, paving the way for resilient and adaptive health systems that align with the United Nations' Sustainable Development Goals.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"20 ","pages":"Article 101015"},"PeriodicalIF":4.1,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143714786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Behavioral risk assessment of exposure to wild and domestic animals in response to a Marburg virus disease outbreak, Ghana 2022","authors":"Richard Suu-Ire ,&nbsp;Shannon Ball ,&nbsp;Meyir Yiryele Ziekah ,&nbsp;Jean DeMarco ,&nbsp;Morgan Kain ,&nbsp;Amos Sarpong Agyei ,&nbsp;Jonathan H. Epstein","doi":"10.1016/j.onehlt.2025.101010","DOIUrl":"10.1016/j.onehlt.2025.101010","url":null,"abstract":"<div><div>In July 2022, Ghana reported its first outbreak of Marburg virus disease (MVD). The source of the outbreak was unknown. In August 2022 we conducted a behavioral risk assessment, surveying 715 participants in three rural communities associated with the presumptive index case: Site 1 in Ashanti Region and Sites 2 and 3 in the Western Region of Ghana. Our primary aim was to characterize exposure to wild and domestic animals, specifically Egyptian rousette bats (ERBs), the natural reservoir for Marburg virus. We focused on two primary routes of potential exposure to ERBs: 1) eating fruit bearing bite marks and 2) entering caves or mines where bats were present. Eating fruit bearing bite marks was common across all sites, but highest at Site 2 in the Western Region. Higher levels of education were negatively correlated with eating fruit bearing bite marks, while having fruit trees present on the participant's home compound increased the odds of this exposure. Residents in Site 3 were significantly more likely to be exposed to bats in caves and mines. Participants across all sites also reported high levels of exposure to bats inside buildings; while ERBs do not typically roost in buildings, this presents a potential risk of exposure to other bat-associated pathogens. One participant at Site 3 reported symptoms consistent with MVD in the previous four months, suggesting the possibility of unrecognized cases that may have been associated with the outbreak. This study identified behaviors within the outbreak regions that could increase the risk of exposure to Marburg virus and other bat-borne pathogens. Serological surveys in these communities would provide important information about the extent of the Marburg outbreak by identifying unreported cases, as well as exposure to other filoviruses.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"20 ","pages":"Article 101010"},"PeriodicalIF":4.1,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143705124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Promoting risk communication and community engagement during Mpox outbreak in fragile conflict zones of Eastern DRC","authors":"Simon Binezero Mambo ,&nbsp;Glory Mbe Egom Nja ,&nbsp;Umi Omar Bunu ,&nbsp;Gloria Neema Bizimana ,&nbsp;Amos M'yisa Makelele ,&nbsp;Fatuma Djuma Sonia ,&nbsp;Malcolm K. Jones ,&nbsp;Franck Katembo Sikakulya","doi":"10.1016/j.onehlt.2025.101012","DOIUrl":"10.1016/j.onehlt.2025.101012","url":null,"abstract":"<div><div>The Democratic Republic of the Congo (DRC) declared a national outbreak of monkeypox (Mpox) in December 2022, and in February 2023, an incident management system was implemented. As of May 26, 2024, the DRC had recorded 7851 cases of Mpox, with 384 fatalities. The number of confirmed cases in the province has been increasing. Of all cases, 117 (36 %) were individuals living in camps for Internally Displaced People (IDP) in North and South Kivu provinces. These provinces are currently considered as foci of the outbreak.</div><div>The challenges of this outbreak in Eastern DRC, where there exist high levels of general insecurity, distrust of government and foreign actors, and ongoing violence, have contributed to widespread community resistance to potentially lifesaving interventions. The complex relationship between armed conflict and public health highlights the need for a One Health approach to address both short-term and long-term health challenges in conflict-affected regions. Armed conflict often disrupts healthcare systems, making it difficult for people to access diagnosis, treatment, and prevention services, thus leading to increased disease transmission and severe outcomes. An effective Risk Communication and Community Engagement (RCCE) strategy is the bedrock to addressing these specific needs of people in conflict zones and improving their acceptability of health interventions. A One Health approach integrating RCCE would empower communities to manage risks, identify outbreaks and avoid infected animals, improving community acceptability to public health interventions. In the delicate war zones of the DRC, conveying emergency concerns related to Mpox is a worry in terms of preserving and fostering trust in the government. This paper seeks to highlight the need for urgent intervention by the local and global public health communities to work together to put stronger policies and long-term plans into place that prioritize building a resilient healthcare system, encouraging risk communication, and engaging the community in order to combat the Mpox outbreak in the Eastern DRC fragile conflict zones.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"20 ","pages":"Article 101012"},"PeriodicalIF":4.1,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143621404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rapid serotype-independent differential detection of biofilm-positive and biofilm-negative Salmonella using Fourier transform infrared biotyping","authors":"Asmita Shrestha,&nbsp;Smriti Shringi,&nbsp;Devendra H. Shah","doi":"10.1016/j.onehlt.2025.101004","DOIUrl":"10.1016/j.onehlt.2025.101004","url":null,"abstract":"<div><div>Foodborne illnesses caused by <em>Salmonella</em> represent a global one health challenge, with biofilm-forming strains exhibiting enhanced public health risks due to their ability to persist due to resistance to antimicrobial agents, disinfectants, and environmental stresses. While food-safety and public health investigation primarily focus on <em>Salmonella</em> identification and source tracing, they often overlook the biofilm-forming capacity of isolates, limiting their predictive value for risks posed by biofilm producing <em>Salmonella</em>. This study assessed fourier transform infrared (FTIR) biotyping for rapid serotype-independent differentiatial detection of biofilm-positive (BFP) from biofilm-negative (BFN) <em>Salmonella</em>. A total of 270 <em>Salmonella</em> strains representing 12 common serotypes were classified using three conventional biofilm assays (congo red and coomassie brilliant blue agar test, calcofluor test, and tube test) into true BFP (<em>n</em> = 80), true BFN (<em>n</em> = 64), and uncertain (<em>n</em> = 59) biofilm producers. Biofilm production for each group was also assessed with a microtiter plate assay. FTIR biotyping was applied to a subset of 115 strains (61 BFP, 54 BFN). Using spectral windows of 1180–1050 cm⁻¹ and 1400–1200 cm⁻¹, FTIR biotyping accurately differentiated BFP from BFN strains with 93.4 % sensitivity, 83.3 % specificity, and 88.6 % overall accuracy. FTIR biotyping differentiated 59 strains with uncertain biofilm status into BFN (<em>n</em> = 45) and BFP (<em>n</em> = 14). FTIR biotyping provides a rapid, sensitive and specific method for detection of biofilm-forming <em>Salmonella</em> strains. Incorporating FTIR biotyping for biofilm detection in current <em>Salmonella</em> surveillance and source-tracing protocols can enhance food safety risk assessments and improve <em>Salmonella</em> outbreak prevention.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"20 ","pages":"Article 101004"},"PeriodicalIF":4.1,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143579565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One Health implementation: A systematic scoping review using the Quadripartite One Health Joint Plan of Action","authors":"Adriana Milazzo ,&nbsp;Jingwen Liu ,&nbsp;Priyanka Multani ,&nbsp;Sandra Steele ,&nbsp;Elizabeth Hoon ,&nbsp;Anne-Lise Chaber","doi":"10.1016/j.onehlt.2025.101008","DOIUrl":"10.1016/j.onehlt.2025.101008","url":null,"abstract":"<div><h3>Background</h3><div>One Health (OH) recognizes the interconnectedness of humans, animals, and their shared environment and mobilizes multiple sectors to achieve sustainable and optimal health outcomes. We synthesized current OH implementations at global, regional, national, and local community levels using the OH Joint Plan of Action (OH JPA) developed to enhance best practices in OH implementation.</div></div><div><h3>Methods</h3><div>We applied the OH JPA Theory of Change, supported by three pathways mapped out across six action tracks to guide our review. Searches were conducted in PubMed, Embase and Scopus. Eligibility of studies was based on implementation of OH undertaken across two or more sectors within the human-animal-environment interface. Selection was guided by the PRISMA-ScR.</div></div><div><h3>Results</h3><div>Of the 54 studies, 77 unique programs reported OH implementations, and of these, 42 (54.5 %) involved human and animal sectors only. No studies involved the environment sector and its impact on human-environment or animal-environment. The majority (90.9 %) of programs incorporated at least one aspect of policy, legislation, advocacy and financing (Pathway 1). Capacity development, community engagement, multisectoral coordination, collaboration or communication was identified in 96.1 % of programs (Pathway 2). Data, evidence and knowledge featured in 60 % of OH initiatives (Pathway 3).</div></div><div><h3>Conclusion</h3><div>Pathway 2 was the most engaged pathway building the foundation for OH implementation and action. There is opportunity for further growth concerning community engagement, monitoring and evaluation strategies with enhanced future investment for implementation of community-centric and risk-based solutions. Furthermore, it is important to foster better understanding of environmental issues and to build capacity for the environment sector to be better represented in the implementation of OH.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"20 ","pages":"Article 101008"},"PeriodicalIF":4.1,"publicationDate":"2025-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143611734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}