One Health最新文献

{"title":"Knowledge, attitudes, and practices of Native Americans in northern California regarding ticks and tick-borne diseases","authors":"Patricia Torres ,&nbsp;Elizabeth F. Pienaar ,&nbsp;Michelle A. Ritchie ,&nbsp;Mourad W. Gabriel ,&nbsp;Michael J. Yabsley","doi":"10.1016/j.onehlt.2025.100976","DOIUrl":"10.1016/j.onehlt.2025.100976","url":null,"abstract":"<div><div>Reports of tick-borne diseases (TBDs) are increasing worldwide, particularly in North America where a diversity of endemic and exotic tick species and pathogens occur. Native American populations have unique outdoor cultural and occupational practices that may impact their exposure to ticks, yet this risk remains understudied in the context of TBD. To address this gap, we examined knowledge, attitudes, and practices regarding ticks and TBDs among Native American communities in Humboldt County, California. We conducted semi-structured interviews with participants, who represented various tribes, at a cultural gathering. Cultural practices intertwined closely with outdoor activities (e.g., ceremonies, dances), potentially influencing local tick exposure patterns. Most research participants had been bitten by ticks and reported tick exposure by children and pets. Research participants demonstrated low knowledge about ticks and TBDs, as well as low levels of risk perceptions pertaining to TBDs. Research participants most commonly conducted tick checks after outdoor activity, wore long-sleeved clothing outdoors, and used homeopathic remedies or essential oils to prevent exposure to ticks and TBDs. Culturally appropriate outreach and education initiatives are needed to address TBD risk among Native American communities. Our study lays the groundwork for future research on the intersection of cultural practices and tick exposure, with implications for public health interventions that are tailored to the needs of indigenous populations.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"20 ","pages":"Article 100976"},"PeriodicalIF":4.1,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787543/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143080752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a zoonotic influenza distribution assessment and ranking system (ZIDAR): Technical application in Nepal to support cross-sectoral risk-based surveillance","authors":"Adam Charette-Castonguay ,&nbsp;Dipendra Gautam ,&nbsp;Binay Shrestha ,&nbsp;Hemant Chandra Ojha ,&nbsp;Barun Kumar Sharma ,&nbsp;Mukul Upadhayaya ,&nbsp;Sujan Rana ,&nbsp;Roshika Shrestha ,&nbsp;Lok Bandu Chaudhary ,&nbsp;Bhawana Kandel ,&nbsp;Rudra Prasad Marasini ,&nbsp;Sharmila Chapagain ,&nbsp;Tulsi Ram Gompo ,&nbsp;Surendra Karki ,&nbsp;Apsara Poudel ,&nbsp;Saugat Shrestha ,&nbsp;Avinash Sunny Kayastha ,&nbsp;Arun Kumar Govindakarnavar ,&nbsp;Reuben Samuel ,&nbsp;Allison Gocotano ,&nbsp;Ricardo J. Soares Magalhães","doi":"10.1016/j.onehlt.2025.100975","DOIUrl":"10.1016/j.onehlt.2025.100975","url":null,"abstract":"<div><div>Zoonotic influenza poses a significant public health concern to agricultural industries, food security, wildlife conservation, and human health. Nations situated along migratory bird flyways and characterised by dense populations of livestock and humans, and low biosecurity of production animal value chains are particularly vulnerable to zoonotic influenza outbreaks. While spatial risk assessments have been used to map vulnerable areas, their applicability across multiple sectors has been so far limited. Here, we introduce the development and application of a Zoonotic Influenza Distribution and Ranking (ZIDAR) framework to identify areas highly suitable for zoonotic influenza transmission across multiple exposure interfaces and to measure the importance of associated risk factors. The development of ZIDAR involves a seven-step approach distributed across an initial expert consultation stage followed by a technical modelling stage. The expert consultation stage aims to define interfaces of exposure across human, livestock and wildlife, identification of associated risk factors for each of the identified interfaces and a prioritisation activity to define weights for the interfaces and associated risk factors. This is then followed by a technical phase involving model building, model structure validation, data gathering and assessment of model performance. The model development and performance assessment steps of the technical stage includes a model calibration step to maximise model fitness with regards to wildlife and animal interfaces by finding pareto-efficient sets of weights for risk factors. We applied the ZIDAR framework in Nepal and the resulting model structure enabled the identification of hotspot areas where the risk of transmission is more significant across multiple interfaces simultaneously. The ZIDAR Nepal model's predictive accuracy, determined by the area under the receiver operating characteristic curve, demonstrated strong performance: 0.87 and 0.85 for the wildlife and animal components, respectively. The ZIDAR framework presented here provides valuable insights to enable the formulation of comprehensive One Health surveillance programs and inform targeted and effective interventions to bolster pandemic preparedness strategies.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"20 ","pages":"Article 100975"},"PeriodicalIF":4.1,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143174832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular assessment of oyster microbiomes and viromes reveals their potential as pathogen and ecological sentinels","authors":"Jordan R. Walker ,&nbsp;Dennis A. Bente ,&nbsp;Megan T. Burch ,&nbsp;Filipe M. Cerqueira ,&nbsp;Ping Ren ,&nbsp;Jessica M. Labonté","doi":"10.1016/j.onehlt.2025.100973","DOIUrl":"10.1016/j.onehlt.2025.100973","url":null,"abstract":"<div><div>Oyster aquaculture world-wide is a booming industry that can provide many benefits to coastal habitats, including economic, ecosystem-level, and cultural benefits. Oysters present several risks for human consumption, including transmission of parasites, and bacterial and viral pathogens. Oyster microbiomes are well-defined, but their connection to the incidence of pathogens, humans or others, is unclear. Furthermore, viruses associated with oysters are largely unknown, and their connection to humans, animals, and ecosystem health has not been explored. Here, we employed a One Health framework and modern molecular techniques, including 16S rRNA amplicon and metagenomic sequencing, to identify links between changes in the microbial and viral communities associated with oysters and the incidence of pathogens detected in oyster tissues and their surrounding environments. In addition, we adapted the BioFire® FilmArray®, commonly used in hospitals, to determine the presence of human pathogens within the sampled oysters. We detected known human pathogens in 50 % of the oysters tested. Within the genomic datasets, we noted that pathogens of humans, animals, and plants in oysters were shared with the nearby water and sediments, suggesting a sink–source dynamic between the oysters and their surroundings. 16S rRNA gene analysis revealed that while oysters share common microbial constituents with their surrounding environments, they enrich for certain bacteria such as Mycoplasmatales, Fusobacteriales, and Spirochaetales. On the contrary, we found that oyster viromes harbored the same viruses in near equal relative abundances as their surrounding environments. Our results show how oysters could be used not only to determine the risk of human pathogens within coastal estuaries but also how oyster viruses could be used as ecosystem-level sentinels.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"20 ","pages":"Article 100973"},"PeriodicalIF":4.1,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11786891/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143080755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Monitoring for respiratory viruses among wild canids, Texas","authors":"Lyudmyla V. Marushchak ,&nbsp;Laura A. Pulscher ,&nbsp;Judith U. Oguzie ,&nbsp;Diego B. Silva ,&nbsp;Kenneth A. Waldrup ,&nbsp;Douglas M. Watts ,&nbsp;Gregory C. Gray","doi":"10.1016/j.onehlt.2025.100974","DOIUrl":"10.1016/j.onehlt.2025.100974","url":null,"abstract":"<div><div>The cross-species transmission of respiratory viruses such as SARS-CoV-2 and avian influenza underscores the need for novel respiratory virus surveillance at the human-animal interface. In this 2023 pilot study we examined oral and rectal swab samples from 15 deceased wild animals for novel respiratory viruses. We used virus molecular techniques, culture and next-generation nucleotide sequencing to search for and characterize viruses in the <em>Coronaviridae</em> and <em>Orthomyxoviridae</em> families. Through these activities we detected and characterized one canine coronaviruses (CCoVs) each from a gray fox (<em>Urocyon cinereorgenteus</em>) and a feral dog (<em>Canis lupus familiaris</em>). The gray fox CCoV sequence clustered with other CCoVs reported in other canids from other regions of the world. The feral dog CCoV sequence was closely related to CCoVs reported in Brazil and the United Kingdom. This pilot study demonstrated the usefulness of a noninvasive monitoring approach in detecting and characterizing respiratory viruses among wild canids.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"20 ","pages":"Article 100974"},"PeriodicalIF":4.1,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787532/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143080784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genomic and resistome analysis of Salmonella enterica isolates from retail markets in Yichun city, China","authors":"Xiaowu Jiang ,&nbsp;Abubakar Siddique ,&nbsp;Li Chen ,&nbsp;Lexin Zhu ,&nbsp;Haiyang Zhou ,&nbsp;Li Na ,&nbsp;Chenghao Jia ,&nbsp;Yan Li ,&nbsp;Min Yue","doi":"10.1016/j.onehlt.2025.100967","DOIUrl":"10.1016/j.onehlt.2025.100967","url":null,"abstract":"<div><div>Nontyphoidal <em>Salmonella</em> (NTS) causes global outbreaks of foodborne disease. The main source of <em>Salmonella</em> for humans is animal-borne foods; however, the monitoring of <em>Salmonella</em> in the food chain via genomic platforms was limited in China. This study evaluated the prevalence, resistome, and virulome diversity of <em>Salmonella</em> strains identified from pork, retail environment, aquatic products, and poultry eggs of retail markets in Yichun city, Jiangxi province. The overall incidence of <em>Salmonella</em> was 9.4 %, with a higher contamination rate observed in pork at 13.5 %, followed by the retail environment at 7.69 %. The genomic analysis of the isolates revealed a total of fifteen distinct serovars, with serovar Enteritidis being the most prevalent (64.3 %). The phenotypic resistance analysis conducted by the broth microdilution method, revealed that 81.12 % of the isolates exhibited multidrug resistance (MDR), with high resistance to trimethoprim/sulphonamides (100 %), followed by tetracycline (99.3 %) and streptomycin (99.3 %). Genotypic analysis of antimicrobial resistance identified 80 antimicrobial-resistant genes (ARGs), with <em>mdf(A)</em>, <em>aph(3′)-Ib</em>, <em>tet(A)</em>, <em>dfrA12</em>, <em>floR</em>, <em>bla</em>_{<em>TEM-1B</em>}, <em>qnrS3</em>, and <em>sul2,</em> conferring resistance to different antimicrobial classes, being the predominant ARGs. Additionally, forty ESBL genes, particularly critical genes such as <em>bla</em>_CTX-M and <em>bla</em>_NDM-1, were also identified in <em>Salmonella</em> isolates. The <em>IncR</em>, <em>IncFIB (K)</em>, and <em>IncX1</em> plasmid replicons were widely prevalent and served as significant reservoirs of horizontally acquired foreign genes. Moreover, key virulence genes such as <em>cdtB</em>, <em>lpf</em> and <em>sef</em> were also detected, in addition to <em>Salmonella</em> pathogenicity islands SPI-1 and SPI-2. This study reveals the prevalence of multidrug-resistant and virulent strains of <em>Salmonella</em> serovars in the markets of Yichuan city, posing a risk of human infections. The gained knowledge provided essential baseline information that may be utilized for regular tracking of MDR <em>Salmonella</em> transmission in the food chain to minimize potential future outbreaks.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"20 ","pages":"Article 100967"},"PeriodicalIF":4.1,"publicationDate":"2025-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143175760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Subtle genomic differences in Klebsiella pneumoniae sensu stricto isolates indicate host adaptation","authors":"Bridget O'Brien ,&nbsp;Alla Yushchenko ,&nbsp;Jinha Suh ,&nbsp;Dongyun Jung ,&nbsp;Zhangbin Cai ,&nbsp;Ngoc Sang Nguyen ,&nbsp;Makeda Semret ,&nbsp;Simon Dufour ,&nbsp;Séamus Fanning ,&nbsp;Jennifer Ronholm","doi":"10.1016/j.onehlt.2025.100970","DOIUrl":"10.1016/j.onehlt.2025.100970","url":null,"abstract":"<div><div><em>Klebsiella pneumoniae sensu stricto</em> (KpI) is an opportunistic pathogen capable of residing as a commensal in both human and bovine intestinal tracts and can cause serious systemic infections in humans and severe clinical mastitis in dairy cattle. It is unclear what role zoonotic and anthroponotic transmission play in the dissemination of KpI. In this study, we use a comparative genomic approach to identify differences between KpI associated with disease in humans and cattle and aimed to identify any potential genetic barriers limiting transmission of KpI between these two hosts. A total of 128 KpI strains (bovine <em>n</em> = 65; human <em>n</em> = 63) were whole genome sequenced and human and bovine strains were compared based on phylogenomics, the pangenome, mobile genetic elements, and differential gene abundance. No obvious phylogenomic differentiation was observed between isolates from these hosts. However, subtle genetic differences exist between bovine and human KpI which likely reflect environmental adaptation to different host niches, including a higher representation of gene clusters encoding ferric citrate uptake transporters, as well as histidine, arginine, and lactose utilization pathways in bovine isolates. These gene clusters may be positively selected due to the unique metabolic environment of the mammary gland, where lactose, citrate-bound iron, and amino acids like histidine and arginine provide growth advantages for KpI during mastitis. Overall, our study identified no obvious genetic barriers to zoonotic transmission of KpI within the dairy environment and provides insight into the development of host-specific therapeutic options for KpI infections in humans and bovine.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"20 ","pages":"Article 100970"},"PeriodicalIF":4.1,"publicationDate":"2025-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787494/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143080797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and antimicrobial resistance of Campylobacter jejuni and Campylobacter coli over time in Thailand under a One Health approach: A systematic review and meta-analysis","authors":"Doan Hoang Phu ,&nbsp;Tuempong Wongtawan ,&nbsp;Truong Thanh Nam ,&nbsp;Dinh Bao Truong ,&nbsp;Naparat Suttidate ,&nbsp;Juan Carrique-Mas ,&nbsp;Niwat Chansiripornchai ,&nbsp;Conny Turni ,&nbsp;Patrick J. Blackall ,&nbsp;Thotsapol Thomrongsuwannakij","doi":"10.1016/j.onehlt.2025.100965","DOIUrl":"10.1016/j.onehlt.2025.100965","url":null,"abstract":"<div><div><em>Campylobacter</em> spp. are major food-borne zoonotic pathogens impacting food safety worldwide. Thailand is one of the countries facing with a significant burden of <em>Campylobacter</em> infections and is recognized as a hotspot of AMR. Our study applied a systematic review and meta-analysis, using a One Health perspective, to investigate the prevalence and AMR of <em>Campylobacter jejuni</em> (<em>C. jejuni</em>) and <em>Campylobacter coli</em> (<em>C. coli</em>) over time in Thailand, from 1985 to 2023. Based on the PRISMA guidelines, a literature search using PubMed, ScienceDirect, and Google Scholar to identify the articles reporting prevalence, sequence types (STs), antimicrobial susceptibility, and resistance genes of <em>Campylobacter</em> spp. in humans, animals, food, and environmental samples was performed. Eighty-one articles were retrieved for systematic review, with 33 reporting <em>Campylobacter</em> spp. prevalence and 20 containing AMR data collected for meta-analysis. The highest prevalence of <em>C. jejuni</em> was found in chickens (43.6 %) and chicken products (31.4 %), followed by ducks (16.7 %), the general human population with diarrhea (15.9 %), children with diarrhea (10.7 %). <em>C. coli</em> was also prevalent in chickens (12.6 %) and chicken products (10.4 %). <em>C. jejuni</em> prevalence decreased by 14.8 % among children with diarrhea (<em>p</em> = 0.006), but increased by 16.7 % in chicken products (<em>p</em> = 0.007). Sixty-two STs were identified, with ST 574, ST 1075, ST 51 being the most prevalent STs recorded. Five STs, including ST 50, ST 51, ST 354, ST 464, and ST 574, were reported in both humans and chickens. The AMR levels were highest against quinolones, ranging 75.4 %–94.8 % in human-related categories and 71.6 %–88.7 % in chicken-related categories. Notably, ciprofloxacin-resistant and nalidixic acid-resistant <em>C. jejuni</em> strains collected from chickens increased by 11.9 % (<em>p</em> = 0.004) and 16.1 % (<em>p</em> = 0.027), respectively. Thirteen resistance genes/mutations were reported, with the phenotypic resistance linked to <em>gyrA</em> mutations and <em>tet</em>(O) genes. The high prevalence and increasing trend of AMR in <em>C. jejuni</em> and <em>C. coli</em> underscore the critical need for One Health surveillance to address the rising AMR challenge posed by these pathogens in Thailand.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"20 ","pages":"Article 100965"},"PeriodicalIF":4.1,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11782884/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143080792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health-related dimensions of fishers for sustainable commercial fisheries in the Atlantic Gulf of Guinea: Ecological and social assessments","authors":"Isa Oalekan Elegbede ,&nbsp;Saud. M Al Jufaili ,&nbsp;Toheeb Lekan Jolaosho ,&nbsp;Babalola Tesleem ,&nbsp;Awe Folalu Adekunle ,&nbsp;Olarinmoye Oluwatosin Modupe ,&nbsp;Salisu Monsuru Adekunle ,&nbsp;Adedeji-Adenola Halimat","doi":"10.1016/j.onehlt.2025.100972","DOIUrl":"10.1016/j.onehlt.2025.100972","url":null,"abstract":"<div><div>Health considerations are seldom integrated into non-state voluntary sustainability certification standards, despite industrial fishing being one of the most hazardous occupations, often resulting in significant health risks for fishers. These challenges not only affect individual fishers but also have broader implications for the socio-ecological sustainability of fisheries. This study explores the effects of certification programs on industrial fishing activities and their health and safety dimensions within a socio-ecological framework, focusing on the Atlantic shrimp fishery in Nigeria. A mixed-methods approach was employed, combining qualitative and quantitative data collection techniques. Data were gathered from experienced employees of Friend of the Sea (FOS) certified and non-certified (Business-as-Usual, BAU) industrial fisheries through questionnaires, complemented by semi-structured interviews with selected key informants. The study examines the relationships between demographic variables, health-related indicators, and certification program participation using multivariate analyses, including Chi-square and standard logistic regression models. The findings revealed that fishers participating in the FOS certification program reported better health conditions, lower risks, and higher insurance coverage levels than their BAU counterparts. Certified fishers had greater access to sick leave and annual days off and were more likely to be physically fit for work. Conversely, fishers in the BAU group faced significantly higher health risks and casualty rates during fishing operations. These results underscore the critical role of health-focused certification programs, such as FOS, in improving the well-being of fishers, thereby enhancing the socio-ecological sustainability of Nigeria's shrimp fishing industry. The study highlights the importance of integrating health considerations into sustainability certification standards. By prioritizing fisher's safety and well-being, such programs contribute to the sustainable management of fisheries resources and environmental protection, aligning with the principles of the One Health framework.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"20 ","pages":"Article 100972"},"PeriodicalIF":4.1,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143175761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emerging multi-drug resistant and extended-spectrum β-lactamase (ESBL)-positive enterotoxigenic E. coli (ETEC) clones circulating in aquatic environments and in patients","authors":"Enrique Joffré ,&nbsp;Alberto J. Martín-Rodríguez ,&nbsp;Annie Justh de Neczpal ,&nbsp;Astrid von Mentzer ,&nbsp;Åsa Sjöling","doi":"10.1016/j.onehlt.2025.100968","DOIUrl":"10.1016/j.onehlt.2025.100968","url":null,"abstract":"<div><div>Diarrheal disease pathogens often spread through water-borne routes. Enterotoxigenic <em>Escherichia coli</em> (ETEC) is a major bacterial agent causing diarrheal disease in children, adults, and travelers in endemic areas. In addition, ETEC is responsible for outbreaks of water and food-borne gasteroenteritis globally, ETEC isolates also show robust survival capacity in various environmental settings, including aquatic environments.</div><div>During the last decade, studies of ETEC isolates have indicated a rapid increase in multi-drug resistant and extended-spectrum β-lactamase (ESBL)-positive human-specific ETEC strains. These have been found in both environmental water sources and human patients, warranting the urgent need for focused monitoring of antibiotic resistance development in ETEC.</div><div>Whole genome sequencing (WGS) of isolates from environmental, animal, and human sources enables in silico surveillance of emerging pathogenic and multi-drug resistant strains. This method allows for re-analysis of genomic data, aiding in identification of new variants of pathogenic clones.</div><div>By integrating data from diverse sources inclusing sequenced isolates, we found that certain ETEC clonal lineages e.g., those expressing certain toxin-colonization factor profiles including STp/CS6, LT STh/CS2 + CS3, and LT STh/CFA/I are more at risk to develop multi-drug resistance than other ETEC lineages. Comparizon of multi-locus sequence types from papers with WGS data indicated ST182, ST4, ST2332 and new ST types to be emerging multi-drug resistant ETEC.</div><div>We conclude that further studies on sequenced ETEC/<em>E. coli</em> genomes are needed to enhance our understanding of the dynamics of ETEC evolution, and the relation of virulence and resistance profiles in both environmental and clinical isolates.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"20 ","pages":"Article 100968"},"PeriodicalIF":4.1,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11786893/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143080736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancing green recovery: Integrating one health in sustainable wildlife management in the Asia-Pacific Indigenous People and Local Communities","authors":"Nareerat Sangkachai ,&nbsp;Anuwat Wiratsudakul ,&nbsp;Delia G. Randolph ,&nbsp;Maxine Whittaker ,&nbsp;Acty George ,&nbsp;Martin R. Nielsen ,&nbsp;Nicholas Hogarth ,&nbsp;Dirk U. Pfeiffer ,&nbsp;Carsten Smith-Hall ,&nbsp;P.O. Nameer ,&nbsp;Latiffah Hassan ,&nbsp;Gautam Talukdar ,&nbsp;Tien Ming Lee ,&nbsp;Vinod B. Mathur ,&nbsp;Innocent B. Rwego ,&nbsp;James Compton ,&nbsp;Manon Mispiratceguy ,&nbsp;Jianbin Shi ,&nbsp;Amanda E. Fine ,&nbsp;Illias Animon ,&nbsp;Sarin Suwanpakdee","doi":"10.1016/j.onehlt.2025.100969","DOIUrl":"10.1016/j.onehlt.2025.100969","url":null,"abstract":"<div><div>Wildlife (in this paper: wild animals) deliver a crucial range of ecosystem services on human health and livelihood, particularly in Indigenous People and Local Communities (IPLCs). ‘One Health’ extends beyond just health; it also includes a comprehensive framework that can address wildlife and biodiversity conservation to enhance the well-being of humans, animals, and the environment with multisectoral collaboration. Therefore, integrating One Health principles into wildlife management was suggested in this review to improve the quality of life by reducing poverty, improving food security, and preventing zoonotic diseases in IPLCs. The relationship between wildlife interactions and the emergence of pathogens that can be transmitted between wild animals, domestic and production animals, and humans underscores the need to incorporate a One Health approach to mitigate risk. This integration will also contribute to conserving wild animals and their habitats and biodiversity for ecosystem balance. This review highlights the importance of One Health in supporting sustainable wildlife management to achieve a green recovery through policies and actions based on global and national regulatory frameworks, development of local policies with community engagement, risk assessment and communication, sustainable wildlife use practices, and conducting research and innovation. Monitoring and analyzing data on supply chains and economic values can serve as a decision-support tool for sustainability wildlife management. A theory of change for sustainable wildlife management and enhancing human well-being is proposed using the One Health approach. All these activities must respect local cultures and traditions, ensuring that One Health and community-based approaches effectively benefit local communities.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"20 ","pages":"Article 100969"},"PeriodicalIF":4.1,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11782897/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143080719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}