One Health最新文献

{"title":"Domestic animals and hygiene on infants' risk of contact and exposure to animal faeces in urban neighbourhoods in Kenya: A mixed methods cohort study","authors":"Innocent K. Tumwebaze ,&nbsp;Mark Krysan ,&nbsp;Phylis J. Busienei ,&nbsp;Sheillah Simiyu ,&nbsp;Blessing Mberu ,&nbsp;Daniel K. Sewell ,&nbsp;Kelly K. Baker","doi":"10.1016/j.onehlt.2025.101217","DOIUrl":"10.1016/j.onehlt.2025.101217","url":null,"abstract":"<div><div>Contact with animals or their faeces could expose infants to zoonotic pathogens associated with diarrheal infections in infants. This study investigated the risk of infants' exposure to domestic animals and their faeces in low- and middle-income urban neighbourhoods in Kenya. A total of 275 caregivers with infants aged 0–12 months from low- income and middle-income neighbourhoods in Nairobi and Kisumu were enrolled in a cohort prospective study and completed the survey. Of these, 136 belonged to low-income and 139 to middle-income neighbourhoods. To ensure balanced recruitment of infants in each neighbourhood, community health promoters who provided a listing of caregivers and their infants aged 0–12 months to form the sampling frame. Recruitment was based on the target for each infant age cluster. Negative Binomial, Zero-Inflated Poisson (ZIP), and Zero-Inflated Negative Binomial (ZINB) regression models were used to test for the rate of infant contact (per hour) with animals and animal faeces and logistic regression for infant exposure to surfaces contaminated with animal faeces. Bayes factors were used for model selection. Overall, 27.9 % of the studied low-income neighbourhood households and 30.9 % of those in middle-income neighbourhoods owned domestic animals. Infants in households who owned cats had a 109 % increase (95 %CI = 59 %, 173 %) in contact compared to non-cat owning households. There was a 22 % decrease (95 %CI = 7 %, 42 %) in infant contact with non-feline animals compared to households that did not own them. The rate of contact with animals, animal faeces, or surfaces polluted by animal faeces increased with age. Full penning of household owned animals reduced the rate of infant contact with animal faeces by 93 % (95 %CI = 16 %, 99.7 %), compared to no penning, and reduced the odds of infant contact with a contaminated surface by 97 % (95 %CI = 42 %–99.9 %), compared to no penning. Self-reported animal faeces disposal practices were not significantly associated with a reduced rate of infant contact with animal faeces or touching surfaces contaminated by animal faeces. The study findings infants in households that owned cats have an increased contact with them while full penning of domestic animals is associated with reduced risk of exposure to animal faeces or contaminated surfaces.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"21 ","pages":"Article 101217"},"PeriodicalIF":4.5,"publicationDate":"2025-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145104403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Naegleria fowleri and the future of surveillance: A one-health call to action","authors":"Anushka Reddy Marri ,&nbsp;Davidson H. Hamer ,&nbsp;Samendra Sherchan ,&nbsp;Kayoko Shioda","doi":"10.1016/j.onehlt.2025.101215","DOIUrl":"10.1016/j.onehlt.2025.101215","url":null,"abstract":"<div><div><em>Naegleria fowleri</em> causes primary amoebic meningoencephalitis (PAM), a rapidly fatal central nervous system infection acquired through nasal exposure to contaminated water. PAM cases are rare but increasingly reported across wider geographic areas and through emerging exposure routes in humans and animals. Environmental detections of <em>N. fowleri</em> are rising, yet surveillance remains sparse and is often triggered only after clinical cases are identified. This reactive approach delays risk mitigation and limits opportunities for prevention. Rising temperatures, inadequate water treatment, and shifting water use patterns may expand the organism's ecological range. This short communication advocates for proactive environmental and clinical surveillance of <em>N. fowleri</em> as a One Health priority. Drawing on global examples, we propose routine monitoring of high-risk water systems, standardization of detection protocols, and case notification requirements. Together with public education in vulnerable settings, these efforts can strengthen preparedness and improve outcomes for a preventable and nearly universally fatal infection.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"21 ","pages":"Article 101215"},"PeriodicalIF":4.5,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145104402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring human-to-food contamination potential: Genome-based analysis of diversity, toxin repertoire, and antimicrobial resistance of methicillin-resistant Staphylococcus aureus in United Arab Emirates retail meat","authors":"Ihab Habib ,&nbsp;Akela Ghazawi ,&nbsp;Mohamed-Yousif Ibrahim Mohamed ,&nbsp;Glindya Bhagya Lakshmi ,&nbsp;Rania Nassar ,&nbsp;Stefan Monecke ,&nbsp;Ralf Ehricht ,&nbsp;Danesh Moradigaravand ,&nbsp;Dean Everett ,&nbsp;Richard Goering ,&nbsp;Mushtaq Khan ,&nbsp;Abiola Senok","doi":"10.1016/j.onehlt.2025.101216","DOIUrl":"10.1016/j.onehlt.2025.101216","url":null,"abstract":"<div><div>Methicillin-resistant <em>Staphylococcus aureus</em> (MRSA) has moved beyond healthcare settings and is increasingly documented in food, yet genomic data from the Arabian Peninsula are scarce. This study aimed to characterize the genomic diversity, antimicrobial-resistance (AMR), and virulence repertoire of MRSA in retail red meat sold in Dubai, United Arab Emirates (UAE), and to evaluate evidence for potential human-to-food transmission. In a cross-sectional survey (September 2024 – February 2025), 140 red-meat samples (beef, mutton, camel) were collected from supermarket chains. Fifty-one MRSA isolates were confirmed by multiplex PCR and phenotypic testing. Short-read whole-genome sequencing was followed by bioinformatic characterization of the isolates for clonal complex (CC) multilocus sequence typing (ST), <em>spa</em> typing, SCC<em>mec</em> assignment, AMR and virulence genes identification, plasmid-replicon detection, and core-genome phylogeny. Genotype, meat commodity, and products' origin associations were statistically assessed. Eight sequence types were detected; CC5-ST6 (27.5 %) and CC8-ST789 (23.5 %) predominated. SCC<em>mec</em> IV and V accounted for 82.3 % of genomes, and no livestock-associated CC398 was found. CC5/ST6-t304 and CC8-t091 comprised 47 % of isolates but showed no association with meat type (<em>p</em> = 0.451). Core-genome analysis split the collection into six clusters with shallow branch lengths, signaling recent clonal expansion across local and imported meat products. All genomes carried the methicillin resistance <em>mecA</em> gene plus a median of five additional resistance genes; 41 % carried multidrug-resistant determinants. Classical enterotoxin genes occurred in 80.4 % of isolates, and Panton–Valentine leukocidin genes in 27.5 %, mainly within CC8 and CC22. Distinct plasmid backbones—RepA_N–RepL–Rep_trans in CC5-ST6 and Inc18–Rep3 in CC8-ST789—were associated with lineage-specific AMR profiles. Retail red meat in the UAE is contaminated by clinically important, community-associated MRSA clones, likely introduced via human handling rather than animal reservoirs. Genomic surveillance at the human-food interface can guide regional One Health policies and help curb foodborne antimicrobial resistance dissemination.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"21 ","pages":"Article 101216"},"PeriodicalIF":4.5,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145104404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Composite function and Biomod2 for evaluating the influence of climate change on the distribution of Aedes aegypti and Aedes albopictus in China","authors":"Jianjun Xu ,&nbsp;Rulin Wang ,&nbsp;Zhenhan Mo ,&nbsp;Han Zhang ,&nbsp;Yujing Zhang","doi":"10.1016/j.onehlt.2025.101212","DOIUrl":"10.1016/j.onehlt.2025.101212","url":null,"abstract":"<div><div>Vector-borne diseases transmitted by <em>Aedes,</em> including dengue fever, Chikungunya fever, Zika virus, and yellow fever, represent major global public health threats. This study utilized the Biomod2 modeling framework, incorporating 19 bioclimatic variables, to simulate the current and future geographical distributions of <em>Aedes aegypti</em> and <em>Aedes albopictus</em> in China under climate change scenarios (SSP2–4.5 and SSP5–8.5). The results indicated that under future climate scenarios, highly suitable regions for both <em>Aedes</em> would decrease in area, while moderately suitable regions would expand. The co-presence probability analysis revealed that highly suitable regions for both species would concentrate in southern and southeastern China, with notable areas in Yunnan, Guangxi, Guangdong, and Hainan. From current to 2090s, the centroid would shift to northeast under SSP2–4.5 and SSP5–8.5. For <em>Ae. aegypti</em>, the most important variables were isothermality (bio3, 44.05 %), precipitation of the wettest quarter (bio16, 27.87 %), and mean temperature of the coldest quarter (bio11, 22.4 %). For <em>Ae. albopictus</em>, the mean temperature of the coldest quarter (bio11, 54.12 %), annual precipitation (bio12, 22.76 %), and precipitation of the coldest quarter (bio19, 13.47 %) were most significant. These findings highlight the potential impacts of climate change on the distribution dynamics of dengue vectors and provide a basis for developing targeted surveillance and control strategies to mitigate future transmission risks.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"21 ","pages":"Article 101212"},"PeriodicalIF":4.5,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145104252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One health, one earth, one life: The overlooked role of veterinarians in the fight against COVID-19 and other public health emergencies in Italy","authors":"Sante Roperto ,&nbsp;Giovanni Di Guardo","doi":"10.1016/j.onehlt.2025.101207","DOIUrl":"10.1016/j.onehlt.2025.101207","url":null,"abstract":"<div><div>This essay explores the crucial and often overlooked role of veterinarians in managing and responding to pandemics. Despite their pivotal activities in protecting public health, veterinarians in Italy were largely absent from the media storytelling of the COVID19 pandemic, which was mostly focused on a hospital-centered perspective. Regretfully, we witness herein the occurrence of a similar situation within the media coverage in Italy of other public health emergencies, such as those caused by the highly pathogenic avian influenza A(H5N1) virus and by the West Nile virus. This article examines the asymmetry in professional representation during public health crises in Italy, thereby calling for a more inclusive approach to global health challenges, employing a One Health framework that acknowledges the connection between human, animal and environmental health. Within this framework, we also report how veterinarians contribute to food safety, zoonotic disease monitoring, epidemiological studies and ecosystem management, all of which are essential for pandemic prevention and response. Our goal in bringing these issues to light is to increase public awareness on the crucial role of veterinarians in public health risk analysis, communication and policy formulation, which will ultimately make society more resilient to potential pandemic threats in the future.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"21 ","pages":"Article 101207"},"PeriodicalIF":4.5,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145104253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrating One Health governance in China: Assessing structural implementation and operational entry points","authors":"Qi-yu Zhang ,&nbsp;Yan-Yan Zhang ,&nbsp;Jing-Shu Liu ,&nbsp;Xin-Chen Li ,&nbsp;Ze-Lin Zhu ,&nbsp;Xin-Yu Feng ,&nbsp;Le-Fei Han ,&nbsp;Chen-Di Zhu ,&nbsp;Hein-Min Tun ,&nbsp;Lian Zong ,&nbsp;Xiaoxi Zhang","doi":"10.1016/j.onehlt.2025.101209","DOIUrl":"10.1016/j.onehlt.2025.101209","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Background&lt;/h3&gt;&lt;div&gt;In China, despite the establishment of a top-level One Health framework to address the interconnected risks of zoonotic diseases, antimicrobial resistance (AMR), and environmental degradation, significant challenges persist in translating this vision into effective implementation. The country's large agricultural sector, dense population, and diverse ecosystems require coordinated governance across human, animal, and environmental health sectors. However, gaps remain in resource allocation, cross-sector coordination, and policy integration. This study evaluates China's One Health governance through four structural domains—Monitoring &amp; Evaluation, Intervention &amp; Response, Surveillance &amp; Early Warning, and Capacity Building—and four operational entry points—Technology, Information, Human Resources, and Finance. The aim is to identify strengths, gaps, and provide actionable recommendations for improvement.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;A qualitative approach was employed, involving 41 in-depth expert interviews, policy document analysis, and a systematic literature review. Interviews were conducted with stakeholders from public health, veterinary services, and environmental agencies, focusing on key domains of the One Health implementation. Data were thematically coded using NVivo 12.0 and analyzed using Grounded Theory. The results were cross-checked through intercoder reliability testing to provide actionable recommendations.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;While regular reporting mechanisms exist for Monitoring &amp; Evaluation across human, animal, and environmental health sectors, real-time assessments remain insufficient, limiting timely, multisectoral responses to emerging health risks. A tiered emergency system supports Intervention &amp; Response, but inefficiencies in cross-sector resource allocation and coordination hinder its effectiveness. In Surveillance &amp; Early Warning, fragmented data collection and interdepartmental silos across different health domains impede comprehensive and integrated risk monitoring. Despite existing Capacity Building programs, large-scale interdisciplinary exercises and continuous skill development opportunities remain scarce. Operationally, diagnostic technologies like polymerase chain reaction (PCR) and geographic information system (GIS) are available but unevenly distributed. Data-sharing mechanisms exist, but bureaucratic delays and inconsistent standards hinder integration. Workforce gaps, an aging cohort, and insufficient multidisciplinary training threaten the sustainability of the One Health framework. Operational budgets and personnel incentives remain inadequate, limiting the impact of financial investments.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusion&lt;/h3&gt;&lt;div&gt;Despite progress in policy and infrastructure, China faces critical gaps in One Health implementation, particularly in real-time monitoring, cross-sectoral coordination, data integration, workforce c","PeriodicalId":19577,"journal":{"name":"One Health","volume":"21 ","pages":"Article 101209"},"PeriodicalIF":4.5,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145117846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outbreak of highly pathogenic avian influenza a(H5N1) among house cats: A case series involving oseltamivir treatment","authors":"Jacob F. Gomez ,&nbsp;Ian G. Bemis ,&nbsp;Ismaila Shittu ,&nbsp;Gregory C. Gray ,&nbsp;Kristen K. Coleman","doi":"10.1016/j.onehlt.2025.101211","DOIUrl":"10.1016/j.onehlt.2025.101211","url":null,"abstract":"<div><div>We present a highly pathogenic avian influenza A(H5N1) outbreak among four domestic cats from the same household within close proximity to a dairy farm in Tulare, California – the epicenter of the H5N1 dairy cattle outbreaks in California, USA. We demonstrate that with early supportive care and treatment with oseltamivir, H5N1 is survivable in domestic cats, and that survivor cats may maintain high titers of neutralizing antibodies against H5N1 at least 3–4 months post recovery.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"21 ","pages":"Article 101211"},"PeriodicalIF":4.5,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145104270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between antibiotic resistance and air pollution and climate factors in China: A multivariable spatial-temporal analysis","authors":"Bingsong Li ,&nbsp;Xuemei Zhen ,&nbsp;Jiangfeng Ouyang ,&nbsp;Cecilia Stålsby Lundborg","doi":"10.1016/j.onehlt.2025.101204","DOIUrl":"10.1016/j.onehlt.2025.101204","url":null,"abstract":"<div><h3>Objective</h3><div>In this study, we aimed to identify the spatiotemporal variation of antibiotic resistance and its relationship with environmental factors (air pollution and climate factors) in China.</div></div><div><h3>Method</h3><div>The detection rate of <em>carbapenem-resistant Klebsiella pneumoniae</em> (CRKP) and <em>Escherichia coli</em> (CREC) in China from 2014 to 2022 was used to detect drug resistance. Air pollution factors include particulate matter and gaseous pollutants, and climate factors include temperature, precipitation and humidity. The spatial-temporal distributions and trend analyses were analyzed. Spatial autocorrelation analyses were performed to explore CRKP and CREC rates clustering. A geographically and temporally weighted regression model (GTWR) was adopted to analyze the relationship between antibiotic resistance rates and environmental factors.</div></div><div><h3>Result</h3><div>We found that PM_2.5, O_3, annual average temperature and annual cumulative precipitation primarily had positive impacts on both CREC and CRKP rates. SO₂, NO_2, CO and annual average humidity predominantly exerted negative impacts on both CREC and CRKP rates. Meanwhile, the influence of related factors on CREC and CRKP shows temporal and spatial heterogeneity. Both CREC and CRKP exhibited significant spatial aggregation, displaying High-High and Low-Low patterns. Trend analysis indicated an upward trend for both in the east-west direction and an inverted U-shape in the north-south direction.</div></div><div><h3>Conclusion</h3><div>It is important to pay attention to the impact of air pollution and climate factors on antibiotic resistance.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"21 ","pages":"Article 101204"},"PeriodicalIF":4.5,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145104264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Forest fragment size shapes Trypanosoma cruzi transmission and vector-host dynamics in eastern Colombia","authors":"Plutarco Urbano ,&nbsp;Carolina Hernández ,&nbsp;Luz H. Patiño ,&nbsp;Laura Vega ,&nbsp;Angie Ramírez ,&nbsp;Stivenn Gutiérrez ,&nbsp;Ricardo Herrera ,&nbsp;Davinzon Martínez ,&nbsp;Catalina Ariza ,&nbsp;Cielo Maritza León ,&nbsp;Camila González ,&nbsp;Juan David Ramírez","doi":"10.1016/j.onehlt.2025.101210","DOIUrl":"10.1016/j.onehlt.2025.101210","url":null,"abstract":"<div><div>Chagas disease, caused by the protozoan <em>Trypanosoma cruzi</em>, remains a major public health challenge in Latin America. Its transmission dynamics are tightly governed by ecological factors that influence vector–host interactions. Habitat fragmentation and land-use change disrupt sylvatic environments, forcing triatomine vectors to adapt to peridomestic settings, thereby increasing human–vector contact and modifying host availability. This study assesses how forest patch size influences <em>T. cruzi</em> transmission in three <em>Attalea butyracea</em>-dominated forest fragments of varying sizes (Canagüey: 109 ha, El Samán: 79 ha, La Dorada: 46 ha) in Casanare, eastern Colombia. Triatomines were collected using live-bait traps in 266 of the 330 sampled palms, and mammals were captured along edge and interior transects. A total of 2758 <em>Rhodnius prolixus</em> were collected, with the largest patch harboring the highest abundance. Among 1247 vectors analyzed by molecular methods, 91.48 % were infected with <em>T. cruzi</em>, exhibiting significant differences in parasite load among patches. Blood meal analysis using 12S rRNA gene amplicon sequencing revealed similar food sources across all vector developmental stages and forest sizes. Of the 147 mammals sampled, 6.8 % were infected in the smaller areas, while no infected mammals were found in the large forest, suggesting a higher parasite transmission in smaller forest fragments. These findings suggest that the forest fragments size influence the population concentration of triatomines and may facilitate increasing the risk of transmission of <em>T. cruzi</em>. Our results highlight the complex ecological interactions driving <em>T. cruzi</em> transmission and underscore the need for landscape-scale surveillance and targeted control measures to reduce the risk of parasite transmission in regions undergoing intense anthropogenic change.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"21 ","pages":"Article 101210"},"PeriodicalIF":4.5,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145104276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Apparent prevalence, lesion distribution and risk factors of bovine tuberculosis in cattle slaughtered at the Shashemene and Arsi Negelle municipal abattoirs, Ethiopia","authors":"Mohammed Desu ,&nbsp;Nigussu Fasil ,&nbsp;Rahmeto Abebe","doi":"10.1016/j.onehlt.2025.101200","DOIUrl":"10.1016/j.onehlt.2025.101200","url":null,"abstract":"<div><div>Bovine tuberculosis (bTB) is a chronic infectious disease caused by <em>Mycobacterium bovis</em>, primarily affecting cattle and presenting a zoonotic risk to humans. It adversely impacts milk and meat production, ultimately jeopardizing food security and livelihoods, particularly in developing countries like Ethiopia, where the disease is endemic. This cross-sectional study, conducted from January to December 2023, aimed to estimate the apparent prevalence of bTB, assess the distribution of lesions, and identify associated risk factors among cattle slaughtered at two municipal abattoirs. The study systematically examined the carcasses of 648 cattle. The results revealed an overall apparent prevalence of bTB of 6.2 % (95 % CI: 4.4 % - 8.3 %), with no significant difference observed between the two abattoirs (<em>p</em> &gt; 0.05). The highest proportion of TB lesions (48.8 %) was identified in the lungs and associated lymph nodes, followed by the mesenteric lymph nodes and livers (29.3 %), and the lymph nodes of the head (21.9 %). Multivariable logistic regression model identified breed and body condition scores as significant risk factors for the apparent prevalence of bTB. Specifically, crossbred cattle were found to be 2.8 times more likely to exhibit TB lesions than Zebus. Additionally, cattle in poor body condition were 8.4 times more likely to show TB lesions compared with those in good condition. These findings highlight the widespread occurrence of bTB among cattle, particularly in crossbred and poorly conditioned animals, with both respiratory and gastrointestinal tract involvement in the disease's spread. The study underscores the urgent need for enhanced control and prevention strategies against bTB in the region.</div></div>","PeriodicalId":19577,"journal":{"name":"One Health","volume":"21 ","pages":"Article 101200"},"PeriodicalIF":4.5,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145104258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}