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Real-time frame-registered resonant fluorescence scanning laser ophthalmoscopy for quantifying static and dynamic cellular properties in the mouse retina: publisher's note.
IF 3.1 2区 物理与天体物理
Optics letters Pub Date : 2025-03-15 DOI: 10.1364/OL.560030
Tianqi Song, Yao Wang, Yuxiang Zhou, Mingliang Zhou, Yanhong Ma, Donghan Ma, Jia Qu, Jinyi Zhang, Pengfei Zhang
{"title":"Real-time frame-registered resonant fluorescence scanning laser ophthalmoscopy for quantifying static and dynamic cellular properties in the mouse retina: publisher's note.","authors":"Tianqi Song, Yao Wang, Yuxiang Zhou, Mingliang Zhou, Yanhong Ma, Donghan Ma, Jia Qu, Jinyi Zhang, Pengfei Zhang","doi":"10.1364/OL.560030","DOIUrl":"https://doi.org/10.1364/OL.560030","url":null,"abstract":"<p><p>This publisher's note contains a correction to Opt. Lett.50, 1329 (2025)10.1364/OL.546343.</p>","PeriodicalId":19540,"journal":{"name":"Optics letters","volume":"50 6","pages":"1843"},"PeriodicalIF":3.1,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Resolution-enhanced multifocal structured illumination microscopy using fluorescence fluctuations and Fourier ptychography scheme.
IF 3.1 2区 物理与天体物理
Optics letters Pub Date : 2025-03-15 DOI: 10.1364/OL.555763
Bin Yu, Mengjiao Nie, Zizhen Jiang, Danying Lin, Junle Qu, Huiqun Cao
{"title":"Resolution-enhanced multifocal structured illumination microscopy using fluorescence fluctuations and Fourier ptychography scheme.","authors":"Bin Yu, Mengjiao Nie, Zizhen Jiang, Danying Lin, Junle Qu, Huiqun Cao","doi":"10.1364/OL.555763","DOIUrl":"https://doi.org/10.1364/OL.555763","url":null,"abstract":"<p><p>Multifocal structured illumination microscopy (MSIM) provides a twofold resolution enhancement over the optical diffraction limit at depths of up to 50 μm in samples. This is achieved through sparse multifocal excitation patterns and digital image post-processing, making MSIM a highly advantageous technique for the three-dimensional super-resolution (SR) imaging of thick specimens. However, the spatial resolution of MSIM is inherently constrained by its underlying imaging principles. This paper presents what we believe to be a novel method that integrates SR optical fluctuation imaging based on Fourier ptychography and deconvolution (SFPD) with MSIM, termed SFPD-MSIM. Using photoblinking InP/ZnSe/ZnS core-shell quantum dot fluorescent probes for sample labeling, we demonstrate that, compared to wide-field imaging microscopy, SFPD-MSIM achieves fourfold resolution improvement. Additionally, it substantially reduces the image-acquisition time while preserving the structural integrity of the original samples. This advancement marks a major step forward in MSIM technology, providing a powerful tool for detailed structural analysis of complex and thick biological specimens.</p>","PeriodicalId":19540,"journal":{"name":"Optics letters","volume":"50 6","pages":"2005-2008"},"PeriodicalIF":3.1,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Smartphone-based bimodal device (SBBD) for oral precancer diagnosis and biopsy guidance in clinical settings.
IF 3.1 2区 物理与天体物理
Optics letters Pub Date : 2025-03-15 DOI: 10.1364/OL.555254
Nemichand, Shivam Shukla, Bhaswati Singha Deo, Amar Nath Sah, Subrata Mishra, Rachna Rath, Asima Pradhan
{"title":"Smartphone-based bimodal device (SBBD) for oral precancer diagnosis and biopsy guidance in clinical settings.","authors":"Nemichand, Shivam Shukla, Bhaswati Singha Deo, Amar Nath Sah, Subrata Mishra, Rachna Rath, Asima Pradhan","doi":"10.1364/OL.555254","DOIUrl":"https://doi.org/10.1364/OL.555254","url":null,"abstract":"<p><p>We present a smartphone-based bimodal device (SBBD) combining fluorescence imaging and spectroscopy for a noninvasive, portable, cost-effective, and real-time diagnosis of oral precancer. The device employs a 405 nm laser excitation to capture native fluorescence from intrinsic biomarkers, including flavin adenine dinucleotide (FAD) and porphyrin, across 136 subjects representing normal, OPMD, and OSCC. The fluorescence imaging module identifies regions of interest (ROI) based on the red-to-green band ratio (porphyrinFAD), while the spectroscopy module confirms findings through multiple point measurements. A 2D convolutional neural network (CNN) classifies normal tissues, oral potentially malignant disorders (OPMD), and oral squamous cell carcinoma (OSCC) with 97.04% accuracy, 96.13% sensitivity, and 97.73% specificity. Fluorescence spectroscopy, enhanced by an artificial neural network (ANN), achieves 97.44% accuracy, 95.24% sensitivity, and 97.44% specificity. This bimodal approach effectively addresses the diagnostic gap that occurs when either spectroscopy or imaging is used independently for oral cancer detection and biopsy guidance.</p>","PeriodicalId":19540,"journal":{"name":"Optics letters","volume":"50 6","pages":"1993-1996"},"PeriodicalIF":3.1,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Light tunneling and anomalous reflection from the diffraction of complex annuli: modeling the forward light scattering by spherical particles.
IF 3.1 2区 物理与天体物理
Optics letters Pub Date : 2025-03-15 DOI: 10.1364/OL.557822
Lilian Chabrol, Fabrice R A Onofri
{"title":"Light tunneling and anomalous reflection from the diffraction of complex annuli: modeling the forward light scattering by spherical particles.","authors":"Lilian Chabrol, Fabrice R A Onofri","doi":"10.1364/OL.557822","DOIUrl":"https://doi.org/10.1364/OL.557822","url":null,"abstract":"<p><p>Anomalous reflection and tunneling contributions of the high-frequency forward light scattering by non-absorbing spheres are modeled by the scalar diffraction of two complex annuli-one for TM and TE polarizations. Their complex radii, which depend on the refractive indices and particle size, are derived from the complex angular momentum (CAM) method, thus suggesting possible extensions to non-electromagnetic scattering. Coupled with the diffraction of a disk, and a geometrical optics approximation (GOA) for the refractive contributions, we propose an accurate hybrid model that requires one to two orders of magnitude less computational time than the Lorenz-Mie theory (LMT) in the near field, a crucial improvement for, e.g., inverse methods.</p>","PeriodicalId":19540,"journal":{"name":"Optics letters","volume":"50 6","pages":"2061-2064"},"PeriodicalIF":3.1,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Wavelength-tunable and high-heralding-efficiency quantum photon source in a birefringent phase-matched lithium niobate waveguide. 双折射相位匹配铌酸锂波导中的波长可调和高辐射效率量子光子源。
IF 3.1 2区 物理与天体物理
Optics letters Pub Date : 2025-03-15 DOI: 10.1364/OL.547100
Qi-Tao Zhu, Xiao-Xu Fang, He Lu
{"title":"Wavelength-tunable and high-heralding-efficiency quantum photon source in a birefringent phase-matched lithium niobate waveguide.","authors":"Qi-Tao Zhu, Xiao-Xu Fang, He Lu","doi":"10.1364/OL.547100","DOIUrl":"https://doi.org/10.1364/OL.547100","url":null,"abstract":"<p><p>Lithium niobate (LN) is a birefringent material, where the strong birefringence thermo-optic effect is promising for the generation of a quantum photon source with a widely tunable wavelength. Here, we demonstrate birefringent phase matching in a 20-mm-long waveguide fabricated on a 5-<i>μ</i>m-thick <i>x</i>-cut lithium niobate on insulator (LNOI). The waveguide is deviated from the optical axis of LN by an angle of 53.5<sup>∘</sup>, enabling the phase matching between telecom and visible wavelengths. The phase-matching wavelength of this device can be thermally tuned with rate of 0.6 nm/K. We demonstrate the type-1 spontaneous parametric downconversion to generate photon pairs with a brightness of 4.7 MHz/mW and a coincidence-to-accidental ratio of up to 2.8 × 10<sup>5</sup>. Furthermore, the heralded single photon is obtained from the photon pair with an efficiency of 13.8% and a count rate of up to 37.8 kHz.</p>","PeriodicalId":19540,"journal":{"name":"Optics letters","volume":"50 6","pages":"1853-1856"},"PeriodicalIF":3.1,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unidirectional perfect absorber based on a one-dimensional topological photonic crystal heterostructure of Weyl semimetals.
IF 3.1 2区 物理与天体物理
Optics letters Pub Date : 2025-03-15 DOI: 10.1364/OL.557207
Shuai Deng, Huihui Zhong, Chengping Yin, Kunyuan Xu
{"title":"Unidirectional perfect absorber based on a one-dimensional topological photonic crystal heterostructure of Weyl semimetals.","authors":"Shuai Deng, Huihui Zhong, Chengping Yin, Kunyuan Xu","doi":"10.1364/OL.557207","DOIUrl":"https://doi.org/10.1364/OL.557207","url":null,"abstract":"<p><p>We propose a tunable nonreciprocal optical absorber based on a one-dimensional topological photonic crystal heterostructure with Weyl semimetals. The study reveals that embedding a Weyl semimetal thin film at the interface of an asymmetric topological photonic crystal induces coupling between the topological interface states and the epsilon-near-zero effect of the Weyl semimetal. The results show that this coupling leads to hybridized Rabi splitting, and nonreciprocal perfect absorption is observed within the Rabi splitting region, which is closely related to the Fermi energy of the Weyl semimetals. This phenomenon is further elucidated through the analysis of the magnetic field intensity distribution. Additionally, the mode coupling can be tuned by adjusting the rotation angle, the thickness of the Weyl semimetals, and the axial separation vector. These findings hold potential applications in novel absorbers, sensors, and optical switches.</p>","PeriodicalId":19540,"journal":{"name":"Optics letters","volume":"50 6","pages":"1897-1900"},"PeriodicalIF":3.1,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
All-optical diode based on asymmetric nonlinear optical absorption in ternary transition metal chalcogenides. 基于三元过渡金属钙钛矿中非对称非线性光学吸收的全光二极管。
IF 3.1 2区 物理与天体物理
Optics letters Pub Date : 2025-03-15 DOI: 10.1364/OL.553268
Lei Yan, Dechao Shen, Qinyong He, Anping Ge, Guohong Ma, Ye Dai, Liaoxin Sun, Saifeng Zhang
{"title":"All-optical diode based on asymmetric nonlinear optical absorption in ternary transition metal chalcogenides.","authors":"Lei Yan, Dechao Shen, Qinyong He, Anping Ge, Guohong Ma, Ye Dai, Liaoxin Sun, Saifeng Zhang","doi":"10.1364/OL.553268","DOIUrl":"https://doi.org/10.1364/OL.553268","url":null,"abstract":"<p><p>As the typical representative of ternary transition metal chalcogenides, CrPS<sub>4</sub> and MnPS<sub>3</sub> exhibit unique light-matter interactions, demonstrating great potential in photonic devices. In this work, we systematically studied the nonlinear optical (NLO) responses of CrPS<sub>4</sub> and MnPS<sub>3</sub> flakes by the I-scan technique. CrPS<sub>4</sub> and MnPS<sub>3</sub> flakes show saturable absorption and reverse saturation absorption excited by fs laser at wavelengths of 600 nm, respectively. Furthermore, utilizing the non-degenerate transient absorption technology, we observed that the fast and slow carrier relaxation times of CrPS<sub>4</sub> at different probe wavelengths were components with constants of about 1.4-3 ps and 490-1420 ps, respectively. Their excellent ultrafast NLO properties imply that they can be applied in photoelectronic fields for advanced and functional devices. Here, we designed and demonstrated an all-optical diode based on a CrPS<sub>4</sub>/MnPS<sub>3</sub> tandem structure by breaking the time-reversal symmetry, and it achieved nonreciprocal transmission of light similar to that of a p-n electron diode.</p>","PeriodicalId":19540,"journal":{"name":"Optics letters","volume":"50 6","pages":"2109-2112"},"PeriodicalIF":3.1,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Compact underwater single-photon imaging lidar. 紧凑型水下单光子成像激光雷达。
IF 3.1 2区 物理与天体物理
Optics letters Pub Date : 2025-03-15 DOI: 10.1364/OL.557195
Mingjia Shangguan, Ye Li, Yican Mo, Jun Wang, Tao Huang
{"title":"Compact underwater single-photon imaging lidar.","authors":"Mingjia Shangguan, Ye Li, Yican Mo, Jun Wang, Tao Huang","doi":"10.1364/OL.557195","DOIUrl":"https://doi.org/10.1364/OL.557195","url":null,"abstract":"<p><p>Underwater target imaging is important for marine resource exploration, underwater navigation, and related fields. Lidar, with its high angular resolution, excellent depth resolution, and long-distance 3D imaging capabilities, has become an essential tool for target imaging. However, the strong absorption and scattering properties of water, along with the constraints of lidar power consumption and system size, present significant challenges for high-performance lidar systems that are deployable in underwater and even deep-sea environments. To address these challenges, this work proposes and demonstrates a compact, all-fiber underwater imaging lidar. This lidar incorporates highly sensitive single-photon detection technology and features a cylindrical design with a diameter of 0.18 m and a length of 0.68 m. To achieve miniaturization, time-division multiplexing based on fiber arrays is employed, enabling the imaging of small underwater targets using two single-pixel detectors and a two-channel acquisition card. Additionally, an algorithm is introduced to effectively extract and subtract scattering signals from suspended particles in the water column. Tank experiments confirm that the system achieves imaging distances exceeding 10 times the optical attenuation length, and its distance and lateral resolutions are validated using step and stripe targets. With its outstanding performance and broad application potential, this compact lidar system is poised to complement imaging sonar and play a key role in underwater target monitoring and search operations.</p>","PeriodicalId":19540,"journal":{"name":"Optics letters","volume":"50 6","pages":"1957-1960"},"PeriodicalIF":3.1,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Wavelength-tunable blue light generation based on frequency tripling of a random Raman fiber laser.
IF 3.1 2区 物理与天体物理
Optics letters Pub Date : 2025-03-15 DOI: 10.1364/OL.553695
Wei Deng, Lu Chen, Zunwang Bo, Mengqiu Fan, Zhitao Leng, Houkun Liang, Bo Hu, Han Wu
{"title":"Wavelength-tunable blue light generation based on frequency tripling of a random Raman fiber laser.","authors":"Wei Deng, Lu Chen, Zunwang Bo, Mengqiu Fan, Zhitao Leng, Houkun Liang, Bo Hu, Han Wu","doi":"10.1364/OL.553695","DOIUrl":"https://doi.org/10.1364/OL.553695","url":null,"abstract":"<p><p>Nonlinear frequency upconversion of random fiber lasers can generate wavelength flexible visible light with low temporal coherence. In this work, we demonstrate wavelength-tunable blue light generation based on frequency tripling of a random Raman fiber laser (RRFL) in two cascaded periodically poled lithium niobate (PPLN) crystals. The RRFL can deliver watt-level and narrowband lasing in the spectral range of 1412-1435.5 nm, and by using a combination of a second-harmonic generation (SHG) and a sum-frequency generation (SFG) in two cascaded PPLN crystals, blue light with a spectral tuning range from 470.6 to 478.7 nm is experimentally achieved, which is the first demonstration, to the best of our knowledge, of visible light below 500 nm from the frequency conversion of random fiber lasers. Moreover, we confirmed that the temporal intensity fluctuations of the generated blue light are uncorrelated, making such a blue light source suitable for chaotic lidar and temporal ghost imaging applications. We believe the proposed frequency tripling of high-power and tunable RRFL can provide a new platform for generating wavelength flexible and temporal chaotic blue light, which can have promising applications in underwater lidar, display, and sensing applications.</p>","PeriodicalId":19540,"journal":{"name":"Optics letters","volume":"50 6","pages":"2045-2048"},"PeriodicalIF":3.1,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Wideband chaos generation based on an integrated mutual coupling laser.
IF 3.1 2区 物理与天体物理
Optics letters Pub Date : 2025-03-15 DOI: 10.1364/OL.558091
Yuanyuan Guo, Yuanye Zhang, Hua Gao, Longsheng Wang, Pengfa Chang, Hong Han, Zhiwei Jia, Anbang Wang, Yuncai Wang
{"title":"Wideband chaos generation based on an integrated mutual coupling laser.","authors":"Yuanyuan Guo, Yuanye Zhang, Hua Gao, Longsheng Wang, Pengfa Chang, Hong Han, Zhiwei Jia, Anbang Wang, Yuncai Wang","doi":"10.1364/OL.558091","DOIUrl":"https://doi.org/10.1364/OL.558091","url":null,"abstract":"<p><p>To further enhance the bandwidth of an integrated chaotic semiconductor laser, a structure of an integrated mutual coupling laser is proposed. The laser integrates two distributed feedback lasers and two semiconductor optical amplifiers in the middle of the lasers. The dynamic state of the integrated laser undergoes complex changes with the variation of the bias currents of the distributed feedback (DFB) lasers and semiconductor optical amplifiers (SOAs). We find that the bias currents have an influence on the enhancement of chaotic signal bandwidth. The proposed structure can generate over 30 GHz ultra-wide chaotic laser when the DFB and SOA regions are under proper bias current conditions.</p>","PeriodicalId":19540,"journal":{"name":"Optics letters","volume":"50 6","pages":"2009-2012"},"PeriodicalIF":3.1,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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