Nutrition最新文献

{"title":"Navigating nutrition through the decades: Tailoring dietary strategies to women's life stages","authors":"Shilpa Sudhakar Harak M. Pharm., Ph.D. ,&nbsp;Smita Panditrao Shelke M. Pharm. ,&nbsp;Dhanshri Revannath Mali M. Pharm., Ph.D. ,&nbsp;Ayushi Atul Thakkar B. Pharm.","doi":"10.1016/j.nut.2025.112736","DOIUrl":"10.1016/j.nut.2025.112736","url":null,"abstract":"<div><div>The female-specific hormones are responsible for the different metabolic changes occurring in the overall well-being of a woman. Especially highlighted phases are the onset of puberty, menarche, pregnancy, lactation, and menopause. They involve significant metabolic changes, which alter the nutritional requirements. Women, in general, are often unaware of these varied nutritional requirements and fail to inculcate them in their diet, influencing their health. Increased calories, protein, iron, and calcium consumption during adolescence is required for bone growth and the prevention of osteoporosis later in life. The availability through a balanced diet of zinc and essential vitamins such as D, K, and B12 is also critical for a rapidly growing body. At present, infertility is also a pressing issue for couples. Female fertility can be enhanced by a diet high in plant-based protein, dietary fiber, omega-3 fatty acids, vitamins, and minerals. Foods rich in omega-3 fatty acids can help to enhance the quality of eggs, and plant-based proteins reduce the incidence of infertility. Thereafter, during pregnancy, nutritional requirements increase, especially for vitamins B6, B12, and D, calcium, proteins, folate, zinc, and iron. A properly balanced diet can satisfy basic nutritional requirements. However, iron supplements are essential for supporting the blood supply to the placenta and fetus. During menopause and menopausal transition, symptoms are observed like vaginal dryness, hot flashes, and irregular menstruation, followed by an increased threat of cardiovascular diseases, tumors, type 2 diabetes, and osteoporosis. Sufficient intake of protein, calcium, vitamins B, C, and D, and omega-3 fatty acids is important in managing the symptoms. The strategic combination of antioxidant-rich foods with a low-fat, plant-based diet can reduce the risk of cardiovascular disease and regulate body mass. The conclusion of this review is that timely changes in nutrition and strategizing dietary supplements can ease the transition phases of the female lifecycle and improve quality of life.</div></div>","PeriodicalId":19482,"journal":{"name":"Nutrition","volume":"135 ","pages":"Article 112736"},"PeriodicalIF":3.2,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143792491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between adiposity distribution and low-grade systemic inflammation: Tackling multicollinearity","authors":"Vanda Craveiro ,&nbsp;Milton Severo ,&nbsp;Elisabete Ramos","doi":"10.1016/j.nut.2025.112737","DOIUrl":"10.1016/j.nut.2025.112737","url":null,"abstract":"<div><h3>Objectives</h3><div>To examine the association between adiposity distribution and low-grade systemic inflammation, testing how the statistical approach can be used to tackle the multicollinearity between variables of adiposity.</div></div><div><h3>Methods</h3><div>Cross-sectional analysis of 987 adults (27 years old) from the EPITeen cohort (Porto, Portugal). Adiposity distribution was assessed based on the fat distribution of the participants, measured by whole-body dual-energy X-ray absorptiometry (DXA). Low-grade systemic inflammation was determined based on the serum high-sensitivity C-reactive protein (hsCRP) of the participants. The associations were estimated by linear regression models, stratified by sex, and multicollinearity between variables of adiposity was considered.</div></div><div><h3>Results</h3><div>The association (standardized β [95%CI]) between total body fat and hsCRP (ln) was 0.332 (0.252, 0.411) in women and 0.256 (0.175, 0.337) in men. Finally, in women, the association (standardized β [95%CI]) with hsCRP (ln) was −0.014 (−0.094, 0.065) for limb fat and 0.019 (−0.061, 0.099) for trunk fat, and, in men it was −0.136 (−0.216, −0.056) for limb fat and 0.130 (0.050, 0.211) for trunk fat.</div></div><div><h3>Conclusions</h3><div>After a comprehensive study of fat, its overall proinflammatory effect was acknowledged. Trunk fat was more proinflammatory than limb fat, even though the results were only statistically significant in men. Statistical analysis should consider multicollinearity between variables of adiposity, though simpler models could be used to address this problem.</div></div>","PeriodicalId":19482,"journal":{"name":"Nutrition","volume":"135 ","pages":"Article 112737"},"PeriodicalIF":3.2,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143783198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The critical care nutrition landscape in sub-Saharan Africa: Field insights and clinical commentary from resource-limited clinical settings","authors":"Fathima Abdoola MSc ,&nbsp;Harriet Gyamfuah Adu-Amoah MPhil ,&nbsp;Benedicta Kessewah Addo MSc ,&nbsp;Eric Komla Anku MPH ,&nbsp;Lauren Terese Hill PhD ,&nbsp;Bona Mwiinga Hamoonga MSc ,&nbsp;Kondwani Katundu PhD ,&nbsp;Dick Msiska BSc ,&nbsp;African Clinical Nutrition Consortium","doi":"10.1016/j.nut.2025.112740","DOIUrl":"10.1016/j.nut.2025.112740","url":null,"abstract":"<div><div>Critical care resources are very limited on the African continent. Within these limited resources, adequate and formalized critical care nutrition support is an even rarer clinical resource. While nutrition products for nasogastric feeding are specified in international consensus guidelines as essential requirements for critical care, these are desperately undersupplied in African Intensive Care Units (ICU). Malnutrition in ICUs in low and middle income countries is 65–78%, roughly double that of developed countries. Furthermore, malnutrition prevalence among severely ill oncology and infectious disease subgroups is 90–100% in the African setting. Dietetic resources in general are few and even fewer within critical care units. Integration of dietetic skills and services into ICU care is not routine, not governed by formalized protocols and is associated with low insight from non-nutrition health professionals. Overall level of perceived critical care nutrition skill and competency is lacking. These are barriers to ICU nutritional care along with poor compliance with clinical practice guidelines, delays in nutritional referrals, insufficient dietitian-to-patient ratios and severe shortage of medical nutrition products and feeding pumps. Both enteral and parenteral nutrition are subject to improvised formulation options because commercial product acquisition and procurement is not aligned to clinical need and is seldom reimbursed through government health systems. This results in both inadequate and inappropriate nutrition delivery as well as safety concerns. Combined clinical and political strategies for incremental quality enhancements and capacity building for critical care nutrition support are urgently needed in the region.</div></div>","PeriodicalId":19482,"journal":{"name":"Nutrition","volume":"134 ","pages":"Article 112740"},"PeriodicalIF":3.2,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143705841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reduction of food insecurity over time: An unattainable reality for the poorest families?","authors":"Erica Costa Rodrigues Ph.D. ,&nbsp;Raquel de Deus Mendonça Ph.D. ,&nbsp;Priscila Pena Camargo M.D. ,&nbsp;Adriana Lúcia Meireles Ph.D.","doi":"10.1016/j.nut.2025.112738","DOIUrl":"10.1016/j.nut.2025.112738","url":null,"abstract":"<div><h3>Introduction</h3><div>Food insecurity (FI), associated with inadequate access to food, reflects social inequality. Shifts in sociodemographic factors significantly impact household FI. This study initially hypothesized that the progression of the COVID-19 pandemic would exacerbate socioeconomic challenges, thereby influencing the trends and responses related to FI within the studied population.</div></div><div><h3>Objective</h3><div>This study examines how social and demographic factors associated with FI change in an important population group during a health crisis, identifying vulnerable groups.</div></div><div><h3>Methods</h3><div>This longitudinal study analyzed a random sample of students from public schools in two Brazilian municipalities. Data were collected at 9-month intervals at four time points (T0, T1, T2, and T3) between 2020 and 2022. FI was measured using the Brazilian Food Insecurity Scale (BFIS) and analyzed as a discrete numerical variable (BFIS score -0 to 14 points). Comparisons across time points were analyzed using the paired Wilcoxon test. A generalized linear mixed model assessed the relationship between BFIS score and social and demographic variables over time.</div></div><div><h3>Results</h3><div>The average BFIS scores declined from 2.9 at T0 to 2.7 at T1; to 2.2 at T2 and T3, with significant differences between T0 and T2/T3 (<em>P</em> &lt; 0.001), and T1 and T2/T3 (<em>P</em> = 0.017). Higher BFIS scores were associated with families earning less than or equal to half the minimum wage Rate Ratio (RR) =4.93 [95% CI: 3.81–6.36], enrolled in social programs RR =1.14 [95% CI: 1.02–3.81], receiving emergency aid RR =1.15 [95% CI: 1.04–1.28] or food baskets RR=1.30 [95% CI: 1.18–1.43]. Families headed by Black/Brown individuals and women had higher BFIS scores, as did those headed by single individuals and those with low educational attainment.</div></div><div><h3>Conclusion</h3><div>There was no reduction in the average BFIS score for 2020 and 2022 for extremely poor families, despite improvements in other socioeconomic indicators. Families enrolled in social programs, beneficiaries of emergency aid, and households headed by women and black people experienced higher average BFIS scores, highlighting factors in the complex dynamics of FI during COVID-19 and a dynamically oscillating evolution in the sociodemographic landscape.</div></div>","PeriodicalId":19482,"journal":{"name":"Nutrition","volume":"135 ","pages":"Article 112738"},"PeriodicalIF":3.2,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143806849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The roles of vitamin C in infectious diseases: A comprehensive review","authors":"Runze Li ,&nbsp;Liangchao Guan ,&nbsp;Yue Liu ,&nbsp;Zongyi Hu ,&nbsp;Junyu Liu M.Sc. ,&nbsp;Cheng Li Ph.D. ,&nbsp;Hui Min Ph.D.","doi":"10.1016/j.nut.2025.112733","DOIUrl":"10.1016/j.nut.2025.112733","url":null,"abstract":"<div><div>Vitamin C is a versatile nutrient with essential antioxidant properties and roles in amino acid metabolism, collagen promotion, and hormone synthesis. It has long been regarded as benefitting infectious disease management, although its specific roles remain uncertain. The dominant view is that this efficacy not only stems from its redox regulation in the body but also from its profound impact on the immune system. This review provides a comprehensive overview of Vitamin C's effects on redox regulation and shows how the vitamin influences various immune cells and cell-intrinsic innate immunity signaling pathways, thereby updating and expanding our previous perspectives. Clinically, though some studies and case series have suggested potential benefits of Vitamin C in preventing and (or) treating respiratory tract infections and sepsis and septic shock, the evidence remains controversial. The current data is insufficient to support the routine clinical use of Vitamin C in managing these diseases and requires further rigorous evaluation to establish definitive efficacy and safety profiles. This review thoroughly examines current clinical research progress on Vitamin C, summarizes the primary controversies and their underlying causes, and proposes directions for future clinical research. Furthermore, preclinical evidence shows potential roles for Vitamin C in the supplementary treatment of the “Big Three” infectious diseases: acquired immunodeficiency syndrome (AIDS), tuberculosis, and malaria; however, systematic clinical studies in these areas are lacking. We examine related <em>in vitro</em> and animal studies, as well as clinical trials, and discuss potential roles for Vitamin C as a treatment and (or) adjuvant therapy.</div></div>","PeriodicalId":19482,"journal":{"name":"Nutrition","volume":"134 ","pages":"Article 112733"},"PeriodicalIF":3.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143706451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Probiotic Lactiplantibacillus plantarum Lb41 alleviates high-fat diet-induced nonalcoholic fatty liver disease in mice","authors":"Na-Kyoung Lee ,&nbsp;Yunjung Lee ,&nbsp;Da-Soul Shin ,&nbsp;Eunju Park ,&nbsp;Hyun-Dong Paik","doi":"10.1016/j.nut.2025.112735","DOIUrl":"10.1016/j.nut.2025.112735","url":null,"abstract":"<div><h3>Objective</h3><div>Nonalcoholic fatty liver disease (NAFLD) is mainly related to genetics, obesity, insulin resistance, and type 2 diabetes. Probiotic <em>Lactiplantibacillus plantarum</em> Lb41 (Lb41) has not been reported to have hepatoprotective effects. Therefore, the aim of this study is to investigate the preventive effects of Lb41 against NAFLD in high-fat diet (HFD)-fed mice for preventing NAFLD.</div></div><div><h3>Method</h3><div>To induce fatty liver, the mice were given HFD for 5 weeks, followed by silymarin (200 mg/kg) or Lb41 (10⁸ or 10⁹ colony forming units/day) with the HFD for 7 weeks. After 12 weeks, body weight, histological change, serum and hepatic lipid profiles, etc. was performed compared to control and silymarin.</div></div><div><h3>Results</h3><div>Lb41 had significantly reduced body weight (4.87 g) and serum lipids (triglycerides (77.64%), total cholesterol (67.53%), and low-density lipoprotein (40.50%) compared with the HFD group (<em>P</em> &lt; 0.05). Lb41 significantly relieved HFD-associated hepatic injury by reducing aspartate transaminase (0.49–0.57 fold), alanine transaminase (0.49–0.51 fold), and alkaline phosphatase (0.76–0.90 fold) (<em>P</em> &lt; 0.05). Additionally, they had decreased expression levels of peroxisome proliferator-activated receptor (PPAR) γ and sterol regulatory element-binding protein 1c and increased the expression levels of acyl-CoA oxidase, PPARα, carnitine palmitoyltransferase 1, acetyl CoA carboxylase 1, and fatty acid synthase in liver cells. Insulin and leptin levels decreased in the Lb41 treatment group compared with those in the HFD group. Meanwhile, adiponectin levels increased, similar to those in the normal diet group.</div></div><div><h3>Conclusion</h3><div>Based on these findings, Lb41 probiotics have possible hepatoprotective effects and could be used as functional food materials.</div></div>","PeriodicalId":19482,"journal":{"name":"Nutrition","volume":"134 ","pages":"Article 112735"},"PeriodicalIF":3.2,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143705842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of a multicomponent food-as-medicine intervention on behavioral and mental health outcomes for patients with and without food insecurity","authors":"Marcela D. Radtke Ph.D. ,&nbsp;June M. Tester M.D. ,&nbsp;Lan Xiao Ph.D. ,&nbsp;Wei-ting Chen Ph.D. ,&nbsp;Benjamin O. Emmert-Aronson Ph.D. ,&nbsp;Elizabeth A. Markle Ph.D. ,&nbsp;Steven Chen M.D. ,&nbsp;Lisa G. Rosas Ph.D., M.P.H.","doi":"10.1016/j.nut.2025.112734","DOIUrl":"10.1016/j.nut.2025.112734","url":null,"abstract":"<div><h3>Background</h3><div>Increasingly, food-as-medicine (FAM) programs are being implemented as a strategy for improving the health of patients. However, current policies limit nutrition resources to patients with specific chronic condition diagnoses and do not include food insecurity as a qualifying condition.</div></div><div><h3>Objective</h3><div>Explore the impact of Recipe4Health (R4H), a multicomponent FAM intervention, on behavioral and mental health outcomes in patients with and without food insecurity.</div></div><div><h3>Methods</h3><div>Patients (n = 336) with diet-related chronic conditions and/or food insecurity were referred to R4H, which included 16-weekly produce deliveries and behavioral intervention sessions. Food security status was assessed using the U.S. Department of Agriculture 6-item survey. Outcomes included vegetable/fruit intake, physical activity (PA) and mental health. Within- and between-group pre-post changes were assessed using repeated-measures linear mixed-effects models, adjusting for baseline.</div></div><div><h3>Results</h3><div>The majority of patients had one or more chronic conditions (96%) and identified as food insecure (62%). Patients with food insecurity experienced significant increases in daily servings of vegetables/fruit (+0.38 ± 0.15; <em>P</em> = 0.01) and minutes of moderate-to-vigorous PA per week (+28.94 ± 9.84; <em>P</em> &lt; 0.01). Patients with food security did not experience significant increases in vegetables/fruit (<em>P</em> = 0.09) or PA (<em>P</em> = 0.06). Food-insecure and food-secure patients both experienced significant improvements in loneliness, anxiety, and depressive symptoms from baseline (<em>P</em> &lt; 0.01 for all). Between-group differences were observed only for anxiety, where patients with food security experienced significant improvements in anxious symptoms compared to food-insecure patients (–1.24 [–2.33, –0.14]; <em>P</em> = 0.03).</div></div><div><h3>Conclusion</h3><div>Policymakers may consider expanding eligibility criteria to include food insecurity as an independent qualifying condition for FAM.</div></div>","PeriodicalId":19482,"journal":{"name":"Nutrition","volume":"134 ","pages":"Article 112734"},"PeriodicalIF":3.2,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143679271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of node assortativity and internalizing symptoms with ketogenic diet effectiveness in pediatric patients with drug-resistant epilepsy","authors":"Yi-Fen Chen MD ,&nbsp;Wei-Che Lin MD, PhD ,&nbsp;Ting- Yu Su MD ,&nbsp;Tzu-Yun Hsieh MD ,&nbsp;Kai-Yin Hung MSc ,&nbsp;Mei-Hsin Hsu MD ,&nbsp;Ying-Jui Lin MD ,&nbsp;Hsuan-Chang Kuo MD ,&nbsp;Pi-Lien Hung MD, PhD","doi":"10.1016/j.nut.2025.112730","DOIUrl":"10.1016/j.nut.2025.112730","url":null,"abstract":"<div><h3>Background</h3><div>The ketogenic diet (KD) is an effective alternative therapy for drug-resistant epilepsy (DRE). However, there are no established predictors for KD effectiveness. We aimed to investigate the impact of 12 months of KD therapy (KDT) on brain connectivity, as measured by functional magnetic resonance imaging (fMRI), and its correlation with seizure control, behavioral/mood alterations, and parental stress.</div></div><div><h3>Methods</h3><div>Children with DRE were enrolled in this single-center, prospective cohort study from February 2020 to October 2021. They were divided into a control group and a KDT group. The Child Behavior Checklist (CBCL) and Parental Stress Index (PSI) were administered to parents at the initiation of KDT (T0) and at 12 months (T1). Resting-state fMRI was performed at T0 and at 6 months of KDT. The primary outcome was the between-group difference in the change of CBCL/PSI scores, and brain connectivity metrics after KDT, and the secondary outcome involved measuring their correlation with seizure reduction rates.</div></div><div><h3>Results</h3><div>Twenty-two patients with DRE were enrolled. We had 13 patients in the control group and 9 in the KDT group. Our data revealed that 12 months of KDT can reduce monthly seizure frequency. Several subscales of CBCL T-scores were higher at T0 compared with the control group, then becoming comparable at T1. The PSI scores from ’mothers’ reports reduced after receiving KDT. The changes in node assortativity (ΔAssortativity) were positively correlated with behavioral problems and negatively with seizure reduction rates in the KD group.</div></div><div><h3>Conclusions</h3><div>Twelve months of KDT can reduce monthly seizure frequency and improve mood/behavioral disturbances in patients with DRE. Furthermore, KDT could relieve primary caregivers’ stress. A lower ΔAssortativity value was associated with better behavioral outcomes and greater seizure reduction. The ΔAssortativity value in fMRI may be a crucial predictor for the effectiveness of KDT.</div></div>","PeriodicalId":19482,"journal":{"name":"Nutrition","volume":"134 ","pages":"Article 112730"},"PeriodicalIF":3.2,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143679272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and validation of a predictive equation for resting energy expenditure in Japanese patients with interstitial lung disease","authors":"Keisuke Morikawa M.Sc. ,&nbsp;Hiroyuki Takemura ,&nbsp;Kana Kitayama ,&nbsp;Shogo Inaba ,&nbsp;Haruka Imaoka ,&nbsp;Yu Hashitsume ,&nbsp;Yuta Suzuki ,&nbsp;Osamu Hataji M.D. ,&nbsp;Kazuyuki Tabira Ph.D.","doi":"10.1016/j.nut.2025.112729","DOIUrl":"10.1016/j.nut.2025.112729","url":null,"abstract":"<div><h3>Background and Aims</h3><div>This study developed a prediction equation for resting energy expenditure (REE) in patients with interstitial lung disease (ILD) using indirect calorimetry and examined the errors in the prediction equation.</div></div><div><h3>Methods</h3><div>This study consisted of two key phases: Study 1 focused on developing the prediction equation for REE, whereas Study 2 evaluated the accuracy of this equation through validation and error analysis. In Study 1, REE was measured, and a regression model equation was created to predict REE using multiple regression analysis, with measured REE (mREE) as the dependent variable. In Study 2, a Bland-Altman analysis was conducted to examine the phylogenetic error and agreement between predicted REE (pREE) calculated from the prediction equations developed in Study 1 and mREE.</div></div><div><h3>Results</h3><div>In Study 1, mREE was significantly associated with fat-free mass (FFM), and the prediction equation for REE was 456.988 + 22.539 × FFM. The addition error (0.4 ± 166.1, 95% confidence interval (CI): −55.8 to 56.6, <em>P</em> = 0.988) and proportional error (<em>r</em> = 0.223, <em>P</em> = 0.191) between mREE and pREE were not significantly different, with an agreement of 69.4%.</div></div><div><h3>Conclusions</h3><div>The mREE prediction equation developed in this study showed no systematic errors and exhibited higher agreement compared with existing prediction equations. The prediction equation for REE specific to patients with ILD obtained in this study has the potential for clinical application.</div></div>","PeriodicalId":19482,"journal":{"name":"Nutrition","volume":"135 ","pages":"Article 112729"},"PeriodicalIF":3.2,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143783197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating plate waste in Lebanese hospitals: Implications for nutrition and resource management","authors":"Maha Hoteit Ph.D. ,&nbsp;Maroun Khattar M.Sc. ,&nbsp;Jana El Cheikh Mohamad M.Sc. ,&nbsp;Esraa Antar M.Sc. ,&nbsp;Dana Malli M.Sc. ,&nbsp;Nour Badereddine M.Sc. ,&nbsp;Ferial Fattouh M.Sc. ,&nbsp;Sami El Khatib Ph.D. ,&nbsp;Mohamad G. Abiad Ph.D. ,&nbsp;Hussein F. Hassan Ph.D.","doi":"10.1016/j.nut.2025.112715","DOIUrl":"10.1016/j.nut.2025.112715","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aimed to quantify plate waste in Lebanese hospitals and evaluate the nutritional value.</div></div><div><h3>Methods</h3><div>A descriptive cross-sectional study was conducted between April 2023 and September 2023. It involved 155 inpatients from cardiovascular, gastrointestinal, obstetrics-gynecology and surgical wards across 16 hospitals throughout the Lebanese governorates. Plate waste was measured using a calibrated scale by measuring the food sent to the patient (before consumption) and the food left on the plate (after consumption) and computing the percentage of waste by dividing the grams discarded over the grams served, or through visual estimation. Nutritional analysis was performed to assess the magnitude of waste and its nutritional value.</div></div><div><h3>Results</h3><div>The plate waste represented 31.4% of the total amount of food served, equivalent to 366 tons annually in the participating hospitals. The discarded food accounted for 21.4% of the daily estimated energy requirement for patients. Waste was higher in hospitals located in rural areas (<em>P</em>-value = 0.771). The highest waste levels occurred in the obstetrics-gynecology ward and during lunchtime. On average, each patient wasted 404.7 kcal and 21.16 g protein per day. Vegetables were the most wasted food group. The highest mean daily plate waste was for lunch, representing 37.4% of the wasted weight, followed by dinner (35.6%), then breakfast (12.8%).</div></div><div><h3>Conclusion</h3><div>Lebanese hospitals should take pivotal steps to reduce plate waste, lessen its impacts and eventually increase patients’ satisfaction, as well as adopt relevant and efficient strategies to manage the waste generated, as this waste negatively impacts the environment, and puts patients at risk for malnutrition, hidden hunger, and even death.</div></div>","PeriodicalId":19482,"journal":{"name":"Nutrition","volume":"134 ","pages":"Article 112715"},"PeriodicalIF":3.2,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143611210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}