Nutrition最新文献

{"title":"Associations between Patient-Generated Subjective Global Assessment criteria and all-cause mortality among cancer patients: Evidence from baseline and longitudinal analyses","authors":"Yu Min MD ,&nbsp;Tingting Dai MD ,&nbsp;Ge Song MD ,&nbsp;Xuemei Li MD ,&nbsp;Xiaoxia Liu MD ,&nbsp;Zheran Liu MD ,&nbsp;Qian Yang MD ,&nbsp;Rong Jia MD ,&nbsp;Qiwei Yang MD ,&nbsp;Xingchen Peng PhD ,&nbsp;Jitao Zhou PhD","doi":"10.1016/j.nut.2024.112551","DOIUrl":"10.1016/j.nut.2024.112551","url":null,"abstract":"<div><h3>Objectives</h3><p>The prognostic effects of the Patient-Generated Subjective Global Assessment (PG-SGA) criteria in cancer survivors have been observed but require validation in clinical practice. This study was designed to evaluate the prognostic effects of baseline and longitudinal changes in PG-SGA scores on all-cause mortality among Chinese cancer patients in a real-world setting.</p></div><div><h3>Methods</h3><p>Study patients were selected from one representative tertiary hospital in West China. Kaplan-Meier curves and Cox regression analyses were used to estimate the prognostic effect of baseline and dynamic changes in PG-SGA scores on the all-cause mortality of cancer patients. Receiver operating characteristic curves and a concordance index were used to evaluate the predictive accuracy of PG-SGA criteria.</p></div><div><h3>Results</h3><p>A total of 1415 cancer patients were included in this study, with a mean age of 46 years old. Cox regression analysis showed that baseline malnourished status was significantly associated with the survival of cancer patients (PG-SGA 4–8: hazard ratio [HR] = 1.46, 95% confidence interval [CI]: 1.09–1.96, <em>P</em> = 0.012; PG-SGA ≥9: HR = 1.78, 95% CI: 1.34–2.37, <em>P</em> &lt; 0.001). Cancer patients with longitudinal increased PG-SGA scores (&gt;2 points) were observed to have high risks for mortality (HR = 1.69, 95% CI: 1.04–2.74, <em>P</em> = 0.033). Compared with longitudinal changes in PG-SGA scores, baseline malnourished status showed higher predictive power in identifying the risk subgroup (concordance index: 0.646 vs. 0.586). Sensitivity analyses supported the main findings.</p></div><div><h3>Conclusions</h3><p>This study highlights the prognostic value of baseline and dynamic changes in PG-SGA scores for cancer patients, which can help improve their outcomes.</p></div>","PeriodicalId":19482,"journal":{"name":"Nutrition","volume":"127 ","pages":"Article 112551"},"PeriodicalIF":3.2,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142049596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improvement of skin condition and intestinal microbiota via Heyndrickxia coagulans SANK70258 intake: A placebo-controlled, randomized, double-blind, parallel-group comparative study","authors":"Naoyuki Togawa ,&nbsp;Ryouichi Yamada ,&nbsp;Yoshinori Aoki ,&nbsp;Shouhei Suehiro ,&nbsp;Noriyoshi Uchida ,&nbsp;Akane Haseda ,&nbsp;Hiroyo Kagami-Katsuyama ,&nbsp;Naoyuki Honma ,&nbsp;Jun Nishihira","doi":"10.1016/j.nut.2024.112533","DOIUrl":"10.1016/j.nut.2024.112533","url":null,"abstract":"<div><h3>Objective</h3><p><em>Heyndrickxia coagulans</em> SANK70258, a representative probiotic, is known for alleviating inflammation caused by cedar pollen, improving the intestinal environment and bowel movements. A previous study on consuming <em>H. coagulans</em> SANK70258 together with galactooligosaccharides showed a trend toward improvement in skin scaliness scores and subjective assessments of skin roughness. However, the effect of <em>H. coagulans</em> SANK70258 alone on the skin remains unclear. Thus, we aimed to re-evaluate the effects of the intake of <em>H. coagulans</em> SANK70258 alone on skin conditions and the intestinal environment through a clinical trial.</p></div><div><h3>Methods</h3><p>This placebo-controlled, double-blind clinical trial involved 80 Japanese women aged 30 to 65 with perceived skin roughness. Participants were divided into placebo and test groups. Over eight weeks, the test group consumed <em>H. coagulans</em> SANK70258, and its effects on skin condition and intestinal health were examined.</p></div><div><h3>Results</h3><p>The probiotic group showed significant intestinal improvements, with reduced fecal phenol levels (<em>p</em> = 0.044) and pH (<em>p</em> = 0.022), as well as enhanced skin lightness (L* value) (<em>p</em> = 0.040) and liver function tests. Metabolic analyses revealed decreases in fecal Nε-(carboxymethyl)lysine and plasma hydroxyproline, suggesting skin health benefits. There were also significant improvements in skin scaliness (<em>p</em> = 0.015) and bowel movement frequency (<em>p</em> = 0.032) in subgroup analysis.</p></div><div><h3>Conclusions</h3><p><em>H. coagulans</em> SANK70258 can improve skin health by improving the intestinal lining. This probiotic reduces the levels of intestinal putrefactive products and advanced glycation end-product levels in feces, suggesting that it may affect not only skin health but also systemic tissues such as the liver.</p></div>","PeriodicalId":19482,"journal":{"name":"Nutrition","volume":"126 ","pages":"Article 112533"},"PeriodicalIF":3.2,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0899900724001825/pdfft?md5=532a076023ca1cdb6f521344e9ce66ab&pid=1-s2.0-S0899900724001825-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141843149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between body composition phenotypes and treatment toxicity in women with cervical cancer undergoing chemoradiotherapy","authors":"Mariah Azevedo Aredes PhD ,&nbsp;Nathália Silva de Paula MSc ,&nbsp;Gabriela Villaça Chaves PhD","doi":"10.1016/j.nut.2024.112539","DOIUrl":"10.1016/j.nut.2024.112539","url":null,"abstract":"<div><h3>Objective</h3><p>To identify whether there is an association between body composition phenotypes and toxicity to chemoradiotherapy in women with cervical cancer.</p></div><div><h3>Methods</h3><p>This is a prospective cohort study that included 330 adult patients with cervical cancer treated with chemoradiotherapy. Computed tomography images were used to assess skeletal muscle index (SMI) and radiodensity (SMD), total adipose tissue index, and visceral adipose tissue index. Chemoradiotherapy toxicity was assessed weekly, and toxicity-induced modification of treatment (TIMT) was considered as any severe adverse event resulting in treatment interruption, delay, or dose reduction.</p></div><div><h3>Results</h3><p>Approximately 45% of the patients presented at least one unfavorable body composition parameter (lower SMI, lower SMD, higher total adipose tissue index, or higher visceral adipose tissue index), 23% had two conditions, and 3% had three conditions. The incidence of toxicity ≥ grade 3 and TIMT was 55% and 30%, respectively. For adverse events ≥ grade 3, lower SMI was the determining factor for worse outcomes when evaluated alone or combined with lower SMD and normal adiposity. All body composition phenotypes were associated with TIMT, increasing the risk when both conditions were present.</p></div><div><h3>Conclusions</h3><p>Lower SMI was an independent factor for the higher number of adverse events, as it remained a risk factor when analyzed in isolation or in association with adipose tissue. Women with excess adipose tissue associated with lower muscle mass had a risk approximately 4 times higher of delaying or interrupting chemoradiotherapy. Furthermore, for the sum of unfavorable conditions, there was a progressive increase in the risk of TIMT.</p></div>","PeriodicalId":19482,"journal":{"name":"Nutrition","volume":"127 ","pages":"Article 112539"},"PeriodicalIF":3.2,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141784788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Meal kit delivery services in the UK: An evaluation of the nutritional composition of meals","authors":"Nicola Nixon M.Sc.,&nbsp;Hannah Ensaff Ph.D.","doi":"10.1016/j.nut.2024.112538","DOIUrl":"10.1016/j.nut.2024.112538","url":null,"abstract":"<div><h3>Objective</h3><p>To examine meals provided by meal kit delivery services (MKDS) and to evaluate their nutritional composition.</p></div><div><h3>Research Methods and Procedures</h3><p>In this cross-sectional study, the nutritional composition of meals (<em>n</em> 497) from MKDS in the UK, was considered. Energy and nutrient content were compared to dietary guidelines; meals were profiled for fat, saturated fat, total sugars, and salt content.</p></div><div><h3>Results</h3><p>There was a large range in the energy and nutrient content of meals. The levels of saturated fat per serving ranged from 0.4 to 28.0 g (Mdn = 9.0 g), and salt content ranged from 0.2 to 6.4 g (Mdn = 2.2 g). Over half of the meals were profiled as high for fat (51.3%), saturated fat (62.2%) and salt (64.4%). Notably, protein content per portion was high (Mdn = 34.0 g), and dietary fiber content was low (Mdn = 6.4 g). Meals, which had been distinguished by the providers with “health-based” descriptors or tags, had a better nutritional profile for fat, saturated fat, and salt, than other meals; nevertheless, many “health-based” meals profiled high for salt (46.5%) and saturated fat (40.4%).</p></div><div><h3>Conclusions</h3><p>Recipes from MKDS should be revised to improve their nutritional composition; specifically, reductions in salt and saturated fat content and an increase in dietary fiber are needed. Given the variation in the nutritional composition of meals, work is also needed to ascertain the main factors influencing selections made by consumers, and the relevance of guidance and information to support this.</p></div>","PeriodicalId":19482,"journal":{"name":"Nutrition","volume":"128 ","pages":"Article 112538"},"PeriodicalIF":3.2,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0899900724001874/pdfft?md5=d6875e6de37f1bc57d57ac76cff33be1&pid=1-s2.0-S0899900724001874-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141769951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Portable bioimpedance analyzer for remote body composition monitoring: A clinical investigation under controlled conditions","authors":"Elisa Mazza PhD ,&nbsp;Samantha Maurotti PhD ,&nbsp;Yvelise Ferro PhD ,&nbsp;Paola Doria RDs ,&nbsp;Marta Moraca RDs ,&nbsp;Tiziana Montalcini MD, PhD ,&nbsp;Arturo Pujia MD","doi":"10.1016/j.nut.2024.112537","DOIUrl":"10.1016/j.nut.2024.112537","url":null,"abstract":"<div><h3>Objectives</h3><p>In an era when telemedicine is becoming increasingly essential, the development and validation of miniaturized Bioelectrical Impedance Analysis (BIA) devices for accurate and reliable body composition assessment is crucial. This study investigates the BIA Metadieta, a novel miniaturized BIA device, by comparing its performance with that of standard hospital BIA equipment across a diverse demographic. The aim is to enhance remote health monitoring by integrating compact and efficient technology into routine healthcare practices.</p></div><div><h3>Methods</h3><p>A cross-sectional observational study was conducted with 154 participants from the Clinical Nutrition Unit. The study compared resistance (R), reactance (Xc), and phase angle (PhA) measurements obtained from the BIA Metadieta device and a traditional hospital-based BIA device.</p></div><div><h3>Results</h3><p>Analysis revealed strong positive correlations between the BIA Metadieta and the hospital-based device for R (<em>r</em> = 0.988, <em>P</em> &lt; 0.001), Xc (<em>r</em> = 0.946, <em>P</em> &lt; 0.001), and PhA (<em>r</em> = 0.929, <em>P</em> &lt; 0.001), indicating the miniaturized device's high accuracy and reliability. These correlations were consistent across different genders and BMI categories, demonstrating the device's versatility.</p></div><div><h3>Conclusions</h3><p>The BIA Metadieta device, with its miniaturized form factor, represents a significant step forward in the field of remote health monitoring, providing a reliable, accurate, and accessible means for assessing body composition.</p></div>","PeriodicalId":19482,"journal":{"name":"Nutrition","volume":"126 ","pages":"Article 112537"},"PeriodicalIF":3.2,"publicationDate":"2024-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0899900724001862/pdfft?md5=bb1df6bc4ddafb9d83457ea2ade0b945&pid=1-s2.0-S0899900724001862-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141843867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Structured literature review and meta-analysis of food provision trials and vegetable intake","authors":"Danielle J. Polin BA ,&nbsp;Kaci Pickett-Nairne MS ,&nbsp;Adena Nguyen Le ,&nbsp;Deborah H. Glueck PhD ,&nbsp;Carina Venter PhD","doi":"10.1016/j.nut.2024.112535","DOIUrl":"10.1016/j.nut.2024.112535","url":null,"abstract":"","PeriodicalId":19482,"journal":{"name":"Nutrition","volume":"128 ","pages":"Article 112535"},"PeriodicalIF":3.2,"publicationDate":"2024-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141849675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Temporal recovery and prognostic factors for dysphagia following cardiovascular surgery: Retrospective analysis and development of predictive score","authors":"Nao Hashida S.L.P. ,&nbsp;Kiyohito Hosokawa M.D., Ph.D. ,&nbsp;Ai Kawamura M.D., Ph.D. ,&nbsp;Motoyuki Suzuki M.D. ,&nbsp;Itsuki Kitayama M.D. ,&nbsp;Masayuki Nozawa M.D. ,&nbsp;Eri Okajima S.L.P. ,&nbsp;Madoka Sugamoto S.L.P. ,&nbsp;Akinari Sugauchi D.D.S., Ph.D. ,&nbsp;Wataru Sahara M.D., Ph.D. ,&nbsp;Shigeru Miyagawa M.D., Ph.D. ,&nbsp;Hidenori Inohara M.D., Ph.D.","doi":"10.1016/j.nut.2024.112534","DOIUrl":"10.1016/j.nut.2024.112534","url":null,"abstract":"<div><h3>Objective</h3><p>Dysphagia is a common complication associated with cardiovascular surgery (CVS). This study sought to better understand recovery timelines, identify risk factors, and create a prognostic model for oral intake restoration.</p></div><div><h3>Methods</h3><p>This retrospective study included 134 patients who had CVS between April 2022 and March 2024. We assessed swallowing ability through fiberoptic endoscopic evaluation of swallowing (FEES). We randomly divided the patients’ data into a training dataset and a test dataset in a ratio of 70/30 and Kaplan–Meier analyses and Cox regression were used to assess predictors of total oral intake. We also created a scoring system using the estimated regression coefficients.</p></div><div><h3>Results</h3><p>Most patients with CVS achieved total oral intake in 7–11 days after extubation. Over 168 h of intubation, the presence of penetration or aspiration, a poor FEES score (score &gt; 6), and perioperative complications were significant risk factors for delayed total oral intake. The predicting score was calculated by adding the scores for each individual factor, including FEES score, penetration/aspiration, and preoperative complications. Scores ranged 0–8, categorizing patients into 0–2, 3–5, and 6–8 groups, clearly demonstrating that the higher the predicting score, the longer the time to total oral intake in both the training and the test dataset.</p></div><div><h3>Conclusions</h3><p>All risk factors for unsuccessful or delayed total oral intake were intubation for more than a week, poor swallowing ability, and the presence of perioperative complications. The scoring system accurately predicts the restoration of oral intake following CVS.</p></div>","PeriodicalId":19482,"journal":{"name":"Nutrition","volume":"127 ","pages":"Article 112534"},"PeriodicalIF":3.2,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0899900724001837/pdfft?md5=0921176145285ec37fb9639405cc6212&pid=1-s2.0-S0899900724001837-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141852798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic value of sarcopenia and myosteatosis alterations on survival outcomes for esophageal squamous cell carcinoma before and after radiotherapy","authors":"Ningjing Yang M.S. ,&nbsp;Peng Zhou M.S. ,&nbsp;Jiahua Lyu M.D. ,&nbsp;Jing Ren M.S. ,&nbsp;Xinyu Nie M.S. ,&nbsp;Sijia Zhao M.S. ,&nbsp;Yihong Ye M.S.","doi":"10.1016/j.nut.2024.112536","DOIUrl":"10.1016/j.nut.2024.112536","url":null,"abstract":"<div><h3>Objective</h3><p>We assessed the impact and prognostic significance of alterations in muscle quality and quantity (myosteatosis and sarcopenia, respectively) in patients with esophageal cancer treated with radiotherapy (RT).</p></div><div><h3>Methods</h3><p>We retrospectively pooled 258 patients with esophageal squamous cell cancer who underwent RT. Myosteatosis and sarcopenia were determined based on the skeletal muscle index derived from the muscle area and attenuation at the L3 level from computed tomography images. Subgroups were formed as 2 subgroups of non-sarcopenia/myosteatosis and sarcopenia/myosteatosis (with or without other muscle status) at either timepoint of RT, 3 subgroups of only-sarcopenia, only myosteatosis (without other muscle status), and the co-presence of sarcopenia and myosteatosis at either timepoint of RT, as well as 4 subgroups of continuous sarcopenia/myosteatosis, developed sarcopenia/myosteatosis, reduced sarcopenia/myosteatosis and non-sarcopenia/myosteatosis according to alterations of muscle status at both timepoints of RT. Overall survival (OS) was compared. Univariate and multivariate analyses based on Cox regression identified independent risk factors for prognosis.</p></div><div><h3>Results</h3><p>Either pre- or post-RT, patients with sarcopenia and myosteatosis (with or without other muscle status) had poor OS. Patients with only myosteatosis (without other muscle status) showed the best OS (1352 days pre-RT vs. 1648 days post-RT), while patients with concurrent myosteatosis and sarcopenia had the worst OS (907 days pre-RT vs. 706 days post-RT). The ascending order of OS for sarcopenia alterations was as follows: continuous sarcopenia (1093 days), non-sarcopenia (1740 days), developed sarcopenia (2187 days), and reduced sarcopenia (2208 days) (<em>P</em> = 0.002). The ascending order of OS for myosteatosis alterations was ranked as follows: continuous myosteatosis (1165 days), reduced myosteatosis (1275 days), developed myosteatosis (1783 days), and non-myosteatosis (1942 days) (<em>P</em> = 0.061). Univariate and multivariate Cox regression analyses revealed that increased age, longer tumor length, developed myosteatosis, and continuous myosteatosis were independent prognostic factors for OS.</p></div><div><h3>Conclusions</h3><p>Muscle mass status at presentation and alterations in patients with esophageal cancer before and after RT should be considered prognostic indicators.</p></div>","PeriodicalId":19482,"journal":{"name":"Nutrition","volume":"127 ","pages":"Article 112536"},"PeriodicalIF":3.2,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141850608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing clinical and metabolic responses related to hyperlipidemia, MASLD and type 2 diabetes: sleeve versus RYGB","authors":"Sharvika Bharatselvam B.H.Sc. ,&nbsp;Katherine J.P. Schwenger B.A.Sc., R.D., M.A.N., Ph.D. ,&nbsp;Yasaman Ghorbani M.Sc. ,&nbsp;Sandra E. Fischer M.D. ,&nbsp;Timothy D. Jackson M.D. ,&nbsp;Allan Okrainec M.D. ,&nbsp;Johane P. Allard M.D., F.R.C.P.C.","doi":"10.1016/j.nut.2024.112530","DOIUrl":"10.1016/j.nut.2024.112530","url":null,"abstract":"<div><h3>Objective</h3><p>Both Roux-en-Y gastric bypass (RYGB) and laparoscopic sleeve gastrectomy (LSG) are effective at inducing weight loss, but more information is needed on their comparative effectiveness at improving clinical/biochemical outcomes related to the presence of hyperlipidemia, metabolic dysfunction–associated steatotic liver disease (MASLD), or type 2 diabetes (T2D) at baseline. Here we aimed to assess this in real-world practice.</p></div><div><h3>Methods</h3><p>This is a prospective cross-sectional and cohort study of 142 patients who underwent RYGB or LSG as per clinical practice. Clinical/biochemical data were collected at baseline, prior to surgery and 12 months post–bariatric surgery. Liver biopsy was performed during surgery to diagnose MASLD. The main outcome was 12-month changes in lipid parameters, mainly total cholesterol, between types of surgery.</p></div><div><h3>Results: A total of</h3><p>107 participants underwent RYGB and 35 underwent LSG. Both groups were similar at baseline except for a higher proportion of males and waist circumference in the LSG group. At 12 months postsurgery, RYGB versus LSG resulted in a significantly lower body mass index, triglycerides, total cholesterol, and low-density lipoprotein. However, alanine aminotransferase was significantly lower in those who underwent LSG. In subgroup analyses RYGB was superior at improving lipid-related parameters in those with hyperlipidemia, whereas LSG was superior at reducing alanine aminotransferase in those with MASLD.</p></div><div><h3>Conclusions</h3><p>RYGB versus LSG leads to greater reductions in body mass index and lipid parameters, especially in those with hyperlipidemia, whereas LSG showed greater improvements in liver enzymes in those with MASLD.</p></div>","PeriodicalId":19482,"journal":{"name":"Nutrition","volume":"126 ","pages":"Article 112530"},"PeriodicalIF":3.2,"publicationDate":"2024-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141841743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identifying low muscle mass and monitoring body composition changes in newly diagnosed cancer patients: Agreement between multifrequency bioelectrical impedance analysis and computed tomography","authors":"Fang Wang M.D. ,&nbsp;Jianing Xiao B.Sc. ,&nbsp;Qiong Wang M.S. ,&nbsp;Hongnan Zhen Ph.D., M.D. ,&nbsp;Zhikai Liu Ph.D., M.D. ,&nbsp;Kang Yu M.D.","doi":"10.1016/j.nut.2024.112526","DOIUrl":"10.1016/j.nut.2024.112526","url":null,"abstract":"<div><h3>Objectives</h3><div>Low muscle mass (MM) is significant in cancer patients, and computed tomography (CT) is considered the reference standard for MM assessment. We investigated the consistency of CT and multifrequency bioelectrical impedance analysis (mBIA) in detecting body composition at baseline and during anticancer treatment and the relationship between MM and malnutrition as well as complications in lung and cervical cancer patients.</div></div><div><h3>Methods</h3><div>Abdominal CT and mBIA were conducted to assess body composition at baseline for all patients and repeated for patients with cervical cancer after 4 wk of chemoradiotherapy. Concordance was compared by intraclass correlation coefficient and Bland–Altman plots. Receiver operating characteristic analysis was used to assess the diagnostic efficacy of mBIA for low MM. Correlation analysis was conducted to assess the relationship between MM and Nutritional Risk Screening 2002 and Global Leadership Initiative on Malnutrition. Furthermore, we assessed whether there was a difference in the incidence of chemoradiotherapy side effects in the low MM group derived by CT or mBIA.</div></div><div><h3>Results</h3><div>A total of 77 cervical and 73 lung cancer patients were enrolled. mBIA showed fair discriminative capacity (area under the curve = 0.651) for detecting low MM, the concordance of skeletal MM and visceral fat area between CT and mBIA was good (intraclass correlation coefficient = 0.712 and 0.698, respectively), and mBIA and CT had consistent observations of muscle and fat changes (<em>P</em> = 0.051 and 0.124, respectively). There was no difference in the incidence of chemoradiotherapy side effects in the low MM group compared with controls regardless of whether derived by CT or mBIA (<em>P</em> &gt; 0.05). MM was correlated with Nutritional Risk Screening 2002 and Global Leadership Initiative on Malnutrition but showed unsatisfactory prediction of malnutrition (area under the curve &lt;0.7).</div></div><div><h3>Conclusions</h3><div>mBIA- and CT-derived body composition was highly correlated, and agreement was reached on body composition changes during treatment.</div></div>","PeriodicalId":19482,"journal":{"name":"Nutrition","volume":"128 ","pages":"Article 112526"},"PeriodicalIF":3.2,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141690268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}