Nutritional Neuroscience最新文献_第3页

Potential of dietary polyphenols for protection from age-related decline and neurodegeneration: a role for gut microbiota? 膳食多酚保护人体免受衰老和神经退行性病变的潜力：肠道微生物群的作用？

IF 3.6 4区医学

Nutritional Neuroscience Pub Date : 2024-09-01 Epub Date: 2024-01-29 DOI: 10.1080/1028415X.2023.2298098

F C Ross, D E Mayer, J Horn, J F Cryan, D Del Rio, E Randolph, C I R Gill, A Gupta, R P Ross, C Stanton, E A Mayer

{"title":"Potential of dietary polyphenols for protection from age-related decline and neurodegeneration: a role for gut microbiota?","authors":"F C Ross, D E Mayer, J Horn, J F Cryan, D Del Rio, E Randolph, C I R Gill, A Gupta, R P Ross, C Stanton, E A Mayer","doi":"10.1080/1028415X.2023.2298098","DOIUrl":"10.1080/1028415X.2023.2298098","url":null,"abstract":"Many epidemiological studies have shown the beneficial effects of a largely plant-based diet, and the strong association between the consumption of a Mediterranean-type diet with healthy aging including a lower risk of cognitive decline. The Mediterranean diet is characterized by a high intake of olive oil, fruits and vegetables and is rich in dietary fiber and polyphenols - both of which have been postulated to act as important mediators of these benefits. Polyphenols are large molecules produced by plants to protect them from environmental threats and injury. When ingested by humans, as little as 5% of these molecules are absorbed in the small intestine with the majority metabolized by the gut microbiota into absorbable simple phenolic compounds. Flavan-3-ols, a type of flavonoid, contained in grapes, berries, pome fruits, tea, and cocoa have been associated with many beneficial effects on several risk factors for cardiovascular disease, cognitive function and brain regions involved in memory formation. Both preclinical and clinical studies suggest that these brain and heart benefits can be attributed to endothelial vascular effects and anti-inflammatory properties among others. More recently the gut microbiota has emerged as a potential modulator of the aging brain and intriguingly polyphenols have been shown to alter microbiota composition and be metabolized by different microbial species. However, there is a need for well controlled studies in large populations to identify predictors of response, particularly given the vast inter-individual variation of human gut microbiota.","PeriodicalId":19423,"journal":{"name":"Nutritional Neuroscience","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139575873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The impact of flavonoids and BDNF on neurogenic process in various physiological/pathological conditions including ischemic insults: a narrative review. 黄酮类化合物和 BDNF 对包括缺血性损伤在内的各种生理/病理状况下神经源过程的影响：综述。

IF 3.6 4区医学

Nutritional Neuroscience Pub Date : 2024-09-01 Epub Date: 2023-12-27 DOI: 10.1080/1028415X.2023.2296165

Esen Yılmaz, Saltuk Bugra Baltaci, Rasim Mogulkoc, Abdulkerim Kasım Baltaci

{"title":"The impact of flavonoids and BDNF on neurogenic process in various physiological/pathological conditions including ischemic insults: a narrative review.","authors":"Esen Yılmaz, Saltuk Bugra Baltaci, Rasim Mogulkoc, Abdulkerim Kasım Baltaci","doi":"10.1080/1028415X.2023.2296165","DOIUrl":"10.1080/1028415X.2023.2296165","url":null,"abstract":"Objective: Ischemic stroke is the leading cause of mortality and disability worldwide with more than half of survivors living with serious neurological sequelae thus, it has recently attracted considerable attention in the field of medical research. Neurogenesis is the process of formation of new neurons in the brain, including the human brain, from neural stem/progenitor cells [NS/PCs] which reside in neurogenic niches that contain the necessary substances for NS/PC proliferation, differentiation, migration, and maturation into functioning neurons which can integrate into a pre-existing neural network.Neurogenesis can be modulated by many exogenous and endogenous factors, pathological conditions. Both brain-derived neurotrophic factor, and flavonoids can modulate the neurogenic process in physiological conditions and after various pathological conditions including ischemic insults.Aim: This review aims to discuss neurogenesis after ischemic insults and to determine the role of flavonoids and BDNF on neurogenesis under physiological and pathological conditions with a concentration on ischemic insults to the brain in particular.Method: Relevant articles assessing the impact of flavonoids and BDNF on neurogenic processes in various physiological/pathological conditions including ischemic insults within the timeline of 1965 until 2023 were searched using the PubMed database.Conclusions: The selected studies have shown that ischemic insults to the brain induce NS/PC proliferation, differentiation, migration, and maturation into functioning neurons integrating into a pre-existing neural network. Flavonoids and BDNF can modulate neurogenesis in the brain in various physiological/pathological conditions including ischemic insults. In conclusion, flavonoids and BDNF may be involved in post-ischemic brain repair processes through enhancing endogenous neurogenesis.","PeriodicalId":19423,"journal":{"name":"Nutritional Neuroscience","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139049088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Energy-adjusted dietary inflammatory index and cognitive function in Chinese older adults: a population-based cross-sectional study. 中国老年人能量调节饮食炎症指数和认知功能:一项基于人群的横断面研究。

IF 3.6 4区医学

Nutritional Neuroscience Pub Date : 2024-09-01 Epub Date: 2023-11-22 DOI: 10.1080/1028415X.2023.2285537

Lili Chen, Jinxiu Liu, Xiuli Li, Zhaoyi Hou, Yongbao Wei, Mingfeng Chen, Bixia Wang, Huizhen Cao, Rongyan Qiu, Yuping Zhang, Xinli Ji, Ping Zhang, Mianxiang Xue, Linlin Qiu, Linlin Wang, Hong Li

{"title":"Energy-adjusted dietary inflammatory index and cognitive function in Chinese older adults: a population-based cross-sectional study.","authors":"Lili Chen, Jinxiu Liu, Xiuli Li, Zhaoyi Hou, Yongbao Wei, Mingfeng Chen, Bixia Wang, Huizhen Cao, Rongyan Qiu, Yuping Zhang, Xinli Ji, Ping Zhang, Mianxiang Xue, Linlin Qiu, Linlin Wang, Hong Li","doi":"10.1080/1028415X.2023.2285537","DOIUrl":"10.1080/1028415X.2023.2285537","url":null,"abstract":"Diet can regulate systemic inflammation, which may play an important role in the development and progression of cognitive impairment and dementia. To explore the relationship between the dietary inflammatory potential and cognitive ability. A total of 2307 adults aged 60 years or older were recruited from the Fujian Provincial Hospital (Fujian, China). Dietary inflammatory properties were analyzed using the energy-adjusted dietary inflammatory index (E-DII). The Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) were used to assess cognitive function. Logistic regression and restricted cubic spline (RCS) were fit to assess the associations between variables. The MCI subjects with the highest E-DII scores had a higher risk of AD compared to subjects with the lowest E-DII scores (OR = 1.98, 95%CI = 1.49-2.64, P for trend < 0.001). Subjects with the highest E-DII levels were at increased risk of cognitive impairment compared to those with the lowest E-DII levels (OR = 1.56, 95%CI = 1.25-1.93, P for trend < 0.001). The link between E-DII and cognitive impairment was significant in a nonlinear dose response analysis (P for nonlinear = 0.001). Higher E-DII scores were associated with an increased risk of developing AD or cognitive impairment. These findings may contribute to the effective prevention of cognitive impairment by constructing a multidisciplinary synergistic prevention strategy and controlling dietary inflammation levels.","PeriodicalId":19423,"journal":{"name":"Nutritional Neuroscience","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138295652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A systematic review and meta-analysis of chondroitinase ABC promotes functional recovery in rat models of spinal cord injury. 系统回顾和荟萃分析软骨素酶ABC促进大鼠脊髓损伤模型的功能恢复。

IF 3.6 4区医学

Nutritional Neuroscience Pub Date : 2024-09-01 Epub Date: 2023-11-11 DOI: 10.1080/1028415X.2023.2278867

Ya-Yun Zhang, Rui-Rui Xue, Min Yao, Zhuo-Yao Li, Cai-Wei Hu, Yu-Xiang Dai, Yi-de Fang, Xing Ding, Jin-Hai Xu, Xue-Jun Cui, Wen Mo

{"title":"A systematic review and meta-analysis of chondroitinase ABC promotes functional recovery in rat models of spinal cord injury.","authors":"Ya-Yun Zhang, Rui-Rui Xue, Min Yao, Zhuo-Yao Li, Cai-Wei Hu, Yu-Xiang Dai, Yi-de Fang, Xing Ding, Jin-Hai Xu, Xue-Jun Cui, Wen Mo","doi":"10.1080/1028415X.2023.2278867","DOIUrl":"10.1080/1028415X.2023.2278867","url":null,"abstract":"Background: To comprehensively assess the neurologic recovery potential of chondroitinase ABC (ChABC) in rats after spinal cord injury (SCI).Methods: The PubMed, Embase, ScienceDirect, Web of Science, and China National Knowledge Infrastructure databases were searched for animal experiments that evaluated the use of ChABC in the treatment of SCI up to November 2022. Studies reporting neurological function using the Basso, Beattie, and Bresnahan (BBB) scale, as well as assessments of cavity area, lesion area, and glial fibrillary acidic protein (GFAP) levels, were included in the analysis.Results: A total of 46 studies were ultimately selected for inclusion. The results of the study showed that rats with SCI that received ChABC therapy exhibited a significant improvement in locomotor function after 7 days compared with controls (32 studies, weighted mean difference (WMD) = 0.58, [0.33, 0.83], p < 0.00001). Furthermore, the benefits of ChABC therapy were maintained for up to 28 days according to BBB scale. The lesion area was reduced by ChABC (5 studies, WMD = -20.94, [-28.42, -13.46], p < 0.00001). Meanwhile, GFAP levels were reduced in the ChABC treatment group (8 studies, WMD = -29.15, [-41.57, -16.72], p < 0.00001). Cavity area is not statistically significant. The subgroup analysis recommended that a single injection of 10 μL (8 studies, WMD = 2.82, [1.99, 3.65], p < 0.00001) or 20 U/mL (4 studies, WMD = 2.21, [0.73, 3.70], p = 0.003) had a better effect on improving the function. The funnel plot of the BBB scale was found to be essentially symmetrical, indicating a low risk of publication bias.Conclusions: This systematic review and meta-analysis has indicated that ChABC could improve functional recovery in rats after SCI.","PeriodicalId":19423,"journal":{"name":"Nutritional Neuroscience","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89719055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Supplementation with Manihot esculenta Crantz (Cassava) leaves' extract prevents recognition memory deficits and hippocampal antioxidant dysfunction induced by Amyloid-β. 补充木薯叶提取物可防止淀粉样蛋白-β诱导的识别记忆缺陷和海马抗氧化功能障碍。

IF 3.6 4区医学

Nutritional Neuroscience Pub Date : 2024-09-01 Epub Date: 2023-11-10 DOI: 10.1080/1028415X.2023.2280815

Guilherme Salgado Carrazoni, Nathália Billig Garces, Caroline Ramires Cadore, Priscila Marques Sosa, Roberta Cattaneo, Pâmela Billig Mello-Carpes

{"title":"Supplementation with Manihot esculenta Crantz (Cassava) leaves' extract prevents recognition memory deficits and hippocampal antioxidant dysfunction induced by Amyloid-β.","authors":"Guilherme Salgado Carrazoni, Nathália Billig Garces, Caroline Ramires Cadore, Priscila Marques Sosa, Roberta Cattaneo, Pâmela Billig Mello-Carpes","doi":"10.1080/1028415X.2023.2280815","DOIUrl":"10.1080/1028415X.2023.2280815","url":null,"abstract":"Objective: The Manihot esculenta Crantz (Cassava) is a typical South American plant rich in nutrients and energetic compounds. Lately, our group has shown that non-pharmacological interventions with natural antioxidants present different neuroprotective effects on oxidative balance and memory deficits in AD-like animal models. Here, our objective was to evaluate the neuroprotective effects of Cassava leaves' extract (CAS) in an AD-like model induced by amyloid-beta (Aβ) 25-35 peptide.Methods: Male Wistar rats (n = 40; 60 days old) were subjected to 10 days of CAS supplementation; then, we injected 2 μL Aβ 25-35 in the hippocampus by stereotaxic surgery. Ten days later, we evaluated object recognition (OR) memory. Cassavas' total polyphenols, flavonoids, and condensed tannins content were measured, as well as hippocampal lipid peroxidation and total antioxidant capacity.Results: CAS protected against Aβ-induced OR memory deficits. In addition, Aβ promoted antioxidant capacity decrease, while CAS was able to prevent it, in addition to diminishing lipoperoxidation compared to Aβ.Discussion: We show that treatment with Cassava leaves' extract before AD induction prevents recognition memory deficits related to Aβ hippocampal injection. At least part of these effects can be related to the Cassava leaves' extract supplementation effects on diminishing lipid peroxidation and preventing a decrease in the hippocampal total antioxidant capacity in the hippocampus of AD-like animals without adverse effects. Once cassavais a plant of warm and dry ground that can adapt to growon various soil types and seems to resist several insects, our results enable Cassava to be considered asa potential preventive intervention to avoid or minimizeAD-induced memory deficits worldwide.","PeriodicalId":19423,"journal":{"name":"Nutritional Neuroscience","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72210262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between vitamin D, depression, and sleep health in the National Health and Nutrition Examination Surveys: a mediation analysis. 国家健康和营养检查调查中维生素D、抑郁和睡眠健康之间的关系:中介分析

IF 3.6 4区医学

Nutritional Neuroscience Pub Date : 2024-09-01 Epub Date: 2023-11-14 DOI: 10.1080/1028415X.2023.2279363

Jingliang Shuai, Mengqi Gao, Qi Zou, Youming He

{"title":"Association between vitamin D, depression, and sleep health in the National Health and Nutrition Examination Surveys: a mediation analysis.","authors":"Jingliang Shuai, Mengqi Gao, Qi Zou, Youming He","doi":"10.1080/1028415X.2023.2279363","DOIUrl":"10.1080/1028415X.2023.2279363","url":null,"abstract":"Objective: This study aimed to assess the association between vitamin D and sleep health and to investigate whether depression could mediate this relationship.Methods: A cross-sectional analysis was performed using the 2005-2014 US National Health and Nutrition Examination Survey (NHANES) data. The logistic regression models were conducted to evaluate association of serum vitamin D concentrations with sleep health and depression. Mediation analyses were conducted to investigate the mediated effects of depression on the association of vitamin D with sleep health.Results: In multivariate logistic models, vitamin D was found to be negatively associated with an increased risk of poor sleep health, with an odds ratio (OR) of vitamin D deficiency versus sufficiency was 1.256 (95% CI = 1.084-1.455). Additionally, univariate logistic models showed that vitamin D was also negatively associated with depression risk (vitamin D deficiency vs. sufficiency: OR = 1.699, 95% CI = (1.373-2.103). Further mediation analyses showed that the association of vitamin D with sleep health was mediated by depression, with the mediating effects of depression accounted for 44.56% of the total effects.Conclusion: Vitamin D affects sleep health directly and indirectly through depression. The results suggest that interventions increasing intake of vitamin D should be prioritized to promote sleep health of persons with or at risk of depression.","PeriodicalId":19423,"journal":{"name":"Nutritional Neuroscience","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92155681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mediterranean diet-based intervention to improve depressive symptoms: analysis of the PREDIDEP randomized trial. 地中海饮食干预改善抑郁症状:PREDIDEP随机试验分析

IF 3.6 4区医学

Nutritional Neuroscience Pub Date : 2024-09-01 Epub Date: 2023-11-22 DOI: 10.1080/1028415X.2023.2283290

Beatriz M Cabrera-Suárez, Jose L Hernández-Fleta, Patricio Molero, Ana González-Pinto, Francisca Lahortiga, Claudio Cabrera, Carlos Chiclana-Actis, Almudena Sánchez-Villegas

{"title":"Mediterranean diet-based intervention to improve depressive symptoms: analysis of the PREDIDEP randomized trial.","authors":"Beatriz M Cabrera-Suárez, Jose L Hernández-Fleta, Patricio Molero, Ana González-Pinto, Francisca Lahortiga, Claudio Cabrera, Carlos Chiclana-Actis, Almudena Sánchez-Villegas","doi":"10.1080/1028415X.2023.2283290","DOIUrl":"10.1080/1028415X.2023.2283290","url":null,"abstract":"Background: The effect of an intervention based on Mediterranean diet on reducing recurrence risk or subsyndromal depressive symptoms in recovered depressed patients has not been explored.Methods: The PREDIDEP study was a two-year randomized trial designed to assess the effect of the Mediterranean Diet enriched with extra virgin olive oil on depression recurrence. At baseline and at four, eight, 16, 20, and 24 months of follow-up, depressive symptoms were evaluated through the Beck Depression inventory. Cox regression analysis was fitted to assess the role of dietary intervention on the risk of depression recurrence. Mixed effects linear models were used to assess changes in depressive subsyndromal symptoms according to the intervention.Results: After two years of intervention, the dietary intervention group (n = 103) compared to the control group (n = 93) showed no differences regarding depression recurrence risk as main outcome. As secondary outcomes, an improvement of depressive symptoms was yielded at four (-2.15; 95% CI = -4.00 to -0.29) and eight months (-2.42; 95% CI = -4.17 to -0.67) in the intervention group, with no changes in control group. Moreover, at 20 months, significant differences were found between groups (-3.35; 95% CI = -6.08 to -0.61).Conclusions: An intervention with Mediterranean diet in patients with previous depressive episodes might contribute to the reduction of depressive subsyndromal symptoms.","PeriodicalId":19423,"journal":{"name":"Nutritional Neuroscience","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138291541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Does hazelnut consumption affect brain health and function against neurodegenerative diseases? 食用榛子会影响大脑健康和功能，预防神经退行性疾病吗？

IF 3.6 4区医学

Nutritional Neuroscience Pub Date : 2024-09-01 Epub Date: 2023-12-27 DOI: 10.1080/1028415X.2023.2296164

Shadi Talebi, Fariba Khodagholi, Zahra Bahaeddin, Mitra Ansari Dezfouli, Arman Zeinaddini-Meymand, Samuel Berchi Kankam, Forough Foolad, Fatemeh Alijaniha, Fatemeh Fayazi Piranghar

{"title":"Does hazelnut consumption affect brain health and function against neurodegenerative diseases?","authors":"Shadi Talebi, Fariba Khodagholi, Zahra Bahaeddin, Mitra Ansari Dezfouli, Arman Zeinaddini-Meymand, Samuel Berchi Kankam, Forough Foolad, Fatemeh Alijaniha, Fatemeh Fayazi Piranghar","doi":"10.1080/1028415X.2023.2296164","DOIUrl":"10.1080/1028415X.2023.2296164","url":null,"abstract":"Introduction: A healthy daily diet and consuming certain nutrients, such as polyphenols, vitamins, and unsaturated fatty acids, may help neuronal health maintenance. Polyphenolic chemicals, which have antioxidant and anti-inflammatory properties, are involved in the neuroprotective pathway. Because of their nutritional value, nuts have been shown in recent research to be helpful in neuroprotection.Objective: Hazelnut is often consumed worldwide in various items, including processed foods, particularly in bakery, chocolate, and confectionery products. This nut is an excellent source of vitamins, amino acids, tocopherols, phytosterols, polyphenols, minerals, and unsaturated fatty acids. Consuming hazelnut may attenuate the risk of neurodegenerative disorders including Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, multiple sclerosis, and Huntington's disease due to its anti-inflammatory and anti-oxidant qualities.Results: Many documents introduce hazelnut as an excellent choice to provide neuroprotection against neurodegenerative disorders and there is some direct proof of its neuroprotective effects.Discussion: So hazelnut consumption in daily diet may reduce neurodegenerative disease risk and be advantageous in reducing the imposed costs of dealing with neurodegenerative diseases.","PeriodicalId":19423,"journal":{"name":"Nutritional Neuroscience","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139049087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between dietary fat intake and history of stroke in US adults: findings from National Health and Nutrition Examination Survey 2007-2018. 美国成年人膳食脂肪摄入量与中风病史之间的关系：2007-2018 年全国健康与营养调查的结果。

IF 3.6 4区医学

Nutritional Neuroscience Pub Date : 2024-08-22 DOI: 10.1080/1028415X.2024.2391652

Juanying Zhen, Bernard Man Yung Cheung, Chao Li

{"title":"Association between dietary fat intake and history of stroke in US adults: findings from National Health and Nutrition Examination Survey 2007-2018.","authors":"Juanying Zhen, Bernard Man Yung Cheung, Chao Li","doi":"10.1080/1028415X.2024.2391652","DOIUrl":"https://doi.org/10.1080/1028415X.2024.2391652","url":null,"abstract":"Objectives: Diet is an important target for primary prevention of stroke. There are mixed findings on the relationship between dietary fat intake and stroke. We aimed to investigate the relationship of stroke with fats, including total fat, saturated fatty acids (SFA), monounsaturated fatty acids (MUFA) and polyunsaturated fatty acids (PUFA).Methods: We analysed data on 27,673 participants who had valid data on dietary fat intake and history of stroke from the National Health and Nutrition Examination Survey 2007-2018. History of stroke was defined according to previous diagnosis by doctors or other health professional. Data on 24-h dietary recalls was collected using Automated Multiple-Pass Method. Age, sex, race/ethnicity, total calories, body mass index, diabetes, hypertension, hypercholesterolaemia, smoking, alcohol consumption and physical activity were adjusted in multivariable models.Results: 3.8% (n = 1,054) of participants had a diagnosis of stroke. History of stroke was inversely associated with total fat (OR = 0.89, 95% CI = 0.79-0.99, P = 0.037), SFA (OR = 0.46, 95% CI = 0.23-0.91) and MUFA (OR = 0.08, 95% CI = 0.02-0.38, P = 0.002) from supplements. There was an inverse association between history of stroke and PUFA intake (from diet: quartile 4 vs quartile 1, OR = 0.58, 95% CI = 0.43-0.78, P for trend = 0.003; from supplements: OR = 0.44, 95% CI = 0.27-0.72, P = 0.001).Conclusions: In this large-scale nationally representative study, stroke is inversely associated with fat intake from supplements and PUFA intake from diet. While lifestyle choices may not be the most vital health factor for stroke patients, increasing fat intake from specific supplements does provide additional motivation for undertaking the difficult challenge of stroke prevention.","PeriodicalId":19423,"journal":{"name":"Nutritional Neuroscience","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142036506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of probiotics as an adjunctive therapy with Ritalin among ADHD children and adolescents: a triple-blind randomized controlled trial. 益生菌作为利他林的辅助疗法对多动症儿童和青少年的影响：三重盲法随机对照试验。

IF 3.6 4区医学

Nutritional Neuroscience Pub Date : 2024-08-20 DOI: 10.1080/1028415X.2024.2391655

Zahra Sadat Sangsefidi, Zohreh Sadat Sangsefidi, Fatemeh Moharreri, Aazam Sadat Heydari Yazdi, Saeid Eslami, Bahareh Emadzadeh, Behrouz Ghorani, Mahboobe Sarabi-Jamab, Atefeh Farahmand, Atena Modiri Dovom, Ali Ghanaei, Maryam Emadzadeh

{"title":"Effect of probiotics as an adjunctive therapy with Ritalin among ADHD children and adolescents: a triple-blind randomized controlled trial.","authors":"Zahra Sadat Sangsefidi, Zohreh Sadat Sangsefidi, Fatemeh Moharreri, Aazam Sadat Heydari Yazdi, Saeid Eslami, Bahareh Emadzadeh, Behrouz Ghorani, Mahboobe Sarabi-Jamab, Atefeh Farahmand, Atena Modiri Dovom, Ali Ghanaei, Maryam Emadzadeh","doi":"10.1080/1028415X.2024.2391655","DOIUrl":"https://doi.org/10.1080/1028415X.2024.2391655","url":null,"abstract":"Objective: Attention Deficit Hyperactivity Disorder (ADHD) is one of the most common mental disorders in children. Evidence regarding the impact of probiotics supplementation in ADHD children is limited and controversial. Thus, this study aimed to assess the effect of probiotics as an adjunctive therapy with Ritalin among ADHD children and adolescents.Methods: This study was a triple-blind, randomized controlled trial of 60 Iranian ADHD patients aged four to sixteen. The participants were randomly assigned to receive probiotics supplements containing both Lactobacillus plantarum PTCC 1896™ (A7) and Bifidobacterium animalis subsp. Lactis (BB-12®) (n = 30) or placebo (n = 30) for 8 weeks. ADHD symptoms were assessed using Conners' Parent Rating Scale (CPRS) and Integrated Visual and Auditory Continuous Performance Test (IVA/CPT) at baseline and during the study.Results: This study showed a significant decrease in the CPRS total score after 4 weeks of intervention in the probiotic group (baseline: 43.96 ± 21.52; fourth week: 37.22 ± 23.01; p = 0.01). However, no significant finding was found for the total score of the CPRS after 8 weeks. Moreover, at the end of the study, a significant increase was observed in score of auditory response control in the probiotic versus the placebo group (probiotic: 91.55 ± 16.69; placebo: 80.55 ± 17.43; p = 0.02).Conclusions: Probiotics supplementation with Ritalin may have some beneficial effects among ADHD children and adolescents, such as improving auditory response control and total score of CPRS. However, further clinical trials are required to clarify the impact of probiotics on ADHD.","PeriodicalId":19423,"journal":{"name":"Nutritional Neuroscience","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142009086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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