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On the Barriers and Enablers to Bariatric Surgery: A Qualitative Study with Bariatric Surgeons. 减肥手术的障碍和促进因素:对减肥外科医生的定性研究。
IF 4.7 3区 医学
Obesity Facts Pub Date : 2025-06-28 DOI: 10.1159/000547169
Mia Majstorovic, Anna Chur-Hansen, Jane Andrews, Anne L J Burke
{"title":"On the Barriers and Enablers to Bariatric Surgery: A Qualitative Study with Bariatric Surgeons.","authors":"Mia Majstorovic, Anna Chur-Hansen, Jane Andrews, Anne L J Burke","doi":"10.1159/000547169","DOIUrl":"10.1159/000547169","url":null,"abstract":"<p><strong>Introduction: </strong>Bariatric surgery effectively treats severe obesity; however, publicly funded bariatric surgery in Australia and New Zealand is limited. Bariatric surgeons play an important role in deciding individuals' suitability for surgery. This study explored Australian and New Zealand bariatric surgeons' views on barriers and enablers to bariatric surgery.</p><p><strong>Methods: </strong>Sixteen bariatric surgeons and registrars across Australia and New Zealand were interviewed in 2023 about their opinions on barriers and enablers to bariatric surgery. Conventional qualitative content analysis was used to synthesise the data.</p><p><strong>Results: </strong>Eight content categories originated from the analysis: (1) patient characteristics; (2) factors related to a patient's residential location; (3) economic factors; (4) lifestyle factors; (5) health-related factors; (6) surgery-related fears and concerns; (7) social factors; and (8) institutional and organisational factors. Surgical demand and supply issues were salient in discussions about the pre-operative process and patient (non)progression to surgery. Patients' financial circumstances were similarly emphasised. Societal values and norms, including gender stereotypes, were featured, and the role of close others was substantiated, with patients' families and friends considered both barriers and enablers to surgery.</p><p><strong>Conclusion: </strong>Participants discussed more barriers than enablers to bariatric surgery. Their views generally aligned with the patient-based literature; however, the qualitative nature of the study allowed for the perceived reasons underlying the barriers and enablers to be explored. Findings offer potential avenues for modifying the pre-operative process to better support patients' needs and promote equity in access to surgery.</p>","PeriodicalId":19414,"journal":{"name":"Obesity Facts","volume":" ","pages":"1-11"},"PeriodicalIF":4.7,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12324784/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144529096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diverse Obesity Trajectories in a Family Including Identical Twins with a Pathogenic MC4R Variant. 具有致病性MC4R变异的同卵双胞胎的不同肥胖轨迹
IF 3.9 3区 医学
Obesity Facts Pub Date : 2025-06-25 DOI: 10.1159/000546795
Jane Jia Xin Lim, Amanda J Hooper, Joan Khoo, Wann Jia Loh
{"title":"Diverse Obesity Trajectories in a Family Including Identical Twins with a Pathogenic MC4R Variant.","authors":"Jane Jia Xin Lim, Amanda J Hooper, Joan Khoo, Wann Jia Loh","doi":"10.1159/000546795","DOIUrl":"10.1159/000546795","url":null,"abstract":"<p><strong>Introduction: </strong>Pathogenic heterozygous melanocortin-4 receptor (MC4R) variants are the most common cause of monogenic obesity, affecting central satiety and appetite regulatory areas of the brain.</p><p><strong>Case presentations: </strong>We report a pedigree with a pathogenic MC4R variant (c.380C>T, p.Ser127Leu). In the proband with obesity (BMI 35 kg/m2) and severe insulin resistance, use of combination of semaglutide and naltrexone-bupropion was successful in reducing insulin requirements and weight. His adult monozygotic twin daughters both had childhood-onset obesity; however, weight trajectories differed. Twin 1 had a peak BMI of 29.1 kg/m2, which decreased to 19.7 kg/m2 with intensive exercise and diet control without weight-lowering medication. Twin 2 had a sedentary lifestyle and epilepsy and had a peak BMI of 30.1 kg/m2; she responded well to naltrexone-bupropion and BMI decreased to 26 kg/m2.</p><p><strong>Conclusion: </strong>The manifestation of obesity, even in cases of monogenic obesity, can vary significantly due to the influence of environmental and lifestyle factors.</p>","PeriodicalId":19414,"journal":{"name":"Obesity Facts","volume":" ","pages":"1-10"},"PeriodicalIF":3.9,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12270488/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144497563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preferences for Body Weight-Related Terminology for People Living with Obesity: Results from the ACTION-DK Study. 肥胖人群对体重相关术语的偏好:来自ACTION-DK研究的结果
IF 4.7 3区 医学
Obesity Facts Pub Date : 2025-06-21 DOI: 10.1159/000546218
Anette Schnieber, Pernille Andreassen, Tina Vilsbøll, Per Nielsen, Cecilie Yssing, Amanda Falah Rasmussen, Signe Stensen, Kasper Nørremark, Jens Meldgaard Bruun
{"title":"Preferences for Body Weight-Related Terminology for People Living with Obesity: Results from the ACTION-DK Study.","authors":"Anette Schnieber, Pernille Andreassen, Tina Vilsbøll, Per Nielsen, Cecilie Yssing, Amanda Falah Rasmussen, Signe Stensen, Kasper Nørremark, Jens Meldgaard Bruun","doi":"10.1159/000546218","DOIUrl":"10.1159/000546218","url":null,"abstract":"<p><strong>Introduction: </strong>When discussing body weight with health care professionals (HCPs), people living with obesity (PwO) can feel stigmatised by specific terms. In English-speaking research settings, PwO have expressed preferences for \"technical\" or health-related terms (e.g., weight; body mass index [BMI]), as opposed to vernacular terms (e.g., fatness), but no such studies have been conducted in a Danish linguistic and cultural setting. The aim of the present study was to investigate preferences of PwO for weight-related terminology in conversations with HCPs in a Danish context.</p><p><strong>Methods: </strong>The study utilised survey data from the Awareness, Care, and Treatment In Obesity maNagement-Denmark (ACTION-DK) study among Danish adults with a self-reported BMI ≥30.0 kg/m2.</p><p><strong>Results: </strong>A total of 879 Danish adults with obesity completed the questionnaire on preferred weight-related terminology, preferred HCP communication actions in weight loss conversation, and acceptability of HCPs raising the topic of weight. Respondents preferred technical or health related, person-first terminology; weight, overweight, high BMI, and higher weight were most preferred; fat, extra large, chubby, morbid obesity, and curvy were least preferred. A total of 71% respondents appreciated their HCP raising the topic of weight. When prioritising HCP communication actions in weight-loss conversations, PwO emphasised empathy and respectfulness over concrete actions.</p><p><strong>Conclusion: </strong>The present study is the first to investigate PwO preference for weight-related terminology in a Danish setting, with findings overall in support of similar international studies. The identification of specific, acceptable terms, together with the proportion of respondents appreciating their HCP raising the topic of weight, indicate that respectful conversations between PwO and HCPs about weight are possible. However, HCPs should always enquire about an individual's preferences.</p>","PeriodicalId":19414,"journal":{"name":"Obesity Facts","volume":" ","pages":"1-15"},"PeriodicalIF":4.7,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12331247/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144369031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Differential Cardiac Remodeling in Overweight and Obesity: Insights from Noninvasive Imaging. 超重和肥胖的不同心脏重构:来自无创成像的见解。
IF 4.7 3区 医学
Obesity Facts Pub Date : 2025-06-21 DOI: 10.1159/000546406
Wenjun Liu, Shanshan Li, Yue Yu, Lele Cheng, Zixuan Meng, Yaxuan Xue, Renjie Liu, Hui Liu, Jian Yang, Yue Wu, Zhijie Jian
{"title":"Differential Cardiac Remodeling in Overweight and Obesity: Insights from Noninvasive Imaging.","authors":"Wenjun Liu, Shanshan Li, Yue Yu, Lele Cheng, Zixuan Meng, Yaxuan Xue, Renjie Liu, Hui Liu, Jian Yang, Yue Wu, Zhijie Jian","doi":"10.1159/000546406","DOIUrl":"10.1159/000546406","url":null,"abstract":"<p><strong>Introduction: </strong>Weight gain is associated with cardiac abnormalities, but the differences in cardiac remodeling between overweight and obesity (O&amp;O) remain unclear. This study explored the structural and functional cardiac changes associated with O&amp;O using noninvasive imaging.</p><p><strong>Methods: </strong>A retrospective study included participants from August 2021 to July 2023. Clinical data, laboratory results, and echocardiography reports were collected, and cardiac magnetic resonance imaging was post-processed. Cardiac structural and functional parameters were compared among healthy weight, overweight, and obesity groups, and their relationships with body mass index (BMI) were analyzed.</p><p><strong>Results: </strong>A total of 275 participants were included. Significant differences in left ventricular end-diastolic/systolic diameters, left atrial diameter, left ventricular ejection fraction, and stroke volume index were observed between O&amp;O and healthy weight groups (p < 0.05). However, no significant differences were found between the O&amp;O groups in terms of left ventricular septum thickness, left ventricular posterior wall thickness, cardiac index, or end-systolic volume index (p > 0.05). Multivariable regression showed a positive correlation between BMI and cardiac structural/functional indicators (p < 0.05), with greater changes in obesity. Loess spline analysis revealed that cardiac remodeling was more pronounced during the overweight stage.</p><p><strong>Conclusions: </strong>Both O&amp;O are associated with larger cardiac dimensions, increased myocardial mass, and impaired function. Cardiac remodeling accelerates during the overweight stage, emphasizing the need for early detection and intervention in overweight individuals to mitigate future health risks.</p>","PeriodicalId":19414,"journal":{"name":"Obesity Facts","volume":" ","pages":"1-15"},"PeriodicalIF":4.7,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12252759/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144369115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
EASO Position Statement: Women with Obesity across the Reproductive Life - Fertility, Preconception, Pregnancy, Postpartum, and Breastfeeding. EASO立场声明:妇女与肥胖在整个生殖生命-生育,孕前,怀孕,产后,和母乳喂养。
IF 4.7 3区 医学
Obesity Facts Pub Date : 2025-06-21 DOI: 10.1159/000546449
Francesca Filippi-Arriaga, Nidhi Agarwal, Diana Rodrigues-Martins, Mariana P Monteiro, Emilia Huvinen, Sara G I Suliman, Barbara McGowan, Andreea Ciudin
{"title":"EASO Position Statement: Women with Obesity across the Reproductive Life - Fertility, Preconception, Pregnancy, Postpartum, and Breastfeeding.","authors":"Francesca Filippi-Arriaga, Nidhi Agarwal, Diana Rodrigues-Martins, Mariana P Monteiro, Emilia Huvinen, Sara G I Suliman, Barbara McGowan, Andreea Ciudin","doi":"10.1159/000546449","DOIUrl":"10.1159/000546449","url":null,"abstract":"<p><strong>Background: </strong>Obesity management in women presents distinct challenges across their lifespan. However, there is limited evidence or recommendations focused solely on women living with obesity.</p><p><strong>Summary: </strong>This European Association for the Study of Obesity (EASO) position statement is based on an expert comprehensive review and summary of the available scientific evidence on women living with obesity. It aims to guide the health and medical assessment of these women during their reproductive life (fertility, preconception, pregnancy, postpartum, and breastfeeding).</p><p><strong>Key messages: </strong>1. To better diagnose obesity in women beyond BMI, the use of at least one additional anthropometric measure, like waist-to-height ratio (WHtR), is strongly recommended. When available, the use of bioelectrical impedance vector analysis is encouraged. 2. Women with obesity should be offered obesity management counseling and psychological support. 3. Obesity can negatively impact fertility; weight loss of 5-10% over 6 months improves fertility. 4. In women with Polycystic Ovary Syndrome (PCOS), treatment with metformin and GLP-1 receptor agonists or surgery can be considered. 5. Current recommendations for pregestational obesity suggest a gestational weight gain (GWG) of 5-9 kg. Lower GWG targets should be considered, particularly for class II or III obesity. 6. There is limited clinical data on the safety and efficacy of obesity medication during pregnancy or lactation. 7. All pregnant women with obesity should be offered prenatal screening for fetal anomalies, with discussion of the potential limitations of diagnostic tests and additional growth ultrasounds offered on an individual basis. 8. All pregnant women with a BMI ≥30 kg/m2 should be screened for gestational diabetes in early pregnancy. Measures to prevent preeclampsia should be taken and the need for thromboprophylaxis assessed. 9. Intrapartum fetal surveillance is recommended during active labor. 10. Postpartum weight management is needed to mitigate the risk of adverse outcomes for the mother and for subsequent pregnancies. The assessment of appropriate contraceptive methods during the postpartum and breastfeeding period is crucial.</p>","PeriodicalId":19414,"journal":{"name":"Obesity Facts","volume":" ","pages":"1-15"},"PeriodicalIF":4.7,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12306975/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144369030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Body Composition and Function in Patients with Obesity in Clinical Practice: Beyond the Body Mass Index. 肥胖患者的身体组成和功能在临床中的应用。除了BMI。
IF 4.7 3区 医学
Obesity Facts Pub Date : 2025-06-12 DOI: 10.1159/000546820
María García Olivares, Lara Dalla Rovere, Rocío Fernández Jiménez, Carmen Hardy Añón, Cristina Herola Cobos, José Abuín Fernández, Virginia Morillas Jimeneza, Francisco Hevilla Sánchez, José Manuel García-Almeida
{"title":"Body Composition and Function in Patients with Obesity in Clinical Practice: Beyond the Body Mass Index.","authors":"María García Olivares, Lara Dalla Rovere, Rocío Fernández Jiménez, Carmen Hardy Añón, Cristina Herola Cobos, José Abuín Fernández, Virginia Morillas Jimeneza, Francisco Hevilla Sánchez, José Manuel García-Almeida","doi":"10.1159/000546820","DOIUrl":"10.1159/000546820","url":null,"abstract":"<p><strong>Introduction: </strong>Assessing the nutritional and morphofunctional status of patients with obesity (PwO) is essential for optimizing their management. Nutritional ultrasound (NU) is a noninvasive, portable technique that offers insights into muscle and adipose tissue status. Combining NU with bioelectrical impedance analysis (BIA) and handgrip strength (HGS) may improve the assessment of body composition and muscle functionality. This study aimed to evaluate the usefulness of NU as a primary tool for morphofunctional assessment in PwO while comparing and complementing it with BIA and HGS.</p><p><strong>Methods: </strong>A cross-sectional observational study was conducted including 178 PwO. Body composition was assessed using NU, single-frequency BIA, and HGS dynamometry. Correlations and multiple linear regression models were used to evaluate associations between NU, BIA, and HGS parameters.</p><p><strong>Results: </strong>Significant correlations were found between NU-measured quadriceps rectus femoris-cross-sectional area (RF-CSA) and BIA-derived fat-free mass markers, such as body cell mass (BCM) (r = 0.638, p < 0.001) and appendicular skeletal muscle mass (r = 0.591, p < 0.001). Additionally, leg subcutaneous adipose tissue measured by NU was highly correlated with BIA-calculated fat mass (r = 0.656, p < 0.001). Linear regression analyses further confirmed the importance of RF-CSA as a strong predictor of BCM, along with HGS and body mass index, explaining 78.2% of the variability in BCM (R2 = 0.782, Akaike Information Criterion = 672).</p><p><strong>Conclusion: </strong>These findings suggest that NU, combined with BIA and HGS, provides a comprehensive, practical tool for assessing body composition and muscle function in obesity management, with the potential for routine application in clinical settings.</p>","PeriodicalId":19414,"journal":{"name":"Obesity Facts","volume":" ","pages":"1-10"},"PeriodicalIF":4.7,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12503527/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144285747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Laparoscopic Sleeve Gastrectomy under Regional Anesthesia: First Case Reported in Italy. 区域麻醉下腹腔镜袖式胃切除术。意大利报告首例病例]。
IF 3.9 3区 医学
Obesity Facts Pub Date : 2025-05-23 DOI: 10.1159/000540800
Chiara Mazzone, Maria Sofia, Giorgia Litrico, Enrico Vaccarisi, Luisa Gallo, Gaetano La Greca, Saverio Latteri
{"title":"Laparoscopic Sleeve Gastrectomy under Regional Anesthesia: First Case Reported in Italy.","authors":"Chiara Mazzone, Maria Sofia, Giorgia Litrico, Enrico Vaccarisi, Luisa Gallo, Gaetano La Greca, Saverio Latteri","doi":"10.1159/000540800","DOIUrl":"10.1159/000540800","url":null,"abstract":"<p><strong>Introduction: </strong>This case report presents the first documented instance in Italy of successful sleeve gastrectomy performed under spinal anesthesia, marking a significant milestone in the field of bariatric surgery.</p><p><strong>Case presentation: </strong>Highlighting the innovative approach to anesthesia in the context of obesity treatment, this study explains the procedure and postoperative outcomes of a 46-year-old female patient with a BMI of 38 kg/m2, who had a history of moderate Obstructive Sleep Apnea Syndrome. Despite the complications associated with obese patients undergoing bariatric surgery, the use of regional anesthesia (RA) facilitated a favorable outcome, minimizing perioperative risks and enhancing postoperative recovery. The patient experienced no pain or respiratory complications, demonstrating the safety and feasibility of RA for sleeve gastrectomy, and underscoring its potential as a viable alternative to general anesthesia in bariatric surgery. In addition, the use of the Ramsey scale (score: 2) provided valuable insights into the patient's sedation level, contributing to the overall assessment of the anesthetic approach.</p><p><strong>Conclusion: </strong>This case contributes to the growing evidence supporting the use of RA in laparoscopic surgeries, offering significant advantages in terms of patient safety, satisfaction, and recovery outcomes.</p>","PeriodicalId":19414,"journal":{"name":"Obesity Facts","volume":" ","pages":"1-6"},"PeriodicalIF":3.9,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12215440/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevention of Obesity among Adults: Evidence- and Consensus-Based Guideline. 预防成人肥胖:基于证据和共识的指南。
IF 3.9 3区 医学
Obesity Facts Pub Date : 2025-05-22 DOI: 10.1159/000546415
Peter von Philipsborn, Melanie Bahlke, Christina Breidenassel, Christina Holzapfel, Christine Joisten, Sandra Plachta-Danielzik, Monika Nothacker, Diana Rubin, Marion Rung-Friebe, Martina de Zwaan, Hans Hauner
{"title":"Prevention of Obesity among Adults: Evidence- and Consensus-Based Guideline.","authors":"Peter von Philipsborn, Melanie Bahlke, Christina Breidenassel, Christina Holzapfel, Christine Joisten, Sandra Plachta-Danielzik, Monika Nothacker, Diana Rubin, Marion Rung-Friebe, Martina de Zwaan, Hans Hauner","doi":"10.1159/000546415","DOIUrl":"10.1159/000546415","url":null,"abstract":"<p><strong>Background: </strong>The prevalence of obesity is rising globally. Evidence-informed guidance on preventing obesity is needed, but most existing obesity guidelines are focussed on treatment.</p><p><strong>Methods: </strong>We developed an evidence- and consensus-based guideline on the prevention of obesity among adults. Following international best practice recommendations for guideline development, we systematically searched for relevant systematic reviews and conducted a structured consensus process involving 34 experts including 5 patient representatives. The guideline's target group is the adult population of Germany, but most recommendations are likely to be applicable internationally.</p><p><strong>Results: </strong>We developed 24 recommendations for the general public, health care professionals, and policy makers. The guideline recommends, among others, a healthy diet in line with existing food-based dietary guidelines, regular physical activity, as well as appropriate sleep and stress management. Smoking cessation is recommended even when associated with weight gain. Offering qualified advice and counselling on diet and physical activity to all individuals in primary care is suggested. Potential effects of medication on body weight should be considered in prescription decisions. Implementation of evidence-informed policies for promoting healthy food and physical activity environments is recommended.</p><p><strong>Conclusions: </strong>Evidence-based approaches for preventing obesity on the individual and societal levels exist and should be implemented more widely.</p>","PeriodicalId":19414,"journal":{"name":"Obesity Facts","volume":" ","pages":"1-19"},"PeriodicalIF":3.9,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12215444/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144128210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ten Top Tips for the Management of GLP-1 Receptor Agonists in Adults within Primary Care. 初级保健中GLP-1受体激动剂管理的10个重要提示。
IF 4.7 3区 医学
Obesity Facts Pub Date : 2025-05-19 DOI: 10.1159/000546472
Laurence J Dobbie, Helen M Parretti, Ellen Fallows, Sarah Le Brocq, Stephanie De Giorgio, Barbara McGowan, Dipesh Patel
{"title":"Ten Top Tips for the Management of GLP-1 Receptor Agonists in Adults within Primary Care.","authors":"Laurence J Dobbie, Helen M Parretti, Ellen Fallows, Sarah Le Brocq, Stephanie De Giorgio, Barbara McGowan, Dipesh Patel","doi":"10.1159/000546472","DOIUrl":"10.1159/000546472","url":null,"abstract":"","PeriodicalId":19414,"journal":{"name":"Obesity Facts","volume":" ","pages":"1-6"},"PeriodicalIF":4.7,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12194299/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144102326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Association between Obesity and Wet Overactive Bladder: Results from 2005 to 2020 National Health and Nutrition Examination Survey. 肥胖与湿性膀胱过动症的关系:2005-2020年全国健康与营养调查结果
IF 3.9 3区 医学
Obesity Facts Pub Date : 2025-05-11 DOI: 10.1159/000546104
Jiahao Zhang, Wanru Chen, Zhicheng Tang, Xuqing Lin, Xitong Wan, Shuqiang Huang, Hongcheng Luo, Yuxin Qian, Zhaohui He, Fucai Tang
{"title":"The Association between Obesity and Wet Overactive Bladder: Results from 2005 to 2020 National Health and Nutrition Examination Survey.","authors":"Jiahao Zhang, Wanru Chen, Zhicheng Tang, Xuqing Lin, Xitong Wan, Shuqiang Huang, Hongcheng Luo, Yuxin Qian, Zhaohui He, Fucai Tang","doi":"10.1159/000546104","DOIUrl":"10.1159/000546104","url":null,"abstract":"<p><strong>Introduction: </strong>The association between obesity and wet overactive bladder (wet OAB) was few and was also inconsistent and controversial in sex differences. This study aimed to ascertain the specific association between obesity and wet OAB for females and males using five obesity measures.</p><p><strong>Methods: </strong>This cross-sectional study included 29,041 participants from the 2005-2020 National Health and Nutrition Examination Survey database. The outcome was the risk of wet OAB. Five obesity measures were exposure using quintile, including body mass index (BMI), waist-to-stature ratio (WSR), body fat percentage (BFP), fat mass, and lean mass. The associations were elucidated using weighted logistic regression models and restricted cubic spline (RCS) analysis.</p><p><strong>Results: </strong>The elevated BMI, WSR, BFP, and fat mass were positively associated with the risk of wet OAB in both sexes, which was evident in females. Interestingly, lean mass was adversely associated with the risk of wet OAB in both sexes. In RCS analysis about BMI, WSR, BFP, and fat mass, monotonically increasing nonlinear associations were found in males, while positive linear associations were found in females. Besides, negative linear and nonlinear relationships were shown between lean mass and the risk of wet OAB in females and males, respectively.</p><p><strong>Conclusions: </strong>Obesity was positively associated with the risk of wet OAB in both sexes. Controlling BMI, WSR, BFP, fat mass, and strengthening lean mass may help prevent the development of wet OAB.</p>","PeriodicalId":19414,"journal":{"name":"Obesity Facts","volume":" ","pages":"1-14"},"PeriodicalIF":3.9,"publicationDate":"2025-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12176402/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144030189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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