Nutrition and Metabolic Insights最新文献

{"title":"Dietary Diversity and Nutritional Status of Adolescents in Rural Ghana.","authors":"Michael Akenteng Wiafe,&nbsp;Charles Apprey,&nbsp;Reginald Adjetey Annan","doi":"10.1177/11786388231158487","DOIUrl":"https://doi.org/10.1177/11786388231158487","url":null,"abstract":"<p><strong>Background: </strong>The rapid biological and physical changes during adolescence require adequate nutrient intake. This study assessed dietary diversity and nutritional status of adolescents living in selected rural areas in Ghana.</p><p><strong>Method: </strong>In this cross-sectional study, 137 young adolescents, aged 10 to 14 years were recruited. Structured questionnaire was used to collect data on sociodemographic, household size and food intake practices. A multiple past 24-hour recall was used to estimate the micronutrients intake. Haemoglobin and anthropometry data were assessed. Dietary diversity score was assessed with 10 food groups described by Food and Agricultural Organization. Descriptive, chi-square, binary regression and partial correlation were used in the data analysis.</p><p><strong>Results: </strong>The prevalence of underweight was 5.5%, overweight 5.8% and anaemia 29.9%. The mean dietary diversity score was 3.8 ± 0.8 and about 84.7% of participants had inadequate dietary diversity. Proportions of adolescents who consumed from the different food groups over a 24-hour period were: grains, white roots and tubers, plantain (100%); pulses (10.2%); nuts and seeds (34.1%); dairy (8%); meat, poultry and fish (86.9%); eggs (7.3%); dark green leafy vegetables (29.9%); other vitamin-A rich fruits and vegetables (2.2%); other vegetables (81%); other fruits (7.3%). Dietary diversity scores were positively and significantly correlated with intake of micronutrient, with correlation coefficients of .169, .186, .191, .173 and .175 for vitamin A, niacin, vitamin B₆, iron and zinc, respectively. Meal skipping (AOR = 12.2, <i>P</i> < .001, 95% CI: 3.6-41.7) and snacking (AOR = 5.0, <i>P</i> = .007, 95% CI:1.6-16.7) increased odds of inadequate dietary diversity.</p><p><strong>Conclusion: </strong>The high prevalence of inadequate dietary diversity was positively related to meal skipping and snacking among adolescents. Dietary diversity score was significantly related to the intake of vitamin A, niacin, vitamin B₆, iron and zinc. The prevalence of anaemia among our study participants is of public health concern. Adolescents should be encouraged both at home and school to eat from diverse food groups to promote adequate intake of micronutrients.</p>","PeriodicalId":19396,"journal":{"name":"Nutrition and Metabolic Insights","volume":"16 ","pages":"11786388231158487"},"PeriodicalIF":1.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/fc/52/10.1177_11786388231158487.PMC10009014.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9179999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Buffalo Milk Consumption on the Growth of 10 to 12 years Old Schoolgirls in Magdalena, Laguna, Philippines.","authors":"Marivic S Samson,&nbsp;Corazon Vc Barba,&nbsp;Leila S Africa,&nbsp;Juliet S Aguilar,&nbsp;Merlyene M Paunlagui,&nbsp;Agnes C Rola,&nbsp;Kristine R Vigilla-Montecillo,&nbsp;Thelma A Saludes,&nbsp;Arnel N Del Barrio","doi":"10.1177/11786388231151355","DOIUrl":"https://doi.org/10.1177/11786388231151355","url":null,"abstract":"<p><strong>Background: </strong>Milk contains essential nutrients that help can improve the growth and development of adolescent girls.</p><p><strong>Objectives: </strong>The study determined the effect of milk consumption on the nutritional status of schoolgirls ages 10 to 12 years old in Magdalena, Laguna, Philippines.</p><p><strong>Methodology: </strong>A quasi-experimental study design was used to determine the impact of daily consumption of 200 ml buffalo milk on the prevalence of undernutrition among the 57 schoolgirl participants before and after 160 days. One sample <i>t</i>-test and paired <i>t</i>-test were used to compare the actual and expected total increment and monthly changes in the height and body mass index (BMI) of the participants, while a one-way analysis of variance was used to compare the actual total changes in height and BMI by age. Factors that are correlated with these measurements were identified based on Spearman's correlation coefficients.</p><p><strong>Results: </strong>The percentage of stunting (31.6%-22.8%) and thinness (21.1%-15.8%) decreased after the milk feeding. Significant differences were observed in the means of total actual and expected changes in height (<i>P</i> < .00) and BMI (<i>P</i> < .00). While there were significant differences in the means of actual and expected monthly changes in height every month, this was only observed in the first 2 months for BMI. Only the mean actual changes in height had significant differences when compared by age (<i>P</i> = .04). Lastly, the age and education of the father were found to be correlated with the height of the schoolgirls.</p><p><strong>Conclusion: </strong>Buffalo milk consumption can improve the growth outcomes of schoolgirls.</p>","PeriodicalId":19396,"journal":{"name":"Nutrition and Metabolic Insights","volume":"16 ","pages":"11786388231151355"},"PeriodicalIF":1.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/1f/9e/10.1177_11786388231151355.PMC10184191.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10290165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nutritional Status of Postpartum Mothers and Associated Risk Factors in Shey-Bench District, Bench-Sheko Zone, Southwest Ethiopia: A Community Based Cross-Sectional Study.","authors":"Asresash Sebeta, Abel Girma, Rediet Kidane, Eyob Tekalign, Dessalegn Tamiru","doi":"10.1177/11786388221088243","DOIUrl":"10.1177/11786388221088243","url":null,"abstract":"<p><strong>Background: </strong>Malnutrition affects millions of people in developing countries and contributes to poor health outcomes and nutritional status among women in the postpartum period. Lactation increases high nutritional demands and marks a significant life transition that can impact diet quality and subsequently predispose woman to high risk of overweight and undernutrition. Although, studies have been conducted on the nutritional status of lactating women, there is a gap especially on women's nutritional status during the postpartum period. Therefore, this study aimed to assess the nutritional status of postpartum women and associated factors in Shey-Bench District, Bench-Sheko Zone, Southwest Ethiopia, 2020.</p><p><strong>Method: </strong>A community-based cross-sectional study was conducted in Shey-Bench District from March 1 to 30/2020 among 359 postpartum mothers. Bivariate analysis was employed to select candidate variables at <i>P</i>-value <.25 as a cut-off point. Multiple multinomial logistic regression analysis was used to identify variables significantly associated with nutritional status of the mother at <i>P</i> < .05 with 95% CI.</p><p><strong>Results: </strong>The study revealed that 10.3% of women were underweight and 16.7% were overweight. Employed mothers (AOR = 4.467, 95% CI [1.05-19.04]), employed husband (AOR = 0.087, 95% CI [0.021-0.370]), farmer husband (AOR = 0.084, 95% CI [0.024-0.293]), trader husband (AOR = 0.19, 95% CI [0.0614-0.616]), married mother (AOR = 0.222, 95% CI [0.088-0.560]), dietary diversity (AOR = 0.181, 95% CI [0.075-0.436]) were significantly associated with underweight and while being overweight was associated with dietary diversity, maternal age of between 15 to 24 and 25 to 34, exclusive breastfeeding, and frequency of breastfeeding.</p><p><strong>Conclusion: </strong>This study found a lower prevalence of underweight compared with overweight in the study area. Occupational status, marital status, age of the mother, dietary diversity, exclusive and frequency of breastfeeding were significantly associated factors with nutritional status of postpartum mother. We recommend strengthening the provision of nutrition education on modifiable factors with collaboration of other sectors.</p>","PeriodicalId":19396,"journal":{"name":"Nutrition and Metabolic Insights","volume":"15 1","pages":"11786388221088243"},"PeriodicalIF":2.3,"publicationDate":"2022-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044780/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42285838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lifestyle Modification Practice and Associated Factors Among Diagnosed Hypertensive Patients in Selected Hospitals in Central Gondar Zone","authors":"Moges Smachew, Melkitu Fentie Melak, Azeb Atenafu, Aysheshim Kassahun Belew","doi":"10.1177/11786388221088245","DOIUrl":"https://doi.org/10.1177/11786388221088245","url":null,"abstract":"Background: Hypertension is one of the leading causes of disability and death in both developed and developing countries including Ethiopia. Non-communicable diseases account for 42% of deaths in Ethiopia. However, it is still widely undetected and poorly controlled. Hence, this study aims to assess the lifestyle modification practices and related factors of adult hypertensive patients in the central Gondar region of northwestern Ethiopia. Methods: Institutional based, cross-sectional study was conducted from April 10 up to May 10, 2021. A simple random sampling was used to select 629 study participants. Data were collected by using self-administered and structured questionnaire. Data were entered to EpiData 4.6 and exported to SPSS 20 for further analysis. A multivariable logistic regression analysis was employed to identify the factors associated with lifestyle modification. Adjusted Odds Ratio (AOR) with 95% confidence interval was used to show the strength of association, while a P-value <.05 of was used to declare the significance of association. Results: The overall prevalence of recommended lifestyle modification in hypertensive patients was 24.2% (95% CI (20.8, 27.5)). Age ⩾65 years (AOR = 0.59, 95% CI: 0.39, 0.88), no formal education (AOR = 0.65, 95% CI: 0.4, 0.97), diagnosis time is 5 to 10 years (AOR = 1.93, 95% CI: 1.11, 3.34), co morbidities (AOR = 0.47, 95% CI: 0.3, 0.73), and rich wealth index (AOR = 1.99, 95% CI: 1.22, 3.27) are is significantly associated with good lifestyle modification practices. Conclusions: The practice of good lifestyle modifications in the study area was found to be low among the hypertensive patients. Respondents’ age, education status, wealth index, duration of diagnosis, and co morbidities were found to be significant factors related to good lifestyle modification practices. Therefore, more attention should be paid to providing nutrition counseling and health promotion to improve the practice of lifestyle modification in patients with hypertension.","PeriodicalId":19396,"journal":{"name":"Nutrition and Metabolic Insights","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43985207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Myriocin Treatment Reverses Alcohol-Induced Alterations in Polyunsaturated Fatty Acid-Containing Phospholipid Expression in the Liver.","authors":"Emine B Yalcin,&nbsp;Ming Tong,&nbsp;Camilla Homans,&nbsp;Suzanne M de la Monte","doi":"10.1177/11786388221082012","DOIUrl":"https://doi.org/10.1177/11786388221082012","url":null,"abstract":"<p><p>Chronic heavy alcohol exposure causes steatohepatitis manifested by abnormal intra-hepatocyte accumulation of lipid and parenchymal inflammation. Attendant alterations in polyunsaturated fatty acid (PUFA)-containing phospholipids could cause alcoholic liver disease (ALD) to progress by promoting oxidative stress, inflammation, and fibrogenesis. Previously we showed that myriocin, a serine palmitoyltransferase inhibitor, ameliorates experimental alcohol-induced steatohepatitis. However, the surprising overall therapeutic responses suggested that myriocin's targets may go beyond sphingolipids. To this end, the present study examines the effects of myriocin on hepatic composition of docosahexaenoic acid (DHA)- and arachidonic acid (AA)-containing phospholipids in an experimental model of ALD. A chronic+binge ethanol exposure model was generated by feeding Long Evans rats with ethanol-containing diets (24% caloric content) for 8 weeks and simultaneously binge gavage administering 2 g/kg ethanol on Tuesdays, Thursdays and Saturdays during Weeks 6-8. Myriocin was administered by i.p. injection on Mondays, Wednesdays, and Fridays of Weeks 3-8. Control rats were studied in parallel. Upon euthanasia, the livers were harvested to examine ethanol- and/or myriocin-modulation of hepatic lipids using matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI-IMS). Results were analyzed statistically by two-way analysis of variance and depicted with data bar plots and heatmaps. Chronic+binge ethanol exposures significantly increased hepatic expression of AA-containing phospholipids including PE(36:4) (<i>P</i> = .005), PE(38:4) (<i>P</i> = .03), and PI(38:4) (<i>P</i> = .04) and reduced DHA-containing phospholipids including PS(40:6) (<i>P</i> = .03) and PE(40:6) (<i>P</i> = .04) relative to control. Myriocin partially reversed ethanol's effects on hepatic PUFA expression by decreasing PE(36:4) (<i>P</i> = .004) and increasing PS(40:6) (<i>P</i> = .04) and PI(40:6) (<i>P</i> = .0003) relative to ethanol-exposed rats. Ethanol-mediated alterations in hepatic PUFA-containing phospholipids may contribute to hepatic oxidative and inflammatory injury by increasing AA and fibrogenesis by inhibiting DHA. The results suggest that Myriocin may help reduce or prevent long-term and progressive liver injury stemming from excessive chronic+binge ethanol consumption.</p>","PeriodicalId":19396,"journal":{"name":"Nutrition and Metabolic Insights","volume":"15 ","pages":"11786388221082012"},"PeriodicalIF":1.7,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5a/50/10.1177_11786388221082012.PMC8891894.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10634389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Examining the Benefits of Digitally Selectable Meals Called “À La Carte Digital-Select” in Cancer Chemotherapy Patients","authors":"T. Aoyama","doi":"10.1177/11786388221098507","DOIUrl":"https://doi.org/10.1177/11786388221098507","url":null,"abstract":"We explored the benefits of a digitized bedside terminal with a touchscreen for selectable hospital meals called “à la carte digital-select” in cancer chemotherapy patients. The subjects used “à la carte digital-select” for 35 days, from November to December 2015. On average, 253 (between 196 and 288) patients accessed this system per day, and 40 patients used it daily (15.9%). Subjects included 75 patients (cancer chemotherapy: chem-digital-select patients, female: 47) and 12 patients (concurrent chemo radiotherapy: CRT-digital-select patients, female: 6) with a repeat rate of 87% (65) and 100% (12). The average length of hospital stay in chem-digital-select patients was 6 days (1-35), the average number of days using “à la carte digital-select” was 3 days (1-24); a correlation was observed between these factors (r = .80; P < .01). The eating rate of chemotherapy patients and CRT-digital-select patients was high (81%, 81%), and no differences were observed between the rate in the cisplatin group (80%) with 28 patients, the non-cisplatin group (81%) with 47 patients, CRT-digital-select patients (81%) with 12 patients (P = .59; ANOVA). Registered dietitians provided no nutritional intervention in any of the cases. We found that “à la carte digital-select” can contribute to supporting cancer chemotherapy and the dietary needs of cancer patients undergoing chemotherapy.","PeriodicalId":19396,"journal":{"name":"Nutrition and Metabolic Insights","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48784730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Food Creatine and DXA-Derived Body Composition in Boys and Girls Aged 8 to 19 Years.","authors":"Darinka Korovljev,&nbsp;Nikola Todorovic,&nbsp;Valdemar Stajer,&nbsp;Sergej M Ostojic","doi":"10.1177/11786388211059368","DOIUrl":"https://doi.org/10.1177/11786388211059368","url":null,"abstract":"<p><p>Several small-scale trials indicate a positive correlation between dietary creatine intake and fat-free mass in the pediatric population; whether this connection occurs at the population-wide level remains currently unknown. The main purpose of this cross-sectional study was to calculate the amount of creatine consumed through a regular diet among U.S. boys and girls aged 8 to 19 years, and investigate the link between creatine consumption and dual-energy X-ray absorptiometry (DXA)-derived body composition indices in this population. Data were obtained from the National Health and Nutrition Examination Survey 2017-2018 round, with dietary information and whole-body DXA body composition measures extracted for respondents aged 8 to 19 years (1273 participants, 649 boys and 624 girls). Individual values for total grams of creatine consumed per day for each participant were computed using the average amount of creatine (3.88 g/kg) across all creatine-containing foods. The primary exposure was the mean daily intake of creatine; the primary and secondary outcomes comprised lean mass excluding bone mineral content (BMC), and bone mineral density, BMC, lean mass including BMC, fat mass, and percent body fat, respectively. The average intake of creatine across the sample was 0.65 ± 0.72 g/day (95% CI, from 0.61 to 0.69). Creatine positively correlated with lean mass (excluding BMC) and BMC across the whole sample (<i>r</i> = .18 and .20, respectively; <i>P</i> < .001); a significant negative correlation was found between creatine intake and percent body fat (<i>r</i> = -.09; <i>P</i> = .001). The higher intake of creatine was associated with higher lean mass in girls and higher BMC in boys, while taking more creatine corresponded to less body fat for both genders (<i>P</i> < .05). Our findings indicate a significant correlation between dietary creatine and DXA-derived body composition biomarkers in a nationally representative cohort of U.S. youth. These results justify further research of creatine's role in modifying body morphology in the pediatric population, taking into account the age and sex specific traits.</p>","PeriodicalId":19396,"journal":{"name":"Nutrition and Metabolic Insights","volume":"14 ","pages":"11786388211059368"},"PeriodicalIF":1.7,"publicationDate":"2021-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/83/6e/10.1177_11786388211059368.PMC8655826.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39719231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biological Functions and Activities of Rice Bran as a Functional Ingredient: A Review.","authors":"Suwimol Sapwarobol,&nbsp;Weeraya Saphyakhajorn,&nbsp;Junaida Astina","doi":"10.1177/11786388211058559","DOIUrl":"https://doi.org/10.1177/11786388211058559","url":null,"abstract":"<p><p>Rice bran (RB) is a nutrient-rich by-product of the rice milling process. It consists of pericarp, seed coat, nucellus, and aleurone layer. RB is a rich source of a protein, fat, dietary fibers, vitamins, minerals, and phytochemicals (mainly oryzanols and tocopherols), and is currently mostly used as animal feed. Various studies have revealed the beneficial health effects of RB, which result from its functional components including dietary fiber, rice bran protein, and gamma-oryzanol. The health effects of RB including antidiabetic, lipid-lowering, hypotensive, antioxidant, and anti-inflammatory effects, while its consumption also improves bowel function. These health benefits have drawn increasing attention to RB in food applications and as a nutraceutical product to mitigate metabolic risk factors in humans. This review therefore focuses on RB and its health benefits.</p>","PeriodicalId":19396,"journal":{"name":"Nutrition and Metabolic Insights","volume":"14 ","pages":"11786388211058559"},"PeriodicalIF":1.7,"publicationDate":"2021-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/71/fb/10.1177_11786388211058559.PMC8655829.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39719230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the Utility of Amino Acid Citrulline as a Surrogate Metabolomic Biomarker for the Diagnosis of Celiac Disease.","authors":"Avinash Lomash, Anupa Prasad, Raghvendra Singh, Somesh Kumar, Rishi Gupta, Dhwani Dholakia, Praveen Kumar, Vineeta V Batra, Amarender S Puri, Seema Kapoor","doi":"10.1177/11786388211060603","DOIUrl":"10.1177/11786388211060603","url":null,"abstract":"<p><strong>Introduction: </strong>Citrulline is regarded as a biomarker for celiac disease (CD). Its utility for assessment and evaluation of additive predictive value for latent, potential CD and first degree relatives (FDRs) needs exploration.</p><p><strong>Method: </strong>Consecutive 558 index cases diagnosed as per European Society for Pediatric Gastroenterology and Nutrition (ESPGHAN) 2012 guidelines and their 1565 FDRs were evaluated over five and half year period. Serology negative FDRs at initial visit and follow ups were served as controls. HLA typing for DQ2 and DQ8 genotypes, along with plasma and dried blood spot (DBS) filter paper citrulline were evaluated.</p><p><strong>Results: </strong>Median plasma citrulline values were 20.1 and 37.33 µMol/l in cases and controls (<i>P</i> < .001). Cut off values for Marsh grade 3a, 3b, and 3c were 35.0, 32.8, 25.26 µMol/l in CD patients and 36.51, 30.10, 25.26 µMol/l in biopsy proven FDR. Increasing trends of plasma citrulline levels with decreasing tTG-IgA levels were observed on follow up. Low plasma citrulline levels were observed with HLA DQ 2.5 genotype (<i>P</i> < .05). Agreement between DBS and plasma citrulline was 94.8%.</p><p><strong>Conclusion: </strong>Citrulline is a good surrogate biomarker for identification of histopathological grade of damage, extent of mucosal recovery and has negative correlation with tTG-IgA. It identifies the silent and latent phase of CD. DBS citrulline provides adequate information and can be used for monitoring CD patients at remote locations.</p>","PeriodicalId":19396,"journal":{"name":"Nutrition and Metabolic Insights","volume":"14 ","pages":"11786388211060603"},"PeriodicalIF":2.3,"publicationDate":"2021-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2d/1a/10.1177_11786388211060603.PMC8655831.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39719232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dietary Practice and Associated Factors Among Pregnant Women at Public Health Institution in Mizan-Aman Town, Southwest Ethiopia.","authors":"Abel Girma Tilahun,&nbsp;Abebaw Molla Kebede,&nbsp;Amare Genetu Ejigu","doi":"10.1177/11786388211057796","DOIUrl":"https://doi.org/10.1177/11786388211057796","url":null,"abstract":"<p><strong>Background: </strong>A poor dietary intake of key macronutrients and micronutrients adversely affects pregnancy outcomes and neonatal health. The occurrence of dietary inadequacy during pregnancy is higher compared to any other stage of the life cycle. Therefore, this study aimed to assess dietary practice and associated factors among pregnant women.</p><p><strong>Methods: </strong>A facility-based cross-sectional study design was conducted among 378 pregnant women from March to May 2021 at the public health institution of Mizan-Aman town, southwest Ethiopia. A systematic random sampling technique was used to reach the study participants. The short food-frequency questionnaires and nutrition-behaviors checklist measurement were used to assess the dietary practice. Nine questions were applied to assess the dietary attitudes of the respondents. After the summation of the score, the respondent was categorized as favorable attitude if their score was > the median and unfavorable attitude if their score was ⩽ to the median of the score. The data were entered into Epi Data 3.1 and exported to Statistical Package for Social Science (SPSS) version 21 software for analysis. Variables of <i>P</i>-value <.25 during bivariate logistic regression analysis were considered for multivariate analysis. Finally variables with an adjusted odds ratio of <i>P</i>-value <.05 along with a 95% Confidence interval (CI) were declared statistically significant.</p><p><strong>Results: </strong>The overall magnitude of good dietary practice among pregnant women was 25.1% (95% CI: 20.9, 29.71%). In multivariate logistic regression analysis, the variables having television/radio (AOR = 4.2, 95% CI: 1.8, 10.2), household food security (AOR = 3.1, 95% CI: 1.0, 9.9), good dietary knowledge(AOR = 4.1, 95% CI: 1.98, 8.6), favorable dietary attitude (AOR = 4.34, 95% CI: 1.2, 8.7), monthly income of 1000 to 2000 Ethiopian birr (AOR = 3.7, 95% CI: 1.3,11.2) and >2000 Ethiopian birr (AOR = 7.0;95% CI: 3.3,15.4) were significantly associated with good dietary practice.</p><p><strong>Conclusion: </strong>The dietary practice among pregnant women was very low. The factors like having television/radio, good dietary knowledge, household food security, favorable dietary attitude, and monthly income of 1000 to 200 and greater than 2000 Ethiopian birr were significantly associated with the good dietary practice of pregnant women.</p>","PeriodicalId":19396,"journal":{"name":"Nutrition and Metabolic Insights","volume":"14 ","pages":"11786388211057796"},"PeriodicalIF":1.7,"publicationDate":"2021-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a7/0a/10.1177_11786388211057796.PMC8606983.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39923205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}