NPJ Science of Food最新文献_第6页

Fructooligosaccharides and Aspergillus enzymes increase brain GABA and homocarnosine by modulating microbiota in adolescent mice. 低聚果糖和曲霉酶通过调节青春期小鼠的微生物群增加脑GABA和同型肌肽。

IF 6.3 1区农林科学

NPJ Science of Food Pub Date : 2025-04-03 DOI: 10.1038/s41538-025-00383-1

Jason D Braga, Yongshou Yang, Tomoka Nagao, Norihisa Kato, Noriyuki Yanaka, Kyoichi Nishio, Masamichi Okada, Manabu Kuroda, Shotaro Yamaguchi, Thanutchaporn Kumrungsee

{"title":"Fructooligosaccharides and Aspergillus enzymes increase brain GABA and homocarnosine by modulating microbiota in adolescent mice.","authors":"Jason D Braga, Yongshou Yang, Tomoka Nagao, Norihisa Kato, Noriyuki Yanaka, Kyoichi Nishio, Masamichi Okada, Manabu Kuroda, Shotaro Yamaguchi, Thanutchaporn Kumrungsee","doi":"10.1038/s41538-025-00383-1","DOIUrl":"10.1038/s41538-025-00383-1","url":null,"abstract":"Recent research suggests that dietary prebiotics, probiotics, or healthy fecal-microbiota transplantation attenuate gut microbiota dysbiosis and ameliorate neurological disorders, in which gut-microbiota-derived γ-aminobutyric acid (GABA) has gained much attention as one of key mediators in the gut-brain axis. Although it is widely accepted that prebiotics and probiotics induce gut and brain GABA production via modulating gut microbiota, only evidence of probiotics has been solidly demonstrated while this evidence of prebiotics is scarce. Here, we demonstrated that prebiotic fructo-oligosaccharides and Aspergillus-derived enzymes elevated gut and brain GABA concentrations by modulating gut microbiota. Interestingly, we found that the prebiotic and enzymes increased a brain-specific dipeptide, homocarnosine. Gut GABA levels were found correlated with brain GABA/homocarnosine levels. Parabateroides, Akkermansia, Muribaculum, Hungatella, Marvinbryantia, Flavonifractor, and Incertae_sedis exhibited a positive correlation with gut GABA and brain GABA/homocarnosine levels, while Blautia, Unclassified_Lachnospiraceae, Colidextribacter, Acetatifactor, Roseburia, Unclassified_Oscillospiraceae, Romboutsia, and Eubacterium_coprostanoligenes exhibited a negative correlation with those levels.","PeriodicalId":19367,"journal":{"name":"NPJ Science of Food","volume":"9 1","pages":"48"},"PeriodicalIF":6.3,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11965294/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143772856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of acute low intensity aerobics and blueberry juice on arterial stiffness in young adults. 急性低强度有氧运动和蓝莓汁对青壮年动脉僵硬的影响。

IF 6.3 1区农林科学

NPJ Science of Food Pub Date : 2025-04-01 DOI: 10.1038/s41538-025-00408-9

Ruisi Wu, Huali Yu, Jiayuan Xu, Zhiqiang Tan, Yongsheng Lan, Dongfang Shi

{"title":"Effects of acute low intensity aerobics and blueberry juice on arterial stiffness in young adults.","authors":"Ruisi Wu, Huali Yu, Jiayuan Xu, Zhiqiang Tan, Yongsheng Lan, Dongfang Shi","doi":"10.1038/s41538-025-00408-9","DOIUrl":"10.1038/s41538-025-00408-9","url":null,"abstract":"Arterial stiffness, a cardiovascular disease (CVD) predictor starting from youth, is under-researched in young adults. Low-intensity aerobic exercise (LAE) is generally more accessible than higher-intensity exercise and may be more sustainable for young individuals. Blueberries, renowned for vascular health benefits, may reduce arterial stiffness. This study examines the effects of LAE and blueberry juice on arterial stiffness in 48 young adults. Participants were randomized into LAE, low-, mid-, or high-volume blueberry juice (LB, MB, HB), LAE + LB, LAE + MB, LAE + HB, and control groups. Arterial stiffness was measured at baseline and at 15-, 30-, 45-, and 60 min post-intervention. Blood samples were collected pre-intervention and 30-min post-intervention for metabolomic analysis. Repeated ANOVA revealed LAE + MB significantly reduced arterial stiffness. Metabolomic analysis revealed changes in linoleic acid, sphingolipid, phenylalanine, nicotinate and nicotinamide, glycerophospholipid, and lysine degradation metabolic pathways. These findings suggest a feasible exercise-diet strategy for CVD prevention in young adults and provide metabolic insights into the mechanisms.","PeriodicalId":19367,"journal":{"name":"NPJ Science of Food","volume":"9 1","pages":"47"},"PeriodicalIF":6.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11962078/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143764358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dynamic membrane changes and osmotic effects by sugar alcohols. 糖醇的动态膜变化及渗透效应。

IF 6.3 1区农林科学

NPJ Science of Food Pub Date : 2025-03-30 DOI: 10.1038/s41538-025-00410-1

Lichun Chen, Feng Yao, Songwen Xue, Kuang Yao, Yun Huang, Huimin Zhao, Qiong Shao

{"title":"Dynamic membrane changes and osmotic effects by sugar alcohols.","authors":"Lichun Chen, Feng Yao, Songwen Xue, Kuang Yao, Yun Huang, Huimin Zhao, Qiong Shao","doi":"10.1038/s41538-025-00410-1","DOIUrl":"10.1038/s41538-025-00410-1","url":null,"abstract":"Sugar alcohols are natural sweeteners with various physiological functions, commonly used in low-calorie foods and pharmaceuticals. Current research primarily focuses on their sweetening properties and metabolic effects, often overlooking their interactions with cell membranes. This study built a giant phospholipid vesicle model to examine vesicle deformation in erythritol (Ery) and xylitol (Xyl) environments. The permeation of these sugar alcohols through real cell membranes was also investigated. Fluorescence microscopy and zeta potential measurements showed that osmotic stress from concentration gradients disrupted vesicle membrane structure. Ery and Xyl reduced ROS levels in HEK-293 cells and influenced membrane permeability. Notably, Xyl increased vesicle adsorption on the cell membrane at the same concentration. The findings indicate that sugar alcohols interact with membrane lipids through hydrogen bonds or other non-covalent interactions, modifying cell membrane structure and properties, thus providing a theoretical foundation for understanding their role in physiological environments.","PeriodicalId":19367,"journal":{"name":"NPJ Science of Food","volume":"9 1","pages":"46"},"PeriodicalIF":6.3,"publicationDate":"2025-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11955526/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143753866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Metabolomics and sensory evaluation combined analysis reveal the effect of processing methods and different forms on the flavor of rose herbal tea. 代谢组学和感官评价相结合的分析揭示了加工方法和不同形式对玫瑰凉茶风味的影响。

IF 6.3 1区农林科学

NPJ Science of Food Pub Date : 2025-03-29 DOI: 10.1038/s41538-025-00387-x

Yue Zhao, Qunhua Peng, Lu Chang, Zhe Wang, Zhi Lin, Jiang Shi, Chunwang Dong

{"title":"Metabolomics and sensory evaluation combined analysis reveal the effect of processing methods and different forms on the flavor of rose herbal tea.","authors":"Yue Zhao, Qunhua Peng, Lu Chang, Zhe Wang, Zhi Lin, Jiang Shi, Chunwang Dong","doi":"10.1038/s41538-025-00387-x","DOIUrl":"10.1038/s41538-025-00387-x","url":null,"abstract":"Pingyin rose herbal tea is favored in the market for its unique quality and health benefits. Thus, researchers have explored a range of different rose products. This study evaluated the effect of processing methods and different forms on the flavor of rose herbal tea combined with sensory evaluation and metabolite profiles. Sensory evaluation showed that low-temperature drying (LTD) roses have a distinct floral and sweet aroma, while vacuum freeze drying (VFD) roses exhibit a fruity and woody aroma. Metabolomics analysis indicated that each type of rose herbal tea has its characteristic accumulation of non-volatile compounds and volatile organic compounds (VOCs). The VFD rose corollas had the highest contents of AAs, OAs, SSs, flavonoids, and VOCs. Furthermore, correlation analysis revealed key nonvolatile and volatile compounds related to aroma and taste. This study provides a scientific foundation for future investigations on the processing and quality improvement of rose herbal tea.","PeriodicalId":19367,"journal":{"name":"NPJ Science of Food","volume":"9 1","pages":"45"},"PeriodicalIF":6.3,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11954921/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143743208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multiomics reveals the molecular mechanism of unsaturated fatty acid-induced terpenoid biosynthesis in Sanghuangporus lonicericola. 多组学揭示了不饱和脂肪酸诱导桑黄芽孢菌萜类生物合成的分子机制。

IF 6.3 1区农林科学

NPJ Science of Food Pub Date : 2025-03-26 DOI: 10.1038/s41538-025-00407-w

Lu Guo, Yuan-Gen Liu, Ying-Wen Fu, Yu-Yan Wang, Hao-Jin Wang, Shu-Mei Zhu, Qi-Zhi He, Dong-Xue Zhang, Shan-Shan Zhu, Si-Xian Wang, Tian Tong, Xu-Jie Dong, Xiao-Ling Wang, Yong-Nan Liu, Gao-Qiang Liu

{"title":"Multiomics reveals the molecular mechanism of unsaturated fatty acid-induced terpenoid biosynthesis in Sanghuangporus lonicericola.","authors":"Lu Guo, Yuan-Gen Liu, Ying-Wen Fu, Yu-Yan Wang, Hao-Jin Wang, Shu-Mei Zhu, Qi-Zhi He, Dong-Xue Zhang, Shan-Shan Zhu, Si-Xian Wang, Tian Tong, Xu-Jie Dong, Xiao-Ling Wang, Yong-Nan Liu, Gao-Qiang Liu","doi":"10.1038/s41538-025-00407-w","DOIUrl":"10.1038/s41538-025-00407-w","url":null,"abstract":"Treatment with C18:1 and C18:2, but not C18:0, increased the triterpenoid content of the medicinal fungus Sanghuangporus lonicericola. We identified 413 terpenoids, including 210 volatile terpenoids. Eight upregulated terpenoids, including 3,13,15-trihydroxyoleanane-12-one, dulcioic acid and serrat-14-ene-3,20,24,29-tetrol, were shared between the C18:1 and C18:2 treatments but not the C18:0 treatment. The C18:1 and C18:2 treatments increased the levels of 12 and 7 odour-related terpenoids, respectively, and increased the level of alpha-farnesene (herbal odour). Gene set enrichment analysis revealed that compared with C18:0, C18:1 and C18:2 produced stronger activation of the terpenoid biosynthesis, fatty acid degradation, and MAPK signalling pathways and stronger inhibition of basal transcription factors at both the transcript and protein levels. Finally, two-way orthogonal partial least squares analysis revealed that gene and protein expression in the identified pathways was correlated with levels of unsaturated fatty acid-induced terpenoid metabolites. Together, our integrated multiomics data revealed the key pathways involved in unsaturated fatty acid-induced terpenoid biosynthesis in S. lonicericola.","PeriodicalId":19367,"journal":{"name":"NPJ Science of Food","volume":"9 1","pages":"44"},"PeriodicalIF":6.3,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11947136/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143720435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhancing blueberry wine quality and antioxidant capacity through mixed fermentation with S. cerevisiae and O. oeni. 用酿酒酵母和欧氏酵母混合发酵提高蓝莓酒的品质和抗氧化能力。

IF 6.3 1区农林科学

NPJ Science of Food Pub Date : 2025-03-26 DOI: 10.1038/s41538-024-00363-x

Kai Liu, Yinyin Lian, Xingyun Xie, Yuyang Gao, Jiajia Song, Huayi Suo, Yu Zhang

{"title":"Enhancing blueberry wine quality and antioxidant capacity through mixed fermentation with S. cerevisiae and O. oeni.","authors":"Kai Liu, Yinyin Lian, Xingyun Xie, Yuyang Gao, Jiajia Song, Huayi Suo, Yu Zhang","doi":"10.1038/s41538-024-00363-x","DOIUrl":"10.1038/s41538-024-00363-x","url":null,"abstract":"This study investigates the impact of O. oeni on the quality of blueberry wine, employing various analytical methods to determine parameters such as alcohol content, antioxidant capacity, organic acids, amino acids, and volatile components. The results demonstrated that co-inoculation with O. oeni significantly decreased the titratable acidity of blueberry wine. Among the organic acids, the malic acid content of ST and SE groups decreased by (26.24 ± 1.24)% and (35.75 ± 4.02)%, respectively. The main consumed amino acids were aspartate, lysine, and arginine after co-inoculation with O. oeni. Additionally, co-inoculation with O. oeni significantly increased the content of medium-chain fatty acid ethyl esters, especially isoamyl acetate content. The antioxidant capacity of blueberry wine was significantly enhanced by co-inoculation with O. oeni, particularly in terms of measurement of 1,1-diphenyl-2-picryl-hydrazyl (DPPH) clearance. The findings of this study provide a solid basis for improving the quality of blueberry wine and promoting the growth of blueberry wine industry.","PeriodicalId":19367,"journal":{"name":"NPJ Science of Food","volume":"9 1","pages":"43"},"PeriodicalIF":6.3,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11947239/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143719874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multivariate fusion for identification of geographic origins and varieties of coix seed. 薏苡仁地理来源和品种的多元融合鉴定。

IF 6.3 1区农林科学

NPJ Science of Food Pub Date : 2025-03-25 DOI: 10.1038/s41538-025-00389-9

Xing Liu, Kai Fan, Yangyang Lu, Qinxiong Rao, Qicai Zhang, Hao Geng, Zhengwu Wang, Weiguo Song

{"title":"Multivariate fusion for identification of geographic origins and varieties of coix seed.","authors":"Xing Liu, Kai Fan, Yangyang Lu, Qinxiong Rao, Qicai Zhang, Hao Geng, Zhengwu Wang, Weiguo Song","doi":"10.1038/s41538-025-00389-9","DOIUrl":"10.1038/s41538-025-00389-9","url":null,"abstract":"To ensure the authenticity of geographic origins and varieties of coix seeds and their preliminary processed products, this study focused on their viscosity characteristics and stable isotopes before and after gelatinization. The feasibility of identifying coix seed origins from Guizhou and Liaoning, China, and distinguishing between big coix seed (BCS) and small coix seed (SCS) based on viscosity parameters, protein and lipid content, stable isotope ratios and near-infrared spectra was investigated. Significant differences were observed in peak viscosity, trough viscosity, final viscosity, δ2H, and δ18O values between Guizhou and Liaoning coix seeds, as well as between BCS and SCS. Stable isotopic changes before and after gelatinization were consistent, with higher δ18O values in gelatinized coix seeds. PLS-DA models achieved prediction accuracies of 92.00% for Guizhou samples, 88.00% for Liaoning samples, and 84.00% for BCS and SCS, providing effective methods for the large-scale traceability of coix seeds' geographic origins and varieties.","PeriodicalId":19367,"journal":{"name":"NPJ Science of Food","volume":"9 1","pages":"41"},"PeriodicalIF":6.3,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11937292/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143710321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Author Correction: Ginseng glucosyl oleanolate inhibit cervical cancer cell proliferation and angiogenesis via PI3K/AKT/HIF-1α pathway. 作者更正：人参糖基齐墩果酸酯通过PI3K/AKT/HIF-1α途径抑制宫颈癌细胞增殖和血管生成。

IF 6.3 1区农林科学

NPJ Science of Food Pub Date : 2025-03-25 DOI: 10.1038/s41538-025-00382-2

Sitong Liu, Zhiyi Ai, Yue Hu, Guangquan Ren, Junshun Zhang, Ping Tang, Hongyang Zou, Xia Li, Yu Wang, Bo Nan, Yuhua Wang

引用次数: 0

Association between plant-based diets and depressive symptoms among Chinese middle-aged and older adults. 中国中老年人群植物性饮食与抑郁症状的关系

IF 6.3 1区农林科学

NPJ Science of Food Pub Date : 2025-03-25 DOI: 10.1038/s41538-025-00399-7

Li Zhang, Shuai Chen, Lijuan Xu, Sui Tang, Chen Huang, Jin Zhou, Chang-Shu Liu, Sai Wang, Yang Cong, Tingting Li, Liangkai Chen, Wenxue Zhang, Shuang Rong

引用次数: 0

Portable DNA extraction integrated with LAMP-CRISPR/Cas12a technology for on-site detection of Salmonella Typhimurium. 结合LAMP-CRISPR/Cas12a技术的便携式DNA提取技术用于鼠伤寒沙门氏菌的现场检测。

IF 6.3 1区农林科学

NPJ Science of Food Pub Date : 2025-03-24 DOI: 10.1038/s41538-025-00401-2

Liang Zhang, Mengfan Zhang, Xingxing Liu, Jia Wei, Caihong Yin, Nan Wang, Beibei Fan, Yanli Fu, Yanwen Liu, Liangyun Bu, Zhenyue Su, Bo Pang, Jinhua Li, Xiuling Song

{"title":"Portable DNA extraction integrated with LAMP-CRISPR/Cas12a technology for on-site detection of Salmonella Typhimurium.","authors":"Liang Zhang, Mengfan Zhang, Xingxing Liu, Jia Wei, Caihong Yin, Nan Wang, Beibei Fan, Yanli Fu, Yanwen Liu, Liangyun Bu, Zhenyue Su, Bo Pang, Jinhua Li, Xiuling Song","doi":"10.1038/s41538-025-00401-2","DOIUrl":"10.1038/s41538-025-00401-2","url":null,"abstract":"The infection and outbreak of Salmonella typhimurium (S. typhimurium) highlight the need for developing a reliable on-site detection strategy fitting to various settings. However, due to the requirement of specialized instruments and trained personnel, traditional detection methods have to be implemented in laboratories and are not ideal for on-site applications. To achieve a sample-to-answer and field-deployable detection for S. typhimurium, we developed an integrated nucleic acid detection platform combining single-vial of loop-mediated isothermal amplification (LAMP)-clustered regularly interspaced short palindromic repeat (CRISPR)/Cas12a system, portable device and smartphone app. This platform enables the extraction, concentration, and purification of DNA, amplification of the target, and output of visual fluorescent signals within 1 h. With this detection platform, 102 CFU/mL of S. typhimurium in food and environmental matrix was able to be accurately detected. This method demonstrated excellent selectivity. Also, an auxiliary smartphone application was developed to achieve simplified result interpretation. Our method exhibited potential to better control and respond to outbreaks of foodborne diseases, especially in low-resource settings.","PeriodicalId":19367,"journal":{"name":"NPJ Science of Food","volume":"9 1","pages":"39"},"PeriodicalIF":6.3,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11933393/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143701052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0