NPJ Science of Food最新文献

Perforated imprinting on high moisture meat analogue confers long range mechanical anisotropy resembling meat cuts

IF 6.3 1区农林科学

NPJ Science of Food Pub Date : 2024-12-20 DOI: 10.1038/s41538-024-00344-0

Xuanming Lou, Jiahao Wang, Leng Gek Kwang, Hanzhang Zhou, Francesca Yi Teng Ong, Shengyong Ng, Hanry Yu

{"title":"Perforated imprinting on high moisture meat analogue confers long range mechanical anisotropy resembling meat cuts","authors":"Xuanming Lou, Jiahao Wang, Leng Gek Kwang, Hanzhang Zhou, Francesca Yi Teng Ong, Shengyong Ng, Hanry Yu","doi":"10.1038/s41538-024-00344-0","DOIUrl":"10.1038/s41538-024-00344-0","url":null,"abstract":"Meat cuts, when cooked and masticated, separate into fibrous structures because of the long-range mechanical anisotropy (LMA) exhibited by muscle fascicles, which is not fully recapitulated in alternative proteins produced using molecular alignment technology like high moisture extrusion. We have developed a scalable perforated micro-imprinting technology to greatly enhance LMA in high moisture meat analogue (HMMA). By imprinting 1 mm thick HMMA sheets with perforated patterns (optimized by AI), we observed up to 5 × more anisotropic separation of fibrous structures in a one-dimensional pulling LMA analysis, to match the fibrousness of the cooked chicken breast, duck breast, pork loin and beef loin. We stacked and bound imprinted sheets with transglutaminase (TG) to produce imprinted whole-cuts. Controlling fiber separation in the imprinted cuts achieved hardness ranging from 6578 g to 18467 g (2 cm × 2 cm × 1 cm, 50% strain), which matched meats from different species. Imprinted cuts improved meat-like fiber separation over HMMA when masticated, measured by Euclidean distances (0.057 and 0.106 respectively) to animal meat cuts on image features. In sensory evaluation, imprinted cuts improved consumer acceptance by 33.3% and meat-like fibrousness by 20%, by significantly enhancing the HMMA appearance, texture, and mouthfeel.","PeriodicalId":19367,"journal":{"name":"NPJ Science of Food","volume":" ","pages":"1-14"},"PeriodicalIF":6.3,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41538-024-00344-0.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142862477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ginseng glucosyl oleanolate inhibit cervical cancer cell proliferation and angiogenesis via PI3K/AKT/HIF-1α pathway

IF 6.3 1区农林科学

NPJ Science of Food Pub Date : 2024-12-19 DOI: 10.1038/s41538-024-00341-3

Sitong Liu, Zhiyi Ai, Yue Hu, Guangquan Ren, Junshun Zhang, Ping Tang, Hongyang Zou, Xia Li, Yu Wang, Bo Nan, Yuhua Wang

{"title":"Ginseng glucosyl oleanolate inhibit cervical cancer cell proliferation and angiogenesis via PI3K/AKT/HIF-1α pathway","authors":"Sitong Liu, Zhiyi Ai, Yue Hu, Guangquan Ren, Junshun Zhang, Ping Tang, Hongyang Zou, Xia Li, Yu Wang, Bo Nan, Yuhua Wang","doi":"10.1038/s41538-024-00341-3","DOIUrl":"10.1038/s41538-024-00341-3","url":null,"abstract":"Ginseng (Panax ginseng C.A. Meyer) is widely used in several functional foods at present. Ginsenosides, is the most crucial bioactive constituents in ginseng whose antitumor activity have been widely reported. In this study, the effect of ginseng glucosyl oleanolate (GGO) produced from ginsenoside Ro through enzymatic transformation, on cervical cancer was evaluated in vitro and in vivo. GGO significantly inhibited the viability and colony forming ability of HeLa cells, and blocked the cell cycle in G0/G1 phase, which showed its ability to inhibit the proliferation of HeLa cells. GGO exhibited anti-angiogenesis effect in HUVECs, chick chorioallantoic membrane (CAM) and Matrigel plugs model. These effects were related to interference with the paracrine axis of VEGF/VEGFR2 and blockage of the downstream PI3K/AKT/HIF-1α signaling pathway of the autocrine axis. The dual inhibitory effects of GGO were also exhibited in immunocompromised mice undergoing heterograft and suppressed tumor growth without any side effects. These findings provide a theoretical basis for further development of GGO as a functional food with anti-tumor properties.","PeriodicalId":19367,"journal":{"name":"NPJ Science of Food","volume":" ","pages":"1-13"},"PeriodicalIF":6.3,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41538-024-00341-3.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142862452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vitamin A stability during storage of fortified gari produced using different fortification strategies 采用不同强化策略生产的强化加里酱在储存期间的维生素 A 稳定性

IF 6.3 1区农林科学

NPJ Science of Food Pub Date : 2024-12-19 DOI: 10.1038/s41538-024-00350-2

Eline Van Wayenbergh, Abena A. Boakye, Jolien Baert, Niels A. Langenaeken, William O. Appaw, Imogen Foubert, Ibok N. Oduro, Christophe M. Courtin

引用次数: 0

Bioconversion of aflatoxin-contaminated groundnut press cake by larvae of black soldier fly Hermetia illucens results in a complete mass balance for aflatoxin B1 黑刺蝇幼虫对受黄曲霉毒素污染的花生压榨饼的生物转化导致黄曲霉毒素 B1 的完全质量平衡

IF 6.3 1区农林科学

NPJ Science of Food Pub Date : 2024-12-19 DOI: 10.1038/s41538-024-00351-1

K. Niermans, S. P. Salari, J. Carney, E. F. Hoek-van den Hil, H. J. van der Fels-Klerx, J. J. A. van Loon

{"title":"Bioconversion of aflatoxin-contaminated groundnut press cake by larvae of black soldier fly Hermetia illucens results in a complete mass balance for aflatoxin B1","authors":"K. Niermans, S. P. Salari, J. Carney, E. F. Hoek-van den Hil, H. J. van der Fels-Klerx, J. J. A. van Loon","doi":"10.1038/s41538-024-00351-1","DOIUrl":"10.1038/s41538-024-00351-1","url":null,"abstract":"Groundnuts are considered as one of the most important cultivated food crops globally. Groundnuts are used for vegetable oil production, which generate a variety of by-products, such as peanut press cake (PPC). Groundnuts are sensitive to infection by aflatoxigenic fungi. Aflatoxins are highly toxic to both humans and livestock, and contaminated crops containing high aflatoxin concentrations are deemed unsafe for consumption and trade. Innovative aflatoxin management strategies are needed and the insect production sector could be such a solution. Larvae of the black soldier fly (BSFL) were exposed to a PPC diet naturally contaminated with aflatoxins. After an exposure lasting eleven days, data on larval survival and biomass were collected. The PPC, BSFL and the residual material were analysed by LC-MS/MS to determine the concentration of eight different aflatoxins. A bio-accumulation factor and a molar mass balance were calculated. BSFL survival and biomass were not affected by exposure to the aflatoxin-contaminated PPC diet. The aflatoxins did not accumulate in the insect body, providing a promising outlook for the safety of rearing insects on aflatoxin contaminated PPC with the purpose of using them as food- and/or feed. Aflatoxin B1 (AFB1) was the dominant compound found in PPC. Formation of aflatoxicol, aflatoxin P1, and aflatoxin M1 occurred and taking these metabolites into account, a complete molar mass balance, thus full recovery, for AFB1 was obtained. This differs from previous studies using artificially spiked substrates in which 17–38% was recovered. This calls for additional studies comparing naturally contaminated with artificially spiked feedstuff.","PeriodicalId":19367,"journal":{"name":"NPJ Science of Food","volume":" ","pages":"1-7"},"PeriodicalIF":6.3,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41538-024-00351-1.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142845260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dietary methionine supplementation improves cognitive dysfunction associated with transsulfuration pathway upregulation in subacute aging mice

IF 6.3 1区农林科学

NPJ Science of Food Pub Date : 2024-12-19 DOI: 10.1038/s41538-024-00348-w

Yuncong Xu, Yuhui Yang, Yonghui Shi, Bowen Li, Yanli Xie, Guowei Le

{"title":"Dietary methionine supplementation improves cognitive dysfunction associated with transsulfuration pathway upregulation in subacute aging mice","authors":"Yuncong Xu, Yuhui Yang, Yonghui Shi, Bowen Li, Yanli Xie, Guowei Le","doi":"10.1038/s41538-024-00348-w","DOIUrl":"10.1038/s41538-024-00348-w","url":null,"abstract":"To explore the effects of methionine (Met) supplementation on cognitive dysfunction and the associated mechanisms in aging mice. The mice were administrated 0.15 g/kg/day D-galactose subcutaneously and fed a normal (0.86% Met) or a Met-supplemented diet (1.72% Met) for 11 weeks. Behavioral experiments were conducted, and we measured the plasma metabolite levels, hippocampal and plasma redox and inflammatory states, and hippocampal transsulfuration pathway-related parameters. Met supplementation prevented aging-induced anxiety and cognitive deficiencies, and normalized the plasma levels of multiple systemic metabolites (e.g., betaine, taurine, and choline). Furthermore, dietary Met supplementation abolished oxidative stress and inflammation, selectively modulated the expression of multiple cognition-related genes and proteins, and increased flux via the transsulfuration pathway in the hippocampi of aging mice, with significant increase in H2S and glutathione production. Our findings suggest that dietary Met supplementation prevented cognitive deficiencies in aging mice, probably because of increased flux via the transsulfuration pathway.","PeriodicalId":19367,"journal":{"name":"NPJ Science of Food","volume":" ","pages":"1-16"},"PeriodicalIF":6.3,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41538-024-00348-w.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142862403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Author Correction: Ampelopsis grossedentata tea alleviating liver fibrosis in BDL-induced mice via gut microbiota and metabolite modulation

IF 6.3 1区农林科学

NPJ Science of Food Pub Date : 2024-12-09 DOI: 10.1038/s41538-024-00347-x

Yi-Yuan Xi, Chen Chen, Ju-Jia Zheng, Bing Jiang, Xin-Ya Dong, Shu-Ying Lou, Jin-Guo Luo, Xiu-Hua Zhang, Zi-Ye Zhou, Qu-Jing Luo, Wei Wang, Xu-Dong Zhou

引用次数: 0

Unlocking the potential of social media on food additives for effective science communication 释放食品添加剂社交媒体的潜力，促进有效的科学传播。

IF 6.3 1区农林科学

NPJ Science of Food Pub Date : 2024-11-25 DOI: 10.1038/s41538-024-00345-z

Ting Lu, Zhaohui Mo, Fangzhou He, Yiping Wang, Zhaoshuo Yu, Li Li, Patrick Wall

{"title":"Unlocking the potential of social media on food additives for effective science communication","authors":"Ting Lu, Zhaohui Mo, Fangzhou He, Yiping Wang, Zhaoshuo Yu, Li Li, Patrick Wall","doi":"10.1038/s41538-024-00345-z","DOIUrl":"10.1038/s41538-024-00345-z","url":null,"abstract":"Ultra-processed foods dominate modern diets, often containing numerous additives to enhance flavor, texture, and shelf life. Concerns about the potential health risks of daily or excessive consumption have sparked online discussions. This study analyzed perceptions of food additives on Zhihu, a popular Chinese social platform. The findings revealed no significant difference in attitudes between experts and non-experts (p > 0.05), with experts relying on statistical data and non-experts drawing from personal experiences. An independent t-test indicated no significance in comment engagement (p > 0.05) among them. However, a chi-square test showed that experts were significantly more interactive, frequently replying directly to original posts and commenters (p < 0.05). This suggests that experts actively facilitate discussions, moving away from reliance on influencers and instead prioritizing high-quality, accessible scientific communication. The findings highlight the crucial role of interactive online platforms in bridging the gap between science and the public.","PeriodicalId":19367,"journal":{"name":"NPJ Science of Food","volume":" ","pages":"1-9"},"PeriodicalIF":6.3,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41538-024-00345-z.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142716452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An ideal leaf spraying strategy of brown sugar for edible medicinal plants of Viola inconspicua 用红糖喷洒食用药用植物 Viola inconspicua 的理想叶片喷洒策略。

IF 6.3 1区农林科学

NPJ Science of Food Pub Date : 2024-11-22 DOI: 10.1038/s41538-024-00343-1

Xuhan Chen, Kemei Wang, Ting Qin, Yachao Bai, Qi Li, Aimin Guo, Bin Liao, Jun Zhang

引用次数: 0

A soluble garlic polysaccharide supplement alleviates fatigue in mice 可溶性大蒜多糖补充剂能缓解小鼠的疲劳。

IF 6.3 1区农林科学

NPJ Science of Food Pub Date : 2024-11-21 DOI: 10.1038/s41538-024-00340-4

Tianyi Li, Chanyuan Xie, Zhenyang Tian, Ran Chai, Yuan Ren, Jiaxin Miao, Wentao Xu, Shimin Chang, Changhui Zhao

{"title":"A soluble garlic polysaccharide supplement alleviates fatigue in mice","authors":"Tianyi Li, Chanyuan Xie, Zhenyang Tian, Ran Chai, Yuan Ren, Jiaxin Miao, Wentao Xu, Shimin Chang, Changhui Zhao","doi":"10.1038/s41538-024-00340-4","DOIUrl":"10.1038/s41538-024-00340-4","url":null,"abstract":"Garlic polysaccharide (GP) is an inulin-type fructan with potent antioxidant activity, whereas its health-promoting functions are not well explored. In the current study, we established a fatigue model by forcing mice to swim in a water tank for at least one hour every day. We measured changes in body weight, exhaustive swimming time, and biochemical indices related to fatigue in weight-bearing swimming mice fed low (1.25 g/kg-BW) and high doses (2.5 g/kg-BW) of GP by daily gavage for 7 weeks. The soluble GP was extracted from industrial garlic wastes using a patented method. The results indicate that GP improved symptoms by increasing the duration of exhaustive swimming, restoring blood biochemical markers (BUN and BLA), and increasing liver and muscle glycogen reserves in fatigued mice. GP also increased antioxidant enzyme activity (SOD, GSH-Px, and CAT) and restored ATPase activity by activating the AMPK/PGC-1α pathway. Additionally, GP modified the gut microbiota by increasing potentially beneficial bacteria and decreasing harmful bacteria. The increase in Bacteroidota and the decrease in Firmicutes phyla regulate the metabolism of short-chain fatty acids in the gut. In conclusion, GP may be effective in alleviating exercise-induced fatigue through multiple mechanisms and can be developed into health anti-fatigue supplements.","PeriodicalId":19367,"journal":{"name":"NPJ Science of Food","volume":" ","pages":"1-10"},"PeriodicalIF":6.3,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41538-024-00340-4.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142687735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Akkermansia muciniphila ONE effectively ameliorates dextran sulfate sodium (DSS)-induced ulcerative colitis in mice Akkermansia muciniphila ONE 能有效改善硫酸右旋糖酐钠（DSS）诱导的小鼠溃疡性结肠炎

IF 6.3 1区农林科学

NPJ Science of Food Pub Date : 2024-11-19 DOI: 10.1038/s41538-024-00339-x

Zhang Hongyan, Pan Yue, Ying Jiang, Mengling Chen, Ma Xin, Xueping Yu, Dayong Ren, Bin Jiang

{"title":"Akkermansia muciniphila ONE effectively ameliorates dextran sulfate sodium (DSS)-induced ulcerative colitis in mice","authors":"Zhang Hongyan, Pan Yue, Ying Jiang, Mengling Chen, Ma Xin, Xueping Yu, Dayong Ren, Bin Jiang","doi":"10.1038/s41538-024-00339-x","DOIUrl":"10.1038/s41538-024-00339-x","url":null,"abstract":"Akermansia muciniphila shows promise as a next-generation probiotic, however, its beneficial regulatory effects on mice ulcerative colitis (UC) has not been extensively investigated. We used an Akkermansia muciniphila strain (AKK ONE) isolated from healthy human feces to study its effect on DSS-induced colitis in mice. Our results demonstrate that AKK ONE supplementation significantly improves food intake, weight, colon length, disease activity index (DAI) score, organ index, and tissue damage of colitis mice. AKK ONE notably improved intestinal barrier integrity by significantly enhancing expression of occludin and claudin-1. Additionally, AKK ONE reduced inflammation by down-regulating IL-1β, IL-6, and TNF-α, and up-regulating IL-10. In addition to reducing excessive inflammation, AKK ONE also increased the abundance of Akkermansia and decreased the abundance of Bacteroides. Furthermore, the AKK ONE intervention markedly increased SCFAs in cecal contents. AKK ONE may be a potential therapeutic agent for improving UC, based on the findings of this study.","PeriodicalId":19367,"journal":{"name":"NPJ Science of Food","volume":" ","pages":"1-11"},"PeriodicalIF":6.3,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41538-024-00339-x.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142672782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0