NPJ Science of Food最新文献

The physiological characteristics and applications of sialic acid.

IF 6.3 1区农林科学

NPJ Science of Food Pub Date : 2025-02-26 DOI: 10.1038/s41538-025-00390-2

Botao Wang, Tianmeng Zhang, Sheng Tang, Cuiping Liu, Chen Wang, Junying Bai

引用次数: 0

Cultivation of bovine lipid chunks on Aloe vera scaffolds.

IF 6.3 1区农林科学

NPJ Science of Food Pub Date : 2025-02-25 DOI: 10.1038/s41538-025-00391-1

Gilad Gome, Benyamin Chak, Shadi Tawil, Itai Rotem, Ivana Ribarski-Chorev, Jonathan Giron, Oded Shoseyov, Sharon Schlesinger

引用次数: 0

Preventive, ameliorative, and therapeutic effects of steamed mature silkworms on metabolic disorders caused by loss of apolipoprotein E.

IF 6.3 1区农林科学

NPJ Science of Food Pub Date : 2025-02-25 DOI: 10.1038/s41538-025-00392-0

Minh Anh Hoang Nguyen, Thanh Thi Tam Nguyen, Yoo Hee Kim, Young Ho Koh

{"title":"Preventive, ameliorative, and therapeutic effects of steamed mature silkworms on metabolic disorders caused by loss of apolipoprotein E.","authors":"Minh Anh Hoang Nguyen, Thanh Thi Tam Nguyen, Yoo Hee Kim, Young Ho Koh","doi":"10.1038/s41538-025-00392-0","DOIUrl":"10.1038/s41538-025-00392-0","url":null,"abstract":"Metabolic disorders encompass various dysregulations, such as dyslipidemia, hypertension, central obesity, atherogenic hyperlipidemia, and insulin resistance. Dyslipidemia refers to elevated levels of total cholesterol, low-density lipoprotein cholesterol, and triglycerides, along with decreased high-density lipoprotein cholesterol levels in the blood. Dyslipidemia is closely associated with hypertension, which is one of the important risk factors for cardiovascular disease.In this study, an apolipoprotein E-deficient (apoE-/-) mouse model was utilized to investigate whether supplementation with steamed mature silkworm, known as HongJam, might ameliorate and have therapeutic effects on metabolic disorders and behavioral abnormalities observed in apoE-/- mice. The Golden Silk HongJam-supplemented feed-consuming (GSf)-apoE-/- mice showed recovery from the reduced spatial memory, social memory, and postural control ability observed in the normal feed-consuming (Nf)-apoE-/- mice. They also exhibited similar blood pressure to those in the normal feed-consuming C57BL/6J control (Nf-Con) group. Additionally, the significantly reduced activities of glutathione-S-transferase, superoxide dismutase, acetylcholinesterase, and mitochondrial complexes I-IV in the Nf-apoE-/- group were restored in all GSf-apoE-/- groups. Furthermore, the amount of ATP in all GSf-apoE-/- mice was similar to or higher than that in the Nf-Con group.Taken together, GS HongJam supplementation may have preventive, ameliorative, and therapeutic effects on the symptoms of metabolic disorders caused by the loss of ApoE.","PeriodicalId":19367,"journal":{"name":"NPJ Science of Food","volume":"9 1","pages":"27"},"PeriodicalIF":6.3,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11862253/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143502946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultrasonicated Atlantic herring side streams as source of multifunctional bioactive and bioavailable peptides. 超声处理的大西洋鲱鱼侧流是多功能生物活性肽和生物可用肽的来源。

IF 6.3 1区农林科学

NPJ Science of Food Pub Date : 2025-02-22 DOI: 10.1038/s41538-025-00388-w

Gilda Aiello, Janna Cropotova, Kristine Kvangarsnes, Lorenza d'Adduzio, Melissa Fanzaga, Carlotta Bollati, Giovanna Boschin, Gabriella Roda, Carmen Lammi

{"title":"Ultrasonicated Atlantic herring side streams as source of multifunctional bioactive and bioavailable peptides.","authors":"Gilda Aiello, Janna Cropotova, Kristine Kvangarsnes, Lorenza d'Adduzio, Melissa Fanzaga, Carlotta Bollati, Giovanna Boschin, Gabriella Roda, Carmen Lammi","doi":"10.1038/s41538-025-00388-w","DOIUrl":"10.1038/s41538-025-00388-w","url":null,"abstract":"This study demonstrates the effectiveness of ultrasonication, as a pre-treatment technology, coupled to enzymatic hydrolysis of herring side streams, yielding multifunctional peptide mixtures with antioxidant, hypotensive (ACE inhibitory activity), and hypoglycemic (DPP-IV inhibitory and GLP-1 enhancer activity) properties. The ultrasound pre-treatment modulates the biological activity of the hydrolysates, enhancing certain bioactive properties (antioxidant, ACE inhibitory, and GLP-1 enhancer activities, respectively) while reducing others (DPP-IV inhibitory activity). The study also highlights the importance of simulating gastrointestinal digestion and using Caco-2 cells to assess the bioaccessibility, intestinal bioavailability, and metabolic resistance of herring peptides. These findings support the use of ultrasonication and enzymatic hydrolysis in obtaining multifunctional bioactive peptide mixture for the prevention of metabolic syndrome. Results clearly suggest that this approach represent sustainable solutions in food science and technology, since it allowed us to obtain a bioactive mixture of peptides starting from fish by-products pre-treated with green methodologies.","PeriodicalId":19367,"journal":{"name":"NPJ Science of Food","volume":"9 1","pages":"25"},"PeriodicalIF":6.3,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11847024/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143476780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Amylase/trypsin-inhibitor content and inhibitory activity of German common wheat landraces and modern varieties do not differ.

IF 6.3 1区农林科学

NPJ Science of Food Pub Date : 2025-02-20 DOI: 10.1038/s41538-025-00385-z

Nora Jahn, Sabrina Geisslitz, Ulla Konradl, Klaus Fleissner, Katharina A Scherf

引用次数: 0

Microalgae-enriched (bio)inks for 3D bioprinting of cultured seafood.

IF 6.3 1区农林科学

NPJ Science of Food Pub Date : 2025-02-12 DOI: 10.1038/s41538-025-00386-y

Diana M C Marques, Madalena Jabouille, Afonso Gusmão, Marco Leite, Paola Sanjuan-Alberte, Frederico Castelo Ferreira

{"title":"Microalgae-enriched (bio)inks for 3D bioprinting of cultured seafood.","authors":"Diana M C Marques, Madalena Jabouille, Afonso Gusmão, Marco Leite, Paola Sanjuan-Alberte, Frederico Castelo Ferreira","doi":"10.1038/s41538-025-00386-y","DOIUrl":"10.1038/s41538-025-00386-y","url":null,"abstract":"Cultured seafood offers a sustainable alternative to traditional seafood by eliminating the need for animal sacrifice and reducing environmental impacts. 3D bioprinting enables precise manufacturing of these products by combining animal cells with plant-based materials. This study introduces novel (bio)inks: (i) κ-CAM bioinks (κ-carrageenan, alginate, and methylcellulose) compatible with seabass cells; and (ii) mFAT inks, plant-based fat inks containing microalgae for enhanced organoleptic properties. κ-CAM bioinks revealed Young's modulus between 14.62 and 25.70 kPa values, suitable for cultured seafood products. Both κ-CAM and mFAT formulations presented adequate printability (Pr~1). Dicentrarchus labrax Embryonic Cells, encapsulated in κ-CAM bioinks, maintained viabilities >76.14% for up to 15 days. A preliminary assessment confirmed that specific microalgae can enhance the sea-like smell and flavor of the mFAT ink, and a 3D-printed calamari was fabricated to showcase its potential in the manufacturing of complex structures. Finally, hybrid structures combining both types of (bio)inks were also developed.","PeriodicalId":19367,"journal":{"name":"NPJ Science of Food","volume":"9 1","pages":"23"},"PeriodicalIF":6.3,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11821890/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143408403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Black raspberry supplementation on overweight and Helicobacter pylori infected mild dementia patients a pilot study.

IF 6.3 1区农林科学

NPJ Science of Food Pub Date : 2025-02-12 DOI: 10.1038/s41538-024-00356-w

Yohanes Tandoro, Hui-Fang Chiu, Chei-Ling Tan, Ming-Hong Hsieh, Yi-Wen Huang, Jianhua Yu, Li-Shu Wang, Chi-Ho Chan, Chin-Kun Wang

{"title":"Black raspberry supplementation on overweight and Helicobacter pylori infected mild dementia patients a pilot study.","authors":"Yohanes Tandoro, Hui-Fang Chiu, Chei-Ling Tan, Ming-Hong Hsieh, Yi-Wen Huang, Jianhua Yu, Li-Shu Wang, Chi-Ho Chan, Chin-Kun Wang","doi":"10.1038/s41538-024-00356-w","DOIUrl":"10.1038/s41538-024-00356-w","url":null,"abstract":"Alzheimer's disease (AD) is the most common form of dementia. H. pylori infection and overweight have been implicated in AD via the gut-brain axis (GBA). This study aimed to determine whether supplementation of BRBs has a meaningful effect on H. pylori infection, overweight, and AD development in a clinical trial setting. We conducted a randomized placebo-controlled clinical trial in patients with mild clinical dementia who also had H. pylori infection and were overweight. The study was conducted over 10 weeks, consisting of an 8-week intervention period (25 g powder of black raspberries, BRBs, or placebo twice daily, morning and evening) and a 2-week follow-up. The primary outcomes were changes in Clinical Dementia Rating (CDR), Urea Breath Test (UBT), and Body Mass Index (BMI). Consumption of BRBs improved cognitive functions (p < 0.00001), compared to the placebo group (p > 0.05). Besides, BRBs ingestion decreased H. pylori infection and BMI (p < 0.00001 and p < 0.05 respectively) while the placebo group stayed statistically the same (p = 0.98 and p = 0.25 respectively). BRBs significantly decreased inflammatory markers, improved oxidative index, and adiponectin (p < 0.05) compared to the placebo group, while adenosine monophosphate-activated protein kinase (AMPK) and leptin did not significantly change. BRBs modulated the abundance of several fecal probiotics, particularly, Akkermansia muciniphila. Our results provided that BRBs suppressed H. pylori infection, decreased BMI, and rebalanced the gut microbiome, which could improve cognitive functions in mild dementia patients. Longer and larger randomized clinical trials of BRB interventions targeting H. pylori infection, overweight, or mild dementia are warranted to confirm the results from this pilot trial. Trial Registration: ClinicalTrials.gov identifier: NCT05680532.","PeriodicalId":19367,"journal":{"name":"NPJ Science of Food","volume":"9 1","pages":"9"},"PeriodicalIF":6.3,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11821819/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143409659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The bsh1 gene of Lactobacillus plantarum AR113 ameliorates liver injury in colitis mice.

IF 6.3 1区农林科学

NPJ Science of Food Pub Date : 2025-02-11 DOI: 10.1038/s41538-025-00373-3

Junlin Shao, Yongjun Xia, Guangqiang Wang, Zhiqiang Xiong, Yijin Yang, Xin Song, Yu Wang, Lianzhong Ai

引用次数: 0

A perspective on the regulation of cultivated meat in the European Union.

IF 6.3 1区农林科学

NPJ Science of Food Pub Date : 2025-02-08 DOI: 10.1038/s41538-025-00384-0

Alessandro Monaco

引用次数: 0

Evaluate the stability of synthesized allicin and its reactivity with endogenous compounds in garlic.

IF 6.3 1区农林科学

NPJ Science of Food Pub Date : 2025-02-06 DOI: 10.1038/s41538-025-00374-2

Shanshan Zhou, Xiaoying Yan, Xuguang Qiao, Zhichang Qiu, Weihe Zhu, Xiaoming Lu, Zhenjia Zheng, Bin Zhang

{"title":"Evaluate the stability of synthesized allicin and its reactivity with endogenous compounds in garlic.","authors":"Shanshan Zhou, Xiaoying Yan, Xuguang Qiao, Zhichang Qiu, Weihe Zhu, Xiaoming Lu, Zhenjia Zheng, Bin Zhang","doi":"10.1038/s41538-025-00374-2","DOIUrl":"10.1038/s41538-025-00374-2","url":null,"abstract":"The study aimed to prepare allicin in large quantities and evaluate the effects of different conditions and endogenous substances (polyphenols and free amino acids) in garlic on its stability. The optimized synthesis conditions of allicin (DADS:HAc = 2:9, H2O2:DADS = 2:1.6, reacted for 6.5 h) were established based on response surface design. Allicin with 92.57% purity was obtained by high-speed counter-current chromatography. The results of allicin degradation experiment indicated that the degradation rate of allicin accelerated with the increases of initial concentration and temperature, the degradation process of allicin was good fit with two first-order kinetics (R2 > 0.97). The stability of allicin was higher in pH 2-5.8 than in pH 8-9. Apigenin, myricetin, and quercetin combined with peroxidase enhanced the stability of allicin. Cysteine, arginine, and histidine could react with allicin. These findings provide insights for optimizing for allicin storage and food processing applications.","PeriodicalId":19367,"journal":{"name":"NPJ Science of Food","volume":"9 1","pages":"18"},"PeriodicalIF":6.3,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11802734/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143365141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0