NPJ Science of Food最新文献_第10页

Prebiotic inulin ameliorates SARS-CoV-2 infection in hamsters by modulating the gut microbiome 益生菌菊粉通过调节肠道微生物组改善仓鼠的 SARS-CoV-2 感染情况

IF 6.4 1区农林科学

NPJ Science of Food Pub Date : 2024-03-14 DOI: 10.1038/s41538-024-00248-z

Isaiah Song, Jiayue Yang, Misa Saito, Tenagy Hartanto, Yasunori Nakayama, Takeshi Ichinohe, Shinji Fukuda

{"title":"Prebiotic inulin ameliorates SARS-CoV-2 infection in hamsters by modulating the gut microbiome","authors":"Isaiah Song, Jiayue Yang, Misa Saito, Tenagy Hartanto, Yasunori Nakayama, Takeshi Ichinohe, Shinji Fukuda","doi":"10.1038/s41538-024-00248-z","DOIUrl":"10.1038/s41538-024-00248-z","url":null,"abstract":"Current treatment options for COVID-19 are limited, with many antivirals and immunomodulators restricted to the most severe cases and preventative care limited to vaccination. As the SARS-CoV-2 virus and its increasing variants threaten to become a permanent fixture of our lives, this new reality necessitates the development of cost-effective and accessible treatment options for COVID-19. Studies have shown that there are correlations between the gut microbiome and severity of COVID-19, especially with regards to production of physiologically beneficial short-chain fatty acids (SCFAs) by gut microbes. In this study, we used a Syrian hamster model to study how dietary consumption of the prebiotic inulin affected morbidity and mortality resulting from SARS-CoV-2 infection. After two weeks of observation, we discovered that inulin supplementation attenuated morbid weight loss and increased survival rate in hamster subjects. An analysis of microbiome community structure showed significant alterations in 15 genera. Notably, there were also small increases in fecal DCA and a significant increase in serum DCA, perhaps highlighting a role for this secondary bile acid in conferring protection against SARS-CoV-2. In light of these results, inulin and other prebiotics are promising targets for future investigation as preventative treatment options for COVID-19.","PeriodicalId":19367,"journal":{"name":"NPJ Science of Food","volume":" ","pages":"1-9"},"PeriodicalIF":6.4,"publicationDate":"2024-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41538-024-00248-z.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140123819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantifying the potential renal acid load of edible mushrooms 量化食用菌潜在的肾酸负荷

IF 6.4 1区农林科学

NPJ Science of Food Pub Date : 2024-03-12 DOI: 10.1038/s41538-024-00259-w

Maximilian Andreas Storz

引用次数: 0

Bio-economic potential of ethno-entomophagy and its therapeutics in India 印度人种食道及其疗法的生物经济潜力。

IF 6.4 1区农林科学

NPJ Science of Food Pub Date : 2024-03-09 DOI: 10.1038/s41538-024-00260-3

Wahengbam Deepanita Devi, Rajkumari Bonysana, Kabrambam Dasanta Singh, Arunkumar Singh Koijam, Pulok Kumar Mukherjee, Yallappa Rajashekar

{"title":"Bio-economic potential of ethno-entomophagy and its therapeutics in India","authors":"Wahengbam Deepanita Devi, Rajkumari Bonysana, Kabrambam Dasanta Singh, Arunkumar Singh Koijam, Pulok Kumar Mukherjee, Yallappa Rajashekar","doi":"10.1038/s41538-024-00260-3","DOIUrl":"10.1038/s41538-024-00260-3","url":null,"abstract":"Insects are the largest group of arthropods with the highest faunal diversity of over a million species. Apart from many other roles in the environment, the aspect of several insects being used for human consumption (entomophagy) and as traditional medicine (entomotherapy) by different communities of the world holds special significance for countering global food crisis. The enormous insect resources contribute a reasonable share in improving the livelihoods of many entomophagy practicing communities. Considering this significance, the present review emphasizes the bio-economic potential of insect resources. An overview of entomophagy practices in India; benefits towards the environment, humans and animals; insect species used in entomophagy along with therapeutic importance, nutritional, physical, chemical, and microbiological hazards; farming and mass production technologies; legal status and socio-economic implications in Indian scenario have been presented. Traditionally tested and accepted therapeutic use of edible insects have been reported to cure various disease conditions and calls for scientific exploration and validation to rediscover promising medical products of modern medicine. Edible insects as an alternative food need to be popularized in India with a new policy or regulation to harvest and sell insect-derived food products with proper safe consumption demonstrations. Considering the facts that insects reproduce in large numbers at a faster rate, require less land, water and other resources for farming, and economically and ecologically sustainable harvesting can be done in a short time, insect farming can offer revenue and rural job opportunities in developing countries, especially in India. Therefore, the traditional use of insects as food and medicine has tremendous potential to enhance the economy and living standards.","PeriodicalId":19367,"journal":{"name":"NPJ Science of Food","volume":" ","pages":"1-11"},"PeriodicalIF":6.4,"publicationDate":"2024-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41538-024-00260-3.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140068614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tracing the origin of Argentine Malbec wines by sensometrics 通过感官计量学追溯阿根廷马尔贝克葡萄酒的起源。

IF 6.4 1区农林科学

NPJ Science of Food Pub Date : 2024-02-21 DOI: 10.1038/s41538-024-00252-3

Roy Urvieta, Hildegarde Heymann, Annegret Cantu, Aníbal Catania, Fernando Buscema, Rubén Bottini, Ariel Fontana

{"title":"Tracing the origin of Argentine Malbec wines by sensometrics","authors":"Roy Urvieta, Hildegarde Heymann, Annegret Cantu, Aníbal Catania, Fernando Buscema, Rubén Bottini, Ariel Fontana","doi":"10.1038/s41538-024-00252-3","DOIUrl":"10.1038/s41538-024-00252-3","url":null,"abstract":"The study of terroir, increasingly popular in scientific circles, remains a challenging field, particularly in terms of sensory analysis. This paper summarizes our own contribution to the field—an approach for tracing the typicity of wines by sensometrics, using the Malbec variety as a case study. This large-scale research fingerprinted 81 wines from 29 parcels from highly contrasting environments (varying climate, elevation, and soils), produced under standardized conditions in three consecutive vintages. Wines were evaluated through descriptive sensory analysis (DA) by a trained panel, and sensory descriptors were associated with different size geographic scales (zones, departments, and Geographic Indications (GIs)). The application of different sensometric tools allowed us to describe the typicity of wines and discriminate each region, proposing a novel methodology for the comprehensive evaluation of terroir from a sensory viewpoint. The vintage effect was very strong at the departmental and GI level, with aroma, taste and mouthfeel descriptors varying annually. However, certain origin descriptors remained consistent, providing insight into the typicity of Malbec. Considering the extension of the experimental study performed, this methodology provides a proof of concept for understanding both terroir and vintage effects from a sensorial perspective, offering wine producers and consumers a clear message backed by scientific evidence.","PeriodicalId":19367,"journal":{"name":"NPJ Science of Food","volume":" ","pages":"1-11"},"PeriodicalIF":6.4,"publicationDate":"2024-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41538-024-00252-3.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139913130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Stretchable zein-coated alginate fiber for aligning muscle cells to artificially produce cultivated meat 可拉伸的藻酸盐纤维，用于排列肌肉细胞以人工生产培养肉

IF 6.4 1区农林科学

NPJ Science of Food Pub Date : 2024-02-19 DOI: 10.1038/s41538-024-00257-y

Dayi Jeong, Goo Jang, Woo Kyung Jung, Yong Ho Park, Hojae Bae

引用次数: 0

Author Correction: Emerging challenges and opportunities in innovating food science technology and engineering education 作者更正：食品科学、技术和工程教育创新面临的新挑战和新机遇。

IF 6.4 1区农林科学

NPJ Science of Food Pub Date : 2024-02-13 DOI: 10.1038/s41538-024-00256-z

I. S. Saguy, C. L. M. Silva, E. Cohen

引用次数: 0

TrkB phosphorylation in serum extracellular vesicles correlates with cognitive function enhanced by ergothioneine in humans 血清细胞外囊泡中的 TrkB 磷酸化与麦角硫因增强人体认知功能有关

IF 6.4 1区农林科学

NPJ Science of Food Pub Date : 2024-02-06 DOI: 10.1038/s41538-024-00250-5

Takahiro Ishimoto, Reiya Yamashita, Ruri Matsumoto, Satoshi Matsumoto, Yusuke Matsuo, Shunsuke Nakao, Yusuke Masuo, Makoto Suzuki, Yukio Kato

{"title":"TrkB phosphorylation in serum extracellular vesicles correlates with cognitive function enhanced by ergothioneine in humans","authors":"Takahiro Ishimoto, Reiya Yamashita, Ruri Matsumoto, Satoshi Matsumoto, Yusuke Matsuo, Shunsuke Nakao, Yusuke Masuo, Makoto Suzuki, Yukio Kato","doi":"10.1038/s41538-024-00250-5","DOIUrl":"10.1038/s41538-024-00250-5","url":null,"abstract":"Oral administration of the food-derived antioxidant amino acid ergothioneine (ERGO) results in its efficient distribution in the brain and enhances cognitive function. However, effect of ERGO deficiency on cognitive impairment and the underlying mechanisms remain unknown. We revealed that cognitive function and hippocampal neurogenesis were lower in mice fed an ERGO-free diet than in those fed the control diet. Furthermore, ERGO supplementation to achieve the control diet ERGO levels reversed these effects and restored ERGO concentrations in the plasma and hippocampus. The ERGO-induced recovery of cognitive function and hippocampal neurogenesis was blocked by inhibiting the neurotrophic factor receptor tropomyosin receptor kinase B (TrkB), with a concomitant reduction in hippocampal phosphorylated TrkB, suggesting the involvement of TrkB in these events in mice. Phosphorylated TrkB was also detected in extracellular vesicles (EVs) derived from serum of volunteers who had been orally administered placebo or ERGO-containing tablets. Importantly, the ratio of serum EV-derived phosphorylated TrkB was significantly higher in the ERGO-treated group than in the placebo-treated group and was positively correlated with both serum ERGO concentrations and several cognitive domain scores from Cognitrax. Altogether, TrkB phosphorylation is involved in ERGO-induced cognitive enhancement in mice, and TrkB phosphorylation levels in serum EVs may quantitatively represent ERGO-induced cognitive enhancement in humans.","PeriodicalId":19367,"journal":{"name":"NPJ Science of Food","volume":" ","pages":"1-13"},"PeriodicalIF":6.4,"publicationDate":"2024-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41538-024-00250-5.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139695539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unacceptable use of substandard metrics in policy decisions which mandate large reductions in animal-source foods 在政策决定中使用低于标准的衡量标准，强制要求大量减少动物源性食品，这是不可接受的

IF 6.4 1区农林科学

NPJ Science of Food Pub Date : 2024-02-05 DOI: 10.1038/s41538-024-00249-y

Alice V. Stanton

{"title":"Unacceptable use of substandard metrics in policy decisions which mandate large reductions in animal-source foods","authors":"Alice V. Stanton","doi":"10.1038/s41538-024-00249-y","DOIUrl":"10.1038/s41538-024-00249-y","url":null,"abstract":"Many recent very influential reports, including those from the Global Burden of Disease (GBD) Risk Factor Collaborators, the EAT-Lancet Commission on Food, Planet, Health, and the Lancet Countdown on Health and Climate Change, have recommended dramatic reductions or total exclusion of animal-source foods, particularly ruminant products (red meat and dairy), from the human diet. They strongly suggest that these dietary shifts will not only benefit planetary health but also human health. However, as detailed in this perspective, there are grounds for considerable concern in regard to the quality and transparency of the input data, the validity of the assumptions, and the appropriateness of the statistical modelling, used in the calculation of the global health estimates, which underpin the claimed human health benefits. The lessor bioavailability of protein and key micronutrients from plant-source foods versus animal-source foods was not adequately recognised nor addressed in any of these reports. Furthermore, assessments of bias and certainty were either limited or absent. Despite many of these errors and limitations being publically acknowledged by the GBD and the EAT-Lancet authors, no corrections have been applied to the published papers. As a consequence, these reports continue to erroneously influence food policy decisions and international dietary guidelines, such as the World Wildlife Fund’s Livewell Diet, and the Nordic Nutrition Recommendations 2023.","PeriodicalId":19367,"journal":{"name":"NPJ Science of Food","volume":" ","pages":"1-8"},"PeriodicalIF":6.4,"publicationDate":"2024-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41538-024-00249-y.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139683031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of gelatin type and concentration on the preparation and properties of freeze-dried fish oil powders 明胶类型和浓度对冻干鱼油粉的制备和特性的影响

IF 6.4 1区农林科学

NPJ Science of Food Pub Date : 2024-02-03 DOI: 10.1038/s41538-024-00251-4

Mengyang Yang, Jiawei Peng, Cuiping Shi, Ye Zi, Yulu Zheng, Xichang Wang, Jian Zhong

{"title":"Effects of gelatin type and concentration on the preparation and properties of freeze-dried fish oil powders","authors":"Mengyang Yang, Jiawei Peng, Cuiping Shi, Ye Zi, Yulu Zheng, Xichang Wang, Jian Zhong","doi":"10.1038/s41538-024-00251-4","DOIUrl":"10.1038/s41538-024-00251-4","url":null,"abstract":"The effects of gelatin type (porcine skin gelatin, PSG; bovine skin gelatin, BSG; fish gelatin, FG; or cold-water fish skin gelatin, CFG) and concentration on the preparation and properties of fish oil powders were investigated in this work. The oil powders were prepared using the combination method of gelatin-sodium hexametaphosphate complex coacervation with starch sodium octenyl succinate (SSOS)-aided freeze-drying. Compared with the other gelatins, CFG—with an unobvious isoelectric point, a lower molecular weight, more hydrogen bonds, and longer gel formation time—could not form complex coacervates, which are necessary to prepare oil powders. For oil powders obtained from the other gelatins, gelatin type and concentration did not have obvious effects on microscale morphologies; they did, however, have significant effects on physicochemical properties. The highest peroxide values of the oil powders were mainly dependent on the gelatins, expressed in the following manner: PSG (153 ± 5 – 168 ± 3 meq/Kg oil) < BSG (176 ± 5 – 188 ± 1 meq/Kg oil) < FG (196 ± 11 – 201 ± 22 meq/Kg oil). Acidic and neutral pH could not dissolve the complex coacervates. However, the oil powders could be quickly dissolved to form emulsion droplets in the gastric phase, and that SSOS increased coacervate stability and promoted oil digestion during the in vitro gastrointestinal process. In sum, this study contributes fundamental information to understanding the development of fish oil solid encapsulation preparations.","PeriodicalId":19367,"journal":{"name":"NPJ Science of Food","volume":" ","pages":"1-11"},"PeriodicalIF":6.4,"publicationDate":"2024-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41538-024-00251-4.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139662392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Metabolic changes in response to varying whole-grain wheat and rye intake 不同全麦和黑麦摄入量引起的代谢变化。

IF 6.4 1区农林科学

NPJ Science of Food Pub Date : 2024-01-30 DOI: 10.1038/s41538-024-00247-0

Ville M. Koistinen, Sumanto Haldar, Marjo Tuomainen, Marko Lehtonen, Anton Klåvus, John Draper, Amanda Lloyd, Manfred Beckmann, Wendy Bal, Alastair B. Ross, Kirsten Brandt, Lee Fawcett, Chris Seal, Kati Hanhineva

{"title":"Metabolic changes in response to varying whole-grain wheat and rye intake","authors":"Ville M. Koistinen, Sumanto Haldar, Marjo Tuomainen, Marko Lehtonen, Anton Klåvus, John Draper, Amanda Lloyd, Manfred Beckmann, Wendy Bal, Alastair B. Ross, Kirsten Brandt, Lee Fawcett, Chris Seal, Kati Hanhineva","doi":"10.1038/s41538-024-00247-0","DOIUrl":"10.1038/s41538-024-00247-0","url":null,"abstract":"Epidemiological studies have shown associations between whole-grain intake and lowered disease risk. A sufficient level of whole-grain intake to reach the health benefits has not been established, and there is limited knowledge about the impact of whole-grain intake on metabolite levels. In this clinical intervention study, we aimed to identify plasma and urine metabolites associated with two different intake levels of whole-grain wheat and rye and to correlate them with clinical plasma biomarkers. Healthy volunteers (N = 68) were divided into two groups receiving either whole-grain wheat or whole-grain rye in two four-week interventions with 48 and 96 g/d of whole grains consumed. The metabolomics of the plasma samples was performed with UPLC–QTOF-MS. Plasma alkylresorcinols were quantified with GC-MS and plasma and urinary mammalian lignans with HPLC-ECD. The high-dose intervention impacted the metabolite profile, including microbial metabolites, more in the rye-enriched diet compared with wheat. Among the increased metabolites were alkylresorcinol glucuronides, sinapyl alcohol, and pipecolic acid betaine, while the decreased metabolites included acylcarnitines and ether lipids. Plasma alkylresorcinols, urinary enterolactone, and total mammalian lignans reflected the study diets in a dose-dependent manner. Several key metabolites linked with whole-grain consumption and gut microbial metabolism increased in a linear manner between the two interventions. The results reveal that an increase in whole-grain intake, particularly rye, is strongly reflected in the metabolite profile, is correlated with clinical variables, and suggests that a diet rich in whole grains promotes the growth and/or metabolism of microbes producing potentially beneficial microbial metabolites.","PeriodicalId":19367,"journal":{"name":"NPJ Science of Food","volume":" ","pages":"1-14"},"PeriodicalIF":6.4,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41538-024-00247-0.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139642677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0