Neuroreport最新文献

{"title":"Changes in topological properties of brain structural covariance networks and alertness in temporal lobe epilepsy with and without focal to bilateral tonic-clonic seizures.","authors":"Chuanyong Qu, Zexiang Chen, Shujun Su, Cuimi Luo, Ligen Fan, Yuting Sun, Jinou Zheng","doi":"10.1097/WNR.0000000000002164","DOIUrl":"10.1097/WNR.0000000000002164","url":null,"abstract":"<p><p>This study investigated brain structural covariance network (SCN) topological changes and alertness in temporal lobe epilepsy (TLE) with and without focal to bilateral tonic-clonic seizures (FBTCS). Seventy-eight subjects, including 32 TLE patients with FBTCS (TLE-FBTCS), 46 TLE patients without FBTCS (TLE-FS), and 42 healthy controls (HCs), underwent the Attention Network Test to assess alertness and volumetric MRI scans. SCNs were constructed and analyzed using graph theory. Results showed that TLE-FS patients had lower total cerebral volume than HCs, and the lowest volume was observed in the TLE-FBTCS group. Compared to HCs and TLE-FBTCS patients, TLE-FS patients exhibited increased small-worldness, normalized clustering coefficient, global efficiency, and modularity, but decreased normalized characteristic shortest path length and assortativity. Specific brain regions, such as the hippocampus, thalamus, and superior temporal sulcus, showed changes in nodal clustering coefficients and efficiency in TLE-FS patients. Further analysis revealed decreased intrinsic/phasic alertness in TLE-FBTCS patients. Correlation analysis indicated that SCN topological properties were associated with alertness in TLE-FS patients but not in TLE-FBTCS patients. These findings suggest that TLE-FS and TLE-FBTCS patients show different changes in SCN integration and segregation, with TLE-FS alertness linked to SCN topological properties, providing insights into TLE's neuropathological mechanisms.</p>","PeriodicalId":19213,"journal":{"name":"Neuroreport","volume":" ","pages":"421-434"},"PeriodicalIF":1.6,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144045989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multimodal neuroimaging alterations and host genetic associations in patients with rhegmatogenous retinal detachment: a transcriptomic-neuroimaging study.","authors":"Yu Ji, Yi-Chong Duan, Lin Zhou, Hua Chai, Hao-Yu Yuan, Zhuo-Er Dong, Li-Li Yao, Xiao-Rong Wu","doi":"10.1097/WNR.0000000000002161","DOIUrl":"10.1097/WNR.0000000000002161","url":null,"abstract":"<p><p>Previous neuroimaging studies have identified functional and structural changes in the gray matter of rhegmatogenous retinal detachment (RRD) patients, yet the genetic mechanisms behind these alterations remain unclear. We employed multimodal imaging to investigate gray matter alterations in RRD patients. A transcriptome-neuroimaging spatial correlation analysis, integrating gene expression data from the Allen Human Brain Atlas, identified genes linked to functional stability changes. We followed this with gene enrichment, protein-protein interaction (PPI) network mapping, and expression profiling. RRD patients showed distinct, sustained dynamic balance within the default mode network functionally, and a significant reduction in gray matter volume in the visual network region structurally, compared with healthy controls. Transcriptome-neuroimaging correlation analysis revealed a spatial link between functional and structural changes and the expression profiles of 165 genes involved in membrane organization, neurodegeneration, phagocytosis, and calcium signaling. These genes form a highly interconnected PPI network, centered around key hub genes. Tissue- and cell-specific expression analysis highlighted a distinct gene expression pattern, especially in D1 receptor-positive cells in the caudate-putamen. Our findings indicate alterations in gray matter function and structure in RRD patients, particularly in regions involved in visual and cognitive processing. Transcriptomic neuroimaging analysis reveals that these changes are linked to the expression of multiple genes, shedding light on potential genetic mechanisms underlying RRD-associated gray matter modifications and offering new insights for treatment and prognosis.</p>","PeriodicalId":19213,"journal":{"name":"Neuroreport","volume":" ","pages":"389-401"},"PeriodicalIF":1.6,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143972645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stimulus-preceding negativity and P3 reflecting relative amounts of attention allocation between primary and secondary tasks.","authors":"Yasunori Kotani, Atsushi Horai, Yoshimi Ohgami, Lucian Gheorghe","doi":"10.1097/WNR.0000000000002165","DOIUrl":"10.1097/WNR.0000000000002165","url":null,"abstract":"<p><strong>Objective: </strong>This study examined event-related potentials, particularly P3, in two attention states: a 'focused attention state', wherein attention was fully allocated to a primary task, and a 'poor attention state', wherein attention was disrupted by a secondary task, to elucidate attention allocation mechanisms during multitasking.</p><p><strong>Methods: </strong>P3 was recorded under two conditions. The focus condition (focused attention state) involved only the primary task. The split-attention condition (poor attention state) included both primary and secondary tasks. Stimulus-preceding negativity (SPN) evoked by the secondary task was also recorded in the split-attention condition.</p><p><strong>Results: </strong>P3 amplitude was significantly higher in the focus condition than in the split-attention condition. Importantly, a novel finding revealed a negative correlation between SPN amplitude for the secondary task and P3 amplitude for the primary task, suggesting a trade-off in attention allocation. Source analysis of the P3 revealed that regions associated with attention shifting and inhibitory control were active during the focus condition. In contrast, regions linked to impaired cognitive-sensory integration and increased impulsivity were prominent during the split-attention condition.</p><p><strong>Conclusion: </strong>This study highlights a new finding: SPN and P3 amplitudes are interrelated, reflecting relative attention allocation between tasks. In poor attention states, impaired attentional shifting and inhibitory control led to reduced P3 amplitude for the primary task and heightened SPN activity for the secondary task.</p>","PeriodicalId":19213,"journal":{"name":"Neuroreport","volume":" ","pages":"412-420"},"PeriodicalIF":1.6,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12043257/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144012786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of deep brain stimulation for lateral hypothalamic area on memory decline and hippocampal neurofilaments expression dysfunctions in aged rats.","authors":"Somaya Saad, Ahmed F Abouelnaga, Marwa Abass, Walaa Obydah, Nedaa A Kiwan, Omar Abd-Alhakem Ammar, Osama A Abulseoud, Abdelaziz M Hussein","doi":"10.1097/WNR.0000000000002162","DOIUrl":"10.1097/WNR.0000000000002162","url":null,"abstract":"<p><strong>Objective: </strong>Studying the effect of deep brain stimulation (DBS) in the lateral hypothalamic area (LHA) in young and aging rats regarding memory changes, hippocampal neuronal dystrophy, and neurofilament expression.</p><p><strong>Methods: </strong>Thirty-six male Sprague-Dawley rats were divided into two main groups: adult young ( n  = 18, 8 weeks old) and aged ( n  = 18, 24 months old). Each main group was further subdivided into three equal subgroups ( n  = 6) including control, sham, and DBS. DBS of LHA was conducted using high-frequency electric currents (130 Hz) for 1.5 h with 5-min breaks every 30 min for five consecutive days. Assessment of working memory was done using passive avoidance test (PAT). Then, the brain was dissected and hippocampal neuronal dystrophic damage was assessed as well as immunohistochemical examination of neurofilaments (NF68, NF200) expression.</p><p><strong>Results: </strong>Aging rats had progressive hippocampal neuronal degeneration and downregulation of heavy and light chain neurofilaments, that was associated with progressive decline in working memory. Nevertheless, activation of DBS in the LHA enhanced memory function as it increased latency to entry in PAT ( P  < 0.001) compared to old normal and sham groups. Dystrophic damage score significantly decreased with DBS ( P  < 0.001) in the hippocampal CA1, CA3, and dentate gyrus regions. Moreover, DBS upregulated hippocampal NF68, NF200 expression ( P  < 0.001) in both young and old rats. We also found a significant positive correlation between working memory and NFs expression and a negative correlation between dystrophic damage score and NFs expression.</p><p><strong>Conclusions: </strong>DBS in the LHA may have a neuroprotective effect in aging rats as it enhanced the working memory and decreased hippocampal neuronal dystrophy. This protective effect may be caused by the upregulation of neurofilaments.</p>","PeriodicalId":19213,"journal":{"name":"Neuroreport","volume":" ","pages":"402-411"},"PeriodicalIF":1.6,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143973439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alterations in static and dynamic functional network connectivity in chronic low back pain: a resting-state network functional connectivity and machine learning study.","authors":"Hao Liu, Xin Wan","doi":"10.1097/WNR.0000000000002158","DOIUrl":"https://doi.org/10.1097/WNR.0000000000002158","url":null,"abstract":"<p><p>Low back pain (LBP) is a prevalent pain condition whose persistence can lead to changes in the brain regions responsible for sensory, cognitive, attentional, and emotional processing. Previous neuroimaging studies have identified various structural and functional abnormalities in patients with LBP; however, how the static and dynamic large-scale functional network connectivity (FNC) of the brain is affected in these patients remains unclear. Forty-one patients with chronic low back pain (cLBP) and 42 healthy controls underwent resting-state functional MRI scanning. The independent component analysis method was employed to extract the resting-state networks. Subsequently, we calculate and compare between groups for static intra- and inter-network functional connectivity. In addition, we investigated the differences between dynamic functional network connectivity and dynamic temporal metrics between cLBP patients and healthy controls. Finally, we tried to distinguish cLBP patients from healthy controls by support vector machine method. The results showed that significant reductions in functional connectivity within the network were found within the DMN,DAN, and ECN in cLBP patients. Significant between-group differences were also found in static FNC and in each state of dynamic FNC. In addition, in terms of dynamic temporal metrics, fraction time and mean dwell time were significantly altered in cLBP patients. In conclusion, our study suggests the existence of static and dynamic large-scale brain network alterations in patients with cLBP. The findings provide insights into the neural mechanisms underlying various brain function abnormalities and altered pain experiences in patients with cLBP.</p>","PeriodicalId":19213,"journal":{"name":"Neuroreport","volume":"36 7","pages":"364-377"},"PeriodicalIF":1.6,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144014809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dancers' resistance to vertigo cannot be explained by a generalized suppression of vestibular signaling.","authors":"Karina Moïn-Darbari, Daniel Paromov, Benoit-Antoine Bacon, Maxime Maheu, François Champoux","doi":"10.1097/WNR.0000000000002160","DOIUrl":"https://doi.org/10.1097/WNR.0000000000002160","url":null,"abstract":"<p><p>From a vestibular perspective, it is remarkable that dancers are often performing challenging tasks such as pirouettes, and yet manage to do so without falling. Some have suggested that dancers' resistance to vertigo may be explained by a generalized suppression of vestibular signaling. Here, we aimed to test this hypothesis by examining the impact of galvanic vestibular stimulation (GVS) on postural control in dancers. A total of 38 participants were recruited for this study and were divided into two groups: 19 dancers and 19 healthy controls. Postural control was assessed at baseline and during GVS. As expected, dancers exhibited better postural control, as assessed by a decrease in sway area, when compared to the control group in the baseline condition. However, contrary to expectations, dancers did not differ from controls during GVS. This confirms that dancers' resistance to vertigo cannot be explained by a generalized suppression of vestibular signaling. Rather, dancers may have developed a more accurate body representation due to top-down modulation of subcortical neuronal networks and may only be able to modify vestibular input during active movement.</p>","PeriodicalId":19213,"journal":{"name":"Neuroreport","volume":"36 7","pages":"378-381"},"PeriodicalIF":1.6,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144006202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation between basal ganglia nuclei and cortical gray matter volume changes in different motor subtypes of Parkinson's disease.","authors":"Jun Lu, Xinyue Huangfu, Yumei Zhang, Yan Nan, Minhai Wang, Weilan Zhang, Chengwei Wang","doi":"10.1097/WNR.0000000000002155","DOIUrl":"https://doi.org/10.1097/WNR.0000000000002155","url":null,"abstract":"<p><p>Explore the correlation between basal ganglia nuclei and cortical gray matter volume changes in tremor-dominant and postural instability-gait difficulty (PIGD) Parkinson's disease subtypes for Parkinson's disease diagnosis and individualized treatment. High-resolution 3D-T1WI MRI data from 35 tremor-dominant and 30 PIGD patientsand 35 healthy controls were analyzed. Voxel-based morphometry identified gray matter volume differences. Automated basal ganglia segmentation quantified subcortical volumes, followed by multivariate analysis of covariance and Spearman correlation analyses. Compared with healthy control, patients with PIGD exhibited severe gray matter loss (P < 0.0001), while tremor-dominant showed nonsignificant reductions. Subcortically, different basal ganglia volumes were atrophied in the tremor-dominant and PIGD groups compared with the healthy control (P < 0.05). PIGD demonstrated greater left putamen atrophy than tremor-dominant (P < 0.05). Spearman correlation analysis revealed that the volume of the right globus pallidus was positively correlated with that of the left medial and lateral cingulate gyrus in patients with tremor-dominant (r = 0.35, P = 0.04); and between the left globus pallidus volume and the right superior temporal gyrus volume in patients with PIGD (r = 0.47, P = 0.01). Compared with the tremor-dominant subtype, the PIGD subtype exhibits more severe GM atrophy, with different basal ganglia volume changes across subtypes. These altered anatomical features and the correlation between degeneration of the basal ganglia region and cortical gray matter changes may provide insights into the differential functional changes in patients with different motor subtypes and help to elucidate the underlying pathologic mechanisms.</p>","PeriodicalId":19213,"journal":{"name":"Neuroreport","volume":"36 7","pages":"342-349"},"PeriodicalIF":1.6,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143972826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long noncoding RNA MALAT1 promotes angiogenesis through the caveolin-1/VEGF pathway after cerebral ischemic injury.","authors":"Yao Lin, Qiongyi Pang, Yuanxi Shi, Xiang Chen, Fengxia Tu","doi":"10.1097/WNR.0000000000002157","DOIUrl":"https://doi.org/10.1097/WNR.0000000000002157","url":null,"abstract":"<p><p>The long noncoding RNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) might protect against cerebral ischemic injury. This study explored MALAT1's function in ischemic stroke and whether it acts through the caveolin-1/vascular endothelial growth factor (VEGF) pathway. A mouse model of middle cerebral artery occlusion/reperfusion (MCAO/R) and a human brain microvascular endothelial cell (HBMEC) model of oxygen-glucose deprivation/reoxygenation (OGD/R) were established. Lentiviral vectors for MALAT1 knockdown, caveolin-1 knockdown, and MALAT1 overexpression were used for gene regulation studies. Neurological deficits, endothelial cell proliferation, cell apoptosis, cell viability, in vitro angiogenesis, cell migration, and the expression of related gene and protein were evaluated using the Zea Longa five-point scale, VEGF receptor 2/CD34 double immunofluorescence, TdT-mediated dUTP nick end labeling staining, cell counting kit-8 assay, tube formation assay, transwell assay, quantitative real time PCR, and western blot. In mouse MCAO/R model and HBMEC OGD/R model, the expression levels of MALAT1, caveolin-1, and VEGF were significantly upregulated compared to the control group. In vivo, downregulation of MALAT1 expression exacerbated cerebral ischemic injury as manifested by severe neurological deficits, larger infarct volume, increased apoptosis, decreased numbers of VEGF receptor 2+/CD34+ endothelial progenitor cells, increased cell apoptosis, and the downregulation of caveolin-1 and VEGF. Conversely, overexpression of MALAT1 partially reversed the inhibition of cell migration and tubule formation by caveolin-1 gene downregulation, and restored in the expression of caveolin-1 and VEGF. MALAT1 promotes angiogenesis after cerebral ischemic injury, likely in part via the caveolin-1/VEGF pathway. Thus, MALAT1 may serve as a potential therapeutic target for ischemic stroke.</p>","PeriodicalId":19213,"journal":{"name":"Neuroreport","volume":"36 7","pages":"350-363"},"PeriodicalIF":1.6,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144021596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Code conflict in an event file task is reflected by aperiodic neural activity.","authors":"Jimin Yan, Lorenza Colzato, Bernhard Hommel","doi":"10.1097/WNR.0000000000002156","DOIUrl":"https://doi.org/10.1097/WNR.0000000000002156","url":null,"abstract":"<p><p>We investigated the relationship between aperiodic electroencephalography (EEG) activity and code conflict, hypothesizing that the former might serve as an indicator of the latter. We analyzed EEG and behavioral outcomes of a sample performing the event file task, which assesses code conflict in co-occurring or temporally overlapping stimulus and response features. To quantify aperiodic activity, we employed the fitting oscillations & one-over-f algorithm. The behavioral results revealed a typical partial-repetition cost effect, indicating that performance is impaired if the stimulus repeats while the response alternates, or vice versa. This suggests that the previously combined shape and response were stored in an event file and retrieved when any one of these components was repeated. Notably, this effect was also evident in the aperiodic exponent, which was lower for partial repetitions than for full repetitions or alternations, implying increased cortical noise, a higher excitatory E/I ratio, and noisier decision-making processes. The scalp distribution of this effect aligns with its sensorimotor characteristics. Thus, we interpret these findings as promising preliminary evidence that the aperiodic exponent may serve as a valuable neural marker of code conflict.</p>","PeriodicalId":19213,"journal":{"name":"Neuroreport","volume":"36 7","pages":"337-341"},"PeriodicalIF":1.6,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144021594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hydrogen sulfide improves poststroke depression-induced inflammation in microglial cells by enhancing endoplasmic reticulum autophagy and inhibiting the cGAS-STING pathway.","authors":"Bang Luo, Yao Xie, Wending Kuang, Yuzheng Wang, Gang Chen, Yang Zhang, Mei Yuan","doi":"10.1097/WNR.0000000000002152","DOIUrl":"10.1097/WNR.0000000000002152","url":null,"abstract":"<p><p>Poststroke depression (PSD) affects approximately one-third of stroke survivors, contributing to poor outcomes and elevated mortality. This study aimed to investigate the therapeutic effects of hydrogen sulfide (H2S), administered as sodium hydrosulfide (NaHS), on PSD-induced inflammation, with a focus on the modulation of the cyclic GMP-AMP synthase (cGAS)-stimulator of interferon gene (STING) pathway and the enhancement of endoplasmic reticulum (ER) autophagy in microglial cells. An in-vivo rat model was established to evaluate the effects of NaHS on depression-like behaviors and inflammation. Mechanistic studies were conducted in vitro using BV2 microglia subjected to oxygen-glucose deprivation (OGD) and corticosterone. Key inflammatory markers, cGAS-STING pathway activity, and ER-autophagy-related proteins were analyzed using quantitative reverse transcription PCR, Western blotting, ELISA, transmission electron microscopy, and immunofluorescence staining. Depression-like behaviors in rats were assessed using the forced swimming and tail suspension tests. H2S treatment ameliorated depression-like symptoms, mitigated hippocampal damage, and reduced pro-inflammatory markers, including NOD-like receptor protein 3, interleukin-1β (IL-1β), and IL-18 by inhibiting the cGAS-STING pathway. Furthermore, H2S significantly upregulated autophagy-related proteins (LC3, Beclin-1, and FAM134B) and autophagic vesicles, indicating enhanced ER autophagy. Notably, silencing FAM134B reversed the inhibitory effects of H2S on the cGAS-STING pathway, underscoring the pivotal role of ER autophagy in H2S-mediated neuroprotection. These findings demonstrate that H2S mitigates PSD-induced microglial inflammation and depression-like behaviors by inhibiting the cGAS-STING pathway and promoting ER autophagy, suggesting its potential as a therapeutic strategy for PSD. Further investigation into H2S and autophagy-related pathways could reveal novel therapeutic avenues for neuroinflammatory conditions.</p>","PeriodicalId":19213,"journal":{"name":"Neuroreport","volume":"36 6","pages":"314-326"},"PeriodicalIF":1.6,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143772406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}