Neurosurgical Review最新文献

{"title":"Bobble-head doll syndrome and Suprasellar Arachnoid cyst: A rare experience and systematic literature review.","authors":"Sivaraman Kumarasamy, Rajeev Sharma, Satish Kumar Verma, Pankaj Kumar Singh, Deepak Kumar Gupta, Ashish Suri, Shashank Sharad Kale","doi":"10.1007/s10143-025-03770-0","DOIUrl":"https://doi.org/10.1007/s10143-025-03770-0","url":null,"abstract":"<p><strong>Background: </strong>Bobble-head doll syndrome (BHDS) is a rare movement disorder characterized by continuous or periodic head movements. The head nodding or bobbing occurs either forward and backward (yes-yes) or side-to-side movement (no-no) direction at a 2-3 Hz frequency. It is due to lesions in and around the third ventricle, causing pressure on periventricular neuronal structures (thalami). The most common lesions are suprasellar arachnoid cysts. We intend to analyze the clinical presentation, imaging findings, treatment options, and surgical outcome of BHDS in suprasellar arachnoid cysts.</p><p><strong>Methods: </strong>We retrospectively reviewed our database for BHDS in suprasellar arachnoid cysts surgically treated between 2016-2023. Patient records were reviewed with special attention to patient demographics, presentation, imaging findings, site and extent, surgery performed, complications, and outcomes.</p><p><strong>Results: </strong>A total of 5 patients with a mean age of 6.7 years were included in the study. Abnormal head movements were the most common presenting complaint. The mean duration of symptoms was 2.9 ± 2 years. All patients underwent cyst fenestration (endoscopic or microscopic assisted). Approaches used: craniotomy and microscopic-assisted cyst fenestration in 1 patient (20%) and endoscopic-assisted cyst fenestration in 4 patients (80%). One patient had partial resolution of symptoms at 6 weeks' follow-up. The remaining four patients (80%) had complete resolution of symptoms at 3-month follow-up.</p><p><strong>Conclusion: </strong>BHDS is a rare movement disorder caused by lesions in and around the third ventricle. Neuroimaging can help in diagnosing this lesion. The most common clinical presentations are involuntary head movements related to the dilatation of the third ventricle and obstructive hydrocephalus. It is a surgical condition with a favourable outcome. Various treatment options are described in the literature. Endoscopic fenestration is the optimal and most commonly performed treatment option. The excellent outcome in BHDS with suprasellar arachnoid cysts can be achieved using endoscopic fenestration.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"645"},"PeriodicalIF":2.5,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145075938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: Comparative overall survival analysis of chordomas of the base of the skull from the Surveillance, Epidemiology, and End Results (SEER) program between 2000 and 2020.","authors":"Kevin E Agner, Michael C Larkins","doi":"10.1007/s10143-025-03819-0","DOIUrl":"10.1007/s10143-025-03819-0","url":null,"abstract":"","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"642"},"PeriodicalIF":2.5,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12441062/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145070082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Middle meningeal artery embolization in patients treated with Japanese Kampo Goreisan for recurrent chronic subdural hematoma: a prospective cohort comparative study.","authors":"Yosuke Akamatsu, Kohei Chida, Kenya Miyoshi, Daigo Kojima, Shota Tsutsui, Koji Yoshida, Toshinari Misaki, Takahiro Koji, Shunrou Fujiwara, Hiroshi Kashimura, Kuniaki Ogasawara","doi":"10.1007/s10143-025-03821-6","DOIUrl":"10.1007/s10143-025-03821-6","url":null,"abstract":"<p><p>Adjuvant middle meningeal artery embolization (MMAE) after burr-hole drainage for chronic subdural hematoma (CSDH) has emerged as a promising strategy. However, in Japan, MMAE is not covered by national health insurance; thus, it has been reserved for patients with recurrent CSDHs after burr-hole drainage. Goreisan has been reported to lower the incidence of recurrent CSDHs. Hence, we investigated the synergistic effect of MMAE and Goreisan in patients with recurrent CSDH. We prospectively included patients with recurrent CSDHs who received Goreisan after burr-hole drainage and separated them into groups based on whether MMAE was performed (group B + G + MMAE) or not (group B + G). Out of 605 patients who underwent burr-hole drainage for CSDHs, groups B + G and B + G + MMAE comprised 20 and 34 consecutive patients, respectively. Patient characteristics, such as age, sex, antithrombotic medications, history of blood coagulopathy disorders, and the modified Rankin scale (mRS) scores before symptom onset, did not differ between the two groups. No significant differences in the incidence of re-recurrent CSDHs (5% and 5.8%, in groups B + G and B + G + MMAE, p > 0.05, respectively) and favorable functional outcome (mRS score ≤ 2) at 3-month retreatment (90% and 76.5% in groups B + G and B + G + MMAE, p > 0.05, respectively) were found in the two groups 3 months post-retreatment. A positive effect of MMAE in preventing the re-recurrence of CSDHs in patients treated with Goreisan for recurrent CSDHs was not observed.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"643"},"PeriodicalIF":2.5,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145070045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling gut microbiome divergence in sellar-parasellar masses and brain tumors: A link beyond the skull.","authors":"Aycan Gundogdu, O Ufuk Nalbantoglu, Meric Ulgen, M Aydin Sav, Gazanfer Ekinci, Fahrettin Kelestimur, Uğur Türe","doi":"10.1007/s10143-025-03788-4","DOIUrl":"10.1007/s10143-025-03788-4","url":null,"abstract":"<p><p>The gut microbiome is increasingly linked to systemic health and central nervous system disorders, including brain tumors. This study investigated gut microbiome composition and metabolic profiles in patients with sellar-parasellar tumors (SPTs), other brain tumor types (OBTs) and healthy controls (HCs) to identify microbial and metabolic biomarkers for brain tumor phenotypes. A cross-sectional study involving 56 participants (17 SPTs, 11 OBTs, 28 HCs) was conducted. Gut microbiota composition was analyzed with 16 S rRNA sequencing, and metabolic activity was inferred via metagenome-scale metabolic models. Multivariable regression and machine learning were used to evaluate microbial and metabolic differences across groups. Taxonomic and metabolic analyses revealed distinct profiles across these groups. The result showed that HCs exhibited higher levels of Lachnospira and Comamonadaceae, while tumor patients had an over-representation of Bacilli. OBT patients showed elevated metabolic exchange scores (MES) for amino acids (D-alanine, L-glutamic acid), carbohydrates (mucin-type O-glycans, alpha-lactose), and lipids (stearic acid, choline), most likely reflecting tumor-associated metabolic demands. Conversely, SPT patients had profiles closer to HCs, with lower MES and reduced systemic disruption. Key taxa such as Akkermansia, Faecalibacterium, and Lachnospira demonstrated tumor-specific adaptive metabolic outputs, emphasizing functional microbial contributions over purely taxonomic roles. These findings highlight the role of gut microbiota in brain tumor progression through altered metabolic pathways, suggesting potential biomarkers and therapeutic targets for neuro- oncology. The study integrates genome-scale metabolic modeling with 16 S profiling to show that functional metabolic divergence can exist even when taxonomic differences are subtle, revealing overlooked biomarkers of the gut-brain axis in neuro-oncology.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"641"},"PeriodicalIF":2.5,"publicationDate":"2025-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145054791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: Supracerebellar-supratrochlear and supracerebellar-infratrochlear triangles as gateways to the posterolateral midbrain and ambient cistern: descriptive and quantitative analysis of microsurgical anatomy.","authors":"Sahin Hanalioglu, Kivanc Yangi, Muhammet Enes Gurses, Hilal Akdemir Aktas, Egemen Gok, Osman Tunc, Michael T Lawton, Mark C Preul","doi":"10.1007/s10143-025-03791-9","DOIUrl":"https://doi.org/10.1007/s10143-025-03791-9","url":null,"abstract":"","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"640"},"PeriodicalIF":2.5,"publicationDate":"2025-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145054822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A meta-analytic insight into predictors and consequences of intra-procedural rupture in unruptured intracranial aneurysms.","authors":"Mustafa Ismail, Norito Kinjo, Imad Samman Tahhan, Nooruldeen H Ali Al-Khafaji, Rania H Al-Taie, Alejandro M Spiotta","doi":"10.1007/s10143-025-03810-9","DOIUrl":"10.1007/s10143-025-03810-9","url":null,"abstract":"<p><p>Intra-procedural rupture (IPR) is a rare yet devastating complication during endovascular treatment (EVT) of unruptured intracranial aneurysms. This study aimed to systematically assess the predictors, procedural risk factors, and clinical outcomes of IPR through meta-analytic synthesis. Following PRISMA 2020 guidelines, a systematic search of PubMed and Scopus was conducted through May 2025. Eleven retrospective studies, including 11,081 unruptured aneurysms, were analyzed. Risk factors, procedural characteristics, and clinical outcomes were evaluated, and pooled proportions and odds ratios were calculated using random-effects models. The crude estimated incidence of IPR among unruptured aneurysms across all studies was approximately 6.4%. Advanced age (≥ 60 years; 99.8%), female sex (63.3%), and hypertension (44.1%) were prevalent among IPR cases. Irregular aneurysm morphology (82.9%) and anterior communicating artery (ACom) location (22.3%) emerged as significant anatomical predictors. The simple coiling technique was associated with higher IPR rates (23.4% vs. 15.7%, p < 0.001), whereas no IPR events were reported with flow diverters. Only 22.3% of patients had favorable long-term outcomes. IPR in EVT of unruptured aneurysms is rare but severe, primarily affecting elderly hypertensive females with irregular ACom aneurysms. Simple coiling techniques heighten risk, while flow diverters show promise as safer alternatives. Targeted strategies are needed to prevent this critical complication.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"638"},"PeriodicalIF":2.5,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145040829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A systematic review of clinical features of intradiploic epidermoid cysts and strategies for patient management.","authors":"Kishore Balasubramanian, Abdurrahman Kharbat, Ammar Haider, Deep Parikh, Jaime Cuellar Iii, Francisco Call-Orellana, Paolo Palmisciano, Othman Bin-Alamer, Sibi Rajendran, Christopher S Graffeo, Jeffrey A Zuccato, Ian F Dunn","doi":"10.1007/s10143-025-03798-2","DOIUrl":"10.1007/s10143-025-03798-2","url":null,"abstract":"<p><p>Intradiploic epidermoid cysts (IECs) are rare cystic calvarial lesions. Due to their rarity, there is a clinical need to aggregate the collective experience reported in the literature to characterize typical clinical features, clinical predictors of patient outcomes, and management strategies used for this entity. Following PRI SMA guidelines, 127 patients from 94 studies (77 case reports, 17 case series) were included with individual patient data. Clinical data on demographics, clinical presentation, imaging features, management approaches, and outcomes were characterized, and predictors of outcome were evaluated. The cohort had a median age of 44 years (range = 18-81). Common presenting clinical features included headache (50%) and a palpable mass (48%), with half reporting antecedent head trauma. Lesions most frequently involved the occipital (28%), frontal (26%), and parietal bones (15%), with 13% localizing to multiple bones of the calvarium. Surgical resection was performed in all but one case, achieving a gross total resection (GTR) in 92% and complete cyst capsule removal in 87%. The rate of recurrence was significantly lower in those who received a GTR versus a subtotal resection (4% vs. 57%, p < 0.001) and in cases where the capsule was completely versus incompletely removed (2% vs. 66%, p < 0.001). IECs should be suspected in patients presenting with headaches or palpable skull masses with osteolytic non-enhancing and diffusion-restricting T2 hyperintense calvarial lesions. Complete surgical excision with total cyst capsule removal is the goal for IEC management. Close long-term monitoring remains essential, particularly in lesions that have been subtotally resected.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"639"},"PeriodicalIF":2.5,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145040826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of intraoperative flow cytometry on intracranial tumor surgery : a scoping review.","authors":"Eleni Romeo, Georgios Markopoulos, Spyridon Voulgaris, George Vartholomatos, George A Alexiou","doi":"10.1007/s10143-025-03789-3","DOIUrl":"10.1007/s10143-025-03789-3","url":null,"abstract":"<p><strong>Background: </strong>The aim of this review is to present the role of intraoperative flow cytometry (IFC) in the intracranial tumor surgery. This scoping review aims to summarize current evidence on the intraoperative use of IFC in patients with intracranial tumors.</p><p><strong>Methods: </strong>A comprehensive literature search was conducted in the Medline, Cochrane and Scopus databases up to January 21, 2025. Data extraction was carried out following the use of preset inclusion and exclusion criteria.</p><p><strong>Results: </strong>A total of 14 studies were analyzed in this review, involving 1.043 patients with intracranial tumors to assess the utility of IFC in the rapid diagnosis of these tumors. The studies evaluated IFC for grading gliomas and meningiomas, distinguishing tumor margins, determining tumor prognosis, and its application in pediatric tumors, metastases, and primary central nervous system lymphomas. The most promising applications of IFC are in glioma and meningioma grading, as well as in identifying glioma margins. IFC appears to be a valuable intraoperative tool for intracranial tumor classification, providing rapid results within minutes.</p><p><strong>Conclusion: </strong>IFC shows potential as a real-time, intraoperative tool for brain tumor classification and surgical guidance. Nevertheless, studies in this field are limited, and further research with more robust data is needed to establish specific cut-off values that will enable reliable conclusions.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"637"},"PeriodicalIF":2.5,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145023877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of weight classes on feasibility, safety, and efficacy of awake craniotomy for brain lesions within eloquent areas.","authors":"Alexandre Gehanno, Alexandre Roux, Angela Elia, Luca Paun, Marco Demasi, Louis Mineo, Cédric Roussel, Cheick-Ahmed Komara, Xavier Schumacher, Benoit Hudelist, Alessandro Moiraghi, Bénédicte Trancart, Maïmiti Seneca, Agathe Guibert, Edouard Dezamis, Catherine Oppenheim, Fabrice Chrétien, Marc Zanello, Johan Pallud","doi":"10.1007/s10143-025-03779-5","DOIUrl":"10.1007/s10143-025-03779-5","url":null,"abstract":"<p><p>Awake craniotomy is the gold standard to achieve maximal safe resection of brain lesions located within eloquent areas. There are no established guidelines to assess patient's eligibility for awake craniotomy by weight class. This study assesses feasibility, safety, and efficacy of awake surgery by weight classes through an observational, retrospective, single-institution cohort analysis (2010-2024) of 526 awake craniotomies. Comparison between normal weight (n = 276, 18.5 ≤ Body Mass Index (BMI) < 25 kg/m²), underweight (n = 34, BMI < 18.5 kg/m²), overweight (n = 158, 25 ≤ BMI < 30 kg/m²), and obese patients (n = 58, BMI > 30 kg/m²) were analyzed. Differences in weight classes in patients undergoing awake craniotomy: (1) were associated with a higher rate of intraoperative hypertension in underweight (8.8%), overweight (8.2%) and obese (8.2%) compared to normal weight patients (1.8%, p = 0.010); (2) did not increase the duration of the procedure (p = 0.754) but was associated with more frequent late awakening (> 30 min) in underweight (23.5%) compared to overweight (10.8%), obese (6.9%), and normal weight patients (8.7%, p = 0.044); (3) did not increase the occurrence of intraoperative epileptic seizures (p = 0.2) or intraoperative insufficient cooperation (p = 0.790); (4) did not impact resection rates (p = 0.165) and tumor residue (p = 0.559); (5) did not significantly increase surgery-related complications (p = 0,217) or duration of hospital stay (p = 0.099); (6) did not worsen the 6-month KPS score (p = 0.599), seizure control (p = 0.987), and time to return to work (p = 0.653). Our findings suggest that awake craniotomy is safe and feasible both in underweight and overweight patients, including severely obese patients, compared to patients with a normal weight.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"636"},"PeriodicalIF":2.5,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145023828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intravenous thrombolysis before endovascular therapy for acute ischemic stroke due to tandem lesions: a systematic review and meta-analysis.","authors":"Aaron Rodriguez-Calienes, Martha I Vilca-Salas, Jason Z Gao, Jenny K Huynh, Arsh Manazir, Anish K Venkatesan, Yujing Lu, Venkat Uppalapti, Cristian Morán-Mariños, Mohamed Elfil, Amer M Malik, Dileep R Yavagal, Santiago Ortega-Gutierrez","doi":"10.1007/s10143-025-03786-6","DOIUrl":"10.1007/s10143-025-03786-6","url":null,"abstract":"<p><p>The role of intravenous thrombolysis (IVT) in patients with tandem lesions (TL) undergoing endovascular thrombectomy (EVT) for acute ischemic stroke (AIS) remains a subject of ongoing debate. The substantial clot burden and the potential need for periprocedural antiplatelet therapy during emergent carotid stenting (CAS) add to the complexity of treatment decisions. This study aims to systematically review and meta-analyze the literature to evaluate the comparative safety and efficacy of IVT plus EVT versus EVT alone in AIS patients with TL. A systematic search was conducted across four databases to identify studies comparing outcomes for patients with TL receiving IVT prior to EVT with those receiving EVT alone. Outcomes of interest included symptomatic intracranial hemorrhage (sICH), functional independence (90-day modified Rankin Scale 0-2), successful reperfusion (modified Thrombolysis in Cerebral Infarction 2b-3), and 90-day mortality. We performed a random-effects meta-analysis to calculate pooled odds ratios (OR) for each outcome and conducted a sensitivity analysis for patients who underwent emergent CAS. The analysis included 24 studies with a total of 3,294 patients: 1,860 (56.5%) received IVT plus EVT, and 1,434 (43.5%) received EVT alone. There was no significant increase in the risk of sICH between the IVT + EVT and EVT alone groups (IVT + EVT: 8.4% vs. EVT alone: 8.8%; OR = 0.90; 95%CI 0.67-1.21; I² = 5%). The sensitivity analysis showed no significant difference in sICH between patients treated with IVT before emergent CAS and those who received CAS alone (IVT + CAS: 10.6% vs. CAS alone: 10.9%; OR = 0.78; 95%CI 0.44-1.37; I² = 0%). Patients treated with IVT before EVT had significantly higher odds of functional independence (IVT + EVT: 52.6% vs. EVT alone: 44.1%; OR = 1.34; 95%CI 1.13-1.59; I² = 2.5%) and successful reperfusion (IVT + EVT: 83.3% vs. EVT alone: 79.8%; OR = 1.47; 95%CI 1.14-1.89; I² = 14%). Additionally, the IVT + EVT group had lower odds of 90-day mortality (IVT + EVT: 13.4% vs. EVT alone: 21.1%; OR = 0.61; 95%CI 0.47-0.78; I² = 0%). In conclusion, the current meta-analysis provides supporting evidence indicating that the combination of IVT and EVT does not increase the risk of sICH in patients with TL, even in the context of emergent CAS. Notably, IVT + EVT may offer potential benefits in achieving functional independence, successful reperfusion, and reducing mortality compared to EVT alone. However, randomized controlled trials are needed to validate these findings.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"634"},"PeriodicalIF":2.5,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12417230/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145015846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}