Neurosurgical Review最新文献

{"title":"Examination of variables linked to the recurrence of primary trigeminal neuralgia following percutaneous transluminal micro balloon compression.","authors":"Xiaoxuan Sun, Haitao Huang, Yanfeng Li, Fangkun Jing","doi":"10.1007/s10143-025-03651-6","DOIUrl":"https://doi.org/10.1007/s10143-025-03651-6","url":null,"abstract":"","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"510"},"PeriodicalIF":2.5,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144294152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Main complications of epilepsy surgery performed in a single center in Latin America.","authors":"Irving Fuentes-Calvo, Jimena Gonzalez-Salido, Fernando Sotelo-Díaz, Jimena Colado-Martinez, Irene Gómez-Oropeza, Betsy C Vázquez-Cruz, Fernando Vasquez-Lopez, Luis A Marin-Castañeda, Mario A Sebastián-Díaz, Sergio Moreno-Jiménez, Alfonso Arellano-Reynoso, Guillermo Axayacalt Gutiérrez-Aceves, Salvador Martínez-Medina, Santiago Philibert-Rosas, Oscar Isaac Vázquez-Hernández, Juan Carlos Vera-López, Nahomi M Herrera-Noguera, Fernando M Chavez-Hassan, Juana Villeda-Hernandez, Maximo Leon-Vazquez, Aurelio Jara-Prado, Adriana Ochoa-Morales, Jorge Guerrero-Camacho, Diego A Barrios-González, Mario A Alonso-Vanegas, Iris E Martínez-Juárez","doi":"10.1007/s10143-025-03665-0","DOIUrl":"10.1007/s10143-025-03665-0","url":null,"abstract":"<p><strong>Objective: </strong>Describe the main medical and neurological complications following epilepsy surgery at a tertiary care center in Latin America.</p><p><strong>Materials and methods: </strong>A retrospective study was conducted from 2006 to 2013 at the National Institute of Neurology and Neurosurgery in Mexico City. Patients aged over 18 years with drug-resistant epilepsy who underwent surgery and had a minimum follow-up of one year were included. Statistical analyses performed were Fisher's exact test, Pearson's Chi-square, and one-way ANOVA with Tukey post hoc for multiple comparisons.</p><p><strong>Results: </strong>Of 204 clinical records reviewed, 165 met inclusion criteria, and 95 (57.6%) underwent epilepsy surgery. Most patients (73.7%) had temporal lobectomy with amygdalohippocampectomy, followed by lesionectomy (9.5%), corpus callosotomy (15.8%), and one (0.6%) vagus nerve stimulator implantation. Minor medical complications occurred in 6.3% of patients, with extracranial infection (4.2%) and CSF fistula (2.1%) being the most common. Minor neurological complications were observed in 29.5%, including cranial nerve deficits (2.1%), intracranial hematoma (2.1%), and quadrantanopia (25.3%). One patient (1.1%) experienced a major complication (hemianopsia).</p><p><strong>Conclusion: </strong>This large LATAM cohort highlights the low complication rate of epilepsy surgery. Early referral of DRE patients demonstrated statistically significant favorable outcomes and fewer postoperative complications. Despite its demonstrated safety when performed by experienced specialists, its underutilization persists due to access barriers, even though untreated epilepsy poses significantly greater risks.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"509"},"PeriodicalIF":2.5,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12165962/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144294153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of carotid atherosclerotic plaque characteristics using optical coherence tomography.","authors":"Hao Feng, Xiaobing Li, Zequan Yu, Wei Liu","doi":"10.1007/s10143-025-03663-2","DOIUrl":"https://doi.org/10.1007/s10143-025-03663-2","url":null,"abstract":"<p><strong>Objective: </strong>This study focused on the characteristics of carotid atherosclerotic plaques using Optical Coherence Tomography (OCT) and compared the plaque features between elderly and young-to-middle-aged patients.</p><p><strong>Methods: </strong>Seventy patients with carotid atherosclerotic stenosis underwent carotid OCT examination and were included in the study. Their demographic and clinical data, such as age, gender, coexisting conditions (including hypertension, hyperlipidemia, stroke, and coronary heart disease), smoking and medication histories, and biochemical parameters (fasting blood glucose, triglycerides, total cholesterol, high-density lipoprotein, and low-density lipoprotein) were documented. Additionally, characteristics of the carotid plaques (such as plaque rupture, minimum lumen area, fiber cap thickness, thrombus proportion, fibrous plaque, macrophage infiltration, and calcified plaque) were recorded. Based on age, patients were categorized into an elderly group (> 60 years) and a young-to-middle-aged group (≤ 60 years). Furthermore, they were stratified into symptomatic and asymptomatic groups according to the manifestation of symptoms. Comparisons of the aforementioned indicators were conducted across these groups.</p><p><strong>Results: </strong>The elderly group had a higher proportion of plaque rupture than the young-to-middle-aged group (P < 0.05). Additionally, the symptomatic group showed a lower detection rate of fibrous plaque compared to the asymptomatic group (P < 0.05). Conversely, the detection rates of plaque rupture and macrophage infiltration were significantly higher in the symptomatic group (P < 0.05).</p><p><strong>Conclusion: </strong>OCT has evaluative value for the characteristics of carotid atherosclerotic stenosis plaques.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"507"},"PeriodicalIF":2.5,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144285795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DWI-based deep learning radiomics nomogram for predicting the impaired quality of life in patients with unruptured intracranial aneurysm developing new iatrogenic cerebral infarcts following stent placement: a multicenter cohort study.","authors":"Ruokun Chen, Yuzhao Lu, Zhongbin Tian, Junfan Chen, Wenbin Li, Chao Wang, Zhiwei Zhang, Xiaofei Huang, Cong Ding, Xianzhi Liu, Wenqiang Li","doi":"10.1007/s10143-025-03628-5","DOIUrl":"10.1007/s10143-025-03628-5","url":null,"abstract":"<p><p>This study developed a DWI-based radiomics nomogram to predict impaired health-related quality of life (HRQOL) in patients with unruptured intracranial aneurysms after stent placement, focusing on those who developed new iatrogenic cerebral infarct (NICI). Data from 522 patients across multiple hospitals were divided into a training cohort and two external validation cohorts. Radiomic and deep learning features from DWI-based infarct images were selected through super-resolution reconstruction. Impaired HRQOL was defined as a reduction in any of the five EQ-5D-3L domains. Three signatures (clinical, radiomic, and deep learning) were constructed, with a nomogram developed using multivariable logistic regression. Model performance was assessed using receiver operating characteristic analysis, calibration curves, and decision curve analysis. The clinical signature identified key predictors: NICI lesion count/volume, procedure time, diabetes, hypertension, ischemic stroke history, and multiple stents. The radiomic signature achieved optimal performance through super-resolution reconstruction, while GoogleNet showed the best classification performance among deep learning models. The integrated DLRN model achieved high predictive accuracy across all cohorts (AUCs: 0.960, 0.917, 0.936), outperforming individual signatures and traditional models. Calibration curves and decision curve analysis confirmed the DLRN model's reliability and clinical utility. The DLRN model integrating clinical, radiomic, and DTL features accurately predicted 1-year post-procedural HRQOL impairment, surpassing single-modality models and demonstrating clinical applicability for personalized treatment planning.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"508"},"PeriodicalIF":2.5,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144285796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unilateral approach to bilateral middle cerebral artery aneurysms: a large series and a proposed grading system to predict technical difficulties.","authors":"Servet Inci, Sacide Kalaycioglu","doi":"10.1007/s10143-025-03634-7","DOIUrl":"10.1007/s10143-025-03634-7","url":null,"abstract":"<p><p>This study includes the surgical treatment of 31 patients with bilateral MCA (bMCA) aneurysms using a unilateral approach and is the second largest series in the literature. The main aim of this study is to present a proposed grading system to preoperatively predict the difficulties in this approach. The clinical files, radiological studies, operation records, intraoperative video recordings, complications and outcomes of 31 patients were retrospectively reviewed. In the first part of this study (2001-2010), we operated on 22 patients with bMCA aneurysms and were able to clip the contralateral aneurysm via unilateral approach in only 12 cases (54.5%). Considering our experience from the surgery of these patients, we identified 5 parameters that reveal surgical difficulties. In the second part of the study (2011-2023), considering these 5 parameters, 20 patients were selected for unilateral approach and bilateral aneurysms could be clipped in 19 patients (95%). As a result, 26 of 31 patients (83.9%) were discharged with a favorable outcome (mRS 0-2, excellent-good). Intraoperative rupture occurred in one patient. Based on our experience, we developed a grading system with a total of 10 points by assigning points according to the degree of difficulty of each parameter and classified surgical difficulty as follows: 0-1 low difficulty, 2-3 moderate difficulty, 4-6 high difficulty and 7-10 very high difficulty. Patients with bMCA aneurysms can be operated via unilateral approach in experienced hands in properly selected cases. This grading system may help the neurosurgeon in this selection by preoperatively predicting intraoperative difficulties. This study is a completely retrospective file scan. This is not a clinical trial. Clinical trial number: not applicable.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"504"},"PeriodicalIF":2.5,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12162754/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The use of Bevacizumab in the treatment of brain arteriovenous malformations: a systematic review.","authors":"Asfand Baig Mirza, Feras Fayez, Marwan Al-Munaer, Ariadni Georgiannakis, Layla Burn, Karthik Ravi, Amisha Vastani, Christoforos Syrris, Jash Patel, Samir Matloob","doi":"10.1007/s10143-025-03667-y","DOIUrl":"10.1007/s10143-025-03667-y","url":null,"abstract":"<p><p>Brain arteriovenous malformations (bAVMs) are high-flow vascular anomalies associated with a significant risk of intracranial haemorrhage, particularly in young individuals. Standard treatments-including microsurgery, stereotactic radiosurgery (SRS), and endovascular embolization-are not feasible for all patients, especially those with high-grade or surgically inaccessible lesions. Bevacizumab, a monoclonal antibody targeting vascular endothelial growth factor (VEGF), has emerged as a potential medical therapy aimed at modulating angiogenesis and managing post-treatment complications. This systematic review was conducted according to PRISMA guidelines and registered with PROSPERO (CRD42024563735). A comprehensive search of PubMed, Embase, and Medline was performed up to March 2024, using terms related to Bevacizumab and brain AVMs. Studies were included if they involved adult patients with intracranial AVMs and were published in English. Two reviewers independently screened and extracted data, and quality was assessed using NIH tools.Twelve studies met inclusion criteria, comprising pilot trials, case series, and case reports. One study investigated Bevacizumab as a standalone treatment for inoperable bAVMs, demonstrating safety but no reduction in nidus volume. The remaining studies assessed Bevacizumab in the management of radiation-induced complications-including necrosis and steroid-resistant oedema-following SRS. Across these, Bevacizumab was consistently associated with clinical and radiological improvements and had a favourable safety profile, though most studies were limited by small sample sizes and lack of control groups. There is insufficient evidence to support Bevacizumab as a first-line treatment for bAVMs. However, early data suggest it may play a valuable adjunctive role in managing post-SRS complications. Future research should include larger, controlled studies with diverse patient populations, varied dosing regimens, and long-term follow-up to better define its therapeutic potential and positioning within the bAVM treatment paradigm.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"506"},"PeriodicalIF":2.5,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical characteristics and management of cerebral developmental venous anomalies accompanied with cavernous malformation.","authors":"Jiasheng Pei, Qizuan Chen, Huijian Zhang, Liangfeng Wei, Shousen Wang","doi":"10.1007/s10143-025-03652-5","DOIUrl":"10.1007/s10143-025-03652-5","url":null,"abstract":"<p><p>Developmental venous anomalies (DVAs) are common cerebral vascular anomalies that are frequently accompanied by cavernous malformations (CM), with mixed research on whether DVAs increase or decrease the risk of CM bleeding. This retrospective observational study aimed to investigate the clinical characteristics and management of DVAs accompanied by CMs. This study involved the clinical data of all patients with DVAs accompanied with CM from January 2013 to December 2023. A total of 14 patients aged 16-62 years (42.86 ± 14.56), were followed up for 10 to 150 months (53.57 ± 39.15). Twelve patients had a single CM, and two patients had multiple CMs. Nine patients did not experience bleeding, most patients showed no symptom aggravation throughout clinical observation or conservative treatment. Five patients with hemorrhage near the DVAs of the posterior cranial fossa experienced headache or focal neurological dysfunction. Two patients underwent surgery, and three obtained conservative treatment without new severe neurological dysfunction. Multiple de novo CMs formed after hemorrhage in two cases. Hemorrhage around the posterior fossa DVA may be an early signal of de novo CM.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"505"},"PeriodicalIF":2.5,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12162766/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A meta-analysis and systematic review: association of timing and muscle strength after nerve transfer in upper trunk palsy.","authors":"Samuel Nodal, Adham M Khalafallah, Bhavjeet S Sanghera, Mateo Garcia Barreto, Emily L Errante, Allan D Levi, Wilson Zachary Ray, S Shelby Burks","doi":"10.1007/s10143-025-03641-8","DOIUrl":"10.1007/s10143-025-03641-8","url":null,"abstract":"<p><p>A systematic review following PRISMA guidelines was conducted to address the PICO question: Does early (< 6 months) nerve transfer improve muscle strength outcomes when compared to late (≥ 6 months) nerve transfer for upper trunk palsy, as measured by the Medical Research Council (MRC) scale? The association between age and successful muscle function recovery was assessed as a secondary outcome. The quality of included studies was evaluated using the Methodological Index for Non-Randomized Studies (MINORS) tool. A total of 349 studies were screened, with 27 studies meeting criteria for systematic review, and 16 included in the meta-analysis. Most patients were young adult males who underwent a variety of different types of nerve transfers such as spinal accessory to suprascapular or triceps branch to axillary. Overall, 181 patients underwent nerve transfer within 6 months of injury, while 139 underwent nerve transfer after 6 months. Patients who underwent early nerve transfer had a 0.87 point higher postoperative MRC, compared to patients in the delayed period (p < 0.00001, n = 320), nearly a whole point difference in the MRC scale which is clinically significant and could make the difference between achieving functional muscle strength (MRC ≥ 3) or not. Additionally, patients who achieved functional postoperative muscle strength were 5.56 years younger than patients who did not (95% CI = [0.92, 10.20], n = 274). All included studies were of moderate quality according to MINORS, except one of poor quality. In conclusion, early nerve transfers for upper trunk palsy are associated with clinically and statistically significant improvements in muscle strength. When feasible, patients with persistent severe upper trunk palsy should undergo nerve transfer within 6 months post-injury.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"503"},"PeriodicalIF":2.5,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison between spinal fusion vs. nonoperative treatment for lumbar degenerative pathology: a systematic review and meta-analysis.","authors":"Khaled Moghib, Gergis Altalab, Arwa Jader, Thoria I Essa Ghanm, Mesan Hijazy, Dana Y Tarawneh, Ramish Hannat, Izere Salomon, Ahmed Ibrahim Edress, Muhannad Wael Abu Arafeh, Olivier Uwishema, Joshua Limantoro, Antonio Medina Luna, Ismail Bozkurt","doi":"10.1007/s10143-025-03671-2","DOIUrl":"10.1007/s10143-025-03671-2","url":null,"abstract":"<p><strong>Background: </strong>Lumbar fusion is widely used to treat chronic lumbar degenerative pathology; however, its effectiveness and safety compared with nonoperative management remain controversial.</p><p><strong>Objectives: </strong>This systematic review and meta-analysis aimed to evaluate and compare the effectiveness and safety of spinal fusion and conservative management in treating lumbar degenerative pathology.</p><p><strong>Method: </strong>A systematic review and meta-analysis were conducted following the PRISMA guidelines. The PubMed, Scopus, Cochrane Central, Web of Science, and Embase databases were searched in October 2024. Eligible studies included randomized controlled trials (RCTs) and observational studies reporting pain reduction and functional disability outcomes. The primary outcomes were changes in the Oswestry Disability Index (ODI) and Visual Analog Scale (VAS) scores for back and leg pain. Data were analyzed using a random-effects model in RevMan 5.4.1, with subgroup and sensitivity analyses performed to address heterogeneity.</p><p><strong>Results: </strong>Fourteen studies comprising 13 RCTs and one cohort study, involving 2,399 participants, were included. Spinal fusion showed significant improvements in ODI scores compared to conservative treatment (MD = -6.3; 95% CI [-12.02, -0.57]; p = 0.03), indicating reduced disability. VAS back pain scores also favored spinal fusion (MD = -3.02; 95% CI [-5, 1.04]; p = 0.003), with long-term outcomes showing consistent benefits (MD = -2.26; 95% CI [-3.16, 1.37]; p < 0.00001). However, spinal fusion did not significantly reduce leg pain compared to non-operative options (MD = -2.27; 95% CI [-8.37, 3.83]; p = 0.47).</p><p><strong>Conclusion: </strong>Spinal fusion offers statistically significant benefits in reducing disability and back pain compared with conservative treatments for lumbar degenerative pathology. However, it does not confer substantial advantages to leg pain and carries a high surgical risk. These findings emphasize the importance of individualized treatment selection based on patient characteristics and clinical indications.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"502"},"PeriodicalIF":2.5,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144266880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rapid ventricular pacing in cerebral aneurysm clipping: institutional workflow, systematic review, and single-arm meta-analysis.","authors":"Johannes Wach, Martin Vychopen, Ferdinand Weber, Felix Arlt, Erdem Güresir","doi":"10.1007/s10143-025-03668-x","DOIUrl":"10.1007/s10143-025-03668-x","url":null,"abstract":"<p><strong>Background: </strong>This study examines the safety and efficacy of rapid ventricular pacing for cerebral aneurysm clipping, focusing on arrhythmia, mortality, aneurysm obliteration, neurological deficits, and myocardial damage assessed via postoperative troponin T levels, through an institutional series, systematic review, and meta-analysis.</p><p><strong>Methods: </strong>Data were extracted from institutional database and published studies investigating the use of RVP in both ruptured and unruptured aneurysms. Outcomes analyzed included postoperative arrhythmia, mortality, complete obliteration of aneurysms, pacing cycles, mean arterial pressure (MAP) during pacing, pacing rates, and postoperative troponin T levels. Pooled event rates and proportions were calculated using a common effect model, and heterogeneity across studies was assessed using I² statistics.</p><p><strong>Results: </strong>In 15 institutional cases, RVP-assisted aneurysm clipping achieved stable neurological outcomes, no cardiac complications, and 94% aneurysm obliteration. Combined with literature (141 patients), pooled arrhythmia and mortality rates were 1% and 0%, respectively. Aneurysm obliteration was 92%, new neurological deficits 4%, and troponin T levels 37.7 ng/L. Mean pacing rate, cycles, and MAP were 187.4 bpm, 6.5, and 41.1 mmHg.</p><p><strong>Conclusion: </strong>The findings suggest that rapid ventricular pacing in cerebral aneurysm clipping is associated with a low risk of cardiac arrhythmia and myocardial injury, while facilitating high rates of complete aneurysm obliteration. This technique appears safe, with minimal impact on postoperative mortality and neurological outcomes.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"501"},"PeriodicalIF":2.5,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12152091/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144266881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}