Neurosurgical Review最新文献

{"title":"Cranial reconstruction in the literature: A CiteSpace visualized bibliometric analysis.","authors":"Jake Barsch, Erion Sulaj, John L Kilgallon, Robert Kamil, Nitesh V Patel, Ira M Goldstein","doi":"10.1007/s10143-025-03878-3","DOIUrl":"https://doi.org/10.1007/s10143-025-03878-3","url":null,"abstract":"<p><p>Cranioplasty (CP) research has shown that the material used for its bone flap formation is not standardized, with several viable options. The aim of this study was to explore the development of research in cranioplasty from a bibliometric perspective, with a focus on material choice, to elucidate trends in CP literature over time. Original studies and review articles on cranioplasty material related research were obtained from the Scopus database from 2014 to 2024. R package \"bibliometrix\" was used to summarize main findings, examine the occurrence of top keywords, and visualize collaboration networks between countries. VOSviewer software was applied to conduct both co-authorship and co-occurrence analyses, with CiteSpace used to identify the references and keywords with the strongest citation bursts. A total of 933 publications on cranioplasty material were included. An analysis of publication titles demonstrated an increase in CP for traumatic brain injury (TBI) post-2010 along with the growth of custom implants (i.e., \"patient-specific\"). Early citation bursts focused on the application of various materials, while later keywords concerned surgical complications and clinical outcomes. Several authors had significant bursts of contribution, and the United States was the largest contributor to the existing body of literature. This bibliometric study elucidated keyword trends as they relate to CP and material selection. It mapped a fundamental knowledge structure consisting of countries, institutions, authors, journals, and articles in the research field of cranioplasty material over the past ten years. The results provide a comprehensive perspective about the wider landscape of this research area.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"695"},"PeriodicalIF":2.5,"publicationDate":"2025-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145275206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Revealing the unique clinical characteristics of subarachnoid hemorrhage in young adults.","authors":"Hiroki Kobayashi, Takuma Maeda, Tomoya Kamide, Atsushi Hashio, Akio Teranishi, Yushiro Take, Tomomichi Kayahara, Kaima Suzuki, Hiroki Kurita","doi":"10.1007/s10143-025-03857-8","DOIUrl":"https://doi.org/10.1007/s10143-025-03857-8","url":null,"abstract":"","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"693"},"PeriodicalIF":2.5,"publicationDate":"2025-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145275332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic and prognostic role of serum/plasma and CSF amyloid beta peptide levels in traumatic brain injury: a systematic review and meta-analysis.","authors":"Fateme Mohammadifard, Sepehr Aghajanian, Ida Mohammadi, Shahryar Rajai Firouzabadi, Ali Baradaran Bagheri, Aladine A Elsamadicy","doi":"10.1007/s10143-025-03874-7","DOIUrl":"https://doi.org/10.1007/s10143-025-03874-7","url":null,"abstract":"<p><p>Amyloid beta (Aβ) peptides, particularly Aβ1-40 and Aβ1-42, have been implicated in TBI pathology as potential biomarkers for diagnosis and prognosis. This systematic review and meta-analysis aimed to evaluate differences in Aβ levels between TBI and non-TBI populations and their prognostic utility in both acute and chronic phases of TBI. A systematic search of MEDLINE, Scopus, and Web of Science was conducted up to October, 2024, with an updated search in July 2025. Studies assessing Aβ1-40 or Aβ1-42 in cerebrospinal fluid (CSF) or plasma of adults with TBI were included. Risk of bias was assessed using the Newcastle-Ottawa Scale. A random-effects meta-analysis was performed for between-group comparisons, with subgroup analyses based on biological compartment and sampling interval. 25 studies were included in the review and 11 underwent quantitative synthesis. Qualitative evaluation of studies suggested a positive correlation between Aβ1-42 and neurological status in moderate to severe TBI but not mild TBI or concussion. Plasma Aβ1-42 levels were significantly elevated in TBI patients within 24 h post-injury (SMD:0.91, 95%CI: [0.15-1.66 No significant differences were observed in CSF (SMD:-0.37, 95%CI: [-0.88-0.15]) or plasma Aβ1-42 (SMD:0.09, 95%CI: [-0.07-0.26]) or Aβ1-40 (SMD:0.10 95%CI: [-0.25-0.44]) levels beyond the first year following TBI. Aβ peptides, particularly Aβ1-42, appear to change acutely in plasma post-TBI but show no consistent long-term alterations in either plasma or CSF. The limited and heterogeneous evidence suggests only modest prognostic potential, with no current support for their clinical use as reliable biomarkers for diagnosis or prognosis in TBI. Further large-scale, standardized studies are warranted.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"694"},"PeriodicalIF":2.5,"publicationDate":"2025-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145275310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Subgroup analysis of pipeline Flow-Diverter devices in the treatment of intracranial aneurysms: A long-term real-world study involving 190 patients.","authors":"Huiwei Liu, Wenfeng Feng, Sheng Guan, Tianxiao Li, Guohua Mao, Aisha Maimaitili, Yongjie Ma, Donghai Wang, Ming Ye, Hongqi Zhang, Peng Zhang","doi":"10.1007/s10143-025-03830-5","DOIUrl":"https://doi.org/10.1007/s10143-025-03830-5","url":null,"abstract":"<p><p>The Pipeline is currently the most widely used flow-diverting device worldwide, yet research on its long-term efficacy remains limited, primarily based on small to medium-sized sample cohorts. The objective of this study was to evaluate the long-term safety and efficacy of the Pipeline device in treating intracranial aneurysms. Additionally, the study aimed to analyze the risk factors associated with long-term incomplete occlusion of the aneurysm and stenosis of the parent artery. This multicenter retrospective study included patients with intracranial aneurysms treated with the Pipeline flow-diverting device between 2015 and 2020. The analysis encompassed clinical and imaging outcomes, including clinical presentation, comorbidities, aneurysm characteristics, procedural details, and postoperative follow-up data. This study included 190 patients(122 females)with a mean age of 54.6 ± 11.7 years and 204 aneurysms. At one year postoperatively, the complete aneurysm occlusion rate was 69.9%, parent artery stenosis was 3.7%, and complications occurred in 3.3% of cases. During long-term follow-up, the occlusion rate increased to 93.1%, stenosis rose to 6.4%, and complications decreased to 2.1%. Three perforator occlusions were reported: two during the short-term follow-up and one during the long-term follow-up, resulting in severe impairment (mRS 4). The Pipeline flow-diverting device demonstrated favorable long-term safety and efficacy in the treatment of intracranial aneurysms, with no significant differences in safety or effectiveness between vertebral artery aneurysms and anterior circulation aneurysms. Statistical analysis identified advanced age and male gender as risk factors for long-term incomplete occlusion. Furthermore, the results suggest that postoperative antiplatelet therapy and imaging follow-up were continued for only one year, which is considered safe and effective.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"692"},"PeriodicalIF":2.5,"publicationDate":"2025-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145275389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bowel position does not preclude safe access in prone trans-psoas surgery.","authors":"Yi Yuen Wang, Gabriel Pokorny, Bryden Dawes","doi":"10.1007/s10143-025-03809-2","DOIUrl":"https://doi.org/10.1007/s10143-025-03809-2","url":null,"abstract":"<p><p>There are conflicting reports of the safety of surgical approach to the lateral spine during prone transpsoas surgery based on cadaveric and radiological data however a lack of true clinical data assessing safety is available. The objective of the study is to introduce a grading system assessing the safety of the surgical approach corridor in prone transpsoas surgery specifically in relation to bowel position, and the impact of the bowel position on bowel complications after prone transpsoas (PTP) surgery. Retrospective review of prospectively collated data. A 5-point grading system of bowel overlay was established. Consecutive patients undergoing prone transpsoas surgery across eighteen months were reviewed and graded using the 5-point grading system. Exclusions for prone transpsoas surgery was the configuration of the psoas musculature and retroperitoneal vessels. No consideration was given in regard to the bowel position pre-operatively. Analysis of grade in comparison to BMI, side of approach and levels were performed with the primary outcome measure being bowel injury. One hundred and forty patients were included in the study, all of whom underwent posterior pedicle screw fixation at 207 spinal levels. Mean age was 72.0 ± 9.9 with a female (N = 93) preponderance and an average BMI of 28.2 ± 4.9 kg/m². There was a correlation with higher bowel overlay grade with lower BMI. When categorized into high (grades 3-5) or low (0-2) overlay grades, 96 patients had a low-grade overlay (68.5%), and 44 patients had a high-grade overlay (31.43%). There was no bowel complication encountered in any grade of bowel overlay. The presence of bowel overlying the lateral disc in the prone position is not a contraindication to the PTP approach. While academically interesting, anatomical and radiological studies reporting narrowing of the retroperitoneal space in the prone position have little clinical relevance when considering the safety of the approach for PTP surgery.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"688"},"PeriodicalIF":2.5,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145275269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic factors in aneurysmal subarachnoid hemorrhage during the clazosentan era: a multicenter study using multivariate analyses and machine learning model.","authors":"Shinsuke Muraoka, Takashi Izumi, Kazuki Ishii, Issei Takeuchi, Masahiro Nishihori, Shunsaku Goto, Fumiaki Kanamori, Kenji Uda, Yusuke Sakamoto, Kinya Yokoyama, Kazuki Nishida, Basile Chretien, Ryuta Saito","doi":"10.1007/s10143-025-03858-7","DOIUrl":"https://doi.org/10.1007/s10143-025-03858-7","url":null,"abstract":"<p><strong>Background: </strong>Controlling delayed cerebral ischemia (DCI) is crucial for improving the prognosis in patients with aneurysmal subarachnoid hemorrhage (aSAH). This study aimed to identify prognostic factors in patients with aSAH in Japan.</p><p><strong>Methods: </strong>A multicenter, retrospective, observational cohort study was conducted from April 2021 to March 2024. Patients underwent surgical repair of ruptured aneurysms within 48 h of onset, followed by postoperative treatment with multiple drugs, including clazosentan and fasudil, to prevent cerebral vasospasm. The primary outcome was the proportion of patients with a good outcome, defined as a modified Rankin Scale score of 0 to 2 at discharge. Multivariate logistic regression and stepwise model selection were applied to identify prognostic factors. SHapley Additive exPlanations (SHAP) analysis was used to visualize the relative importance of predictors and their impact on outcomes.</p><p><strong>Results: </strong>Among 506 patients (mean age 63.5 years, 66.6% female), 53.0% achieved a favorable outcome. In multivariate analysis, treatment with clazosentan was associated with 1.84 times higher odds of a favorable outcome (p = 0.021), increasing to 1.97 when clazosentan was administered without fluid retention complications (p = 0.010). SHAP analysis further highlighted the impact of each factor on prognosis, identifying a lower WFNS grade, lower Fisher grade, younger age, clazosentan, cilostazol, and statin use as significant predictors of favorable outcomes.</p><p><strong>Conclusion: </strong>Clinical status at aSAH onset and age are uncontrollable factors; therefore, improving prognosis requires targeted prevention of DCI and effective management of brain edema. The administration of therapies such as clazosentan, cilostazol, and statins may contribute to favorable outcomes.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"690"},"PeriodicalIF":2.5,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145275329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endovascular thrombectomy for distal medium vessel occlusion stroke: A meta-analysis of randomized controlled trials.","authors":"Ali Mortezaei, Nadir Al-Saidi, Khaled M Taghlabi, Ibrahim Mohammadzadeh, Bardia Hajikarimloo, Mohammad Amin Habibi, Robert W Regenhardt, Joshua S Catapano, Jan-Karl Burkhardt, Redi Rahmani, Adam A Dmytriw, Amir H Faraji, Vivek S Yedavalli, Visish M Srinivasan","doi":"10.1007/s10143-025-03835-0","DOIUrl":"https://doi.org/10.1007/s10143-025-03835-0","url":null,"abstract":"<p><p>The efficacy of endovascular thrombectomy (EVT) for acute ischemic stroke (AIS) resulting from distal medium vessel occlusion (DMVO) remains uncertain. This systematic review and meta-analysis aimed to provide a comprehensive assessment of EVT in AIS due to DMVO, based on evidence derived from randomized controlled trials (RCTs). We systematically reviewed four electronic databases to find relevant studies. Risk ratios (RRs) and mean differences (MDs) with 95% confidence intervals (CIs) were calculated for categorical and continuous outcomes, respectively. Significant heterogenicity was resolved with leave-one-out influence analysis. There were 601 patients in the EVT plus best medical treatment (BMT) group and 623 patients in the BMT alone group. Findings showed a significantly higher rate of serious adverse events (RR = 1.3, 95%CI: 1.1-1.5, P < 0.01) and symptomatic intracranial hemorrhage (RR = 3.3, 95%CI: 1.8-5.9, P < 0.01) in thrombectomy than the control group. There was no significant difference between two groups in 90-day functional excellence (mRS 0-1), functional independence (mRS 0-2), and mortality. Subgroup analysis, including the three DMVO trials and the two secondary analyses of previous LVO RCTs, confirmed the prior findings. Leave-one-out influence analysis showed no significant heterogeneity in any primary and secondary outcomes. Our findings indicate that while EVT does not provide a significant advantage over BMT alone in improving functional outcomes for patients with DMVO, it is associated with an increased risk of hemorrhagic complications. These results underscore the importance of a cautious approach when considering EVT for DMVO and emphasize the need for further RCTs to optimize treatment strategies.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"691"},"PeriodicalIF":2.5,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145275370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparison of long-term outcomes between interposition with teflon and autologous muscle in microvascular decompression for trigeminal neuralgia.","authors":"Johann Klein, Barbara Carl","doi":"10.1007/s10143-025-03882-7","DOIUrl":"https://doi.org/10.1007/s10143-025-03882-7","url":null,"abstract":"<p><p>Microvascular decompression (MVD) is an established surgical procedure for treating classical trigeminal neuralgia (TN) by separating the trigeminal nerve from an offending vessel. Various materials can be used for interposition, Teflon being the standard in many centers. Autologous muscle is used as an alternative; however, comparative studies are sparse. We compared the outcomes of patients who underwent MVD for TN with either Teflon or muscle in the same center. We searched our database for patients who underwent MVD for TN between 2007 and 2024. The records were analyzed for outcome parameters, and patients or their relatives were contacted via phone if follow-up data were insufficient. Exclusion criteria included repeat MVD, lack of initial improvement after surgery, and loss to follow-up. The primary outcome parameter was treatment failure, defined as Barrow Neurological Institute (BNI) pain intensity score IV or V. 70 patients were identified. After applying the exclusion criteria, 48 were available for the outcome analysis, among whom 21 had received interposition with muscle and 27 with Teflon. The mean patient age was 65 years, 56.25% were female, and the pain was right-sided in 62.5% of patients. At a mean follow-up of 85 months, 12.5% had experienced treatment failure (14.29% in the muscle group and 11.11% in the Teflon group; p = 0.741). Kaplan-Meier analysis with log-rank test and logistic regression analysis revealed no significant differences. We found no differences in the outcomes of MVD for TN when either autologous muscle or Teflon was used. Both materials are appropriate for interposition.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"689"},"PeriodicalIF":2.5,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145275292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reducing medication errors in neurosurgery through clinical pharmacy interventions: a prospective observational study.","authors":"Aaron Lawson McLean, Anna Schlattl, Christian Senft, Michael Hartmann, Falko Schwarz","doi":"10.1007/s10143-025-03849-8","DOIUrl":"10.1007/s10143-025-03849-8","url":null,"abstract":"<p><p>Neurosurgical patient care is inherently complex, characterized by high rates of polypharmacy, advanced age, and significant comorbidities, all of which increase the risk of medication errors. These challenges are compounded by dynamic treatment plans and intensive care demands. In response, clinical pharmacist-led \"pharmaceutical interventions\" have emerged as a promising strategy to enhance medication safety. This study aimed to evaluate the impact of a structured weekly pharmacist-led medication review programme on prescribing practices and patient outcomes in a tertiary academic neurosurgical department. In this 12-month prospective study, a pharmacist performed weekly medication reviews on the neurosurgical ward and HDU. Interventions were coded in ADKA-DokuPIK and relayed to the team; 10% were re-audited to confirm uptake. The year was split into two six-month epochs to assess temporal trends. Administrative data from the intervention year were compared with a historical control for length of stay (LOS) and in-hospital mortality. Adverse-drug-event rates were not prospectively collected. A total of 996 interventions were documented among 1795 patients (0.55/patient). Intervention rates declined from 0.7 to 0.4 per patient between periods (p = 0.016), suggesting a learning effect. Implementation of recommendations was confirmed in 78% of audited cases. The most commonly affected drugs were pantoprazole (n = 77), amlodipine (n = 47), ciprofloxacin (n = 44). Median LOS decreased from 8.1 to 7.3 days (p = 0.032), the proportion of prolonged hospitalisations (> 14 days) fell from 18.9% to 14.8% (p = 0.002), and in-hospital mortality declined from 4.6% to 3.0% (p = 0.014). Routine integration of a clinical pharmacist into neurosurgical care was associated with fewer medication-related issues, measurable improvements in LOS and mortality, and evidence of progressive prescriber adaptation. These findings support broader implementation of pharmacist-led interventions in high-risk surgical environments. Controlled multicenter trials are warranted.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"687"},"PeriodicalIF":2.5,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12511136/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145251991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of artificial intelligence in predicting the clinical outcomes associated with different therapeutic approaches for vestibular schwannoma: A systematic review and meta-analysis.","authors":"Parisa Javadnia, Afshan Davari, Nadia Zameni, Amir Reza Bahadori, Sara Ahmadi, Sara Mohammadian, Abbas Tafakhori, Sajad Shafiee, Sara Ranji","doi":"10.1007/s10143-025-03841-2","DOIUrl":"https://doi.org/10.1007/s10143-025-03841-2","url":null,"abstract":"<p><strong>Introduction: </strong>Vestibular schwannoma is the most common neoplasm located at the skull base. The therapeutic strategy for managing vestibular schwannoma is formulated based on individual patient characteristics and specific imaging findings. Recently, there has been a growing interest in applying artificial intelligence (AI) to predict treatment outcomes in the field of neurosurgical oncology.</p><p><strong>Aim: </strong>This systematic review and meta-analysis aims to assess the efficacy of AI algorithms in predicting outcomes associated with various therapeutic strategies for vestibular schwannoma.</p><p><strong>Method and material: </strong>The study was conducted under PRISMA guidelines, involving comprehensive data extraction from multiple databases, specifically PubMed, Scopus, Embase, Web of Science, and the Cochrane Library, until January 31, 2025. Statistical analyses were performed using Comprehensive Meta-analysis (CMA) software version 3.0.</p><p><strong>Results: </strong>This systematic review and meta-analysis included data from 21 studies. AI algorithms achieved an area under the curve of 0.80 in predicting microsurgery outcomes, with an accuracy (positive predictions regardless of whether they are positive or negative) of 81.5% and sensitivity (true positive rate) of 83%. In subgroup analysis, AI showed better accuracy for forecasting facial function than for hearing preservation following microsurgery. For tumor control after radiosurgery, the AUC was 0.722 with an accuracy of 58.5%, while predicting tumor progression after conservative management yielded an AUC of 0.912 and 87.5% accuracy.</p><p><strong>Conclusion: </strong>AI algorithms can be valuable prognostic tools for evaluating outcomes across therapeutic interventions. Nonetheless, further prospective studies are essential to establish the optimal model for clinical application.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"685"},"PeriodicalIF":2.5,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145251949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}