Ryan Beerling Dolovac, Leon Lai, Jordan Jones, Christopher Ovenden, Jeremy Kam, Gina Arena, Mendel Castle-Kirszbaum
{"title":"The fundal cerebrospinal fluid cap in vestibular schwannoma surgery: a predictor of outcome after the retrosigmoid approach.","authors":"Ryan Beerling Dolovac, Leon Lai, Jordan Jones, Christopher Ovenden, Jeremy Kam, Gina Arena, Mendel Castle-Kirszbaum","doi":"10.1007/s10143-026-04305-x","DOIUrl":"https://doi.org/10.1007/s10143-026-04305-x","url":null,"abstract":"<p><p>The fundal cerebrospinal fluid (CSF) cap is a radiological finding correlating to a pocket of CSF lateral to vestibular schwannomas in the fundus of the internal acoustic meatus. Its presence may increase the likelihood of good facial nerve outcome and hearing preservation after microsurgical resection. A systematic review of the literature was performed. Studies that reported the association of a fundal fluid cap with postoperative outcomes including facial nerve outcome, hearing preservation and extent of resection were included. A total of 17 studies were included, comprising 2370 patients. Studies were generally at high risk of bias. The presence of a fundal cap was associated with significantly higher rate of good (HB I-II) facial nerve outcome after retrosigmoid approaches (OR 6.04; 95%CI 2.79-13.11), but not after translabyrinthine and middle fossa approaches. A fundal cap was associated with an increased rate of gross total resection (OR 2.13; CI: 1.51-3.00) and hearing preservation after retrosigmoid (OR 3.37; 95% CI: 2.32-4.90), but not middle fossa approaches (OR 1.47; 95% CI: 0.89-2.44). A fundal cap was also predictive of hearing preservation after radiosurgery. The fundal CSF cap is an important predictor of facial nerve function and hearing preservation after retrosigmoid craniotomy for vestibular schwannoma. Its importance in middle fossa and translabyrinthine surgery is less clear, which reflects the anatomical considerations of each approach. The presence or absence of a fundal cap should be documented preoperatively and used to guide more nuanced risk assessment for preoperative patient counselling.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"49 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13134987/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147818256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sotirios Apostolakis, Nikolaos Haliasos, Lampis C Stavrinou, Pantelis Stavrinou
{"title":"Sequesterectomy versus standard micro‑/open discectomy for lumbar disc herniation: a systematic review and meta-analysis.","authors":"Sotirios Apostolakis, Nikolaos Haliasos, Lampis C Stavrinou, Pantelis Stavrinou","doi":"10.1007/s10143-026-04304-y","DOIUrl":"https://doi.org/10.1007/s10143-026-04304-y","url":null,"abstract":"<p><p>Lumbar disk herniation is a common clinical entity affecting about 1% of the entire population every year. The purpose of the present work is to provide a systematic review and meta-analysis comparing the safety and efficiency of sequesterectomy and discectomy in the management of lumbar disk herniation. A systematic review and meta-analysis using the random effects method was performed. This search was applied through the 6th of March 2025 to PubMed, Scopus, Cochrane Central Register of Controlled Trials and the Directory of Open Access Journals. The data collected included patient demographics, spinal level at which the operation occurred, duration of operation and hospital stay, outcome, recurrence rate as well as potential immediate and delayed complications. A total of 18 original studies with a cumulative number of 4394 patients were identified. No statistically significant difference was found in the re-herniation and complication rate between the two groups (OR: 1.058, 95% CI: 0.726-1.541, p=.769 and OR: 1.399, 95% CI: 0.964-2.032, p=.077 respectively). The same applied for mean hospital stay (standard difference in means: 0.206, SE = 0.167, p= .219). In contrast, mean operating time was found to be significantly shorter in the sequesterectomy group than in the discectomy group (mean 58.086 min versus 72.885 min respectively). As or the patient reported outcomes, VAS score for back pain two years after the operation was the only index that was significantly higher in patients with discectomy (standard difference in means: 0.348, SE = 0.172, p= .04). Based on the available data, the two approaches do not differ in terms of risk of reherniation, reoperation rate and postoperative complications. Nevertheless, patients that have undergone sequesterectomy could potentially benefit from a more significant reduction in back pain in the long run.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"49 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147818271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Deep brain stimulation for clozapine-resistant schizophrenia: a systematic review of target-specific outcomes and stereotactic technical considerations.","authors":"Alivery Raihanada Armando, Achmad Fahmi, Heri Subianto, Agus Turchan, Wei Wang, Youheng Peng, Muhammad Fadhil Kamaruddin, Ramidha Syaharani, Ramadhani Rizki Zamzam, Nathania Maulina","doi":"10.1007/s10143-026-04296-9","DOIUrl":"https://doi.org/10.1007/s10143-026-04296-9","url":null,"abstract":"<p><p>Treatment-resistant schizophrenia (TRS) affects approximately 20-30% of patients, and a substantial proportion develop clozapine-resistant schizophrenia (CRS). Deep brain stimulation (DBS) has emerged as a potential neurosurgical intervention targeting dysfunctional cortico-striato-limbic circuitry. However, technical heterogeneity and limited clinical data constrain interpretation of outcomes. This systematic review was conducted in accordance with PRISMA guidelines and prospectively registered in PROSPERO (CRD420251080715). Seven electronic databases were searched from inception through January 31, 2025. Clinical studies investigating DBS in TRS or CRS were included. Methodological quality was assessed using Joanna Briggs Institute (JBI) tools. Data extraction emphasized stereotactic targeting methods, hardware configurations, stimulation parameters, and clinical outcomes. The total number of study is 6. We excluded paper by Manssuer 2023. The total study population comprises 21 patients. Seven studies involving 21 patients met inclusion criteria. Targets included the nucleus accumbens (NAcc; n = 11), substantia nigra (SNr; n = 1), habenula (HB; n = 2), subgenual cingulate (SCG; n = 4), subgenual anterior cingulate cortex (sgACC; n = 3). Reported PANSS total score changes ranged widely (11%-85.7%), reflecting substantial inter-individual variability and methodological limitations. Surgical complications occurred in 3 of 21 patients (14.2%), including infection and hemorrhage. All cases utilized open-loop stimulation and conventional cylindrical leads. Current evidence suggests a preliminary therapeutic signal for DBS in highly selected CRS patients, particularly with NAcc targeting. However, conclusions remain limited by small sample sizes, technical heterogeneity, and absence of controlled trials. Future investigations should prioritize standardized stereotactic reporting, volumetric lead reconstruction, and long-term safety assessment within specialized neurosurgical research settings. PROSPERO CRD420251080715.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"49 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13135008/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147818284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"MRA-based aneurysm occlusion assessment in the early phase after flow diverter treatment: a multicenter retrospective study focusing on the impact of aneurysm diameter.","authors":"Satoshi Koizumi, Masaaki Shojima, Kei Yanai, Satoshi Kiyofuji, Shogo Dofuku, Daisuke Sato, Motoyuki Umekawa, Shigeta Fujitani, Hideaki Ono, Satoru Miyawaki, Nobuhito Saito","doi":"10.1007/s10143-026-04315-9","DOIUrl":"https://doi.org/10.1007/s10143-026-04315-9","url":null,"abstract":"<p><strong>Background: </strong>Although it is well-known that most aneurysms occlude within 1 year after flow diverter (FD) treatment, the time course to occlusion, especially in the early period, has not been adequately studied.</p><p><strong>Methods: </strong>This study included patients treated with FDs between April 2018 and December 2024 and underwent at least 3 months of imaging follow-up with MRA. The primary outcome was aneurysm occlusion without rupture during follow-up. Cumulative aneurysm occlusion rates were assessed using repetitive time-of-flight and ultrashort echo-time MRA. Predictors of aneurysm occlusion were analyzed with special interests to patient backgrounds, anatomical factors including aneurysm diameter, and procedural details.</p><p><strong>Results: </strong>This study included 119 patients (male: female ratio, 15:104; mean age, 58 ± 14 years; average diameter, 10.8 mm). During the median follow-up of 12 months, the cumulative occlusion rates at 3, 6, and 12 months were 15%, 48%, and 79%, respectively. Receiver operating characteristic analysis identified the diameter threshold of 10.9 mm to best predict its occlusion, and aneurysms larger than this cutoff showed lower cumulative occlusion rates (P = 0.002 [log-rank test], hazard ratio 0.49 [P = 0.003]). In the multivariable Cox hazard model, an increase in aneurysm diameter (Hazard ratio 0.92, P = 0.002) was a preventive factor for aneurysm occlusion, whereas adjunctive coiling (Hazard ratio 2.05, P = 0.009) significantly promoted the occlusion rate.</p><p><strong>Conclusions: </strong>In postoperative follow-up using repetitive MRA, larger aneurysms exhibited the trend to occlude slower after FD treatment, whereas adjunctive coiling promoted the time course to aneurysm occlusion. Future prospective studies are warranted to investigate technical factors to further promote aneurysm occlusion.</p><p><strong>Clinical trial number: </strong>UMIN000057450.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"49 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13133222/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147818215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Federico Valeri, Simone Antonio de Sanctis, Gianluca Trevisi, Jacopo Ciccani, Sabrina Chiloiro, Antonella Giampietro, Antonio Bianchi, Rosalinda Calandrelli, Ciro Mazzarella, Simona Gaudino, Mario Rigante, Marco Gessi, Pier Paolo Mattogno, Liverana Lauretti, Francesco Doglietto
{"title":"Evolution of surgical management and functional outcomes of craniopharyngiomas: a systematic review and meta-analysis.","authors":"Federico Valeri, Simone Antonio de Sanctis, Gianluca Trevisi, Jacopo Ciccani, Sabrina Chiloiro, Antonella Giampietro, Antonio Bianchi, Rosalinda Calandrelli, Ciro Mazzarella, Simona Gaudino, Mario Rigante, Marco Gessi, Pier Paolo Mattogno, Liverana Lauretti, Francesco Doglietto","doi":"10.1007/s10143-026-04308-8","DOIUrl":"10.1007/s10143-026-04308-8","url":null,"abstract":"","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"49 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13128730/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147777251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emily M Persons, Brianna L Hines, Marcela Herrera, Emma R Lesser, Muralidharan Anbalagan, Mitesh Dave, Samir Anadkat, Georgi P Georgiev, Aaron S Dumont, Joe Iwanaga, R Shane Tubbs
{"title":"Osborne's ligament: Anatomical study with application to better understanding ulnar nerve compression at the elbow.","authors":"Emily M Persons, Brianna L Hines, Marcela Herrera, Emma R Lesser, Muralidharan Anbalagan, Mitesh Dave, Samir Anadkat, Georgi P Georgiev, Aaron S Dumont, Joe Iwanaga, R Shane Tubbs","doi":"10.1007/s10143-026-04307-9","DOIUrl":"https://doi.org/10.1007/s10143-026-04307-9","url":null,"abstract":"","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"49 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13121326/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147777316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction to: Potential for multidrug combination therapy in patients with World Federation of Neurological Surgeons grade V subarachnoid hemorrhage.","authors":"Fuki Goto, Fumihiro Kawakita, Koichi Hakozaki, Kazuaki Aoki, Hidenori Suzuki","doi":"10.1007/s10143-026-04302-0","DOIUrl":"https://doi.org/10.1007/s10143-026-04302-0","url":null,"abstract":"","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"49 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147777199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Beste Gülsuna, Parth Patel, Max W Melville, Burak Özaydin, Uttam Verma, Nimer Adeeb, Shyian S Jen, Michael J Feldman, Andrew M Bauer, Hakeem J Shakir
{"title":"Flow diverting stents for anterior communicating artery aneurysms: A systematic review and meta-analysis of safety, efficacy, and anatomic determinants.","authors":"Beste Gülsuna, Parth Patel, Max W Melville, Burak Özaydin, Uttam Verma, Nimer Adeeb, Shyian S Jen, Michael J Feldman, Andrew M Bauer, Hakeem J Shakir","doi":"10.1007/s10143-026-04306-w","DOIUrl":"https://doi.org/10.1007/s10143-026-04306-w","url":null,"abstract":"","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"49 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147777249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joonho Byun, Min Su Park, Hyun Keun Kim, Woo Keun Kwon, Chang Hwa Ham, Haewon Roh, Hyun Jun Jo, Won Ki Yoon, Taek Hyun Kwon, Jong Hyun Kim
{"title":"Clinical implications of false-negative and false-positive intraoperative transcranial motor evoked potentials in brain tumor surgery.","authors":"Joonho Byun, Min Su Park, Hyun Keun Kim, Woo Keun Kwon, Chang Hwa Ham, Haewon Roh, Hyun Jun Jo, Won Ki Yoon, Taek Hyun Kwon, Jong Hyun Kim","doi":"10.1007/s10143-026-04288-9","DOIUrl":"https://doi.org/10.1007/s10143-026-04288-9","url":null,"abstract":"","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"49 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147777239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}