Neurosurgical Review最新文献

{"title":"Leveraging artificial intelligence in the peer review of neurosurgical research articles.","authors":"Ali A Mohamed, Daniel Colome, Jack Yang, Emma C Sargent, Gabriel Flores-Milan, Zachary Sorrentino, Akshay Sharma, Owoicho Adogwa, Stephen Pirris, Brandon Lucke-Wold","doi":"10.1007/s10143-025-03783-9","DOIUrl":"10.1007/s10143-025-03783-9","url":null,"abstract":"<p><p>The traditional peer review process is time-consuming and can delay the dissemination of critical research. This study evaluates the effectiveness of artificial intelligence (AI) in predicting the acceptance or rejection of neurosurgical manuscripts, offering a possible solution to optimize the process. Neurosurgical preprints from Preprint.org and medRxiv.org were analyzed. Published preprints were compared to those presumed not accepted after remaining on preprint servers for over 12 months. Each article was uploaded to ChatGPT 4o, Gemini, and Copilot with the prompt: \"Based on the literature up to the date this article was posted, will it be accepted or rejected for publication following peer review? Please provide a yes or no answer.\" AI predictive accuracy and journal metrics were assessed between preprints that were accepted or presumed to be not accepted. A total of 51 preprints (31 skull base, 20 spine) were included, with 28 published and 23 presumed not accepted. The average impact factor and cite score for accepted preprints were 4.36 ± 2.07 and 6.38 ± 3.67 for skull base and 3.48 ± 1.08 and 4.83 ± 1.37 for spine topics. Across all AI models, there were no significant differences in journal metrics between preprints predicted to be accepted or not accepted (p > 0.05). Overall, AI models had significantly low performance, with accuracy ranging from 40 to 66.67% (p < 0.001). Current AI models exhibit moderate accuracy in predicting peer review outcomes. Future AI models, developed in collaboration with journals and with authors' consent, could access a more balanced dataset, enhancing accuracy and streamlining the peer review process.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"631"},"PeriodicalIF":2.5,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144962905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence and risk factors of hyponatremia after transsphenoidal surgery: a systematic meta-analysis.","authors":"Kevin L Webb, Charles E Reilly, Mickayla L Hinkle, Yuki Shinya, Jamie J Van Gompel, Fredric B Meyer","doi":"10.1007/s10143-025-03784-8","DOIUrl":"10.1007/s10143-025-03784-8","url":null,"abstract":"<p><p>The transsphenoidal approach to sellar lesions is a mainstay technique in modern neurosurgical treatment of pituitary adenomas. One prominent complication following transsphenoidal surgery is the development of postoperative hyponatremia, frequently necessitating additional medical management and hospital readmission. However, the precise incidence and risk factors of postoperative hyponatremia remain unclear in the current literature. We conducted a systematic meta-analysis of 104 studies (31,676 patients) to clarify the incidence of postoperative hyponatremia and associated hospital readmission, as well as to summarize conflicting findings regarding significant risk factors of postoperative hyponatremia. The overall incidence of postoperative hyponatremia following transsphenoidal surgery was 13.3% [95% Confidence Interval (CI): 11.8-14.7%; 96 studies]. The rate of hospital readmission due to postoperative hyponatremia was 3.3% [95% CI: 2.7-3.9%; 33 studies]. Factors such as infundibular stalk deviation angle, plasma copeptin level, and Knosp grades served as more reliable predictors of postoperative hyponatremia. In contrast, conventional demographic and surgical parameters such as patient age, body mass index, sex, and extent of resection were not consistently identified as significant predictive factors. Secondary analyses revealed that prophylactic fluid restriction significantly reduced the incidence of postoperative hyponatremia from ~ 13.1% to ~ 4.0% (Odds Ratio 3.39 [95% CI; 2.18-5.26, Z = 5.545, P < 0.001]. This meta-analysis establishes definitive 'benchmarks' for anticipated complications after transsphenoidal surgery while highlighting important factors such as prophylactic fluid restriction protocols as a key source of inter-study variability. In addition, this study summarizes the congruence of the predictive factors thought to be influential in leading to postoperative hyponatremia, highlighting key areas of (dis)agreement.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"630"},"PeriodicalIF":2.5,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144962898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Awake versus asleep craniotomy for eloquent glioblastoma: a systematic review and meta-analysis.","authors":"Susan I Honeyman, Alexandros Boukas, Melika Akhbari, Blessing Okoli, Richard Stacey, Vasileios Apostolopoulos, Puneet Plaha","doi":"10.1007/s10143-025-03787-5","DOIUrl":"10.1007/s10143-025-03787-5","url":null,"abstract":"<p><p>Awake craniotomy (AC) can aid in preserving neurological function through intraoperative mapping of sensorimotor and language functions. It has been associated with increased extent of resection (EOR) and reduced neurological deficits in glioma patients. Most studies focused on low grade tumours and there remains limited evidence assessing utility of AC for glioblastoma (GB). This systematic review evaluates current evidence for safety and efficacy of GB resection under AC versus general anaesthetic (GA) conditions. We carried out a systematic review and meta-analysis of original studies assessing comparative outcomes of supratentorial GB resection via AC versus GA. Studies included patients > 18 years of age, with histopathological diagnosis of Grade 4 GB affecting an eloquent location. Medline, Embase and Pubmed were searched from inception to the 30th of June 2025. The outcomes assessed included: EOR, rates of temporary and permanent post-operative neurological deficits, survival, and functional outcomes. Eleven studies were included, with 1355 patients (402 AC and 953 GA resections). AC achieved greater percentage EOR (MD = 7.55 [CI 2.94-12.15], p = 0.001), and non-significant increase in rates of gross total resection (OR = 1.66 [CI 0.64-4.35], p = 0.30). The risk of developing a post-operative neurological deficit was significantly lower with AC (OR = 0.55 [CI:0.36-0.85], p = 0.008). Overall survival (HR = 7.99 [CI 2.29-13.69], p = 0.007) was significantly increased with AC but there was no significant difference in progression-free survival (HR = 2.03 [CI -1.32-5.37], p = 0.23). AC for eloquently located GB is associated with improved EOR, survival and lower risk of neurological complications. When feasible, AC should be considered for eloquent GB resection.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"628"},"PeriodicalIF":2.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144962851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The efficacy of machine learning algorithms in evaluating factors associated with shunt-dependent hydrocephalus after subarachnoid hemorrhage: a systematic review and meta-analysis.","authors":"Parisa Javadnia, Nila Salimi, Bita Shokri, Yousef Ramazani, Mehdi Moradinazar, Neda Khaledian, Ehsan Alimohammadi","doi":"10.1007/s10143-025-03773-x","DOIUrl":"10.1007/s10143-025-03773-x","url":null,"abstract":"<p><p>The identification of factors associated with chronic shunt-dependent hydrocephalus (CSDH) following spontaneous subarachnoid hemorrhage (SAH) remains challenging, despite numerous studies. Early recognition of patients at higher risk for requiring shunt placement is important for optimizing management strategies. This systematic review and meta-analysis evaluated the efficacy of machine learning (ML) algorithms in analyzing datasets related to CSDH post-SAH, assessing performance metrics such as sensitivity, accuracy, and specificity. A systematic review was conducted across five databases (PubMed, Scopus, Cochrane Library, Embase, and Web of Science) to identify studies employing ML to analyze factors associated with CSDH following SAH. Data extraction included ML techniques, input features, and performance metrics such as area under the receiver operating characteristic curve (AUC-ROC), accuracy, sensitivity, specificity, precision, and F1 score. Two independent reviewers extracted and organized the data, including details on machine learning models, validation processes, and metrics. Out of 993 reviewed studies, five met the inclusion criteria for analyzing ML models in relation to CSDH post-SAH. The pooled AUC-ROC across these models was 0.79 (95% CI: 0.78-0.81), with moderate heterogeneity (I² = 42.58%, Q (19) = 34.79, p = 0.01). No significant differences in AUC-ROC were observed between linear, tree-based, and deep learning models (Q (2) = 0.99, p = 0.61). Studies utilizing fewer than 10 input features showed a lower pooled AUC-ROC of 0.78, whereas those with more than 10 features achieved a higher AUC-ROC of 0.82, with heterogeneity of 7.52% and 66.53%, respectively. Machine learning algorithms can assist in identifying factors associated with the development of chronic hydrocephalus following spontaneous SAH through analysis of clinical datasets. Incorporating a greater number of relevant risk factors may further improve the performance of these ML models in understanding high-risk patient profiles.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"629"},"PeriodicalIF":2.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144962932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors associated with rapid progression of scoliosis following intraspinal lesion resection in laminoplasty patients.","authors":"Mingquan Liu, Yiji Li, Xingang Zhao, Dongao Zhang, Cong Liang, Yinqian Wang, Kun Wu, Tao Fan","doi":"10.1007/s10143-025-03782-w","DOIUrl":"https://doi.org/10.1007/s10143-025-03782-w","url":null,"abstract":"<p><p>Scoliosis is a rare complication of intraspinal lesions. However, in patients with pre-existing scoliosis who have undergone lesion resection via laminoplasty, the subsequent progression of this deformity and its associated risk factors remain poorly understood. The objective of this study is to investigate the incidence of progressive scoliosis and identify risk factors contributing to its rapid progression in patients who underwent laminoplasty for resection of intraspinal lesions. This study retrospectively analyzed data from patients who underwent laminoplasty for resection of intraspinal lesions between January 2014 to December 2023. Multivariate logistic regression analysis was used to assess the statistical relationship between postoperative scoliosis progression and clinical, radiographic, and surgical-related variables. Fifty-two patients met the inclusion criteria for this study. During a follow-up of 28.5 (IQR,12-59.25) months, 32 patients (61.5%) exhibited scoliosis progression, with a mean progression of (16.3 ± 17.7) °. Notably, 16 patients (30.8%) demonstrated a progression exceeding 10° per annum. In the correlation analysis, variables such as age, Risser index, tumor location, scoliosis degree, the extent of laminoplasty, as well as postoperative syringomyelia, hypertonia and modified McCormick Scale (MMS) were associated with the rapid progression of scoliosis. However, multivariate analysis only identified three independent risk factors: preoperative curvature > 35°, laminoplasty involving ≥ 5 spinal segments, and postoperative hypertonia, which increased the odds of rapid progression by 5.2-, 4.8-, and 6.3-fold, respectively. In conclusion, after laminoplasty for resection of intraspinal lesions, 61.5% of patients with pre-existing scoliosis experienced progression of the deformity, and 30.8% of patients had rapid progression of scoliosis. A Cobb angle exceeding 35°, laminoplasty involving more than 5 vertebral segments, and postoperative hypertonia are all factors that increase the risk of rapid progression of scoliosis after surgery.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"627"},"PeriodicalIF":2.5,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144962924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical characteristics, imaging, treatment, and prognosis of dural arteriovenous fistula presented with Parkinsonism- a systematic review.","authors":"Haodong Li, Yongle Wang, Ling Li, Xiaoyuan Niu, Jin Zhang","doi":"10.1007/s10143-025-03738-0","DOIUrl":"10.1007/s10143-025-03738-0","url":null,"abstract":"<p><p>Dural arteriovenous fistulas (DAVFs) are abnormal arteriovenous shunts that occur between intracranial arteries and venous sinuses, meningeal veins, or cortical veins. These lesions can lead to pathological changes such as cerebral edema, increased intracranial pressure, metabolic dysfunction in the brain, venous sinus thrombosis, and vascular rupture with hemorrhage. Clinically, DAVFs rarely present as Parkinsonism, often coexisting with dementia. While there are numerous global reports of DAVF with cognitive impairment as the primary symptom, cases of DAVF presenting predominantly with Parkinsonism are exceedingly rare. Secondary Parkinsonism in DAVF may be associated with deep venous reflux and venous hypertension involving the basal ganglia. Severe dementia symptoms may overshadow Parkinsonian features, complicating the clinical diagnosis of DAVF-induced Parkinsonism. This article aims to review published case reports and series to summarize the clinical and imaging characteristics (CT, MRI, and angiography) of these patients, evaluate the quality of the cases, and hypothesize potential pathophysiological mechanisms, providing clinical guidance for the management of DAVF-associated Parkinsonism.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"625"},"PeriodicalIF":2.5,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144962908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radial-specific catheters for neuroendovascular procedures: A systematic review and meta-analysis.","authors":"Ali Mortezaei, Nadir Al-Saidi, Ibrahim Mohammadzadeh, Jamal Behnood, Muhammed Amir Essibayi, Khaled M Taghlabi, Ahmed Abdelsalam, Mohammad Amin Habibi, Bardia Hajikarimloo, Luis Guada-Delgado, Ram Saha, Redi Rahmani, Amir H Faraji, Robert M Starke","doi":"10.1007/s10143-025-03765-x","DOIUrl":"10.1007/s10143-025-03765-x","url":null,"abstract":"<p><strong>Background: </strong>Despite a radial-first approach in many neurointerventions, there are no systematic reviews and meta-analysis which comprehensively assess radial-specific catheter for neuroendovascular procedures. A systematic literature search was conducted through four electronic databases based on PRISMA 2020 guideline. Risk of bias was assessed employing Risk of Bias in Non-randomized Studies of Interventions (ROBINS-I) tool. A total of eleven studies with 990 patients using Armadillo, RIST, Zoom RDL, and BMX 81 catheters were included. The Armadillo showed significantly lower failure to catheterize the target vessel (0.0% vs. 3.04%, P = 0.036) than RIST. The Zoom RDL catheter had relatively higher failure rate of 10.3%. There was no significant difference between the Armadillo and RIST catheters in procedure-related complications. There were no reported cases of arterial spasm or hemorrhage for Armadillo catheter. RIST catheter had a 3.2% rate of neurological complications, a 3.1% rate of transfemoral conversion, and a 1.8% rate of hematoma. The BMX 81 catheter had a 2.5% rate of arterial vasospasm and a 5% rate of procedure-related complications. The Zoom RDL catheter had consistent rates of procedure-related, transfemoral conversion, and neurological complications, all at 6.9%, with insufficient data on other complications.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"626"},"PeriodicalIF":2.5,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12394285/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144962937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes following traumatic brain injury in patients with Pre-Injury antiplatelets versus anticoagulants: A systematic review and Meta-Analysis.","authors":"Stavros Matsoukas, Sean Inzerillo, Arianne Boylan, Patrick C Reid, Konstantinos Margetis, Divaldo Camara","doi":"10.1007/s10143-025-03780-y","DOIUrl":"https://doi.org/10.1007/s10143-025-03780-y","url":null,"abstract":"<p><p>Management of traumatic brain injury (TBI) patients on pre-TBI antithrombotic medications poses a clinical challenge in everyday practice. However, the safety profiles of antiplatelets (APs) have not been systematically studied and compared to anticoagulants (ACs) in this patient population. In this PRISMA-compliant systematic review the EMBASE and MEDLINE databases were systematically queried to identify comparative studies in patients with TBI and pre-injury AP and AC medications. Meta-analysis with random effect models were conducted for all outcomes. Forest plots were utilized to visually represent each study's effect and pooled estimates. Intracranial hemorrhage rates were statistically significantly higher for patients on single AP vs. AC (AP 19.7%; AC 9.3%; OR 1.35; CI 1.02-1.78; I² 49%, P = 0.03). Cumulative mortality rates (AP 6%; AC 2.5%; OR 0.72; CI; 0.39-1.32 I² 55%, P = 0.3), worsening ICH rates (AP 0.3%; AC 0.4%; OR 0.85; CI 0.16-4.55; I² 0%, P = 0.8) and need for neurosurgical intervention (AP 2.6%; AC 0.9%; OR 1.27; CI 0.48-3.39; I² 68%, P = 0.6) were comparable. For elderly patients (> 65 years old), ICH rates were comparable between groups (AP 46.8%; AC 28.3%; OR 1.03; CI 0.57-1.85; I² 66%, P = 0.9) and mortality was statistically significantly lower in the AP group (AP 19.4%; AC 29.5%; OR 0.46; CI 0.31-0.69; I² 0%, P < 0.001). Single pre-TBI AP carries more risk for ICH compared to AC. Mortality risk, worsening ICH risk and need for neurosurgical intervention are comparable. For elderly patients, ICH rates were comparable, but APs were associated with lower mortality.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"622"},"PeriodicalIF":2.5,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144962860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical outcomes in elderly patients with vestibular schwannoma: a retrospective cohort study.","authors":"Binghan Zhang, Haoming Geng, Yuanchen Tang, Dong Liu, Xiaolong Wu, Tian Lan, Yiqiang Zhou, Xu Wang, Gang Song, Jiantao Liang","doi":"10.1007/s10143-025-03776-8","DOIUrl":"10.1007/s10143-025-03776-8","url":null,"abstract":"<p><p>This study aims to evaluate the surgical outcomes and clinical differences of elderly vestibular schwannoma (VS) patients (> 65 years), compared with non-elderly patients, focusing on baseline characteristics, preoperative symptoms, postoperative facial and auditory functions, and quality of life. A retrospective study was conducted on 59 elderly and 59 non-elderly patients, matched 1:1 by tumor size. All patients underwent retro-sigmoid microsurgery performed by the same neurosurgical team during the period from December 2018 to September 2023. Data including demographics, imaging findings, clinical symptoms, hearing, facial nerve function, and surgical outcomes were collected. Regular follow-up was conducted to assess postoperative recovery. Elderly patients had a longer disease course (median: 36 months) and a higher proportion with poor preoperative ASA scores (P < 0.001). Hearing loss was the most common symptom in the elderly group (n = 47, 79.7%), who were also more likely to have hydrocephalus (15.3%, P = 0.027) and balance disorder (25.4%, P = 0.006). Gross total resection rates were significantly lower in elderly patients (55.9% vs. 78.0%, P = 0.011). Postoperative and follow-up facial nerve function showed no statistical difference between groups, but hearing preservation was poor in both. Compared to non-elderly patients, elderly patients had longer disease courses, more preoperative symptoms, and slower postoperative recovery. Despite poorer general conditions and more comorbidities, advanced age should not be a contraindication for surgery, as long-term outcomes are favorable when individualized patient factors are considered.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"621"},"PeriodicalIF":2.5,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144962883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Machine learning-based models and radiomics: can they be reliable predictors for meningioma recurrence? A systematic review and meta-analysis.","authors":"Behnaz Niroomand, Ibrahim Mohammadzadeh, Bardia Hajikarimloo, Mohammad Amin Habibi, Shahin Mohammadzadeh, Amir Mohammad Bahri, Mohammad Hassan Bagheri, Abdulrahman Albakr, Brij S Karmur, Hamid Borghei-Razavi","doi":"10.1007/s10143-025-03744-2","DOIUrl":"10.1007/s10143-025-03744-2","url":null,"abstract":"<p><strong>Background: </strong>Predicting recurrence in meningioma patients is vital for improving long-term outcomes and tailoring personalized treatment strategies. While traditional diagnostic methods have advanced, accurately forecasting recurrence remains a persistent and critical challenge. This study explores the cutting-edge application of artificial intelligence (AI)-based models, which seamlessly integrate clinical, radiological, and pathological data, offering a transformative approach to enhancing the reliability and precision of recurrence prediction.</p><p><strong>Methods: </strong>Eligible studies were identified through a comprehensive search of the Web of Science, Scopus, PubMed, and Embase databases. Extracted and synthesized metrics for analysis included accuracy, sensitivity, specificity, precision, F1 score, and area under the curve (AUC). Out of 2,971 studies screened, six met the inclusion criteria for systematic review, and three were included in the meta-analysis.</p><p><strong>Results: </strong>The pooled sensitivity and specificity of AI models were 0.86 [95% CI: 0.78-0.92] and 0.86 [95% CI: 0.81-0.90], respectively. The positive diagnostic likelihood ratio (DLR) was 6.33 [95% CI: 4.42-9.08], and the negative DLR was 0.16 [95% CI: 0.09-0.27]. The diagnostic odds ratio (DOR) was estimated at 40.11 [95% CI: 19.30-83.37], with a diagnostic score of 3.69 [95% CI: 2.96-4.42] and a pooled area under the curve (AUC) of 0.93 [95% CI: 0.90-0.95]. Subgroup analysis showed comparable sensitivity (RF: 0.88; LR: 0.84) and specificity (RF: 0.84; LR: 0.84) with no significant heterogeneity (I² = 0%).</p><p><strong>Conclusions: </strong>These findings highlight the potential of AI-based models to predict meningioma recurrence, offer superior diagnostic accuracy, and aid clinical decision-making. Integrating clinical, radiological, and pathological data through AI-driven models demonstrates substantial promise in enhancing the reliability and efficiency of recurrence forecasting.</p>","PeriodicalId":19184,"journal":{"name":"Neurosurgical Review","volume":"48 1","pages":"623"},"PeriodicalIF":2.5,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144962867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}