Nature PhysicsPub Date : 2025-06-26DOI: 10.1038/s41567-025-02936-3
Atsushi Takahagi, Takamasa Hirai, Abdulkareem Alasli, Sang J. Park, Hosei Nagano, Ken-ichi Uchida
{"title":"Observation of the transverse Thomson effect","authors":"Atsushi Takahagi, Takamasa Hirai, Abdulkareem Alasli, Sang J. Park, Hosei Nagano, Ken-ichi Uchida","doi":"10.1038/s41567-025-02936-3","DOIUrl":"https://doi.org/10.1038/s41567-025-02936-3","url":null,"abstract":"<p>The Thomson effect refers to volumetric heating or cooling in a conductor when a charge current and a temperature gradient are applied in the same direction. Similarly, it is expected that a conductor will be heated or cooled when a charge current, a temperature gradient and a magnetic field are applied in orthogonal directions. This phenomenon, referred to as the transverse Thomson effect, has not been experimentally observed. Here we report the observation of this effect in a semimetallic Bi<sub>88</sub>Sb<sub>12</sub> alloy with thermoelectric imaging. We can switch between heating or cooling by changing the direction of the magnetic field. Our experiments and analyses reveal the essential difference between the conventional and transverse Thomson effects. Whereas the former depends sorely on the temperature derivative of the Seebeck coefficient, the latter depends on the temperature derivative and the magnitude of the Nernst coefficient. The observation of the transverse Thomson effect provides a new concept for active thermal management technologies.</p>","PeriodicalId":19100,"journal":{"name":"Nature Physics","volume":"9 1","pages":""},"PeriodicalIF":19.6,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144488468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nature PhysicsPub Date : 2025-06-26DOI: 10.1038/s41567-025-02956-z
Andrew T. Pierce, Yonglong Xie, Jeong Min Park, Zhuozhen Cai, Kenji Watanabe, Takashi Taniguchi, Pablo Jarillo-Herrero, Amir Yacoby
{"title":"Tunable interplay between light and heavy electrons in twisted trilayer graphene","authors":"Andrew T. Pierce, Yonglong Xie, Jeong Min Park, Zhuozhen Cai, Kenji Watanabe, Takashi Taniguchi, Pablo Jarillo-Herrero, Amir Yacoby","doi":"10.1038/s41567-025-02956-z","DOIUrl":"https://doi.org/10.1038/s41567-025-02956-z","url":null,"abstract":"<p>In systems with multiple energy bands, the interplay between electrons with different effective masses drives correlated phenomena that do not occur in single-band systems. Magic-angle twisted trilayer graphene is a tunable platform for exploring such effects, hosting both heavy electrons in its flat bands and delocalized light Dirac electrons in dispersive bands. Superconductivity in this system spans a wider range of phase space than moiré materials without dispersive bands, suggesting that interband interactions influence the stabilization of correlated phases. Here we investigate the interplay between the light and heavy electrons in magic-angle twisted trilayer graphene by performing local compressibility measurements with a scanning single-electron-transistor microscope. We establish that weak incompressibility features near several integer moiré band fillings host a finite population of light Dirac electrons at the Fermi level, despite a gap opening in the flat band sector. At higher magnetic field near charge neutrality, we find a phase transition sequence that is robust over nearly 10 μm but exhibits complex spatial dependence. Calculations establish that the Dirac sector can be viewed as flavour analogous to the spin and valley degrees of freedom.</p>","PeriodicalId":19100,"journal":{"name":"Nature Physics","volume":"34 1","pages":""},"PeriodicalIF":19.6,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144488469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nature PhysicsPub Date : 2025-06-26DOI: 10.1038/s41567-025-02935-4
Alexander Floroni, Noël Yeh Martín, Thomas Matreux, Laura I. Weise, Sheref S. Mansy, Hannes Mutschler, Christof B. Mast, Dieter Braun
{"title":"Membraneless protocell confined by a heat flow","authors":"Alexander Floroni, Noël Yeh Martín, Thomas Matreux, Laura I. Weise, Sheref S. Mansy, Hannes Mutschler, Christof B. Mast, Dieter Braun","doi":"10.1038/s41567-025-02935-4","DOIUrl":"https://doi.org/10.1038/s41567-025-02935-4","url":null,"abstract":"<p>In living cells, a complex mixture of biomolecules is assembled within and across membranes. This non-equilibrium state is maintained by sophisticated protein machinery, which imports food molecules, removes waste products and orchestrates cell division. However, it remains unclear how this complex cellular machinery emerged and evolved. Here we show how the molecular contents of a cell can be coupled in a coordinated way to non-equilibrium heat flow. A temperature difference across a water-filled pore assembled the core components of a modern cell, which could then activate the gene expression. The mechanism arose from the interplay of convection and thermophoresis, both driven by the same heat source. The cellular machinery of protein synthesis from DNA via RNA was triggered as a direct result of the concentration of cell components. The same non-equilibrium setting continued to attract food molecules from an adjacent fluid stream, keeping the cellular molecules in a confined pocket protected against diffusion. Our results show how a simple non-equilibrium physical process can assemble the many different molecules of a cell and trigger its basic functions. The framework provides a membrane-free environment to bridge the long evolutionary times from an RNA world to a protein-based cell-like proto-metabolism.</p>","PeriodicalId":19100,"journal":{"name":"Nature Physics","volume":"17 1","pages":""},"PeriodicalIF":19.6,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144488467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nature PhysicsPub Date : 2025-06-24DOI: 10.1038/s41567-025-02941-6
Jayne Thompson
{"title":"Quantum neural networks can be normal","authors":"Jayne Thompson","doi":"10.1038/s41567-025-02941-6","DOIUrl":"https://doi.org/10.1038/s41567-025-02941-6","url":null,"abstract":"As many classical neural networks get larger, they can be described as Gaussian processes, the generalization of the normal distribution to infinite dimensions. A similar connection has now been proven for quantum neural networks.","PeriodicalId":19100,"journal":{"name":"Nature Physics","volume":"36 1","pages":""},"PeriodicalIF":19.6,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144370459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nature PhysicsPub Date : 2025-06-20DOI: 10.1038/s41567-025-02947-0
Fan Liu, Bo Gao, Liran Lei, Shuainan Liu, Hui Li, Ming Guo
{"title":"Intercellular flow dominates the poroelasticity of multicellular tissues","authors":"Fan Liu, Bo Gao, Liran Lei, Shuainan Liu, Hui Li, Ming Guo","doi":"10.1038/s41567-025-02947-0","DOIUrl":"https://doi.org/10.1038/s41567-025-02947-0","url":null,"abstract":"<p>The mechanical characteristics of cells and extracellular matrices—such as elasticity, surface tension and viscosity—can influence diseases such as fibrosis and tumour metastasis. Multicellular tissues have traditionally been modelled as viscoelastic materials, which overlooked the abundance of intercellular space and intercellular flow within the structure. Although intercellular flow can substantially impact development and disease progression, its role in the mechanical behaviour of tissues remains unclear. Here we show that fluid transport via the intercellular space determines the immediate mechanical response of tissues upon deformation. We directly measure the mechanical response of multicellular tissues by applying parallel plate compression via a tailored micro-mechanics platform. We find that both cultured three-dimensional cell spheroids and native mouse pancreatic islets exhibit apparent poroelastic behaviour over a timescale of up to a minute. These findings highlight the fundamental role of interstitial fluid transport in the mechanics of multicellular systems and could help identify potential physical regulators of development and diseases, as well as strategies for engineering multicellular living systems.</p>","PeriodicalId":19100,"journal":{"name":"Nature Physics","volume":"8 1","pages":""},"PeriodicalIF":19.6,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144329003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nature PhysicsPub Date : 2025-06-19DOI: 10.1038/s41567-025-02939-0
Julien Madéo, Keshav M. Dani
{"title":"Floquet states in graphene revealed at last","authors":"Julien Madéo, Keshav M. Dani","doi":"10.1038/s41567-025-02939-0","DOIUrl":"https://doi.org/10.1038/s41567-025-02939-0","url":null,"abstract":"Time-resolved photoemission shows evidence of Floquet states in graphene, resolving a long-standing debate and unlocking engineering of quantum phases with light in semi-metals.","PeriodicalId":19100,"journal":{"name":"Nature Physics","volume":"12 1","pages":""},"PeriodicalIF":19.6,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144319359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nature PhysicsPub Date : 2025-06-19DOI: 10.1038/s41567-025-02922-9
Bin Gao, Félix Desrochers, David W. Tam, Diana M. Kirschbaum, Paul Steffens, Arno Hiess, Duy Ha Nguyen, Yixi Su, Sang-Wook Cheong, Silke Paschen, Yong Baek Kim, Pengcheng Dai
{"title":"Neutron scattering and thermodynamic evidence for emergent photons and fractionalization in a pyrochlore spin ice","authors":"Bin Gao, Félix Desrochers, David W. Tam, Diana M. Kirschbaum, Paul Steffens, Arno Hiess, Duy Ha Nguyen, Yixi Su, Sang-Wook Cheong, Silke Paschen, Yong Baek Kim, Pengcheng Dai","doi":"10.1038/s41567-025-02922-9","DOIUrl":"https://doi.org/10.1038/s41567-025-02922-9","url":null,"abstract":"<p>The three-dimensional pyrochlore lattice of corner-sharing tetrahedra can host a quantum spin ice, a quantum analogue of the classical spin ice found in other pyrochlore compounds. This state can manifest a quantum spin liquid, and indeed, these compounds are predicted to have emergent gauge fields that produce linearly dispersing collective magnetic excitations near zero energy, in addition to the presence of higher-energy spinon excitations. Here we use polarized neutron scattering experiments on single crystals of the Ce<sub>2</sub>Zr<sub>2</sub>O<sub>7</sub> pyrochlore. We find evidence for magnetic excitations near zero energy, in addition to signatures of spinons at higher energies. Furthermore, we perform heat capacity measurements and find behaviour consistent with the cubic-in-temperature dependence expected for linearly dispersing gapless bosonic modes. Comparing the observed magnetic excitations with theoretical calculations, we argue that Ce<sub>2</sub>Zr<sub>2</sub>O<sub>7</sub> is a strong candidate for a dipolar–octupolar quantum spin ice with dominant dipolar Ising interactions.</p>","PeriodicalId":19100,"journal":{"name":"Nature Physics","volume":"38 1","pages":""},"PeriodicalIF":19.6,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144319425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nature PhysicsPub Date : 2025-06-18DOI: 10.1038/s41567-025-02937-2
Yu Shi
{"title":"From actin to action","authors":"Yu Shi","doi":"10.1038/s41567-025-02937-2","DOIUrl":"https://doi.org/10.1038/s41567-025-02937-2","url":null,"abstract":"Cells undergo structural rearrangements to enable migration and changes in morphology. A study using reconstituted actomyosin revealed that these earthquake-like events are driven by F-actin organization and active stress generation.","PeriodicalId":19100,"journal":{"name":"Nature Physics","volume":"29 1","pages":""},"PeriodicalIF":19.6,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144311801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nature PhysicsPub Date : 2025-06-18DOI: 10.1038/s41567-025-02934-5
Claudia Politi
{"title":"Driven quantum fluids sound like supersolids","authors":"Claudia Politi","doi":"10.1038/s41567-025-02934-5","DOIUrl":"https://doi.org/10.1038/s41567-025-02934-5","url":null,"abstract":"Quantum gases develop modulated patterns when subjected to a continuous drive. An experiment has now demonstrated that, in a driven quantum system, the sound propagates with two distinct speeds, reflecting both superfluid and crystalline properties — a feature of supersolidity.","PeriodicalId":19100,"journal":{"name":"Nature Physics","volume":"39 1","pages":""},"PeriodicalIF":19.6,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144311800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nature PhysicsPub Date : 2025-06-18DOI: 10.1038/s41567-025-02919-4
Zachary Gao Sun, Nathan Zimmerberg, Patrick Kelly, Carlos Floyd, Garegin Papoian, Michael Murrell
{"title":"Feedback between F-actin organization and active stress governs criticality and energy localization in the cell cytoskeleton","authors":"Zachary Gao Sun, Nathan Zimmerberg, Patrick Kelly, Carlos Floyd, Garegin Papoian, Michael Murrell","doi":"10.1038/s41567-025-02919-4","DOIUrl":"https://doi.org/10.1038/s41567-025-02919-4","url":null,"abstract":"<p>Self-organized criticality can occur in earthquakes, avalanches and biological processes, and is characterized by intermittent, scale-free energy dissipation. In living cells, the actin cytoskeleton undergoes dynamic structural reorganization, particularly during migration and division, where molecular motors generate mechanical stresses that drive large dissipative events. However, the mechanisms governing these critical transitions remain unclear. Here we show that cytoskeletal criticality emerges from the interplay between F-actin organization and active stress generation. Our study focuses on a minimal actomyosin system in vitro, which is composed of F-actin filaments, myosin II motors and nucleation-promoting factors. By systematically varying the actin connectivity and nematic order, we demonstrate that ordered and sparsely connected networks exhibit exponential stress dissipation, whereas disordered and highly connected networks show heavy-tailed distributions of energy release and the 1/<i>f</i> noise characteristic of self-organized criticality. Increased disorder leads to stress localization, shifting force propagation into stiffer mechanical modes, reminiscent of Anderson localization in condensed-matter systems. Furthermore, we show that network architecture directly regulates the myosin II filament size, establishing a chemical–mechanical feedback loop that modulates criticality. Our findings provide insights into the collective cytoskeletal dynamics, energy localization and cellular self-organization.</p>","PeriodicalId":19100,"journal":{"name":"Nature Physics","volume":"590 1","pages":""},"PeriodicalIF":19.6,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144312211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}