Nature PhysicsPub Date : 2025-08-26DOI: 10.1038/s41567-025-02996-5
Christian P. N. Tanner, Vivian R. K. Wall, Joshua Portner, Ahhyun Jeong, Avishek Das, James K. Utterback, Leo M. Hamerlynck, Jonathan G. Raybin, Matthew J. Hurley, Nicholas Leonard, Rebecca B. Wai, Jenna A. Tan, Mumtaz Gababa, Chenhui Zhu, Eric Schaible, Christopher J. Tassone, David T. Limmer, Samuel W. Teitelbaum, Dmitri V. Talapin, Naomi S. Ginsberg
{"title":"Enhancing nanoscale charged colloid crystallization near a metastable liquid binodal","authors":"Christian P. N. Tanner, Vivian R. K. Wall, Joshua Portner, Ahhyun Jeong, Avishek Das, James K. Utterback, Leo M. Hamerlynck, Jonathan G. Raybin, Matthew J. Hurley, Nicholas Leonard, Rebecca B. Wai, Jenna A. Tan, Mumtaz Gababa, Chenhui Zhu, Eric Schaible, Christopher J. Tassone, David T. Limmer, Samuel W. Teitelbaum, Dmitri V. Talapin, Naomi S. Ginsberg","doi":"10.1038/s41567-025-02996-5","DOIUrl":"https://doi.org/10.1038/s41567-025-02996-5","url":null,"abstract":"<p>Achieving predictive control over crystallization using non-classical nucleation while avoiding kinetic traps would be a step towards designing materials with new functionalities. We address these challenges by inducing the bottom-up assembly of nanocrystals into ordered arrays, or superlattices. Using electrostatics—rather than density—to tune the interactions between particles, we watch self-assembly proceed through a metastable liquid phase. We systematically investigate the phase behaviour as a function of quench conditions in situ and in real time using small-angle X-ray scattering. By fitting to colloid, liquid and superlattice models, we extract the time evolution of each phase and the system phase diagram, which we find to be consistent with short-range attractive interactions. Using the predictive power of the phase diagram, we establish control of the self-assembly rate over three orders of magnitude, and we identify one- and two-step self-assembly regimes, with only the latter implicating the metastable liquid as an intermediate. The presence of the metastable liquid increases the superlattice formation rate relative to the equivalent one-step pathway, and the superlattice order increases with the rate, revealing a generalizable kinetic strategy for promoting and enhancing ordered assembly.</p>","PeriodicalId":19100,"journal":{"name":"Nature Physics","volume":"185 1","pages":""},"PeriodicalIF":19.6,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144900283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nature PhysicsPub Date : 2025-08-26DOI: 10.1038/s41567-025-02983-w
Yucheng Ye, Zheng Hao, Jingyi Luo, Wai Hei Lam, Zheng Liu, Xiang David Li, Yuanliang Zhai, Yuan Lin, Shih-Chieh Ti
{"title":"Tubulin isotypes of C. elegans harness the mechanosensitivity of the lattice for microtubule luminal accessibility","authors":"Yucheng Ye, Zheng Hao, Jingyi Luo, Wai Hei Lam, Zheng Liu, Xiang David Li, Yuanliang Zhai, Yuan Lin, Shih-Chieh Ti","doi":"10.1038/s41567-025-02983-w","DOIUrl":"10.1038/s41567-025-02983-w","url":null,"abstract":"Microtubules are hollow cylindrical cytoskeletal polymers of laterally associated protofilaments that contain head-to-tail aligned ɑ/β-tubulin heterodimers. Although the exposed microtubule exterior is readily accessible to proteins, the mechanism governing the accessibility of the confined microtubule lumen to luminal particles remains unknown. Here we show that certain tubulin family proteins (isotypes) facilitate luminal accessibility because of the mechanical properties and lateral interactions that they confer to the microtubules. We characterized the microtubules reconstituted from defined compositions of Caenorhabditis elegans tubulin isotypes. These tubulin isotypes form microtubules with comparable protofilament numbers but different luminal accessibility. We further revealed the role of tubulin isotypes in regulating the strength of inter-protofilament lateral interactions, which determines luminal accessibility through the mechanosensitivity of reversible protofilament separation. Deformation of the microtubule lattice, which generates stresses exceeding the strength of the lateral interactions, creates gaps between adjacent protofilaments, enhancing the accessibility of the lumen. Together, our findings uncovered the tubulin isotype-dependent mechanical plasticity that confers force sensitivity to the microtubule lattice and modulates the energy barrier for luminal proteins to access the lumen. Proteins interact with both the exterior and interior of microtubules. Here the relationship between microtubule building blocks and the accessibility of the microtubule interior to proteins is clarified.","PeriodicalId":19100,"journal":{"name":"Nature Physics","volume":"21 9","pages":"1420-1430"},"PeriodicalIF":18.4,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144901820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nature PhysicsPub Date : 2025-08-25DOI: 10.1038/s41567-025-03019-z
N. G. Holmes
{"title":"Invest in science education research to make science open to all","authors":"N. G. Holmes","doi":"10.1038/s41567-025-03019-z","DOIUrl":"10.1038/s41567-025-03019-z","url":null,"abstract":"Attacks on Diversity, Equity and Inclusion efforts expose the need for science education research.","PeriodicalId":19100,"journal":{"name":"Nature Physics","volume":"21 9","pages":"1350-1350"},"PeriodicalIF":18.4,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144900165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nature PhysicsPub Date : 2025-08-25DOI: 10.1038/s41567-025-02980-z
Yohalie Kalukula, Marine Luciano, Gleb Simanov, Guillaume Charras, David B. Brückner, Sylvain Gabriele
{"title":"The actin cortex acts as a mechanical memory of morphology in confined migrating cells","authors":"Yohalie Kalukula, Marine Luciano, Gleb Simanov, Guillaume Charras, David B. Brückner, Sylvain Gabriele","doi":"10.1038/s41567-025-02980-z","DOIUrl":"10.1038/s41567-025-02980-z","url":null,"abstract":"Cell migration in narrow microenvironments occurs in numerous physiological processes. It involves successive cycles of confinement and release that drive important morphological changes. However, it remains unclear whether migrating cells can retain a memory of their past morphological states that could potentially facilitate their navigation through confined spaces. We demonstrate that local geometry governs a switch between two cell morphologies, thereby facilitating cell passage through long and narrow gaps. We combined cell migration assays on standardized microsystems with biophysical modelling and biochemical perturbations to show that migrating cells have a long-term memory of past confinement events. The morphological cell states correlate across transitions through actin cortex remodelling. These findings indicate that mechanical memory in migrating cells plays an active role in their migratory potential in confined environments. Cells often navigate through confined spaces. Now it is shown that cells retain a mechanical memory of previous confinement events, which makes them more efficient at migrating through narrow microenvironments.","PeriodicalId":19100,"journal":{"name":"Nature Physics","volume":"21 9","pages":"1451-1461"},"PeriodicalIF":18.4,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144900285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nature PhysicsPub Date : 2025-08-22DOI: 10.1038/s41567-025-02970-1
F. Rabec, G. Chauveau, G. Brochier, S. Nascimbene, J. Dalibard, J. Beugnon
{"title":"Bloch oscillations of a soliton in a one-dimensional quantum fluid","authors":"F. Rabec, G. Chauveau, G. Brochier, S. Nascimbene, J. Dalibard, J. Beugnon","doi":"10.1038/s41567-025-02970-1","DOIUrl":"https://doi.org/10.1038/s41567-025-02970-1","url":null,"abstract":"<p>The motion of a quantum system under an external force often challenges classical intuition. A notable example is the dynamics of a single particle in a periodic potential, which undergoes Bloch oscillations under the action of a constant force. Similar oscillations can also occur in one-dimensional quantum fluids without a lattice. The generalization of Bloch oscillations to a weakly bounded ensemble of interacting particles has so far been limited to the experimental study of the two-particle case, where the observed period is halved compared to the single-particle case. In this work, we observe the oscillations of the position of a mesoscopic solitonic wave packet—consisting of approximately 1,000 atoms—in a one-dimensional Bose gas subjected to a constant uniform force and in the absence of a lattice potential. The oscillation period scales inversely with the number of atoms, revealing its collective nature. We demonstrate the role of the phase coherence of the quantum bath in which the wave packet moves and investigate the underlying topology of the associated superfluid currents. Our measurements highlight the periodicity of the dispersion relation of collective excitations in one-dimensional quantum systems.</p>","PeriodicalId":19100,"journal":{"name":"Nature Physics","volume":"38 1","pages":""},"PeriodicalIF":19.6,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144900161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nature PhysicsPub Date : 2025-08-22DOI: 10.1038/s41567-025-03004-6
Max L. Prichard, Zengli Ba, Ivan Morera, Benjamin M. Spar, David A. Huse, Eugene Demler, Waseem S. Bakr
{"title":"Magnon-polarons in the Fermi–Hubbard model","authors":"Max L. Prichard, Zengli Ba, Ivan Morera, Benjamin M. Spar, David A. Huse, Eugene Demler, Waseem S. Bakr","doi":"10.1038/s41567-025-03004-6","DOIUrl":"https://doi.org/10.1038/s41567-025-03004-6","url":null,"abstract":"<p>The interplay of magnetic excitations and itinerant charge carriers is a ubiquitous phenomenon in strongly correlated electron systems. A key theoretical question is understanding the renormalization of the magnon quasiparticle, a collective spin excitation, upon doping a magnetic insulator. Here we observe a new type of quasiparticle—a magnon-Fermi-polaron—arising from the dressing of a magnon with the doped holes of a cold-atom Fermi–Hubbard system. Using Raman excitation with controlled momentum in a doped, spin-polarized band insulator, we address the spectroscopic properties of the magnon-polaron. In an undoped system with strong interactions, photoexcitation produces magnons, whose properties are accurately described by spin-wave theory. We measure the evolution of the photoexcitation spectra as we move away from this limit to produce magnon-polarons due to dressing of the magnons by charge excitations. We observe a shift in the polaron energy with doping that is strongly dependent on the injected momentum, accompanied by a reduction of spectral weight in the probed energy window. We anticipate that the technique introduced here, which is the analogue of inelastic neutron scattering, will provide atomic quantum simulators with access to the dynamics of a wide variety of excitations in strongly correlated phases.</p>","PeriodicalId":19100,"journal":{"name":"Nature Physics","volume":"31 1","pages":""},"PeriodicalIF":19.6,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144901755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nature PhysicsPub Date : 2025-08-21DOI: 10.1038/s41567-025-03002-8
V. G. Matsos, C. H. Valahu, M. J. Millican, T. Navickas, X. C. Kolesnikow, M. J. Biercuk, T. R. Tan
{"title":"Universal quantum gate set for Gottesman–Kitaev–Preskill logical qubits","authors":"V. G. Matsos, C. H. Valahu, M. J. Millican, T. Navickas, X. C. Kolesnikow, M. J. Biercuk, T. R. Tan","doi":"10.1038/s41567-025-03002-8","DOIUrl":"https://doi.org/10.1038/s41567-025-03002-8","url":null,"abstract":"<p>Conventional approaches towards creating a large-scale, fault-tolerant quantum computer require an error correction scheme that uses multiple physical qubits to encode one logical qubit of protected quantum information. A key limiting factor in realizing error-corrected quantum information processing is the large ratio of physical-to-logical qubits required by many error correction codes, outstripping the size of near-term devices. The Gottesman–Kitaev–Preskill (GKP) code offers hardware efficiency at the cost of increased encoding complexity by encoding a logical qubit into a single quantum harmonic oscillator. Building on earlier demonstrations of GKP-encoded operations, we realize an entangling gate on GKP logical qubits. Our experiments use an optimal control strategy that deterministically implements a universal set of energy-preserving logical gates on finite-energy GKP states encoded in the mechanical motions of a trapped ion. We also directly generate a GKP Bell state starting from vacuum. Our approach is compatible with existing hardware architectures, demonstrating the potential for optimal control techniques with advanced encoding schemes to accelerate the path towards large-scale fault-tolerant quantum information processing.</p>","PeriodicalId":19100,"journal":{"name":"Nature Physics","volume":"416 1","pages":""},"PeriodicalIF":19.6,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144899897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nature PhysicsPub Date : 2025-08-21DOI: 10.1038/s41567-025-02991-w
{"title":"Extended native gate sets to unlock the performance of quantum processors","authors":"","doi":"10.1038/s41567-025-02991-w","DOIUrl":"10.1038/s41567-025-02991-w","url":null,"abstract":"Quantum operations are modelled as unitary matrices, yet experimental implementations have been restricted to only a few gate types. This fundamental limitation has now been overcome using a scheme that combines frequency control with microwave driving, enabling universal implementation of arbitrary two-qubit operations.","PeriodicalId":19100,"journal":{"name":"Nature Physics","volume":"21 9","pages":"1361-1362"},"PeriodicalIF":18.4,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144899967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nature PhysicsPub Date : 2025-08-21DOI: 10.1038/s41567-025-03011-7
Zhubing Jia
{"title":"Quantum logic with bosonic error correction","authors":"Zhubing Jia","doi":"10.1038/s41567-025-03011-7","DOIUrl":"https://doi.org/10.1038/s41567-025-03011-7","url":null,"abstract":"The most commonly pursued quantum error-correction schemes encode quantum information using multiple two-level qubits. Now, two logical qubits have been encoded in the infinite-dimensional bosonic motional degrees of freedom of a trapped ion.","PeriodicalId":19100,"journal":{"name":"Nature Physics","volume":"16 1","pages":""},"PeriodicalIF":19.6,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144899895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Efficient implementation of arbitrary two-qubit gates using unified control","authors":"Zhen Chen, Weiyang Liu, Yanjun Ma, Weijie Sun, Ruixia Wang, He Wang, Huikai Xu, Guangming Xue, Haisheng Yan, Zhen Yang, Jiayu Ding, Yang Gao, Feiyu Li, Yujia Zhang, Zikang Zhang, Yirong Jin, Haifeng Yu, Jianxin Chen, Fei Yan","doi":"10.1038/s41567-025-02990-x","DOIUrl":"10.1038/s41567-025-02990-x","url":null,"abstract":"The set of quantum logic gates that can be easily implemented is fundamental to the performance of quantum computers, as it governs the accuracy of basic quantum operations and dictates the complexity of implementing quantum algorithms. Traditional approaches to extending gate sets often require operating devices outside the ideal parameter regimes used to realize qubits, leading to increased control complexity while offering only a limited set of gates. Here we experimentally demonstrate a unified and versatile gate scheme capable of generating arbitrary two-qubit gates using only an exchange interaction and qubit driving on a superconducting quantum processor. We achieve high fidelities averaging 99.38% across a wide range of commonly used two-qubit unitaries, enabling precise multipartite entangled state preparation. Furthermore, we successfully produce a B gate, which efficiently synthesizes the entire family of two-qubit gates. Our results establish that fully exploiting the capabilities of the exchange interaction can yield a comprehensive and highly accurate gate set. With maximum expressivity, optimal gate time, demonstrated high fidelity and easy adaption to other quantum platforms, our unified control scheme offers the prospect of improved performance in quantum hardware and algorithm development. The efficiency of a quantum computer depends on which basic operations it can implement. Now a scheme that can implement any two-qubit logic gate has been demonstrated on a superconducting architecture.","PeriodicalId":19100,"journal":{"name":"Nature Physics","volume":"21 9","pages":"1489-1496"},"PeriodicalIF":18.4,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/s41567-025-02990-x.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144851616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}